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Kazufumi Takano

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Protein Denaturation

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Co-Publications
Name
49
Kanaya, Shigenori
36
Koga, Yuichi
28
Matsumura, Hiroyoshi
25
Yutani, Katsuhide
23
Yamagata, Yuriko
15
Chon, Hyongi
12
Morikawa, Masaaki
10
Mori, Yusuke
10
Adachi, Hiroaki
10
Funahashi, Jun
9
Haruki, Mitsuru
9
Inoue, Tsuyoshi
9
You, Dong-Ju
7
Sasaki, Takatomo
6
Tadokoro, Takashi

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Publications

TOP 3
Tanaka Shun-ichi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin.
Budiman Cahyo; Bando Keisuke; Angkawidjaja Clement; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase. Importance of a V-shaped dimeric structure for binding to protein substrate.
Rohman Muhammad S; Tadokoro Takashi; Angkawidjaja Clement; Abe Yumi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses.

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All Publications

2009: Tanaka Shun-ichi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin.
Journal of molecular biology 2009;394(2):306-19.
2009: Budiman Cahyo; Bando Keisuke; Angkawidjaja Clement; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase. Importance of a V-shaped dimeric structure for binding to protein substrate.
The FEBS journal 2009;276(15):4091-101.
2009: Rohman Muhammad S; Tadokoro Takashi; Angkawidjaja Clement; Abe Yumi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses.
The FEBS journal 2009;276(2):603-13.
2008: Mima Masashi; Kawai Chika; Paku Kumsun; Tomoo Koji; Ishida Toshimasa; Sugiyama Shigeru; Matsumura Hiroyoshi; Kitatani Tomoya; Yoshikawa Hiroshi Y; Maki Syou; Adachi Hiroaki; Takano Kazufumi; Murakami Satoshi; Inoue Tsuyoshi; Mori Yusuke; Kita Satomi; Iwamoto Takahiro
Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 12):1125-7.
2008: Matsumura Hiroyoshi; Adachi Motoyasu; Sugiyama Shigeru; Okada Shino; Yamakami Megumi; Tamada Taro; Hidaka Koushi; Hayashi Yoshio; Kimura Tooru; Kiso Yoshiaki; Kitatani Tomoya; Maki Sho; Yoshikawa Hiroshi Y; Adachi Hiroaki; Takano Kazufumi; Murakami Satoshi; Inoue Tsuyoshi; Kuroki Ryota; Mori Yusuke
Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 11):1003-6.
2008: Tanaka Shun-ichi; Takeuchi Yuki; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of folding.
FEBS letters 2008;582(28):3875-8.
2008: Sugiyama Shigeru; Nomura Yusuke; Sakamoto Taiichi; Kitatani Tomoya; Kobayashi Asako; Miyakawa Shin; Takahashi Yoshinori; Adachi Hiroaki; Takano Kazufumi; Murakami Satoshi; Inoue Tsuyoshi; Mori Yusuke; Nakamura Yoshikazu; Matsumura Hiroyoshi
Crystallization and preliminary X-ray diffraction studies of an RNA aptamer in complex with the human IgG Fc fragment.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 10):942-4.
2008: Rohman Muhammad S; Koga Yuichi; Takano Kazufumi; Chon Hyongi; Crouch Robert J; Kanaya Shigenori
Effect of the disease-causing mutations identified in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII.
The FEBS journal 2008;275(19):4836-49.
2008: Tadokoro Takashi; Matsushita Kyoko; Abe Yumi; Rohman Muhammad Saifur; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Remarkable stabilization of a psychrotrophic RNase HI by a combination of thermostabilizing mutations identified by the suppressor mutation method.
Biochemistry 2008;47(31):8040-7.
2008: Koga Yuichi; Katsumi Ryota; You Dong-Ju; Matsumura Hiroyoshi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of highly thermostable glycerol kinase from a hyperthermophilic archaeon in a dimeric form.
The FEBS journal 2008;275(10):2632-43.
2008: Maki S; Murai R; Yoshikawa H Y; Kitatani T; Nakata S; Kawahara H; Hasenaka H; Kobayashi A; Okada S; Sugiyama S; Adachi H; Matsumura H; Takano K; Murakami S; Inoue T; Sasaki T; Mori Y
Protein crystallization in a 100 nl solution with new stirring equipment.
Journal of synchrotron radiation 2008;15(Pt 3):269-72.
2008: Dong Hongju; Mukaiyama Atsushi; Tadokoro Takashi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Hydrophobic effect on the stability and folding of a hyperthermophilic protein.
Journal of molecular biology 2008;378(1):264-72.
2008: Mukaiyama Atsushi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Osmolyte effect on the stability and folding of a hyperthermophilic protein.
Proteins 2008;71(1):110-8.
2007: Pulido Marian A; Tanaka Shun-ichi; Sringiew Chutima; You Dong-Ju; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Requirement of left-handed glycine residue for high stability of the Tk-subtilisin propeptide as revealed by mutational and crystallographic analyses.
Journal of molecular biology 2007;374(5):1359-73.
2007: Angkawidjaja Clement; You Dong-ju; Matsumura Hiroyoshi; Kuwahara Katsumasa; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation.
FEBS letters 2007;581(26):5060-4.
2007: You Dong-Ju; Chon Hyongi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of type 1 ribonuclease H from hyperthermophilic archaeon Sulfolobus tokodaii: role of arginine 118 and C-terminal anchoring.
Biochemistry 2007;46(41):11494-503.
2007: You Dong-Ju; Fukuchi Satoshi; Nishikawa Ken; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Protein thermostabilization requires a fine-tuned placement of surface-charged residues.
Journal of biochemistry 2007;142(4):507-16.
2007: Tanaka Shun-Ichi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Four new crystal structures of Tk-subtilisin in unautoprocessed, autoprocessed and mature forms: insight into structural changes during maturation.
Journal of molecular biology 2007;372(4):1055-69.
2007: Takano Kazufumi; Katagiri Yoshiaki; Mukaiyama Atsushi; Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Kanaya Shigenori
Conformational contagion in a protein: structural properties of a chameleon sequence.
Proteins 2007;68(3):617-25.
2007: Tadokoro Takashi; Chon Hyongi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Identification of the gene encoding a type 1 RNase H with an N-terminal double-stranded RNA binding domain from a psychrotrophic bacterium.
The FEBS journal 2007;274(14):3715-27.
2007: Tadokoro Takashi; You Dong-Ju; Abe Yumi; Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Structural, thermodynamic, and mutational analyses of a psychrotrophic RNase HI.
Biochemistry 2007;46(25):7460-8.
2007: Pulido M A; Koga Y; Takano K; Kanaya S
Directed evolution of Tk-subtilisin from a hyperthermophilic archaeon: identification of a single amino acid substitution responsible for low-temperature adaptation.
Protein engineering, design & selection : PEDS 2007;20(3):143-53.
2007: Angkawidjaja Clement; You Dong-Ju; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Extracellular overproduction and preliminary crystallographic analysis of a family I.3 lipase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 3):187-9.
2007: Tanaka Shun-ichi; Saito Kenji; Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced folding.
The Journal of biological chemistry 2007;282(11):8246-55.
2007: Katsumi Ryota; Koga Yuichi; You Dong-Ju; Matsumura Hiroyoshi; Takano Kazufumi; Kanaya Shigenori
Crystallization and preliminary X-ray diffraction study of glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakaraensis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 2):126-9.
2007: Hirano Shin-ichi; Morikawa Masaaki; Takano Kazufumi; Imanaka Tadayuki; Kanaya Shigenori
Gentisate 1,2-dioxygenase from Xanthobacter polyaromaticivorans 127W.
Bioscience, biotechnology, and biochemistry 2007;71(1):192-9.
2006: Kashii Masafumi; Fujisawa Ryo; Adachi Hiroaki; Mori Yusuke; Sasaki Takatomo; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori; Matsumura Hiroyoshi; Inoue Tsuyoshi; Murakami Satoshi; Sugamoto Kazuomi; Yoshikawa Hideki
Application of femtosecond laser ablation for detaching grown protein crystals from glass capillary tube.
Journal of bioscience and bioengineering 2006;102(4):372-4.
2006: Mukaiyama Atsushi; Haruki Mitsuru; Ota Motonori; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
A hyperthermophilic protein acquires function at the cost of stability.
Biochemistry 2006;45(42):12673-9.
2006: Tanaka Shun-ichi; Saito Kenji; Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeon.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 9):902-5.
2006: Morikawa Masaaki; Kagihiro Shinji; Haruki Mitsuru; Takano Kazufumi; Branda Steve; Kolter Roberto; Kanaya Shigenori
Biofilm formation by a Bacillus subtilis strain that produces gamma-polyglutamate.
Microbiology (Reading, England) 2006;152(Pt 9):2801-7.
2006: You Dong Ju; Chon Hyongi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 8):781-4.
2006: Angkawidjaja C; Kuwahara K; Omori K; Koga Y; Takano K; Kanaya S
Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization.
Protein engineering, design & selection : PEDS 2006;19(7):337-43.
2006: Pulido Marian; Saito Kenji; Tanaka Shun-Ichi; Koga Yuichi; Morikawa Masaaki; Takano Kazufumi; Kanaya Shigenori
Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its folding.
Applied and environmental microbiology 2006;72(6):4154-62.
2006: Chon Hyongi; Tadokoro Takashi; Ohtani Naoto; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Identification of RNase HII from psychrotrophic bacterium, Shewanella sp. SIB1 as a high-activity type RNase H.
The FEBS journal 2006;273(10):2264-75.
2006: Cornista Joel C; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Amyloidogenecity and pitrilysin sensitivity of a lysine-free derivative of amyloid beta-peptide cleaved from a recombinant fusion protein.
Journal of biotechnology 2006;122(2):186-97.
2006: Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus.
Journal of molecular biology 2006;356(1):165-78.
2006: Hirano Shin-Ichi; Haruki Mitsuru; Takano Kazufumi; Imanaka Tadayuki; Morikawa Masaaki; Kanaya Shigenori
Gene cloning and in vivo characterization of a dibenzothiophene dioxygenase from Xanthobacter polyaromaticivorans.
Applied microbiology and biotechnology 2006;69(6):672-81.
2006: Adachi Hiroaki; Niino Ai; Kinoshita Takayoshi; Warizaya Masaichi; Maruki Riyo; Takano Kazufumi; Matsumura Hiroyoshi; Inoue Tsuyoshi; Murakami Satoshi; Mori Yusuke; Sasaki Takatomo
Solution-stirring method improves crystal quality of human triosephosphate isomerase.
Journal of bioscience and bioengineering 2006;101(1):83-6.
2006: Takano Kazufumi; Endo Shuji; Mukaiyama Atsushi; Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Kanaya Shigenori
Structure of amyloid beta fragments in aqueous environments.
The FEBS journal 2006;273(1):150-8.
2005: Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystal structure of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3 at 2.20 A resolution.
Proteins 2005;61(3):685-8.
2005: Suzuki Yutaka; Win Ohnmar Ye; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Binding analysis of a psychrotrophic FKBP22 to a folding intermediate of protein using surface plasmon resonance.
FEBS letters 2005;579(25):5781-4.
2005: Angkawidjaja Clement; Paul Aditya; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Importance of a repetitive nine-residue sequence motif for intracellular stability and functional structure of a family I.3 lipase.
FEBS letters 2005;579(21):4707-12.
2005: Kitano Hiroshi; Murakami Satoshi; Adachi Hiroaki; Matsumura Hiroyoshi; Takano Kazufumi; Inoue Tsuyoshi; Mori Yusuke; Doi Masaaki; Sasaki Takatomo
Processing of membrane protein crystal using ultraviolet laser irradiation.
Journal of bioscience and bioengineering 2005;100(1):50-3.
2005: Adachi Hiroaki; Takano Kazufumi; Niino Ai; Matsumura Hiroyoshi; Kinoshita Takayoshi; Warizaya Masaichi; Inoue Tsuyoshi; Mori Yusuke; Sasaki Takatomo
Solution stirring initiates nucleation and improves the quality of adenosine deaminase crystals.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 6):759-62.
2005: Chon Hyongi; Matsumura Hiroyoshi; Shimizu Shoko; Maeda Nao; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Overproduction and preliminary crystallographic study of a human kynurenine aminotransferase II homologue from Pyrococcus horikoshii OT3.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 3):319-22.
2005: Chon Hyongi; Matsumura Hiroyoshi; Koga Yuichi; Takano Kazufumi; Kanaya Shigenori
Crystallization and preliminary X-ray diffraction study of thermostable RNase HIII from Bacillus stearothermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 3):293-5.
2005: Suzuki Yutaka; Mizutani Yoichi; Tsuji Tadao; Ohtani Naoto; Takano Kazufumi; Haruki Mitsuru; Morikawa Masaaki; Kanaya Shigenori
Gene cloning, overproduction, and characterization of thermolabile alkaline phosphatase from a psychrotrophic bacterium.
Bioscience, biotechnology, and biochemistry 2005;69(2):364-73.
2005: Suzuki Yutaka; Takano Kazufumi; Kanaya Shigenori
Stabilities and activities of the N- and C-domains of FKBP22 from a psychrotrophic bacterium overproduced in Escherichia coli.
The FEBS journal 2005;272(3):632-42.
2005: Tsunaka Yasuo; Takano Kazufumi; Matsumura Hiroyoshi; Yamagata Yuriko; Kanaya Shigenori
Identification of single Mn(2+) binding sites required for activation of the mutant proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray crystallography.
Journal of molecular biology 2005;345(5):1171-83.
2005: Kunihiro Namio; Haruki Mitsuru; Takano Kazufumi; Morikawa Masaaki; Kanaya Shigenori
Isolation and characterization of Rhodococcus sp. strains TMP2 and T12 that degrade 2,6,10,14-tetramethylpentadecane (pristane) at moderately low temperatures.
Journal of biotechnology 2005;115(2):129-36.
2004: Mukaiyama Atsushi; Takano Kazufumi; Haruki Mitsuru; Morikawa Masaaki; Kanaya Shigenori
Kinetically robust monomeric protein from a hyperthermophile.
Biochemistry 2004;43(43):13859-66.
2004: Chon Hyongi; Nakano Rikita; Ohtani Naoto; Haruki Mitsuru; Takano Kazufumi; Morikawa Masaaki; Kanaya Shigenori
Gene cloning and biochemical characterizations of thermostable ribonuclease HIII from Bacillus stearothermophilus.
Bioscience, biotechnology, and biochemistry 2004;68(10):2138-47.
2004: Cornista Joel; Ikeuchi Satoshi; Haruki Mitsuru; Kohara Atsuko; Takano Kazufumi; Morikawa Masaaki; Kanaya Shigenori
Cleavage of various peptides with pitrilysin from Escherichia coli: kinetic analyses using beta-endorphin and its derivatives.
Bioscience, biotechnology, and biochemistry 2004;68(10):2128-37.
2004: Takano Kazufumi; Saito Minoru; Morikawa Masaaki; Kanaya Shigenori
Mutational and structural-based analyses of the osmolyte effect on protein stability.
Journal of biochemistry 2004;135(6):701-8.
2004: Suzuki Yutaka; Haruki Mitsuru; Takano Kazufumi; Morikawa Masaaki; Kanaya Shigenori
Possible involvement of an FKBP family member protein from a psychrotrophic bacterium Shewanella sp. SIB1 in cold-adaptation.
European journal of biochemistry / FEBS 2004;271(7):1372-81.
2004: Adachi Hiroaki; Takano Kazufumi; Matsumura Hiroyoshi; Inoue Tsuyoshi; Mori Yusuke; Sasaki Takatomo
Protein crystal growth with a two-liquid system and stirring solution.
Journal of synchrotron radiation 2004;11(Pt 1):121-4.
2003: Takano Kazufumi; Scholtz J Martin; Sacchettini James C; Pace C Nick
The contribution of polar group burial to protein stability is strongly context-dependent.
The Journal of biological chemistry 2003;278(34):31790-5.
2003: Takano Kazufumi; Yamagata Yuriko; Yutani Katsuhide
Buried water molecules contribute to the conformational stability of a protein.
Protein engineering 2003;16(1):5-9.
2003: Adachi Hiroaki; Takano Kazufumi; Morikawa Masaaki; Kanaya Shigenori; Yoshimura Masashi; Mori Yusuke; Sasaki Takatomo
Application of a two-liquid system to sitting-drop vapour-diffusion protein crystallization.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 1):194-6.
2002: Goda Shuichiro; Takano Kazufumi; Yamagata Yuriko; Maki Saori; Namba Keiichi; Yutani Katsuhide
Elongation in a beta-structure promotes amyloid-like fibril formation of human lysozyme.
Journal of biochemistry 2002;132(4):655-61.
2002: Funahashi Jun; Takano Kazufumi; Yamagata Yuriko; Yutani Katsuhide
Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
The Journal of biological chemistry 2002;277(24):21792-800.
2001: Takano K; Yamagata Y; Yutani K
Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein.
Proteins 2001;45(3):274-80.
2001: Takano K; Yutani K
A new scale for side-chain contribution to protein stability based on the empirical stability analysis of mutant proteins.
Protein engineering 2001;14(8):525-8.
2001: Takano K; Yamagata Y; Yutani K
Role of non-glycine residues in left-handed helical conformation for the conformational stability of human lysozyme.
Proteins 2001;44(3):233-43.
2001: Takano K; Yamagata Y; Yutani K
Contribution of polar groups in the interior of a protein to the conformational stability.
Biochemistry 2001;40(15):4853-8.
2001: Funahashi J; Takano K; Yutani K
Are the parameters of various stabilization factors estimated from mutant human lysozymes compatible with other proteins?
Protein engineering 2001;14(2):127-34.
2001: Takano K; Funahashi J; Yutani K
The stability and folding process of amyloidogenic mutant human lysozymes.
European journal of biochemistry / FEBS 2001;268(1):155-9.
2000: Funahashi J; Takano K; Yamagata Y; Yutani K
Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry 2000;39(47):14448-56.
2000: Takano K; Tsuchimori K; Yamagata Y; Yutani K
Contribution of salt bridges near the surface of a protein to the conformational stability.
Biochemistry 2000;39(40):12375-81.
2000: Takano K; Yamagata Y; Yutani K
Role of amino acid residues at turns in the conformational stability and folding of human lysozyme.
Biochemistry 2000;39(29):8655-65.
2000: Goda S; Takano K; Yamagata Y; Katakura Y; Yutani K
Effect of extra N-terminal residues on the stability and folding of human lysozyme expressed in Pichia pastoris.
Protein engineering 2000;13(4):299-307.
2000: Goda S; Takano K; Yamagata Y; Nagata R; Akutsu H; Maki S; Namba K; Yutani K
Amyloid protofilament formation of hen egg lysozyme in highly concentrated ethanol solution.
Protein science : a publication of the Protein Society 2000;9(2):369-75.
1999: Takano K; Tsuchimori K; Yamagata Y; Yutani K
Effect of foreign N-terminal residues on the conformational stability of human lysozyme.
European journal of biochemistry / FEBS 1999;266(2):675-82.
1999: Funahashi J; Takano K; Yamagata Y; Yutani K
Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme.
Protein engineering 1999;12(10):841-50.
1999: Takano K; Yamagata Y; Funahashi J; Hioki Y; Kuramitsu S; Yutani K
Contribution of intra- and intermolecular hydrogen bonds to the conformational stability of human lysozyme(,).
Biochemistry 1999;38(39):12698-708.
1999: Takano K; Ota M; Ogasahara K; Yamagata Y; Nishikawa K; Yutani K
Experimental verification of the 'stability profile of mutant protein' (SPMP) data using mutant human lysozymes.
Protein engineering 1999;12(8):663-72.
1999: Takano K; Yamagata Y; Kubota M; Funahashi J; Fujii S; Yutani K
Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six Ser --> Ala mutants.
Biochemistry 1999;38(20):6623-9.
1998: Takano K; Yamagata Y; Yutani K
A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme.
Journal of molecular biology 1998;280(4):749-61.
1998: Yamagata Y; Kubota M; Sumikawa Y; Funahashi J; Takano K; Fujii S; Yutani K
Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Biochemistry 1998;37(26):9355-62.
1997: Takano K; Funahashi J; Yamagata Y; Fujii S; Yutani K
Contribution of water molecules in the interior of a protein to the conformational stability.
Journal of molecular biology 1997;274(1):132-42.
1997: Takano K; Yamagata Y; Fujii S; Yutani K
Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry 1997;36(4):688-98.
1996: Funahashi J; Takano K; Ogasahara K; Yamagata Y; Yutani K
The structure, stability, and folding process of amyloidogenic mutant human lysozyme.
Journal of biochemistry 1996;120(6):1216-23.
1995: Takano K; Ogasahara K; Kaneda H; Yamagata Y; Fujii S; Kanaya E; Kikuchi M; Oobatake M; Yutani K
Contribution of hydrophobic residues to the stability of human lysozyme: calorimetric studies and X-ray structural analysis of the five isoleucine to valine mutants.
Journal of molecular biology 1995;254(1):62-76.

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