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Joseph Takahashi
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27
Turek, Fred
25
Vitaterna, Martha Hotz
11
Antoch, Marina
11
Shimomura, Kazuhiro
10
Siepka, Sandra
10
Pinto, Lawrence
8
McDearmon, Erin
8
King, DP
8
Kornhauser, Jon
8
Wilsbacher, Lisa
8
Ko, Caroline
7
Zee, Phyllis
7
Mayo, Kelly
6
Lowrey, Phillip
6
Sangoram, AM
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All Publications
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2009: Solberg Woods Leah C; Ahmadiyeh Nasim; Baum Amber; Shimomura Kazuhiro; Li Qian; Steiner Donald F; Turek Fred W; Takahashi Joseph S; Churchill Gary A; Redei Eva E
Identification of genetic loci involved in diabetes using a rat model of depression.
Mammalian genome : official journal of the International Mammalian Genome Society 2009;20(8):486-97.
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2009: Ramsey Kathryn Moynihan; Yoshino Jun; Brace Cynthia S; Abrassart Dana; Kobayashi Yumiko; Marcheva Biliana; Hong Hee-Kyung; Chong Jason L; Buhr Ethan D; Lee Choogon; Takahashi Joseph S; Imai Shin-Ichiro; Bass Joseph
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.
Science (New York, N.Y.) 2009;324(5927):651-4.
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2008: Takahashi Joseph S; Shimomura Kazuhiro; Kumar Vivek
Searching for genes underlying behavior: lessons from circadian rhythms.
Science (New York, N.Y.) 2008;322(5903):909-12.
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2008: Takahashi Joseph S; Hong Hee-Kyung; Ko Caroline H; McDearmon Erin L
The genetics of mammalian circadian order and disorder: implications for physiology and disease.
Nature reviews. Genetics 2008;9(10):764-75.
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2008: Green Carla B; Takahashi Joseph S; Bass Joseph
The meter of metabolism.
Cell 2008;134(5):728-42.
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2008: Wu Chunlei; Delano David L; Mitro Nico; Su Stephen V; Janes Jeff; McClurg Phillip; Batalov Serge; Welch Genevieve L; Zhang Jie; Orth Anthony P; Walker John R; Glynne Richard J; Cooke Michael P; Takahashi Joseph S; Shimomura Kazuhiro; Kohsaka Akira; Bass Joseph; Saez Enrique; Wiltshire Tim; Su Andrew I
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.
PLoS genetics 2008;4(5):e1000070.
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2007: Pinto Lawrence H; Invergo Brandon; Shimomura Kazuhiro; Takahashi Joseph S; Troy John B
Interpretation of the mouse electroretinogram.
Documenta ophthalmologica. Advances in ophthalmology 2007;115(3):127-36.
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2007: McCarthy John J; Andrews Jessica L; McDearmon Erin L; Campbell Kenneth S; Barber Brigham K; Miller Brooke H; Walker John R; Hogenesch John B; Takahashi Joseph S; Esser Karyn A
Identification of the circadian transcriptome in adult mouse skeletal muscle.
Physiological genomics 2007;31(1):86-95.
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2007: Siepka Sandra M; Yoo Seung-Hee; Park Junghea; Song Weimin; Kumar Vivek; Hu Yinin; Lee Choogon; Takahashi Joseph S
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.
Cell 2007;129(5):1011-23.
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2007: Liu Andrew C; Welsh David K; Ko Caroline H; Tran Hien G; Zhang Eric E; Priest Aaron A; Buhr Ethan D; Singer Oded; Meeker Kirsten; Verma Inder M; Doyle Francis J; Takahashi Joseph S; Kay Steve A
Intercellular coupling confers robustness against mutations in the SCN circadian clock network.
Cell 2007;129(3):605-16.
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2007: McClurg Phillip; Janes Jeff; Wu Chunlei; Delano David L; Walker John R; Batalov Serge; Takahashi Joseph S; Shimomura Kazuhiro; Kohsaka Akira; Bass Joseph; Wiltshire Tim; Su Andrew I
Genomewide association analysis in diverse inbred mice: power and population structure.
Genetics 2007;176(1):675-83.
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2007: Roybal Kole; Theobold David; Graham Ami; DiNieri Jennifer A; Russo Scott J; Krishnan Vaishnav; Chakravarty Sumana; Peevey Joseph; Oehrlein Nathan; Birnbaum Shari; Vitaterna Martha H; Orsulak Paul; Takahashi Joseph S; Nestler Eric J; Carlezon William A; McClung Colleen A
Mania-like behavior induced by disruption of CLOCK.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6406-11.
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2007: Miller Brooke H; McDearmon Erin L; Panda Satchidananda; Hayes Kevin R; Zhang Jie; Andrews Jessica L; Antoch Marina P; Walker John R; Esser Karyn A; Hogenesch John B; Takahashi Joseph S
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3342-7.
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2007: Hong Hee-Kyung; Chong Jason L; Song Weimin; Song Eun Joo; Jyawook Amira A; Schook Andrew C; Ko Caroline H; Takahashi Joseph S
Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior.
PLoS genetics 2007;3(2):e33.
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2007: Pinto Lawrence H; Vitaterna Martha H; Shimomura Kazuhiro; Siepka Sandra M; Balannik Victoria; McDearmon Erin L; Omura Chiaki; Lumayag Stephen; Invergo Brandon M; Glawe Brett; Cantrell Donald R; Inayat Samsoon; Olvera Marissa A; Vessey Kirstan A; McCall Maureen A; Maddox Dennis; Morgans Catherine W; Young Brandon; Pletcher Mathew T; Mullins Robert F; Troy John B; Takahashi Joseph S
Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.
Visual neuroscience 2007;24(1):111-23.
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2007: Siepka S M; Yoo S-H; Park J; Lee C; Takahashi J S
Genetics and neurobiology of circadian clocks in mammals.
Cold Spring Harbor symposia on quantitative biology 2007;72():251-9.
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2006: McDearmon Erin L; Patel Kush N; Ko Caroline H; Walisser Jacqueline A; Schook Andrew C; Chong Jason L; Wilsbacher Lisa D; Song Eun J; Hong Hee-Kyung; Bradfield Christopher A; Takahashi Joseph S
Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice.
Science (New York, N.Y.) 2006;314(5803):1304-8.
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2006: Miller Brooke H; Olson Susan Losee; Levine Jon E; Turek Fred W; Horton Teresa H; Takahashi Joseph S
Vasopressin regulation of the proestrous luteinizing hormone surge in wild-type and Clock mutant mice.
Biology of reproduction 2006;75(5):778-84.
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2006: Ko Caroline H; Takahashi Joseph S
Molecular components of the mammalian circadian clock.
Human molecular genetics 2006;15 Spec No 2():R271-7.
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2006: Green Carla B; Takahashi Joseph S
Xenobiotic metabolism in the fourth dimension: PARtners in time.
Cell metabolism 2006;4(1):3-4.
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2006: Vitaterna Martha Hotz; Ko Caroline H; Chang Anne-Marie; Buhr Ethan D; Fruechte Ethan M; Schook Andrew; Antoch Marina P; Turek Fred W; Takahashi Joseph S
The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9327-32.
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2006: Vitaterna Martha Hotz; Pinto Lawrence H; Takahashi Joseph S
Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice.
Trends in neurosciences 2006;29(4):233-40.
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2006: Moran Jennifer L; Bolton Andrew D; Tran Pamela V; Brown Alison; Dwyer Noelle D; Manning Danielle K; Bjork Bryan C; Li Cheng; Montgomery Kate; Siepka Sandra M; Vitaterna Martha Hotz; Takahashi Joseph S; Wiltshire Tim; Kwiatkowski David J; Kucherlapati Raju; Beier David R
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.
Genome research 2006;16(3):436-40.
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2005: Pinto Lawrence H; Vitaterna Martha H; Shimomura Kazuhiro; Siepka Sandra M; McDearmon Erin L; Fenner Deborah; Lumayag Stephen L; Omura Chiaki; Andrews Anne W; Baker Matthew; Invergo Brandon M; Olvera Marissa A; Heffron Edward; Mullins Robert F; Sheffield Val C; Stone Edwin M; Takahashi Joseph S
Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.
Visual neuroscience 2005;22(5):619-29.
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2005: Brzezinski Joseph A; Brown Nadean L; Tanikawa Atsuhiro; Bush Ronald A; Sieving Paul A; Vitaterna Martha H; Takahashi Joseph S; Glaser Tom
Loss of circadian photoentrainment and abnormal retinal electrophysiology in Math5 mutant mice.
Investigative ophthalmology & visual science 2005;46(7):2540-51.
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2005: Antoch Marina P; Kondratov Roman V; Takahashi Joseph S
Circadian clock genes as modulators of sensitivity to genotoxic stress.
Cell cycle (Georgetown, Tex.) 2005;4(7):901-7.
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2005: McClung Colleen A; Sidiropoulou Kyriaki; Vitaterna Martha; Takahashi Joseph S; White Francis J; Cooper Donald C; Nestler Eric J
Regulation of dopaminergic transmission and cocaine reward by the Clock gene.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9377-81.
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2005: Turek Fred W; Joshu Corinne; Kohsaka Akira; Lin Emily; Ivanova Ganka; McDearmon Erin; Laposky Aaron; Losee-Olson Sue; Easton Amy; Jensen Dalan R; Eckel Robert H; Takahashi Joseph S; Bass Joseph
Obesity and metabolic syndrome in circadian Clock mutant mice.
Science (New York, N.Y.) 2005;308(5724):1043-5.
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2005: Gorbacheva Victoria Y; Kondratov Roman V; Zhang Renliang; Cherukuri Srujana; Gudkov Andrei V; Takahashi Joseph S; Antoch Marina P
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3407-12.
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2005: Yoo Seung-Hee; Ko Caroline H; Lowrey Phillip L; Buhr Ethan D; Song Eun-joo; Chang Suhwan; Yoo Ook Joon; Yamazaki Shin; Lee Choogon; Takahashi Joseph S
A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2608-13.
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2005: Prolo Laura M; Takahashi Joseph S; Herzog Erik D
Circadian rhythm generation and entrainment in astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(2):404-8.
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2005: Low-Zeddies Sharon S; Takahashi Joseph S
Mouse chimeras and their application to circadian biology.
Methods in enzymology 2005;393():478-92.
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2005: Siepka Sandra M; Takahashi Joseph S
Methods to record circadian rhythm wheel running activity in mice.
Methods in enzymology 2005;393():230-9.
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2005: Siepka Sandra M; Takahashi Joseph S
Forward genetic screens to identify circadian rhythm mutants in mice.
Methods in enzymology 2005;393():219-29.
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2004: Welsh David K; Yoo Seung-Hee; Liu Andrew C; Takahashi Joseph S; Kay Steve A
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression.
Current biology : CB 2004;14(24):2289-95.
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2004: Triqueneaux Gérard; Thenot Sandrine; Kakizawa Tomoko; Antoch Marina P; Safi Rachid; Takahashi Joseph S; Delaunay Franck; Laudet Vincent
The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.
Journal of molecular endocrinology 2004;33(3):585-608.
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2004: Goldowitz Dan; Frankel Wayne N; Takahashi Joseph S; Holtz-Vitaterna Martha; Bult Carol; Kibbe Warren A; Snoddy Jay; Li Yanxia; Pretel Stephanie; Yates Jeana; Swanson Douglas J
Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function.
Brain research. Molecular brain research 2004;132(2):105-15.
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2004: Pinto Lawrence H; Vitaterna Martha Hotz; Siepka Sanda M; Shimomura Kazuhiro; Lumayag Stephen; Baker Matthew; Fenner Deborah; Mullins Robert F; Sheffield Val C; Stone Edwin M; Heffron Edward; Takahashi Joseph S
Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus.
Vision research 2004;44(28):3335-45.
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2004: Takahashi Joseph S
Finding new clock components: past and future.
Journal of biological rhythms 2004;19(5):339-47.
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2004: Clark Amander T; Goldowitz Daniel; Takahashi Joseph S; Vitaterna Martha Hotz; Siepka Sandra M; Peters Luanne L; Frankel Wayne N; Carlson George A; Rossant Janet; Nadeau Joseph H; Justice Monica J
Implementing large-scale ENU mutagenesis screens in North America.
Genetica 2004;122(1):51-64.
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2004: Miller Brooke H; Olson Susan Losee; Turek Fred W; Levine Jon E; Horton Teresa H; Takahashi Joseph S
Circadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy.
Current biology : CB 2004;14(15):1367-73.
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2004: Bult Carol; Kibbe Warren A; Snoddy Jay; Vitaterna Martha; Swanson Doug; Pretel Stephanie; Li Yanxia; Hohman Moses M; Rinchik Eugene; Takahashi Joe S; Frankel Wayne N; Goldowitz Dan
A genome end-game: understanding gene function in the nervous system.
Nature neuroscience 2004;7(5):484-5.
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2004: Kolker Daniel E; Vitaterna Martha Hotz; Fruechte Ethan M; Takahashi Joseph S; Turek Fred W
Effects of age on circadian rhythms are similar in wild-type and heterozygous Clock mutant mice.
Neurobiology of aging 2004;25(4):517-23.
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2004: Yoo Seung-Hee; Yamazaki Shin; Lowrey Phillip L; Shimomura Kazuhiro; Ko Caroline H; Buhr Ethan D; Siepka Sandra M; Hong Hee-Kyung; Oh Won Jun; Yoo Ook Joon; Menaker Michael; Takahashi Joseph S
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5339-46.
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2004: Hong Hee-Kyung; Chakravarti Aravinda; Takahashi Joseph S
The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1748-53.
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2004: Lowrey Phillip L; Takahashi Joseph S
Mammalian circadian biology: elucidating genome-wide levels of temporal organization.
Annual review of genomics and human genetics 2004;5():407-41.
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2003: Kolker Daniel E; Fukuyama Hiroo; Huang David S; Takahashi Joseph S; Horton Teresa H; Turek Fred W
Aging alters circadian and light-induced expression of clock genes in golden hamsters.
Journal of biological rhythms 2003;18(2):159-69.
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2003: Zambon Alexander C; McDearmon Erin L; Salomonis Nathan; Vranizan Karen M; Johansen Kirsten L; Adey Deborah; Takahashi Joseph S; Schambelan Morris; Conklin Bruce R
Time- and exercise-dependent gene regulation in human skeletal muscle.
Genome biology 2003;4(10):R61.
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2002: Panda Satchidananda; Antoch Marina P; Miller Brooke H; Su Andrew I; Schook Andrew B; Straume Marty; Schultz Peter G; Kay Steve A; Takahashi Joseph S; Hogenesch John B
Coordinated transcription of key pathways in the mouse by the circadian clock.
Cell 2002;109(3):307-20.
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2002: Wilsbacher Lisa D; Yamazaki Shin; Herzog Erik D; Song Eun-Joo; Radcliffe Laurel A; Abe Michikazu; Block Gene; Spitznagel Edward; Menaker Michael; Takahashi Joseph S
Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice invivo.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):489-94.
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2001: Reid K J; Chang A M; Dubocovich M L; Turek F W; Takahashi J S; Zee P C
Familial advanced sleep phase syndrome.
Archives of neurology 2001;58(7):1089-94.
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2001: Shimomura K; Low-Zeddies S S; King D P; Steeves T D; Whiteley A; Kushla J; Zemenides P D; Lin A; Vitaterna M H; Churchill G A; Takahashi J S
Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice.
Genome research 2001;11(6):959-80.
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2001: Low-Zeddies S S; Takahashi J S
Chimera analysis of the Clock mutation in mice shows that complex cellular integration determines circadian behavior.
Cell 2001;105(1):25-42.
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2001: Vitaterna M H; Takahashi J S; Turek F W
Overview of circadian rhythms.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2001;25(2):85-93.
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2000: Bunger M K; Wilsbacher L D; Moran S M; Clendenin C; Radcliffe L A; Hogenesch J B; Simon M C; Takahashi J S; Bradfield C A
Mop3 is an essential component of the master circadian pacemaker in mammals.
Cell 2000;103(7):1009-17.
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2000: Wilsbacher L D; Sangoram A M; Antoch M P; Takahashi J S
The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5.
Genome research 2000;10(12):1928-40.
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2000: Naylor E; Bergmann B M; Krauski K; Zee P C; Takahashi J S; Vitaterna M H; Turek F W
The circadian clock mutation alters sleep homeostasis in the mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):8138-43.
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2000: Hogenesch J B; Gu Y Z; Moran S M; Shimomura K; Radcliffe L A; Takahashi J S; Bradfield C A
The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(13):RC83.
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2000: Valentinuzzi V S; Buxton O M; Chang A M; Scarbrough K; Ferrari E A; Takahashi J S; Turek F W
Locomotor response to an open field during C57BL/6J active and inactive phases: differences dependent on conditions of illumination.
Physiology & behavior 2000;69(3):269-75.
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2000: Lowrey P L; Shimomura K; Antoch M P; Yamazaki S; Zemenides P D; Ralph M R; Menaker M; Takahashi J S
Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.
Science (New York, N.Y.) 2000;288(5465):483-92.
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2000: Challet E; Takahashi J S; Turek F W
Nonphotic phase-shifting in clock mutant mice.
Brain research 2000;859(2):398-403.
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2000: Zhu H; LaRue S; Whiteley A; Steeves T D; Takahashi J S; Green C B
The Xenopus clock gene is constitutively expressed in retinal photoreceptors.
Brain research. Molecular brain research 2000;75(2):303-8.
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2000: Lowrey P L; Takahashi J S
Genetics of the mammalian circadian system: Photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation.
Annual review of genetics 2000;34():533-562.
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1999: Vitaterna M H; Selby C P; Todo T; Niwa H; Thompson C; Fruechte E M; Hitomi K; Thresher R J; Ishikawa T; Miyazaki J; Takahashi J S; Sancar A
Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12114-9.
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1999: Takahashi J S
Narcolepsy genes wake up the sleep field.
Science (New York, N.Y.) 1999;285(5436):2076-7.
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1999: Hahm S; Mizuno T M; Wu T J; Wisor J P; Priest C A; Kozak C A; Boozer C N; Peng B; McEvoy R C; Good P; Kelley K A; Takahashi J S; Pintar J E; Roberts J L; Mobbs C V; Salton S R
Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance.
Neuron 1999;23(3):537-48.
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1999: Steeves T D; King D P; Zhao Y; Sangoram A M; Du F; Bowcock A M; Moore R Y; Takahashi J S
Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei.
Genomics 1999;57(2):189-200.
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1998: Herzog E D; Takahashi J S; Block G D
Clock controls circadian period in isolated suprachiasmatic nucleus neurons.
Nature neuroscience 1998;1(8):708-13.
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1998: Zhang Y; Brainard G C; Zee P C; Pinto L H; Takahashi J S; Turek F W
Effects of aging on lens transmittance and retinal input to the suprachiasmatic nucleus in golden hamsters.
Neuroscience letters 1998;258(3):167-70.
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1998: Nikaido S S; Takahashi J S
Day/night differences in the stimulation of adenylate cyclase activity by calcium/calmodulin in chick pineal cell cultures: evidence for circadian regulation of cyclic AMP.
Journal of biological rhythms 1998;13(6):479-93.
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1998: Sangoram A M; Saez L; Antoch M P; Gekakis N; Staknis D; Whiteley A; Fruechte E M; Vitaterna M H; Shimomura K; King D P; Young M W; Weitz C J; Takahashi J S
Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.
Neuron 1998;21(5):1101-13.
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1998: Thresher R J; Vitaterna M H; Miyamoto Y; Kazantsev A; Hsu D S; Petit C; Selby C P; Dawut L; Smithies O; Takahashi J S; Sancar A
Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
Science (New York, N.Y.) 1998;282(5393):1490-4.
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1998: Wilsbacher L D; Takahashi J S
Circadian rhythms: molecular basis of the clock.
Current opinion in genetics & development 1998;8(5):595-602.
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1998: Max M; Surya A; Takahashi J S; Margolskee R F; Knox B E
Light-dependent activation of rod transducin by pineal opsin.
The Journal of biological chemistry 1998;273(41):26820-6.
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1998: Valentinuzzi V S; Kolker D E; Vitaterna M H; Shimomura K; Whiteley A; Low-Zeddies S; Turek F W; Ferrari E A; Paylor R; Takahashi J S
Automated measurement of mouse freezing behavior and its use for quantitative trait locus analysis of contextual fear conditioning in (BALB/cJ x C57BL/6J)F2 mice.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):391-403.
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1998: Shimomura K; Kornhauser J M; Wisor J P; Umezu T; Yamazaki S; Ihara N L; Takahashi J S; Menaker M
Circadian behavior and plasticity of light-induced c-fos expression in SCN of tau mutant hamsters.
Journal of biological rhythms 1998;13(4):305-14.
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1998: Darlington T K; Wager-Smith K; Ceriani M F; Staknis D; Gekakis N; Steeves T D; Weitz C J; Takahashi J S; Kay S A
Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.
Science (New York, N.Y.) 1998;280(5369):1599-603.
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1998: Gekakis N; Staknis D; Nguyen H B; Davis F C; Wilsbacher L D; King D P; Takahashi J S; Weitz C J
Role of the CLOCK protein in the mammalian circadian mechanism.
Science (New York, N.Y.) 1998;280(5369):1564-9.
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1997: Valentinuzzi V S; Scarbrough K; Takahashi J S; Turek F W
Effects of aging on the circadian rhythm of wheel-running activity in C57BL/6 mice.
The American journal of physiology 1997;273(6 Pt 2):R1957-64.
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1997: Barrett R K; Takahashi J S
Lability of circadian pacemaker amplitude in chick pineal cells: a temperature-dependent process.
Journal of biological rhythms 1997;12(4):309-18.
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1997: King D P; Vitaterna M H; Chang A M; Dove W F; Pinto L H; Turek F W; Takahashi J S
The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.
Genetics 1997;146(3):1049-60.
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1997: Lin J T; Kornhauser J M; Singh N P; Mayo K E; Takahashi J S
Visual sensitivities of nur77 (NGFI-B) and zif268 (NGFI-A) induction in the suprachiasmatic nucleus are dissociated from c-fos induction and behavioral phase-shifting responses.
Brain research. Molecular brain research 1997;46(1-2):303-10.
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1997: Antoch M P; Song E J; Chang A M; Vitaterna M H; Zhao Y; Wilsbacher L D; Sangoram A M; King D P; Pinto L H; Takahashi J S
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
Cell 1997;89(4):655-67.
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1997: King D P; Zhao Y; Sangoram A M; Wilsbacher L D; Tanaka M; Antoch M P; Steeves T D; Vitaterna M H; Kornhauser J M; Lowrey P L; Turek F W; Takahashi J S
Positional cloning of the mouse circadian clock gene.
Cell 1997;89(4):641-53.
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1997: Wisor J P; Takahashi J S
Regulation of the vgf gene in the golden hamster suprachiasmatic nucleus by light and by the circadian clock.
The Journal of comparative neurology 1997;378(2):229-38.
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1996: Zhang Y; Takahashi J S; Turek F W
Critical period for cycloheximide blockade of light-induced phase advances of the circadian locomotor activity rhythm in golden hamsters.
Brain research 1996;740(1-2):285-90.
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1996: Florez J C; Seidenman K J; Barrett R K; Sangoram A M; Takahashi J S
Molecular cloning of chick pineal tryptophan hydroxylase and circadian oscillation of its mRNA levels.
Brain research. Molecular brain research 1996;42(1):25-30.
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1996: Florez J C; Takahashi J S
Quantitative two-dimensional gel electrophoretic analysis of clock-controlled proteins in cultured chick pineal cells: circadian regulation of tryptophan hydroxylase.
Journal of biological rhythms 1996;11(3):241-57.
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1996: Florez J C; Takahashi J S
Regulation of tryptophan hydroxylase by cyclic AMP, calcium, norepinephrine, and light in cultured chick pineal cells.
Journal of neurochemistry 1996;67(1):242-50.
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1996: Kornhauser J M; Mayo K E; Takahashi J S
Light, immediate-early genes, and circadian rhythms.
Behavior genetics 1996;26(3):221-40.
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1996: Nikaido S S; Takahashi J S
Calcium modulates circadian variation in cAMP-stimulated melatonin in chick pineal cells.
Brain research 1996;716(1-2):1-10.
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1996: Zhang Y; Kornhauser J M; Zee P C; Mayo K E; Takahashi J S; Turek F W
Effects of aging on light-induced phase-shifting of circadian behavioral rhythms, fos expression and CREB phosphorylation in the hamster suprachiasmatic nucleus.
Neuroscience 1996;70(4):951-61.
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1996: King D P; Takahashi J S
Forward genetic approaches to circadian clocks in mice.
Cold Spring Harbor symposia on quantitative biology 1996;61():295-302.
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1996: Kornhauser J M; Ginty D D; Greenberg M E; Mayo K E; Takahashi J S
Light entrainment and activation of signal transduction pathways in the SCN.
Progress in brain research 1996;111():133-46.
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1996: Takahashi J S
The biological clock: it's all in the genes.
Progress in brain research 1996;111():5-9.
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1995: Florez J C; Takahashi J S
The circadian clock: from molecules to behaviour.
Annals of medicine 1995;27(4):481-90.
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1995: Barrett R K; Takahashi J S
Temperature compensation and temperature entrainment of the chick pineal cell circadian clock.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(8):5681-92.
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1995: Turek F W; Pinto L H; Vitaterna M H; Penev P D; Zee P C; Takahashi J S
Pharmacological and genetic approaches for the study of circadian rhythms in mammals.
Frontiers in neuroendocrinology 1995;16(3):191-223.
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1995: Max M; McKinnon P J; Seidenman K J; Barrett R K; Applebury M L; Takahashi J S; Margolskee R F
Pineal opsin: a nonvisual opsin expressed in chick pineal.
Science (New York, N.Y.) 1995;267(5203):1502-6.
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1995: Janavs J L; Florez J C; Pierce M E; Takahashi J S
Forskolin and camptothecin induce a 30 kDa protein associated with melatonin production in Y79 human retinoblastoma cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(1 Pt 1):298-309.
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1995: Turek F W; Penev P; Zhang Y; Van Reeth O; Takahashi J S; Zee P
Alterations in the circadian system in advanced age.
Ciba Foundation symposium 1995;183():212-26; discussion 226-34.
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1995: Takahashi J S
Molecular neurobiology and genetics of circadian rhythms in mammals.
Annual review of neuroscience 1995;18():531-53.
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1994: Besecke L M; Wolfe A M; Pierce M E; Takahashi J S; Levine J E
Neuropeptide Y stimulates luteinizing hormone-releasing hormone release from superfused hypothalamic GT1-7 cells.
Endocrinology 1994;135(4):1621-7.
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1994: Sheshberadaran H; Takahashi J S
Characterization of the chicken rhodopsin promoter: identification of retina-specific and glass-like protein binding domains.
Molecular and cellular neurosciences 1994;5(4):309-18.
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1994: Takahashi J S; Pinto L H; Vitaterna M H
Forward and reverse genetic approaches to behavior in the mouse.
Science (New York, N.Y.) 1994;264(5166):1724-33.
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1994: Vitaterna M H; King D P; Chang A M; Kornhauser J M; Lowrey P L; McDonald J D; Dove W F; Pinto L H; Turek F W; Takahashi J S
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior.
Science (New York, N.Y.) 1994;264(5159):719-25.
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1994: Janavs J L; Pierce M E; Takahashi J S
RNA synthesis inhibitors increase melatonin production in Y79 human retinoblastoma cells.
Brain research. Molecular brain research 1994;23(1-2):47-56.
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1994: Takahashi J S
Circadian rhythms. ICER is nicer at night (sir!).
Current biology : CB 1994;4(2):165-8.
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1993: Zhang Y; Van Reeth O; Zee P C; Takahashi J S; Turek F W
Fos protein expression in the circadian clock is not associated with phase shifts induced by a nonphotic stimulus, triazolam.
Neuroscience letters 1993;164(1-2):203-8.
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1993: Zhang Y; Zee P C; Kirby J D; Takahashi J S; Turek F W
A cholinergic antagonist, mecamylamine, blocks light-induced fos immunoreactivity in specific regions of the hamster suprachiasmatic nucleus.
Brain research 1993;615(1):107-12.
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1993: Takahashi J S
Circadian-clock regulation of gene expression.
Current opinion in genetics & development 1993;3(2):301-9.
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1993: Pierce M E; Sheshberadaran H; Zhang Z; Fox L E; Applebury M L; Takahashi J S
Circadian regulation of iodopsin gene expression in embryonic photoreceptors in retinal cell culture.
Neuron 1993;10(4):579-84.
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1993: Ginty D D; Kornhauser J M; Thompson M A; Bading H; Mayo K E; Takahashi J S; Greenberg M E
Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock.
Science (New York, N.Y.) 1993;260(5105):238-41.
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1993: Takahashi J S; Kornhauser J M; Koumenis C; Eskin A
Molecular approaches to understanding circadian oscillations.
Annual review of physiology 1993;55():729-53.
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1992: Takahashi J S
Circadian clock genes are ticking.
Science (New York, N.Y.) 1992;258(5080):238-40.
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1992: Smith R D; Turek F W; Takahashi J S
Two families of phase-response curves characterize the resetting of the hamster circadian clock.
The American journal of physiology 1992;262(6 Pt 2):R1149-53.
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1992: Kornhauser J M; Nelson D E; Mayo K E; Takahashi J S
Regulation of jun-B messenger RNA and AP-1 activity by light and a circadian clock.
Science (New York, N.Y.) 1992;255(5051):1581-4.
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1991: Nelson D E; Takahashi J S
Comparison of visual sensitivity for suppression of pineal melatonin and circadian phase-shifting in the golden hamster.
Brain research 1991;554(1-2):272-7.
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1991: Janavs J L; Pierce M E; Takahashi J S
N-acetyltransferase and protein synthesis modulate melatonin production by Y79 human retinoblastoma cells.
Brain research 1991;540(1-2):138-44.
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1990: Kornhauser J M; Nelson D E; Mayo K E; Takahashi J S
Photic and circadian regulation of c-fos gene expression in the hamster suprachiasmatic nucleus.
Neuron 1990;5(2):127-34.
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1990: Milette J J; Takahashi J S; Turek F W
Photic threshold for stimulation of testicular growth and pituitary FSH release in male Djungarian hamsters.
Brain research 1990;512(2):304-8.
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1989: Nikaido S S; Takahashi J S
Twenty-four hour oscillation of cAMP in chick pineal cells: role of cAMP in the acute and circadian regulation of melatonin production.
Neuron 1989;3(5):609-19.
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1989: Pratt B L; Takahashi J S
Vasoactive intestinal polypeptide and alpha 2-adrenoceptor agonists regulate adenosine 3',5'-monophosphate accumulation and melatonin release in chick pineal cell cultures.
Endocrinology 1989;125(5):2375-84.
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1989: Wollnik F; Turek F W; Majewski P; Takahashi J S
Phase shifting the circadian clock with cycloheximide: response of hamsters with an intact or a split rhythm of locomotor activity.
Brain research 1989;496(1-2):82-8.
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1989: Pierce M E; Barker D; Harrington J; Takahashi J S
Cyclic AMP-dependent melatonin production in Y79 human retinoblastoma cells.
Journal of neurochemistry 1989;53(1):307-10.
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1989: Takahashi J S; Nelson D E; Eskin A
Immunocytochemical localization of serotonergic fibers innervating the ocular circadian system of Aplysia.
Neuroscience 1989;28(1):139-47.
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1989: Takahashi J S; Murakami N; Nikaido S S; Pratt B L; Robertson L M
The avian pineal, a vertebrate model system of the circadian oscillator: cellular regulation of circadian rhythms by light, second messengers, and macromolecular synthesis.
Recent progress in hormone research 1989;45():279-348; discussion 348-52.
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1988: Inouye S T; Takahashi J S; Wollnik F; Turek F W
Inhibitor of protein synthesis phase shifts a circadian pacemaker in mammalian SCN.
The American journal of physiology 1988;255(6 Pt 2):R1055-8.
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1988: Pratt B L; Takahashi J S
A pertussis toxin-sensitive G-protein mediates the alpha 2-adrenergic receptor inhibition of melatonin release in photoreceptive chick pineal cell cultures.
Endocrinology 1988;123(1):277-83.
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1988: Robertson L M; Takahashi J S
Circadian clock in cell culture: II. In vitro photic entrainment of melatonin oscillation from dissociated chick pineal cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(1):22-30.
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1988: Robertson L M; Takahashi J S
Circadian clock in cell culture: I. Oscillation of melatonin release from dissociated chick pineal cells in flow-through microcarrier culture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(1):12-21.
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1987: Pratt B L; Takahashi J S
Alpha-2 adrenergic regulation of melatonin release in chick pineal cell cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(11):3665-74.
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