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Izumi Takei

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Akira Ogasawara; Yoshifumi Saisho; Siro Simizu; Izumi Takei; Ayumi Ito; Toshihide Kawai; Kazuo Umezawa
Inhibition of NO-induced β-cell death by novel NF-κB inhibitor (-)-DHMEQ via activation of Nrf2-ARE pathway.
Shu Meguro; Midori Ishibashi; Izumi Takei
[The significance of high sensitive C reactive protein as a risk factor for cardiovascular diseases].
Toshihide Kawai; Izumi Takei; Akira Shimada; Takumi Hirata; Kumiko Tanaka; Yoshifumi Saisho; Junichiro Irie; Chihiro Horimai; Hideo Matsumoto; Hiroshi Itoh
Effects of olmesartan medoxomil, an angiotensin II type 1 receptor antagonist, on plasma concentration of B-type natriuretic peptide, in hypertensive patients with type 2 diabetes mellitus: a preliminary, observational, open-label study.

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All Publications

2013: Akira Ogasawara; Yoshifumi Saisho; Siro Simizu; Izumi Takei; Ayumi Ito; Toshihide Kawai; Kazuo Umezawa
Inhibition of NO-induced β-cell death by novel NF-κB inhibitor (-)-DHMEQ via activation of Nrf2-ARE pathway.
Biochemical and biophysical research communications 2013;433(2):181-7.
2012: Shu Meguro; Midori Ishibashi; Izumi Takei
[The significance of high sensitive C reactive protein as a risk factor for cardiovascular diseases].
Rinsho byori. The Japanese journal of clinical pathology 2012;60(4):356-61.
2011: Toshihide Kawai; Izumi Takei; Akira Shimada; Takumi Hirata; Kumiko Tanaka; Yoshifumi Saisho; Junichiro Irie; Chihiro Horimai; Hideo Matsumoto; Hiroshi Itoh
Effects of olmesartan medoxomil, an angiotensin II type 1 receptor antagonist, on plasma concentration of B-type natriuretic peptide, in hypertensive patients with type 2 diabetes mellitus: a preliminary, observational, open-label study.
Clinical drug investigation 2011;31(4):237-45.
2010: Toshihide Kawai; Izumi Takei; Mikiya Tokui; Osamu Funae; Kazunori Miyamoto; Mitsuhisa Tabata; Takumi Hirata; Takao Saruta; Akira Shimada; Hiroshi Itoh
Effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy in patients with type 2 diabetes, in relation to suppression of N(ɛ)-carboxymethyl lysine.
Journal of diabetes and its complications 2010;24(6):424-32.
2008: Yoshifumi Saisho; Hiroshi Hirose; Chihiro Horimai; Kiichi Miyashita; Izumi Takei; Kazuo Umezawa; Hiroshi Itoh
Effects of DHMEQ, a novel nuclear factor-kappab inhibitor, on beta cell dysfunction in INS-1 cells.
Endocrine journal 2008;55(2):433-8.
2005: Koichi Miyaki; Shugo Tohyama; Mitsuru Murata; Haruhito Kikuchi; Izumi Takei; Kiyoaki Watanabe; Kazuyuki Omae
Salt intake affects the relation between hypertension and the T-786C polymorphism in the endothelial nitric oxide synthase gene.
American journal of hypertension 2005;18(12 Pt 1):1556-62.
2005: Koichi Miyaki; Shinya Sutani; Haruhito Kikuchi; Izumi Takei; Mitsuru Murata; Kiyoaki Watanabe; Kazuyuki Omae
Increased risk of obesity resulting from the interaction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men.
Journal of epidemiology / Japan Epidemiological Association 2005;15(6):203-10.
2005: Hideko Tsukamoto; Izumi Takei; Keiko Ishii; Hiroko Fukada; Teruko Ohtake; Haruhito Kikuchi; Nobuyoshi Hirose; Kiyoaki Watanabe
[Analysis of small dense LDL in patients with type 2 diabetic mellitus by the modified Krauss method using an internal standard].
Rinsho byori. The Japanese journal of clinical pathology 2005;53(9):818-24.
2005: Koichi Miyaki; Mitsuru Murata; Haruhito Kikuchi; Izumi Takei; Takeo Nakayama; Kiyoaki Watanabe; Kazuyuki Omae
Assessment of tailor-made prevention of atherosclerosis with folic acid supplementation: randomized, double-blind, placebo-controlled trials in each MTHFR C677T genotype.
Journal of human genetics 2005;50(5):241-8.
2004: Izumi Takei; Tomohiro Kasatani
Future therapy of diabetes mellitus.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2004;58(10):578-81.
2004: Izumi Takei
[Glycoalbumin].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 11():655-8.
2004: Hideko Tsukamoto; Izumi Takei; Keiko Ishii; Kiyoaki Watanabe
Simplified method for the diameter sizing of serum low-density lipoprotein using polyacrylamide gradient gel electrophoresis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2004;42(9):1009-12.
2003: Taro Maruyama; Akira Shimada; Azuma Kanatsuka; Akira Kasuga; Izumi Takei; Junichi Yokoyama; Tetsuro Kobayashi
Multicenter prevention trial of slowly progressive type 1 diabetes with small dose of insulin (the Tokyo study): preliminary report.
Annals of the New York Academy of Sciences 2003;1005():362-9.
2003: Izumi Takei; Kiyoaki Watanabe
[Diabetes mellitus and related nutritional examination].
Rinsho byori. The Japanese journal of clinical pathology 2003;Suppl 127():60-6.
2002: Koichi Miyaki; Izumi Takei; Kiyoaki Watanabe; Hiroshi Nakashima; Kenji Watanabe; Kazuyuki Omae
Novel statistical classification model of type 2 diabetes mellitus patients for tailor-made prevention using data mining algorithm.
Journal of epidemiology / Japan Epidemiological Association 2002;12(3):243-8.
2002: Tetsuro Kobayashi; Taro Maruyama; Akira Shimada; Akira Kasuga; Azuma Kanatsuka; Izumi Takei; Shoichiro Tanaka; Junichi Yokoyama
Insulin intervention to preserve beta cells in slowly progressive insulin-dependent (type 1) diabetes mellitus.
Annals of the New York Academy of Sciences 2002;958():117-30.
2002: Hiroshi Hirose; Toshihide Kawai; Yukihiro Yamamoto; Matsuo Taniyama; Motowo Tomita; Koichi Matsubara; Yasunori Okazaki; Tatsuya Ishii; Yuko Oguma; Izumi Takei; Takao Saruta
Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes.
Metabolism: clinical and experimental 2002;51(3):314-7.
2001: Izumi Takei; K Miyamoto; Osamu Funae; N Ohashi; Shu Meguro; Mikiya Tokui; Takao Saruta
Secretion of GIP in responders to acarbose in obese Type 2(NIDDM) patients.
Journal of diabetes and its complications 2001;15(5):245-9.
2001: Shu Meguro; Izumi Takei; Mitsuru Murata; Hiroshi Hirose; N Takei; Y Mitsuyoshi; Keiko Ishii; Shuji Oguchi; J Shinohara; Eiko Takeshita; Kiyoaki Watanabe; Takao Saruta
Cholesteryl ester transfer protein polymorphism associated with macroangiopathy in Japanese patients with type 2 diabetes.
Atherosclerosis 2001;156(1):151-6.
2001: Osamu Funae; Akira Shimada; Mikiya Tokui; Izumi Takei; Takao Saruta
Balance of GAD65-specific IL-10 production and polyclonal Th1-type response in type 1 diabetes.
Autoimmunity 2001;34(1):45-52.
1999: Toshihide Kawai; Izumi Takei; Yuko Oguma; N Ohashi; Mikiya Tokui; Shuji Oguchi; Fuminori Katsukawa; Hiroshi Hirose; Akira Shimada; Kiyoaki Watanabe; Takao Saruta
Effects of troglitazone on fat distribution in the treatment of male type 2 diabetes.
Metabolism: clinical and experimental 1999;48(9):1102-7.
1998: Y Nitta; Fumi Tashiro; Mikiya Tokui; A Shimada; Izumi Takei; K Tabayashi; J i Miyazaki
Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice.
Human gene therapy 1998;9(12):1701-7.
1998: Izumi Takei; S Takayama; A Yamauchi; S Nakamoto; Y Kitamura; Fuminori Katsukawa; Hajime Yamazaki; Takao Saruta; S Inoue
Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: a preliminary report.
European journal of clinical nutrition 1998;52(2):153-4.
1997: Mikiya Tokui; Izumi Takei; Fumi Tashiro; Akira Shimada; Akira Kasuga; M Ishii; T Ishii; Kiyoshi Takatsu; Takao Saruta; J i Miyazaki
Intramuscular injection of expression plasmid DNA is an effective means of long-term systemic delivery of interleukin-5.
Biochemical and biophysical research communications 1997;233(2):527-31.
1997: A Yamauchi; Izumi Takei; Z Makita; S Nakamoto; N Ohashi; H Kiguchi; T Ishii; T Koike; Takao Saruta
Effects of aminoguanidine on serum advanced glycation endproducts, urinary albilmin excretion, mesangial expansion, and glomerular basement membrane thickening in Otsuka Long-Evans Tokushima fatty rats.
Diabetes research and clinical practice 1997;34(3):127-33.
1996: Tetsuro Kobayashi; Y Oka; H Katagiri; Alberto Falorni; Akira Kasuga; Izumi Takei; Koji Nakanishi; Toshio Murase; K Kosaka; A Lernmark
Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243.
Diabetologia 1996;39(10):1196-200.
1996: Y Ozawa; Akira Kasuga; H Nomaguchi; T Maruyama; T Kasatani; Akira Shimada; Izumi Takei; J Miyazaki; Takao Saruta
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Journal of autoimmunity 1996;9(4):517-24.
1996: Akira Kasuga; Alberto Falorni; T Maruyama; Y Ozawa; C E Grubin; K Matsubara; Izumi Takei; Takao Saruta; A Scheynius; Ake Lernmark
HLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin-dependent diabetes mellitus.
Acta diabetologica 1996;33(2):108-13.
1996: A Yamauchi; Izumi Takei; Akira Kasuga; Y Kitamura; N Ohashi; S Nakano; S Takayama; S Nakamoto; Fuminori Katsukawa; Takao Saruta
Depression of dehydroepiandrosterone in Japanese diabetic men--comparison between non-insulin-dependent diabetes mellitus and impaired glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(1):101-4.
1996: A Yamauchi; Izumi Takei; S Nakamoto; N Ohashi; Y Kitamura; Mikiya Tokui; S Nakano; S Takayama; Akira Kasuga; Fuminori Katsukawa; Takao Saruta
Hyperglycemia decreases dehydroepiandrosterone in Japanese male with impaired glucose tolerance and low insulin response.
Endocrine journal 1996;43(3):285-90.
1996: Akira Kasuga; T Maruyama; Y Ozawa; Izumi Takei; Alberto Falorni; A Lernmark; Takao Saruta
Antibody to the M(r) 65,000 isoform of glutamic acid decarboxylase are detected in non-insulin-dependent diabetes in Japanese.
Journal of autoimmunity 1996;9(1):105-11.
1996: Akira Shimada; T Kasatani; Izumi Takei; T Maruyama; H Nomaguchi; Y Ozawa; M Ishii; Akira Kasuga; Fumi Tashiro; J Miyazaki; K Yamamura; Takao Saruta
Immune response to heat-shock protein correlates with induction of insulitis in I-E alpha d transgenic NOD mice.
Diabetes 1996;45(2):165-9.
1995: Izumi Takei; A Yamauchi; S Nakamoto; H Suzuki; Takao Saruta
Retrospective analysis of hemodialyzed diabetic patients in Japan.
Diabetes research and clinical practice 1995;29(3):173-7.
1995: K Dan; Y Seto; T Fujita; Y Asaba; Izumi Takei; H Fujita; R Kato
Characterization of insulin-dependent diabetes mellitus induced by a new variant (DK-27) of encephalomyocarditis virus in DBA/2 mice.
Experimental animals / Japanese Association for Laboratory Animal Science 1995;44(3):211-8.
1995: Akira Kasuga; Toshio Nakaki; Izumi Takei; S Takayama; Y Ozawa; T Maruyama; J Miyazaki; Takao Saruta
Nitric oxide is important for mouse beta-cell line killing by peritoneal exudate cells obtained from cyclophosphamide treated non-obese diabetic mice.
Endocrine journal 1995;42(2):259-63.
1994: Akira Shimada; Izumi Takei; T Maruyama; Akira Kasuga; T Kasatani; K Watanabe; Y Asaba; T Ishii; T Tadakuma; S Habu
Acceleration of diabetes in young NOD mice with peritoneal macrophages.
Diabetes research and clinical practice 1994;24(2):69-76.
1994: T Maruyama; Akira Shimada; Akira Kasuga; T Kasatani; Y Ozawa; M Ishii; Izumi Takei; Y Suzuki; A Kobayashi; S Takeda
Analysis of MHC class II antigens in Japanese IDDM by a novel HLA-typing method, hybridization protection assay.
Diabetes research and clinical practice 1994;23(2):77-84.
1994: Fumi Tashiro; Akira Kasuga; Akira Shimada; M Ishii; Izumi Takei; T Miyazaki; K Yamamura; J Miyazaki
Resistance to cyclophosphamide-induced diabetes in transgenic NOD mice expressing I-Ak.
Autoimmunity 1994;17(3):181-8.
1994: Alberto Falorni; C E Grubin; Izumi Takei; Akira Shimada; Akira Kasuga; T Maruyama; Y Ozawa; T Kasatani; Takao Saruta; L Li
Radioimmunoassay detects the frequent occurrence of autoantibodies to the Mr 65,000 isoform of glutamic acid decarboxylase in Japanese insulin-dependent diabetes.
Autoimmunity 1994;19(2):113-25.
1993: Akira Kasuga; T Maruyama; Izumi Takei; Akira Shimada; T Kasatani; K Watanabe; Takao Saruta; Toshio Nakaki; S Habu; J Miyazaki
The role of cytotoxic macrophages in non-obese diabetic mice: cytotoxicity against murine mastocytoma and beta-cell lines.
Diabetologia 1993;36(12):1252-7.
1993: Izumi Takei; T Kasatani; K Watanabe; Akira Kasuga; Akira Shimada; T Maruyama; Takao Saruta; H Nomaguchi
Detection of heat shock protein in patients with insulin-dependent diabetes mellitus.
Diabetes research and clinical practice 1993;21(1):25-9.
1993: Akira Kasuga; Izumi Takei; S Tasaka; H Shibata; H Maruyama; Takao Saruta; K Kataoka
A case of aldosterone producing adenoma associated with high PRA after long-term angiotensin converting enzyme inhibitor treatment.
Endocrine journal 1993;40(1):47-52.
1992: Izumi Takei; Y Asaba; T Kasatani; T Maruyama; K Watanabe; T Yanagawa; Takao Saruta; T Ishii
Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection.
Journal of autoimmunity 1992;5(6):665-73.
1992: A Yokoyama; Hiromasa Ishii; T Takagi; S Hori; S Matsushita; S Onishi; Fuminori Katsukawa; Izumi Takei; Shinzo Kato; K Maruyama
Prolonged QT interval in alcoholic autonomic nervous dysfunction.
Alcoholism, clinical and experimental research 1992;16(6):1090-2.
1991: T Maruyama; K Watanabe; Izumi Takei; Akira Kasuga; Akira Shimada; T Yanagawa; T Kasatani; Y Suzuki; K Kataoka
Anti-asialo GM1 antibody suppression of cyclophosphamide-induced diabetes in NOD mice.
Diabetes research (Edinburgh, Scotland) 1991;17(1):37-41.
1991: T Maruyama; K Watanabe; T Yanagawa; T Kasatani; Akira Kasuga; Akira Shimada; Izumi Takei; Y Suzuki; K Kataoka; Takao Saruta
The suppressive effect of anti-asialo GM1 antibody on low-dose streptozotocin-induced diabetes in CD-1 mice.
Diabetes research (Edinburgh, Scotland) 1991;16(4):171-5.
1991: H Wainai; Fuminori Katsukawa; Izumi Takei; H Maruyama; K Kataoka; Takao Saruta
Influence of glycemic control and hypertension on urinary microprotein excretion in non-insulin-dependent diabetes mellitus.
The Journal of diabetic complications 1991;5(2-3):160-1.
1989: T Yanagawa; T Maruyama; Izumi Takei; Y Asaba; T Takahashi; T Ishii; K Kataoka; Takao Saruta; S Minoshima; Nobuyoshi Shimizu
The suppressive effect of cyclophosphamide on low-dose streptozotocin-induced diabetes in mice.
Diabetes research (Edinburgh, Scotland) 1989;12(2):79-83.
1989: T Maruyama; Izumi Takei; Y Asaba; T Yanagawa; T Takahashi; H Itoh; Y Suzuki; K Kataoka; Takao Saruta; T Ishii
Insulin autoantibodies in mouse models of insulin-dependent diabetes.
Diabetes research (Edinburgh, Scotland) 1989;11(2):61-5.
1988: T Maruyama; Izumi Takei; T Yanagawa; T Takahashi; Y Asaba; K Kataoka; T Ishii
Insulin autoantibodies in non-obese diabetic (NOD) mice and streptozotocin-induced diabetic mice.
Diabetes research (Edinburgh, Scotland) 1988;7(2):93-6.