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Tadaomi Takenawa

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Mice
Rats

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Amino Acid Sequence

Anatomy

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Signal Transduction

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Protein Binding

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Co-Publications
Name
39
Suetsugu, Shiro
30
Miki, Hiroshi
19
Fukami, Kiyoko
14
Miki, Hiroaki
12
Yamazaki, Daisuke
10
Yamaguchi, Hideki
10
Ijuin, Takeshi
10
Itoh, Takashi
7
Itoh, Toshiki
7
Yoshida, Nobuaki
6
Tsujita, Kenichi
5
Shimohama, Shun
5
Endo, Takeshi
5
Fissore, Rafael
5
Kataoka, Yuki

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Publications

TOP 3
Matsuda Miho; Tsutsumi Koushirou; Kanematsu Takashi; Fukami Kiyoko; Terada Yoshihiro; Takenawa Tadaomi; Nakayama Keiichi I; Hirata Masato
Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.
Ikonomov Ognian C; Sbrissa Diego; Ijuin Takeshi; Takenawa Tadaomi; Shisheva Assia
Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
Itoh Toshiki; Takenawa Tadaomi
Mechanisms of membrane deformation by lipid-binding domains.

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All Publications

2009: Matsuda Miho; Tsutsumi Koushirou; Kanematsu Takashi; Fukami Kiyoko; Terada Yoshihiro; Takenawa Tadaomi; Nakayama Keiichi I; Hirata Masato
Involvement of phospholipase C-related inactive protein in the mouse reproductive system through the regulation of gonadotropin levels.
Biology of reproduction 2009;81(4):681-9.
2009: Ikonomov Ognian C; Sbrissa Diego; Ijuin Takeshi; Takenawa Tadaomi; Shisheva Assia
Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
The Journal of biological chemistry 2009;284(36):23961-71.
2009: Itoh Toshiki; Takenawa Tadaomi
Mechanisms of membrane deformation by lipid-binding domains.
Progress in lipid research 2009;48(5):298-305.
2009: Fujita Akikazu; Cheng Jinglei; Tauchi-Sato Kumi; Takenawa Tadaomi; Fujimoto Toyoshi
A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9256-61.
2009: Oikawa Tsukasa; Takenawa Tadaomi
PtdIns(3,4)P2 instigates focal adhesions to generate podosomes.
Cell adhesion & migration 2009;3(2):195-7.
2009: Yamazaki D; Kurisu S; Takenawa T
Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates.
Oncogene 2009;28(13):1570-83.
2009: Itoh Toshiki; Hasegawa Junya; Tsujita Kazuya; Kanaho Yasunori; Takenawa Tadaomi
The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration.
Science signaling 2009;2(87):ra52.
2009: Kurisu Shusaku; Takenawa Tadaomi
The WASP and WAVE family proteins.
Genome biology 2009;10(6):226.
2008: Ijuin Takeshi; Yu Y Eugene; Mizutani Kiyohito; Pao Annie; Tateya Sanshiro; Tamori Yoshikazu; Bradley Allan; Takenawa Tadaomi
Increased insulin action in SKIP heterozygous knockout mice.
Molecular and cellular biology 2008;28(17):5184-95.
2008: Oikawa Tsukasa; Itoh Toshiki; Takenawa Tadaomi
Sequential signals toward podosome formation in NIH-src cells.
The Journal of cell biology 2008;182(1):157-69.
2008: Kanzaki Noriyuki; Ogita Hisakazu; Komura Hitomi; Ozaki Misa; Sakamoto Yasuhisa; Majima Takashi; Ijuin Takeshi; Takenawa Tadaomi; Takai Yoshimi
Involvement of the nectin-afadin complex in PDGF-induced cell survival.
Journal of cell science 2008;121(Pt 12):2008-17.
2008: Nakamura Yoshikazu; Ichinohe Manabu; Hirata Masayuki; Matsuura Hirokazu; Fujiwara Takashi; Igarashi Takahiro; Nakahara Masamichi; Yamaguchi Hideki; Yasugi Sadao; Takenawa Tadaomi; Fukami Kiyoko
Phospholipase C-delta1 is an essential molecule downstream of Foxn1, the gene responsible for the nude mutation, in normal hair development.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):841-9.
2008: Akiyama Kiyotaka; Morita Hiroyuki; Suetsugu Shiro; Kuraba Seiko; Numata Yasuharu; Yamamoto Yoshihisa; Inui Kiyoko; Ideura Terukuni; Wakisaka Noriko; Nakano Kiyoko; Oniki Hiroaki; Takenawa Tadaomi; Matsuyama Mutsushi; Yoshimura Ashio
Actin -related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(1):41-50.
2007: Yamashita Masami; Higashi Tomohito; Suetsugu Shiro; Sato Yusuke; Ikeda Tomoyuki; Shirakawa Ryutaro; Kita Toru; Takenawa Tadaomi; Horiuchi Hisanori; Fukai Shuya; Nureki Osamu
Crystal structure of human DAAM1 formin homology 2 domain.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(11):1255-65.
2007: Eto Koji; Nishikii Hidekazu; Ogaeri Takunori; Suetsugu Shiro; Kamiya Akihide; Kobayashi Toshihiro; Yamazaki Daisuke; Oda Atsushi; Takenawa Tadaomi; Nakauchi Hiromitsu
The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.
Blood 2007;110(10):3637-47.
2007: Tokuda Emi; Fujita Naoya; Oh-hara Tomoko; Sato Shigeo; Kurata Atsuo; Katayama Ryohei; Itoh Toshiki; Takenawa Tadaomi; Miyazono Kohei; Tsuruo Takashi
Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
Cancer research 2007;67(20):9666-76.
2007: Takenawa Tadaomi
[Phosphatidylinositol in signal transduction]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2007;52(11):1378-86.
2007: Uezu Akiyoshi; Horiuchi Ayaka; Kanda Kousuke; Kikuchi Naoya; Umeda Kazuaki; Tsujita Kazuya; Suetsugu Shiro; Araki Norie; Yamamoto Hideyuki; Takenawa Tadaomi; Nakanishi Hiroyuki
SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15.
The Journal of biological chemistry 2007;282(36):26481-9.
2007: Yanagida-Asanuma Etsuko; Asanuma Katsuhiko; Kim Kwanghee; Donnelly Mary; Young Choi Hoon; Hyung Chang Jae; Suetsugu Shiro; Tomino Yasuhiko; Takenawa Tadaomi; Faul Christian; Mundel Peter
Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes.
The American journal of pathology 2007;171(2):415-27.
2007: Sbrissa Diego; Ikonomov Ognian C; Fu Zhiyao; Ijuin Takeshi; Gruenberg Jean; Takenawa Tadaomi; Shisheva Assia
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
The Journal of biological chemistry 2007;282(33):23878-91.
2007: Suetsugu Shiro; Banzai Yoshifumi; Kato Masayoshi; Fukami Kiyoko; Kataoka Yuki; Takai Yoshimi; Yoshida Nobuaki; Takenawa Tadaomi
Male-specific sterility caused by the loss of CR16.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(6):721-33.
2007: Yokoyama Takashi; Takano Kazunori; Yoshida Akira; Katada Fumiko; Sun Peng; Takenawa Tadaomi; Andoh Toshiwo; Endo Takeshi
DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation.
The Journal of cell biology 2007;177(5):781-93.
2007: Delawary Mina; Nakazawa Takanobu; Tezuka Tohru; Sawa Mariko; Iino Yuichi; Takenawa Tadaomi; Yamamoto Tadashi
Molecular characterization of a novel RhoGAP, RRC-1 of the nematode Caenorhabditis elegans.
Biochemical and biophysical research communications 2007;357(2):377-82.
2007: Park Sun Joo; Suetsugu Shiro; Sagara Hiroshi; Takenawa Tadaomi
HSP90 cross-links branched actin filaments induced by N-WASP and the Arp2/3 complex.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(5):611-22.
2007: Shimada Atsushi; Niwa Hideaki; Tsujita Kazuya; Suetsugu Shiro; Nitta Koji; Hanawa-Suetsugu Kyoko; Akasaka Ryogo; Nishino Yuri; Toyama Mitsutoshi; Chen Lirong; Liu Zhi-Jie; Wang Bi-Cheng; Yamamoto Masaki; Terada Takaho; Miyazawa Atsuo; Tanaka Akiko; Sugano Sumio; Shirouzu Mikako; Nagayama Kuniaki; Takenawa Tadaomi; Yokoyama Shigeyuki
Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis.
Cell 2007;129(4):761-72.
2007: Nakanishi Osamu; Suetsugu Shiro; Yamazaki Daisuke; Takenawa Tadaomi
Effect of WAVE2 phosphorylation on activation of the Arp2/3 complex.
Journal of biochemistry 2007;141(3):319-25.
2007: Mizokami Akiko; Kanematsu Takashi; Ishibashi Hitoshi; Yamaguchi Taku; Tanida Isei; Takenaka Kei; Nakayama Keiichi I; Fukami Kiyoko; Takenawa Tadaomi; Kominami Eiki; Moss Stephen J; Yamamoto Tsuneyuki; Nabekura Junichi; Hirata Masato
Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1692-701.
2007: Suetsugu Shiro; Takenawa Tadaomi
Stress-associated MAP kinase fills in the map of filamin-mediated neuronal migration.
Developmental cell 2007;12(1):3-4.
2007: Takenawa Tadaomi; Suetsugu Shiro
The WASP-WAVE protein network: connecting the membrane to the cytoskeleton.
Nature reviews. Molecular cell biology 2007;8(1):37-48.
2007: Yamazaki Daisuke; Oikawa Tsukasa; Takenawa Tadaomi
Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion.
Journal of cell science 2007;120(Pt 1):86-100.
2006: Tsuchiya Daiju; Kitamura Yoshihisa; Takata Kazuyuki; Sugisaki Tatsuhiko; Taniguchi Takashi; Uemura Kengo; Miki Hiroaki; Takenawa Tadaomi; Shimohama Shun
Developmental expression of neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE)-related proteins in postnatal rat cerebral cortex and hippocampus.
Neuroscience research 2006;56(4):459-69.
2006: Tsuchiya Daiju; Kitamura Yoshihisa; Takata Kazuyuki; Taniguchi Takashi; Uemura Kengo; Miki Hiroaki; Takenawa Tadaomi; Shimohama Shun
Morphological change by overexpression of D385A dominant negative presenilin 1 in human neuroblastoma SH-SY5Y cells.
Journal of pharmacological sciences 2006;102(3):354-8.
2006: Suetsugu Shiro; Murayama Kazutaka; Sakamoto Ayako; Hanawa-Suetsugu Kyoko; Seto Azusa; Oikawa Tsukasa; Mishima Chiemi; Shirouzu Mikako; Takenawa Tadaomi; Yokoyama Shigeyuki
The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation.
The Journal of biological chemistry 2006;281(46):35347-58.
2006: Akutagawa Atsushi; Fukami Kiyoko; Banno Yoshiko; Takenawa Tadaomi; Kannagi Reiji; Yokoyama Yukihiro; Oda Koji; Nagino Masato; Nimura Yuji; Yoshida Shonen; Tamiya-Koizumi Keiko
Disruption of phospholipase Cdelta4 gene modulates the liver regeneration in cooperation with nuclear protein kinase C.
Journal of biochemistry 2006;140(5):619-25.
2006: Furutani Masahiro; Tsujita Kazuya; Itoh Toshiki; Ijuin Takeshi; Takenawa Tadaomi
Application of phosphoinositide-binding domains for the detection and quantification of specific phosphoinositides.
Analytical biochemistry 2006;355(1):8-18.
2006: Kanematsu Takashi; Yasunaga Atsushi; Mizoguchi Yoshito; Kuratani Akiko; Kittler Josef T; Jovanovic Jasmina N; Takenaka Kei; Nakayama Keiichi I; Fukami Kiyoko; Takenawa Tadaomi; Moss Stephen J; Nabekura Junichi; Hirata Masato
Modulation of GABA(A) receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition.
The Journal of biological chemistry 2006;281(31):22180-9.
2006: Takenawa Tadaomi; Itoh Toshiki
Membrane targeting and remodeling through phosphoinositide-binding domains.
IUBMB life 2006;58(5-6):296-303.
2006: Park SunJoo; Takenawa Tadaomi
[Regulation of actin polymerization by Rho family]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(6 Suppl):511-5.
2006: Suetsugu Shiro; Kurisu Shusaku; Oikawa Tsukasa; Yamazaki Daisuke; Oda Atsushi; Takenawa Tadaomi
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.
The Journal of cell biology 2006;173(4):571-85.
2006: Furutani Masahiro; Itoh Toshiki; Ijuin Takeshi; Tsujita Kazuya; Takenawa Tadaomi
Thin layer chromatography-blotting, a novel method for the detection of phosphoinositides.
Journal of biochemistry 2006;139(4):663-70.
2006: Mitsushima Masaru; Sezaki Takuhito; Akahane Rie; Ueda Kazumitsu; Suetsugu Shiro; Takenawa Tadaomi; Kioka Noriyuki
Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(3):281-92.
2006: Sawa Mariko; Takenawa Tadaomi
Caenorhabditis elegans WASP-interacting protein homologue WIP-1 is involved in morphogenesis through maintenance of WSP-1 protein levels.
Biochemical and biophysical research communications 2006;340(2):709-17.
2006: Tsujita Kazuya; Suetsugu Shiro; Sasaki Nobunari; Furutani Masahiro; Oikawa Tsukasa; Takenawa Tadaomi
Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis.
The Journal of cell biology 2006;172(2):269-79.
2005: Nakamura Yoshikazu; Hamada Yoshio; Fujiwara Takashi; Enomoto Hiroko; Hiroe Takeshi; Tanaka Satoshi; Nose Masato; Nakahara Masamichi; Yoshida Nobuaki; Takenawa Tadaomi; Fukami Kiyoko
Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development.
Molecular and cellular biology 2005;25(24):10979-88.
2005: Mizutani Kiyohito; Koike Daisuke; Suetsugu Shiro; Takenawa Tadaomi
WAVE3 functions as a negative regulator of LDOC1.
Journal of biochemistry 2005;138(5):639-46.
2005: Kawano Yoji; Yoshimura Takeshi; Tsuboi Daisuke; Kawabata Saeko; Kaneko-Kawano Takako; Shirataki Hiromichi; Takenawa Tadaomi; Kaibuchi Kozo
CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation.
Molecular and cellular biology 2005;25(22):9920-35.
2005: Yamazaki Daisuke; Kurisu Shusaku; Takenawa Tadaomi
Regulation of cancer cell motility through actin reorganization.
Cancer science 2005;96(7):379-86.
2005: Yamazaki Daisuke; Fujiwara Takashi; Suetsugu Shiro; Takenawa Tadaomi
A novel function of WAVE in lamellipodia: WAVE1 is required for stabilization of lamellipodial protrusions during cell spreading.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(5):381-92.
2005: Park Sun Joo; Suetsugu Shiro; Takenawa Tadaomi
Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation.
The EMBO journal 2005;24(8):1557-70.
2005: Bierne Hélène; Miki Hiroaki; Innocenti Metello; Scita Giorgio; Gertler Frank B; Takenawa Tadaomi; Cossart Pascale
WASP-related proteins, Abi1 and Ena/VASP are required for Listeria invasion induced by the Met receptor.
Journal of cell science 2005;118(Pt 7):1537-47.
2005: Oda Atsushi; Miki Hiroaki; Wada Ikuo; Yamaguchi Hideki; Yamazaki Daisuke; Suetsugu Shiro; Nakajima Mineba; Nakayama Akira; Okawa Katsuya; Miyazaki Hiroshi; Matsuno Kazuhiko; Ochs Hans D; Machesky Laura M; Fujita Hiroyoshi; Takenawa Tadaomi
WAVE/Scars in platelets.
Blood 2005;105(8):3141-8.
2005: Kato Masayoshi; Takenawa Tadaomi
WICH, a member of WASP-interacting protein family, cross-links actin filaments.
Biochemical and biophysical research communications 2005;328(4):1058-66.
2005: Kurisu Shusaku; Suetsugu Shiro; Yamazaki Daisuke; Yamaguchi Hideki; Takenawa Tadaomi
Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells.
Oncogene 2005;24(8):1309-19.
2005: Yamaguchi Hideki; Lorenz Mike; Kempiak Stephan; Sarmiento Corina; Coniglio Salvatore; Symons Marc; Segall Jeffrey; Eddy Robert; Miki Hiroaki; Takenawa Tadaomi; Condeelis John
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin.
The Journal of cell biology 2005;168(3):441-52.
2005: Takenawa Tadaomi
From N-WASP to WAVE: key molecules for regulation of cortical actin organization.
Novartis Foundation symposium 2005;269():3-10; discussion 10-5, 30-4 passim.
2004: Kawamura Kazuhiro; Takano Kazunori; Suetsugu Shiro; Kurisu Shusaku; Yamazaki Daisuke; Miki Hiroaki; Takenawa Tadaomi; Endo Takeshi
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor.
The Journal of biological chemistry 2004;279(52):54862-71.
2004: Suetsugu Shiro; Tezuka Tohru; Morimura Toshifumi; Hattori Mitsuharu; Mikoshiba Katsuhiko; Yamamoto Tadashi; Takenawa Tadaomi
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1.
The Biochemical journal 2004;384(Pt 1):1-8.
2004: Funato Yosuke; Terabayashi Takeshi; Suenaga Naoko; Seiki Motoharu; Takenawa Tadaomi; Miki Hiroaki
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.
Cancer research 2004;64(15):5237-44.
2004: Verma Suzie; Shewan Annette M; Scott Jeanie A; Helwani Falak M; den Elzen Nicole R; Miki Hiroaki; Takenawa Tadaomi; Yap Alpha S
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts.
The Journal of biological chemistry 2004;279(32):34062-70.
2004: Irino Yasuhiro; Cho Hiroyuki; Nakamura Yoshikazu; Nakahara Masamichi; Furutani Masahiro; Suh Pann-Ghill; Takenawa Tadaomi; Fukami Kiyoko
Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4.
Biochemical and biophysical research communications 2004;320(2):537-43.
2004: Oikawa Tsukasa; Yamaguchi Hideki; Itoh Toshiki; Kato Masayoshi; Ijuin Takeshi; Yamazaki Daisuke; Suetsugu Shiro; Takenawa Tadaomi
PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia.
Nature cell biology 2004;6(5):420-6.
2004: Kurokawa Manabu; Sato Ken-ichi; Smyth Jeremy; Wu Hua; Fukami Kiyoko; Takenawa Tadaomi; Fissore Rafael A
Evidence that activation of Src family kinase is not required for fertilization-associated [Ca2+]i oscillations in mouse eggs.
Reproduction (Cambridge, England) 2004;127(4):441-54.
2004: Tsujita Kazuya; Itoh Toshiki; Ijuin Takeshi; Yamamoto Akitsugu; Shisheva Assia; Laporte Jocelyn; Takenawa Tadaomi
Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction.
The Journal of biological chemistry 2004;279(14):13817-24.
2004: Kouchi Zen; Fukami Kiyoko; Shikano Tomohide; Oda Shoji; Nakamura Yoshikazu; Takenawa Tadaomi; Miyazaki Shunichi
Recombinant phospholipase Czeta has high Ca2+ sensitivity and induces Ca2+ oscillations in mouse eggs.
The Journal of biological chemistry 2004;279(11):10408-12.
2004: Wu Xiaoyang; Suetsugu Shiro; Cooper Lee Ann; Takenawa Tadaomi; Guan Jun-Lin
Focal adhesion kinase regulation of N-WASP subcellular localization and function.
The Journal of biological chemistry 2004;279(10):9565-76.
2004: Mizutani Kiyohito; Suetsugu Shiro; Takenawa Tadaomi
FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation.
Biochemical and biophysical research communications 2004;313(3):468-74.
2004: Itoh T; Takenawa T
Regulation of endocytosis by phosphatidylinositol 4,5-bisphosphate and ENTH proteins.
Current topics in microbiology and immunology 2004;282():31-47.
2003: Suetsugu Shiro; Yamazaki Daisuke; Kurisu Shusaku; Takenawa Tadaomi
Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration.
Developmental cell 2003;5(4):595-609.
2003: Takenaka Kei; Fukami Kiyoko; Otsuki Makiko; Nakamura Yoshikazu; Kataoka Yuki; Wada Mika; Tsuji Kohichiro; Nishikawa Shin-Ichi; Yoshida Nobuaki; Takenawa Tadaomi
Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling.
Molecular and cellular biology 2003;23(20):7329-38.
2003: Suetsugu Shiro; Takenawa Tadaomi
Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90.
The Journal of biological chemistry 2003;278(43):42515-23.
2003: Miki Hiroaki; Takenawa Tadaomi
Regulation of actin dynamics by WASP family proteins.
Journal of biochemistry 2003;134(3):309-13.
2003: Kitamura Yoshihisa; Tsuchiya Daiju; Takata Kazuyuki; Shibagaki Keiichi; Taniguchi Takashi; Smith Mark A; Perry George; Miki Hiroaki; Takenawa Tadaomi; Shimohama Shun
Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease.
Neuroscience letters 2003;346(3):149-52.
2003: Yamazaki Daisuke; Suetsugu Shiro; Miki Hiroaki; Kataoka Yuki; Nishikawa Shin-Ichi; Fujiwara Takashi; Yoshida Nobuaki; Takenawa Tadaomi
WAVE2 is required for directed cell migration and cardiovascular development.
Nature 2003;424(6947):452-6.
2003: Kitamura Yoshihisa; Shibagaki Keiichi; Takata Kazuyuki; Tsuchiya Daiju; Taniguchi Takashi; Gebicke-Haerter Peter J; Miki Hiroaki; Takenawa Tadaomi; Shimohama Shun
Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) and Rac1 in the phagocytosis of amyloid-beta(1-42) in rat microglia.
Journal of pharmacological sciences 2003;92(2):115-23.
2003: Nakamura Yoshikazu; Fukami Kiyoko; Yu Haiyan; Takenaka Kei; Kataoka Yuki; Shirakata Yuji; Nishikawa Shin-Ichi; Hashimoto Koji; Yoshida Nobuaki; Takenawa Tadaomi
Phospholipase Cdelta1 is required for skin stem cell lineage commitment.
The EMBO journal 2003;22(12):2981-91.
2003: Nakagawa Hiroyuki; Miki Hiroaki; Nozumi Motohiro; Takenawa Tadaomi; Miyamoto Shigeaki; Wehland Jürgen; Small J Victor
IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena.
Journal of cell science 2003;116(Pt 12):2577-83.
2003: Matuoka Koozi; Chen Kuang Yu; Takenawa Tadaomi
A positive role of phosphatidylinositol 3-kinase in aging phenotype expression in cultured human diploid fibroblasts.
Archives of gerontology and geriatrics 2003;36(3):203-19.
2003: Fukami Kiyoko; Yoshida Manabu; Inoue Takafumi; Kurokawa Manabu; Fissore Rafael A; Yoshida Nobuaki; Mikoshiba Katsuhiko; Takenawa Tadaomi
Phospholipase Cdelta4 is required for Ca2+ mobilization essential for acrosome reaction in sperm.
The Journal of cell biology 2003;161(1):79-88.
2003: Sawa Mariko; Suetsugu Shiro; Sugimoto Asako; Miki Hiroaki; Yamamoto Masayuki; Takenawa Tadaomi
Essential role of the C. elegans Arp2/3 complex in cell migration during ventral enclosure.
Journal of cell science 2003;116(Pt 8):1505-18.
2003: Klein Christoph; Nguyen Deanna; Liu Ching-Hui; Mizoguchi Atsushi; Bhan Atul K; Miki Hiroaki; Takenawa Tadaomi; Rosen Fred S; Alt Fred W; Mulligan Richard C; Snapper Scott B
Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.
Blood 2003;101(6):2159-66.
2003: Ijuin Takeshi; Takenawa Tadaomi
SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.
Molecular and cellular biology 2003;23(4):1209-20.
2003: Otsuki Makiko; Itoh Toshiki; Takenawa Tadaomi
Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor.
The Journal of biological chemistry 2003;278(8):6461-9.
2003: Sun Peng; Yamamoto Hironobu; Suetsugu Shiro; Miki Hiroaki; Takenawa Tadaomi; Endo Takeshi
Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation.
The Journal of biological chemistry 2003;278(6):4063-71.
2003: Tobe Kazuyuki; Asai Shohji; Matuoka Koozi; Yamamoto Tadashi; Chida Kazuhiro; Kaburagi Yasushi; Akanuma Yasuo; Kuroki Toshio; Takenawa Tadaomi; Kimura Satoshi; Nagai Ryozo; Kadowaki Takashi
Cytoskeletal reorganization induced by insulin: involvement of Grb2/Ash, Ras and phosphatidylinositol 3-kinase signalling.
Genes to cells : devoted to molecular & cellular mechanisms 2003;8(1):29-40.
2003: Nozumi Motohiro; Nakagawa Hiroyuki; Miki Hiroaki; Takenawa Tadaomi; Miyamoto Shigeaki
Differential localization of WAVE isoforms in filopodia and lamellipodia of the neuronal growth cone.
Journal of cell science 2003;116(Pt 2):239-46.
2003: Abe Tomoyuki; Kato Masayoshi; Miki Hiroaki; Takenawa Tadaomi; Endo Takeshi
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth.
Journal of cell science 2003;116(Pt 1):155-68.
2003: Suetsugu Shiro; Takenawa Tadaomi
Regulation of cortical actin networks in cell migration.
International review of cytology 2003;229():245-86.
2003: Fukami Kiyoko; Inoue Takafumi; Kurokawa Manabu; Fissore Rafael A; Nakao Kazuki; Nagano Kohji; Nakamura Yoshikazu; Takenaka Kei; Yoshida Nobuaki; Mikoshiba Katuhiko; Takenawa Tadaomi
Phospholipase Cdelta4: from genome structure to physiological function.
Advances in enzyme regulation 2003;43():87-106.
2002: Suetsugu Shiro; Hattori Mitsuharu; Miki Hiroaki; Tezuka Tohru; Yamamoto Tadashi; Mikoshiba Katsuhiko; Takenawa Tadaomi
Sustained activation of N-WASP through phosphorylation is essential for neurite extension.
Developmental cell 2002;3(5):645-58.
2002: Sayama Koji; Yamasaki Kenshi; Hanakawa Yasushi; Shirakata Yuji; Tokumaru Sho; Ijuin Takeshi; Takenawa Tadaomi; Hashimoto Koji
Phosphatidylinositol 3-kinase is a key regulator of early phase differentiation in keratinocytes.
The Journal of biological chemistry 2002;277(43):40390-6.
2002: Yamaguchi Hideki; Miki Hiroaki; Takenawa Tadaomi
Two verprolin homology domains increase the Arp2/3 complex-mediated actin polymerization activities of N-WASP and WAVE1 C-terminal regions.
Biochemical and biophysical research communications 2002;297(2):214-9.
2002: Itoh Toshiki; Takenawa Tadaomi
Phosphoinositide-binding domains: Functional units for temporal and spatial regulation of intracellular signalling.
Cellular signalling 2002;14(9):733-43.
2002: Fujiwara Ikuko; Suetsugu Shiro; Uemura Sotaro; Takenawa Tadaomi; Ishiwata Shin'ichi
Visualization and force measurement of branching by Arp2/3 complex and N-WASP in actin filament.
Biochemical and biophysical research communications 2002;293(5):1550-5.
2002: Yamaguchi Hideki; Miki Hiroaki; Takenawa Tadaomi
Neural Wiskott-Aldrich syndrome protein is involved in hepatocyte growth factor-induced migration, invasion, and tubulogenesis of epithelial cells.
Cancer research 2002;62(9):2503-9.
2002: Miki Hiroaki; Takenawa Tadaomi
WAVE2 serves a functional partner of IRSp53 by regulating its interaction with Rac.
Biochemical and biophysical research communications 2002;293(1):93-9.
2002: Suzuki Toshihiko; Mimuro Hitomi; Suetsugu Shiro; Miki Hiroaki; Takenawa Tadaomi; Sasakawa Chihiro
Neural Wiskott-Aldrich syndrome protein (N-WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin-based spreading.
Cellular microbiology 2002;4(4):223-33.
2002: Suetsugu Shiro; Miki Hiroaki; Takenawa Tadaomi
Spatial and temporal regulation of actin polymerization for cytoskeleton formation through Arp2/3 complex and WASP/WAVE proteins.
Cell motility and the cytoskeleton 2002;51(3):113-22.
2002: Mizutani Kiyohito; Miki Hiroaki; He Hong; Maruta Hiroshi; Takenawa Tadaomi
Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts.
Cancer research 2002;62(3):669-74.
2002: Kato Masayoshi; Miki Hiroaki; Kurita Souichi; Endo Takeshi; Nakagawa Hiroyuki; Miyamoto Shigeaki; Takenawa Tadaomi
WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation.
Biochemical and biophysical research communications 2002;291(1):41-7.
2002: Vetterkind Susanne; Miki Hiroaki; Takenawa Tadaomi; Klawitz Ingrid; Scheidtmann Karl-Heinz; Preuss Ute
The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation.
The Journal of biological chemistry 2002;277(1):87-95.
2001: Matuoka K; Chen K Y; Takenawa T
Rapid reversion of aging phenotypes by nicotinamide through possible modulation of histone acetylation.
Cellular and molecular life sciences : CMLS 2001;58(14):2108-16.
2001: Suetsugu S; Miki H; Yamaguchi H; Obinata T; Takenawa T
Enhancement of branching efficiency by the actin filament-binding activity of N-WASP/WAVE2.
Journal of cell science 2001;114(Pt 24):4533-42.
2001: Takenawa T; Itoh T
Phosphoinositides, key molecules for regulation of actin cytoskeletal organization and membrane traffic from the plasma membrane.
Biochimica et biophysica acta 2001;1533(3):190-206.
2001: Suetsugu S; Miki H; Takenawa T
Identification of another actin-related protein (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin polymerization induced by the Arp2/3 complex activating (VCA) domain of N-WASP.
The Journal of biological chemistry 2001;276(35):33175-80.
2001: Minagawa T; Ijuin T; Mochizuki Y; Takenawa T
Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase.
The Journal of biological chemistry 2001;276(25):22011-5.
2001: Fukami K; Nakao K; Inoue T; Kataoka Y; Kurokawa M; Fissore R A; Nakamura K; Katsuki M; Mikoshiba K; Yoshida N; Takenawa T
Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction.
Science (New York, N.Y.) 2001;292(5518):920-3.
2001: Takenawa T; Miki H
WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement.
Journal of cell science 2001;114(Pt 10):1801-9.
2001: Wu H; Smyth J; Luzzi V; Fukami K; Takenawa T; Black S L; Allbritton N L; Fissore R A
Sperm factor induces intracellular free calcium oscillations by stimulating the phosphoinositide pathway.
Biology of reproduction 2001;64(5):1338-49.
2001: Suetsugu S; Miki H; Yamaguchi H; Takenawa T
Requirement of the basic region of N-WASP/WAVE2 for actin-based motility.
Biochemical and biophysical research communications 2001;282(3):739-44.
2001: Itoh T; Koshiba S; Kigawa T; Kikuchi A; Yokoyama S; Takenawa T
Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis.
Science (New York, N.Y.) 2001;291(5506):1047-51.
2001: Fukuoka M; Suetsugu S; Miki H; Fukami K; Endo T; Takenawa T
A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42.
The Journal of cell biology 2001;152(3):471-82.
2001: Park S J; Itoh T; Takenawa T
Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli.
The Journal of biological chemistry 2001;276(7):4781-7.
2000: Miki H; Yamaguchi H; Suetsugu S; Takenawa T
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.
Nature 2000;408(6813):732-5.
2000: Suzuki A; Kadota N; Hara T; Nakagami Y; Izumi T; Takenawa T; Sabe H; Endo T
Meltrin alpha cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src.
Oncogene 2000;19(51):5842-50.
2000: Yamaguchi H; Miki H; Suetsugu S; Ma L; Kirschner M W; Takenawa T
Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12631-6.
2000: Mimuro H; Suzuki T; Suetsugu S; Miki H; Takenawa T; Sasakawa C
Profilin is required for sustaining efficient intra- and intercellular spreading of Shigella flexneri.
The Journal of biological chemistry 2000;275(37):28893-901.
2000: Miki H; Takenawa T
[WASP-family, a critical signal transducer linking various signals to rapid actin-polymerization]
Seikagaku. The Journal of Japanese Biochemical Society 2000;72(7):550-4.
2000: Suzuki T; Mimuro H; Miki H; Takenawa T; Sasaki T; Nakanishi H; Takai Y; Sasakawa C
Rho family GTPase Cdc42 is essential for the actin-based motility of Shigella in mammalian cells.
The Journal of experimental medicine 2000;191(11):1905-20.
2000: Sasaki N; Miki H; Takenawa T
Arp2/3 complex-independent actin regulatory function of WAVE.
Biochemical and biophysical research communications 2000;272(2):386-90.
2000: Itoh T; Ishihara H; Shibasaki Y; Oka Y; Takenawa T
Autophosphorylation of type I phosphatidylinositol phosphate kinase regulates its lipid kinase activity.
The Journal of biological chemistry 2000;275(25):19389-94.
2000: Banzai Y; Miki H; Yamaguchi H; Takenawa T
Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells.
The Journal of biological chemistry 2000;275(16):11987-92.
2000: Ijuin T; Mochizuki Y; Fukami K; Funaki M; Asano T; Takenawa T
Identification and characterization of a novel inositol polyphosphate 5-phosphatase.
The Journal of biological chemistry 2000;275(15):10870-5.
2000: Fukami K; Takenaka K; Nagano K; Takenawa T
Growth factor-induced promoter activation of murine phospholipase C delta4 gene.
European journal of biochemistry / FEBS 2000;267(1):28-36.
1999: Mochizuki Y; Takenawa T
Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles.
The Journal of biological chemistry 1999;274(51):36790-5.
1999: Otsuki M; Fukami K; Kohno T; Yokota J; Takenawa T
Identification and characterization of a new phospholipase C-like protein, PLC-L(2).
Biochemical and biophysical research communications 1999;266(1):97-103.
1999: Hiroyama M; Takenawa T
Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis.
The Journal of biological chemistry 1999;274(41):29172-80.
1999: Miki H; Fukuda M; Nishida E; Takenawa T
Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling.
The Journal of biological chemistry 1999;274(39):27605-9.
1999: Kato M; Miki H; Imai K; Nonoyama S; Suzuki T; Sasakawa C; Takenawa T
Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42.
The Journal of biological chemistry 1999;274(38):27225-30.
1999: Suetsugu S; Miki H; Takenawa T
Distinct roles of profilin in cell morphological changes: microspikes, membrane ruffles, stress fibers, and cytokinesis.
FEBS letters 1999;457(3):470-4.
1999: Imai K; Nonoyama S; Miki H; Morio T; Fukami K; Zhu Q; Aruffo A; Ochs H D; Yata J; Takenawa T
The pleckstrin homology domain of the Wiskott-Aldrich syndrome protein is involved in the organization of actin cytoskeleton.
Clinical immunology (Orlando, Fla.) 1999;92(2):128-37.
1999: Asano T; Mochizuki Y; Matsumoto K; Takenawa T; Endo T
Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts.
Biochemical and biophysical research communications 1999;261(1):188-95.
1999: Itoh T; Takenawa T
[Phosphatidylinositol kinase: functional roles for PI4-kinase and PIP kinase in signal transduction]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(8 Suppl):949-60.
1999: Suetsugu S; Miki H; Takenawa T
Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.
Biochemical and biophysical research communications 1999;260(1):296-302.
1999: Takenawa T; Itoh T; Fukami K
Regulation of phosphatidylinositol 4,5-bisphosphate levels and its roles in cytoskeletal re-organization and malignant transformation.
Chemistry and physics of lipids 1999;98(1-2):13-22.
1999: Nagano K; Fukami K; Minagawa T; Watanabe Y; Ozaki C; Takenawa T
A novel phospholipase C delta4 (PLCdelta4) splice variant as a negative regulator of PLC.
The Journal of biological chemistry 1999;274(5):2872-9.
1998: Miki H; Suetsugu S; Takenawa T
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac.
The EMBO journal 1998;17(23):6932-41.
1998: Hiroyama M; Takenawa T
Purification and characterization of a lysophosphatidic acid-specific phosphatase.
The Biochemical journal 1998;336 ( Pt 2)():483-9.
1998: Suetsugu S; Miki H; Takenawa T
The essential role of profilin in the assembly of actin for microspike formation.
The EMBO journal 1998;17(22):6516-26.
1998: Yu H; Fukami K; Itoh T; Takenawa T
Phosphorylation of phospholipase Cgamma1 on tyrosine residue 783 by platelet-derived growth factor regulates reorganization of the cytoskeleton.
Experimental cell research 1998;243(1):113-22.
1998: Itoh T; Ijuin T; Takenawa T
A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase IIgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signals.
The Journal of biological chemistry 1998;273(32):20292-9.
1998: Suzuki T; Miki H; Takenawa T; Sasakawa C
Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri.
The EMBO journal 1998;17(10):2767-76.
1998: Shimohama S; Sumida Y; Fujimoto S; Matsuoka Y; Taniguchi T; Takenawa T; Kimura J
Differential expression of rat brain phospholipase C isozymes in development and aging.
Biochemical and biophysical research communications 1998;243(1):210-6.
1998: Miki H; Takenawa T
Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization.
Biochemical and biophysical research communications 1998;243(1):73-8.
1998: Yu H; Fukami K; Watanabe Y; Ozaki C; Takenawa T
Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1.
European journal of biochemistry / FEBS 1998;251(1-2):281-7.
1998: Miki H; Sasaki T; Takai Y; Takenawa T
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP.
Nature 1998;391(6662):93-6.
1998: Takenawa T; Miki H; Matuoka K
Signaling through Grb2/Ash-control of the Ras pathway and cytoskeleton.
Current topics in microbiology and immunology 1998;228():325-42.
1997: Fukuoka M; Miki H; Takenawa T
Identification of N-WASP homologs in human and rat brain.
Gene 1997;196(1-2):43-8.
1997: Sakisaka T; Itoh T; Miura K; Takenawa T
Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments.
Molecular and cellular biology 1997;17(7):3841-9.
1997: Miki H; Nonoyama S; Zhu Q; Aruffo A; Ochs H D; Takenawa T
Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(2):195-202.
1996: Itoh T; Miura K; Miki H; Takenawa T
Beta-tubulin binds Src homology 2 domains through a region different from the tyrosine-phosphorylated protein-recognizing site.
The Journal of biological chemistry 1996;271(44):27931-5.
1996: Miki H; Miura K; Takenawa T
N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.
The EMBO journal 1996;15(19):5326-35.
1996: Miura K; Miki H; Shimazaki K; Kawai N; Takenawa T
Interaction of Ash/Grb-2 via its SH3 domains with neuron-specific p150 and p65.
The Biochemical journal 1996;316 ( Pt 2)():639-45.
1996: Fukami K; Sawada N; Endo T; Takenawa T
Identification of a phosphatidylinositol 4,5-bisphosphate-binding site in chicken skeletal muscle alpha-actinin.
The Journal of biological chemistry 1996;271(5):2646-50.
1996: Liu N; Fukami K; Yu H; Takenawa T
A new phospholipase C delta 4 is induced at S-phase of the cell cycle and appears in the nucleus.
The Journal of biological chemistry 1996;271(1):355-60.
1996: Takenawa T; Miura K; Miki H; Watanabe K
Signal transductions of SH2/SH3: Ash/Grb-2 downstream signaling.
Advances in pharmacology (San Diego, Calif.) 1996;36():139-53.
1995: Hirano N; Shibasaki F; Sakai R; Tanaka T; Nishida J; Yazaki Y; Takenawa T; Hirai H
Molecular cloning of the human glucose-regulated protein ERp57/GRP58, a thiol-dependent reductase. Identification of its secretory form and inducible expression by the oncogenic transformation.
European journal of biochemistry / FEBS 1995;234(1):336-42.
1995: Nakamura F; Kato M; Kameyama K; Nukada T; Haga T; Kato H; Takenawa T; Kikkawa U
Characterization of Gq family G proteins GL1 alpha (G14 alpha), GL2 alpha (G11 alpha), and Gq alpha expressed in the baculovirus-insect cell system.
The Journal of biological chemistry 1995;270(11):6246-53.
1994: Hirano N; Shibasaki F; Kato H; Sakai R; Tanaka T; Nishida J; Yazaki Y; Takenawa T; Hirai H
Molecular cloning and characterization of a cDNA for bovine phospholipase C-alpha: proposal of redesignation of phospholipase C-alpha.
Biochemical and biophysical research communications 1994;204(1):375-82.
1994: Shibasaki F; Fukami K; Fukui Y; Takenawa T
Phosphatidylinositol 3-kinase binds to alpha-actinin through the p85 subunit.
The Biochemical journal 1994;302 ( Pt 2)():551-7.
1994: Miki H; Miura K; Matuoka K; Nakata T; Hirokawa N; Orita S; Kaibuchi K; Takai Y; Takenawa T
Association of Ash/Grb-2 with dynamin through the Src homology 3 domain.
The Journal of biological chemistry 1994;269(8):5489-92.
1994: Fukami K; Endo T; Imamura M; Takenawa T
alpha-Actinin and vinculin are PIP2-binding proteins involved in signaling by tyrosine kinase.
The Journal of biological chemistry 1994;269(2):1518-22.
1994: Gotoh N; Tojo A; Muroya K; Hashimoto Y; Hattori S; Nakamura S; Takenawa T; Yazaki Y; Shibuya M
Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):167-71.
1992: Shiroki K; Yamakawa A; Shibata M; Takenawa T; Sugano S; Nomoto A
Adenovirus E1A proteins stimulate inositol phospholipid metabolism in PC12 cells.
Journal of virology 1992;66(10):6093-8.
1992: Tanaka T; Shibasaki F; Ishikawa M; Hirano N; Sakai R; Nishida J; Takenawa T; Hirai H
Molecular cloning of bovine actin-like protein, actin2.
Biochemical and biophysical research communications 1992;187(2):1022-8.
1988: Huang M; Chida K; Kamata N; Nose K; Kato M; Homma Y; Takenawa T; Kuroki T
Enhancement of inositol phospholipid metabolism and activation of protein kinase C in ras-transformed rat fibroblasts.
The Journal of biological chemistry 1988;263(34):17975-80.
1988: Uno I; Fukami K; Kato H; Takenawa T; Ishikawa T
Essential role for phosphatidylinositol 4,5-bisphosphate in yeast cell proliferation.
Nature 1988;333(6169):188-90.

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