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Motoko Takahashi

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Daisuke Osumi; Motoko Takahashi; Eiji Miyoshi; Shunichi Yokoe; Seung Ho Lee; Katsuhisa Noda; Shoji Nakamori; Jianguo Gu; Yoshitaka Ikeda; Yoshio Kuroki; Kazuo Sengoku; M Ishikawa; Naoyuki Taniguchi
Core fucosylation of E-cadherin enhances cell-cell adhesion in human colon carcinoma WiDr cells.
Yan-Yang Zhao; Motoko Takahashi; Jian-Guo Gu; Eiji Miyoshi; Akio Matsumoto; Shinobu Kitazume; Naoyuki Taniguchi
Functional roles of N-glycans in cell signaling and cell adhesion in cancer.
Yong Seek Park; Jayoung Kim; Yoshiko Misonou; Rina Takamiya; Motoko Takahashi; Michael R Freeman; Naoyuki Taniguchi
Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase.

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All Publications

2009: Daisuke Osumi; Motoko Takahashi; Eiji Miyoshi; Shunichi Yokoe; Seung Ho Lee; Katsuhisa Noda; Shoji Nakamori; Jianguo Gu; Yoshitaka Ikeda; Yoshio Kuroki; Kazuo Sengoku; M Ishikawa; Naoyuki Taniguchi
Core fucosylation of E-cadherin enhances cell-cell adhesion in human colon carcinoma WiDr cells.
Cancer science 2009;100(5):888-95.
2008: Yan-Yang Zhao; Motoko Takahashi; Jian-Guo Gu; Eiji Miyoshi; Akio Matsumoto; Shinobu Kitazume; Naoyuki Taniguchi
Functional roles of N-glycans in cell signaling and cell adhesion in cancer.
Cancer science 2008;99(7):1304-10.
2007: Yong Seek Park; Jayoung Kim; Yoshiko Misonou; Rina Takamiya; Motoko Takahashi; Michael R Freeman; Naoyuki Taniguchi
Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1319-25.
2007: Wei Li; Motoko Takahashi; Yukinao Shibukawa; Shunichi Yokoe; Jianguo Gu; Eiji Miyoshi; Koichi Honke; Yoshitaka Ikeda; Naoyuki Taniguchi
Introduction of bisecting GlcNAc in N-glycans of adenylyl cyclase III enhances its activity.
Glycobiology 2007;17(6):655-62.
2007: Shunichi Yokoe; Motoko Takahashi; Michio Asahi; Seung Ho Lee; Wei Li; Daisuke Osumi; Eiji Miyoshi; Naoyuki Taniguchi
The Asn418-linked N-glycan of ErbB3 plays a crucial role in preventing spontaneous heterodimerization and tumor promotion.
Cancer research 2007;67(5):1935-42.
2006: Susumu Nakahara; Takashi Saito; Nami Kondo; Kenta Moriwaki; Katsuhisa Noda; Shinji Ihara; Motoko Takahashi; Yoshihito Ide; Jianguo Gu; Hidenori Inohara; Taiichi Katayama; Masaya Tohyama; Takeshi Kubo; Naoyuki Taniguchi; Eiji Miyoshi
A secreted type of beta1,6 N-acetylglucosaminyltransferase V (GnT-V), a novel angiogenesis inducer, is regulated by gamma-secretase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(14):2451-9.
2006: Seung Ho Lee; Motoko Takahashi; Koichi Honke; Eiji Miyoshi; Daisuke Osumi; haruhiko sakiyama; Atsuko Ekuni; Wang Xiangchun; Shinya Inoue; Jianguo Gu; Kenji Kadomatsu; Naoyuki Taniguchi
Loss of core fucosylation of low-density lipoprotein receptor-related protein-1 impairs its function, leading to the upregulation of serum levels of insulin-like growth factor-binding protein 3 in Fut8-/- mice.
Journal of biochemistry 2006;139(3):391-8.
2006: haruhiko sakiyama; Motoko Takahashi; Toshihiro Yamamoto; Tadashi Teshima; Seung Ho Lee; Yasuhide Miyamoto; Yoshiko Misonou; Naoyuki Taniguchi
The internalization and metabolism of 3-deoxyglucosone in human umbilical vein endothelial cells.
Journal of biochemistry 2006;139(2):245-53.
2005: Wang Xiangchun; Shinya Inoue; Jianguo Gu; Eiji Miyoshi; Katsuhisa Noda; Wenzhe Li; Yoko Mizuno-Horikawa; Miyako Nakano; Michio Asahi; Motoko Takahashi; Naofumi Uozumi; Shinji Ihara; Seung Ho Lee; Yoshitaka Ikeda; Yukihiro Yamaguchi; Yoshiya Aze; Yoshiaki Tomiyama; Junichi Fujii; Keiichiro Suzuki; Akihiro Kondo; Steven D Shapiro; Carlos Lopez-Otin; Tomoyuki Kuwaki; Masaru Okabe; Koichi Honke; Naoyuki Taniguchi
Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15791-6.
2005: Naoyuki Taniguchi; Motoko Takahashi; haruhiko sakiyama; Yong Seek Park; Michio Asahi; Yoshiko Misonou; Yasuhide Miyamoto
A common pathway for intracellular reactive oxygen species production by glycoxidative and nitroxidative stress in vascular endothelial cells and smooth muscle cells.
Annals of the New York Academy of Sciences 2005;1043():521-8.
2005: Yoshiko Misonou; Motoko Takahashi; Yong Seek Park; Michio Asahi; Yasuhide Miyamoto; haruhiko sakiyama; Xinyao Cheng; Naoyuki Taniguchi
Acrolein induces Hsp72 via both PKCdelta/JNK and calcium signaling pathways in human umbilical vein endothelial cells.
Free radical research 2005;39(5):507-12.
2005: Yong Seek Park; Yoshiko Misonou; Noriko Fujiwara; Motoko Takahashi; Yasuhide Miyamoto; Young Ho Koh; Keiichiro Suzuki; Naoyuki Taniguchi
Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells.
Biochemical and biophysical research communications 2005;327(4):1058-65.
2005: Rina Takamiya; Motoko Takahashi; Yong Seek Park; Yoshie Tawara; Noriko Fujiwara; Yasuhide Miyamoto; Jianguo Gu; Keiichiro Suzuki; Naoyuki Taniguchi
Overexpression of mutated Cu,Zn-SOD in neuroblastoma cells results in cytoskeletal change.
American journal of physiology. Cell physiology 2005;288(2):C253-9.
2004: Tomoya Isaji; Jianguo Gu; Ryoko Nishiuchi; Yanyang Zhao; Motoko Takahashi; Eiji Miyoshi; Koichi Honke; Kiyotoshi Sekiguchi; Naoyuki Taniguchi
Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration.
The Journal of biological chemistry 2004;279(19):19747-54.
2004: Jianguo Gu; Yanyang Zhao; Tomoya Isaji; Yukinao Shibukawa; Hideyuki Ihara; Motoko Takahashi; Yoshitaka Ikeda; Eiji Miyoshi; Koichi Honke; Naoyuki Taniguchi
Beta1,4-N-Acetylglucosaminyltransferase III down-regulates neurite outgrowth induced by costimulation of epidermal growth factor and integrins through the Ras/ERK signaling pathway in PC12 cells.
Glycobiology 2004;14(2):177-86.
2003: Rina Takamiya; Motoko Takahashi; Theingi Myint; Yong Seek Park; Nobuko Miyazawa; Takeshi Endo; Noriko Fujiwara; haruhiko sakiyama; Yoshiko Misonou; Yasuhide Miyamoto; Junichi Fujii; Naoyuki Taniguchi
Glycation proceeds faster in mutated Cu, Zn-superoxide dismutases related to familial amyotrophic lateral sclerosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):938-40.
2003: Yong Seek Park; Young Ho Koh; Motoko Takahashi; Yasuhide Miyamoto; Keiichiro Suzuki; Naoshi Dohmae; Koji Takio; Koichi Honke; Naoyuki Taniguchi
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.
Free radical research 2003;37(2):205-11.
2003: Yukinao Shibukawa; Motoko Takahashi; Isabelle Laffont; Koichi Honke; Naoyuki Taniguchi
Down-regulation of hydrogen peroxide-induced PKC delta activation in N-acetylglucosaminyltransferase III-transfected HeLaS3 cells.
The Journal of biological chemistry 2003;278(5):3197-203.
2002: Isabelle Laffont; Motoko Takahashi; Yukinao Shibukawa; Koichi Honke; Vladimir V Shuvaev; Gérard Siest; Sophie Visvikis; Naoyuki Taniguchi
Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner.
Biochemical and biophysical research communications 2002;292(1):83-7.