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Akira Takeshita

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
151
Shimokawa, Hiroaki
147
Egashira, Kensuke
81
Hirooka, Yoshitaka
64
Tsutsui, Hiroyuki
33
Ichiki, Toshihiro
32
Mohri, Masahiro
29
Kuga, T
26
Usui, Makoto
25
Tagawa, Tatsuya
23
Kitamoto, Shiro
23
Fukumoto, Yoshihiro
20
Ide, Tomomi
19
Hayashidani, Shunji
18
Ito, Koji
18
Kishi, Takuya

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Publications

TOP 3
Tsuchihashi-Makaya Miyuki; Hamaguchi Sanae; Kinugawa Shintaro; Yokota Takashi; Goto Daisuke; Yokoshiki Hisashi; Kato Norihiro; Takeshita Akira; Tsutsui Hiroyuki;
Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD).
Tsuchihashi-Makaya Miyuki; Kato Norihiro; Chishaki Akiko; Takeshita Akira; Tsutsui Hiroyuki
Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure.
Kishi Takuya; Hirooka Yoshitaka; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Atorvastatin reduces oxidative stress in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.

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All Publications

2009: Tsuchihashi-Makaya Miyuki; Hamaguchi Sanae; Kinugawa Shintaro; Yokota Takashi; Goto Daisuke; Yokoshiki Hisashi; Kato Norihiro; Takeshita Akira; Tsutsui Hiroyuki;
Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD).
Circulation journal : official journal of the Japanese Circulation Society 2009;73(10):1893-900.
2009: Tsuchihashi-Makaya Miyuki; Kato Norihiro; Chishaki Akiko; Takeshita Akira; Tsutsui Hiroyuki
Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(2):280-7.
2008: Kishi Takuya; Hirooka Yoshitaka; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Atorvastatin reduces oxidative stress in the rostral ventrolateral medulla of stroke-prone spontaneously hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2008;30(1):3-11.
2007: Fukumoto Yoshihiro; Kishi Takuya; Tsutsui Hiroyuki; Yamada Akira; Okamatsu Shuichi; Takeshita Akira
Elevated serum C-reactive protein levels as a predictive indicator for subsequent renal impairment in patients with acute heart failure.
The Tohoku journal of experimental medicine 2007;213(4):361-8.
2007: Fukumoto Yoshihiro; Mohri Masahiro; Inokuchi Kosuke; Ito Akira; Hirakawa Yoji; Masumoto Akihiro; Hirooka Yoshitaka; Takeshita Akira; Shimokawa Hiroaki
Anti-ischemic effects of fasudil, a specific Rho-kinase inhibitor, in patients with stable effort angina.
Journal of cardiovascular pharmacology 2007;49(3):117-21.
2006: Fukuyama Kae; Ichiki Toshihiro; Imayama Ikuyo; Ohtsubo Hideki; Ono Hiroki; Hashiguchi Yasuko; Takeshita Akira; Sunagawa Kenji
Thyroid hormone inhibits vascular remodeling through suppression of cAMP response element binding protein activity.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(9):2049-55.
2006: Fukumoto Yoshihiro; Ito Akira; Uwatoku Toyokazu; Matoba Tetsuya; Kishi Takuya; Tanaka Haruki; Takeshita Akira; Sunagawa Kenji; Shimokawa Hiroaki
Extracorporeal cardiac shock wave therapy ameliorates myocardial ischemia in patients with severe coronary artery disease.
Coronary artery disease 2006;17(1):63-70.
2006: Ono Hiroki; Ichiki Toshihiro; Ohtsubo Hideki; Fukuyama Kae; Imayama Ikuyo; Iino Naoko; Masuda Satoko; Hashiguchi Yasuko; Takeshita Akira; Sunagawa Kenji
CAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2006;29(1):39-47.
2005: Fukuyama Kae; Ichiki Toshihiro; Ono Hiroki; Tokunou Tomotake; Iino Naoko; Masuda Satoko; Ohtsubo Hideki; Takeshita Akira
cAMP-response element-binding protein mediates prostaglandin F2alpha-induced hypertrophy of vascular smooth muscle cells.
Biochemical and biophysical research communications 2005;338(2):910-8.
2005: Matsusaka Hidenori; Ikeuchi Masaki; Matsushima Shouji; Ide Tomomi; Kubota Toru; Feldman Arthur M; Takeshita Akira; Sunagawa Kenji; Tsutsui Hiroyuki
Selective disruption of MMP-2 gene exacerbates myocardial inflammation and dysfunction in mice with cytokine-induced cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2005;289(5):H1858-64.
2005: Shimokawa Hiroaki; Takeshita Akira
Rho-kinase is an important therapeutic target in cardiovascular medicine.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1767-75.
2005: Kawano Shunichi; Kubota Toru; Monden Yoshiya; Kawamura Natsumi; Tsutsui Hiroyuki; Takeshita Akira; Sunagawa Kenji
Blockade of NF-kappaB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II.
Cardiovascular research 2005;67(4):689-98.
2005: Ito Koji; Hirooka Yoshitaka; Hori Nobuaki; Kimura Yoshikuni; Sagara Yoji; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Inhibition of rho-kinase in the nucleus tractus solitarius enhances glutamate sensitivity in rats.
Hypertension 2005;46(2):360-5.
2005: Ikeuchi Masaki; Matsusaka Hidenori; Kang Dongchon; Matsushima Shouji; Ide Tomomi; Kubota Toru; Fujiwara Toshiyuki; Hamasaki Naotaka; Takeshita Akira; Sunagawa Kenji; Tsutsui Hiroyuki
Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction.
Circulation 2005;112(5):683-90.
2005: Eto Yasuhiro; Shimokawa Hiroaki; Fukumoto Yoshihiro; Matsumoto Yasuharu; Morishige Kunio; Kunihiro Ikuko; Kandabashi Tadashi; Takeshita Akira
Combination therapy with cerivastatin and nifedipine improves endothelial dysfunction after balloon injury in porcine coronary arteries.
Journal of cardiovascular pharmacology 2005;46(1):1-6.
2005: Kawamura Natsumi; Kubota Toru; Kawano Shunichi; Monden Yoshiya; Feldman Arthur M; Tsutsui Hiroyuki; Takeshita Akira; Sunagawa Kenji
Blockade of NF-kappaB improves cardiac function and survival without affecting inflammation in TNF-alpha-induced cardiomyopathy.
Cardiovascular research 2005;66(3):520-9.
2005: Kishi Takuya; Hirooka Yoshitaka; Masumoto Akihiro; Ito Koji; Kimura Yoshikuni; Inokuchi Kosuke; Tagawa Tatsuya; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure.
Circulation 2005;111(21):2741-7.
2005: Morikawa Keiko; Matoba Tetsuya; Kubota Hiroshi; Hatanaka Makoto; Fujiki Takako; Takahashi Shosuke; Takeshita Akira; Shimokawa Hiroaki
Influence of diabetes mellitus, hypercholesterolemia, and their combination on EDHF-mediated responses in mice.
Journal of cardiovascular pharmacology 2005;45(5):485-90.
2005: Zhao Yingjun; Fukumoto Yoshihiro; Mohri Masahiro; Shimokawa Hiroaki; Takeshita Akira
Impact of sex and age on coronary basal tone.
Internal medicine (Tokyo, Japan) 2005;44(4):354-5.
2005: Fujiki Takako; Shimokawa Hiroaki; Morikawa Keiko; Kubota Hiroshi; Hatanaka Makoto; Talukder M A Hassan; Matoba Tetsuya; Takeshita Akira; Sunagawa Kenji
Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin-converting enzyme inhibitor on endothelium-derived hyperpolarizing factor-mediated responses in mice.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):766-71.
2005: Ito Koji; Hirooka Yoshitaka; Kimura Yoshikuni; Shimokawa Hiroaki; Takeshita Akira
Effects of hydroxyfasudil administered to the nucleus tractus solitarii on blood pressure and heart rate in spontaneously hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2005;27(2-3):269-77.
2005: Kimura Yoshikuni; Hirooka Yoshitaka; Sagara Yoji; Ito Koji; Kishi Takuya; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Overexpression of inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress.
Circulation research 2005;96(2):252-60.
2005: Hiroki Junko; Shimokawa Hiroaki; Mukai Yasushi; Ichiki Toshihiro; Takeshita Akira
Divergent effects of estrogen and nicotine on Rho-kinase expression in human coronary vascular smooth muscle cells.
Biochemical and biophysical research communications 2005;326(1):154-9.
2004: Ikeuchi Masaki; Tsutsui Hiroyuki; Shiomi Tetsuya; Matsusaka Hidenori; Matsushima Shouji; Wen Jing; Kubota Toru; Takeshita Akira
Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction.
Cardiovascular research 2004;64(3):526-35.
2004: Zhao Qingwei; Egashira Kensuke; Hiasa Ken-ichi; Ishibashi Minako; Inoue Shujiro; Ohtani Kisho; Tan Chunyan; Shibuya Masabumi; Takeshita Akira; Sunagawa Kenji
Essential role of vascular endothelial growth factor and Flt-1 signals in neointimal formation after periadventitial injury.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2284-9.
2004: Nishida Takahiro; Shimokawa Hiroaki; Oi Keiji; Tatewaki Hideki; Uwatoku Toyokazu; Abe Kohtaro; Matsumoto Yasuharu; Kajihara Noriyoshi; Eto Masataka; Matsuda Takehisa; Yasui Hisataka; Takeshita Akira; Sunagawa Kenji
Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo.
Circulation 2004;110(19):3055-61.
2004: Talukder M A Hassan; Fujiki Takako; Morikawa Keiko; Motoishi Minako; Matsuo Yoko; Hatanaka Makoto; Tsutsui Masato; Takeshita Akira; Shimokawa Hiroaki
Endothelial nitric oxide synthase-independent effects of an ACE inhibitor on coronary flow response to bradykinin in aged mice.
Journal of cardiovascular pharmacology 2004;44(5):557-63.
2004: Ishibashi Minako; Egashira Kensuke; Zhao Qingwei; Hiasa Ken-ichi; Ohtani Kisho; Ihara Yoshiko; Charo Israel F; Kura Shinobu; Tsuzuki Teruhisa; Takeshita Akira; Sunagawa Kenji
Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):e174-8.
2004: Hirooka Yoshitaka; Shimokawa Hiroaki; Takeshita Akira
Rho-kinase, a potential therapeutic target for the treatment of hypertension.
Drug news & perspectives 2004;17(8):523-7.
2004: Hiroki Junko; Fukumoto Yoshihiro; Shimokawa Hiroaki; Hirooka Yoshitaka; Takeshita Akira
[Inhibition of Rho-kinase by fasudil preventing anginal attacks associated with spastic angina: a case report]
Journal of cardiology 2004;44(4):161-4.
2004: Tsuchihashi Miyuki; Tsutsui Hiroyuki; Tada Hideo; Shihara Miwako; Takeshita Akira; Kono Suminori;
Volume-outcome relation for hospitals performing angioplasty for acute myocardial infarction: results from the Nationwide Japanese Registry.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(10):887-91.
2004: Talukder M A Hassan; Fujiki Takako; Morikawa Keiko; Motoishi Minako; Kubota Hiroshi; Morishita Tsuyoshi; Tsutsui Masato; Takeshita Akira; Shimokawa Hiroaki
Up-regulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide synthase-deficient mice.
Journal of cardiovascular pharmacology 2004;44(4):437-45.
2004: Ichiki Toshihiro; Tokunou Tomotake; Fukuyama Kae; Iino Naoko; Masuda Satoko; Takeshita Akira
15-Deoxy-Delta12,14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth muscle cells.
Biochemical and biophysical research communications 2004;323(2):402-8.
2004: Ito Koji; Hirooka Yoshitaka; Sagara Yoji; Kimura Yoshikuni; Kaibuchi Kozo; Shimokawa Hiroaki; Takeshita Akira; Sunagawa Kenji
Inhibition of Rho-kinase in the brainstem augments baroreflex control of heart rate in rats.
Hypertension 2004;44(4):478-83.
2004: Zhao Qingwei; Ishibashi Minako; Hiasa Ken-ichi; Tan Chunyan; Takeshita Akira; Egashira Kensuke
Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.
Hypertension 2004;44(3):264-70.
2004: Ono Hiroki; Ichiki Toshihiro; Fukuyama Kae; Iino Naoko; Masuda Satoko; Egashira Kensuke; Takeshita Akira
cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1634-9.
2004: Hiroki Junko; Shimokawa Hiroaki; Higashi Midoriko; Morikawa Keiko; Kandabashi Tadashi; Kawamura Natsumi; Kubota Toru; Ichiki Toshihiro; Amano Mutsuki; Kaibuchi Kozo; Takeshita Akira
Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells.
Journal of molecular and cellular cardiology 2004;37(2):537-46.
2004: Ohtani K; Usui M; Nakano K; Kohjimoto Y; Kitajima S; Hirouchi Y; Li X-H; Kitamoto S; Takeshita A; Egashira K
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys.
Gene therapy 2004;11(16):1273-82.
2004: Chishaki Akiko Suyama; Li Fang-Jie; Takeshita Akira; Chishaki Hiroaki
Different features of ventricular arrhythmias and the RR-interval dynamics in atrial fibrillation related to the patient's clinical characteristics: an analysis using RR-interval plotting.
Journal of electrocardiology 2004;37(3):207-17.
2004: Oi Keiji; Shimokawa Hiroaki; Hirakawa Yoji; Tashiro Hideki; Nakaike Ryuichi; Kozai Toshiyuki; Ohzono Keizaburo; Yamamoto Kunihiko; Koyanagi Samon; Okamatsu Shuichi; Tajimi Tsukasa; Kikuchi Yutaka; Takeshita Akira
Postprandial increase in plasma concentrations of remnant-like particles: an independent risk factor for restenosis after percutaneous coronary intervention.
Journal of cardiovascular pharmacology 2004;44(1):66-73.
2004: Hiasa Ken-ichi; Ishibashi Minako; Ohtani Kisho; Inoue Shujiro; Zhao Qingwei; Kitamoto Shiro; Sata Masataka; Ichiki Toshihiro; Takeshita Akira; Egashira Kensuke
Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovascularization.
Circulation 2004;109(20):2454-61.
2004: Kishi Takuya; Hirooka Yoshitaka; Kimura Yoshikuni; Ito Koji; Shimokawa Hiroaki; Takeshita Akira
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Circulation 2004;109(19):2357-62.
2004: Hattori Tsuyoshi; Shimokawa Hiroaki; Higashi Midoriko; Hiroki Junko; Mukai Yasushi; Tsutsui Hiroyuki; Kaibuchi Kozo; Takeshita Akira
Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice.
Circulation 2004;109(18):2234-9.
2004: Hiasa Ken-ichi; Egashira Kensuke; Kitamoto Shiro; Ishibashi Minako; Inoue Shujiro; Ni Weihua; Zhao Qingwei; Nagata Shin; Katoh Makoto; Sata Masataka; Takeshita Akira
Bone marrow mononuclear cell therapy limits myocardial infarct size through vascular endothelial growth factor.
Basic research in cardiology 2004;99(3):165-72.
2004: Ishibashi Minako; Hiasa Ken-ichi; Zhao Qingwei; Inoue Shujiro; Ohtani Kisho; Kitamoto Shiro; Tsuchihashi Miyuki; Sugaya Takeshi; Charo Israel F; Kura Shinobu; Tsuzuki Teruhisa; Ishibashi Tatsuro; Takeshita Akira; Egashira Kensuke
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.
Circulation research 2004;94(9):1203-10.
2004: Oi Keiji; Shimokawa Hiroaki; Hiroki Junko; Uwatoku Toyokazu; Abe Kohtaro; Matsumoto Yasuharu; Nakajima Yasuhiro; Nakajima Katsuyuki; Takeichi Sanae; Takeshita Akira
Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(5):918-22.
2004: Washio Masakazu; Tokunaga Shoji; Yoshimasu Kouichi; Kodama Hiroko; Liu Ying; Sasazuki Shizuka; Tanaka Keitaro; Kono Suminori; Mohri Masahiro; Takeshita Akira; Arakawa Kikuo; Ideishi Munehito; Nii Takanobu; Shirai Kazuyuki; Arai Hidekazu; Doi Yoshitaka; Kawano Tomoki; Nakagaki Osamu; Takada Kazuyuki; Hiyamuta Koji; Koyanagi Samon
Role of prehypertension in the development of coronary atherosclerosis in Japan.
Journal of epidemiology / Japan Epidemiological Association 2004;14(2):57-62.
2004: Ni Weihua; Kitamoto Shiro; Ishibashi Minako; Usui Makoto; Inoue Shujiro; Hiasa Ken-ichi; Zhao Qingwei; Nishida Ken-ichi; Takeshita Akira; Egashira Kensuke
Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):534-9.
2004: Shiomi Tetsuya; Tsutsui Hiroyuki; Matsusaka Hidenori; Murakami Kimiyo; Hayashidani Shunji; Ikeuchi Masaki; Wen Jing; Kubota Toru; Utsumi Hideo; Takeshita Akira
Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice.
Circulation 2004;109(4):544-9.
2004: Ito Koji; Hirooka Yoshitaka; Kishi Takuya; Kimura Yoshikuni; Kaibuchi Kozo; Shimokawa Hiroaki; Takeshita Akira
Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
Hypertension 2004;43(2):156-62.
2004: Kataoka Chu; Egashira Kensuke; Ishibashi Minako; Inoue Shujiro; Ni Weihua; Hiasa Ken-ichi; Kitamoto Shiro; Usui Makoto; Takeshita Akira
Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis.
American journal of physiology. Heart and circulatory physiology 2004;286(2):H768-74.
2004: Ohtani K; Egashira K; Usui M; Ishibashi M; Hiasa K-I; Zhao Q; Aoki M; Kaneda Y; Morishita R; Takeshita A
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits.
Gene therapy 2004;11(2):126-32.
2004: Hattori Tsuyoshi; Shimokawa Hiroaki; Higashi Midoriko; Hiroki Junko; Mukai Yasushi; Kaibuchi Kozo; Takeshita Akira
Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice.
Circulation research 2004;94(1):46-52.
2004: Matsumoto Yasuharu; Uwatoku Toyokazu; Oi Keiji; Abe Kohtaro; Hattori Tsuyoshi; Morishige Kunio; Eto Yasuhiro; Fukumoto Yoshihiro; Nakamura Kei-ichiro; Shibata Yosaburo; Matsuda Takehisa; Takeshita Akira; Shimokawa Hiroaki
Long-term inhibition of Rho-kinase suppresses neointimal formation after stent implantation in porcine coronary arteries: involvement of multiple mechanisms.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):181-6.
2003: Hirooka Yoshitaka; Shigematsu Hideaki; Kishi Takuya; Kimura Yoshikuni; Ueta Yoichi; Takeshita Akira
Reduced nitric oxide synthase in the brainstem contributes to enhanced sympathetic drive in rats with heart failure.
Journal of cardiovascular pharmacology 2003;42 Suppl 1():S111-5.
2003: Hirooka Yoshitaka; Eshima Kenichi; Setoguchi Soko; Kishi Takuya; Egashira Kensuke; Takeshita Akira
Vitamin C improves attenuated angiotensin II-induced endothelium-dependent vasodilation in human forearm vessels.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(12):953-9.
2003: Morikawa Keiko; Shimokawa Hiroaki; Matoba Tetsuya; Kubota Hiroshi; Akaike Takaaki; Talukder M A Hassan; Hatanaka Makoto; Fujiki Takako; Maeda Hiroshi; Takahashi Shosuke; Takeshita Akira
Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization.
The Journal of clinical investigation 2003;112(12):1871-9.
2003: Sakai N; Sendo T; Itoh Y; Hirakawa Y; Takeshita A; Oishi R
Delayed adverse reactions to iodinated radiographic contrast media after coronary angiography: a search for possible risk factors.
Journal of clinical pharmacy and therapeutics 2003;28(6):505-12.
2003: Kandabashi Tadashi; Shimokawa Hiroaki; Miyata Kenji; Kunihiro Ikuko; Eto Yasuhiro; Morishige Kunio; Matsumoto Yasuharu; Obara Kazuo; Nakayama Koichi; Takahashi Shosuke; Takeshita Akira
Evidence for protein kinase C-mediated activation of Rho-kinase in a porcine model of coronary artery spasm.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(12):2209-14.
2003: Inokuchi Kosuke; Hirooka Yoshitaka; Shimokawa Hiroaki; Sakai Koji; Kishi Takuya; Ito Koji; Kimura Yoshikuni; Takeshita Akira
Role of endothelium-derived hyperpolarizing factor in human forearm circulation.
Hypertension 2003;42(5):919-24.
2003: Inoue Takahiro; Fukumoto Yoshihiro; Mohri Masahiro; Inokuchi Kosuke; Hirakawa Yoji; Takeshita Akira
Images in cardiovascular medicine. Wandering ST-segment elevation.
Circulation 2003;108(14):e102-3.
2003: Hayashidani Shunji; Tsutsui Hiroyuki; Shiomi Tetsuya; Ikeuchi Masaki; Matsusaka Hidenori; Suematsu Nobuhiro; Wen Jing; Egashira Kensuke; Takeshita Akira
Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2003;108(17):2134-40.
2003: Higashi Midoriko; Shimokawa Hiroaki; Hattori Tsuyoshi; Hiroki Junko; Mukai Yasushi; Morikawa Keiko; Ichiki Toshihiro; Takahashi Shosuke; Takeshita Akira
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system.
Circulation research 2003;93(8):767-75.
2003: Ito Koji; Ichiki Toshihiro; Ohi Keiji; Egashira Kensuke; Ohta Mituhiko; Taguchi Kenichi; Takeshita Akira
Pulmonary capillary hemangiomatosis with severe pulmonary hypertension.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(9):793-5.
2003: Tokunou Tomotake; Shibata Rei; Kai Hisashi; Ichiki Toshihiro; Morisaki Takashi; Fukuyama Kae; Ono Hiroki; Iino Naoko; Masuda Satoko; Shimokawa Hiroaki; Egashira Kensuke; Imaizumi Tsutomu; Takeshita Akira
Apoptosis induced by inhibition of cyclic AMP response element-binding protein in vascular smooth muscle cells.
Circulation 2003;108(10):1246-52.
2003: Hayashidani Shunji; Tsutsui Hiroyuki; Ikeuchi Masaki; Shiomi Tetsuya; Matsusaka Hidenori; Kubota Toru; Imanaka-Yoshida Kyoko; Itoh Takeshi; Takeshita Akira
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1229-35.
2003: Ichiki Toshihiro; Tokunou Tomotake; Fukuyama Kae; Iino Naoko; Masuda Satoko; Takeshita Akira
Cyclic AMP response element-binding protein mediates reactive oxygen species-induced c-fos expression.
Hypertension 2003;42(2):177-83.
2003: Mohri Masahiro; Ichiki Toshihiro; Kuga Takeshi; Takeshita Akira
Evidence for anti-ischemic effect of dual-chamber pacing in patients with the obstructive form of hypertrophic cardiomyopathy.
Japanese heart journal 2003;44(4):587-92.
2003: Fukumoto Yoshihiro; Tsutsui Hiroyuki; Tsuchihashi Miyuki; Masumoto Akihiro; Takeshita Akira;
The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study.
Journal of the American College of Cardiology 2003;42(2):211-6.
2003: Shiomi Tetsuya; Tsutsui Hiroyuki; Ikeuchi Masaki; Matsusaka Hidenori; Hayashidani Shunji; Suematsu Nobuhiro; Wen Jing; Kubota Toru; Takeshita Akira
Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction.
Journal of the American College of Cardiology 2003;42(1):165-72.
2003: Mukai Yasushi; Shimokawa Hiroaki; Matoba Tetsuya; Hiroki Junko; Kunihiro Ikuko; Fujiki Takako; Takeshita Akira
Acute vasodilator effects of HMG-CoA reductase inhibitors: involvement of PI3-kinase/Akt pathway and Kv channels.
Journal of cardiovascular pharmacology 2003;42(1):118-24.
2003: Matoba Tetsuya; Shimokawa Hiroaki; Morikawa Keiko; Kubota Hiroshi; Kunihiro Ikuko; Urakami-Harasawa Lemmy; Mukai Yasushi; Hirakawa Yoji; Akaike Takaaki; Takeshita Akira
Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1224-30.
2003: Ito Koji; Hirooka Yoshitaka; Sakai Koji; Kishi Takuya; Kaibuchi Kozo; Shimokawa Hiroaki; Takeshita Akira
Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension.
Circulation research 2003;92(12):1337-43.
2003: Kubota Toru; Takeshita Akira
[Treatment of heart failure based on large-scale clinical trials: renin-angiotensin system antagonists and beta-blockers]
Nippon rinsho. Japanese journal of clinical medicine 2003;61(5):801-6.
2003: Tsuchihashi Miyuki; Tsutsui Hiroyuki; Shihara Miwako; Tada Hideo; Kono Suminori; Takeshita Akira;
Comparison of outcomes for patients undergoing balloon angioplasty vs coronary stenting for acute myocardial infarction.
Circulation journal : official journal of the Japanese Circulation Society 2003;67(5):369-74.
2003: Tada Hideo; Tsutsui Hiroyuki; Takeshita Akira
[Long-term prognosis of coronary artery bypass surgery in Japan]
Nippon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():583-7.
2003: Tsutsui Hiroyuki; Takeshita Akira
[PCI: results of nationwide survey in Japan]
Nippon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():489-94.
2003: Hirooka Yoshitaka; Sakai Koji; Kishi Takuya; Ito Koji; Shimokawa Hiroaki; Takeshita Akira
Enhanced depressor response to endothelial nitric oxide synthase gene transfer into the nucleus tractus solitarii of spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(4):325-31.
2003: Uwatoku Toyokazu; Shimokawa Hiroaki; Abe Kohtaro; Matsumoto Yasuharu; Hattori Tsuyoshi; Oi Keiji; Matsuda Takehisa; Kataoka Kazunori; Takeshita Akira
Application of nanoparticle technology for the prevention of restenosis after balloon injury in rats.
Circulation research 2003;92(7):e62-9.
2003: Kitamoto Shiro; Egashira Kensuke; Takeshita Akira
Stress and vascular responses: anti-inflammatory therapeutic strategy against atherosclerosis and restenosis after coronary intervention.
Journal of pharmacological sciences 2003;91(3):192-6.
2003: Suematsu Nobuhiro; Tsutsui Hiroyuki; Wen Jing; Kang Dongchon; Ikeuchi Masaki; Ide Tomomi; Hayashidani Shunji; Shiomi Tetsuya; Kubota Toru; Hamasaki Naotaka; Takeshita Akira
Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes.
Circulation 2003;107(10):1418-23.
2003: Fukuyama Kae; Ichiki Toshihiro; Takeda Kotaro; Tokunou Tomotake; Iino Naoko; Masuda Satoko; Ishibashi Minako; Egashira Kensuke; Shimokawa Hiroaki; Hirano Katsuya; Kanaide Hideo; Takeshita Akira
Downregulation of vascular angiotensin II type 1 receptor by thyroid hormone.
Hypertension 2003;41(3):598-603.
2003: Shimokawa Hiroaki; Eto Yasuhiro; Miyata Kenji; Morishige Kunio; Kandabashi Tadashi; Matsushima Kouji; Takeshita Akira
Propagermanium suppresses macrophage-mediated formation of coronary arteriosclerotic lesions in pigs in vivo.
Journal of cardiovascular pharmacology 2003;41(3):372-80.
2003: Tanaka Eriko; Shimokawa Hiroaki; Kamiuneten Hitoshi; Eto Yasuhiro; Matsumoto Yasuharu; Morishige Kunio; Koike George; Yoshinaga Masaru; Egashira Kensuke; Tokunaga Osamu; Shiomi Masashi; Takeshita Akira
Disparity of MCP-1 mRNA and protein expressions between the carotid artery and the aorta in WHHL rabbits: one aspect involved in the regional difference in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(2):244-50.
2003: Kishi Takuya; Hirooka Yoshitaka; Kimura Yoshikuni; Sakai Koji; Ito Koji; Shimokawa Hiroaki; Takeshita Akira
Overexpression of eNOS in RVLM improves impaired baroreflex control of heart rate in SHRSP. Rostral ventrolateral medulla. Stroke-prone spontaneously hypertensive rats.
Hypertension 2003;41(2):255-60.
2003: Kishi Takuya; Hirooka Yoshitaka; Mukai Yasushi; Shimokawa Hiroaki; Takeshita Akira
Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats.
Journal of hypertension 2003;21(2):379-86.
2003: Morishige Kunio; Shimokawa Hiroaki; Matsumoto Yasuharu; Eto Yasuhiro; Uwatoku Toyokazu; Abe Kohtaro; Sueishi Katsuo; Takeshita Akira
Overexpression of matrix metalloproteinase-9 promotes intravascular thrombus formation in porcine coronary arteries in vivo.
Cardiovascular research 2003;57(2):572-85.
2003: Eto Yasuhiro; Shimokawa Hiroaki; Tanaka Eriko; Morishige Kunio; Fuchigami Masahiro; Ishiwata Yoshiro; Matsushima Kouji; Takeshita Akira
Long-term treatment with propagermanium suppresses atherosclerosis in WHHL rabbits.
Journal of cardiovascular pharmacology 2003;41(2):171-7.
2003: Machida Yoji; Kubota Toru; Kawamura Natsumi; Funakoshi Hajime; Ide Tomomi; Utsumi Hideo; Li Yun You; Feldman Arthur M; Tsutsui Hiroyuki; Shimokawa Hiroaki; Takeshita Akira
Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium.
American journal of physiology. Heart and circulatory physiology 2003;284(2):H449-55.
2003: Hirooka Yoshitaka; Kishi Takuya; Sakai Koji; Shimokawa Hiroaki; Takeshita Akira
Effect of overproduction of nitric oxide in the brain stem on the cardiovascular response in conscious rats.
Journal of cardiovascular pharmacology 2003;41 Suppl 1():S119-26.
2003: Mohri Masahiro; Shimokawa Hiroaki; Hirakawa Yoji; Masumoto Akihiro; Takeshita Akira
Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with coronary microvascular spasm.
Journal of the American College of Cardiology 2003;41(1):15-9.
2002: Shiomi Tetsuya; Tsutsui Hiroyuki; Hayashidani Shunji; Suematsu Nobuhiro; Ikeuchi Masaki; Wen Jing; Ishibashi Minako; Kubota Toru; Egashira Kensuke; Takeshita Akira
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2002;106(24):3126-32.
2002: Tagawa Tatsuya; Hirooka Yoshitaka; Shimokawa Hiroaki; Hironaga Kiyoshi; Sakai Koji; Oyama Jun-ichi; Takeshita Akira
Long-term treatment with eicosapentaenoic acid improves exercise-induced vasodilation in patients with coronary artery disease.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(6):823-9.
2002: Inoue Shujiro; Egashira Kensuke; Ni Weihua; Kitamoto Shiro; Usui Makoto; Otani Kisho; Ishibashi Minako; Hiasa Ken-ichi; Nishida Ken-ichi; Takeshita Akira
Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice.
Circulation 2002;106(21):2700-6.
2002: Ishibashi Minako; Egashira Kensuke; Hiasa Ken-ichi; Inoue Shujiro; Ni Weihua; Zhao Qingwei; Usui Makoto; Kitamoto Shiro; Ichiki Toshihiro; Takeshita Akira
Antiinflammatory and antiarteriosclerotic effects of pioglitazone.
Hypertension 2002;40(5):687-93.
2002: Shihara Miwako; Tsutsui Hiroyuki; Tsuchihashi Miyuki; Tada Hideo; Kono Suminori; Takeshita Akira;
In-hospital and one-year outcomes for patients undergoing percutaneous coronary intervention for acute myocardial infarction.
The American journal of cardiology 2002;90(9):932-6.
2002: Ikeda Yasuhiro; Yonemitsu Yoshikazu; Kataoka Chu; Kitamoto Shiro; Yamaoka Terutoshi; Nishida Ken-Ichi; Takeshita Akira; Egashira Kensuke; Sueishi Katsuo
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats.
American journal of physiology. Heart and circulatory physiology 2002;283(5):H2021-8.
2002: Usui Makoto; Egashira Kensuke; Ohtani Kisho; Kataoka Chu; Ishibashi Minako; Hiasa Ken-ichi; Katoh Makoto; Zhao Qingwei; Kitamoto Shiro; Takeshita Akira
Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1838-40.
2002: Abe Kohtaro; Shimokawa Hiroaki; Kubota Toru; Nawa Yukifumi; Takeshita Akira
Myocarditis associated with visceral larva migrans due to Toxocara canis.
Internal medicine (Tokyo, Japan) 2002;41(9):706-8.
2002: Mukai Yasushi; Shimokawa Hiroaki; Higashi Midoriko; Morikawa Keiko; Matoba Tetsuya; Hiroki Junko; Kunihiro Ikuko; Talukder Hassan M A; Takeshita Akira
Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(9):1445-50.
2002: Fukumoto Yoshihiro; Urabe Yoshitoshi; Kubo Toshihiko; Kaku Tohru; Egashira Kensuke; Shimokawa Hiroaki; Takeshita Akira
Augmented vasodilator response to L-arginine after coronary angioplasty may attenuate restenosis.
Heart and vessels 2002;16(5):171-4.
2002: Nakamura Ryo; Egashira Kensuke; Machida Youji; Hayashidani Shunji; Takeya Motohiro; Utsumi Hideo; Tsutsui Hiroyuki; Takeshita Akira
Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation.
Circulation 2002;106(3):362-7.
2002: Mori Emiko; Komori Kimihiro; Yamaoka Terutoshi; Tanii Mitsugu; Kataoka Chu; Takeshita Akira; Usui Makoto; Egashira Kensuke; Sugimachi Keizo
Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits.
Circulation 2002;105(24):2905-10.
2002: Egashira Kensuke; Zhao Qingwei; Kataoka Chu; Ohtani Kishou; Usui Makoto; Charo Israel F; Nishida Ken-Ichi; Inoue Shujiro; Katoh Makoto; Ichiki Toshihiro; Takeshita Akira
Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.
Circulation research 2002;90(11):1167-72.
2002: Funakoshi Hajime; Kubota Toru; Machida Yoji; Kawamura Natsumi; Feldman Arthur M; Tsutsui Hiroyuki; Shimokawa Hiroaki; Takeshita Akira
Involvement of inducible nitric oxide synthase in cardiac dysfunction with tumor necrosis factor-alpha.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H2159-66.
2002: Funakoshi Hajime; Kubota Toru; Kawamura Natsumi; Machida Yoji; Feldman Arthur M; Tsutsui Hiroyuki; Shimokawa Hiroaki; Takeshita Akira
Disruption of inducible nitric oxide synthase improves beta-adrenergic inotropic responsiveness but not the survival of mice with cytokine-induced cardiomyopathy.
Circulation research 2002;90(9):959-65.
2002: Funakoshi Yuko; Ichiki Toshihiro; Takeda Kotaro; Tokuno Tomotake; Iino Naoko; Takeshita Akira
Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells.
The Journal of biological chemistry 2002;277(21):18710-7.
2002: Masumoto Akihiro; Mohri Masahiro; Shimokawa Hiroaki; Urakami Lemmy; Usui Makoto; Takeshita Akira
Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina.
Circulation 2002;105(13):1545-7.
2002: Mohri Masahiro; Ichiki Toshihiro; Hirooka Yoshitaka; Takeshita Akira
Endogenous nitric oxide prevents myocardial ischemia in patients with hypertension and left ventricular hypertrophy.
American heart journal 2002;143(4):684-9.
2002: Matsumoto Yasuharu; Shimokawa Hiroaki; Morishige Kunio; Eto Yasuhiro; Takeshita Akira
Reduction in neointimal formation with a stent coated with multiple layers of releasable heparin in porcine coronary arteries.
Journal of cardiovascular pharmacology 2002;39(4):513-22.
2002: Kubo-Inoue Mayuko; Egashira Kensuke; Usui Makoto; Takemoto Masao; Ohtani Kisho; Katoh Makoto; Shimokawa Hiroaki; Takeshita Akira
Long-term inhibition of nitric oxide synthesis increases arterial thrombogenecity in rat carotid artery.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1478-84.
2002: Ide Tomomi; Tsutsui Hiroyuki; Ohashi Noriko; Hayashidani Shunji; Suematsu Nobuhiro; Tsuchihashi Miyuki; Tamai Hiroshi; Takeshita Akira
Greater oxidative stress in healthy young men compared with premenopausal women.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):438-42.
2002: Zhao Qingwei; Egashira Kensuke; Inoue Shujiro; Usui Makoto; Kitamoto Shiro; Ni Weihua; Ishibashi Minako; Hiasa Ki Ken-ichi; Ichiki Toshihiro; Shibuya Masabumi; Takeshita Akira
Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis.
Circulation 2002;105(9):1110-5.
2002: Sun Hongtao; Mohri Masahiro; Shimokawa Hiroaki; Usui Makoto; Urakami Lemmy; Takeshita Akira
Coronary microvascular spasm causes myocardial ischemia in patients with vasospastic angina.
Journal of the American College of Cardiology 2002;39(5):847-51.
2002: Setoguchi Soko; Hirooka Yoshitaka; Eshima Kenichi; Shimokawa Hiroaki; Takeshita Akira
Tetrahydrobiopterin improves impaired endothelium-dependent forearm vasodilation in patients with heart failure.
Journal of cardiovascular pharmacology 2002;39(3):363-8.
2002: Kawamura Nobutoshi; Tsutsui Hiroyuki; Fukuyama Kae; Hayashidani Shunji; Koike George; Egashira Kensuke; Abe Yasunobu; Yamamoto Hidetaka; Tsuneyoshi Masazumi; Takeshita Akira
Severe pulmonary hypertension in a patient with systemic lupus erythematosus and minimal lupus activity.
Internal medicine (Tokyo, Japan) 2002;41(2):109-12.
2002: Hayashidani Shunji; Tsutsui Hiroyuki; Shiomi Tetsuya; Suematsu Nobuhiro; Kinugawa Shintaro; Ide Tomomi; Wen Jing; Takeshita Akira
Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2002;105(7):868-73.
2002: Kishi Takuya; Hirooka Yoshitaka; Ito Koji; Sakai Koji; Shimokawa Hiroaki; Takeshita Akira
Cardiovascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats.
Hypertension 2002;39(2):264-8.
2002: Kataoka Chu; Egashira Kensuke; Inoue Shujiro; Takemoto Masao; Ni Weihua; Koyanagi Masamichi; Kitamoto Shiro; Usui Makoto; Kaibuchi Kozo; Shimokawa Hiroaki; Takeshita Akira
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Hypertension 2002;39(2):245-50.
2002: Kandabashi Tadashi; Shimokawa Hiroaki; Mukai Yasushi; Matoba Tetsuya; Kunihiro Ikuko; Morikawa Keiko; Ito Masaaki; Takahashi Shosuke; Kaibuchi Kozo; Takeshita Akira
Involvement of rho-kinase in agonists-induced contractions of arteriosclerotic human arteries.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):243-8.
2002: Shigematsu Hideaki; Tsutsui Hiroyuki; Shihara Miwako; Tsuchihashi Miyuki; Koike George; Yamamoto Shimako; Kono Suminori; Takeshita Akira;
Coronary revascularization in Japan. Part 4: coronary artery bypass surgery during 1997.
Circulation journal : official journal of the Japanese Circulation Society 2002;66(1):20-9.
2002: Shihara Miwako; Tsutsui Hiroyuki; Tsuchihashi Miyuki; Shigematsu Hideaki; Yamamoto Shimako; Koike George; Kono Suminori; Takeshita Akira;
Coronary revascularization in Japan. Part 3: percutaneous coronary intervention during 1997.
Circulation journal : official journal of the Japanese Circulation Society 2002;66(1):10-9.
2002: Matoba Tetsuya; Shimokawa Hiroaki; Kubota Hiroshi; Morikawa Keiko; Fujiki Takako; Kunihiro Ikuko; Mukai Yasushi; Hirakawa Yoji; Takeshita Akira
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries.
Biochemical and biophysical research communications 2002;290(3):909-13.
2002: Satoh Shinji; Suematsu Nobuhiro; Ueda Yasuko; Tsutsui Hiroyuki; Egashira Kensuke; Takeshita Akira; Makino Naoki
Post-beta-receptor impairment in the regulation of myofibrillar Ca2+ sensitivity in tachypacing-induced canine failing heart.
Journal of cardiovascular pharmacology 2002;39(1):88-97.
2002: Yoshimasu Kouichi; Washio Masakazu; Tokunaga Shoji; Tanaka Keitaro; Liu Ying; Kodama Hiroko; Arai Hidekazu; Koyanagi Samon; Hiyamuta Koji; Doi Yoshitaka; Kawano Tomoki; Nakagaki Osamu; Takada Kazuyuki; Sasazuki Shizuka; Nii Takanobu; Shirai Kazuyuki; Ideishi Munehito; Arakawa Kikuo; Mohri Masahiro; Takeshita Akira
Relation between type A behavior pattern and the extent of coronary atherosclerosis in Japanese women.
International journal of behavioral medicine 2002;9(2):77-93.
2001: Morishige K; Shimokawa H; Eto Y; Hoshijima M; Kaibuchi K; Takeshita A
In vivo gene transfer of dominant-negative rho-kinase induces regression of coronary arteriosclerosis in pigs.
Annals of the New York Academy of Sciences 2001;947():407-11.
2001: Tsuchihashi M; Tsutsui H; Shihara M; Shigematsu H; Yamamoto S; Koike G; Kono S; Takeshita A;
Coronary revascularization in Japan. Part 2: comparison of facilities between 1997 and 1999.
Japanese circulation journal 2001;65(12):1011-6.
2001: Shihara M; Tsutsui H; Tsuchihashi M; Shigematsu H; Yamamoto S; Koike G; Kono S; Takeshita A;
Coronary revascularization in Japan. Part 1: survey of facilities during 1997.
Japanese circulation journal 2001;65(12):1005-10.
2001: Masumoto A; Hirooka Y; Shimokawa H; Hironaga K; Setoguchi S; Takeshita A
Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans.
Hypertension 2001;38(6):1307-10.
2001: Masumoto A; Mohri M; Takeshita A
Three-year follow-up of the Japanese patients with microvascular angina attributable to coronary microvascular spasm.
International journal of cardiology 2001;81(2-3):151-6.
2001: Ichiki T; Takeda K; Tokunou T; Iino N; Egashira K; Shimokawa H; Hirano K; Kanaide H; Takeshita A
Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(12):1896-901.
2001: Tsutsui H; Ide T; Shiomi T; Kang D; Hayashidani S; Suematsu N; Wen J; Utsumi H; Hamasaki N; Takeshita A
8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts.
Circulation 2001;104(24):2883-5.
2001: Masumoto A; Hirooka Y; Hironaga K; Eshima K; Setoguchi S; Egashira K; Takeshita A
Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin).
The American journal of cardiology 2001;88(11):1291-4.
2001: Nakamura R; Egashira K; Arimura K; Machida Y; Ide T; Tsutsui H; Shimokawa H; Takeshita A
Increased inactivation of nitric oxide is involved in impaired coronary flow reserve in heart failure.
American journal of physiology. Heart and circulatory physiology 2001;281(6):H2619-25.
2001: Takeda K; Ichiki T; Tokunou T; Iino N; Takeshita A
15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.
The Journal of biological chemistry 2001;276(52):48950-5.
2001: Oyama J; Shimokawa H; Morita S; Yasui H; Takeshita A
Elevated interleukin-1beta in pericardial fluid of patients with ischemic heart disease.
Coronary artery disease 2001;12(7):567-71.
2001: Tokunou T; Ichiki T; Takeda K; Funakoshi Y; Iino N; Takeshita A
cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1764-9.
2001: Tokunou T; Ichiki T; Takeda K; Funakoshi Y; Iino N; Shimokawa H; Egashira K; Takeshita A
Thrombin induces interleukin-6 expression through the cAMP response element in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(11):1759-63.
2001: Kishi T; Hirooka Y; Sakai K; Shigematsu H; Shimokawa H; Takeshita A
Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release.
Hypertension 2001;38(4):896-901.
2001: Tsuchihashi M; Tsutsui H; Kodama K; Kasagi F; Setoguchi S; Mohr M; Kubota T; Takeshita A
Medical and socioenvironmental predictors of hospital readmission in patients with congestive heart failure.
American heart journal 2001;142(4):E7.
2001: Mukai Y; Tsutsui H; Todaka K; Mohri M; Hirai N; Arai H; Takeshita A
Total occlusion of inferior vena cava in a patient with antiphospholipid antibody syndrome associated with behçet's disease.
Japanese circulation journal 2001;65(9):837-8.
2001: Tada H; Egashira K; Yamamoto M; Usui M; Arai Y; Katsuda Y; Shimokawa H; Takeshita A
Role of nitric oxide in regulation of coronary blood flow in response to increased metabolic demand in dogs with pacing-induced heart failure.
Japanese circulation journal 2001;65(9):827-33.
2001: Tsutsui H; Tsuchihashi M; Takeshita A
Mortality and readmission of hospitalized patients with congestive heart failure and preserved versus depressed systolic function.
The American journal of cardiology 2001;88(5):530-3.
2001: Ni W; Egashira K; Kataoka C; Kitamoto S; Koyanagi M; Inoue S; Takeshita A
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.
Circulation research 2001;89(5):415-21.
2001: Washio M; Sasazuki S; Kodama H; Yoshimasu P K; Liu Y; Tanaka K; Tokunaga S; Kono P S; Arai H; Koyanagi S; Hiyamuta K; Doi Y; Kawano M T; Nakagaki M O; Takada K; Nii M T; Shirai K; Ideishi M M; Arakawa M K; Mohri M M; Takeshita A
Role of hypertension, dyslipidemia and diabetes mellitus in the development of coronary atherosclerosis in Japan.
Japanese circulation journal 2001;65(8):731-7.
2001: Setoguchi S; Mohri M; Shimokawa H; Takeshita A
Tetrahydrobiopterin improves endothelial dysfunction in coronary microcirculation in patients without epicardial coronary artery disease.
Journal of the American College of Cardiology 2001;38(2):493-8.
2001: Suematsu N; Satoh S; Kinugawa S; Tsutsui H; Hayashidani S; Nakamura R; Egashira K; Makino N; Takeshita A
Alpha1-adrenoceptor-Gq-RhoA signaling is upregulated to increase myofibrillar Ca2+ sensitivity in failing hearts.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H637-46.
2001: Funakoshi Y; Ichiki T; Shimokawa H; Egashira K; Takeda K; Kaibuchi K; Takeya M; Yoshimura T; Takeshita A
Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells.
Hypertension 2001;38(1):100-4.
2001: Tsutsui H; Ide T; Hayashidani S; Suematsu N; Shiomi T; Wen J; Nakamura Ki; Ichikawa K; Utsumi H; Takeshita A
Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure.
Circulation 2001;104(2):134-6.
2001: Shimokawa H; Morishige K; Miyata K; Kandabashi T; Eto Y; Ikegaki I; Asano T; Kaibuchi K; Takeshita A
Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo.
Cardiovascular research 2001;51(1):169-77.
2001: Hirooka Y; Sakai K; Kishi T; Takeshita A
Adenovirus-mediated gene transfer into the NTS in conscious rats. A new approach to examining the central control of cardiovascular regulation.
Annals of the New York Academy of Sciences 2001;940():197-205.
2001: Tsutsui H; Ide T; Hayashidani S; Kinugawa S; Suematsu N; Utsumi H; Takeshita A
Effects of ACE inhibition on left ventricular failure and oxidative stress in Dahl salt-sensitive rats.
Journal of cardiovascular pharmacology 2001;37(6):725-33.
2001: Shigematsu H; Hirooka Y; Eshima K; Shihara M; Tagawa T; Takeshita A
Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(6):R1665-73.
2001: Hirooka Y; Takeshita A
[Recent trends in studies of the etiology of hypertension: Central nervous system and autonomic nervous system]
Nippon rinsho. Japanese journal of clinical medicine 2001;59(5):860-6.
2001: Liu Y; Tanaka H; Sasazuki S; Yoshimasu K; Kodama H; Washio M; Tanaka K; Tokunaga S; Kono S; Arai H; Koyanagi S; Hiyamuta K; Doi Y; Kawano T; Nakagaki O; Takada K; Nii T; Shirai K; Ideishi M; Arakawa K; Mohri M; Takeshita A
Alcohol consumption and severity of angiographically determined coronary artery disease in Japanese men and women.
Atherosclerosis 2001;156(1):177-83.
2001: Takeda K; Ichiki T; Tokunou T; Iino N; Fujii S; Kitabatake A; Shimokawa H; Takeshita A
Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(5):868-73.
2001: Katoh M; Egashira K; Kataoka C; Usui M; Koyanagi M; Kitamoto S; Ohmachi Y; Takeshita A; Narita H
Regression by ACE inhibition of arteriosclerotic changes induced by chronic blockade of NO synthesis in rats.
American journal of physiology. Heart and circulatory physiology 2001;280(5):H2306-12.
2001: Matsuo I; Hirooka Y; Hironaga K; Eshima K; Shigematsu H; Shihara M; Sakai K; Takeshita A
Glutamate release via NO production evoked by NMDA in the NTS enhances hypotension and bradycardia in vivo.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(5):R1285-91.
2001: Ni W; Egashira K; Kitamoto S; Kataoka C; Koyanagi M; Inoue S; Imaizumi K; Akiyama C; Nishida K I; Takeshita A
New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout mice.
Circulation 2001;103(16):2096-101.
2001: Morishige K; Shimokawa H; Eto Y; Kandabashi T; Miyata K; Matsumoto Y; Hoshijima M; Kaibuchi K; Takeshita A
Adenovirus-mediated transfer of dominant-negative rho-kinase induces a regression of coronary arteriosclerosis in pigs in vivo.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(4):548-54.
2001: Mukai Y; Shimokawa H; Matoba T; Kandabashi T; Satoh S; Hiroki J; Kaibuchi K; Takeshita A
Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1062-4.
2001: Shihara M; Hirooka Y; Eshima K; Hori N; Takeshita A
Stimulatory effect of endothelin-1 on neurons in the nucleus tractus solitarii is mediated by non-N-methyl-D-aspartate receptors.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(2):137-42.
2001: Ide T; Tsutsui H; Hayashidani S; Kang D; Suematsu N; Nakamura K; Utsumi H; Hamasaki N; Takeshita A
Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction.
Circulation research 2001;88(5):529-35.
2001: Tanaka K; Kodama H; Sasazuki S; Yoshimasu K; Liu Y; Washio M; Tokunaga S; Kono S; Arai H; Koyanagi S; Hiyamuta K; Doi Y; Kawano T; Nakagaki O; Takada K; Nii T; Shirai K; Ideishi M; Arakawa K; Mohri M; Takeshita A
Obesity, body fat distribution and coronary atherosclerosis among Japanese men and women.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(2):191-7.
2001: Ichiki T; Takeda K; Tokunou T; Funakoshi Y; Ito K; Iino N; Takeshita A
Reactive oxygen species-mediated homologous downregulation of angiotensin II type 1 receptor mRNA by angiotensin II.
Hypertension 2001;37(2 Part 2):535-40.
2001: Atsuchi N; Nishida T; Marutsuka K; Asada Y; Kamikubo Y; Takeshita A; Ueno H
Combination of a brief irrigation with tissue factor pathway inhibitor (TFPI) and adenovirus-mediated local TFPI gene transfer additively reduces neointima formation in balloon-injured rabbit carotid arteries.
Circulation 2001;103(4):570-5.
2001: Tsutsui H; Kinugawa S; Ide T; Hayashidani S; Suematsu N; Satoh S; Nakamura R; Egashira K; Takeshita A
Positive inotropic effects of calcium sensitizers on normal and failing cardiac myocytes.
Journal of cardiovascular pharmacology 2001;37(1):16-24.
2001: Arimura K; Egashira K; Nakamura R; Ide T; Tsutsui H; Shimokawa H; Takeshita A
Increased inactivation of nitric oxide is involved in coronary endothelial dysfunction in heart failure.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H68-75.
2001: Tsutsui H; Ide T; Hayashidani S; Suematsu N; Utsumi H; Nakamura R; Egashira K; Takeshita A
Greater susceptibility of failing cardiac myocytes to oxygen free radical-mediated injury.
Cardiovascular research 2001;49(1):103-9.
2000: Tsuchihashi M; Tsutsui H; Kodama K; Kasagi F; Takeshita A
Clinical characteristics and prognosis of hospitalized patients with congestive heart failure--a study in Fukuoka, Japan.
Japanese circulation journal 2000;64(12):953-9.
2000: Kitamoto S; Egashira K; Kataoka C; Usui M; Koyanagi M; Takemoto M; Takeshita A
Chronic inhibition of nitric oxide synthesis in rats increases aortic superoxide anion production via the action of angiotensin II.
Journal of hypertension 2000;18(12):1795-800.
2000: Matoba T; Shimokawa H; Nakashima M; Hirakawa Y; Mukai Y; Hirano K; Kanaide H; Takeshita A
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice.
The Journal of clinical investigation 2000;106(12):1521-30.
2000: Sakai K; Hirooka Y; Matsuo I; Eshima K; Shigematsu H; Shimokawa H; Takeshita A
Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo.
Hypertension 2000;36(6):1023-8.
2000: Tokunaga S; Nakano T; Tominaga R; Imaizumi T; Takeshita A; Yasui H
Effects of nonpulsatile left heart bypass on renal sympathetic nerve activity in rabbits.
Perfusion 2000;15(6):515-20.
2000: Yogo K; Shimokawa H; Funakoshi H; Kandabashi T; Miyata K; Okamoto S; Egashira K; Huang P; Akaike T; Takeshita A
Different vasculoprotective roles of NO synthase isoforms in vascular lesion formation in mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):E96-E100.
2000: Miyata K; Shimokawa H; Kandabashi T; Higo T; Morishige K; Eto Y; Egashira K; Kaibuchi K; Takeshita A
Rho-kinase is involved in macrophage-mediated formation of coronary vascular lesions in pigs in vivo.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2351-8.
2000: Koyanagi M; Egashira K; Kitamoto S; Ni W; Shimokawa H; Takeya M; Yoshimura T; Takeshita A
Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis.
Circulation 2000;102(18):2243-8.
2000: Egashira K; Koyanagi M; Kitamoto S; Ni W; Kataoka C; Morishita R; Kaneda Y; Akiyama C; Nishida K I; Sueishi K; Takeshita A
Anti-monocyte chemoattractant protein-1 gene therapy inhibits vascular remodeling in rats: blockade of MCP-1 activity after intramuscular transfer of a mutant gene inhibits vascular remodeling induced by chronic blockade of NO synthesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):1974-8.
2000: Takeda K; Ichiki T; Tokunou T; Funakoshi Y; Iino N; Hirano K; Kanaide H; Takeshita A
Peroxisome proliferator-activated receptor gamma activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells.
Circulation 2000;102(15):1834-9.
2000: Yamamoto M; Egashira K; Arimura K; Tada H; Shimokawa H; Takeshita A
Coronary vascular K+ATP channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure.
Japanese circulation journal 2000;64(9):701-7.
2000: Kinugawa S; Tsutsui H; Hayashidani S; Ide T; Suematsu N; Satoh S; Utsumi H; Takeshita A
Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress.
Circulation research 2000;87(5):392-8.
2000: Sasazuki S; Kodama H; Yoshimasu K; Liu Y; Washio M; Tanaka K; Tokunaga S; Kono S; Arai H; Doi Y; Kawano T; Nakagaki O; Takada K; Koyanagi S; Hiyamuta K; Nii T; Shirai K; Ideishi M; Arakawa K; Mohri M; Takeshita A
Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women.
Annals of epidemiology 2000;10(6):401-8.
2000: Eshima K; Hirooka Y; Shigematsu H; Matsuo I; Koike G; Sakai K; Takeshita A
Angiotensin in the nucleus tractus solitarii contributes to neurogenic hypertension caused by chronic nitric oxide synthase inhibition.
Hypertension 2000;36(2):259-63.
2000: Kitamoto S; Egashira K; Kataoka C; Koyanagi M; Katoh M; Shimokawa H; Morishita R; Kaneda Y; Sueishi K; Takeshita A
Increased activity of nuclear factor-kappaB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats.
Circulation 2000;102(7):806-12.
2000: Yoshimasu K; Liu Y; Kodama H; Sasazuki S; Washio M; Tanaka K; Tokunaga S; Kono S; Arai H; Koyanagi S; Hiyamuta K; Doi Y; Kawano T; Nakagaki O; Takada K; Nii T; Shirai K; Ideishi M; Arakawa K; Mohri M; Takeshita A
Job strain, Type A behavior pattern, and the prevalence of coronary atherosclerosis in Japanese working men.
Journal of psychosomatic research 2000;49(1):77-83.
2000: Egashira K; Ni W; Inoue S; Kataoka C; Kitamoto S; Koyanagi M; Takeshita A
Pravastatin attenuates cardiovascular inflammatory and proliferative changes in a rat model of chronic inhibition of nitric oxide synthesis by its cholesterol-lowering independent actions.
Hypertension research : official journal of the Japanese Society of Hypertension 2000;23(4):353-8.
2000: Eto Y; Shimokawa H; Hiroki J; Morishige K; Kandabashi T; Matsumoto Y; Amano M; Hoshijima M; Kaibuchi K; Takeshita A
Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H1744-50.
2000: Katoh M; Egashira K; Mitsui T; Takeshita A; Narita H
Differential effects of imidapril and candesartan cilexetil on plasminogen activator inhibitor-1 expression induced by prolonged inhibition of nitric oxide synthesis in rat hearts.
Journal of cardiovascular pharmacology 2000;35(6):932-6.
2000: Kuga T; Shimokawa H; Hirakawa Y; Kadokami Y; Arai Y; Fukumoto Y; Kuwata K; Kozai T; Egashira K; Takeshita A
Increased expression of L-type calcium channels in vascular smooth muscle cells at spastic site in a porcine model of coronary artery spasm.
Journal of cardiovascular pharmacology 2000;35(5):822-8.
2000: Morishige K; Shimokawa H; Yamawaki T; Miyata K; Eto Y; Kandabashi T; Yogo K; Higo T; Egashira K; Ueno H; Takeshita A
Local adenovirus-mediated transfer of C-type natriuretic peptide suppresses vascular remodeling in porcine coronary arteries in vivo.
Journal of the American College of Cardiology 2000;35(4):1040-7.
2000: Kandabashi T; Shimokawa H; Miyata K; Kunihiro I; Kawano Y; Fukata Y; Higo T; Egashira K; Takahashi S; Kaibuchi K; Takeshita A
Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta.
Circulation 2000;101(11):1319-23.
2000: Ichiki T; Funakoshi Y; Ito K; Takeshita A
Expression of monocyte chemoattractant protein-1 by nonenzymatically glycated albumin (Amadori adducts) in vascular smooth muscle cells.
Biochemical and biophysical research communications 2000;269(3):666-70.
2000: Miyata K; Shimokawa H; Higo T; Yamawaki T; Katsumata N; Kandabashi T; Tanaka E; Takamura Y; Yogo K; Egashira K; Takeshita A
Sarpogrelate, a selective 5-HT2A serotonergic receptor antagonist, inhibits serotonin-induced coronary artery spasm in a porcine model.
Journal of cardiovascular pharmacology 2000;35(2):294-301.
2000: Mohri M; Tagawa H; Egashira K; Takeshita A
Intracoronary enalaprilat improves metabolic coronary vasodilation in patients with idiopathic dilated cardiomyopathy.
Journal of cardiovascular pharmacology 2000;35(2):249-55.
2000: Ide T; Tsutsui H; Kinugawa S; Suematsu N; Hayashidani S; Ichikawa K; Utsumi H; Machida Y; Egashira K; Takeshita A
Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium.
Circulation research 2000;86(2):152-7.
2000: Hirooka Y; Takeshita A
[Blood pressure regulation by nitric oxide within the brain]
Nippon rinsho. Japanese journal of clinical medicine 2000;58 Suppl 1():35-8.
2000: Katoh M; Egashira K; Mitsui T; Chishima S; Takeshita A; Narita H
Angiotensin-converting enzyme inhibitor prevents plasminogen activator inhibitor-1 expression in a rat model with cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis.
Journal of molecular and cellular cardiology 2000;32(1):73-83.
2000: Ueno H; Sakamoto T; Nakamura T; Qi Z; Astuchi N; Takeshita A; Shimizu K; Ohashi H
A soluble transforming growth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats.
Human gene therapy 2000;11(1):33-42.
2000: Usui M; Egashira K; Tomita H; Koyanagi M; Katoh M; Shimokawa H; Takeya M; Yoshimura T; Matsushima K; Takeshita A
Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats.
Circulation 2000;101(3):305-10.
2000: Takeda K; Ichiki T; Funakoshi Y; Ito K; Takeshita A
Downregulation of angiotensin II type 1 receptor by all-trans retinoic acid in vascular smooth muscle cells.
Hypertension 2000;35(1 Pt 2):297-302.
2000: Koyanagi M; Egashira K; Kubo-Inoue M; Usui M; Kitamoto S; Tomita H; Shimokawa H; Takeshita A
Role of transforming growth factor-beta1 in cardiovascular inflammatory changes induced by chronic inhibition of nitric oxide synthesis.
Hypertension 2000;35(1 Pt 1):86-90.
1999: Kinugawa S; Tsutsui H; Satoh S; Takahashi M; Ide T; IgarashiSaito K; Arimura K; Egashira K; Takeshita A
Role of Ca2+ availability to myofilaments and their sensitivity to Ca2+ in myocyte contractile dysfunction in heart failure.
Cardiovascular research 1999;44(2):398-406.
1999: Usui M; Egashira K; Kitamoto S; Koyanagi M; Katoh M; Kataoka C; Shimokawa H; Takeshita A
Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats.
Hypertension 1999;34(4 Pt 1):546-51.
1999: Shimokawa H; Seto M; Katsumata N; Amano M; Kozai T; Yamawaki T; Kuwata K; Kandabashi T; Egashira K; Ikegaki I; Asano T; Kaibuchi K; Takeshita A
Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm.
Cardiovascular research 1999;43(4):1029-39.
1999: Miyata K; Shimokawa H; Yamawaki T; Kunihiro I; Zhou X; Higo T; Tanaka E; Katsumata N; Egashira K; Takeshita A
Endothelial vasodilator function is preserved at the spastic/inflammatory coronary lesions in pigs.
Circulation 1999;100(13):1432-7.
1999: Takamura Y; Shimokawa H; Zhao H; Igarashi H; Egashira K; Takeshita A
Important role of endothelium-derived hyperpolarizing factor in shear stress--induced endothelium-dependent relaxations in the rat mesenteric artery.
Journal of cardiovascular pharmacology 1999;34(3):381-7.
1999: Igarashi-Saito K; Tsutsui H; Takahashi M; Kinugawa S; Egashira K; Takeshita A
Endocardial versus epicardial differences of sarcoplasmic reticulum Ca2+-ATPase gene expression in the canine failing myocardium.
Basic research in cardiology 1999;94(4):267-73.
1999: Ide T; Tsutsui H; Kinugawa S; Utsumi H; Kang D; Hattori N; Uchida K; Arimura K i; Egashira K; Takeshita A
Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium.
Circulation research 1999;85(4):357-63.
1999: Ide T; Tsutsui H; Kinugawa S; Utsumi H; Takeshita A
Amiodarone protects cardiac myocytes against oxidative injury by its free radical scavenging action.
Circulation 1999;100(7):690-2.
1999: Yamamoto H; Atsuchi N; Tanaka H; Ogawa W; Abe M; Takeshita A; Ueno H
Separate roles for H-Ras and Rac in signaling by transforming growth factor (TGF)-beta. H-Ras is essential for activation of MAP kinase, partially required for transcriptional activation by TGF-beta, but not required for signaling of growth suppression by TGF-beta.
European journal of biochemistry / FEBS 1999;264(1):110-9.
1999: Kinugawa S; Tsutsui H; Ide T; Nakamura R; Arimura K; Egashira K; Takeshita A
Positive inotropic effect of insulin-like growth factor-1 on normal and failing cardiac myocytes.
Cardiovascular research 1999;43(1):157-64.
1999: Funakoshi Y; Ichiki T; Ito K; Takeshita A
Induction of interleukin-6 expression by angiotensin II in rat vascular smooth muscle cells.
Hypertension 1999;34(1):118-25.
1999: Cheng X S; Shimokawa H; Momii H; Oyama J; Fukuyama N; Egashira K; Nakazawa H; Takeshita A
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Cardiovascular research 1999;42(3):651-9.
1999: Nishida T; Ueno H; Atsuchi N; Kawano R; Asada Y; Nakahara Y; Kamikubo Y i; Takeshita A; Yasui H
Adenovirus-mediated local expression of human tissue factor pathway inhibitor eliminates shear stress-induced recurrent thrombosis in the injured carotid artery of the rabbit.
Circulation research 1999;84(12):1446-52.
1999: Tsutsui H; Ishibashi Y; Takahashi M; Namba T; Tagawa H; Imanaka-Yoshida K; Takeshita A
Chronic colchicine administration attenuates cardiac hypertrophy in spontaneously hypertensive rats.
Journal of molecular and cellular cardiology 1999;31(6):1203-13.
1999: Tagawa H; Shimokawa H; Tagawa T; Kuroiwa-Matsumoto M; Hirooka Y; Takeshita A
Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease.
Journal of cardiovascular pharmacology 1999;33(4):633-40.
1999: Zhao H; Shimokawa H; Uragami-Harasawa L; Igarashi H; Takeshita A
Long-term vascular effects of Nomega-nitro-L-arginine methyl ester are not soley mediated by inhibition of endothelial nitric oxide synthesis in the rat mesenteric artery.
Journal of cardiovascular pharmacology 1999;33(4):554-66.
1999: Shihara M; Hori N; Hirooka Y; Eshima K; Akaike N; Takeshita A
Cholinergic systems in the nucleus of the solitary tract of rats.
The American journal of physiology 1999;276(4 Pt 2):R1141-8.
1999: Satoh S; Kinugawa S; Tsutsui H; Takeshita A
Adrenoceptor-mediated regulation of myofibrillar Ca2+ sensitivity through the GTP-binding protein-related mechanisms: tension recording in beta-escin-skinned single rat cardiac cells with preserved receptor functions.
Pflügers Archiv : European journal of physiology 1999;437(5):702-9.
1999: Mohri M; Takeshita A
Coronary microvascular disease in humans.
Japanese heart journal 1999;40(2):97-108.
1999: Hirooka Y; Shihara M; Eshima K; Hori N; Takeshita A
Endothelin-1 facilitates synaptic transmission in the nucleus tractus solitarii in normotensive rats but not in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(1):43-8.
1999: Qi Z; Atsuchi N; Ooshima A; Takeshita A; Ueno H
Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2345-9.
1999: Sadamatsu K; Urabe Y; Tsutsui H; Tagawa H; Maruoka F; Igarashi-Saito K; Takeda K; Kawachi Y; Yasui H; Takeshita A
Sarcoplasmic reticulum Ca2+ regulatory protein gene expression in human right atrium under hemodynamic overload.
Heart and vessels 1999;14(5):208-15.
1998: Momii H; Shimokawa H; Oyama J; Cheng X S; Nakamura R; Egashira K; Nakazawa H; Takeshita A
Inhibition of adhesion molecules markedly ameliorates cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Journal of molecular and cellular cardiology 1998;30(12):2637-50.
1998: Shimokawa H; Kuroiwa-Matsumoto M; Takeshita A
Cytokine generation capacities of monocytes are reduced in patients with severe heart failure.
American heart journal 1998;136(6):991-1002.
1998: Katoh M; Egashira K; Usui M; Ichiki T; Tomita H; Shimokawa H; Rakugi H; Takeshita A
Cardiac angiotensin II receptors are upregulated by long-term inhibition of nitric oxide synthesis in rats.
Circulation research 1998;83(7):743-51.
1998: Yamamoto S; Tsutsui H; Takahashi M; Ishibashi Y; Tagawa H; Imanaka-Yoshida K; Saeki Y; Takeshita A
Role of microtubules in the viscoelastic properties of isolated cardiac muscle.
Journal of molecular and cellular cardiology 1998;30(9):1841-53.
1998: Tomita H; Egashira K; Kubo-Inoue M; Usui M; Koyanagi M; Shimokawa H; Takeya M; Yoshimura T; Takeshita A
Inhibition of NO synthesis induces inflammatory changes and monocyte chemoattractant protein-1 expression in rat hearts and vessels.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(9):1456-64.
1998: Yamawaki T; Shimokawa H; Kozai T; Miyata K; Higo T; Tanaka E; Egashira K; Shiraishi T; Tamai H; Igaki K; Takeshita A
Intramural delivery of a specific tyrosine kinase inhibitor with biodegradable stent suppresses the restenotic changes of the coronary artery in pigs in vivo.
Journal of the American College of Cardiology 1998;32(3):780-6.
1998: Usui M; Ichiki T; Katoh M; Egashira K; Takeshita A
Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland.
Hypertension 1998;32(3):527-33.
1998: Tomita H; Egashira K; Ohara Y; Takemoto M; Koyanagi M; Katoh M; Yamamoto H; Tamaki K; Shimokawa H; Takeshita A
Early induction of transforming growth factor-beta via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats.
Hypertension 1998;32(2):273-9.
1998: Shihara M; Hirooka Y; Hori N; Matsuo I; Tagawa T; Suzuki S; Akaike N; Takeshita A
Endothelin-1 increases the neuronal activity and augments the responses to glutamate in the NTS.
The American journal of physiology 1998;275(2 Pt 2):R658-65.
1998: Takahashi M; Tsutsui H; Tagawa H; Igarashi-Saito K; Imanaka-Yoshida K; Takeshita A
Microtubules are involved in early hypertrophic responses of myocardium during pressure overload.
The American journal of physiology 1998;275(2 Pt 2):H341-8.
1998: Lai C P; Koyanagi S; Shaw C K; Takeshita A
Evaluation of the early stage of carotid atherosclerosis using the vascular response to nitroglycerin and high-resolution ultrasonography.
Japanese circulation journal 1998;62(7):494-8.
1998: Igarashi-Saito K; Tsutsui H; Yamamoto S; Takahashi M; Kinugawa S; Tagawa H; Usui M; Yamamoto M; Egashira K; Takeshita A
Role of SR Ca2+-ATPase in contractile dysfunction of myocytes in tachycardia-induced heart failure.
The American journal of physiology 1998;275(1 Pt 2):H31-40.
1998: Takahashi M; Tsutsui H; Kinugawa S; Igarashi-Saito K; Yamamoto S; Yamamoto M; Tagawa H; Imanaka-Yoshida K; Egashira K; Takeshita A
Role of microtubules in the contractile dysfunction of myocytes from tachycardia-induced dilated cardiomyopathy.
Journal of molecular and cellular cardiology 1998;30(5):1047-57.
1998: Oyama J i; Shimokawa H; Momii H; Cheng X; Fukuyama N; Arai Y; Egashira K; Nakazawa H; Takeshita A
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
The Journal of clinical investigation 1998;101(10):2207-14.
1998: Mohri M; Koyanagi M; Egashira K; Tagawa H; Ichiki T; Shimokawa H; Takeshita A
Angina pectoris caused by coronary microvascular spasm.
Lancet 1998;351(9110):1165-9.
1998: Ichiki T; Usui M; Kato M; Funakoshi Y; Ito K; Egashira K; Takeshita A
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide.
Hypertension 1998;31(1 Pt 2):342-8.
1998: Hironaga K; Hirooka Y; Matsuo I; Shihara M; Tagawa T; Harasawa Y; Takeshita A
Role of endogenous nitric oxide in the brain stem on the rapid adaptation of baroreflex.
Hypertension 1998;31(1):27-31.
1997: Katsumata N; Shimokawa H; Seto M; Kozai T; Yamawaki T; Kuwata K; Egashira K; Ikegaki I; Asano T; Sasaki Y; Takeshita A
Enhanced myosin light chain phosphorylations as a central mechanism for coronary artery spasm in a swine model with interleukin-1beta.
Circulation 1997;96(12):4357-63.
1997: Mohri M; Egashira K; Kuga T; Shimokawa H; Takeshita A
Correlations between recruitable coronary collateral flow velocities, distal occlusion pressure, and electrocardiographic changes in patients undergoing angioplasty.
Japanese circulation journal 1997;61(12):971-8.
1997: Takemoto M; Egashira K; Tomita H; Usui M; Okamoto H; Kitabatake A; Shimokawa H; Sueishi K; Takeshita A
Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis.
Hypertension 1997;30(6):1621-7.
1997: Urakami-Harasawa L; Shimokawa H; Nakashima M; Egashira K; Takeshita A
Importance of endothelium-derived hyperpolarizing factor in human arteries.
The Journal of clinical investigation 1997;100(11):2793-9.
1997: Ueno H; Li J J; Masuda S; Qi Z; Yamamoto H; Takeshita A
Adenovirus-mediated expression of the secreted form of basic fibroblast growth factor (FGF-2) induces cellular proliferation and angiogenesis in vivo.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2453-60.
1997: Fukumoto Y; Shimokawa H; Kozai T; Kadokami T; Kuwata K; Yonemitsu Y; Kuga T; Egashira K; Sueishi K; Takeshita A
Vasculoprotective role of inducible nitric oxide synthase at inflammatory coronary lesions induced by chronic treatment with interleukin-1beta in pigs in vivo.
Circulation 1997;96(9):3104-11.
1997: Alpaslan M; Shimokawa H; Kuroiwa-Matsumoto M; Harasawa Y; Takeshita A
Short-term estrogen administration ameliorates dobutamine-induced myocardial ischemia in postmenopausal women with coronary artery disease.
Journal of the American College of Cardiology 1997;30(6):1466-71.
1997: Tokunaga S; Imaizumi T; Kawachi Y; Fukae K; Tominaga R; Takeshita A; Yasui H
Mechanism of abrupt hypotension with stretch of right atrium during cardiac surgery.
Cardiovascular surgery (London, England) 1997;5(5):539-46.
1997: Ishibashi Y; Urabe Y; Tsutsui H; Kinugawa S; Sugimachi M; Takahashi M; Yamamoto S; Tagawa H; Sunagawa K; Takeshita A
Negative inotropic effect of basic fibroblast growth factor on adult rat cardiac myocyte.
Circulation 1997;96(8):2501-4.
1997: Ueno H; Haruno A; Morisaki N; Furuya M; Kangawa K; Takeshita A; Saito Y
Local expression of C-type natriuretic peptide markedly suppresses neointimal formation in rat injured arteries through an autocrine/paracrine loop.
Circulation 1997;96(7):2272-9.
1997: Tagawa H; Shimokawa H; Tagawa T; Kuroiwa-Matsumoto M; Hirooka Y; Takeshita A
Short-term estrogen augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilation in postmenopausal women.
Journal of cardiovascular pharmacology 1997;30(4):481-8.
1997: Tada H; Egashira K; Yamamoto M; Ueno H; Takemoto M; Shimokawa H; Takeshita A
Glibenclamide, a specific inhibitor of ATP-sensitive K+ channels, inhibits coronary vasodilation induced by angiotensin II-receptor antagonists.
Journal of cardiovascular pharmacology 1997;30(3):313-9.
1997: Kozai T; Shimokawa H; Yamawaki T; Fukumoto Y; Kadokami T; Kuwata K; Katsumata N; Egashira K; Takeshita A
Platelet activating factor causes hyperconstriction at the inflammatory coronary lesions in pigs in vivo.
Coronary artery disease 1997;8(7):423-32.
1997: Mohri M; Egashira K; Tagawa T; Kuga T; Tagawa H; Harasawa Y; Shimokawa H; Takeshita A
Basal release of nitric oxide is decreased in the coronary circulation in patients with heart failure.
Hypertension 1997;30(1 Pt 1):50-6.
1997: Kuga T; Mohri M; Egashira K; Hirakawa Y; Tagawa T; Shimokawa H; Takeshita A
Bradykinin-induced vasodilation of human coronary arteries in vivo: role of nitric oxide and angiotensin-converting enzyme.
Journal of the American College of Cardiology 1997;30(1):108-12.
1997: Kubota T; Imaizumi T; Oyama J; Ando S; Takeshita A
L-arginine increases exercise-induced vasodilation of the forearm in patients with heart failure.
Japanese circulation journal 1997;61(6):471-80.
1997: Namba T; Tsutsui H; Tagawa H; Takahashi M; Saito K; Kozai T; Usui M; Imanaka-Yoshida K; Imaizumi T; Takeshita A
Regulation of fibrillar collagen gene expression and protein accumulation in volume-overloaded cardiac hypertrophy.
Circulation 1997;95(10):2448-54.
1997: Ueno H; Yamamoto H; Ito S; Li J J; Takeshita A
Adenovirus-mediated transfer of a dominant-negative H-ras suppresses neointimal formation in balloon-injured arteries in vivo.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(5):898-904.
1997: Ueno H; Masuda S; Nishio S; Li J J; Yamamoto H; Takeshita A
Adenovirus-mediated transfer of cyclin-dependent kinase inhibitor-p21 suppresses neointimal formation in the balloon-injured rat carotid arteries in vivo.
Annals of the New York Academy of Sciences 1997;811():401-11.
1997: Tagawa T; Mohri M; Tagawa H; Egashira K; Shimokawa H; Kuga T; Hirooka Y; Takeshita A
Role of nitric oxide in substance P-induced vasodilation differs between the coronary and forearm circulation in humans.
Journal of cardiovascular pharmacology 1997;29(4):546-53.
1997: Kozai T; Shimokawa H; Fukumoto Y; Kobayashi S; Owada M K; Kadokami T; Ito A; Kuwata K; Egashira K; Shiraishi T; Kanaide H; Takeshita A
Tyrosine kinase inhibitor markedly suppresses the development of coronary lesions induced by long-term treatment with platelet-derived growth factor in pigs in vivo.
Journal of cardiovascular pharmacology 1997;29(4):536-45.
1997: Yamamoto S; Tsutsui H; Tagawa H; Saito K; Takahashi M; Tada H; Yamamoto M; Katoh M; Egashira K; Takeshita A
Role of myocyte nitric oxide in beta-adrenergic hyporesponsiveness in heart failure.
Circulation 1997;95(5):1111-4.
1997: Kuga T; Kadokami T; Kuwata K; Hata H; Ohara Y; Egashira K; Shimokawa H; Takeshita A
Central role of vascular smooth muscle hyperreactivity in coronary hyperconstriction after balloon injury in miniature pigs.
Coronary artery disease 1997;8(2):69-75.
1997: Shiramoto M; Imaizumi T; Hirooka Y; Endo T; Namba T; Oyama J; Hironaga K; Takeshita A
Role of nitric oxide towards vasodilator effects of substance P and ATP in human forearm vessels.
Clinical science (London, England : 1979) 1997;92(2):123-31.
1997: Fukumoto Y; Shimokawa H; Ito A; Kadokami T; Yonemitsu Y; Aikawa M; Owada M K; Egashira K; Sueishi K; Nagai R; Yazaki Y; Takeshita A
Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs.
Journal of cardiovascular pharmacology 1997;29(2):222-31.
1997: Tsutsui H; Ishibashi Y; Imanaka-Yoshida K; Yamamoto S; Yoshida T; Sugimachi M; Urabe Y; Takeshita A
Alterations in sarcoplasmic reticulum calcium-storing proteins in pressure-overload cardiac hypertrophy.
The American journal of physiology 1997;272(1 Pt 2):H168-75.
1997: Takemoto M; Egashira K; Usui M; Numaguchi K; Tomita H; Tsutsui H; Shimokawa H; Sueishi K; Takeshita A
Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats.
The Journal of clinical investigation 1997;99(2):278-87.
1996: Fukumoto Y; Shimokawa H; Kozai T; Kadokami T; Kuwata K; Owada M K; Shiraishi T; Kuga T; Egashira K; Takeshita A
Tyrosine kinase inhibitor suppresses the (re) stenotic changes of the coronary artery after balloon injury in pigs.
Cardiovascular research 1996;32(6):1131-40.
1996: Fukumoto Y; Urabe Y; Shimokawa H; Chishaki-Suyama A; Takeshita A
Slowing of ventricular rate quickly improved ventricular dysfunction and exercise intolerance in patients with chronic atrial tachycardia.
Fukuoka igaku zasshi = Hukuoka acta medica 1996;87(12):274-7.
1996: Takeshita A; Hirooka Y; Imaizumi T
Role of endothelium in control of forearm blood flow in patients with heart failure.
Journal of cardiac failure 1996;2(4 Suppl):S209-15.
1996: Ishibashi Y; Tsutsui H; Yamamoto S; Takahashi M; Imanaka-Yoshida K; Yoshida T; Urabe Y; Sugimachi M; Takeshita A
Role of microtubules in myocyte contractile dysfunction during cardiac hypertrophy in the rat.
The American journal of physiology 1996;271(5 Pt 2):H1978-87.
1996: Shimokawa H; Yasutake H; Fujii K; Owada M K; Nakaike R; Fukumoto Y; Takayanagi T; Nagao T; Egashira K; Fujishima M; Takeshita A
The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation.
Journal of cardiovascular pharmacology 1996;28(5):703-11.
1996: Ito A; Shimokawa H; Fukumoto Y; Kadokami T; Nakaike R; Takayanagi T; Egashira K; Sueishi K; Takeshita A
The role of fibroblast growth factor-2 in the vascular effects of interleukin-1 beta in porcine coronary arteries in vivo.
Cardiovascular research 1996;32(3):570-9.
1996: Kadokami T; Shimokawa H; Ito A; Mohri M; Takeshita A
Disappearance of coronary artery-ventricular fistulas after a radical operation for tetralogy of Fallot.
Japanese circulation journal 1996;60(8):624-7.
1996: Egashira K; Katsuda Y; Mohri M; Kuga T; Tagawa T; Kubota T; Hirakawa Y; Takeshita A
Role of endothelium-derived nitric oxide in coronary vasodilatation induced by pacing tachycardia in humans.
Circulation research 1996;79(2):331-5.
1996: Kuga T; Kobayashi S; Hirakawa Y; Kanaide H; Takeshita A
Cell cycle--dependent expression of L- and T-type Ca2+ currents in rat aortic smooth muscle cells in primary culture.
Circulation research 1996;79(1):14-9.
1996: Nakaike R; Shimokawa H; Owada M K; Tokunaga O; Yasutake H; Kishimoto T; Imada C; Shiraishi T; Egashira K; Takeshita A
Vanadate causes synthesis of endothelium-derived NO via pertussis toxin-sensitive G protein in pigs.
The American journal of physiology 1996;271(1 Pt 2):H296-302.
1996: Kadokami T; Shimokawa H; Fukumoto Y; Ito A; Takayanagi T; Egashira K; Takeshita A
Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1 beta in vivo.
Circulation 1996;94(2):190-6.
1996: Kadokami T; Egashira K; Kuwata K; Fukumoto Y; Kozai T; Yasutake H; Kuga T; Shimokawa H; Sueishi K; Takeshita A
Altered serotonin receptor subtypes mediate coronary microvascular hyperreactivity in pigs with chronic inhibition of nitric oxide synthesis.
Circulation 1996;94(2):182-9.
1996: Egashira K; Hirooka Y; Kuga T; Mohri M; Takeshita A
Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary arteriograms.
Circulation 1996;94(2):130-4.
1996: Yamamoto H; Ueno H; Ooshima A; Takeshita A
Adenovirus-mediated transfer of a truncated transforming growth factor-beta (TGF-beta) type II receptor completely and specifically abolishes diverse signaling by TGF-beta in vascular wall cells in primary culture.
The Journal of biological chemistry 1996;271(27):16253-9.
1996: Katsuda Y; Egashira K; Ueno H; Arai Y; Akatsuka Y; Kuga T; Shimokawa H; Takeshita A
ATP-sensitive K+ channel opener pinacidil augments beta 1-adrenoceptor-induced coronary vasodilation in dogs.
The American journal of physiology 1996;270(6 Pt 2):H2210-5.
1996: Numaguchi K; Shimokawa H; Nakaike R; Egashira K; Takeshita A
PKC inhibitors prevent endothelial dysfunction after myocardial ischemia-reperfusion in rats.
The American journal of physiology 1996;270(5 Pt 2):H1634-9.
1996: Tokunaga S; Imaizumi T; Fukae K; Nakashima A; Hisahara M; Tominaga R; Takeshita A; Yasui H; Tokunaga K
Effects of hypothermia during cardiopulmonary bypass and circulatory arrest on sympathetic nerve activity in rabbits.
Cardiovascular research 1996;31(5):769-76.
1996: Egashira K; Katsuda Y; Mohri M; Kuga T; Tagawa T; Shimokawa H; Takeshita A
Basal release of endothelium-derived nitric oxide at site of spasm in patients with variant angina.
Journal of the American College of Cardiology 1996;27(6):1444-9.
1996: Kubo T; Imaizumi T; Harasawa Y; Ando S; Tagawa T; Endo T; Shiramoto M; Takeshita A
Transfer function analysis of central arc of aortic baroreceptor reflex in rabbits.
The American journal of physiology 1996;270(3 Pt 2):H1054-62.
1996: Nakaike R; Urabe Y; Shimokawa H; Kinjoh M; Takeshita A
Recurrent myocardial infarction provoked by multiple giant coronary aneurysms. A case report.
Angiology 1996;47(3):311-4.
1996: Numaguchi K; Egashira K; Sakata M; Shimokawa H; Takeshita A
Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats.
Journal of hypertension 1996;14(2):183-9.
1996: Ando S; Usui M; Matsumoto T; Egashira K; Takeshita A; Terasaki F; Deguchi H; Kawamura K
Vasospastic angina in patients with systemic triglyceride storage disease with Jordans' anomaly and cardiomyopathy.
Japanese circulation journal 1996;60(2):124-9.
1996: Shimokawa H; Ito A; Fukumoto Y; Kadokami T; Nakaike R; Sakata M; Takayanagi T; Egashira K; Takeshita A
Chronic treatment with interleukin-1 beta induces coronary intimal lesions and vasospastic responses in pigs in vivo. The role of platelet-derived growth factor.
The Journal of clinical investigation 1996;97(3):769-76.
1996: Tsutsui H; Ando S; Kubota T; Kuroiwa-Matsumoto M; Egashira K; Sasaki M; Kuwabara Y; Koyanagi S; Yasui H; Takeshita A
Abnormalities of cardiac sympathetic neuronal and left ventricular function in chronic mitral regurgitation: assessment by iodine-123 metaiodobenzylguanidine scintigraphy.
American journal of cardiac imaging 1996;10(1):14-22.
1995: Momohara M; Imaizumi T; Endo T; Suzuki S; Tagawa T; Shiramoto M; Masaki H; Takeshita A
Central GABAergic mechanisms are defective in salt-induced hypertension in borderline hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18(4):285-93.
1995: Hata H; Kuga T; Takeshita A
Adherent leukocytes to the aortic wall promotes atherosclerosis in the Watanabe heritable hyperlipidemic rabbits.
Fukuoka igaku zasshi = Hukuoka acta medica 1995;86(12):437-42.
1995: Numaguchi K; Egashira K; Takemoto M; Kadokami T; Shimokawa H; Sueishi K; Takeshita A
Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats.
Hypertension 1995;26(6 Pt 1):957-62.
1995: Ueno H; Li J J; Tomita H; Yamamoto H; Pan Y; Kanegae Y; Saito I; Takeshita A
Quantitative analysis of repeat adenovirus-mediated gene transfer into injured canine femoral arteries.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(12):2246-53.
1995: Tashiro H; Koyanagi S; Takeshita A
Temporal variability in wall motion abnormality with stress-induced myocardial ischemia assessed by quantitative exercise echocardiography: difference between reversible and persistent myocardial ischemia.
American heart journal 1995;130(6):1189-95.
1995: Ito A; Egashira K; Kadokami T; Fukumoto Y; Takayanagi T; Nakaike R; Kuga T; Sueishi K; Shimokawa H; Takeshita A
Chronic inhibition of endothelium-derived nitric oxide synthesis causes coronary microvascular structural changes and hyperreactivity to serotonin in pigs.
Circulation 1995;92(9):2636-44.
1995: Fukai T; Koyanagi S; Tashiro H; Ichiki T; Tsutsui H; Matsumoto T; Takeshita A
Adenosine triphosphate stress echocardiography in the detection of myocardial ischemia.
American journal of cardiac imaging 1995;9(4):237-44.
1995: Shimokawa H; Takeshita A
Endothelium-dependent regulation of the cardiovascular system.
Internal medicine (Tokyo, Japan) 1995;34(10):939-46.
1995: Katsuda Y; Egashira K; Akatsuka Y; Narishige T; Shimokawa H; Takeshita A
Endothelium-derived nitric oxide does not modulate metabolic coronary vasodilation induced by tachycardia in dogs.
Journal of cardiovascular pharmacology 1995;26(3):437-44.
1995: Ito A; Shimokawa H; Kadokami T; Fukumoto Y; Owada M K; Shiraishi T; Nakaike R; Takayanagi T; Egashira K; Takeshita A
Tyrosine kinase inhibitor suppresses coronary arteriosclerotic changes and vasospastic responses induced by chronic treatment with interleukin-1 beta in pigs in vivo.
The Journal of clinical investigation 1995;96(3):1288-94.
1995: Fujishima S; Imaizumi T; Abe I; Takeshita A; Fujishima M
Effects of intra-arterial infusion of insulin on forearm vasoreactivity in hypertensive humans.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18(3):227-33.
1995: Katsuda Y; Egashira K; Ueno H; Akatsuka Y; Narishige T; Arai Y; Takayanagi T; Shimokawa H; Takeshita A
Glibenclamide, a selective inhibitor of ATP-sensitive K+ channels, attenuates metabolic coronary vasodilatation induced by pacing tachycardia in dogs.
Circulation 1995;92(3):511-7.
1995: Mitsuoka W; Egashira S; Tagawa H; Kuga T; Hayashi Y; Yamada A; Tomoike H; Nakamura M; Takeshita A
Augmentation of coronary responsiveness to serotonin at the site of X-ray-induced intimal thickening in miniature pigs.
Cardiovascular research 1995;30(2):246-54.
1995: Fukai T; Egashira K; Numaguchi K; Hata H; Takahashi T; Kasuya H; Sakata M; Shimokawa H; Takeshita A
Endothelin-1 is not involved in serotonin-induced coronary spasm in a swine model.
Cardiovascular research 1995;30(2):193-9.
1995: Kuga T; Egashira K; Mohri M; Tsutsui H; Harasawa Y; Urabe Y; Ando S; Shimokawa H; Takeshita A
Bradykinin-induced vasodilation is impaired at the atherosclerotic site but is preserved at the spastic site of human coronary arteries in vivo.
Circulation 1995;92(2):183-9.
1995: Li J J; Ueno H; Pan Y; Tomita H; Yamamoto H; Kanegae Y; Saito I; Takeshita A
Percutaneous transluminal gene transfer into canine myocardium in vivo by replication-defective adenovirus.
Cardiovascular research 1995;30(1):97-105.
1995: Hata H; Ohara Y; Kuga T; Fukai T; Kasuya H; Tomoike H; Takeshita A
Vasoreactivity and restenosis after coronary angioplasty in the atherosclerotic pig model.
Coronary artery disease 1995;6(6):503-11.
1995: Nakaike R; Shimokawa H; Yasutake H; Sumimoto H; Ito A; Numaguchi K; Egashira K; Takeshige K; Takeshita A
Effects of L-arginine analogues on vasomotion of isolated porcine coronary arteries.
The American journal of physiology 1995;268(5 Pt 2):H1966-72.
1995: Tsutsui H; Ando S; Fukai T; Kuroiwa M; Egashira K; Sasaki M; Kuwabara Y; Koyanagi S; Takeshita A
Detection of angina-provoking coronary stenosis by resting iodine 123 metaiodobenzylguanidine scintigraphy in patients with unstable angina pectoris.
American heart journal 1995;129(4):708-15.
1995: Tagawa T; Imaizumi T; Shiramoto M; Endo T; Hironaga K; Takeshita A
V2 receptor-mediated vasodilation in healthy humans.
Journal of cardiovascular pharmacology 1995;25(3):387-92.
1995: Egashira S; Mitsuoka W; Tagawa H; Kuga T; Tomoike H; Nakamura M; Takeshita A
Mechanisms of ergonovine-induced hyperconstriction of coronary artery after x-ray irradiation in pigs.
Basic research in cardiology 1995;90(2):167-75.
1995: Hirakawa Y; Kuga T; Kobayashi S; Kanaide H; Takeshita A
Dual regulation of L-type Ca2+ channels by serotonin 2 receptor stimulation in vascular smooth muscle cells.
The American journal of physiology 1995;268(2 Pt 2):H544-9.
1995: Kuga T; Ohara Y; Shimokawa H; Ibayashi S; Tomoike H; Takeshita A
Inhibitory effects of aspirin on coronary hyperreactivity to autacoids after arterial balloon injury in miniature pigs.
Journal of cardiovascular pharmacology 1995;25(2):273-81.
1995: Egashira K; Suzuki S; Hirooka Y; Kai H; Sugimachi M; Imaizumi T; Takeshita A
Impaired endothelium-dependent vasodilation of large epicardial and resistance coronary arteries in patients with essential hypertension. Different responses to acetylcholine and substance P.
Hypertension 1995;25(2):201-6.
1995: Egashira K; Takeshita A
Beneficial effect of cholesterol-lowering therapy on endothelium-dependent coronary vasodilation in patients with hypercholesterolemia.
Annals of the New York Academy of Sciences 1995;748():622-5.
1995: Numaguchi K; Egashira K; Inou T; Takeshita A
Immediate relief of spontaneous coronary artery spasm by intracoronary infusion of an endothelium-dependent vasodilator, substance P.
Japanese heart journal 1995;36(1):111-4.
1995: Shihara M; Harasawa Y; Ando S; Mohri M; Takeshita A
Isoproterenol infusion provokes vasovagal response without upright tilt in a patient exhibiting syncopal episodes.
Heart and vessels 1995;10(5):279-82.
1995: Shimokawa H; Nakaike R; Takeshita A
Significance of defective endothelial signal transduction in impaired endothelium-dependent relaxation in atherosclerosis.
Gerontology 1995;41 Suppl 1():28-33.
1995: Sadamatsu K; Harasawa Y; Ozono K; Yasutsune T; Masuda M; Kawachi Y; Yasui H; Takeshita A
A rare case of large ventricular septal defect with minimal pulmonary vascular obstructive changes in a 41-year-old woman.
Heart and vessels 1995;10(4):218-20.
1995: Hirakawa Y; Kuga T; Ohara Y; Hata H; Tomoike H; Takeshita A
Mechanisms of coronary hyperconstriction in response to serotonin induced by X-irradiation in miniature pigs: increased constrictive response of medial smooth muscle.
Heart and vessels 1995;10(4):190-6.
1994: Endo T; Imaizumi T; Tagawa T; Shiramoto M; Ando S; Takeshita A
Role of nitric oxide in exercise-induced vasodilation of the forearm.
Circulation 1994;90(6):2886-90.
1994: Kai H; Egashira K; Hirooka Y; Sugimachi M; Suzuki S; Kuga T; Mohri K; Urabe Y; Inou T; Takeshita A
Effects of intracoronary infusion of atrial natriuretic peptide on pacing-induced myocardial ischemia in patients with effort angina pectoris.
Coronary artery disease 1994;5(12):987-94.
1994: Tagawa T; Imaizumi T; Endo T; Shiramoto M; Harasawa Y; Takeshita A
Role of nitric oxide in reactive hyperemia in human forearm vessels.
Circulation 1994;90(5):2285-90.
1994: Koike G; Yamada A; Inou T; Urabe Y; Takeshita A
Percutaneous balloon valvuloplasty with a modified Inoue balloon for stenosis of a porcine bioprosthesis in the tricuspid valve position.
Japanese heart journal 1994;35(6):809-12.
1994: Ito A; Shimokawa H; Nakaike R; Fukai T; Sakata M; Takayanagi T; Egashira K; Takeshita A
Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model.
Circulation 1994;90(5):2425-31.
1994: Sakai K; Imaizumi T; Maeda H; Nagata H; Tsukimori K; Takeshita A; Nakano H
Venous distensibility during pregnancy. Comparisons between normal pregnancy and preeclampsia.
Hypertension 1994;24(4):461-6.
1994: Hirooka Y; Egashira K; Imaizumi T; Tagawa T; Kai H; Sugimachi M; Takeshita A
Effect of L-arginine on acetylcholine-induced endothelium-dependent vasodilation differs between the coronary and forearm vasculatures in humans.
Journal of the American College of Cardiology 1994;24(4):948-55.
1994: Muramatsu K; Numaguchi K; Egashira K; Takahashi T; Kasuya H; Takeshita A
Effects of N-nitro-L-arginine on coronary artery tone and reactive hyperemia after brief coronary occlusion in conscious dogs.
Coronary artery disease 1994;5(10):815-20.
1994: Hirooka Y; Imaizumi T; Tagawa T; Shiramoto M; Endo T; Ando S; Takeshita A
Effects of L-arginine on impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure.
Circulation 1994;90(2):658-68.
1994: Koyanagi S; Aoki M; Tashiro H; Narabayashi H; Inou T; Takeshita A; Nakamura M; Noma M; Tajimi T; Kikuchi Y
Prevalence and pathogenesis of silent myocardial ischemia following myocardial infarction.
Japanese circulation journal 1994;58(8):635-45.
1994: Tagawa T; Imaizumi T; Harada S; Endo T; Shiramoto M; Hirooka Y; Takeshita A
Nitric oxide influences neuronal activity in the nucleus tractus solitarius of rat brainstem slices.
Circulation research 1994;75(1):70-6.
1994: Takahashi T; Tomoike H; Muramatsu K; Imamura Y; Narishige T; Takeshita A; Nakamura M
Effects of a new calcium antagonist, CD-832, on coronary and systemic hemodynamics in conscious dogs.
Journal of cardiovascular pharmacology 1994;24(1):8-12.
1994: Masaki H; Imaizumi T; Harasawa Y; Takeshita A
Dynamic arterial baroreflex in rabbits with heart failure induced by rapid pacing.
The American journal of physiology 1994;267(1 Pt 2):H92-9.
1994: Egashira K; Hirooka Y; Kai H; Sugimachi M; Suzuki S; Inou T; Takeshita A
Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia.
Circulation 1994;89(6):2519-24.
1994: Akatsuka Y; Egashira K; Katsuda Y; Narishige T; Ueno H; Shimokawa H; Takeshita A
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Cardiovascular research 1994;28(6):906-11.
1994: Ando S; Imaizumi T; Harada S; Suzuki S; Sugimachi M; Sunagawa K; Hirooka Y; Takeshita A
Postganglionic sympathetic nerve discharges can contain both central and pulse-related oscillations simultaneously in rabbits.
Journal of the autonomic nervous system 1994;47(3):189-99.
1994: Harasawa Y; Imaizumi T; Ando S; Masaki H; Harada S; Momohara M; Takeshita A
Influence of arotinolol hydrochloride on heart rate spectrum in hypertensive subjects.
Japanese circulation journal 1994;58(5):326-37.
1994: Noma M; Tomoike H; Ando H; Mohri M; Takeshita A; Nakamura M
Collateral development induced by repetitive brief coronary occlusion relates to the functional state of pre-existing collaterals.
Japanese circulation journal 1994;58(4):269-77.
1994: Kai H; Koyanagi S; Hirooka Y; Sugimachi M; Sadoshima J; Suzuki S; Takeshita A
Right-to-left shunt across atrial septal defect related to tricuspid regurgitation: assessment by transesophageal Doppler echocardiography.
American heart journal 1994;127(3):578-84.
1994: Hirakawa Y; Kuga T; Kanaide H; Takeshita A
Actions of a new Ca2+ channel antagonist, CD832, on two types of Ca2+ channels in smooth muscle.
European journal of pharmacology 1994;252(3):267-74.
1994: Yoshida T; Harasawa Y; Kubota T; Chishaki H; Kubo T; Sunagawa K; Takeshita A
Role of carotid sinus baroreflex in attenuating systemic arterial pressure variability studied in anesthetized dogs.
The American journal of physiology 1994;266(2 Pt 2):H720-9.
1994: Imaizumi T; Harasawa Y; Ando S; Sugimachi M; Takeshita A
Transfer function analysis from arterial baroreceptor afferent activity to renal nerve activity in rabbits.
The American journal of physiology 1994;266(1 Pt 2):H36-42.
1994: Narishige T; Egashira K; Akatsuka Y; Imamura Y; Takahashi T; Kasuya H; Takeshita A
Glibenclamide prevents coronary vasodilation induced by beta 1-adrenoceptor stimulation in dogs.
The American journal of physiology 1994;266(1 Pt 2):H84-92.
1994: Shiramoto M; Imaizumi T; Endo T; Tagawa T; Kubo T; Tokunaga S; Ando S; Takeshita A
Effects of a novel dihydropyridine calcium antagonist on venous capacitance in Wistar-Kyoto rats.
Drugs under experimental and clinical research 1994;20(2):61-8.
1993: Tagawa H; Tomoike H; Mitsuoka W; Satoh S; Kuga T; Shimokawa H; Nakamura M; Takeshita A
Hyperreactivity of aortic smooth muscle to serotonin is related to the presence of atheroma in Watanabe heritable hyperlipidaemic rabbits.
Cardiovascular research 1993;27(12):2164-9.
1993: Fukai T; Koyanagi S; Takeshita A
Role of coronary vasospasm in the pathogenesis of myocardial infarction: study in patients with no significant coronary stenosis.
American heart journal 1993;126(6):1305-11.
1993: Ando S; Imaizumi T; Takeshita A
Effects of patterns of sympathetic nerve stimulation on vasoconstricting responses in the hindquarter of rabbits.
Journal of the autonomic nervous system 1993;45(3):225-33.
1993: Narishige T; Egashira K; Akatsuka Y; Takahashi T; Takeshita A
Effects of iomeprol, a new nonionic contrast medium, vis a vis iopamidol and nitroglycerin, on coronary diameter and blood flow in chronically instrumented dogs.
Cardiovascular and interventional radiology 1993;16(6):343-7.
1993: Suyama A C; Sunagawa K; Sugimachi M; Anan T; Egashira K; Takeshita A
Differentiation between aberrant ventricular conduction and ventricular ectopy in atrial fibrillation using RR interval scattergram.
Circulation 1993;88(5 Pt 1):2307-14.
1993: Narishige T; Egashira K; Akatsuka Y; Katsuda Y; Numaguchi K; Sakata M; Takeshita A
Glibenclamide, a putative ATP-sensitive K+ channel blocker, inhibits coronary autoregulation in anesthetized dogs.
Circulation research 1993;73(4):771-6.
1993: Hata H; Egashira K; Fukai T; Ohara Y; Kasuya H; Takahashi T; Takeshita A
The role of endothelium-derived nitric oxide in acetylcholine-induced coronary vasoconstriction in closed-chest pigs.
Coronary artery disease 1993;4(10):891-8.
1993: Hoka S; Takeshita A; Yamamoto K; Ito N
Effects of high salt intake on control of hindlimb vascular resistance by arterial baroreflex and vagal afferents in spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1993;20(10):663-9.
1993: Fukai T; Egashira K; Hata H; Numaguchi K; Ohara Y; Takahashi T; Tomoike H; Takeshita A
Serotonin-induced coronary spasm in a swine model. A minor role of defective endothelium-derived relaxing factor.
Circulation 1993;88(4 Pt 1):1922-30.
1993: Tagawa T; Imaizumi T; Endo T; Shiramoto M; Hirooka Y; Ando S; Takeshita A
Vasodilatory effect of arginine vasopressin is mediated by nitric oxide in human forearm vessels.
The Journal of clinical investigation 1993;92(3):1483-90.
1993: Kuga T; Ohara Y; Hata H; Hirakawa Y; Tomoike H; Takeshita A
Inhibitory effects of heparin, aspirin and ketanserin on coronary artery vasoconstriction after arterial balloon injury in hypercholesterolemic miniature pigs.
Journal of the American College of Cardiology 1993;22(1):291-5.
1993: Kuga T; Egashira K; Inou T; Takeshita A
Correlation of basal coronary artery tone with constrictive response to ergonovine in patients with variant angina.
Journal of the American College of Cardiology 1993;22(1):144-50.
1993: Egashira K; Inou T; Hirooka Y; Kai H; Sugimachi M; Suzuki S; Kuga T; Urabe Y; Takeshita A
Effects of age on endothelium-dependent vasodilation of resistance coronary artery by acetylcholine in humans.
Circulation 1993;88(1):77-81.
1993: Egashira K; Inou T; Hirooka Y; Yamada A; Urabe Y; Takeshita A
Evidence of impaired endothelium-dependent coronary vasodilatation in patients with angina pectoris and normal coronary angiograms.
The New England journal of medicine 1993;328(23):1659-64.
1993: Masaki H; Imaizumi T; Harada S; Momohara M; Hirooka Y; Takeshita A
Effects of a novel orally effective V1-receptor antagonist, OPC-21268, on AVP-induced sympathoinhibition.
The American journal of physiology 1993;264(6 Pt 2):R1089-94.
1993: Masaki H; Imaizumi T; Ando S; Hirooka Y; Harada S; Momohara M; Nagano M; Takeshita A
Production of chronic congestive heart failure by rapid ventricular pacing in the rabbit.
Cardiovascular research 1993;27(5):828-31.
1993: Takahashi T; Fukai T; Hata H; Kasuya H; Kuga T; Egashira K; Takeshita A
Effects of a new calcium antagonist, CD-832, on experimental coronary artery spasm in miniature pigs.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7(2):265-71.
1993: Suzuki S; Ando S; Imaizumi T; Takeshita A
Effects of anesthesia on sympathetic nerve rhythm: power spectral analysis.
Journal of the autonomic nervous system 1993;43(1):51-8.
1993: Imaizumi T; Sugimachi M; Harasawa Y; Ando S; Sunagawa K; Hirooka Y; Takeshita A
Contribution of wall mechanics to the dynamic properties of aortic baroreceptors.
The American journal of physiology 1993;264(3 Pt 2):H872-80.
1993: Harada S; Tokunaga S; Momohara M; Masaki H; Tagawa T; Imaizumi T; Takeshita A
Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits.
Circulation research 1993;72(3):511-6.
1993: Tashiro H; Shimokawa H; Koyanagi S; Takeshita A
Clinical characteristics of patients with spontaneous remission of variant angina.
Japanese circulation journal 1993;57(2):117-22.
1993: Kuga T; Tagawa H; Tomoike H; Mitsuoka W; Egashira S; Ohara Y; Takeshita A; Nakamura M
Role of coronary artery spasm in progression of organic coronary stenosis and acute myocardial infarction in a swine model. Importance of mode of onset and duration of coronary artery spasm.
Circulation 1993;87(2):573-82.
1993: Egashira K; Inou T; Hirooka Y; Yamada A; Maruoka Y; Kai H; Sugimachi M; Suzuki S; Takeshita A
Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions.
The Journal of clinical investigation 1993;91(1):29-37.
1993: Lai C P; Egashira K; Tashiro H; Narabayashi H; Koyanagi S; Imaizumi T; Takeshita A
Beneficial effects of atrial natriuretic peptide on exercise-induced myocardial ischemia in patients with stable effort angina pectoris.
Circulation 1993;87(1):144-51.
1993: Sunagawa K; Sugimachi M; Todaka K; Kobota T; Hayashida K; Itaya R; Chishaki A; Takeshita A
Optimal coupling of the left ventricle with the arterial system.
Basic research in cardiology 1993;88 Suppl 2():75-90.
1993: Sunagawa K; Sugimachi M; Kubota T; Takeshita A
[Baroreflex control of arterial blood pressure--physiological implication of cardiac and vascular blood pressure regulation]
Japanese circulation journal 1993;57 Suppl 4():1147-9.
1992: Kai H; Koyanagi S; Takeshita A
Aortic valve prolapse with aortic regurgitation assessed by Doppler color-flow echocardiography.
American heart journal 1992;124(5):1297-304.
1992: Imaizumi T; Hirooka Y; Masaki H; Harada S; Momohara M; Tagawa T; Takeshita A
Effects of L-arginine on forearm vessels and responses to acetylcholine.
Hypertension 1992;20(4):511-7.
1992: Hirooka Y; Imaizumi T; Sugimachi M; Takeshita A
Mechanisms involved in aortic baroreceptor excitation during drug-induced aortic pressure elevation in intact rabbits.
Journal of the autonomic nervous system 1992;40(2):99-106.
1992: Harada S; Imaizumi T; Ando S; Hirooka Y; Sunagawa K; Takeshita A
Arterial baroreflex dynamics in normotensive and spontaneously hypertensive rats.
The American journal of physiology 1992;263(3 Pt 2):R524-8.
1992: Hirooka Y; Imaizumi T; Masaki H; Ando S; Harada S; Momohara M; Takeshita A
Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.
Hypertension 1992;20(2):175-80.
1992: Egashira K; Tomoike H; Hayashi Y; Yamada A; Nakamura M; Takeshita A
Mechanism of ergonovine-induced hyperconstriction of the large epicardial coronary artery in conscious dogs a month after arterial injury.
Circulation research 1992;71(2):435-42.
1992: Imamura Y; Tomoike H; Narishige T; Takahashi T; Kasuya H; Takeshita A
Glibenclamide decreases basal coronary blood flow in anesthetized dogs.
The American journal of physiology 1992;263(2 Pt 2):H399-404.
1992: Kubota T; Chishaki H; Yoshida T; Sunagawa K; Takeshita A; Nose Y
How to encode arterial pressure into carotid sinus nerve to invoke natural baroreflex.
The American journal of physiology 1992;263(1 Pt 2):H307-13.
1992: Imaizumi T; Harada S; Hirooka Y; Masaki H; Momohara M; Takeshita A
Effects of OPC-21268, an orally effective vasopressin V1 receptor antagonist in humans.
Hypertension 1992;20(1):54-8.
1992: Sadoshima J; Koyanagi S; Sugimachi M; Hirooka Y; Takeshita A
Evaluation of the severity of mitral regurgitation by transesophageal Doppler flow echocardiography.
American heart journal 1992;123(5):1245-51.
1992: Kubota T; Alexander J; Itaya R; Todaka K; Sugimachi M; Sunagawa K; Nose Y; Takeshita A
Dynamic effects of carotid sinus baroreflex on ventriculoarterial coupling studied in anesthetized dogs.
Circulation research 1992;70(5):1044-53.
1992: Imaizumi T; Hirooka Y; Takeshita A
Decreased skeletal muscle vasodilation in patients with congestive heart failure.
Japanese circulation journal 1992;56(5):500-3.
1992: Ando S; Imaizumi T; Harada S; Hirooka Y; Takeshita A
Atrial natriuretic peptide increases human capillary filtration and venous distensibility.
Journal of hypertension 1992;10(5):451-7.
1992: Egashira K; Inou T; Yamada A; Hirooka Y; Takeshita A
Preserved endothelium-dependent vasodilation at the vasospastic site in patients with variant angina.
The Journal of clinical investigation 1992;89(3):1047-52.
1992: Hirooka Y; Imaizumi T; Harada S; Masaki H; Momohara M; Tagawa T; Takeshita A
Endothelium-dependent forearm vasodilation to acetylcholine but not to substance P is impaired in patients with heart failure.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S221-5.
1991: Kubota T; Itaya R; Todaka K; Sugimachi M; Sunagawa K; Takeshita A
Effects of the new cardiotonic phosphodiesterase inhibitor 1,2-dihydro-5- imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridine-carbonitrile hydrochloride monohydrate on aortic input impedance.
Arzneimittel-Forschung 1991;41(12):1211-5.
1991: Harada S; Imaizumi T; Momohara M; Masaki H; Ando S; Takeshita A
Arginine vasopressin attenuates phenylephrine-induced forearm vasoconstriction in men.
Clinical science (London, England : 1979) 1991;81(6):733-7.
1991: Egashira K; Inou T; Imaizumi T; Tomoike H; Takeshita A
Effects of synthetic human atrial natriuretic peptide on the human coronary circulation in subjects with normal coronary arteries.
Japanese circulation journal 1991;55(11):1050-6.
1991: Lai C P; Koyanagi S; Sadoshima J; Takeshita A; Tokunaga K
Transesophageal echocardiographic findings of quadricuspid aortic valve.
Japanese heart journal 1991;32(5):731-4.
1991: Harada S; Ando S; Imaizumi T; Hirooka Y; Sunagawa K; Takeshita A
Arterial baroreflex control of cardiac and renal sympathetic nerve activities is uniform in frequency domain.
The American journal of physiology 1991;261(2 Pt 2):R296-300.
1991: Kubota T; Imaizumi T; Chishaki A; Hayashi Y; Inou T; Takeshita A
Acute myocardial infarction with a hemodynamic pattern resembling constrictive pericarditis.
Japanese heart journal 1991;32(4):515-20.
1991: Takeshita A
[Vasopressin and cardiovascular control]
Fukuoka igaku zasshi = Hukuoka acta medica 1991;82(7):411-4.
1991: Hirooka Y; Ando S; Imaizumi T; Suzuki S; Takeshita A
Exogenous prostacyclin does not sensitize arterial baroreceptors.
The American journal of physiology 1991;260(6 Pt 2):H1760-6.
1991: Aoki M; Sakai K; Koyanagi S; Takeshita A; Nakamura M
Effect of nitroglycerin on coronary collateral function during exercise evaluated by quantitative analysis of thallium-201 single photon emission computed tomography.
American heart journal 1991;121(5):1361-6.
1991: Ando S; Koyanagi S; Muramatsu K; Itaya R; Takeshita A; Nakamura M
Clinical characteristics of patients with dilated cardiomyopathy and bradyarrhythmias.
Journal of cardiology 1991;21(1):53-9.
1991: Yoshida M; Imaizumi T; Ando S; Hirooka Y; Harada S; Takeshita A
Impaired forearm vasodilatation by acetylcholine in patients with hypertension.
Heart and vessels 1991;6(4):218-23.
1990: Ando H; Imaizumi T; Urabe Y; Takeshita A; Nakamura M
Apical segmental dysfunction in hypertrophic cardiomyopathy: subgroup with unique clinical features.
Journal of the American College of Cardiology 1990;16(7):1579-88.
1990: Imaizumi T; Takeshita A; Nakamura N; Sakai K; Hirooka Y; Suzuki S; Yoshida M; Nakamura M
Effects of captopril on forearm oxygen consumption during dynamic handgrip exercise in patients with congestive heart failure.
Japanese heart journal 1990;31(6):817-28.
1990: Takeshita A
[Effects of atrial natriuretic peptide on control of autonomic nervous activity]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990;35(10):1778-84.
1990: Hirooka Y; Takeshita A; Imaizumi T; Suzuki S; Yoshida M; Ando S; Nakamura M
Attenuated forearm vasodilative response to intra-arterial atrial natriuretic peptide in patients with heart failure.
Circulation 1990;82(1):147-53.
1990: Hirakawa Y; Koyanagi S; Matsumoto T; Itaya R; Takeshita A; Nakamura M
Familial dilated cardiomyopathy complicated by left ventricular aneurysm.
Japanese heart journal 1990;31(2):245-9.
1990: Sugimachi M; Imaizumi T; Sunagawa K; Hirooka Y; Todaka K; Takeshita A; Nakamura M
A new method to identify dynamic transduction properties of aortic baroreceptors.
The American journal of physiology 1990;258(3 Pt 2):H887-95.
1990: Aoki M; Koyanagi S; Sakai K; Irie T; Takeshita A; Nakamura M; Nakagaki O
Exercise-induced silent myocardial ischemia in patients with vasospastic angina.
American heart journal 1990;119(3 Pt 1):551-6.
1990: Imaizumi T; Takeshita A; Suzuki S; Yoshida M; Ando S; Nakamura M
Age-independent forearm vasodilatation by acetylcholine and adenosine 5'-triphosphate in humans.
Clinical science (London, England : 1979) 1990;78(1):89-93.
1990: Imaizumi T; Takeshita A; Yamamoto K; Nakamura M; Sueishi K
Limited maximal vasodilator capacity of forearm resistance vessels in patients with hypertrophic cardiomyopathy.
Heart and vessels 1990;5(3):159-65.
1990: Yamamoto K; Takeshita A; Ashihara T; Imaizumi T; Nakamura M
Alteration in the sarcolemmal Na(+)-K+ pump of hindquarters resistance arteries in DOCA-salt rats.
Clinical and experimental hypertension. Part A, Theory and practice 1990;12(7):1237-54.
1990: Imaizumi T; Takeshita A; Yoshida M; Suzuki S; Ando S; Hirooka Y; Nakamura M
Different effects of alpha-human atrial natriuretic peptide and nitroglycerin on cardiac dimensions in humans.
Heart and vessels 1990;5(2):87-92.
1989: Koyanagi S; Takeshita A; Nakamura M
Clinical characteristics of sudden cardiac death in patients with vasospastic angina.
Japanese circulation journal 1989;53(12):1541-5.
1989: Suzuki S; Takeshita A; Imaizumi T; Hirooka Y; Yoshida M; Ando S; Nakamura M
Central nervous system mechanisms involved in inhibition of renal sympathetic nerve activity induced by arginine vasopressin.
Circulation research 1989;65(5):1390-9.
1989: Egashira K; Araki H; Takeshita A; Nakamura M
Silent myocardial ischemia in patients with variant angina.
Japanese circulation journal 1989;53(11):1452-7.
1989: Hirakawa Y; Koyanagi S; Matsumoto T; Takeshita A; Nakamura M
A case of variant angina associated with eosinophilia.
The American journal of medicine 1989;87(4):472-4.
1989: Irie T; Imaizumi T; Matuguchi T; Koyanagi S; Kanaide H; Takeshita A; Nakamura M
Increased fibrinopeptide A during anginal attacks in patients with variant angina.
Journal of the American College of Cardiology 1989;14(3):589-94; discussion 595-6.
1989: Suzuki S; Takeshita A; Imaizumi T; Hirooka Y; Yoshida M; Ando S; Nakamura M
Biphasic forearm vascular responses to intraarterial arginine vasopressin.
The Journal of clinical investigation 1989;84(2):427-34.
1989: Kitazono T; Imaizumi T; Imayama S; Shinkai H; Takeshita A; Nakamura M
Two cases of myocardial infarction in type 4 Ehlers-Danlos syndrome.
Chest 1989;95(6):1274-7.
1989: Suzuki S; Takeshita A; Imaizumi T; Hirooka Y; Yoshida M; Nakamura M
Evidence against the central nervous system being involved in altered reflex control of sympathetic nerve activity by atrial natriuretic peptide.
Brain research 1989;485(1):109-14.
1989: Okamatsu S; Takeshita A; Nakamura M
Impaired blood pressure response to exercise in patients with coronary artery disease: possible contribution of attenuated reflex vasoconstriction in non-exercising muscles.
British heart journal 1989;61(2):149-54.
1989: Jingu S; Takeshita A; Imaizumi T; Sakai K; Nakamura M
Age-related decreases in cardiac receptor control of forearm vascular resistance in humans.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11 Suppl 1():211-6.
1988: Hirooka Y; Takeshita A; Imaizumi T; Nakamura N; Tomoike H; Nakamura M
Effects of alpha-human atrial natriuretic peptide on the interrelationship of arterial pressure, aortic nerve activity, and aortic diameter.
Circulation research 1988;63(6):987-96.
1988: Imaizumi T; Takeshita A; Nakamura N; Hirooka Y; Suzuki S; Yoshida M; Nakamura M
Vasodilating effect of the new beta-blocker tilisolol hydrochloride in humans.
Arzneimittel-Forschung 1988;38(9):1342-4.
1988: Hirooka Y; Urabe Y; Imaizumi T; Takeshita A; Tajimi T; Koyanagi S; Nakamura M
The usefulness of equilibrium radionuclide ventriculography in the diagnosis of arrhythmogenic right ventricular dysplasia and a report of cases of a familial occurrence.
Japanese circulation journal 1988;52(6):511-7.
1988: Matsuguchi T; Araki H; Nakamura N; Etoh Y; Okamatsu S; Takeshita A; Nakamura M
Prevention of vasospastic angina by alcohol ingestion: report of 2 cases.
Angiology 1988;39(4):394-400.
1988: Suzuki S; Tajimi T; Takeshita A; Nakamura M; Kinoshita K; Tokunaga K
Isolated right heart purulent pericarditis forming a large mediastinal mass.
Chest 1988;93(3):667-8.
1988: Jingu S; Takeshita A; Imaizumi T; Nakamura M; Shindo M; Tanaka H
Exercise training augments cardiopulmonary baroreflex control of forearm vascular resistance in middle-aged subjects.
Japanese circulation journal 1988;52(2):162-8.
1988: Ashihara T; Takeshita A; Imaizumi T; Yamamoto K; Hoka S; Nakamura M
Decreased hindquarters venous distensibility during high salt intake in stroke-prone spontaneously hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(1):59-78.
1988: Suzuki S; Takeshita A; Imaizumi T; Hirooka Y; Yoshida M; Nakamura M
Evidence against the central nervous system involved in altered reflex control of sympathetic nerve activity by atrial natriuretic peptide.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10 Suppl 1():263-8.
1987: Imaizumi T; Takeshita A; Nakamura M
Peripheral vascular reactivity in patients with variant angina.
Japanese circulation journal 1987;51(11):1268-72.
1987: Imaizumi T; Takeshita A; Higashi H; Nakamura M
alpha-ANP alters reflex control of lumbar and renal sympathetic nerve activity and heart rate.
The American journal of physiology 1987;253(5 Pt 2):H1136-40.
1987: Takeshita A; Imaizumi T; Nakamura N; Higashi H; Sasaki T; Nakamura M; Kangawa K; Matsuo H
Attenuation of reflex forearm vasoconstriction by alpha-human atrial natriuretic peptide in men.
Circulation research 1987;61(4):555-9.
1987: Sadoshima J; Nakashima Y; Taira Y; Koyanagi S; Takeshita A; Tanaka K; Nakamura M
A case of primary dissecting aneurysm of the coronary artery.
Japanese heart journal 1987;28(5):799-804.
1987: Sadoshima J; Taira Y; Shimokawa H; Koyanagi S; Takeshita A; Nakamura M
Two cases of dilated cardiomyopathy complicated by left ventricular aneurysm.
Chest 1987;92(2):377-9.
1984: Shimada R; Tajimi T; Koyanagi S; Orita Y; Takeshita A; Nakamura M; Hirata T
Two-dimensional echocardiographic findings in double-chambered right ventricle.
American heart journal 1984;108(4 Pt 1):1059-61.
1982: Makino N; Inou T; Tajimi T; Kikuchi Y; Takeshita A; Mitsutake A; Orita Y; Nakamura M
Multiple atherosclerotic coronary aneurysms in association with acute myocardial infarction.
Japanese heart journal 1982;23(3):375-80.
1982: Kaseda S; Koiwaya Y; Tajimi T; Mitsutake A; Kanaide H; Takeshita A; Kikuchi Y; Nakamura M; Mayumi H; Komori M; Tokunaga K
Huge false aneurysm due to rupture of the right coronary artery in Behcet's syndrome.
American heart journal 1982;103(4 Pt 1):569-71.
1981: Yamamoto K; Koiwaya Y; Tajimi T; Inou T; Mitsutake A; Orita Y; Takeshita A; Nakamura M
Coronary arterial spasm in single coronary artery.
Circulation 1981;64(6):1287-90.
1981: Mitsutake A; Nakamura M; Inou T; Kikuchi Y; Takeshita A; Fujimi S
Intense, persistent myocardial avid technetium-99m-pyrophosphate scintigraphy in acute myocarditis.
American heart journal 1981;101(5):683-4.
1981: Koiwaya Y; Nakamura M; Mitsutake A; Tanaka S; Takeshita A
Increased exercise tolerance after oral diltiazem, a calcium antagonist, in angina pectoris.
American heart journal 1981;101(2):143-9.

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