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Masahide Takahashi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Jiang Ping; Enomoto Atsushi; Takahashi Masahide
Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton.
Tsukamoto Hirohisa; Kato Takuya; Enomoto Atsushi; Nakamura Nobuhisa; Shimono Yohei; Jijiwa Mayumi; Asai Naoya; Murakumo Yoshiki; Shibata Kiyosumi; Kikkawa Fumitaka; Takahashi Masahide
Expression of Ret finger protein correlates with outcomes in endometrial cancer.
Enomoto Atsushi; Asai Naoya; Namba Takashi; Wang Yun; Kato Takuya; Tanaka Motoki; Tatsumi Hitoshi; Taya Shinichiro; Tsuboi Daisuke; Kuroda Keisuke; Kaneko Naoko; Sawamoto Kazunobu; Miyamoto Rieko; Jijiwa Mayumi; Murakumo Yoshiki; Sokabe Masahiro; Seki Tatsunori; Kaibuchi Kozo; Takahashi Masahide
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

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All Publications

2009: Jiang Ping; Enomoto Atsushi; Takahashi Masahide
Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton.
Cancer letters 2009;284(2):122-30.
2009: Tsukamoto Hirohisa; Kato Takuya; Enomoto Atsushi; Nakamura Nobuhisa; Shimono Yohei; Jijiwa Mayumi; Asai Naoya; Murakumo Yoshiki; Shibata Kiyosumi; Kikkawa Fumitaka; Takahashi Masahide
Expression of Ret finger protein correlates with outcomes in endometrial cancer.
Cancer science 2009;100(10):1895-901.
2009: Enomoto Atsushi; Asai Naoya; Namba Takashi; Wang Yun; Kato Takuya; Tanaka Motoki; Tatsumi Hitoshi; Taya Shinichiro; Tsuboi Daisuke; Kuroda Keisuke; Kaneko Naoko; Sawamoto Kazunobu; Miyamoto Rieko; Jijiwa Mayumi; Murakumo Yoshiki; Sokabe Masahiro; Seki Tatsunori; Kaibuchi Kozo; Takahashi Masahide
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.
Neuron 2009;63(6):774-87.
2009: Nakamura Nobuhisa; Naruse Keiko; Matsuki Takashi; Hamada Yoji; Nakashima Eitaro; Kamiya Hideki; Matsubara Tatsuaki; Enomoto Atsushi; Takahashi Masahide; Oiso Yutaka; Nakamura Jiro
Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1.
FEBS letters 2009;583(15):2457-63.
2009: Muteliefu Gulinuer; Enomoto Atsushi; Jiang Ping; Takahashi Masahide; Niwa Toshimitsu
Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(7):2051-8.
2009: Kato Takuya; Shimono Yohei; Hasegawa Masaki; Jijiwa Mayumi; Enomoto Atsushi; Asai Naoya; Murakumo Yoshiki; Takahashi Masahide
Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.
Cancer research 2009;69(8):3597-604.
2008: Hagiwara Sumitaka; Murakumo Yoshiki; Sato Tomoko; Shigetomi Toshio; Mitsudo Kenji; Tohnai Iwai; Ueda Minoru; Takahashi Masahide
Up-regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity.
Cancer science 2008;99(10):1916-23.
2008: Hasegawa T; Enomoto A; Kato T; Kawai K; Miyamoto R; Jijiwa M; Ichihara M; Ishida M; Asai N; Murakumo Y; Ohara K; Niwa Y; Goto H; Takahashi M
Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice.
Oncogene 2008;27(43):5684-95.
2008: Hasegawa Masaki; Moritani Suzuko; Murakumo Yoshiki; Sato Tomoko; Hagiwara Sumitaka; Suzuki Chikage; Mii Shinji; Jijiwa Mayumi; Enomoto Atsushi; Asai Naoya; Ichihara Shu; Takahashi Masahide
CD109 expression in basal-like breast carcinoma.
Pathology international 2008;58(5):288-94.
2008: Jijiwa Mayumi; Kawai Kumi; Fukihara Jun; Nakamura Akari; Hasegawa Masaki; Suzuki Chikage; Sato Tomoko; Enomoto Atsushi; Asai Naoya; Murakumo Yoshiki; Takahashi Masahide
GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(4):365-74.
2008: Jiang Ping; Enomoto Atsushi; Jijiwa Mayumi; Kato Takuya; Hasegawa Taisaku; Ishida Maki; Sato Tomoko; Asai Naoya; Murakumo Yoshiki; Takahashi Masahide
An actin-binding protein Girdin regulates the motility of breast cancer cells.
Cancer research 2008;68(5):1310-8.
2008: Kitamura Tomoya; Asai Naoya; Enomoto Atsushi; Maeda Kengo; Kato Takuya; Ishida Maki; Jiang Ping; Watanabe Takashi; Usukura Jiro; Kondo Takahisa; Costantini Frank; Murohara Toyoaki; Takahashi Masahide
Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.
Nature cell biology 2008;10(3):329-37.
2008: Suzuki Chikage; Murakumo Yoshiki; Kawase Yukari; Sato Tomoko; Morinaga Takatoshi; Fukuda Naoyuki; Enomoto Atsushi; Ichihara Masatoshi; Takahashi Masahide
A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.
Biochemical and biophysical research communications 2008;366(1):226-32.
2007: Sato Tomoko; Murakumo Yoshiki; Hagiwara Sumitaka; Jijiwa Mayumi; Suzuki Chikage; Yatabe Yasushi; Takahashi Masahide
High-level expression of CD109 is frequently detected in lung squamous cell carcinomas.
Pathology international 2007;57(11):719-24.
2007: Dambara Atsushi; Morinaga Takatoshi; Fukuda Naoyuki; Yamakawa Yoshinori; Kato Takuya; Enomoto Atsushi; Asai Naoya; Murakumo Yoshiki; Matsuo Seiichi; Takahashi Masahide
Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation.
Experimental cell research 2007;313(17):3755-66.
2007: Murakami Masashi; Ichihara Masatoshi; Sobue Sayaka; Kikuchi Ryosuke; Ito Hiromi; Kimura Ami; Iwasaki Takashi; Takagi Akira; Kojima Tetsuhito; Takahashi Masahide; Suzuki Motoshi; Banno Yoshiko; Nozawa Yoshinori; Murate Takashi
RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis.
Journal of neurochemistry 2007;102(5):1585-94.
2007: Ishida Maki; Ichihara Masatoshi; Mii Shinji; Jijiwa Mayumi; Asai Naoya; Enomoto Atsushi; Kato Takuya; Majima Ai; Ping Jiang; Murakumo Yoshiki; Takahashi Masahide
Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase.
Cancer science 2007;98(6):815-21.
2007: Hasegawa Masaki; Hagiwara Sumitaka; Sato Tomoko; Jijiwa Mayumi; Murakumo Yoshiki; Maeda Masahiro; Moritani Suzuko; Ichihara Shu; Takahashi Masahide
CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells.
Pathology international 2007;57(5):245-50.
2007: Ichihara Masatoshi; Murakumo Yoshiki; Masuda Akio; Matsuura Toru; Asai Naoya; Jijiwa Mayumi; Ishida Maki; Shinmi Jun; Yatsuya Hiroshi; Qiao Shanlou; Takahashi Masahide; Ohno Kinji
Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities.
Nucleic acids research 2007;35(18):e123.
2006: Enomoto Atsushi; Ping Jiang; Takahashi Masahide
Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways.
Annals of the New York Academy of Sciences 2006;1086():169-84.
2006: Asai Naoya; Fukuda Toshifumi; Wu Zaiqi; Enomoto Atsushi; Pachnis Vassilis; Takahashi Masahide; Costantini Frank
Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Development (Cambridge, England) 2006;133(22):4507-16.
2006: Uchida Mayumi; Enomoto Atsushi; Fukuda Toshifumi; Kurokawa Kei; Maeda Kengo; Kodama Yoshinori; Asai Naoya; Hasegawa Taisaku; Shimono Yohei; Jijiwa Mayumi; Ichihara Masatoshi; Murakumo Yoshiki; Takahashi Masahide
Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase.
Journal of cell science 2006;119(Pt 15):3067-77.
2006: Asai Naoya; Jijiwa Mayumi; Enomoto Atsushi; Kawai Kumi; Maeda Kengo; Ichiahara Masatoshi; Murakumo Yoshiki; Takahashi Masahide
RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.
Pathology international 2006;56(4):164-72.
2006: Murakumo Yoshiki; Mizutani Sachie; Yamaguchi Mariko; Ichihara Masatoshi; Takahashi Masahide
Analyses of ultraviolet-induced focus formation of hREV1 protein.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(3):193-205.
2006: Takeda Kozue; Kawamoto Yoshiyuki; Okuno Yusuke; Kato Masashi; Takahashi Masahide; Suzuki Haruhiko; Isobe Kenichi; Nakashima Izumi
A PKC-mediated backup mechanism of the MXXCW motif-linked switch for initiating tyrosine kinase activities.
FEBS letters 2006;580(3):839-43.
2006: Murakumo Yoshiki; Jijiwa Mayumi; Asai Naoya; Ichihara Masatoshi; Takahashi Masahide
RET and neuroendocrine tumors.
Pituitary 2006;9(3):179-92.
2005: Shimono Keiko; Shimono Yohei; Shimokata Kaoru; Ishiguro Naoki; Takahashi Masahide
Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription.
The Journal of biological chemistry 2005;280(47):39436-47.
2005: Enomoto Atsushi; Murakami Hideki; Asai Naoya; Morone Nobuhiro; Watanabe Takashi; Kawai Kumi; Murakumo Yoshiki; Usukura Jiro; Kaibuchi Kozo; Takahashi Masahide
Akt/PKB regulates actin organization and cell motility via Girdin/APE.
Developmental cell 2005;9(3):389-402.
2005: Matsuura Tetsuo; Shimono Yohei; Kawai Kumi; Murakami Hideki; Urano Takeshi; Niwa Yasumasa; Goto Hidemi; Takahashi Masahide
PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.
Experimental cell research 2005;308(1):65-77.
2005: Fukuda Toshifumi; Asai Naoya; Enomoto Atsushi; Takahashi Masahide
Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(7):655-63.
2005: Zhang Jing-Min; Hashimoto Mizuo; Kawai Kumi; Murakumo Yoshiki; Sato Tomoko; Ichihara Masatoshi; Nakamura Shigeo; Takahashi Masahide
CD109 expression in squamous cell carcinoma of the uterine cervix.
Pathology international 2005;55(4):165-9.
2005: Kodama Yoshinori; Asai Naoya; Kawai Kumi; Jijiwa Mayumi; Murakumo Yoshiki; Ichihara Masatoshi; Takahashi Masahide
The RET proto-oncogene: a molecular therapeutic target in thyroid cancer.
Cancer science 2005;96(3):143-8.
2005: Morinaga Takatoshi; Enomoto Atsushi; Shimono Yohei; Hirose Fumiko; Fukuda Naoyuki; Dambara Atsushi; Jijiwa Mayumi; Kawai Kumi; Hashimoto Katsunori; Ichihara Masatoshi; Asai Naoya; Murakumo Yoshiki; Matsuo Seiichi; Takahashi Masahide
GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region.
Nucleic acids research 2005;33(13):4191-201.
2004: Matsushita Tadashi; Hayashi Hideo; Kunishima Shinji; Hayashi Mutsuharu; Ikejiri Makoto; Takeshita Kyosuke; Yuzawa Yukio; Adachi Tatsuya; Hirashima Kanji; Sone Michihiko; Yamamoto Koji; Takagi Akira; Katsumi Akira; Kawai Kumi; Nezu Tomoyo; Takahashi Masahide; Nakashima Tsutomu; Naoe Tomoki; Kojima Tetsuhito; Saito Hidehiko
Targeted disruption of mouse ortholog of the human MYH9 responsible for macrothrombocytopenia with different organ involvement: hematological, nephrological, and otological studies of heterozygous KO mice.
Biochemical and biophysical research communications 2004;325(4):1163-71.
2004: Jin Yi; Murakumo Yoshiki; Ueno Kaoru; Hashimoto Mizuo; Watanabe Tsuyoshi; Shimoyama Yoshie; Ichihara Masatoshi; Takahashi Masahide
Identification of a mouse cytoskeleton-associated protein, CKAP2, with microtubule-stabilizing properties.
Cancer science 2004;95(10):815-21.
2004: Maeda Kengo; Murakami Hideki; Yoshida Reiko; Ichihara Masatoshi; Abe Akihiro; Hirai Makoto; Murohara Toyoaki; Takahashi Masahide
Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells.
Biochemical and biophysical research communications 2004;323(1):345-54.
2004: Jijiwa Mayumi; Fukuda Toshifumi; Kawai Kumi; Nakamura Akari; Kurokawa Kei; Murakumo Yoshiki; Ichihara Masatoshi; Takahashi Masahide
A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia.
Molecular and cellular biology 2004;24(18):8026-36.
2004: Abe Akihiro; Emi Nobuhiko; Kanie Tadaharu; Imagama Shizuka; Kuno Yoshie; Takahashi Masahide; Saito Hidehiko; Naoe Tomoki
Expression cloning of oligomerization-activated genes with cell-proliferating potency by pseudotype retrovirus vector.
Biochemical and biophysical research communications 2004;320(3):920-6.
2004: Kodama Yoshinori; Murakumo Yoshiki; Ichihara Masatoshi; Kawai Kumi; Shimono Yohei; Takahashi Masahide
Induction of CRMP-2 by GDNF and analysis of the CRMP-2 promoter region.
Biochemical and biophysical research communications 2004;320(1):108-15.
2004: Hashimoto Mizuo; Ichihara Masatoshi; Watanabe Tsuyoshi; Kawai Kumi; Koshikawa Katsumi; Yuasa Norihiro; Takahashi Takashi; Yatabe Yasushi; Murakumo Yoshiki; Zhang Jing-Min; Nimura Yuji; Takahashi Masahide
Expression of CD109 in human cancer.
Oncogene 2004;23(20):3716-20.
2004: Mori Shoichi; Ito Genshi; Usami Noriyasu; Yoshioka Hiromu; Ueda Yuichi; Kodama Yoshinori; Takahashi Masahide; Fong Kwun M; Shimokata Kaoru; Sekido Yoshitaka
p53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma.
Cancer 2004;100(8):1673-82.
2004: Kawamoto Yoshiyuki; Takeda Kozue; Okuno Yusuke; Yamakawa Yoshinori; Ito Yasutomo; Taguchi Ryo; Kato Masashi; Suzuki Haruhiko; Takahashi Masahide; Nakashima Izumi
Identification of RET autophosphorylation sites by mass spectrometry.
The Journal of biological chemistry 2004;279(14):14213-24.
2004: Ichihara Masatoshi; Murakumo Yoshiki; Takahashi Masahide
RET and neuroendocrine tumors.
Cancer letters 2004;204(2):197-211.
2004: Kato Masashi; Takeda Kozue; Kawamoto Yoshiyuki; Tsuzuki Toyonori; Hossain Khaled; Tamakoshi Akiko; Kunisada Takahiro; Kambayashi Yasuhiro; Ogino Keiki; Suzuki Haruhiko; Takahashi Masahide; Nakashima Izumi
c-Kit-targeting immunotherapy for hereditary melanoma in a mouse model.
Cancer research 2004;64(3):801-6.
2004: Maeda Osamu; Usami Noriyasu; Kondo Masashi; Takahashi Masahide; Goto Hidemi; Shimokata Kaoru; Kusugami Kazuo; Sekido Yoshitaka
Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line.
Oncogene 2004;23(4):964-72.
2003: Uchiyama Mika; Usami Noriyasu; Kondo Masashi; Mori Shoichi; Ito Masao; Ito Genshi; Yoshioka Hiromu; Imaizumi Munehisa; Ueda Yuichi; Takahashi Masahide; Minna John D; Shimokata Kaoru; Sekido Yoshitaka
Loss of heterozygosity of chromosome 12p does not correlate with KRAS mutation in non-small cell lung cancer.
International journal of cancer. Journal international du cancer 2003;107(6):962-9.
2003: Shimono Yohei; Murakami Hideki; Kawai Kumi; Wade Paul A; Shimokata Kaoru; Takahashi Masahide
Mi-2 beta associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities.
The Journal of biological chemistry 2003;278(51):51638-45.
2003: Fukuda Naoyuki; Ichihara Masatoshi; Morinaga Takatoshi; Kawai Kumi; Hayashi Hironori; Murakumo Yoshiki; Matsuo Seiichi; Takahashi Masahide
Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis.
The Journal of biological chemistry 2003;278(50):50386-92.
2003: Kawai Kumi; Jijiwa Mayumi; Shimono Yohei; Kurokawa Kei; Murakumo Yoshiki; Ichihara Masatoshi; Takahashi Masahide
Establishment and characterization of mouse mammary carcinoma cell lines expressing RET with a multiple endocrine neoplasia 2A mutation.
Cancer science 2003;94(11):992-7.
2003: Usami Noriyasu; Sekido Yoshitaka; Maeda Osamu; Yamamoto Kazuhito; Minna John D; Hasegawa Yoshinori; Yoshioka Hiromu; Imaizumi Munehisa; Ueda Yuichi; Takahashi Masahide; Shimokata Kaoru
Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion.
Oncogene 2003;22(39):7923-30.
2003: Kurokawa K; Kawai K; Hashimoto M; Ito Y; Takahashi M
Cell signalling and gene expression mediated by RET tyrosine kinase.
Journal of internal medicine 2003;253(6):627-33.
2003: Nishikawa Mikiko; Murakumo Yoshiki; Imai Tsuneo; Kawai Kumi; Nagaya Masahiro; Funahashi Hiroomi; Nakao Akimasa; Takahashi Masahide
Cys611Ser mutation in RET proto-oncogene in a kindred with medullary thyroid carcinoma and Hirschsprung's disease.
European journal of human genetics : EJHG 2003;11(5):364-8.
2003: Nakayama Atsuo; Murakami Hideki; Maeyama Naomi; Yamashiro Norie; Sakakibara Ayako; Mori Naoyoshi; Takahashi Masahide
Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter.
The Journal of biological chemistry 2003;278(1):233-40.
2003: Shimoyama Y; Morikawa Y; Ichihara M; Kodama Y; Fukuda N; Hayashi H; Morinaga T; Iwashita T; Murakumo Y; Takahashi M
Identification of human SEP1 as a glial cell line-derived neurotrophic factor-inducible protein and its expression in the nervous system.
Neuroscience 2003;121(4):899-906.
2002: Umemura Masayuki; Nishimura Hitoshi; Yajima Toshiki; Wajjwalk Worawid; Matsuguchi Testuya; Takahashi Masahide; Nishiyama Yukihiro; Makino Masahiko; Nagai Yoshiyuki; Yoshikai Yasunobu
Overexpression of interleukin-15 prevents the development of murine retrovirus-induced acquired immunodeficiency syndrome.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1755-63.
2002: Tezel Gaye; Nagasaka Tetsuro; Shimono Yohei; Takahashi Masahide
Differential expression of RET finger protein in testicular germ cell tumors.
Pathology international 2002;52(10):623-7.
2002: Murakami Hideki; Yamamura Yumiko; Shimono Yohei; Kawai Kumi; Kurokawa Kei; Takahashi Masahide
Role of Dok1 in cell signaling mediated by RET tyrosine kinase.
The Journal of biological chemistry 2002;277(36):32781-90.
2002: Watanabe Tsuyoshi; Ichihara Masatoshi; Hashimoto Mizuo; Shimono Keiko; Shimoyama Yoshie; Nagasaka Tetsuro; Murakumo Yoshiki; Murakami Hideki; Sugiura Hideshi; Iwata Hisashi; Ishiguro Naoki; Takahashi Masahide
Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.
The American journal of pathology 2002;161(1):249-56.
2002: Iwahashi Naoko; Murakami Hideki; Nimura Yuji; Takahashi Masahide
Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways.
Biochemical and biophysical research communications 2002;294(3):642-9.
2002: Fukuda Toshifumi; Kiuchi Kazutoshi; Takahashi Masahide
Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase.
The Journal of biological chemistry 2002;277(21):19114-21.
2002: Kato Masashi; Takeda Kozue; Kawamoto Yoshiyuki; Iwashita Toshihide; Akhand Anwarul A; Senga Takeshi; Yamamoto Masahiko; Sobue Gen; Hamaguchi Michinari; Takahashi Masahide; Nakashima Izumi
Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.
Cancer research 2002;62(8):2414-22.
2002: Akhand Anwarul A; Ikeyama Takanari; Akazawa Satoru; Kato Masashi; Hossain Khaled; Takeda Kozue; Suzuki Haruhiko; Takahashi Masahide; Nakashima Izumi
Evidence of both extra- and intracellular cysteine targets of protein modification for activation of RET kinase.
Biochemical and biophysical research communications 2002;292(4):826-31.
2002: Iwahashi Naoko; Nagasaka Tetsuro; Tezel Gaye; Iwashita Toshihide; Asai Naoya; Murakumo Yoshiki; Kiuchi Kazutoshi; Sakata Keita; Nimura Yuji; Takahashi Masahide
Expression of glial cell line-derived neurotrophic factor correlates with perineural invasion of bile duct carcinoma.
Cancer 2002;94(1):167-74.
2002: Tezel Gaye; Shimono Yohei; Murakumo Yoshiki; Kawai Kumi; Fukuda Toshifumi; Iwahashi Naoko; Takahashi Masahide
Role for O-glycosylation of RFP in the interaction with enhancer of polycomb.
Biochemical and biophysical research communications 2002;290(1):409-14.
2001: Takahashi M
The GDNF/RET signaling pathway and human diseases.
Cytokine & growth factor reviews 2001;12(4):361-73.
2001: Kato M; Takeda K; Kawamoto Y; Tsuzuki T; Dai Y; Nakayama S; Toriyama K; Tamada Y; Takahashi M; Nakashima I
RET tyrosine kinase enhances hair growth in association with promotion of melanogenesis.
Oncogene 2001;20(51):7536-41.
2001: Murakumo Y; Ogura Y; Ishii H; Numata S; Ichihara M; Croce C M; Fishel R; Takahashi M
Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7.
The Journal of biological chemistry 2001;276(38):35644-51.
2001: Yamamoto M; Li M; Mitsuma N; Ito S; Kato M; Takahashi M; Sobue G
Preserved phosphorylation of RET receptor protein in spinal motor neurons of patients with amyotrophic lateral sclerosis: an immunohistochemical study by a phosphorylation-specific antibody at tyrosine 1062.
Brain research 2001;912(1):89-94.
2001: Shigemitsu K; Sekido Y; Usami N; Mori S; Sato M; Horio Y; Hasegawa Y; Bader S A; Gazdar A F; Minna J D; Hida T; Yoshioka H; Imaizumi M; Ueda Y; Takahashi M; Shimokata K
Genetic alteration of the beta-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion.
Oncogene 2001;20(31):4249-57.
2001: Iwashita T; Kurokawa K; Qiao S; Murakami H; Asai N; Kawai K; Hashimoto M; Watanabe T; Ichihara M; Takahashi M
Functional analysis of RET with Hirschsprung mutations affecting its kinase domain.
Gastroenterology 2001;121(1):24-33.
2001: Takeda K; Kato M; Wu J; Iwashita T; Suzuki H; Takahashi M; Nakashima I
Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation.
Antioxidants & redox signaling 2001;3(3):473-82.
2001: Kurokawa K; Iwashita T; Murakami H; Hayashi H; Kawai K; Takahashi M
Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.
Oncogene 2001;20(16):1929-38.
2001: Hayashi Y; Iwashita T; Murakamai H; Kato Y; Kawai K; Kurokawa K; Tohnai I; Ueda M; Takahashi M
Activation of BMK1 via tyrosine 1062 in RET by GDNF and MEN2A mutation.
Biochemical and biophysical research communications 2001;281(3):682-9.
2001: Hiki Y; Odani H; Takahashi M; Yasuda Y; Nishimoto A; Iwase H; Shinzato T; Kobayashi Y; Maeda K
Mass spectrometry proves under-O-glycosylation of glomerular IgA1 in IgA nephropathy.
Kidney international 2001;59(3):1077-85.
2001: Qiao S; Iwashita T; Furukawa T; Yamamoto M; Sobue G; Takahashi M
Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins.
The Journal of biological chemistry 2001;276(12):9460-7.
2001: Umemura M; Hirose K; Wajjwaiku W; Nishimura H; Matsuguchi T; Gotoh Y; Takahashi M; Makino M; Yoshikai Y
Impaired IL-15 production associated with susceptibility of murine AIDS to mycobacterial infection.
Journal of leukocyte biology 2001;69(1):138-48.
2000: Shimono Y; Murakami H; Hasegawa Y; Takahashi M
RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions.
The Journal of biological chemistry 2000;275(50):39411-9.
2000: Kawai K; Iwashita T; Murakami H; Hiraiwa N; Yoshiki A; Kusakabe M; Ono K; Iida K; Nakayama A; Takahashi M
Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation.
Cancer research 2000;60(18):5254-60.
2000: Hayashi H; Ichihara M; Iwashita T; Murakami H; Shimono Y; Kawai K; Kurokawa K; Murakumo Y; Imai T; Funahashi H; Nakao A; Takahashi M
Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor.
Oncogene 2000;19(39):4469-75.
2000: Nozaki C; Horibe K; Iwata H; Ishiguro Y; Hamaguchi M; Takahashi M
Prognostic impact of telomerase activity in patients with neuroblastoma.
International journal of oncology 2000;17(2):341-5.
2000: Sato M; Sekido Y; Horio Y; Takahashi M; Saito H; Minna J D; Shimokata K; Hasegawa Y
Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer.
Japanese journal of cancer research : Gann 2000;91(5):504-9.
2000: Odani H; Hiki Y; Takahashi M; Nishimoto A; Yasuda Y; Iwase H; Shinzato T; Maeda K
Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.
Biochemical and biophysical research communications 2000;271(1):268-74.
2000: Iwashita T; Murakami H; Kurokawa K; Kawai K; Miyauchi A; Futami H; Qiao S; Ichihara M; Takahashi M
A two-hit model for development of multiple endocrine neoplasia type 2B by RET mutations.
Biochemical and biophysical research communications 2000;268(3):804-8.
2000: Kato M; Iwashita T; Takeda K; Akhand A A; Liu W; Yoshihara M; Asai N; Suzuki H; Takahashi M; Nakashima I
Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases.
Molecular biology of the cell 2000;11(1):93-101.
2000: Kato M; Iwashita T; Akhand A A; Liu W; Takeda K; Takeuchi K; Yoshihara M; Hossain K; Wu J; Du J; Oh C; Kawamoto Y; Suzuki H; Takahashi M; Nakashima I
Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation.
Antioxidants & redox signaling 2000;2(4):841-9.
1999: Honda T; Yokota S; Gang F G; Takahashi M; Sugiura Y
Evidence for the c-ret protooncogene product (c-Ret) expression in the spinal tanycytes of adult rat.
Journal of chemical neuroanatomy 1999;17(3):163-8.
1999: Honda T; Takahashi M; Sugiura Y
Co-localization of the glial cell-line derived neurotrophic factor and its functional receptor c-RET in a subpopulation of rat dorsal root ganglion neurons.
Neuroscience letters 1999;275(1):45-8.
1999: Tezel G; Nagasaka T; Iwahashi N; Asai N; Iwashita T; Sakata K; Takahashi M
Different nuclear/cytoplasmic distributions of RET finger protein in different cell types.
Pathology international 1999;49(10):881-6.
1999: Okuda T; Matsuda S; Nakatsugawa S; Ichigotani Y; Iwahashi N; Takahashi M; Ishigaki T; Hamaguchi M
Molecular cloning of macrophin, a human homologue of Drosophila kakapo with a close structural similarity to plectin and dystrophin.
Biochemical and biophysical research communications 1999;264(2):568-74.
1999: Funahashi H; Imai T; Tanaka Y; Tsukamura K; Hayakawa Y; Kikumori T; Mase T; Itoh T; Nishikawa M; Hayashi H; Shibata A; Hibi Y; Takahashi M; Narita T
Wakame seaweed suppresses the proliferation of 7,12-dimethylbenz(a)-anthracene-induced mammary tumors in rats.
Japanese journal of cancer research : Gann 1999;90(9):922-7.
1999: Ishiguro Y; Iwashita T; Murakami H; Asai N; Iida K; Goto H; Hayakawa T; Takahashi M
The role of amino acids surrounding tyrosine 1062 in ret in specific binding of the shc phosphotyrosine-binding domain.
Endocrinology 1999;140(9):3992-8.
1999: Murakami H; Iwashita T; Asai N; Shimono Y; Iwata Y; Kawai K; Takahashi M
Enhanced phosphatidylinositol 3-kinase activity and high phosphorylation state of its downstream signalling molecules mediated by ret with the MEN 2B mutation.
Biochemical and biophysical research communications 1999;262(1):68-75.
1999: Katagiri H; Takahashi M; Inagaki J; Sugiura H; Ito S; Iwata H
Determining the site of the primary cancer in patients with skeletal metastasis of unknown origin: a retrospective study.
Cancer 1999;86(3):533-7.
1999: Iwata Y; Nakayama A; Murakami H; Iida K; Iwashita T; Asai N; Takahashi M
Characterization of the promoter region of the human RFP gene.
Biochemical and biophysical research communications 1999;261(2):381-4.
1999: Iwashita T; Kato M; Murakami H; Asai N; Ishiguro Y; Ito S; Iwata Y; Kawai K; Asai M; Kurokawa K; Kajita H; Takahashi M
Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma.
Oncogene 1999;18(26):3919-22.
1999: Murakami H; Iwashita T; Asai N; Iwata Y; Narumiya S; Takahashi M
Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase.
Oncogene 1999;18(11):1975-82.
1999: Asai N; Iwashita T; Murakami H; Takanari H; Ohmori K; Ichihara M; Takahashi M
Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma.
Biochemical and biophysical research communications 1999;255(3):587-90.
1999: Oyabu A; Higo K; Ye C; Amo H; Saito M; Yagyu S; Morita H; Maeda K; Serikawa T; Takahashi M; Matsuyama M
Genetic mapping of the thymoma susceptible locus, Tsr1, in BUF/Mna rats.
Journal of the National Cancer Institute 1999;91(3):279-82.
1999: Mitsuma N; Yamamoto M; Li M; Ito Y; Mitsuma T; Mutoh T; Takahashi M; Sobue G
Expression of GDNF receptor (RET and GDNFR-alpha) mRNAs in the spinal cord of patients with amyotrophic lateral sclerosis.
Brain research 1999;820(1-2):77-85.
1999: Asai M; Kato M; Asai N; Iwashita T; Murakami H; Kawai K; Nakashima I; Takahashi M
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.
Japanese journal of cancer research : Gann 1999;90(1):86-92.
1999: Kato M; Liu W; Akhand A A; Dai Y; Ohbayashi M; Tuzuki T; Suzuki H; Isobe K; Takahashi M; Nakashima I
Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines.
Oncogene 1999;18(3):837-42.
1998: Kato M; Takahashi M; Akhand A A; Liu W; Dai Y; Shimizu S; Iwamoto T; Suzuki H; Nakashima I
Transgenic mouse model for skin malignant melanoma.
Oncogene 1998;17(14):1885-8.
1998: Takahashi M; Asai N; Iwashita T; Murakami H; Ito S
Molecular mechanisms of development of multiple endocrine neoplasia 2 by RET mutations.
Journal of internal medicine 1998;243(6):509-13.
1998: Nozaki C; Asai N; Murakami H; Iwashita T; Iwata Y; Horibe K; Klein R D; Rosenthal A; Takahashi M
Calcium-dependent Ret activation by GDNF and neurturin.
Oncogene 1998;16(3):293-9.
1998: Takahashi M; Asai N; Iwashita T; Murakami H; Ito S
Mechanisms of development of multiple endocrine neoplasia type 2 and Hirschsprung's disease by ret mutations.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():229-36.
1997: Ohiwa M; Murakami H; Iwashita T; Asai N; Iwata Y; Imai T; Funahashi H; Takagi H; Takahashi M
Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations.
Biochemical and biophysical research communications 1997;237(3):747-51.
1997: Sharma N; Ohyabu A; Murakumo Y; Takahashi M; Saito M; Amo H; Murayama S; Ohno K; Oda S; Matsuyama M
Genetic mapping of genes regulating the thymus size in back-cross rats between the laboratory BUF/Mna strain and the MITE strain derived from the wild rat, Rattus norvegicus.
Pathology international 1997;47(7):436-41.
1997: Ito S; Iwashita T; Asai N; Murakami H; Iwata Y; Sobue G; Takahashi M
Biological properties of Ret with cysteine mutations correlate with multiple endocrine neoplasia type 2A, familial medullary thyroid carcinoma, and Hirschsprung's disease phenotype.
Cancer research 1997;57(14):2870-2.
1997: Klein R D; Sherman D; Ho W H; Stone D; Bennett G L; Moffat B; Vandlen R; Simmons L; Gu Q; Hongo J A; Devaux B; Poulsen K; Armanini M; Nozaki C; Asai N; Goddard A; Phillips H; Henderson C E; Takahashi M; Rosenthal A
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.
Nature 1997;387(6634):717-21.
1997: Iwasaki H; Takahashi M; Niimi T; Yamashita O; Yaginuma T
Cloning of cDNAs encoding Bombyx homologues of Cdc2 and Cdc2-related kinase from eggs.
Insect molecular biology 1997;6(2):131-41.
1997: Takahashi M
The role of the ret proto-oncogene in human disease.
Nagoya journal of medical science 1997;60(1-2):23-30.
1997: Watanabe Y; Harada T; Ito T; Ishiguro Y; Ando H; Seo T; Kobayashi S; Takahashi M; Nimura Y
ret Proto-oncogene product is a useful marker of lineage determination in the development of the enteric nervous system in rats.
Journal of pediatric surgery 1997;32(1):28-33.

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