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Yoshimi Takai

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Kenji Momose; Kentaro Nobutani; Yohei Shimono; Takeshi Azuma; Akihiro Minami; Kiyohito Mizutani; Yoshimi Takai
miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling.
Kenji Mandai; Yoshiyuki Rikitake; Yohei Shimono; Yoshimi Takai
Afadin/AF-6 and canoe: roles in cell adhesion and beyond.
Min Du; B Brett Finlay; Peter K Nicholls; Calvin D Roskelley; Peter G Stanton; Yoshimi Takai; Jane Cipollone; Marc De Asis; Wanyin Deng; J'Nelle Young; A Wayne Vogl
A novel subcellular machine contributes to Basal junction remodeling in the seminiferous epithelium.

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2013: Kenji Momose; Kentaro Nobutani; Yohei Shimono; Takeshi Azuma; Akihiro Minami; Kiyohito Mizutani; Yoshimi Takai
miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling.
Genes to cells : devoted to molecular & cellular mechanisms 2013;18(3):195-202.
2013: Kenji Mandai; Yoshiyuki Rikitake; Yohei Shimono; Yoshimi Takai
Afadin/AF-6 and canoe: roles in cell adhesion and beyond.
Progress in molecular biology and translational science 2013;116():433-54.
2013: Min Du; B Brett Finlay; Peter K Nicholls; Calvin D Roskelley; Peter G Stanton; Yoshimi Takai; Jane Cipollone; Marc De Asis; Wanyin Deng; J'Nelle Young; A Wayne Vogl
A novel subcellular machine contributes to Basal junction remodeling in the seminiferous epithelium.
Biology of reproduction 2013;88(3):60.
2012: Seimi Satomi-Kobayashi; Yoshimi Takai; Yujiro Asada; Noriaki Emoto; Kinta Hatakeyama; Ken-Ichi Hirata; Tatsuro Ishida; Mitsuo Kinugasa; Reiko Kobayashi; Yusuke Kurogane; Yoshiyuki Rikitake
Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER).
The Journal of biological chemistry 2012;287(36):30336-45.
2012: Yoshiyuki Rikitake; Kenji Mandai; Yoshimi Takai
The role of nectins in different types of cell-cell adhesion.
Journal of cell science 2012;125(Pt 16):3713-22.
2012: Midori Yoshida; Hideru Togashi; Takahide Komori; Kiyomi Matsuzaki; Jun Miyoshi; Akira Mizoguchi; Yohei Shimono; Yoshimi Takai
Periderm cells covering palatal shelves have tight junctions and their desquamation reduces the polarity of palatal shelf epithelial cells in palatogenesis.
Genes to cells : devoted to molecular & cellular mechanisms 2012;17(6):455-72.
2012: Mitsuo Kinugasa; Yoshiki Kubo; Fumie Kureha; Yusuke Kurogane; Muneaki Miyata; Jun Miyoshi; Yuichi Nagamatsu; Kazuhiko Nakayama; Hisayuki Amano; Ken-Ichi Hirata; Seimi Satomi-Kobayashi; Yoshimi Takai; Shota Yamana; Yoshiyuki Rikitake
Necl-5/poliovirus receptor interacts with VEGFR2 and regulates VEGF-induced angiogenesis.
Circulation research 2012;110(5):716-26.
2012: J'Nelle S Young; Katarina L Kojic; Yoshimi Takai; A Wayne Vogl
Internalization of adhesion junction proteins and their association with recycling endosome marker proteins in rat seminiferous epithelium.
Reproduction (Cambridge, England) 2012;143(3):347-57.
2012: Yohei Shimono; Kenji Mandai; Masahiro Mori; Yoshiyuki Rikitake; Yoshimi Takai
Immunoglobulin superfamily receptors and adherens junctions.
Sub-cellular biochemistry 2012;60():137-70.
2011: Souichi Kurita; Hisakazu Ogita; Yoshimi Takai
Cooperative role of nectin-nectin and nectin-afadin interactions in formation of nectin-based cell-cell adhesion.
The Journal of biological chemistry 2011;286(42):36297-303.
2011: Kiyohito Mizutani; Wataru Ikeda; Satoshi Kawano; Akihiro Minami; Masazumi Waseda; Yoshimi Takai
Interaction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomes.
The Journal of biological chemistry 2011;286(42):36667-76.
2011: Hideru Togashi; Masazumi Waseda; Masatoshi Takeichi; Kanoko Kominami; Hitomi Komura; Jun Miyoshi; Yoshimi Takai
Nectins establish a checkerboard-like cellular pattern in the auditory epithelium.
Science (New York, N.Y.) 2011;333(6046):1144-7.
2011: Miki Tanaka-Okamoto; Shigenobu Yonemura; Sachiko Onishi; Yoshimi Takai; Keiko Hori; Hiroyoshi Ishizaki; Yu Itoh; Jun Miyoshi
Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia.
Journal of cell science 2011;124(Pt 13):2231-40.
2011: Hirotaka Narita; Yasunori Yamamoto; Mamoru Suzuki; Naoyuki Miyazaki; Asuka Yoshida; Katsuhisa Kawai; Kenji Iwasaki; Atsushi Nakagawa; Yoshimi Takai; Toshiaki Sakisaka
Crystal Structure of the cis-Dimer of Nectin-1: implications for the architecture of cell-cell junctions.
The Journal of biological chemistry 2011;286(14):12659-69.
2011: Yoshiyuki Rikitake; Yoshimi Takai
Directional cell migration regulation by small G proteins, nectin-like molecule-5, and afadin.
International review of cell and molecular biology 2011;287():97-143.
2010: Akihiro Minami; Kiyohito Mizutani; Masazumi Waseda; Mihoko Kajita; Muneaki Miyata; Wataru Ikeda; Yoshimi Takai
Necl-5/PVR enhances PDGF-induced attraction of growing microtubules to the plasma membrane of the leading edge of moving NIH3T3 cells.
Genes to cells : devoted to molecular & cellular mechanisms 2010;15(11):1123-35.
2010: Satoshi Kawano; Kiyohito Mizutani; Muneaki Miyata; Wataru Ikeda; Yoshimi Takai
Interaction of integrin alpha(6)beta(4) with ErbB3 and implication in heregulin-induced ErbB3/ErbB2-mediated DNA synthesis.
Genes to cells : devoted to molecular & cellular mechanisms 2010;15(9):995-1001.
2010: Hideto Tawa; Yoshiyuki Rikitake; Motonori Takahashi; Hisayuki Amano; Muneaki Miyata; Seimi Satomi-Kobayashi; Mitsuo Kinugasa; Yuichi Nagamatsu; Takashi Majima; Hisakazu Ogita; Jun Miyoshi; Ken-Ichi Hirata; Yoshimi Takai
Role of afadin in vascular endothelial growth factor- and sphingosine 1-phosphate-induced angiogenesis.
Circulation research 2010;106(11):1731-42.
2010: Reiko Nakai; Yoshimasa Maniwa; Yugo Tanaka; Wataru Nishio; Masahiro Yoshimura; Yutaka Okita; Chiho Ohbayashi; Naoyuki Satoh; Hisakazu Ogita; Yoshimi Takai; Yoshitake Hayashi
Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma.
Cancer science 2010;101(5):1326-30.
2010: Takako Ooshio; Reiko Kobayashi; Wataru Ikeda; Muneaki Miyata; Yuri Fukumoto; Naomi Matsuzawa; Hisakazu Ogita; Yoshimi Takai
Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells.
The Journal of biological chemistry 2010;285(7):5003-12.
2010: Taichi Murakami; Hideharu Abe; Kojiro Nagai; Tatsuya Tominaga; Norimichi Takamatsu; Toshikazu Araoka; Seiji Kishi; Toshikazu Takahashi; Akira Mima; Yoshimi Takai; Jeffrey B Kopp; Toshio Doi
Trophoblast glycoprotein: possible candidate mediating podocyte injuries in glomerulonephritis.
American journal of nephrology 2010;32(6):505-21.
2010: Hisakazu Ogita; Yoshiyuki Rikitake; Jun Miyoshi; Yoshimi Takai
Cell adhesion molecules nectins and associating proteins: Implications for physiology and pathology.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2010;86(6):621-9.
2009: Muneaki Miyata; Hisakazu Ogita; Hitomi Komura; Shinsuke Nakata; Ryoko Okamoto; Misa Ozaki; Takashi Majima; Naomi Matsuzawa; Satoshi Kawano; Akihiro Minami; Masumi Waseda; Naoyuki Fujita; Kiyohito Mizutani; Yoshiyuki Rikitake; Yoshimi Takai
Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor.
Journal of cell science 2009;122(Pt 23):4319-29.
2009: Muneaki Miyata; Yoshiyuki Rikitake; Motonori Takahashi; Yuichi Nagamatsu; Yusuke Yamauchi; Hisakazu Ogita; Ken-ichi Hirata; Yoshimi Takai
Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.
The Journal of biological chemistry 2009;284(36):24595-609.
2009: Satoshi Kawano; Wataru Ikeda; Megumi Kishimoto; Hisakazu Ogita; Yoshimi Takai
Silencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2.
The Journal of biological chemistry 2009;284(35):23793-805.
2009: Takashi Majima; Hisakazu Ogita; Tomohiro Yamada; Hisayuki Amano; Hideru Togashi; Toshiaki Sakisaka; Miki Tanaka-Okamoto; Hiroyoshi Ishizaki; Jun Miyoshi; Yoshimi Takai
Involvement of afadin in the formation and remodeling of synapses in the hippocampus.
Biochemical and biophysical research communications 2009;385(4):539-44.
2009: Hideru Togashi; Toshiaki Sakisaka; Yoshimi Takai
Cell adhesion molecules in the central nervous system.
Cell adhesion & migration 2009;3(1):29-35.
2008: Toshiaki Sakisaka; Yasunori Yamamoto; Sumiko Mochida; Michiko Nakamura; Kouki Nishikawa; Hiroyoshi Ishizaki; Miki Okamoto-Tanaka; Jun Miyoshi; Yoshinori Fujiyoshi; Toshiya Manabe; Yoshimi Takai
Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release.
The Journal of cell biology 2008;183(2):323-37.
2008: Hisakazu Ogita; Wataru Ikeda; Yoshimi Takai
Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.
Journal of microscopy 2008;231(3):455-65.
2008: Yoshimi Takai; Jun Miyoshi; Wataru Ikeda; Hisakazu Ogita
Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation.
Nature reviews. Molecular cell biology 2008;9(8):603-15.
2008: Kaori Kuramitsu; Wataru Ikeda; Naoya Inoue; Yoshiyuki Tamaru; Yoshimi Takai
Novel role of nectin: implication in the co-localization of JAM-A and claudin-1 at the same cell-cell adhesion membrane domain.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(8):797-805.
2008: Noriyuki Kanzaki; Hisakazu Ogita; Hitomi Komura; Misa Ozaki; Yasuhisa Sakamoto; Takashi Majima; Takeshi Ijuin; Tadaomi Takenawa; Yoshimi Takai
Involvement of the nectin-afadin complex in PDGF-induced cell survival.
Journal of cell science 2008;121(Pt 12):2008-17.
2008: Motonori Takahashi; Yoshiyuki Rikitake; Yuichi Nagamatsu; Tetsuya Hara; Wataru Ikeda; Ken-ichi Hirata; Yoshimi Takai
Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(6):549-69.
2008: Yuichi Nagamatsu; Yoshiyuki Rikitake; Motonori Takahashi; Yuko Deki; Wataru Ikeda; Ken-ichi Hirata; Yoshimi Takai
Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.
The Journal of biological chemistry 2008;283(21):14532-41.
2008: Hisayuki Amano; Wataru Ikeda; Satoshi Kawano; Mihoko Kajita; Yoshiyuki Tamaru; Naoya Inoue; Yukiko Minami; Akio Yamada; Yoshimi Takai
Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(3):269-84.
2008: Jun Miyoshi; Yoshimi Takai
Structural and functional associations of apical junctions with cytoskeleton.
Biochimica et biophysica acta 2008;1778(3):670-91.
2008: Yasuhisa Sakamoto; Hisakazu Ogita; Hitomi Komura; Yoshimi Takai
Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesion.
The Journal of biological chemistry 2008;283(1):496-505.
2008: Yoshimi Takai; Wataru Ikeda; Hisakazu Ogita; Yoshiyuki Rikitake
The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.
Annual review of cell and developmental biology 2008;24():309-42.
2008: Ayuko Sakane; Jun Miyoshi; Yoshimi Takai; Takuya Sasaki
Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome.
Methods in enzymology 2008;438():131-9.
2008: Toshiaki Sakisaka; Yoshimi Takai
A cell-free assay for endocytosis of E-cadherin.
Methods in molecular biology (Clifton, N.J.) 2008;440():77-87.
2008: Hisakazu Ogita; Yoshimi Takai
Cross-talk among integrin, cadherin, and growth factor receptor: roles of nectin and nectin-like molecule.
International review of cytology 2008;265():1-54.
2008: Hitomi Komura; Hisakazu Ogita; Wataru Ikeda; Akira Mizoguchi; Jun Miyoshi; Yoshimi Takai
Establishment of cell polarity by afadin during the formation of embryoid bodies.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(1):79-90.
2007: Shinsuke Nakata; Naoyuki Fujita; Yuichi Kitagawa; Ryoko Okamoto; Hisakazu Ogita; Yoshimi Takai
Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2: implications for cellular morphology.
The Journal of biological chemistry 2007;282(52):37815-25.
2007: Toshiaki Sakisaka; Wataru Ikeda; Hisakazu Ogita; Naoyuki Fujita; Yoshimi Takai
The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors.
Current opinion in cell biology 2007;19(5):593-602.
2007: Shu Hisata; Toshiaki Sakisaka; Takeshi Baba; Tomohiro Yamada; Kazuhiro Aoki; Michiyuki Matsuda; Yoshimi Takai
Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth.
The Journal of cell biology 2007;178(5):843-60.
2007: Takako Ooshio; Naoyuki Fujita; Akio Yamada; Tatsuhiro Sato; Yuichi Kitagawa; Ryoko Okamoto; Shinsuke Nakata; Ayaka Miki; Kenji Irie; Yoshimi Takai
Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions.
Journal of cell science 2007;120(Pt 14):2352-65.
2007: Kotaro Wakamatsu; Hisakazu Ogita; Noriko Okabe; Kenji Irie; Miki Tanaka-Okamoto; Hiroyoshi Ishizaki; Akemi Ishida-Yamamoto; Hajime Iizuka; Jun Miyoshi; Yoshimi Takai
Up-regulation of loricrin expression by cell adhesion molecule nectin-1 through Rap1-ERK signaling in keratinocytes.
The Journal of biological chemistry 2007;282(25):18173-81.
2007: Yukiko Minami; Wataru Ikeda; Mihoko Kajita; Tsutomu Fujito; Hisayuki Amano; Yoshiyuki Tamaru; Kaori Kuramitsu; Yasuhisa Sakamoto; Morito Monden; Yoshimi Takai
Necl-5/poliovirus receptor interacts in cis with integrin alphaVbeta3 and regulates its clustering and focal complex formation.
The Journal of biological chemistry 2007;282(25):18481-96.
2007: Misa Ozaki; Hisakazu Ogita; Yoshimi Takai
Involvement of integrin-induced activation of protein kinase C in the formation of adherens junctions.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(5):651-62.
2007: Yoshikazu Tsukasaki; Kazuo Kitamura; Kazuya Shimizu; Atsuko Hikikoshi Iwane; Yoshimi Takai; Toshio Yanagida
Role of multiple bonds between the single cell adhesion molecules, nectin and cadherin, revealed by high sensitive force measurements.
Journal of molecular biology 2007;367(4):996-1006.
2007: Mihoko Kajita; Wataru Ikeda; Yoshiyuki Tamaru; Yoshimi Takai
Regulation of platelet-derived growth factor-induced Ras signaling by poliovirus receptor Necl-5 and negative growth regulator Sprouty2.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(3):345-57.
2007: Yukiko Minami; Wataru Ikeda; Mihoko Kajita; Tsutomu Fujito; Morito Monden; Yoshimi Takai
Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells.
Biochemical and biophysical research communications 2007;352(4):856-60.
2007: Jun Miyoshi; Yoshimi Takai
Nectin and nectin-like molecules: biology and pathology.
American journal of nephrology 2007;27(6):590-604.
2006: Hiroyoshi Ishizaki; Atsushi Togawa; Miki Tanaka-Okamoto; Keiko Hori; Miyuki Nishimura; Akiko Hamaguchi; Toshio Imai; Yoshimi Takai; Jun Miyoshi
Defective chemokine-directed lymphocyte migration and development in the absence of Rho guanosine diphosphate-dissociation inhibitors alpha and beta.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(12):8512-21.
2006: Maiko Inagaki; Kenji Irie; Hiroyoshi Ishizaki; Miki Tanaka-Okamoto; Jun Miyoshi; Yoshimi Takai
Role of cell adhesion molecule nectin-3 in spermatid development.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(9):1125-32.
2006: Akio Yamada; Naoyuki Fujita; Tatsuhiro Sato; Ryoko Okamoto; Takako Ooshio; Takeshi Hirota; Koji Morimoto; Kenji Irie; Yoshimi Takai
Requirement of nectin, but not cadherin, for formation of claudin-based tight junctions in annexin II-knockdown MDCK cells.
Oncogene 2006;25(37):5085-102.
2006: Yasuhisa Sakamoto; Hisakazu Ogita; Takeshi Hirota; Tomomi Kawakatsu; Taihei Fukuyama; Masato Yasumi; Noriyuki Kanzaki; Misa Ozaki; Yoshimi Takai
Interaction of integrin alpha(v)beta3 with nectin. Implication in cross-talk between cell-matrix and cell-cell junctions.
The Journal of biological chemistry 2006;281(28):19631-44.
2006: Yoshimi Takai
[Role of nectins and nectin-like molecules in cell adhesion--a lesson on cell biology from the late Dr. Shoichiro Tsukita].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(7):631-46.
2006: Ayuko Sakane; Shinji Manabe; Hiroyoshi Ishizaki; Miki Tanaka-Okamoto; Emi Kiyokage; Kazunori Toida; Takayuki Yoshida; Jun Miyoshi; Haruyuki Kamiya; Yoshimi Takai; Takuya Sasaki
Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):10029-34.
2006: Eiji Inoue; Maki Deguchi-Tawarada; Etsuko Takao-Rikitsu; Marie Inoue; Isao Kitajima; Toshihisa Ohtsuka; Yoshimi Takai
ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(6):659-72.
2006: Hisakazu Ogita; Yoshimi Takai
Nectins and nectin-like molecules: roles in cell adhesion, polarization, movement, and proliferation.
IUBMB life 2006;58(5-6):334-43.
2006: Eiji Inoue; Sumiko Mochida; Hiroshi Takagi; Susumu Higa; Maki Deguchi-Tawarada; Etsuko Takao-Rikitsu; Marie Inoue; Ikuko Yao; Kosei Takeuchi; Isao Kitajima; Mitsutoshi Setou; Toshihisa Ohtsuka; Yoshimi Takai
SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.
Neuron 2006;50(2):261-75.
2006: Toshihiro Kimura; Toshiaki Sakisaka; Takeshi Baba; Tomohiro Yamada; Yoshimi Takai
Involvement of the Ras-Ras-activated Rab5 guanine nucleotide exchange factor RIN2-Rab5 pathway in the hepatocyte growth factor-induced endocytosis of E-cadherin.
The Journal of biological chemistry 2006;281(15):10598-609.
2006: Maki Deguchi-Tawarada; Eiji Inoue; Etsuko Takao-Rikitsu; Marie Inoue; Isao Kitajima; Toshihisa Ohtsuka; Yoshimi Takai
Active zone protein CAST is a component of conventional and ribbon synapses in mouse retina.
The Journal of comparative neurology 2006;495(4):480-96.
2006: Tatsuhiro Sato; Naoyuki Fujita; Akio Yamada; Takako Ooshio; Ryoko Okamoto; Kenji Irie; Yoshimi Takai
Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells.
The Journal of biological chemistry 2006;281(8):5288-99.
2006: Tomoyuki Honda; Toshiaki Sakisaka; Tomohiro Yamada; Noriko Kumazawa; Takashi Hoshino; Mihoko Kajita; Tetsuro Kayahara; Hiroyoshi Ishizaki; Miki Tanaka-Okamoto; Akira Mizoguchi; Toshiya Manabe; Jun Miyoshi; Yoshimi Takai
Involvement of nectins in the formation of puncta adherentia junctions and the mossy fiber trajectory in the mouse hippocampus.
Molecular and cellular neurosciences 2006;31(2):315-25.
2006: Taihei Fukuyama; Hisakazu Ogita; Tomomi Kawakatsu; M Inagaki; Yoshimi Takai
Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway.
Oncogene 2006;25(1):8-19.
2006: Hisakazu Ogita; Yoshimi Takai
Activation of Rap1, Cdc42, and rac by nectin adhesion system.
Methods in enzymology 2006;406():415-24.
2005: Toshiaki Sakisaka; Yoshimi Takai
Cell adhesion molecules in the CNS.
Journal of cell science 2005;118(Pt 23):5407-10.
2005: Tsutomu Fujito; Wataru Ikeda; Shigeki Kakunaga; Yukiko Minami; Mihoko Kajita; Yasuhisa Sakamoto; Morito Monden; Yoshimi Takai
Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3.
The Journal of cell biology 2005;171(1):165-73.
2005: Takeshi Baba; Toshiaki Sakisaka; Sumiko Mochida; Yoshimi Takai
PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter.
The Journal of cell biology 2005;170(7):1113-25.
2005: Tomohiro Yamada; Toshiaki Sakisaka; Shu Hisata; Takeshi Baba; Yoshimi Takai
RA-RhoGAP, Rap-activated Rho GTPase-activating protein implicated in neurite outgrowth through Rho.
The Journal of biological chemistry 2005;280(38):33026-34.
2005: Tatsuhiro Sato; Kenji Irie; Ryoko Okamoto; Takako Ooshio; Naoyuki Fujita; Yoshimi Takai
Common signaling pathway is used by the trans-interaction of Necl-5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell-cell adhesion.
Cancer science 2005;96(9):578-89.
2005: Rikako Kawagishi; Masahiro Tahara; Ken-ichirou Morishige; Masahiro Sakata; Keiichi Tasaka; Wataru Ikeda; Koji Morimoto; Yoshimi Takai; Yuji Murata
Expression of nectin-2 in mouse granulosa cells.
European journal of obstetrics, gynecology, and reproductive biology 2005;121(1):71-6.
2005: Takashi Hoshino; Toshiaki Sakisaka; Takeshi Baba; Tomohiro Yamada; Toshihiro Kimura; Yoshimi Takai
Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn.
The Journal of biological chemistry 2005;280(25):24095-103.
2005: Ryoko Okamoto; Kenji Irie; Akio Yamada; Tatsuo Katata; Atsunori Fukuhara; Yoshimi Takai
Recruitment of E-cadherin associated with alpha- and beta-catenins and p120ctn to the nectin-based cell-cell adhesion sites by the action of 12-O-tetradecanoylphorbol-13-acetate in MDCK cells.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(5):435-45.
2005: Jun Miyoshi; Yoshimi Takai
Molecular perspective on tight-junction assembly and epithelial polarity.
Advanced drug delivery reviews 2005;57(6):815-55.
2005: Maiko Inagaki; Kenji Irie; Hiroyoshi Ishizaki; Miki Tanaka-Okamoto; Koji Morimoto; Eiji Inoue; Toshihisa Ohtsuka; Jun Miyoshi; Yoshimi Takai
Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development.
Development (Cambridge, England) 2005;132(7):1525-37.
2005: Takeshi Hirota; Kenji Irie; Ryoko Okamoto; Wataru Ikeda; Yoshimi Takai
Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf-MEK-ERK-AP-1 pathway.
Oncogene 2005;24(13):2229-35.
2005: Shigeki Kakunaga; Wataru Ikeda; Shinsuke Itoh; Maki Deguchi-Tawarada; Toshihisa Ohtsuka; Akira Mizoguchi; Yoshimi Takai
Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.
Journal of cell science 2005;118(Pt 6):1267-77.
2005: Masato Yasumi; Toshiaki Sakisaka; Takashi Hoshino; Toshihiro Kimura; Yasuhisa Sakamoto; Tomoyuki Yamanaka; Shigeo Ohno; Yoshimi Takai
Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.
The Journal of biological chemistry 2005;280(8):6761-5.
2005: Akio Yamada; Kenji Irie; Takeshi Hirota; Takako Ooshio; Atsunori Fukuhara; Yoshimi Takai
Involvement of the annexin II-S100A10 complex in the formation of E-cadherin-based adherens junctions in Madin-Darby canine kidney cells.
The Journal of biological chemistry 2005;280(7):6016-27.
2005: Tomomi Kawakatsu; Hisakazu Ogita; Tatsuro Fukuhara; Taihei Fukuyama; Yukiko Minami; Kazuya Shimizu; Yoshimi Takai
Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac.
The Journal of biological chemistry 2005;280(6):4940-7.
2005: Taihei Fukuyama; Hisakazu Ogita; Tomomi Kawakatsu; Tatsuro Fukuhara; Tomohiro Yamada; Tatsuhiro Sato; Kazuya Shimizu; Takeshi Nakamura; Michiyuki Matsuda; Yoshimi Takai
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.
The Journal of biological chemistry 2005;280(1):815-25.
2004: Kenji Irie; Kazuya Shimizu; Toshiaki Sakisaka; Wataru Ikeda; Yoshimi Takai
Roles and modes of action of nectins in cell-cell adhesion.
Seminars in cell & developmental biology 2004;15(6):643-56.
2004: Jun Miyoshi; Yoshimi Takai
Dual role of DENN/MADD (Rab3GEP) in neurotransmission and neuroprotection.
Trends in molecular medicine 2004;10(10):476-80.
2004: Toshiaki Sakisaka; Yoshimi Takai
Biology and pathology of nectins and nectin-like molecules.
Current opinion in cell biology 2004;16(5):513-21.
2004: Noriko Okabe; Kazuya Shimizu; Kumi Ozaki-Kuroda; Hiroyuki Nakanishi; Koji Morimoto; Masakazu Takeuchi; Hironobu Katsumaru; Fujio Murakami; Yoshimi Takai
Contacts between the commissural axons and the floor plate cells are mediated by nectins.
Developmental biology 2004;273(2):244-56.
2004: Akio Yamada; Kenji Irie; Atsunori Fukuhara; Takako Ooshio; Yoshimi Takai
Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(9):843-55.
2004: Tatsuhiro Sato; Kenji Irie; Takako Ooshio; Wataru Ikeda; Yoshimi Takai
Involvement of heterophilic trans-interaction of Necl-5/Tage4/PVR/CD155 with nectin-3 in formation of nectin- and cadherin-based adherens junctions.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(9):791-9.
2004: Shigeki Kakunaga; Wataru Ikeda; Tatsushi Shingai; Tsutomu Fujito; Akio Yamada; Yukiko Minami; Toshio Imai; Yoshimi Takai
Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling.
The Journal of biological chemistry 2004;279(35):36419-25.
2004: Masanori Asada; Kenji Irie; Akio Yamada; Yoshimi Takai
Afadin- and alpha-actinin-binding protein ADIP directly binds beta'-COP, a subunit of the coatomer complex.
Biochemical and biophysical research communications 2004;321(2):350-4.
2004: Tatsuro Fukuhara; Kazuya Shimizu; Tomomi Kawakatsu; Taihei Fukuyama; Yukiko Minami; Tomoyuki Honda; Takashi Hoshino; Tomohiro Yamada; Hisakazu Ogita; Masato Okada; Yoshimi Takai
Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.
The Journal of cell biology 2004;166(3):393-405.
2004: Takako Ooshio; Kenji Irie; Koji Morimoto; Atsunori Fukuhara; Toshio Imai; Yoshimi Takai
Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells.
The Journal of biological chemistry 2004;279(30):31365-73.
2004: Genkichi Izumi; Toshiaki Sakisaka; Takeshi Baba; Shintaro Tanaka; Koji Morimoto; Yoshimi Takai
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments.
The Journal of cell biology 2004;166(2):237-48.
2004: Toshiaki Sakisaka; Takeshi Baba; Shintaro Tanaka; Genkichi Izumi; Masato Yasumi; Yoshimi Takai
Regulation of SNAREs by tomosyn and ROCK: implication in extension and retraction of neurites.
The Journal of cell biology 2004;166(1):17-25.
2004: Yasunori Yamamoto; Kenji Irie; Masanori Asada; Akihisa Mino; Kenji Mandai; Yoshimi Takai
Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.
Oncogene 2004;23(22):3889-97.
2004: Noriko Okabe; Kumi Ozaki-Kuroda; Hiroyuki Nakanishi; Kazuya Shimizu; Yoshimi Takai
Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;230(1):174-86.
2004: Wataru Ikeda; Shigeki Kakunaga; Kyoji Takekuni; Tatsushi Shingai; Keiko Satoh; Koji Morimoto; Masakazu Takeuchi; Toshio Imai; Yoshimi Takai
Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.
The Journal of biological chemistry 2004;279(17):18015-25.
2004: Yasunori Yamamoto; Kenji Irie; Hidetake Kurihara; Tatsuo Sakai; Yoshimi Takai
Vmac: a novel protein associated with vimentin-type intermediate filament in podocytes of rat kidney.
Biochemical and biophysical research communications 2004;315(4):1120-5.
2004: Takashi Hoshino; Kazuya Shimizu; Tomoyuki Honda; Tomomi Kawakatsu; Taihei Fukuyama; Takeshi Nakamura; Michiyuki Matsuda; Yoshimi Takai
A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.
Molecular biology of the cell 2004;15(3):1077-88.
2004: Etsuko Takao-Rikitsu; Sumiko Mochida; Eiji Inoue; Maki Deguchi-Tawarada; Marie Inoue; Toshihisa Ohtsuka; Yoshimi Takai
Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.
The Journal of cell biology 2004;164(2):301-11.
2004: Kenji Irie; Kazuya Shimizu; Toshiaki Sakisaka; Wataru Ikeda; Yoshimi Takai
Roles of nectins in cell adhesion, signaling and polarization.
Handbook of experimental pharmacology 2004;(165):343-72.
2004: Maki Deguchi-Tawarada; Eiji Inoue; Etsuko Takao-Rikitsu; Marie Inoue; Toshihisa Ohtsuka; Yoshimi Takai
CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(1):15-23.
2003: Atsunori Fukuhara; Kazuya Shimizu; Tomomi Kawakatsu; Tatsuro Fukuhara; Yoshimi Takai
Involvement of nectin-activated Cdc42 small G protein in organization of adherens and tight junctions in Madin-Darby canine kidney cells.
The Journal of biological chemistry 2003;278(51):51885-93.
2003: Hirokazu Nakahara; Tomohiro Otani; Takuya Sasaki; Yasuhiro Miura; Yoshimi Takai; Mikihiko Kogo
Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(12):1019-27.
2003: Akio Yamada; Kenji Irie; Maki Deguchi-Tawarada; Toshihisa Ohtsuka; Yoshimi Takai
Nectin-dependent localization of synaptic scaffolding molecule (S-SCAM) at the puncta adherentia junctions formed between the mossy fibre terminals and the dendrites of pyramidal cells in the CA3 area of the mouse hippocampus.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(12):985-94.
2003: Kazuya Shimizu; Yoshimi Takai
Roles of the intercellular adhesion molecule nectin in intracellular signaling.
Journal of biochemistry 2003;134(5):631-6.
2003: Yoshimi Takai; Kazuya Shimizu; Toshihisa Ohtsuka
The roles of cadherins and nectins in interneuronal synapse formation.
Current opinion in neurobiology 2003;13(5):520-6.
2003: Tatsushi Shingai; Wataru Ikeda; Shigeki Kakunaga; Koji Morimoto; Kyoji Takekuni; Shinsuke Itoh; Keiko Satoh; Masakazu Takeuchi; Toshio Imai; Morito Monden; Yoshimi Takai
Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells.
The Journal of biological chemistry 2003;278(37):35421-7.
2003: Yoshimi Takai; Kenji Irie; Kazuya Shimizu; Toshiaki Sakisaka; Wataru Ikeda
Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.
Cancer science 2003;94(8):655-67.
2003: Wataru Ikeda; Shigeki Kakunaga; Shinsuke Itoh; Tatsushi Shingai; Kyoji Takekuni; Keiko Satoh; Yoko Inoue; Akiko Hamaguchi; Koji Morimoto; Masakazu Takeuchi; Toshio Imai; Yoshimi Takai
Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration.
The Journal of biological chemistry 2003;278(30):28167-72.
2003: Tomoyuki Honda; Kazuya Shimizu; Atsunori Fukuhara; Kenji Irie; Yoshimi Takai
Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions.
Biochemical and biophysical research communications 2003;306(1):104-9.
2003: Maiko Inagaki; Kenji Irie; Maki Deguchi-Tawarada; Wataru Ikeda; Toshihisa Ohtsuka; Masakazu Takeuchi; Yoshimi Takai
Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus.
The Journal of comparative neurology 2003;460(4):514-24.
2003: Hiroshi Kawabe; Toshiaki Sakisaka; Masato Yasumi; Tatsushi Shingai; Genkichi Izumi; Fumiko Nagano; Maki Deguchi-Tawarada; Masakazu Takeuchi; Hiroyuki Nakanishi; Yoshimi Takai
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(6):537-46.
2003: Tomoyuki Honda; Kazuya Shimizu; Tomomi Kawakatsu; Atsunori Fukuhara; Kenji Irie; Takeshi Nakamura; Michiyuki Matsuda; Yoshimi Takai
Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(5):481-91.
2003: Tatsuo Katata; Kenji Irie; Atsunori Fukuhara; Tomomi Kawakatsu; Akio Yamada; Kazuya Shimizu; Yoshimi Takai
Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells.
Oncogene 2003;22(14):2097-109.
2003: Yoshinari Tanaka; Hiroyuki Nakanishi; Shigeki Kakunaga; Noriko Okabe; Tomomi Kawakatsu; Kazuya Shimizu; Yoshimi Takai
Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.
Molecular biology of the cell 2003;14(4):1597-609.
2003: Masato Yasumi; Kazuya Shimizu; Tomoyuki Honda; Masakazu Takeuchi; Yoshimi Takai
Role of each immunoglobulin-like loop of nectin for its cell-cell adhesion activity.
Biochemical and biophysical research communications 2003;302(1):61-6.
2003: Kyoji Takekuni; Wataru Ikeda; Tsutomu Fujito; Koji Morimoto; Masakazu Takeuchi; Morito Monden; Yoshimi Takai
Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.
The Journal of biological chemistry 2003;278(8):5497-500.
2003: Masanori Asada; Kenji Irie; Koji Morimoto; Akio Yamada; Wataru Ikeda; Masakazu Takeuchi; Yoshimi Takai
ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.
The Journal of biological chemistry 2003;278(6):4103-11.
2003: Tatsuo Katata; Kenji Irie; Yoshimi Takai
[Role of the nectin-afadin system in organization of tight and adherens junctions in epithelial cells].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(2):105-12.
2003: Tomoyuki Honda; Kazuya Shimizu; Tomomi Kawakatsu; Masato Yasumi; Tatsushi Shingai; Atsunori Fukuhara; Kumi Ozaki-Kuroda; Kenji Irie; Hiroyuki Nakanishi; Yoshimi Takai
Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(1):51-63.
2003: Yoshimi Takai; Hiroyuki Nakanishi
Nectin and afadin: novel organizers of intercellular junctions.
Journal of cell science 2003;116(Pt 1):17-27.
2002: Tomomi Kawakatsu; Kazuya Shimizu; Tomoyuki Honda; Tatsuro Fukuhara; Takashi Hoshino; Yoshimi Takai
Trans-interactions of nectins induce formation of filopodia and Lamellipodia through the respective activation of Cdc42 and Rac small G proteins.
The Journal of biological chemistry 2002;277(52):50749-55.
2002: Yoshinari Tanaka; Kenji Irie; Takeshi Hirota; Toshiaki Sakisaka; Hiroyuki Nakanishi; Yoshimi Takai
Ectodomain shedding of nectin-1alpha by SF/HGF and TPA in MDCK cells.
Biochemical and biophysical research communications 2002;299(3):472-8.
2002: Atsunori Fukuhara; Kenji Irie; Hiroyuki Nakanishi; Kyoji Takekuni; Tomomi Kawakatsu; Wataru Ikeda; Akio Yamada; Tatsuo Katata; Tomoyuki Honda; Tatsuhiro Sato; Kazuya Shimizu; Harunobu Ozaki; Hisanori Horiuchi; Toru Kita; Yoshimi Takai
Involvement of nectin in the localization of junctional adhesion molecule at tight junctions.
Oncogene 2002;21(50):7642-55.
2002: Atsunori Fukuhara; Kenji Irie; Akio Yamada; Tatsuo Katata; Tomoyuki Honda; Kazuya Shimizu; Hiroyuki Nakanishi; Yoshimi Takai
Role of nectin in organization of tight junctions in epithelial cells.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(10):1059-72.
2002: Toshihisa Ohtsuka; Etsuko Takao-Rikitsu; Eiji Inoue; Marie Inoue; Masakazu Takeuchi; Kaho Matsubara; Maki Deguchi-Tawarada; Keiko Satoh; Koji Morimoto; Hiroyuki Nakanishi; Yoshimi Takai
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.
The Journal of cell biology 2002;158(3):577-90.
2002: Kumi Ozaki-Kuroda; Hiroyuki Nakanishi; Hiroshi Ohta; Hiromitsu Tanaka; Hidetake Kurihara; Steffen Mueller; Kenji Irie; Wataru Ikeda; Tatsuo Sakai; Eckard Wimmer; Yoshitake Nishimune; Yoshimi Takai
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.
Current biology : CB 2002;12(13):1145-50.
2002: Ying-Feng Peng; Kenji Mandai; Hiroyuki Nakanishi; Wataru Ikeda; Masanori Asada; Yumiko Momose; Sayumi Shibamoto; Kazuyoshi Yanagihara; Hitoshi Shiozaki; Morito Monden; Masatoshi Takeichi; Yoshimi Takai
Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.
Oncogene 2002;21(26):4108-19.
2002: Yumiko Momose; Tomoyuki Honda; Maiko Inagaki; Kazuya Shimizu; Kenji Irie; Hiroyuki Nakanishi; Yoshimi Takai
Role of the second immunoglobulin-like loop of nectin in cell-cell adhesion.
Biochemical and biophysical research communications 2002;293(1):45-9.
2002: Yasunori Yamamoto; Kenji Mandai; Noriko Okabe; Takashi Hoshino; Hiroyuki Nakanishi; Yoshimi Takai
Localization of mLin-7 at nectin-based cell-cell junctions.
Oncogene 2002;21(16):2545-54.
2002: Yongman Kim; Wataru Ikeda; Hiroyuki Nakanishi; Yoshinari Tanaka; Kyoji Takekuni; Shinsuke Itoh; Morito Monden; Yoshimi Takai
Association of frabin with specific actin and membrane structures.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(4):413-20.
2002: Fumiko Nagano; Hiroshi Kawabe; Hiroyuki Nakanishi; Masahiko Shinohara; Maki Deguchi-Tawarada; Masakazu Takeuchi; Takuya Sasaki; Yoshimi Takai
Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family.
The Journal of biological chemistry 2002;277(12):9629-32.
2002: Akira Mizoguchi; Hiroyuki Nakanishi; Kazushi Kimura; Kaho Matsubara; Kumi Ozaki-Kuroda; Tatsuo Katata; Tomoyuki Honda; Yoshimoto Kiyohara; Kyun Heo; Mikito Higashi; Tomonari Tsutsumi; Satomi Sonoda; Chizuka Ide; Yoshimi Takai
Nectin: an adhesion molecule involved in formation of synapses.
The Journal of cell biology 2002;156(3):555-65.
2002: Keiko Satoh; Masakazu Takeuchi; Yoshiya Oda; Maki Deguchi-Tawarada; Yoshimasa Sakamoto; Kaho Matsubara; Takeshi Nagasu; Yoshimi Takai
Identification of activity-regulated proteins in the postsynaptic density fraction.
Genes to cells : devoted to molecular & cellular mechanisms 2002;7(2):187-97.
2002: Hiroyuki Nakanishi; Takuya Sasaki; Yoshimi Takai
Isolation of regulatory proteins for the Rab3 subfamily GTPases.
Methods in molecular biology (Clifton, N.J.) 2002;189():143-56.
2001: Hiroshi Kawabe; Hiroyuki Nakanishi; Masanori Asada; Atsunori Fukuhara; Koji Morimoto; Masakazu Takeuchi; Yoshimi Takai
Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells.
The Journal of biological chemistry 2001;276(51):48350-5.
2001: A Kodama; Takashi Matozaki; Masahiko Shinohara; Atsunori Fukuhara; K Tachibana; M Ichihashi; Hiroyuki Nakanishi; Yoshimi Takai
Regulation of Ras and Rho small G proteins by SHP-2.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(10):869-76.
2001: Wataru Ikeda; Hiroyuki Nakanishi; Kyoji Takekuni; Shinsuke Itoh; Yoshimi Takai
Identification of splicing variants of Frabin with partly different functions and tissue distribution.
Biochemical and biophysical research communications 2001;286(5):1066-72.
2001: Wataru Ikeda; Hiroyuki Nakanishi; Yuetsu Tanaka; K Tachibana; Yoshimi Takai
Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation.
Oncogene 2001;20(27):3457-63.
2001: Shigeyuki Yokoyama; K Tachibana; Hiroyuki Nakanishi; Yasunori Yamamoto; Kenji Irie; Kenji Mandai; A Nagafuchi; Morito Monden; Yoshimi Takai
alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadin.
Molecular biology of the cell 2001;12(6):1595-609.
2001: Masahiko Shinohara; A Kodama; Takashi Matozaki; Atsunori Fukuhara; K Tachibana; Hiroyuki Nakanishi; Yoshimi Takai
Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1.
The Journal of biological chemistry 2001;276(22):18941-6.
2001: Toshiaki Sakisaka; T Taniguchi; Hiroyuki Nakanishi; Kiyohisa Takahashi; M Miyahara; Wataru Ikeda; Shigeyuki Yokoyama; Ying-Feng Peng; Koichi Yamanishi; Yoshimi Takai
Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.
Journal of virology 2001;75(10):4734-43.
2001: Kumi Ozaki-Kuroda; Y Yamamoto; H Nohara; M Kinoshita; Tatsuji Fujiwara; Kenji Irie; Yoshimi Takai
Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae.
Molecular and cellular biology 2001;21(3):827-39.
2001: Fumiko Nagano; Takuya Sasaki; Yoshimi Takai
Purification and properties of Rab3 GTPase-activating protein.
Methods in enzymology 2001;329():67-75.
2001: Hiroyuki Nakanishi; Yoshimi Takai
Purification and properties of Rab3 GDP/GTP exchange protein.
Methods in enzymology 2001;329():59-67.
2001: Yoshimi Takai; Takuya Sasaki; Takashi Matozaki
Small GTP-binding proteins.
Physiological reviews 2001;81(1):153-208.
2000: Akihisa Mino; Toshihisa Ohtsuka; E Inoue; Yoshimi Takai
Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(12):1009-16.
2000: Ying-Feng Peng; Kenji Mandai; Toshiaki Sakisaka; Noriko Okabe; Y Yamamoto; Shigeyuki Yokoyama; Akira Mizoguchi; Hitoshi Shiozaki; Morito Monden; Yoshimi Takai
Ankycorbin: a novel actin cytoskeleton-associated protein.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(12):1001-8.
2000: Kenichi Hirano; Fumihiko Matsuura; Kosuke Tsukamoto; Zhongyan Zhang; Akifumi Matsuyama; K Takaishi; Ryutaro Komuro; T Suehiro; Shizuya Yamashita; Yoshimi Takai; Yuji Matsuzawa
Decreased expression of a member of the Rho GTPase family, Cdc42Hs, in cells from Tangier disease - the small G protein may play a role in cholesterol efflux.
FEBS letters 2000;484(3):275-9.
2000: K Takaishi; Takashi Matozaki; K Nakano; Yoshimi Takai
Multiple downstream signalling pathways from ROCK, a target molecule of Rho small G protein, in reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(11):929-936.
2000: H Ishizaki; J Miyoshi; H Kamiya; A Togawa; M Tanaka; T Sasaki; K Endo; Akira Mizoguchi; S Ozawa; Yoshimi Takai
Role of rab GDP dissociation inhibitor alpha in regulating plasticity of hippocampal neurotransmission.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11587-92.
2000: M Deguchi; T Iizuka; Yutaka Hata; Wataru Nishimura; K Hirao; Ikuko Yao; H Kawabe; Yoshimi Takai
PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.
The Journal of biological chemistry 2000;275(38):29875-80.
2000: K Tachibana; Hiroyuki Nakanishi; Kenji Mandai; K Ozaki; Wataru Ikeda; Yasunori Yamamoto; A Nagafuchi; Shoichiro Tsukita; Yoshimi Takai
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins.
The Journal of cell biology 2000;150(5):1161-76.
2000: H Nishioka; Akira Mizoguchi; Hiroyuki Nakanishi; Kenji Mandai; Kiyohisa Takahashi; K Kimura; A Satoh-Moriya; Yoshimi Takai
Localization of l-afadin at puncta adhaerentia-like junctions between the mossy fiber terminals and the dendritic trunks of pyramidal cells in the adult mouse hippocampus.
The Journal of comparative neurology 2000;424(2):297-306.
2000: M Kikyo; Takashi Matozaki; A Kodama; Hiroshi Kawabe; Hiroyuki Nakanishi; Yoshimi Takai
Cell-cell adhesion-mediated tyrosine phosphorylation of nectin-2delta, an immunoglobulin-like cell adhesion molecule at adherens junctions.
Oncogene 2000;19(35):4022-8.
2000: Takashi Matozaki; H Nakanishi; Yoshimi Takai
Small G-protein networks: their crosstalk and signal cascades.
Cellular signalling 2000;12(8):515-24.
2000: A Kodama; Takashi Matozaki; Atsunori Fukuhara; M Kikyo; M Ichihashi; Yoshimi Takai
Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.
Molecular biology of the cell 2000;11(8):2565-75.
2000: K Takaishi; Akihisa Mino; Wataru Ikeda; K Nakano; Yoshimi Takai
Mechanisms of activation and action of mDial in the formation of parallel stress fibers in MDCK cells.
Biochemical and biophysical research communications 2000;274(1):68-72.
2000: T Yasuda; T Ohtsuka; E Inoue; Shigeyuki Yokoyama; Toshiaki Sakisaka; A Kodama; K Takaishi; Yoshimi Takai
Importance of spatial activation of Cdc42 and rac small G proteins by frabin for microspike formation in MDCK cells.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(7):583-91.
2000: Y Ono; Hiroyuki Nakanishi; M Nishimura; M Kakizaki; Kiyohisa Takahashi; M Miyahara; K Satoh-Horikawa; Kenji Mandai; Yoshimi Takai
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.
Oncogene 2000;19(27):3050-8.
2000: Tatsuji Fujiwara; A Mammoto; Y Kim; Yoshimi Takai
Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2.
Biochemical and biophysical research communications 2000;271(3):626-9.
2000: A Mammoto; Takuya Sasaki; Y Kim; Yoshimi Takai
Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking.
The Journal of biological chemistry 2000;275(18):13167-70.
2000: A Takakura; J Miyoshi; H Ishizaki; M Tanaka; A Togawa; Y Nishizawa; H Yoshida; S i Nishikawa; Yoshimi Takai
Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling.
Molecular biology of the cell 2000;11(5):1875-86.
2000: Ikuko Yao; T Ohtsuka; H Kawabe; Y Matsuura; Yoshimi Takai; Yutaka Hata
Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1.
Biochemical and biophysical research communications 2000;270(2):538-42.
2000: K Satoh-Horikawa; Hiroyuki Nakanishi; Kiyohisa Takahashi; M Miyahara; M Nishimura; K Tachibana; Akira Mizoguchi; Yoshimi Takai
Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities.
The Journal of biological chemistry 2000;275(14):10291-9.
2000: K Hirao; Yutaka Hata; M Deguchi; Ikuko Yao; M Ogura; C Rokukawa; H Kawabe; Akira Mizoguchi; Yoshimi Takai
Association of synapse-associated protein 90/ postsynaptic density-95-associated protein (SAPAP) with neurofilaments.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(3):203-10.
2000: K Hirao; Yutaka Hata; Ikuko Yao; M Deguchi; H Kawabe; Akira Mizoguchi; Yoshimi Takai
Three isoforms of synaptic scaffolding molecule and their characterization. Multimerization between the isoforms and their interaction with N-methyl-D-aspartate receptors and SAP90/PSD-95-associated protein.
The Journal of biological chemistry 2000;275(4):2966-72.
2000: M Miyahara; Hiroyuki Nakanishi; Kiyohisa Takahashi; K Satoh-Horikawa; K Tachibana; Yoshimi Takai
Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction.
The Journal of biological chemistry 2000;275(1):613-8.
2000: Hiroshi Hibino; Atsushi Inanobe; Masayuki Tanemoto; Akikazu Fujita; Katsumi Doi; Tateki Kubo; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Anchoring proteins confer G protein sensitivity to an inward-rectifier K(+) channel through the GK domain.
The EMBO journal 2000;19(1):78-83.
2000: A Mammoto; Kiyohisa Takahashi; Takuya Sasaki; Yoshimi Takai
Stimulation of Rho GDI release by ERM proteins.
Methods in enzymology 2000;325():91-101.
1999: Tomoyuki Sumi; Kunihiro Matsumoto; Yoshimi Takai; Tadashi Nakamura
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2.
The Journal of cell biology 1999;147(7):1519-32.
1999: N Ide; Yutaka Hata; H Nishioka; K Hirao; Ikuko Yao; M Deguchi; Akira Mizoguchi; H Nishimori; T Tokino; Y Nakamura; Yoshimi Takai
Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cells.
Oncogene 1999;18(54):7810-5.
1999: Gaku Sakaguchi; T Manabe; K Kobayashi; S Orita; Takuya Sasaki; A Naito; M Maeda; H Igarashi; Goro Katsuura; H Nishioka; A Mizoguchi; Shigeyoshi Itohara; T Takahashi; Yoshimi Takai
Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission.
The European journal of neuroscience 1999;11(12):4262-8.
1999: Tatsuji Fujiwara; Keiichi Tanaka; E Inoue; M Kikyo; Yoshimi Takai
Bni1p regulates microtubule-dependent nuclear migration through the actin cytoskeleton in Saccharomyces cerevisiae.
Molecular and cellular biology 1999;19(12):8016-27.
1999: M Kikyo; Keiichi Tanaka; T Kamei; K Ozaki; Tatsuji Fujiwara; E Inoue; Y Takita; Y Ohya; Yoshimi Takai
An FH domain-containing Bnr1p is a multifunctional protein interacting with a variety of cytoskeletal proteins in Saccharomyces cerevisiae.
Oncogene 1999;18(50):7046-54.
1999: T Kamei; Takashi Matozaki; Toshiaki Sakisaka; A Kodama; Shigeyuki Yokoyama; Ying-Feng Peng; K Nakano; K Takaishi; Yoshimi Takai
Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells--regulation by Rho, Rac and Rab small G proteins.
Oncogene 1999;18(48):6776-84.
1999: Toshihisa Ohtsuka; Yoshio Hata; N Ide; T Yasuda; E Inoue; Tomoyuki Inoue; Akira Mizoguchi; Yoshimi Takai
nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM).
Biochemical and biophysical research communications 1999;265(1):38-44.
1999: Hiroshi Kawabe; Yoshio Hata; Masakazu Takeuchi; N Ide; Akira Mizoguchi; Yoshimi Takai
nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP).
The Journal of biological chemistry 1999;274(43):30914-8.
1999: T Asakura; Hiroyuki Nakanishi; Toshiaki Sakisaka; Kiyohisa Takahashi; Kenji Mandai; M Nishimura; Takuya Sasaki; Yoshimi Takai
Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cells.
Genes to cells : devoted to molecular & cellular mechanisms 1999;4(10):573-81.
1999: Ikuko Yao; Yutaka Hata; K Hirao; M Deguchi; N Ide; M Takeuchi; Yoshimi Takai
Synamon, a novel neuronal protein interacting with synapse-associated protein 90/postsynaptic density-95-associated protein.
The Journal of biological chemistry 1999;274(39):27463-6.
1999: A Togawa; J Miyoshi; H Ishizaki; M Tanaka; A Takakura; H Nishioka; H Yoshida; T Doi; Akira Mizoguchi; N Matsuura; Y Niho; Y Nishimune; S i Nishikawa; Yoshimi Takai
Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha.
Oncogene 1999;18(39):5373-80.
1999: Wataru Ikeda; Hiroyuki Nakanishi; Jun Miyoshi; Kenji Mandai; Hiroyoshi Ishizaki; M Tanaka; A Togawa; Kiyohisa Takahashi; H Nishioka; H Yoshida; Akira Mizoguchi; S Nishikawa; Yoshimi Takai
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis.
The Journal of cell biology 1999;146(5):1117-32.
1999: A Mammoto; T Ohtsuka; I Hotta; Takuya Sasaki; Yoshimi Takai
Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling.
The Journal of biological chemistry 1999;274(36):25517-24.
1999: M Umikawa; H Obaishi; Hiroyuki Nakanishi; K Satoh-Horikawa; Kiyohisa Takahashi; I Hotta; Yoshiharu Matsuura; Yoshimi Takai
Association of frabin with the actin cytoskeleton is essential for microspike formation through activation of Cdc42 small G protein.
The Journal of biological chemistry 1999;274(36):25197-200.
1999: T Kamei; T Matozaki; Yoshimi Takai
[Mechanisms of cell adhesion and migration].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(9):1359-66.
1999: K Nakano; K Takaishi; A Kodama; A Mammoto; H Shiozaki; Morito Monden; Yoshimi Takai
Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells.
Molecular biology of the cell 1999;10(8):2481-91.
1999: A Kodama; K Takaishi; K Nakano; H Nishioka; Yoshimi Takai
Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells.
Oncogene 1999;18(27):3996-4006.
1999: M Irie; Yutaka Hata; M Deguchi; N Ide; K Hirao; Ikuko Yao; H Nishioka; Yoshimi Takai
Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions.
Oncogene 1999;18(18):2811-7.
1999: Kiyohisa Takahashi; Hiroyuki Nakanishi; M Miyahara; Kenji Mandai; K Satoh; Akiko K Satoh; H Nishioka; J Aoki; A Nomoto; Akira Mizoguchi; Yoshimi Takai
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.
The Journal of cell biology 1999;145(3):539-49.
1999: Ikuko Yao; Yutaka Hata; N Ide; K Hirao; M Deguchi; H Nishioka; Akira Mizoguchi; Yoshimi Takai
MAGUIN, a novel neuronal membrane-associated guanylate kinase-interacting protein.
The Journal of biological chemistry 1999;274(17):11889-96.
1999: N Ide; Yutaka Hata; M Deguchi; K Hirao; Ikuko Yao; Yoshimi Takai
Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat protein/delta-catenin.
Biochemical and biophysical research communications 1999;256(3):456-61.
1999: Kenji Mandai; Hiroyuki Nakanishi; Akiko K Satoh; Kiyohisa Takahashi; K Satoh; H Nishioka; Akira Mizoguchi; Yoshimi Takai
Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions.
The Journal of cell biology 1999;144(5):1001-17.
1999: Shigeyuki Yokoyama; H Shirataki; Toshiaki Sakisaka; Yoshimi Takai
Three splicing variants of tomosyn and identification of their syntaxin-binding region.
Biochemical and biophysical research communications 1999;256(1):218-22.
1999: Toshiaki Sakisaka; Hiroyuki Nakanishi; Kiyohisa Takahashi; Kenji Mandai; M Miyahara; Akiko K Satoh; K Takaishi; Yoshimi Takai
Different behavior of l-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction.
Oncogene 1999;18(8):1609-17.
1999: Atsushi Inanobe; Y Yoshimoto; Yoshiyuki Horio; Ken-ichirou Morishige; Hiroshi Hibino; S Matsumoto; Y Tokunaga; Takashi Maeda; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(3):1006-17.
1998: H Oishi; Takuya Sasaki; Fumiko Nagano; Wataru Ikeda; Tomoko Ohya; Masayuki Wada; N Ide; Hiroyuki Nakanishi; Yoshimi Takai
Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis.
The Journal of biological chemistry 1998;273(51):34580-5.
1998: Toshihisa Ohtsuka; Hiroyuki Nakanishi; Wataru Ikeda; Akiko K Satoh; Yumiko Momose; H Nishioka; Yoshimi Takai
Nexilin: a novel actin filament-binding protein localized at cell-matrix adherens junction.
The Journal of cell biology 1998;143(5):1227-38.
1998: Fumiko Nagano; S Orita; Takuya Sasaki; A Naito; Gaku Sakaguchi; M Maeda; T Watanabe; E Kominami; Y Uchiyama; Yoshimi Takai
Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport.
The Journal of biological chemistry 1998;273(46):30065-8.
1998: Akihisa Mino; Keiichi Tanaka; T Kamei; M Umikawa; Tatsuji Fujiwara; Yoshimi Takai
Shs1p: a novel member of septin that interacts with spa2p, involved in polarized growth in saccharomyces cerevisiae.
Biochemical and biophysical research communications 1998;251(3):732-6.
1998: T Kamei; Keiichi Tanaka; T Hihara; M Umikawa; H Imamura; M Kikyo; K Ozaki; Yoshimi Takai
Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1p. Implication in cytokinesis in Saccharomyces cerevisiae.
The Journal of biological chemistry 1998;273(43):28341-5.
1998: M Deguchi; Yutaka Hata; M Takeuchi; N Ide; K Hirao; Ikuko Yao; M Irie; A Toyoda; Yoshimi Takai
BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein.
The Journal of biological chemistry 1998;273(41):26269-72.
1998: Fumiko Nagano; Takuya Sasaki; Kenji Fukui; T Asakura; K Imazumi; Yoshimi Takai
Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.
The Journal of biological chemistry 1998;273(38):24781-5.
1998: Mochida Sumiko; S Orita; Gaku Sakaguchi; T Sasaki; Yoshimi Takai
Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter release process.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11418-22.
1998: Yutaka Hata; H Nakanishi; Yoshimi Takai
Synaptic PDZ domain-containing proteins.
Neuroscience research 1998;32(1):1-7.
1998: Y Ohoka; Yoshimi Takai
Isolation and characterization of cortactin isoforms and a novel cortactin-binding protein, CBP90.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(9):603-12.
1998: H Imamura; K Takaishi; K Nakano; A Kodama; H Oishi; H Shiozaki; Morito Monden; Takuya Sasaki; Yoshimi Takai
Rho and Rab small G proteins coordinately reorganize stress fibers and focal adhesions in MDCK cells.
Molecular biology of the cell 1998;9(9):2561-75.
1998: K Hirao; Yutaka Hata; N Ide; M Takeuchi; M Irie; Ikuko Yao; M Deguchi; A Toyoda; Thomas C Sudhof; Yoshimi Takai
A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteins.
The Journal of biological chemistry 1998;273(33):21105-10.
1998: Gaku Sakaguchi; S Orita; A Naito; M Maeda; H Igarashi; Takuya Sasaki; Yoshimi Takai
A novel brain-specific isoform of beta spectrin: isolation and its interaction with Munc13.
Biochemical and biophysical research communications 1998;248(3):846-51.
1998: H Obaishi; Hiroyuki Nakanishi; Kenji Mandai; K Satoh; Akiko K Satoh; Kiyohisa Takahashi; M Miyahara; H Nishioka; K Takaishi; Yoshimi Takai
Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase.
The Journal of biological chemistry 1998;273(30):18697-700.
1998: Kiyohisa Takahashi; Takuya Sasaki; A Mammoto; I Hotta; K Takaishi; H Imamura; K Nakano; A Kodama; Yoshimi Takai
Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl.
Oncogene 1998;16(25):3279-84.
1998: Y Fujita; H Shirataki; Toshiaki Sakisaka; T Asakura; Tomoko Ohya; H Kotani; Shigeyuki Yokoyama; H Nishioka; Y Matsuura; Akira Mizoguchi; R H Scheller; Yoshimi Takai
Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process.
Neuron 1998;20(5):905-15.
1998: Tatsuji Fujiwara; Keiichi Tanaka; Akihisa Mino; M Kikyo; Kiyohisa Takahashi; Kazuya Shimizu; Yoshimi Takai
Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae.
Molecular biology of the cell 1998;9(5):1221-33.
1998: Takuya Sasaki; Yoshimi Takai
The Rho small G protein family-Rho GDI system as a temporal and spatial determinant for cytoskeletal control.
Biochemical and biophysical research communications 1998;245(3):641-5.
1998: M Umikawa; Keiichi Tanaka; T Kamei; Kazuya Shimizu; H Imamura; Takuya Sasaki; Yoshimi Takai
Interaction of Rho1p target Bni1p with F-actin-binding elongation factor 1alpha: implication in Rho1p-regulated reorganization of the actin cytoskeleton in Saccharomyces cerevisiae.
Oncogene 1998;16(15):2011-6.
1998: Kazuya Shimizu; H Shirataki; Takeshi Honda; S Minami; Yoshimi Takai
Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide.
The Journal of biological chemistry 1998;273(12):6591-4.
1998: N Ide; Yutaka Hata; K Hirao; M Irie; M Deguchi; Ikuko Yao; A Satoh; M Wada; Kiyohisa Takahashi; Hiroyuki Nakanishi; Yoshimi Takai
Interaction of rat lin-10 with brain-enriched F-actin-binding protein, neurabin-II/spinophilin.
Biochemical and biophysical research communications 1998;244(1):258-62.
1998: N Ide; K Hirao; Yutaka Hata; M Takeuchi; M Irie; Ikuko Yao; M Deguchi; A Toyoda; H Nishioka; Akira Mizoguchi; Yoshimi Takai
Molecular cloning and characterization of rat lin-10.
Biochemical and biophysical research communications 1998;243(2):634-8.
1998: Akiko K Satoh; Hiroyuki Nakanishi; H Obaishi; M Wada; Kiyohisa Takahashi; K Satoh; K Hirao; H Nishioka; Yutaka Hata; Akira Mizoguchi; Yoshimi Takai
Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.
The Journal of biological chemistry 1998;273(6):3470-5.
1998: A Mammoto; Takuya Sasaki; T Asakura; I Hotta; H Imamura; Kiyohisa Takahashi; Yoshiharu Matsuura; T Shirao; Yoshimi Takai
Interactions of drebrin and gephyrin with profilin.
Biochemical and biophysical research communications 1998;243(1):86-9.
1998: K Tanaka; Yoshimi Takai
Control of reorganization of the actin cytoskeleton by Rho family small GTP-binding proteins in yeast.
Current opinion in cell biology 1998;10(1):112-6.
1998: T Asakura; Takuya Sasaki; Fumiko Nagano; Akiko K Satoh; H Obaishi; H Nishioka; H Imamura; K Hotta; Keiichi Tanaka; Hiroyuki Nakanishi; Yoshimi Takai
Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae.
Oncogene 1998;16(1):121-30.
1998: Tomoko Ohya; Takuya Sasaki; M Kato; Yoshimi Takai
Involvement of Rabphilin3 in endocytosis through interaction with Rabaptin5.
The Journal of biological chemistry 1998;273(1):613-7.
1998: K Shimizu; T Ohtsuka; Yoshimi Takai
Cell-free assay system for Ras- and Rap1-dependent activation of MAP-kinase cascade.
Methods in molecular biology (Clifton, N.J.) 1998;84():173-83.
1997: K Takaishi; Takuya Sasaki; H Kotani; H Nishioka; Yoshimi Takai
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells.
The Journal of cell biology 1997;139(4):1047-59.
1997: Hiroyuki Nakanishi; H Obaishi; Akiko K Satoh; M Wada; Kenji Mandai; K Satoh; H Nishioka; Y Matsuura; Akira Mizoguchi; Yoshimi Takai
Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation.
The Journal of cell biology 1997;139(4):951-61.
1997: Kenji Mandai; Hiroyuki Nakanishi; Akiko K Satoh; H Obaishi; M Wada; H Nishioka; M Itoh; Akira Mizoguchi; T Aoki; T Fujimoto; Y Matsuda; Shoichiro Tsukita; Yoshimi Takai
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction.
The Journal of cell biology 1997;139(2):517-28.
1997: Kiyohisa Takahashi; Takuya Sasaki; A Mammoto; K Takaishi; T Kameyama; Shoichiro Tsukita; Yoshimi Takai
Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein.
The Journal of biological chemistry 1997;272(37):23371-5.
1997: M Irie; Yutaka Hata; M Takeuchi; K Ichtchenko; A Toyoda; K Hirao; Yoshimi Takai; T W Rosahl; T C Südhof
Binding of neuroligins to PSD-95.
Science (New York, N.Y.) 1997;277(5331):1511-5.
1997: G Koch; Keiichi Tanaka; T Masuda; W Yamochi; H Nonaka; Yoshimi Takai
Association of the Rho family small GTP-binding proteins with Rho GDP dissociation inhibitor (Rho GDI) in Saccharomyces cerevisiae.
Oncogene 1997;15(4):417-22.
1997: T Hihara; Keiichi Tanaka; Yoshimi Takai
[Functions and modes of action of Ras and Rho small GTP-binding proteins].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1501-8.
1997: S Orita; A Naito; Gaku Sakaguchi; M Maeda; H Igarashi; Takuya Sasaki; Yoshimi Takai
Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery.
The Journal of biological chemistry 1997;272(26):16081-4.
1997: Yoshiyuki Horio; Hiroshi Hibino; Atsushi Inanobe; Masashi Yamada; Masaru Ishii; Y Tada; E Satoh; Yoshio Hata; Yoshimi Takai; Yoshihisa Kurachi
Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.
The Journal of biological chemistry 1997;272(20):12885-8.
1997: H Imamura; Keiichi Tanaka; T Hihara; M Umikawa; T Kamei; Kiyohisa Takahashi; Takuya Sasaki; Yoshimi Takai
Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae.
The EMBO journal 1997;16(10):2745-55.
1997: M Takeuchi; Yutaka Hata; K Hirao; A Toyoda; M Irie; Yoshimi Takai
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.
The Journal of biological chemistry 1997;272(18):11943-51.
1997: H Kotani; K Takaishi; Takuya Sasaki; Yoshimi Takai
Rho regulates association of both the ERM family and vinculin with the plasma membrane in MDCK cells.
Oncogene 1997;14(14):1705-13.
1997: Y Jin-no; H Shirataki; T Senbonmatsu; T Yamamoto; Y Fujita; H Nakanishi; Yoshimi Takai
A novel function of the C-terminal lipid moieties of Rab3A small G protein implicated in Ca2+-dependent exocytosis--inhibition of interaction with GTP and reduction of this inhibition by phospholipid.
Genes to cells : devoted to molecular & cellular mechanisms 1997;2(4):273-88.
1997: A Naito; S Orita; Akio Wanaka; Takuya Sasaki; Gaku Sakaguchi; M Maeda; H Igarashi; M Tohyama; Yoshimi Takai
Molecular cloning of mouse Doc2alpha and distribution of its mRNA in adult mouse brain.
Brain research. Molecular brain research 1997;44(2):198-204.
1997: Kenji Fukui; Takuya Sasaki; K Imazumi; Yoshiharu Matsuura; Hiroyuki Nakanishi; Yoshimi Takai
Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins.
The Journal of biological chemistry 1997;272(8):4655-8.
1997: M Wada; Hiroyuki Nakanishi; Akiko K Satoh; H Hirano; H Obaishi; Y Matsuura; Yoshimi Takai
Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins.
The Journal of biological chemistry 1997;272(7):3875-8.
1997: Y Fujita; Yoshimi Takai
[Rab3A and neurotransmitter release].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(3 Suppl):364-70.
1997: Takuya Sasaki; H Shirataki; Hiroyuki Nakanishi; Yoshimi Takai
Rab3A-rabphilin-3A system in neurotransmitter release.
Advances in second messenger and phosphoprotein research 1997;31():279-94.
1996: H Oishi; T Sasaki; Yoshimi Takai
Interaction of both the C2A and C2B domains of rabphilin3 with Ca2+ and phospholipid.
Biochemical and biophysical research communications 1996;229(2):498-503.
1996: M Kato; Takuya Sasaki; Tomoko Ohya; Hiroyuki Nakanishi; H Nishioka; M Imamura; Yoshimi Takai
Physical and functional interaction of rabphilin-3A with alpha-actinin.
The Journal of biological chemistry 1996;271(50):31775-8.
1996: N Masumoto; Takuya Sasaki; Masahiro Tahara; A Mammoto; Yoshihide Ikebuchi; Keiichi Tasaka; M Tokunaga; Yoshimi Takai; A Miyake
Involvement of Rabphilin-3A in cortical granule exocytosis in mouse eggs.
The Journal of cell biology 1996;135(6 Pt 2):1741-7.
1996: H Kohno; K Tanaka; Akihisa Mino; M Umikawa; H Imamura; T Fujiwara; Y Fujita; Kikuko Hotta; H Qadota; T Watanabe; Y Ohya; Yoshimi Takai
Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.
The EMBO journal 1996;15(22):6060-8.
1996: T Senbonmatsu; H Shirataki; Y Jin-no; T Yamamoto; Yoshimi Takai
Interaction of Rabphilin3 with synaptic vesicles through multiple regions.
Biochemical and biophysical research communications 1996;228(2):567-72.
1996: Kazuya Shimizu; H Kawabe; S Minami; Takeshi Honda; K Takaishi; H Shirataki; Yoshimi Takai
SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase.
The Journal of biological chemistry 1996;271(43):27013-7.
1996: R Komuro; Takuya Sasaki; K Takaishi; S Orita; Yoshimi Takai
Involvement of Rho and Rac small G proteins and Rho GDI in Ca2+-dependent exocytosis from PC12 cells.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(10):943-51.
1996: H Imamura; T Hihara; K Tanaka; Yoshimi Takai
[The Rho1 small GTP-binding protein in cell cycle control in Saccharomyces cerevisiae].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(12 Suppl):1891-8.
1996: Kikuko Hotta; K Tanaka; Akihisa Mino; H Kohno; Yoshimi Takai
Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor.
Biochemical and biophysical research communications 1996;225(1):69-74.
1996: H Hirano; K Tanaka; Koichi Ozaki; H Imamura; H Kohno; T Hihara; T Kameyama; Kikuko Hotta; M Arisawa; T Watanabe; H Qadota; Y Ohya; Yoshimi Takai
ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(8):4396-403.
1996: Yoshimi Takai; Takuya Sasaki; H Shirataki; Hiroyuki Nakanishi
Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(7):615-32.
1996: Shun'ichi Kuroda; T Ohtsuka; B Yamamori; Kenji Fukui; Kazuya Shimizu; Yoshimi Takai
Different effects of various phospholipids on Ki-Ras-, Ha-Ras-, and Rap1B-induced B-Raf activation.
The Journal of biological chemistry 1996;271(25):14680-3.
1996: Koichi Ozaki; K Tanaka; H Imamura; T Hihara; T Kameyama; H Nonaka; H Hirano; Y Matsuura; Yoshimi Takai
Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.
The EMBO journal 1996;15(9):2196-207.
1996: Y Fujita; Takuya Sasaki; Kenji Fukui; H Kotani; T Kimura; Yoshio Hata; T C Südhof; R H Scheller; Yoshimi Takai
Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin.
The Journal of biological chemistry 1996;271(13):7265-8.
1996: S Orita; Takuya Sasaki; R Komuro; Gaku Sakaguchi; M Maeda; H Igarashi; Yoshimi Takai
Doc2 enhances Ca2+-dependent exocytosis from PC12 cells.
The Journal of biological chemistry 1996;271(13):7257-60.
1996: Tadatsugu Taniguchi; K Takaishi; T Murayama; M Ito; N Iwata; Kazuo Chihara; Takuya Sasaki; Yoshimi Takai; Toshimitsu Matsui
Cholecystokinin-B/gastrin receptors mediate rapid formation of actin stress fibers.
Oncogene 1996;12(6):1357-60.
1996: S Matsuda; Hiroyuki Nakanishi; Takuya Sasaki; Yoshimi Takai
A membrane-associated GDP/GTP exchange protein specific for Rho small GTP-binding protein - partial purification and characterization from rat brain.
Oncogene 1996;12(4):915-20.
1996: R Komuro; Takuya Sasaki; S Orita; M Maeda; Yoshimi Takai
Involvement of rabphilin-3A in Ca2+-dependent exocytosis from PC12 cells.
Biochemical and biophysical research communications 1996;219(2):435-40.
1996: T Ohtsuka; Kazuya Shimizu; B Yamamori; Shun'ichi Kuroda; Yoshimi Takai
Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein.
The Journal of biological chemistry 1996;271(3):1258-61.
1996: Yuichi Hori; Yoshifumi Takeyama; M Hiroyoshi; Takashi Ueda; A Maeda; H Ohyanagi; Y Saitoh; K Kaibuchi; Yoshimi Takai
Possible involvement of Rab11 p24, a Ras-like small GTP-binding protein, in intracellular vesicular transport of isolated pancreatic acini.
Digestive diseases and sciences 1996;41(1):133-8.
1995: Kiyohisa Takahashi; Takuya Sasaki; Yoshimi Takai
Heterotetramer formation of prenylated Rab3A with two Rabphilin-3A molecules.
Biochemical and biophysical research communications 1995;217(3):979-86.
1995: Gaku Sakaguchi; S Orita; M Maeda; H Igarashi; Yoshimi Takai
Molecular cloning of an isoform of Doc2 having two C2-like domains.
Biochemical and biophysical research communications 1995;217(3):1053-61.
1995: H Nonaka; K Tanaka; H Hirano; T Fujiwara; H Kohno; M Umikawa; Akihisa Mino; Yoshimi Takai
A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae.
The EMBO journal 1995;14(23):5931-8.
1995: N Nishimura; J Goji; H Nakamura; S Orita; Yoshimi Takai; Kimihiko Sano
Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.
Cancer research 1995;55(22):5445-50.
1995: K Takaishi; Takuya Sasaki; T Kameyama; S Tsukita; S Tsukita; Yoshimi Takai
Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.
Oncogene 1995;11(1):39-48.
1995: K Araki; Hiroyuki Nakanishi; H Hirano; M Kato; Takuya Sasaki; Yoshimi Takai
Purification and characterization of Rab GDI beta from rat brain.
Biochemical and biophysical research communications 1995;211(1):296-305.
1995: B Yamamori; Shun'ichi Kuroda; Kazuya Shimizu; Kenji Fukui; T Ohtsuka; Yoshimi Takai
Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins.
The Journal of biological chemistry 1995;270(20):11723-6.
1995: Shun'ichi Kuroda; Kazuya Shimizu; B Yamamori; S Matsuda; K Imazumi; Kozo Kaibuchi; Yoshimi Takai
Purification and characterization of REKS from Xenopus eggs. Identification of REKS as a Ras-dependent mitogen-activated protein kinase kinase kinase.
The Journal of biological chemistry 1995;270(6):2460-5.
1995: S Orita; Takuya Sasaki; A Naito; R Komuro; T Ohtsuka; M Maeda; H Suzuki; H Igarashi; Yoshimi Takai
Doc2: a novel brain protein having two repeated C2-like domains.
Biochemical and biophysical research communications 1995;206(2):439-48.
1995: Takuya Sasaki; Yoshimi Takai
Purification and properties of bovine Rab-GDP dissociation inhibitor.
Methods in enzymology 1995;257():70-9.
1995: Shun'ichi Kuroda; Kazuya Shimizu; B Yamamori; Yoshimi Takai
Cell-free assay system for Ras-dependent MEK activation.
Methods in enzymology 1995;255():257-65.
1995: M Miyazaki; K Kaibuchi; H Shirataki; H Kohno; T Ueyama; J Nishikawa; Yoshimi Takai
Rabphilin-3A binds to a M(r) 115,000 polypeptide in a phosphatidylserine- and Ca(2+)-dependent manner.
Brain research. Molecular brain research 1995;28(1):29-36.
1995: Yoshimi Takai; Kozo Kaibuchi; A Kikuchi; Takuya Sasaki
Effects of prenyl modifications on interactions of small G proteins with regulators.
Methods in enzymology 1995;250():122-33.
1995: K Tanaka; Takuya Sasaki; Yoshimi Takai
Purification and properties of recombinant Rho-GDP dissociation inhibitor.
Methods in enzymology 1995;256():41-9.
1995: K Takaishi; Takuya Sasaki; Yoshimi Takai
Cell motility assay and inhibition by Rho-GDP dissociation inhibitor.
Methods in enzymology 1995;256():336-47.
1995: T Mizuno; Hiroyuki Nakanishi; Yoshimi Takai
Purification and properties of Rac2 from human leukemia cells.
Methods in enzymology 1995;256():15-25.
1994: M Kato; Takuya Sasaki; K Imazumi; Kiyohisa Takahashi; K Araki; H Shirataki; Y Matsuura; A Ishida; H Fujisawa; Yoshimi Takai
Phosphorylation of Rabphilin-3A by calmodulin-dependent protein kinase II.
Biochemical and biophysical research communications 1994;205(3):1776-84.
1994: H Shirataki; T Yamamoto; S Hagi; H Miura; H Oishi; Y Jin-no; T Senbonmatsu; Yoshimi Takai
Rabphilin-3A is associated with synaptic vesicles through a vesicle protein in a manner independent of Rab3A.
The Journal of biological chemistry 1994;269(52):32717-20.
1994: K Imazumi; Takuya Sasaki; Kiyohisa Takahashi; Yoshimi Takai
Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells.
Biochemical and biophysical research communications 1994;205(2):1409-16.
1994: M Miyazaki; H Shirataki; H Kohno; Kozo Kaibuchi; A Tsugita; Yoshimi Takai
Identification as beta-adducin of a protein interacting with rabphilin-3A in the presence of Ca2+ and phosphatidylserine.
Biochemical and biophysical research communications 1994;205(1):460-6.
1994: Y Fujita; Takuya Sasaki; K Araki; Kiyohisa Takahashi; K Imazumi; M Kato; Y Matsuura; Yoshimi Takai
GDP/GTP exchange reaction-stimulating activity of Rabphilin-3A for Rab3A small GTP-binding protein.
FEBS letters 1994;353(1):67-70.
1994: S Numata; H Shirataki; S Hagi; T Yamamoto; Yoshimi Takai
Phosphorylation of Rabphilin-3A, a putative target protein for Rab3A, by cyclic AMP-dependent protein kinase.
Biochemical and biophysical research communications 1994;203(3):1927-34.
1994: Kazuya Shimizu; Shun'ichi Kuroda; B Yamamori; S Matsuda; Kozo Kaibuchi; T Yamauchi; T Isobe; K Irie; K Matsumoto; Yoshimi Takai
Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator.
The Journal of biological chemistry 1994;269(37):22917-20.
1994: A Miyazaki; Takuya Sasaki; K Araki; N Ueno; K Imazumi; Fumiko Nagano; Kiyohisa Takahashi; Yoshimi Takai
Comparison of kinetic properties between MSS4 and Rab3A GRF GDP/GTP exchange proteins.
FEBS letters 1994;350(2-3):333-6.
1994: A Mizoguchi; Y Yano; H Hamaguchi; H Yanagida; C Ide; A Zahraoui; H Shirataki; Takuya Sasaki; Yoshimi Takai
Localization of Rabphilin-3A on the synaptic vesicle.
Biochemical and biophysical research communications 1994;202(3):1235-43.
1994: T Masuda; K Tanaka; H Nonaka; W Yamochi; A Maeda; Yoshimi Takai
Molecular cloning and characterization of yeast rho GDP dissociation inhibitor.
The Journal of biological chemistry 1994;269(31):19713-8.
1994: W Yamochi; K Tanaka; H Nonaka; A Maeda; T Musha; Yoshimi Takai
Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.
The Journal of cell biology 1994;125(5):1077-93.
1994: H Nakanishi; K Kaibuchi; S Orita; N Ueno; Yoshimi Takai
Different functions of Smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25.
The Journal of biological chemistry 1994;269(21):15085-91.
1994: N Nishimura; H Nakamura; Yoshimi Takai; Kimihiko Sano
Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types.
The Journal of biological chemistry 1994;269(19):14191-8.
1994: T Nishiyama; Takuya Sasaki; K Takaishi; M Kato; H Yaku; K Araki; Y Matsuura; Yoshimi Takai
rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.
Molecular and cellular biology 1994;14(4):2447-56.
1994: H Nakanishi; S Orita; K Kaibuchi; K Miura; H Miki; T Takenawa; Yoshimi Takai
Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein.
Biochemical and biophysical research communications 1994;198(3):1255-61.
1994: H Yaku; Takuya Sasaki; Yoshimi Takai
The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: its properties in comparison with those of Smg GDS.
Biochemical and biophysical research communications 1994;198(2):811-7.
1994: K Wada; A Mizoguchi; K Kaibuchi; H Shirataki; C Ide; Yoshimi Takai
Localization of rabphilin-3A, a putative target protein for Rab3A, at the sites of Ca(2+)-dependent exocytosis in PC12 cells.
Biochemical and biophysical research communications 1994;198(1):158-65.
1994: Yoshimi Takai; K Kaibuchi; Takuya Sasaki; K Tanaka; H Shirataki; H Nakanishi
Rho small G protein and cytoskeletal control.
Princess Takamatsu symposia 1994;24():338-50.
1994: K Takaishi; Takuya Sasaki; M Kato; W Yamochi; Shun'ichi Kuroda; T Nakamura; M Takeichi; Yoshimi Takai
Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility.
Oncogene 1994;9(1):273-9.
1994: Yoshimi Takai; K Kaibuchi; Akira Kikuchi; Takuya Sasaki; H Shirataki; K Tanaka
Function and mode of action of small G protein.
Progress in clinical and biological research 1994;390():99-113.
1993: T Yamaguchi; H Shirataki; S Kishida; M Miyazaki; J Nishikawa; K Wada; S Numata; K Kaibuchi; Yoshimi Takai
Two functionally different domains of rabphilin-3A, Rab3A p25/smg p25A-binding and phospholipid- and Ca(2+)-binding domains.
The Journal of biological chemistry 1993;268(36):27164-70.
1993: S Orita; K Kaibuchi; Shun'ichi Kuroda; K Shimizu; H Nakanishi; Yoshimi Takai
Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation.
The Journal of biological chemistry 1993;268(34):25542-6.
1993: Takuya Sasaki; M Kato; Yoshimi Takai
Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.
The Journal of biological chemistry 1993;268(32):23959-63.
1993: S Kishida; H Shirataki; Takuya Sasaki; M Kato; K Kaibuchi; Yoshimi Takai
Rab3A GTPase-activating protein-inhibiting activity of Rabphilin-3A, a putative Rab3A target protein.
The Journal of biological chemistry 1993;268(30):22259-61.
1993: M D Garrett; A K Kabcenell; J E Zahner; K Kaibuchi; Takuya Sasaki; Yoshimi Takai; C M Cheney; Peter Novick
Interaction of Sec4 with GDI proteins from bovine brain, Drosophila melanogaster and Saccharomyces cerevisiae. Conservation of GDI membrane dissociation activity.
FEBS letters 1993;331(3):233-8.
1993: Takuya Sasaki; M Kato; T Nishiyama; Yoshimi Takai
The nucleotide exchange rates of rho and rac small GTP-binding proteins are enhanced to different extents by their regulatory protein Smg GDS.
Biochemical and biophysical research communications 1993;194(3):1188-93.
1993: T Motoike; Kimihiko Sano; H Nakamura; Yoshimi Takai
Expression of smg p25A/rab 3A guanine nucleotide dissociation inhibitor (GDI) in neurons and glial cells from rat brain.
Neuroscience letters 1993;156(1-2):87-90.
1993: K Kishi; K Tanaka; Yoshimi Takai
[Ras p21 and signal transduction].
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(8):1107-21.
1993: H Shirataki; K Kaibuchi; Tsuyoshi Sakoda; S Kishida; T Yamaguchi; K Wada; M Miyazaki; Yoshimi Takai
Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin.
Molecular and cellular biology 1993;13(4):2061-8.
1993: K Kishi; Takuya Sasaki; Shun'ichi Kuroda; T Itoh; Yoshimi Takai
Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).
The Journal of cell biology 1993;120(5):1187-95.
1993: M Kawamura; K Kaibuchi; K Kishi; Yoshimi Takai
Translocation of Ki-ras p21 between membrane and cytoplasm by smg GDS.
Biochemical and biophysical research communications 1993;190(3):832-41.
1993: T Itoh; K Kaibuchi; T Masuda; Toshiyoshi Yamamoto; Y Matsuura; A Maeda; K Shimizu; Yoshimi Takai
The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase.
The Journal of biological chemistry 1993;268(5):3025-8.
1993: T Itoh; K Kaibuchi; T Masuda; Toshiyoshi Yamamoto; Y Matsuura; A Maeda; K Shimizu; Yoshimi Takai
A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(3):975-9.
1993: Y Miura; Akira Kikuchi; T Musha; Shun'ichi Kuroda; H Yaku; Takuya Sasaki; Yoshimi Takai
Regulation of morphology by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in Swiss 3T3 cells.
The Journal of biological chemistry 1993;268(1):510-5.
1993: K Takaishi; Akira Kikuchi; Shun'ichi Kuroda; Ko Kotani; Takuya Sasaki; Yoshimi Takai
Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility.
Molecular and cellular biology 1993;13(1):72-9.
1993: Yoshimi Takai; K Kaibuchi; Akira Kikuchi; Takuya Sasaki; H Shirataki
Regulators of small GTPases.
Ciba Foundation symposium 1993;176():128-38; discussion 138-46.
1992: H Horiuchi; K Kaibuchi; M Kawamura; Y Matsuura; N Suzuki; Y Kuroda; Tohru Kataoka; Yoshimi Takai
The posttranslational processing of ras p21 is critical for its stimulation of yeast adenylate cyclase.
Molecular and cellular biology 1992;12(10):4515-20.
1992: K Kotani; Akira Kikuchi; K Doi; S Kishida; Tsuyoshi Sakoda; K Kishi; Yoshimi Takai
The functional domain of the stimulatory GDP/GTP exchange protein (smg GDS) which interacts with the C-terminal geranylgeranylated region of rap1/Krev-1/smg p21.
Oncogene 1992;7(9):1699-704.
1992: Tsuyoshi Sakoda; K Kaibuchi; K Kishi; S Kishida; K Doi; M Hoshino; S Hattori; Yoshimi Takai
smg/rap1/Krev-1 p21s inhibit the signal pathway to the c-fos promoter/enhancer from c-Ki-ras p21 but not from c-raf-1 kinase in NIH3T3 cells.
Oncogene 1992;7(9):1705-11.
1992: A Mizoguchi; M Arakawa; M Masutani; A Tamekane; H Yamaguchi; N Minami; Yoshimi Takai; C Ide
Localization of smg p25A/rab3A p25, a small GTP-binding protein, at the active zone of the rat neuromuscular junction.
Biochemical and biophysical research communications 1992;186(3):1345-52.
1992: Y Yoshida; M Kawata; Y Miura; T Musha; Takuya Sasaki; Akira Kikuchi; Yoshimi Takai
Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 cells induces DNA synthesis and morphological changes.
Molecular and cellular biology 1992;12(8):3407-14.
1992: Akira Kikuchi; Shun'ichi Kuroda; Takuya Sasaki; Ko Kotani; K i Hirata; M Katayama; Yoshimi Takai
Functional interactions of stimulatory and inhibitory GDP/GTP exchange proteins and their common substrate small GTP-binding protein.
The Journal of biological chemistry 1992;267(21):14611-5.
1992: H Shirataki; K Kaibuchi; T Yamaguchi; K Wada; H Horiuchi; Yoshimi Takai
A possible target protein for smg-25A/rab3A small GTP-binding protein.
The Journal of biological chemistry 1992;267(16):10946-9.
1992: Shun'ichi Kuroda; Akira Kikuchi; K i Hirata; T Masuda; K Kishi; Takuya Sasaki; Yoshimi Takai
Cooperative function of rho GDS and rho GDI to regulate rho p21 activation in smooth muscle.
Biochemical and biophysical research communications 1992;185(1):473-80.
1992: T Mizuno; K Kaibuchi; S Ando; T Musha; K Hiraoka; K Takaishi; M Asada; H Nunoi; I Matsuda; Yoshimi Takai
Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins.
The Journal of biological chemistry 1992;267(15):10215-8.
1992: T Musha; M Kawata; Yoshimi Takai
The geranylgeranyl moiety but not the methyl moiety of the smg-25A/rab3A protein is essential for the interactions with membrane and its inhibitory GDP/GTP exchange protein.
The Journal of biological chemistry 1992;267(14):9821-5.
1992: K i Hirata; Akira Kikuchi; Takuya Sasaki; Shun'ichi Kuroda; K Kaibuchi; Y Matsuura; H Seki; K Saida; Yoshimi Takai
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.
The Journal of biological chemistry 1992;267(13):8719-22.
1992: Y S Kim; Akira Kikuchi; Yoshimi Takai
Effect of chlorpromazine on the smg GDS action.
Biochemical and biophysical research communications 1992;182(3):1446-53.
1992: Y Miura; K Kaibuchi; T Itoh; J D Corbin; S H Francis; Yoshimi Takai
Phosphorylation of smg p21B/rap1B p21 by cyclic GMP-dependent protein kinase.
FEBS letters 1992;297(1-2):171-4.
1992: M Kawata; Yoshimi Takai
[Small GTP-binding protein and platelet function].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(2):230-6.
1992: Akira Kikuchi; K Kaibuchi; Yuichi Hori; H Nonaka; Tsuyoshi Sakoda; M Kawamura; T Mizuno; Yoshimi Takai
Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21.
Oncogene 1992;7(2):289-93.
1992: H Fujioka; K Kaibuchi; K Kishi; Toshiyoshi Yamamoto; M Kawamura; Tsuyoshi Sakoda; T Mizuno; Yoshimi Takai
Transforming and c-fos promoter/enhancer-stimulating activities of a stimulatory GDP/GTP exchange protein for small GTP-binding proteins.
The Journal of biological chemistry 1992;267(2):926-30.
1992: K Matsuda; Choitsu Sakamoto; O Nakano; Y Konda; Takashi Matozaki; K Wada; Masato Kasuga; A Mizoguchi; Akira Kikuchi; Yoshimi Takai
Distribution of smg p25A and smg p21s, ras p21-like guanine nucleotide-binding proteins, in the rat stomach.
The American journal of physiology 1992;262(1 Pt 1):G69-73.
1992: K Kaibuchi; Akira Kikuchi; M Kawata; Yoshimi Takai
The small G protein superfamily--possible functions and modes of action.
Journal of nutritional science and vitaminology 1992;Spec No():275-8.
1991: T Motoike; Kimihiko Sano; Syuichi Tsuneishi; H Nakamura; Y Kushima; H Hatanaka; Yoshimi Takai
Expression and localization of smg p25A (= rab3A) in cultured rat hippocampal cells.
Neuroscience letters 1991;134(1):109-12.
1991: H Shirataki; K Kaibuchi; M Hiroyoshi; M Isomura; S Araki; Takuya Sasaki; Yoshimi Takai
Inhibition of the action of the stimulatory GDP/GTP exchange protein for smg p21 by the geranylgeranylated synthetic peptides designed from its C-terminal region.
The Journal of biological chemistry 1991;266(31):20672-7.
1991: Y Kawahara; M Kawata; M Sunako; S Araki; M Koide; T Tsuda; H Fukuzaki; Yoshimi Takai
Small GTP-binding proteins in bovine aortic smooth muscle.
Japanese circulation journal 1991;55(10):1036-43.
1991: H Horiuchi; M Kawata; M Katayama; Y Yoshida; T Musha; S Ando; Yoshimi Takai
A novel prenyltransferase for a small GTP-binding protein having a C-terminal Cys-Ala-Cys structure.
The Journal of biological chemistry 1991;266(26):16981-4.
1991: T Mizuno; K Kaibuchi; Toshiyoshi Yamamoto; M Kawamura; Tsuyoshi Sakoda; H Fujioka; Y Matsuura; Yoshimi Takai
A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6442-6.
1991: M Katayama; M Kawata; Y Yoshida; H Horiuchi; Toshiyoshi Yamamoto; Y Matsuura; Yoshimi Takai
The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21.
The Journal of biological chemistry 1991;266(19):12639-45.
1991: S Kawamura; K Kaibuchi; M Hiroyoshi; H Fujioka; T Mizuno; Yoshimi Takai
Inhibition of the action of a stimulatory GDP/GTP exchange protein for smg p21 by acidic membrane phospholipids.
Japanese journal of cancer research : Gann 1991;82(7):758-61.
1991: T Itoh; K Kaibuchi; Takuya Sasaki; Yoshimi Takai
The smg GDS-induced activation of smg p21 is initiated by cyclic AMP-dependent protein kinase-catalyzed phosphorylation of smg p21.
Biochemical and biophysical research communications 1991;177(3):1319-24.
1991: Takuya Sasaki; K Kaibuchi; A K Kabcenell; Peter Novick; Yoshimi Takai
A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein.
Molecular and cellular biology 1991;11(5):2909-12.
1991: K Kaibuchi; T Mizuno; H Fujioka; Toshiyoshi Yamamoto; K Kishi; Y Fukumoto; Yuichi Hori; Yoshimi Takai
Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein.
Molecular and cellular biology 1991;11(5):2873-80.
1991: Yuichi Hori; K Kaibuchi; Yoshimi Takai
[Comparison of the mode of action of ras p 21 with those of protein kinase A and C in the gene expression].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1032-6.
1991: M Kawata; Y Kawahara; M Sunako; S Araki; M Koide; T Tsuda; H Fukuzaki; Yoshimi Takai
The molecular heterogeneity of the smg-21/Krev-1/rap1 proteins, a GTP-binding protein having the same effector domain as ras p21s, in bovine aortic smooth muscle membranes.
Oncogene 1991;6(5):841-8.
1991: Y Hata; K Kaibuchi; S Kawamura; M Hiroyoshi; H Shirataki; Yoshimi Takai
Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A-catalyzed phosphorylation of smg p21.
The Journal of biological chemistry 1991;266(10):6571-7.
1991: Yuichi Hori; Akira Kikuchi; M Isomura; M Katayama; Y Miura; H Fujioka; K Kaibuchi; Yoshimi Takai
Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.
Oncogene 1991;6(4):515-22.
1991: Y Yoshida; M Kawata; M Katayama; H Horiuchi; Y Kita; Yoshimi Takai
A geranylgeranyltransferase for rhoA p21 distinct from the farnesyltransferase for ras p21S.
Biochemical and biophysical research communications 1991;175(2):720-8.
1991: S Araki; K Kaibuchi; Takuya Sasaki; Y Hata; Yoshimi Takai
Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein.
Molecular and cellular biology 1991;11(3):1438-47.
1991: K Shimizu; K Kaibuchi; H Nonaka; J Yamamoto; Yoshimi Takai
Tissue and subcellular distributions of an inhibitory GDP/GTP exchange protein (GDI) for the rho proteins by use of its specific antibody.
Biochemical and biophysical research communications 1991;175(1):199-206.
1991: M Hiroyoshi; K Kaibuchi; S Kawamura; Y Hata; Yoshimi Takai
Role of the C-terminal region of smg p21, a ras p21-like small GTP-binding protein, in membrane and smg p21 GDP/GTP exchange protein interactions.
The Journal of biological chemistry 1991;266(5):2962-9.
1991: S Kawamura; K Kaibuchi; M Hiroyoshi; Y Hata; Yoshimi Takai
Stoichiometric interaction of smg p21 with its GDP/GTP exchange protein and its novel action to regulate the translocation of smg p21 between membrane and cytoplasm.
Biochemical and biophysical research communications 1991;174(3):1095-102.
1991: H Nonaka; K Kaibuchi; K Shimizu; J Yamamoto; Yoshimi Takai
Tissue and subcellular distributions of an inhibitory GDP/GTP exchange protein (GDI) for smg p25A by use of its antibody.
Biochemical and biophysical research communications 1991;174(2):556-63.
1991: Takashi Ueda; Y Takeyama; T Ohmori; H Ohyanagi; Y Saitoh; Yoshimi Takai
Purification and characterization from rat liver cytosol of a GDP dissociation inhibitor (GDI) for liver 24K G, a ras p21-like GTP-binding protein, with properties similar to those of smg p25A GDI.
Biochemistry 1991;30(4):909-17.
1991: M Isomura; Akira Kikuchi; N Ohga; Yoshimi Takai
Regulation of binding of rhoB p20 to membranes by its specific regulatory protein, GDP dissociation inhibitor.
Oncogene 1991;6(1):119-24.
1991: Kimihiko Sano; T Motoike; H Nakamura; Y Matsui; Y Teranishi; Yoshimi Takai
Differential expression of the N-myc, c-fos, and smg p25A genes in human neuroblastoma cells during neuronal and Schwannian differentiation.
Brain research. Molecular brain research 1991;9(1-2):149-52.
1991: Yoshimi Takai; K Kaibuchi; Akira Kikuchi; M Kawata; Takuya Sasaki; T Yamamoto
Transforming and c-fos promoter/enhancer-stimulating activities of a GDP/GTP exchange protein for small GTP-binding proteins.
Princess Takamatsu symposia 1991;22():197-204.
1990: T Motoike; Kimihiko Sano; Syuichi Tsuneishi; H Nakamura; Yoshimi Takai
Expression of smg p25A, a ras p21-like small GTP-binding protein, during postnatal development of rat cerebellum.
Brain research. Developmental brain research 1990;57(2):279-89.
1990: Kimihiko Sano; H Nakamura; S Mabuchi; T Tanaka; A Nakagawara; Yoshimi Takai
Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues.
Cancer research 1990;50(22):7242-5.
1990: M Kawata; C C Farnsworth; Y Yoshida; Michael H Gelb; John A Glomset; Yoshimi Takai
Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8960-4.
1990: Toshiyoshi Yamamoto; K Kaibuchi; T Mizuno; M Hiroyoshi; H Shirataki; Yoshimi Takai
Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins.
The Journal of biological chemistry 1990;265(27):16626-34.
1990: Y Fukumoto; K Kaibuchi; Yuichi Hori; H Fujioka; S Araki; Takashi Ueda; Akira Kikuchi; Yoshimi Takai
Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.
Oncogene 1990;5(9):1321-8.
1990: N Oku; K Kaibuchi; Y Fukumoto; Yuichi Hori; H Fujioka; Yoshimi Takai
Comparison of the mode of action of ras p21 with those of protein kinases A and C in the stimulation of gene expression in NIH/3T3 cells.
FEBS letters 1990;269(1):148-52.
1990: S Araki; Akira Kikuchi; Y Hata; M Isomura; Yoshimi Takai
Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.
The Journal of biological chemistry 1990;265(22):13007-15.
1990: M Isomura; M Kawata; Yoshimi Takai
[ras p21/ras p21-like small G proteins and their regulatory proteins].
Nihon rinsho. Japanese journal of clinical medicine 1990;48(8):61-70.
1990: Yoshimi Takai; Akira Kikuchi; M Kawata; K Yamamoto; M Hoshijima
Purification, characterization, and possible functions of small molecular weight GTP-binding proteins.
American journal of hypertension 1990;3(8 Pt 2):220S-223S.
1990: Yuichi Hori; K Kaibuchi; Y Fukumoto; N Oku; Yoshimi Takai
Activation of the serum-response and TPA-response elements by expression of the v-abl protein: comparison of the mode of action of the v-abl protein with those of protein kinase C, cyclic AMP-dependent protein kinase, and the activated c-raf protein.
Oncogene 1990;5(8):1201-6.
1990: Y Kawahara; M Kawata; M Sunako; S Araki; M Koide; T Tsuda; H Fukuzaki; Yoshimi Takai
Identification of a major GTP-binding protein in bovine aortic smooth muscle cytosol as the rhoA gene product.
Biochemical and biophysical research communications 1990;170(2):673-83.
1990: H Nakanishi; Yoshifumi Takeyama; H Ohyanagi; Y Saitoh; Yoshimi Takai
Mode of stimulatory action of deoxycholate in signal transduction system of isolated rat pancreatic acini.
Biochemical and biophysical research communications 1990;170(1):111-8.
1990: A Mizoguchi; S Kim; Takashi Ueda; Akira Kikuchi; H Yorifuji; N Hirokawa; Yoshimi Takai
Localization and subcellular distribution of smg p25A, a ras p21-like GTP-binding protein, in rat brain.
The Journal of biological chemistry 1990;265(20):11872-9.
1990: T Tsuda; Y Kawahara; Yoshimi Takai
[GTP-binding protein and phosphoinositide metabolism].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(10):1741-8.
1990: J Yamamoto; Akira Kikuchi; Takashi Ueda; N Ohga; Yoshimi Takai
A GTPase-activating protein for rhoB p20, a ras p21-like GTP-binding protein--partial purification, characterization and subcellular distribution in rat brain.
Brain research. Molecular brain research 1990;8(2):105-11.
1990: S Araki; Y Kawahara; H Fukuzaki; Yoshimi Takai
Serotonin plays a major role in serum-induced phospholipase C-mediated hydrolysis of phosphoinositides and DNA synthesis in vascular smooth muscle cells.
Atherosclerosis 1990;83(1):29-34.
1990: T Ohmori; Yoshifumi Takeyama; Takashi Ueda; M Hiroyoshi; H Nakanishi; H Ohyanagi; Y Saitoh; Yoshimi Takai
Purification and characterization of a novel GTP-binding protein with a Mr value of 24,000 from rat liver.
Biochemical and biophysical research communications 1990;169(2):816-23.
1990: M Isomura; K Kaibuchi; Toshiyoshi Yamamoto; S Kawamura; M Katayama; Yoshimi Takai
Partial purification and characterization of GDP dissociation stimulator (GDS) for the rho proteins from bovine brain cytosol.
Biochemical and biophysical research communications 1990;169(2):652-9.
1990: Takashi Ueda; Akira Kikuchi; N Ohga; J Yamamoto; Yoshimi Takai
Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.
The Journal of biological chemistry 1990;265(16):9373-80.
1990: S Kim; A Mizoguchi; Akira Kikuchi; Yoshimi Takai
Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s.
Molecular and cellular biology 1990;10(6):2645-52.
1990: H Fujioka; Akira Kikuchi; Y Yoshida; Shun'ichi Kuroda; Yoshimi Takai
A small GTP-binding protein (G protein) recognized by smg p25A GDP dissociation inhibitor (GDI) in human platelet membranes and GDI for this small G protein in human platelet cytosol.
Biochemical and biophysical research communications 1990;168(3):1244-52.
1990: Y Hata; Akira Kikuchi; Takuya Sasaki; Michael D Schaber; Jackson B Gibbs; Yoshimi Takai
Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s.
The Journal of biological chemistry 1990;265(13):7104-7.
1990: K Sano; Yoshimi Takai
[The role of small-molecular-weight GTP-binding protein mechanisms of nerve signal transduction].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(7 Suppl):1004-10.
1990: Takuya Sasaki; Akira Kikuchi; S Araki; Y Hata; M Isomura; Shun'ichi Kuroda; Yoshimi Takai
Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.
The Journal of biological chemistry 1990;265(4):2333-7.
1990: Y Fukumoto; K Kaibuchi; N Oku; Yuichi Hori; Yoshimi Takai
Activation of the c-fos serum-response element by the activated c-Ha-ras protein in a manner independent of protein kinase C and cAMP-dependent protein kinase.
The Journal of biological chemistry 1990;265(2):774-80.
1990: M Sunako; Y Kawahara; K i Hirata; T Tsuda; Mitsuhiro Yokoyama; H Fukuzaki; Yoshimi Takai
Mass analysis of 1,2-diacylglycerol in cultured rabbit vascular smooth muscle cells. Comparison of stimulation by angiotensin II and endothelin.
Hypertension 1990;15(1):84-8.
1990: M Hoshijima; J Kondo; Akira Kikuchi; K Yamamoto; Yoshimi Takai
Purification and characterization from bovine brain membranes of a GTP-binding protein with a Mr of 21,000, ADP-ribosylated by an ADP-ribosyltransferase contaminated in botulinum toxin type C1--identification as the rhoA gene product.
Brain research. Molecular brain research 1990;7(1):9-16.
1989: K Kaibuchi; Y Fukumoto; N Oku; Yuichi Hori; Toshiyoshi Yamamoto; K Toyoshima; Yoshimi Takai
Activation of the serum response element and 12-O-tetradecanoylphorbol-13-acetate response element by the activated c-raf-1 protein in a manner independent of protein kinase C.
The Journal of biological chemistry 1989;264(35):20855-8.
1989: K Yamamoto; T Tanimoto; S Kim; Akira Kikuchi; Yoshimi Takai
Small molecular weight GTP-binding proteins and signal transduction.
Clinica chimica acta; international journal of clinical chemistry 1989;185(3):347-55.
1989: K Kariya; Y Kawahara; S Araki; H Fukuzaki; Yoshimi Takai
Antiproliferative action of cyclic GMP-elevating vasodilators in cultured rabbit aortic smooth muscle cells.
Atherosclerosis 1989;80(2):143-7.
1989: S Kim; Akira Kikuchi; A Mizoguchi; Yoshimi Takai
Intrasynaptosomal distribution of the ras, rho and smg-25A GTP-binding proteins in bovine brain.
Brain research. Molecular brain research 1989;6(2-3):167-76.
1989: M Kawata; Y Kawahara; S Araki; M Sunako; T Tsuda; H Fukuzaki; A Mizoguchi; Yoshimi Takai
Identification of a major GTP-binding protein in bovine aortic smooth muscle membranes as smg p21, a GTP-binding protein having the same effector domain as ras p21s.
Biochemical and biophysical research communications 1989;163(3):1418-27.
1989: N Ohga; Akira Kikuchi; Takashi Ueda; J Yamamoto; Yoshimi Takai
Rabbit intestine contains a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.
Biochemical and biophysical research communications 1989;163(3):1523-33.
1989: Shun'ichi Kuroda; Akira Kikuchi; Yoshimi Takai
Kinetic analysis of the binding of guanine nucleotides to bovine brain rhoB p20, a ras p21-like GTP-binding protein.
Biochemical and biophysical research communications 1989;163(2):674-81.
1989: M Kawata; Akira Kikuchi; M Hoshijima; K Yamamoto; E Hashimoto; Hirohei Yamamura; Yoshimi Takai
Phosphorylation of smg p21, a ras p21-like GTP-binding protein, by cyclic AMP-dependent protein kinase in a cell-free system and in response to prostaglandin E1 in intact human platelets.
The Journal of biological chemistry 1989;264(26):15688-95.
1989: K Kaibuchi; Y Fukumoto; N Oku; Yoshimi Takai; K Arai; M Muramatsu
Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C.
The Journal of biological chemistry 1989;264(23):13489-96.
1989: A Mizoguchi; S Kim; Takashi Ueda; Yoshimi Takai
Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody.
Biochemical and biophysical research communications 1989;162(3):1438-45.
1989: M Adachi; R Ryo; A Yoshida; K Teshigawara; N Yamaguchi; M Hoshijima; Yoshimi Takai; T Sato
Elevation of intracellular calcium ion by prostaglandin E1 and its inhibition by protein kinase C in a human megakaryocyte leukemia cell line.
Cancer research 1989;49(14):3805-8.
1989: I Shoji; Akira Kikuchi; Shun'ichi Kuroda; Yoshimi Takai
Kinetic analysis of the binding of guanine nucleotide to bovine brain smg p25A.
Biochemical and biophysical research communications 1989;162(1):273-81.
1989: Ken-Ichi Kariya; Y Kawahara; H Fukuzaki; M Hagiwara; H Hidaka; Y Fukumoto; Yoshimi Takai
Two types of protein kinase C with different functions in cultured rabbit aortic smooth muscle cells.
Biochemical and biophysical research communications 1989;161(3):1020-7.
1989: Akira Kikuchi; Takuya Sasaki; S Araki; Y Hata; Yoshimi Takai
Purification and characterization from bovine brain cytosol of two GTPase-activating proteins specific for smg p21, a GTP-binding protein having the same effector domain as c-ras p21s.
The Journal of biological chemistry 1989;264(16):9133-6.
1989: H Kosaka; Masato Ogata; I Hikita; S Maruo; S Sugihara; H Matsubara; Yoshimi Takai; Toshiyuki Hamaoka; Hiromi Fujiwara
Model for clonal elimination in the thymus.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3773-7.
1989: M Sunako; Y Kawahara; Ken-Ichi Kariya; S Araki; H Fukuzaki; Yoshimi Takai
Endothelin-induced biphasic formation of 1,2-diacylglycerol in cultured rabbit vascular smooth muscle cells--mass analysis with a radioenzymatic assay.
Biochemical and biophysical research communications 1989;160(2):744-50.
1989: Takashi Ueda; Akira Kikuchi; N Ohga; J Yamamoto; Yoshimi Takai
GTPase activating proteins for the smg-21 GTP-binding protein having the same effector domain as the ras proteins in human platelets.
Biochemical and biophysical research communications 1989;159(3):1411-9.
1989: S Araki; Y Kawahara; Ken-Ichi Kariya; M Sunako; H Fukuzaki; Yoshimi Takai
Stimulation of phospholipase C-mediated hydrolysis of phosphoinositides by endothelin in cultured rabbit aortic smooth muscle cells.
Biochemical and biophysical research communications 1989;159(3):1072-9.
1989: Yoshimi Takai; Akira Kikuchi
[ras p21-like small MW GTP-binding proteins in transmembrane signaling].
Gan to kagaku ryoho. Cancer & chemotherapy 1989;16(3 Pt 2):499-508.
1989: Kimihiko Sano; Akira Kikuchi; Y Matsui; Y Teranishi; Yoshimi Takai
Tissue-specific expression of a novel GTP-binding protein (smg p25A) mRNA and its increase by nerve growth factor and cyclic AMP in rat pheochromocytoma PC-12 cells.
Biochemical and biophysical research communications 1989;158(2):377-85.
1989: T Ohmori; Akira Kikuchi; K Yamamoto; S Kim; Yoshimi Takai
Small molecular weight GTP-binding proteins in human platelet membranes. Purification and characterization of a novel GTP-binding protein with a molecular weight of 22,000.
The Journal of biological chemistry 1989;264(3):1877-81.
1989: A Mizoguchi; Takashi Ueda; K Ikeda; H Shiku; H Mizoguti; Yoshimi Takai
Localization and subcellular distribution of cellular ras gene products in rat brain.
Brain research. Molecular brain research 1989;5(1):31-44.
1988: M Hoshijima; Akira Kikuchi; M Kawata; T Ohmori; E Hashimoto; Hirohei Yamamura; Yoshimi Takai
Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products.
Biochemical and biophysical research communications 1988;157(3):851-60.
1988: T Ohmori; Akira Kikuchi; K Yamamoto; M Kawata; J Kondo; Yoshimi Takai
Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products.
Biochemical and biophysical research communications 1988;157(2):670-6.
1988: M Kawata; Y Matsui; J Kondo; T Hishida; Y Teranishi; Yoshimi Takai
A novel small molecular weight GTP-binding protein with the same putative effector domain as the ras proteins in bovine brain membranes. Purification, determination of primary structure, and characterization.
The Journal of biological chemistry 1988;263(35):18965-71.
1988: Y Hamamori; M Hoshijima; T Ohmori; Takashi Ueda; Yoshimi Takai
Serotonin as a major serum factor inducing the phospholipase C-mediated hydrolysis of phosphoinositides in normal rat kidney cells.
Cancer research 1988;48(23):6697-702.
1988: Y Fukumoto; Y Kawahara; Ken-Ichi Kariya; S Araki; H Fukuzaki; Yoshimi Takai
Independent inhibition of DNA synthesis by protein kinase C, cyclic AMP and interferon alpha/beta in rabbit aortic smooth muscle cells.
Biochemical and biophysical research communications 1988;157(1):337-45.
1988: T Yamashita; K Yamamoto; Akira Kikuchi; M Kawata; J Kondo; T Hishida; Y Teranishi; H Shiku; Yoshimi Takai
Purification and characterization of c-Ki-ras p21 from bovine brain crude membranes.
The Journal of biological chemistry 1988;263(32):17181-8.
1988: Akira Kikuchi; K Yamamoto; Tsuyoshi Fujita; Yoshimi Takai
ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1.
The Journal of biological chemistry 1988;263(31):16303-8.
1988: K Ikeda; Akira Kikuchi; Yoshimi Takai
Small molecular weight GTP-binding proteins in human erythrocyte ghosts.
Biochemical and biophysical research communications 1988;156(2):889-97.
1988: Y Kawahara; Ken-Ichi Kariya; S Araki; H Fukuzaki; Yoshimi Takai
Platelet-derived growth factor (PDGF)-induced phospholipase C-mediated hydrolysis of phosphoinositides in vascular smooth muscle cells--different sensitivity of PDGF- and angiotensin II-induced phospholipase C reactions to protein kinase C-activating phorbol esters.
Biochemical and biophysical research communications 1988;156(2):846-54.
1988: K Yamamoto; S Kim; Akira Kikuchi; Yoshimi Takai
Multiple small molecular weight GTP-binding proteins in bovine brain cytosol. Purification and characterization of a 24KDa protein.
Biochemical and biophysical research communications 1988;155(3):1284-92.
1988: Y Matsui; Akira Kikuchi; J Kondo; T Hishida; Y Teranishi; Yoshimi Takai
Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain.
The Journal of biological chemistry 1988;263(23):11071-4.
1988: H Nakanishi; H Ohyanagi; Yoshifumi Takeyama; Hirohiko Onoyama; Y Saitoh; Akira Kikuchi; Yoshimi Takai
Mode of inhibitory action of cholecystokinin in amylase release from isolated rat pancreatic acini--inhibition of secretory process post to protein kinase C-calcium ion systems.
Biochemical and biophysical research communications 1988;154(3):1314-22.
1988: K Yamamoto; J Kondo; T Hishida; Y Teranishi; Yoshimi Takai
Purification and characterization of a GTP-binding protein with a molecular weight of 20,000 in bovine brain membranes. Identification as the rho gene product.
The Journal of biological chemistry 1988;263(20):9926-32.
1988: T Yamamoto; T Tsuda; Y Hamamori; N Nishimura; Yoshimi Takai
Inhibition of DNA synthesis by protein kinase C-activating phorbol esters in NIH/3T3 cells.
Journal of biochemistry 1988;104(1):53-6.
1988: T Tsuda; Y Kawahara; Y Fukumoto; Yoshimi Takai; H Fukuzaki
Stimulation of phospholipase C-mediated hydrolysis of phosphoinositides by adenosine 5'-triphosphate via P2-purinoceptors in cultured rat aortic vascular smooth muscle cells.
Japanese circulation journal 1988;52(6):570-9.
1988: Y Katakami; Y Nakao; N Katakami; T Koizumi; R Ogawa; H Yamada; Yoshimi Takai; Tsuyoshi Fujita
Cooperative effects of tumor necrosis factor-alpha and 1,25-dihydroxyvitamin D3 on growth inhibition, differentiation, and c-myc reduction in human promyelocytic leukemia cell line HL-60.
Biochemical and biophysical research communications 1988;152(3):1151-7.
1988: M Hoshijima; Takashi Ueda; Y Hamamori; T Ohmori; Yoshimi Takai
Different sensitivity to phorbol esters and pertussis toxin of bombesin- and platelet-derived growth factor-induced, phospholipase C-mediated hydrolysis of phosphoinositides in NIH/3T3 cells.
Biochemical and biophysical research communications 1988;152(1):285-93.
1988: Akira Kikuchi; T Yamashita; M Kawata; K Yamamoto; K Ikeda; T Tanimoto; Yoshimi Takai
Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes.
The Journal of biological chemistry 1988;263(6):2897-904.
1988: Y Kawahara; M Sunako; T Tsuda; H Fukuzaki; Y Fukumoto; Yoshimi Takai
Angiotensin II induces expression of the c-fos gene through protein kinase C activation and calcium ion mobilization in cultured vascular smooth muscle cells.
Biochemical and biophysical research communications 1988;150(1):52-9.
1988: T Tanimoto; M Hoshijima; M Kawata; K Yamamoto; T Ohmori; H Shiku; H Nakano; Yoshimi Takai
Binding of ras p21 to bands 4.2 and 6 of human erythrocyte membranes.
FEBS letters 1988;226(2):291-6.
1988: Hiromi Fujiwara; M Ogata; Y Mizushima; H Kosaka; H Matsubara; Yoshimi Takai; Toshiyuki Hamaoka
Thymic stroma-derived T cell growth factor: its role in the growth of immature thymocytes and T cell repertoire selection.
Princess Takamatsu symposia 1988;19():115-26.
1987: T Tsuda; Y Fukumoto; Y Hamamori; T Yamashita; Yoshimi Takai
Involvement of two intracellular messenger systems, protein kinase C and cyclic AMP, in the regulation of c-fos gene expression in human promyelocytic leukemia (HL-60) cells.
Journal of biochemistry 1987;102(6):1579-83.
1987: Ken-Ichi Kariya; Y Fukumoto; T Tsuda; T Yamamoto; Y Kawahara; H Fukuzaki; Yoshimi Takai
Antiproliferative action of protein kinase C in cultured rabbit aortic smooth muscle cells.
Experimental cell research 1987;173(2):504-14.