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Koji Takeuchi

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Kikuko Amagase; D Hara; T Murakami; Y Yoshida; Koji Takeuchi
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Hiroshi Satoh; Yasutada Akiba; Kikuko Amagase; Satomi Ebara; Koji Takeuchi
Cyclooxygenase (COX)-1 and COX-2 both play an important role in the protection of the duodenal mucosa in cats.
Michiyo Akagi; Kikuko Amagase; Toshiko Murakami; Koji Takeuchi
Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract.

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2013: Kikuko Amagase; D Hara; T Murakami; Y Yoshida; Koji Takeuchi
Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2013;64(1):65-75.
2013: Hiroshi Satoh; Yasutada Akiba; Kikuko Amagase; Satomi Ebara; Koji Takeuchi
Cyclooxygenase (COX)-1 and COX-2 both play an important role in the protection of the duodenal mucosa in cats.
The Journal of pharmacology and experimental therapeutics 2013;344(1):189-95.
2013: Michiyo Akagi; Kikuko Amagase; Toshiko Murakami; Koji Takeuchi
Irsogladine: overview of the mechanisms of mucosal protective and healing- promoting actions in the gastrointestinal tract.
Current pharmaceutical design 2013;19(1):106-14.
2012: Hiroshi Satoh; Kikuko Amagase; Koji Takeuchi
Exacerbation of nonsteroidal anti-inflammatory drug-induced small intestinal lesions by antisecretory drugs in rats: the role of intestinal motility.
The Journal of pharmacology and experimental therapeutics 2012;343(2):270-7.
2012: Shinichi Kato; Narumi Matsuda; Kenjiro Matsumoto; Naoki Onimaru; Kikuko Amagase; Syunji Horie; Mai Wada; Masashi Yasuda; Koji Takeuchi
Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;66(3):226-34.
2012: Koji Takeuchi; Kikuko Amagase
Evaluation of gastric ulcerogenic and healing impairment effects of bisphosphonates: adverse gastric reactions of bisphosphonate.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2012;Chapter 21():Unit 21.10.1-29.
2012: Masashi Yasuda; Daichi Utsumi; Chihiro Yabe-Nishimura; Naoki Yamanaka; Kikuko Amagase; Maho Iimori; Kazumi Iwata; Shinichi Kato; Yumeno Kitahara; Kuniharu Matsuno; Koji Takeuchi
Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(10):G1133-42.
2012: Koji Takeuchi
Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility.
World journal of gastroenterology : WJG 2012;18(18):2147-60.
2012: S Takayama; E Hashimoto; C Izuhara; S Kaneko; N Yamada; S Yamanaka; Koji Takeuchi
A new model of gastric bleeding induced in rats by aspirin plus clopidogrel under stimulation of acid secretion. Prophylactic effects of antiulcer drugs.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012;63(1):41-52.
2012: Kikuko Amagase; Naoya Kinoshita; Azusa Kojo; Ami Mizunoe; Eiji Nakamura; Akimu Ochi; Masaya Taue; Koji Takeuchi
New therapeutic strategy for amino acid medicine: prophylactic and healing promoting effect of monosodium glutamate against NSAID-induced enteropathy.
Journal of pharmacological sciences 2012;118(2):131-7.
2011: Kikuko Amagase; A Inaba; Y Ishikawa; T Murakami; K Nukui; T Senta; Koji Takeuchi
Gastric ulcerogenic and healing impairment effects of risedronate, a nitrogen-containing bisphosphonate in rats. Comparison with alendronate and minodronate.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(6):609-18.
2011: Koji Takeuchi; Akiko Tanaka; Melinda Gyenge; Azusa Kojo; Kazuo Nukui; Kikuko Amagase
Aggravation by paroxetine, a selective serotonin reuptake inhibitor, of antral lesions generated by nonsteroidal anti-inflammatory drugs in rats.
The Journal of pharmacology and experimental therapeutics 2011;338(3):850-9.
2011: Y Kawahara; N Matsuda; Y Nakase; Kikuko Amagase; Y Isomoto; Shinichi Kato; Koji Takeuchi
Role of macrophage colony-stimulating factor (M-CSF)-dependent macrophages in gastric ulcer healing in mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(4):441-8.
2011: Koji Takeuchi
[Development and repair of NSAIDs-induced small intestinal lesions: relation to COX isozymes and EP receptor subtypes].
Nihon rinsho. Japanese journal of clinical medicine 2011;69(6):1123-8.
2011: Hironori Takasuka; Shusaku Hayashi; Masafumi Koyama; Masashi Yasuda; Eitaro Aihara; Kikuko Amagase; Koji Takeuchi
Carbon monoxide involved in modulating HCO3- secretion in rat duodenum.
The Journal of pharmacology and experimental therapeutics 2011;337(1):293-300.
2011: Kikuko Amagase; Shinichi Kato; Eiji Nakamura; Koji Takeuchi
[Prophylactic effect of glutamate on gastrointestinal damage].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(12):1711-9.
2011: Koji Takeuchi; Shinichi Kato; Kikuko Amagase
Gastric ulcerogenic and healing impairment actions of alendronate, a nitrogen-containing bisphosphonate - prophylactic effects of rebamipide.
Current pharmaceutical design 2011;17(16):1602-11.
2011: F Ise; H Takasuka; S Hayashi; K Takahashi; M Koyama; E Aihara; Koji Takeuchi
Stimulation of duodenal HCO₃⁻ secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones.
Acta physiologica (Oxford, England) 2011;201(1):117-26.
2010: Koji Takeuchi; Kikuko Amagase; Naoko Abe; Azusa Kojo
[Pathogenic mechanism of aspirin-induced gastric ulceration and its characteristics].
Nihon rinsho. Japanese journal of clinical medicine 2010;68(11):1962-5.
2010: Koji Takeuchi; Hiroshi Satoh
Measurement of small intestinal damage.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2010;Chapter 21():Unit 21.7.
2010: Yoshikazu Kubo; Aiko Kumano; Kohei Kamei; Kikuko Amagase; Naoko Abe; Koji Takeuchi
Urocortin prevents indomethacin-induced small intestinal lesions in rats through activation of CRF2 receptors.
Digestive diseases and sciences 2010;55(6):1570-80.
2010: Koji Takeuchi; Mayu Tanigami; Kikuko Amagase; Akimu Ochi; Sayaka Okuda; Ryo Hatazawa
Endogenous prostaglandin E2 accelerates healing of indomethacin-induced small intestinal lesions through upregulation of vascular endothelial growth factor expression by activation of EP4 receptors.
Journal of gastroenterology and hepatology 2010;25 Suppl 1():S67-74.
2010: Kikuko Amagase; Akimu Ochi; Tetsuya Sugihara; Shinichi Kato; Koji Takeuchi
Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats.
Journal of gastroenterology and hepatology 2010;25 Suppl 1():S111-8.
2010: Koji Takeuchi; Akiko Tanaka; Shinichi Kato; Kikuko Amagase; Hiroshi Satoh
Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.
Clinica chimica acta; international journal of clinical chemistry 2010;411(7-8):459-66.
2010: Yuka Nakamori; Yoshino Komatsu; Tohru Kotani; Shinji Kojima; Koji Takeuchi
Pathogenic importance of cysteinyl leukotrienes in development of gastric lesions induced by ischemia/reperfusion in mice.
The Journal of pharmacology and experimental therapeutics 2010;333(1):91-8.
2010: Koji Takeuchi; Shinichi Kato; Kikuko Amagase
Prostaglandin EP receptors involved in modulating gastrointestinal mucosal integrity.
Journal of pharmacological sciences 2010;114(3):248-61.
2010: Koji Takeuchi
Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in the gastrointestinal tract.
Advances in clinical chemistry 2010;51():121-44.
2010: Koji Takeuchi; Masafumi Koyama; Shusaku Hayashi; Eitaro Aihara
Prostaglandin EP receptor subtypes involved in regulating HCO(3)(-) secretion from gastroduodenal mucosa.
Current pharmaceutical design 2010;16(10):1241-51.
2010: Kikuko Amagase; Eiji Nakamura; Takuya Endo; Shusaku Hayashi; Mai Hasumura; Hisayuki Uneyama; Kunio Torii; Koji Takeuchi
New frontiers in gut nutrient sensor research: prophylactic effect of glutamine against Helicobacter pylori-induced gastric diseases in Mongolian gerbils.
Journal of pharmacological sciences 2010;112(1):25-32.
2009: Shinichi Kato; F Ohkawa; Y Ito; Kikuko Amagase; Koji Takeuchi
Role of endothelial nitric oxide synthase in aggravation of indomethacin-induced gastric damage in adjuvant arthritic rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009;60(4):147-55.
2009: Yoko Sasaki; Eitaro Aihara; Yumi Ohashi; Sayaka Okuda; Hironori Takasuka; Kento Takahashi; Koji Takeuchi
Stimulation by sparkling water of gastroduodenal HCO3- secretion in rats.
Medical science monitor : international medical journal of experimental and clinical research 2009;15(12):BR349-56.
2009: Shinichi Kato; Ryoji Kawahara; Masashi Yasuda; Kikuko Amagase; Koji Takeuchi
Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats: pathogenic role of inducible and endothelial nitric oxide.
Journal of pharmacological sciences 2009;111(3):244-52.
2009: Naho Kato; Yuji Mashita; Shinichi Kato; Shoji Mitsufuji; Toshikazu Yoshikawa; Koji Takeuchi
Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/cGMP-dependent mechanism.
Digestive diseases and sciences 2009;54(11):2346-56.
2009: Y Ohashi; Eitaro Aihara; H Takasuka; K Takahashi; Koji Takeuchi
Antral ulcers induced by alendronate, a nitrogen-containing biphophonate, in rat stomachs - prophylactic effect of rebamipide.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2009;60(3):85-93.
2009: Shusaku Hayashi; Nobuaki Takahashi; Naoto Kurata; Aya Yamaguchi; Hirofumi Matsui; Shinichi Kato; Koji Takeuchi
Involvement of aquaporin-1 in gastric epithelial cell migration during wound repair.
Biochemical and biophysical research communications 2009;386(3):483-7.
2009: Tohru Kotani; Yoshino Komatsu; Yuka Nakamori; Koji Takeuchi
A novel model of ischemic enteritis induced in rats by stenosis of the superior mesenteric artery.
Life sciences 2009;84(17-18):615-21.
2009: Shun Terashima; Hikaru Nishio; Michitaka Ogura; Maya Honda; Koji Takeuchi
Involvement of prostacyclin/IP receptors in decreased acid response of damaged stomachs--mediation by somatostatin/SST2 receptors.
Life sciences 2009;84(5-6):172-80.
2008: Yasuyuki Ito; Sayaka Okuda; Fumikazu Ohkawa; Shinichi Kato; Shoji Mitsufuji; Toshikazu Yoshikawa; Koji Takeuchi
Dual role of nitric oxide in gastric hypersecretion in the distended stomach: inhibition of acid secretion and stimulation of pepsinongen secretion.
Life sciences 2008;83(25-26):886-92.
2008: S Hayashi; Eiji Nakamura; Y Kubo; N Takahashi; A Yamaguchi; H Matsui; S J Hagen; Koji Takeuchi
Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59(4):691-706.
2008: Kohei Kamei; Yoshikazu Kubo; Naho Kato; Ryo Hatazawa; Kikuko Amagase; Koji Takeuchi
Prophylactic effect of irsogladine maleate against indomethacin-induced small intestinal lesions in rats.
Digestive diseases and sciences 2008;53(10):2657-66.
2008: Kazutomo Kita; Kento Takahashi; Yumi Ohashi; Hironori Takasuka; Eitaro Aihara; Koji Takeuchi
Phosphodiesterase isozymes involved in regulation of formula secretion in isolated mouse stomach in vitro.
The Journal of pharmacology and experimental therapeutics 2008;326(3):889-96.
2008: Yoko Aoi; Shun Terashima; M Ogura; Hikaru Nishio; Shinichi Kato; Koji Takeuchi
Roles of nitric oxide (NO) and NO synthases in healing of dextran sulfate sodium-induced rat colitis.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59(2):315-36.
2007: Masaki Taniguchi; Y Mashita; Y Matsuzaka; Shinichi Kato; Koji Takeuchi
Role of capsaicin-sensitive afferent neurons in receptive relaxation induced by gastric distension in rats.
Inflammopharmacology 2007;15(6):273-7.
2007: Hikaru Nishio; Yujiro Hayashi; Shun Terashima; Koji Takeuchi
Protective effect of pranlukast, a cysteinyl-leukotriene receptor 1 antagonist, on indomethacin-induced small intestinal damage in rats.
Inflammopharmacology 2007;15(6):266-72.
2007: Msamune Hayashi; Kazutomo Kita; Yumi Ohashi; Eitaro Aihara; Koji Takeuchi
Phosphodiesterase isozymes involved in regulation of HCO3- secretion in isolated mouse duodenum in vitro.
Biochemical pharmacology 2007;74(10):1507-13.
2007: Yoko Sasaki; Eitaro Aihara; Fumitaka Ise; Kazutomo Kita; Koji Takeuchi
Stimulatory effect of Coca-Cola on gastroduodenal HCO3- secretion in rats.
Inflammopharmacology 2007;15(5):223-8.
2007: S Hayashi; Eiji Nakamura; T Endo; Y Kubo; Koji Takeuchi
Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
Inflammopharmacology 2007;15(5):218-22.
2007: Ryo Hatazawa; Mayu Tanigami; N Izumi; K Kamei; Akiko Tanaka; Koji Takeuchi
Prostaglandin E2 stimulates VEGF expression in primary rat gastric fibroblasts through EP4 receptors.
Inflammopharmacology 2007;15(5):214-7.
2007: K Nishikawa; Kikuko Amagase; Koji Takeuchi
Effect of dopamine on the healing of acetic acid-induced gastric ulcers in rats.
Inflammopharmacology 2007;15(5):209-13.
2007: Tohru Kotani; Akari Nakagiri; Y Murashima; Koji Takeuchi
Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.
Inflammopharmacology 2007;15(5):203-8.
2007: Eitaro Aihara; S Hayashi; Kikuko Amagase; Shinichi Kato; Koji Takeuchi
Prophylactic effect of rebamipide against the irritative and healing impairment actions of alendronate in rat stomachs.
Inflammopharmacology 2007;15(5):196-202.
2007: Ryo Hatazawa; Akiko Tanaka; Mayu Tanigami; Kikuko Amagase; Shinichi Kato; Yasuko Ashida; Koji Takeuchi
Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(4):G788-97.
2007: Shinichi Kato; Yasuyuki Ito; Hikaru Nishio; Yoko Aoi; Kikuko Amagase; Koji Takeuchi
Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis: involvement of enhanced expression of TLR4.
Life sciences 2007;81(16):1309-16.
2007: Hikaru Nishio; Shun Terashima; Masato Nakashima; Eitaro Aihara; Koji Takeuchi
Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2007;58(3):407-21.
2007: Koji Takeuchi; Akiko Tanaka; Shinichi Kato; Eitaro Aihara; Kikuko Amagase
Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)benzamido)ethyl) benzoic acid (CJ-42794), a selective antagonist of prostaglandin E receptor subtype 4, on ulcerogenic and healing responses in rat gastrointestinal mucosa.
The Journal of pharmacology and experimental therapeutics 2007;322(3):903-12.
2007: Mitsuaki Okayama; Shusaku Hayashi; Yoko Aoi; Hikaru Nishio; Shinichi Kato; Koji Takeuchi
Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats.
Digestive diseases and sciences 2007;52(9):2095-103.
2007: Kikuko Amagase; Shusaku Hayashi; Kaoru Nishikawa; Eitaro Aihara; Koji Takeuchi
Impairment of gastric ulcer healing by alendronate, a nitrogen-containing bisphosphonate, in rats.
Digestive diseases and sciences 2007;52(8):1879-89.
2007: Eitaro Aihara; Yoko Nomura; Yoko Sasaki; Fumitaka Ise; Kazutomo Kita; Koji Takeuchi
Involvement of prostaglandin E receptor EP3 subtype in duodenal bicarbonate secretion in rats.
Life sciences 2007;80(26):2446-53.
2007: Aya Yokota; Masaki Taniguchi; Yuka Takahira; Akiko Tanaka; Koji Takeuchi
Dexamethasone damages the rat stomach but not small intestine during inhibition of COX-1.
Digestive diseases and sciences 2007;52(6):1452-61.
2007: Tohru Kotani; Yukiko Murashima; Atsushi Kobata; Kikuko Amagase; Koji Takeuchi
Pathogenic importance of pepsin in ischemia/reperfusion-induced gastric injury.
Life sciences 2007;80(21):1984-92.
2007: Akiko Tanaka; Ryo Hatazawa; Yuka Takahira; Nahoko Izumi; Ludmila Filaretova; Koji Takeuchi
Preconditioning stress prevents cold restraint stress-induced gastric lesions in rats: roles of COX-1, COX-2, and PLA2.
Digestive diseases and sciences 2007;52(2):478-87.
2007: Koji Takeuchi; Ryo Hatazawa; Mayu Tanigami; Akiko Tanaka; Ryoko Ohno; Aya Yokota
Role of endogenous nitric oxide (NO) and NO synthases in healing of indomethacin-induced intestinal ulcers in rats.
Life sciences 2007;80(4):329-36.
2007: Atsushi Kobata; Tohru Kotani; Yoshino Komatsu; Kikuko Amagase; Shinichi Kato; Koji Takeuchi
Dual action of nitric oxide in the pathogenesis of ischemia/reperfusion-induced mucosal injury in mouse stomach.
Digestion 2007;75(4):188-97.
2007: Shinichi Kato; Hikaru Nishio; Michitaka Ogura; Koji Takeuchi
Tacrolimus (FK506), an immunosuppressive agent, prevents indomethacin-induced small intestinal ulceration in the rat: inhibition of inducible nitric oxide synthase expression.
Journal of pharmacological sciences 2007;103(1):40-7.
2006: Koji Takeuchi; Eitaro Aihara; Yoko Sasaki; Yoko Nomura; Fumitaka Ise
Involvement of cyclooxygenase-1, prostaglandin E2 and EP1 receptors in acid-induced HCO3- secretion in stomach.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2006;57(4):661-76.
2006: Hikaru Nishio; Yujiro Hayashi; Shun Terashima; Koji Takeuchi
Role of endogenous nitric oxide in mucosal defense of inflamed rat stomach following iodoacetamide treatment.
Life sciences 2006;79(16):1523-30.
2006: Eitaro Aihara; Yoko Sasaki; Fumitaka Ise; Kazutomo Kita; Yoko Nomura; Koji Takeuchi
Distinct mechanisms of acid-induced HCO3- secretion in normal and slightly permeable stomachs.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G464-71.
2006: Yusuke Sugiyama; Shinichi Kato; Shoji Mitsufuji; Takeshi Okanoue; Koji Takeuchi
Pathogenic role of endothelial nitric oxide synthase (eNOS/NOS-III) in cerulein-induced rat acute pancreatitis.
Digestive diseases and sciences 2006;51(8):1396-403.
2006: Ryo Hatazawa; Ryoko Ohno; Mayu Tanigami; Akiko Tanaka; Koji Takeuchi
Roles of endogenous prostaglandins and cyclooxygenase isozymes in healing of indomethacin-induced small intestinal lesions in rats.
The Journal of pharmacology and experimental therapeutics 2006;318(2):691-9.
2006: Koji Takeuchi; Aya Yokota; Akiko Tanaka; Yuka Takahira
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Digestive diseases and sciences 2006;51(7):1250-9.
2006: Kazuhiro Fukushima; Yoko Aoi; Shinichi Kato; Koji Takeuchi
Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.
World journal of gastroenterology : WJG 2006;12(19):3031-7.
2006: Kenji Nagahama; Masanori Yamato; Hikaru Nishio; Koji Takeuchi
Essential role of pepsin in pathogenesis of acid reflux esophagitis in rats.
Digestive diseases and sciences 2006;51(2):303-9.
2006: Akari Nakagiri; Kazuhiro Fukushima; Shinichi Kato; Koji Takeuchi
Less irritative action of wine and Japanese sake in rat stomachs: a comparative study with ethanol.
Digestive diseases and sciences 2006;51(2):289-97.
2006: Tohru Kotani; Atsushi Kobata; Eiji Nakamura; Kikuko Amagase; Koji Takeuchi
Roles of cyclooxygenase-2 and prostacyclin/IP receptors in mucosal defense against ischemia/reperfusion injury in mouse stomach.
The Journal of pharmacology and experimental therapeutics 2006;316(2):547-55.
2006: Ryoichi Tsubouchi; Shusaku Hayashi; Yoko Aoi; Hikaru Nishio; Shun Terashima; Shinichi Kato; Koji Takeuchi
Healing impairment effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats.
Digestion 2006;74(2):91-100.
2006: Yuji Mashita; Masaki Taniguchi; Aya Yokota; Akiko Tanaka; Koji Takeuchi
Oral but not parenteral aspirin upregulates COX-2 expression in rat stomachs. a relationship between COX-2 expression and PG deficiency.
Digestion 2006;73(2-3):124-32.
2006: Eitaro Aihara; Masamune Hayashi; Yoko Nomura; Shinichi Kato; Koji Takeuchi
Stimulation by bradykinin of HCO3- secretion in rat gastroduodenal mucosa.
Medical science monitor : international medical journal of experimental and clinical research 2006;12(1):BR1-7.
2005: Eitaro Aihara; Masamune Hayashi; Yoko Sasaki; Atsushi Kobata; Koji Takeuchi
Mechanisms underlying capsaicin-stimulated secretion in the stomach: comparison with mucosal acidification.
The Journal of pharmacology and experimental therapeutics 2005;315(1):423-32.
2005: Eitaro Aihara; Shigeru Kagawa; Masamune Hayashi; Koji Takeuchi
ACE inhibitor and AT1 antagonist stimulate duodenal HCO3- secretion mediated by a common pathway - involvement of PG, NO and bradykinin.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2005;56(3):391-406.
2005: Koji Takeuchi; Eitaro Aihara; Masamune Hayashi; Yoko Sasaki
Role of prostaglandin E receptor subtypes in gastroduodenal HCO3- secretion.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(4):395-403.
2005: Shinichi Kato; Eitaro Aihara; Katsuhide Yoshii; Koji Takeuchi
Dual action of prostaglandin E2 on gastric acid secretion through different EP-receptor subtypes in the rat.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(1):G64-9.
2005: Aya Yokota; Masaki Taniguchi; Yuka Takahira; Akiko Tanaka; Koji Takeuchi
Rofecoxib produces intestinal but not gastric damage in the presence of a low dose of indomethacin in rats.
The Journal of pharmacology and experimental therapeutics 2005;314(1):302-9.
2005: Yusuke Sugiyama; Shinichi Kato; Mitsumasa Abe; Shoji Mitsufuji; Koji Takeuchi
Different effects of dexamethasone and the nitric oxide synthase inhibitor L-NAME on caerulein-induced rat acute pancreatitis, depending on the severity.
Inflammopharmacology 2005;13(1-3):291-301.
2005: Akari Nakagiri; Shinichi Kato; Koji Takeuchi
Irritative action of alcoholic beverages in rat stomachs: a comparative study with ethanol.
Inflammopharmacology 2005;13(1-3):273-9.
2005: Tohru Kotani; Toshio Fujimura; Kikuko Amagase; Susumu Okabe; Koji Takeuchi
A novel gastric lesion model induced in rats by partial gastric vascular ligation.
Inflammopharmacology 2005;13(1-3):261-72.
2005: Aya Yokota; Masaki Taniguchi; Akiko Tanaka; Koji Takeuchi
Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib.
Inflammopharmacology 2005;13(1-3):209-16.
2005: Eitaro Aihara; Masamune Hayashi; Yoko Sasaki; Koji Takeuchi
Gastric HCO3- secretion induced by mucosal acidification: different mechanisms depending on acid concentration.
Inflammopharmacology 2005;13(1-3):179-90.
2005: Masanori Yamato; Kenji Nagahama; Tohru Kotani; Shinichi Kato; Koji Takeuchi
Biphasic effect of prostaglandin E2 in a rat model of esophagitis mediated by EP1 receptors: relation to pepsin secretion.
Digestion 2005;72(2-3):109-18.
2005: Koji Takeuchi; Akiko Tanaka; Yujiro Hayashi; Aya Yokota
COX inhibition and NSAID-induced gastric damage--roles in various pathogenic events.
Current topics in medicinal chemistry 2005;5(5):475-86.
2005: Akiko Tanaka; Masahiro Matsumoto; Yujiro Hayashi; Koji Takeuchi
Functional mechanism underlying cyclooxygenase-2 expression in rat small intestine following administration of indomethacin: relation to intestinal hypermotility.
Journal of gastroenterology and hepatology 2005;20(1):38-45.
2004: György Rumi; Ryoichi Tsubouchi; Hikaru Nishio; Shinichi Kato; Gyula Mózsik; Koji Takeuchi
Dual role of endogenous nitric oxide in development of dextran sodium sulfate-induced colitis in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2004;55(4):823-36.
2004: Mitsuaki Okayama; Ryoichi Tsubouchi; Shinichi Kato; Koji Takeuchi
Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats.
Digestive diseases and sciences 2004;49(10):1696-704.
2004: György Rumi; Ryoichi Tsubouchi; Mitsuaki Okayama; Shinichi Kato; Gyula Mózsik; Koji Takeuchi
Protective effect of lactulose on dextran sulfate sodium-induced colonic inflammation in rats.
Digestive diseases and sciences 2004;49(9):1466-72.
2004: Ryoko Ohno; Aya Yokota; Akiko Tanaka; Koji Takeuchi
Induction of small intestinal damage in rats following combined treatment with cyclooxygenase-2 and nitric-oxide synthase inhibitors.
The Journal of pharmacology and experimental therapeutics 2004;310(2):821-7.
2004: Masako Aoi; Eitaro Aihara; Masato Nakashima; Koji Takeuchi
Participation of prostaglandin E receptor EP4 subtype in duodenal bicarbonate secretion in rats.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G96-103.
2004: Kenji Kanatsu; Eitaro Aihara; Mitsuaki Okayama; Shinichi Kato; Koji Takeuchi
Mucosal irritative and healing impairment action of risedronate in rat stomachs: comparison with alendronate.
Journal of gastroenterology and hepatology 2004;19(5):512-20.
2004: Mitsumasa Abe; Shinichi Kato; Mitsuaki Okayama; Eitaro Aihara; Shoji Mitsufuji; Koji Takeuchi
Prophylactic effect of restraint stress on cerulein-induced pancreatitis in rats: role of endogenous glucocorticoids.
Digestive diseases and sciences 2004;49(3):521-8.
2004: Masanori Takeeda; Yujiro Hayashi; Masanori Yamato; M Murakami; Koji Takeuchi
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2004;55(1 Pt 2):193-205.
2004: Koji Takeuchi; Akiko Tanaka; Yujiro Hayashi; Yoshiaki Kubo
Functional mechanism underlying COX-2 expression following administration of indomethacin in rat stomachs: importance of gastric hypermotility.
Digestive diseases and sciences 2004;49(2):180-7.
2004: Mitsuaki Okayama; Ryoichi Tsubouchi; Hikaru Nishio; Shinichi Kato; Koji Takeuchi
Protective effect of intra-rectal administration of rebamipide on dextran sulfate sodium-induced rat colitis.
Digestion 2004;70(4):240-9.
2004: Masato Nakashima; Masako Aoi; Eitaro Aihara; Koji Takeuchi
No role for prostacyclin IP receptors in duodenal HCO3- secretion induced by mucosal acidification in mice--comparison with capsaicin-induced response.
Digestion 2004;70(1):16-25.
2003: Shoko Hase; Aya Yokota; Akari Nakagiri; Koji Takeuchi
Prostaglandin E2 aggravates gastric mucosal injury induced by histamine in rats through EP1 receptors.
Life sciences 2003;74(5):629-41.
2003: Koji Takeuchi; Akiko Tanaka; R Ohno; A Yokota
Role of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2003;54 Suppl 4():165-82.
2003: Masanori Takeeda; Masanori Yamato; Shinichi Kato; Koji Takeuchi
Cyclooxygenase isozymes involved in adaptive functional responses in rat stomach after barrier disruption.
The Journal of pharmacology and experimental therapeutics 2003;307(2):713-9.
2003: Shinichi Kato; Eitaro Aihara; Akio Nakamura; Hong Xin; Hirofumi Matsui; Kazuhiro Kohama; Koji Takeuchi
Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protection.
Biochemical pharmacology 2003;66(6):1115-21.
2003: Shigeru Kagawa; Masako Aoi; Yoshiaki Kubo; Tohru Kotani; Koji Takeuchi
Stimulation by capsaicin of duodenal HCO3(-) secretion via afferent neurons and vanilloid receptors in rats: comparison with acid-induced HCO3(-) response.
Digestive diseases and sciences 2003;48(9):1850-6.
2003: Kenji Nagahama; Masanori Yamato; Shinichi Kato; Koji Takeuchi
Protective effect of lafutidine, a novel H2-receptor antagonist, on reflux esophagitis in rats through capsaicin-sensitive afferent neurons.
Journal of pharmacological sciences 2003;93(1):55-61.
2003: Koji Takeuchi; Shinichi Kato; Masanori Takeeda; Yoshihiro Ogawa; Masato Nakashima; Masahiro Matsumoto
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.
The Journal of pharmacology and experimental therapeutics 2003;304(3):1055-62.
2003: Tohru Miyazawa; Masao Matsumoto; Shinichi Kato; Koji Takeuchi
Dopamine-induced protection against indomethacin-evoked intestinal lesions in rats--role of anti-intestinal motility mediated by D2 receptors.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(2):BR71-7.
2003: Koji Takeuchi; Tohru Miyazawa; Masahiro Matsumoto; Yujiro Hayashi
Both selective COX-1 and COX-2 inhibitors aggravate gastric damage induced in rats by 2-deoxy-D-glucose. relation to gastric hypermotility and COX-2 expression.
Digestion 2003;68(2-3):71-9.
2003: Yusaku Komoike; Masato Nakashima; Akari Nakagiri; Koji Takeuchi
Prostaglandin E receptor EP1 subtype but not prostacyclin IP receptor involved in mucosal blood flow response of mouse stomachs following barrier disruption.
Digestion 2003;67(4):186-94.
2002: Hiroshi Mimaki; Shigeru Kagawa; Masako Aoi; Shinichi Kato; Tsutumi Satoshi; Kazuhiro Kohama; Koji Takeuchi
Effect of lafutidine, a histamine H2-receptor antagonist, on gastric mucosal blood flow and duodenal HCO3- secretion in rats: relation to capsaicin-sensitive afferent neurons.
Digestive diseases and sciences 2002;47(12):2696-703.
2002: Akiko Tanaka; Shoko Hase; Tohru Miyazawa; Ryoko Ohno; Koji Takeuchi
Role of cyclooxygenase (COX)-1 and COX-2 inhibition in nonsteroidal anti-inflammatory drug-induced intestinal damage in rats: relation to various pathogenic events.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1248-54.
2002: Shinichi Kato; Yoshihiro Ogawa; Kenji Kanatsu; Mitsuaki Okayama; Toshio Watanabe; Tetsuo Arakawa; Koji Takeuchi
Ulcerogenic influence of selective cyclooxygenase-2 inhibitors in the rat stomach with adjuvant-induced arthritis.
The Journal of pharmacology and experimental therapeutics 2002;303(2):503-9.
2002: Ludmila Filaretova; Akiko Tanaka; Tohru Miyazawa; Shinichi Kato; Koji Takeuchi
Mechanisms by which endogenous glucocorticoid protects against indomethacin-induced gastric injury in rats.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(5):G1082-9.
2002: Koji Takeuchi; Shigeru Kagawa; Hiroshi Mimaki; Masako Aoi; Shoji Kawauchi
COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats.
Digestive diseases and sciences 2002;47(9):2116-24.
2002: Yoshihiro Ogawa; Kenji Kanatsu; Taeko Iino; Shinichi Kato; Y I Jeong; N Shibata; K Takada; Koji Takeuchi
Protection against dextran sulfate sodium-induced colitis by microspheres of ellagic acid in rats.
Life sciences 2002;71(7):827-39.
2002: Koji Takeuchi; Akiko Tanaka; Tohru Miyazawa
[Pathogenesis of NSAID-induced gastric mucosal damage--search for primary events and role of COX inhibition].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2002;99(7):751-9.
2002: Yusaku Komoike; Masanori Takeeda; Akiko Tanaka; Shinichi Kato; Koji Takeuchi
Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid.
Digestive diseases and sciences 2002;47(7):1538-45.
2002: Shinichi Kato; Koji Takeuchi
Alteration of gastric ulcerogenic and healing responses in rats with adjuvant-induced arthritis.
Japanese journal of pharmacology 2002;89(1):1-6.
2002: Kimihito Tashima; Masato Nakashima; Shigeru Kagawa; Shinichi Kato; Koji Takeuchi
Gastric hyperemic response induced by acid back-diffusion in rat stomachs following barrier disruption -- relation to vanilloid type-1 receptors.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(5):BR157-63.
2002: Tomonori Kunikata; Akiko Tanaka; Tohru Miyazawa; Shinichi Kato; Koji Takeuchi
16,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors.
Digestive diseases and sciences 2002;47(4):894-904.
2002: Akiko Tanaka; Hideo Araki; S Hase; Y Komoike; Koji Takeuchi
Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury.
Alimentary pharmacology & therapeutics 2002;16 Suppl 2():90-101.
2002: Koji Takeuchi; Yoshihiro Ogawa; Shigeru Kagawa; H Ukawa
Gastric ulcerogenic responses following barrier disruption in knockout mice lacking prostaglandin EP1 receptors.
Alimentary pharmacology & therapeutics 2002;16 Suppl 2():74-82.
2002: Shinichi Kato; Masakazu Umeda; Masanori Takeeda; Kenji Kanatsu; Koji Takeuchi
Effect of taurine on ulcerogenic response and impaired ulcer healing induced by monochloramine in rat stomachs.
Alimentary pharmacology & therapeutics 2002;16 Suppl 2():35-43.
2002: Akiko Tanaka; Shoko Hase; Tohru Miyazawa; Koji Takeuchi
Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage.
The Journal of pharmacology and experimental therapeutics 2002;300(3):754-61.
2002: Koji Takeuchi; Shoko Hase
[Proton pump inhibitors: Pantoprazole].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 2():655-60.
2002: Taeko Iino; Kimihito Tashima; Masakazu Umeda; Yoshihiro Ogawa; Masanori Takeeda; Kanji Takata; Koji Takeuchi
Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion.
Life sciences 2002;70(10):1139-50.
2002: Hideo Araki; Yusaku Komoike; Masahiro Matsumoto; Akiko Tanaka; Koji Takeuchi
Healing of duodenal ulcers is not impaired by indomethacin or rofecoxib, the selective COX-2 inhibitor, in rats.
Digestion 2002;66(3):145-53.
2002: Koji Takeuchi; Tohu Miyazawa; Akiko Tanaka; Shinichi Kato; Tomonori Kunikata
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.
Digestion 2002;66(1):30-41.
2002: Tomonori Kunikata; Tohru Miyazawa; Kenji Kanatsu; Shinichi Kato; Koji Takeuchi
Protective effect of thiaton, an antispasmodic drug, against indomethacin-induced intestinal damage in rats.
Japanese journal of pharmacology 2002;88(1):45-54.
2001: H Mizoguchi; Yoshihiro Ogawa; Kenji Kanatsu; Akiko Tanaka; Shinichi Kato; Koji Takeuchi
Protective effect of rebamipide on indomethacin-induced intestinal damage in rats.
Journal of gastroenterology and hepatology 2001;16(10):1112-9.
2001: Akiko Tanaka; H Mizoguchi; Shoko Hase; Tohru Miyazawa; Koji Takeuchi
Intestinal protection by lafutidine, a histamine H(2)-receptor antagonist, against indomethacin-induced damage in rats--role of endogenous nitric oxide.
Medical science monitor : international medical journal of experimental and clinical research 2001;7(5):869-77.
2001: Koji Takeuchi; H Mizoguchi; Hideo Araki; Yusaku Komoike; Kazuo Suzuki
Lack of gastric toxicity of nitric oxide-releasing indomethacin, NCX-530, in experimental animals.
Digestive diseases and sciences 2001;46(8):1805-18.
2001: Shinichi Kato; Kazuo Suzuki; H Ukawa; Yusaku Komoike; Koji Takeuchi
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis.
Digestive diseases and sciences 2001;46(8):1690-9.
2001: S Sugamoto; S Kawauch; O Furukawa; T H Mimaki; Koji Takeuchi
Role of endogenous nitric oxide and prostaglandin in duodenal bicarbonate response induced by mucosal acidification in rats.
Digestive diseases and sciences 2001;46(6):1208-16.
2001: Koji Takeuchi; Hideo Araki; Masakazu Umeda; Yusaku Komoike; Kazuo Suzuki
Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice.
The Journal of pharmacology and experimental therapeutics 2001;297(3):1160-5.
2001: Koji Takeuchi; Shinichi Kato; Akiko Tanaka
[Gastrointestinal cytoprotection by prostaglandin E and EP receptor subtypes].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2001;117(4):274-82.
2001: Shinichi Kato; Hideo Araki; Shoji Kawauchi; Koji Takeuchi
Body temperature dependency in baclofen-induced gastric acid secretion in rats relation to capsaicin-sensitive afferent neurons.
Life sciences 2001;68(17):1951-63.
2001: Koji Takeuchi; Kazuo Suzuki; H Mizoguchi; Hideo Araki; H Nishiwaki
Monochloramine impairs mucosal blood flow response and healing of gastric lesions in rats: relation to capsaicin-sensitive sensory neurons.
Journal of gastroenterology and hepatology 2001;16(3):282-9.
2001: Shoji Kawauchi; S Sugamoto; O Furukawa; H Mimaki; Koji Takeuchi
Stimulation by nitric oxide of gastric acid secretion in bullfrog fundic mucosa in vitro.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2001;52(1):93-105.
2001: Koji Takeuchi; Akiko Tanaka
[Gastrointestinal sparing anti-inflammatory drugs--COX-2 selective inhibitors and NO-releasing NSAIDs].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 2001;117(2):138-48.
2001: H Mizoguchi; Shoko Hase; Akiko Tanaka; Koji Takeuchi
Lack of small intestinal ulcerogenecity of nitric oxide-releasing indomethacin, NCX-530, in rats.
Alimentary pharmacology & therapeutics 2001;15(2):257-67.
2001: Taeko Iino; K Nakahara; W Miki; Y Kiso; Yoshihiro Ogawa; Shinichi Kato; Koji Takeuchi
Less damaging effect of whisky in rat stomachs in comparison with pure ethanol. Role of ellagic acid, the nonalcoholic component.
Digestion 2001;64(4):214-21.
2001: Hiroshi Mimaki; Shoji Kawauchi; Shigeru Kagawa; S Ueki; Koji Takeuchi
Bicarbonate stimulatory action of nizatidine, a histamine H(2)-receptor antagonist, in rat duodenums.
Journal of physiology, Paris 2001;95(1-6):165-71.
2001: Tomonori Kunikata; Hideo Araki; Masanori Takeeda; Shinichi Kato; Koji Takeuchi
Prostaglandin E prevents indomethacin-induced gastric and intestinal damage through different EP receptor subtypes.
Journal of physiology, Paris 2001;95(1-6):157-63.
2001: Koji Takeuchi; Shinichi Kato; Yoshihiro Ogawa; Kenji Kanatsu; Masakazu Umeda
Role of endogenous prostacyclin in gastric ulcerogenic and healing responses--a study using IP-receptor knockout mice.
Journal of physiology, Paris 2001;95(1-6):75-80.
2001: Koji Takeuchi; Shoko Hase; H Mizoguchi; Yusaku Komoike; Akiko Tanaka
Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid.
Journal of physiology, Paris 2001;95(1-6):51-7.
2001: Akiko Tanaka; H Mizoguchi; Tomonori Kunikata; Tohru Miyazawa; Koji Takeuchi
Protection by constitutively formed nitric oxide of intestinal damage induced by indomethacin in rats.
Journal of physiology, Paris 2001;95(1-6):35-41.
2001: Akiko Tanaka; Hideo Araki; Yusaku Komoike; Shoko Hase; Koji Takeuchi
Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs.
Journal of physiology, Paris 2001;95(1-6):21-7.
2001: Shinichi Kato; Yoshihiro Ogawa; Akiko Tanaka; Tomonori Kunikata; Koji Takeuchi
Delayed healing of gastric ulcers in adjuvant arthritis rats: role of acid secretion and basic fibroblast growth factor.
Digestion 2001;63(3):171-9.
2001: Kazuo Suzuki; Hideo Araki; H Mizoguchi; O Furukawa; Koji Takeuchi
Prostaglandin E inhibits indomethacin-induced gastric lesions through EP-1 receptors.
Digestion 2001;63(2):92-101.
2001: Shinichi Kato; Akiko Tanaka; Yoshihiro Ogawa; Kenji Kanatsu; K Seto; T Yoneda; Koji Takeuchi
Effect of polaprezinc on impaired healing of chronic gastric ulcers in adjuvant-induced arthritic rats--role of insulin-like growth factors (IGF)-1.
Medical science monitor : international medical journal of experimental and clinical research 2001;7(1):20-5.
2000: A Fujita; Kimihito Tashima; M Nishijima; Koji Takeuchi
Enhancement of peptone-induced gastric acid secretion in streptozotocin-induced diabetic rats.
Japanese journal of pharmacology 2000;84(4):405-11.
2000: K Suzuki; Hideo Araki; Y Komoike; Koji Takeuchi
Permissive role of neutrophils in pathogenesis of indomethacin-induced gastric lesions in rats.
Medical science monitor : international medical journal of experimental and clinical research 2000;6(5):908-14.
2000: Kimihito Tashima; A Fujita; Koji Takeuchi
Aggravation of ischemia/reperfusion-induced gastric lesions in streptozotocin-diabetic rats.
Life sciences 2000;67(14):1707-18.
2000: Kimihito Tashima; A Fujita; Masakazu Umeda; Koji Takeuchi
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
Life sciences 2000;67(13):1639-52.
2000: Kimihito Tashima; M Nishijima; A Fujita; M Kubomi; Koji Takeuchi
Acid secretory changes in streptozotocin-diabetic rats: different responses to various secretagogues.
Digestive diseases and sciences 2000;45(7):1352-8.
2000: Roman P Korolkiewicz; A Fujita; K Seto; Kazuo Suzuki; Koji Takeuchi
Polaprezinc exerts a salutary effect on impaired healing of acute gastric lesions in diabetic rats.
Digestive diseases and sciences 2000;45(6):1200-9.
2000: O Furukawa; Shoji Kawauchi; H Mimaki; Koji Takeuchi
Stimulation by nitric oxide of HCO3- secretion in bullfrog duodenum in vitro--roles of cyclooxygenase-1 and prostaglandins.
Medical science monitor : international medical journal of experimental and clinical research 2000;6(3):454-9.
2000: Koji Takeuchi; Haruhiko Toyohara; Morihiko Sakaguchi
A hyperosmotic stress-induced mRNA of carp cell encodes Na(+)- and Cl(-)-dependent high affinity taurine transporter.
Biochimica et biophysica acta 2000;1464(2):219-30.
2000: Koji Takeuchi; S Sugamoto; H Yamamoto; Shoji Kawauchi; Kimihito Tashima
Interactive roles of endogenous prostaglandin and nitric oxide in regulation of acid secretion by damaged rat stomachs.
Alimentary pharmacology & therapeutics 2000;14 Suppl 1():125-34.
2000: Hideo Araki; H Ukawa; Y Sugawa; K Yagi; Kazuo Suzuki; Koji Takeuchi
The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach.
Alimentary pharmacology & therapeutics 2000;14 Suppl 1():116-24.
2000: Shinichi Kato; Akiko Tanaka; Tomonori Kunikata; H Mizoguchi; Koji Takeuchi
The roles of nitric oxide and prostaglandins in alterations of ulcerogenic and healing responses in adjuvant-induced arthritic rat stomachs.
Alimentary pharmacology & therapeutics 2000;14 Suppl 1():18-25.
2000: Koji Takeuchi; Hideo Araki; Shoji Kawauchi; Tomonori Kunikata; H Mizoguchi; Kimihito Tashima
Regulatory mechanism of acid secretion in the damaged stomach: role of endogenous nitric oxide.
Journal of gastroenterology and hepatology 2000;15 Suppl():D37-45.
2000: Roman P Korolkiewicz; Kimihito Tashima; A Fujita; Shinichi Kato; Koji Takeuchi
Exogenous insulin-like growth factor (IGF)-1 improves the impaired healing of gastric mucosal lesions in diabetic rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 2000;41(2):221-9.
2000: O Furukawa; E Kume; S Sugamoto; Shoji Kawauchi; Koji Takeuchi
Effect of ecabet disodium, a novel locally-acting antiulcer drug, on epithelial restitution following injury by hypertonic NaCl in bullfrog stomach in vitro.
Digestion 2000;62(2-3):116-25.
2000: Kimihito Tashima; M Nishijima; A Fujita; Shoji Kawauchi; Koji Takeuchi
Gastric acid secretion in streptozotocin-diabetic rats--different responses to various secretagogues.
Journal of physiology, Paris 2000;94(1):11-7.
2000: Shinichi Kato; Akiko Tanaka; Tomonori Kunikata; Masakazu Umeda; Koji Takeuchi
Protective effect of lafutidine against indomethacin-induced intestinal ulceration in rats: relation to capsaicin-sensitive sensory neurons.
Digestion 2000;61(1):39-46.
1999: A Konaka; Shinichi Kato; Akiko Tanaka; Tomonori Kunikata; Roman P Korolkiewicz; Koji Takeuchi
Roles of enterobacteria, nitric oxide and neutrophil in pathogenesis of indomethacin-induced small intestinal lesions in rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 1999;40(6):517-24.
1999: Koji Takeuchi; Kazuo Suzuki; Hideo Araki; H Mizoguchi; S Sugamoto; M Umdeda
Roles of endogenous prostaglandins and nitric oxide in gastroduodenal ulcerogenic responses induced in rats by hypothermic stress.
Journal of physiology, Paris 1999;93(5):423-31.
1999: H Yamamoto; Akiko Tanaka; Tomonori Kunikata; T Hirata; Shinichi Kato; Koji Takeuchi
Inducible types of cyclooxygenase and nitric oxide synthase in adaptive cytoprotection in rat stomachs.
Journal of physiology, Paris 1999;93(5):405-12.
1999: Roman P Korolkiewicz; Kimihito Tashima; M Kubomi; Shinichi Kato; Koji Takeuchi
Increased susceptibility of diabetic rat gastric mucosa to food deprivation during cold stress.
Digestion 1999;60(6):528-37.
1999: Koji Takeuchi; H Ukawa; Shinichi Kato; O Furukawa; Hideo Araki; Y Sugimoto; A Ichikawa; F Ushikubi; S Narumiya
Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3).
Gastroenterology 1999;117(5):1128-35.
1999: M Kitamura; S Sugamoto; Shoji Kawauchi; Shinichi Kato; Koji Takeuchi
Modulation by endogenous nitric oxide of acid secretion induced by gastric distention in rats: enhancement by nitric oxide synthase inhibitor.
The Journal of pharmacology and experimental therapeutics 1999;291(1):181-7.
1999: Koji Takeuchi; S Sugamoto; Kazuo Suzuki; Shoji Kawauchi; O Furukawa
Effects of endothelin-1 on duodenal bicarbonate secretion and mucosal integrity in rats.
The Chinese journal of physiology 1999;42(3):129-35.
1999: Akiko Tanaka; Tomonori Kunikata; H Mizoguchi; Shinichi Kato; Koji Takeuchi
Dual action of nitric oxide in pathogenesis of indomethacin-induced small intestinal ulceration in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1999;50(3):405-17.
1999: Masakazu Umeda; A Fujita; H Nishiwaki; Koji Takeuchi
Effect of lafutidine, a novel histamine H2-receptor antagonist, on monochloramine-induced gastric lesions in rats: role of capsaicin-sensitive sensory neurons.
Journal of gastroenterology and hepatology 1999;14(9):859-65.
1999: O Furukawa; M Kitamura; S Sugamoto; Koji Takeuchi
Stimulatory effect of nitric oxide on bicarbonate secretion in bullfrog duodenums in vitro.
Digestion 1999;60(4):324-31.
1999: H Nishiwaki; Shinichi Kato; S Sugamoto; Masakazu Umeda; H Morita; T Yoneta; Koji Takeuchi
Ulcerogenic and healing impairing actions of monochloramine in rat stomachs: effects of zinc L-carnosine, polaprezinc.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1999;50(2):183-95.
1999: Koji Takeuchi; H Ukawa; O Furukawa; Shoji Kawauchi; Hideo Araki; Y Sugimoto; A Ishikawa; F Ushikubi; S Narumiya
Prostaglandin E receptor subtypes involved in stimulation of gastroduodenal bicarbonate secretion in rats and mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1999;50(2):155-67.
1999: Shinichi Kato; Akiko Tanaka; Tomonori Kunikata; M Nishijima; Koji Takeuchi
Changes in gastric mucosal ulcerogenic responses in rats with adjuvant arthritis: role of nitric oxide.
Alimentary pharmacology & therapeutics 1999;13(6):833-40.
1999: A Konaka; M Nishijima; Akiko Tanaka; Tomonori Kunikata; Shinichi Kato; Koji Takeuchi
Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1999;50(1):25-38.
1999: Koji Takeuchi; A Konaka; M Nishijima; Shinichi Kato; T Yasuhiro
Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole.
Journal of gastroenterology and hepatology 1999;14(3):251-7.
1999: Koji Takeuchi; Shinichi Kato; A Konaka; Y Sugawa
Luminal calcium in regulation of nitric oxide release and acid secretion in rat stomachs after damage.
Digestive diseases and sciences 1999;44(3):515-22.
1999: H Nishiwaki; M Umeda; Hideo Araki; A Fujita; O Furukawa; Koji Takeuchi
Effect of monochloramine on recovery of gastric mucosal integrity and blood flow response in rat stomachs--relations to capsaicin-sensitive sensory neurons.
Life sciences 1999;65(11):1207-16.
1999: Koji Takeuchi; T Hirata; H Yamamoto; Tomonori Kunikata; M Ishikawa; Y Ishihara
Effects of S-0509, a novel CCKB/gastrin receptor antagonist, on acid secretion and experimental duodenal ulcers in rats.
Alimentary pharmacology & therapeutics 1999;13(1):87-96.
1998: Koji Takeuchi; Kazuo Suzuki; H Yamamoto; Hideo Araki; H Mizoguchi; H Ukawa
Cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs and gastric mucosal responses.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1998;49(4):501-13.
1998: Koji Takeuchi; K Yagi; S Sugamoto; O Furukawa; Shoji Kawauchi
Involvement of PACAP in acid-induced HCO3- response in rat duodenums.
Pharmacological research : the official journal of the Italian Pharmacological Society 1998;38(6):475-80.
1998: T Yasuhiro; A Konaka; Shinichi Kato; Koji Takeuchi
Gastric mucosal damage induced by compound 48/80: roles of serotonin and nitric oxide.
Journal of gastroenterology and hepatology 1998;13(11):1099-106.
1998: H Ukawa; H Yamakuni; Shinichi Kato; Koji Takeuchi
Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal antiinflammatory drugs on mucosal ulcerogenic and healing responses of the stomach.
Digestive diseases and sciences 1998;43(9):2003-11.
1998: Kimihito Tashima; Roman P Korolkiewicz; M Kubomi; Koji Takeuchi
Increased susceptibility of gastric mucosa to ulcerogenic stimulation in diabetic rats--role of capsaicin-sensitive sensory neurons.
British journal of pharmacology 1998;124(7):1395-402.
1998: Roman P Korolkiewicz; Piotr Rekowski; Agnieszka Szyk; Shinichi Kato; T Yasuhiro; M Kubomi; Kimihito Tashima; Koji Takeuchi
Effects of diabetes mellitus on the contractile activity of carbachol and galanin in isolated gastric fundus strips of rats.
Pharmacology 1998;57(2):65-78.
1998: Koji Takeuchi; T Yasuhiro; Y Asada; Y Sugawa
Role of nitric oxide in pathogenesis of aspirin-induced gastric mucosal damage in rats.
Digestion 1998;59(4):298-307.
1998: Koji Takeuchi; H Ukawa; A Konaka; M Kitamura; Y Sugawa
Effect of nitric oxide-releasing aspirin derivative on gastric functional and ulcerogenic responses in rats: comparison with plain aspirin.
The Journal of pharmacology and experimental therapeutics 1998;286(1):115-21.
1998: Koji Takeuchi; K Yagi; M Kitamura; M Kubomi
Stimulation of duodenal bicarbonate secretion by carbenoxolone in rats: a comparative study with prostaglandin E2.
General pharmacology 1998;30(5):739-44.
1998: Shinichi Kato; Roman P Korolkiewicz; Piotr Rekowski; Agnieszka Szyk; Y Sugawa; Koji Takeuchi
Inhibition of gastric acid secretion by galanin in rats. Relation to endogenous histamine release.
Regulatory peptides 1998;74(1):53-9.
1998: Shinichi Kato; M Kitamura; Roman P Korolkiewicz; Koji Takeuchi
Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitor.
British journal of pharmacology 1998;123(5):839-46.
1998: K Yagi; K Takehara; M Kitamura; Koji Takeuchi
Effects of pituitary adenylate cyclase activating polypeptide-27 on alkaline secretory and mucosal ulcerogenic responses in rat duodenum.
Life sciences 1998;63(5):317-25.
1997: Koji Takeuchi; K Yagi; Shinichi Kato; H Ukawa
Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats.
Gastroenterology 1997;113(5):1553-9.
1997: H Nishiwaki; Shinichi Kato; Koji Takeuchi
Irritant action of monochloramine in rat stomachs: effects of zinc L-carnosine (polaprezinc).
General pharmacology 1997;29(5):713-8.
1997: T Yasuhiro; Roman P Korolkiewicz; Shinichi Kato; Koji Takeuchi
Role of nitric oxide in pathogenesis of serotonine-induced gastric lesions in rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 1997;36(4):333-8.
1997: Shinichi Kato; H Nishiwaki; A Konaka; Koji Takeuchi
Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate.
Digestive diseases and sciences 1997;42(10):2156-63.
1997: T Hirata; H Ukawa; H Yamakuni; Shinichi Kato; Koji Takeuchi
Cyclo-oxygenase isozymes in mucosal ulcergenic and functional responses following barrier disruption in rat stomachs.
British journal of pharmacology 1997;122(3):447-54.
1997: Shinichi Kato; T Hirata; M Kitamura; Koji Takeuchi
Gastric hyperemic response during vagally mediated acid secretion by TRH analog in rats.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1351-7.
1997: Koji Takeuchi; T Hirata; Roman P Korolkiewicz; Y Sugawa; M Kubomi
Impaired duodenal bicarbonate secretion in diabetic rats. Salutary effect of nitric oxide synthase inhibitor.
Journal of physiology, Paris 1997;91(3-5):235-40.
1997: Koji Takeuchi; K Yagi; M Kitamura; H Kobayashi
Stimulatory effect of PACAP on gastroduodenal bicarbonate secretion in rats.
Journal of physiology, Paris 1997;91(3-5):229-34.
1997: T Yasuhiro; A Konaka; H Ukawa; Shinichi Kato; Koji Takeuchi
Role of nitric oxide in pathogenesis of gastric mucosal damage induced by compound 48/80 in rats.
Journal of physiology, Paris 1997;91(3-5):131-8.
1997: Koji Takeuchi; Shinichi Kato; H Nishiwaki; T Hirata
Analysis of pathogenic elements involved in gastric lesions induced by non-steroidal anti-inflammatory drugs in rats.
Journal of gastroenterology and hepatology 1997;12(5):360-7.
1997: Shinichi Kato; T Hirata; Koji Takeuchi
Nitric oxide, prostaglandin, and sensory neurons in gastric mucosal blood flow response during acid secretion in rats.
General pharmacology 1997;28(4):513-9.
1997: Koji Takeuchi; K Takehara; K Tajima; Shinichi Kato; T Hirata
Impaired healing of gastric lesions in streptozotocin-induced diabetic rats: effect of basic fibroblast growth factor.
The Journal of pharmacology and experimental therapeutics 1997;281(1):200-7.
1997: Koji Takeuchi; K Takehara; Shinichi Kato; K Yagi
PACAPs stimulate duodenal bicarbonate secretion at PACAP receptors in the rat.
The American journal of physiology 1997;272(3 Pt 1):G646-53.
1997: Koji Takeuchi; Shinichi Kato; T Yasuhiro; K Yagi
Mechanism of acid secretory changes in rat stomach after damage by taurocholate: role of nitric oxide, histamine, and sensory neurons.
Digestive diseases and sciences 1997;42(3):645-53.
1997: Koji Takeuchi; Shinichi Kato; T Hirata; H Nishiwaki
Gastric motility and mucosal ulcerogenic responses induced by prokinetic drugs in rats under prostaglandin-deficient conditions.
Digestive diseases and sciences 1997;42(2):251-8.
1997: K Takehara; Kimihito Tashima; Koji Takeuchi
Alterations in duodenal bicarbonate secretion and mucosal susceptibility to acid in diabetic rats.
Gastroenterology 1997;112(2):418-28.
1997: Shinichi Kato; Y Abe; M Konishi; N Kuroda; Koji Takeuchi
Mechanism of gastric hyperemic response during acid secretion in rats: relation to nitric oxide, prostaglandins, and sensory neurons.
Journal of clinical gastroenterology 1997;25 Suppl 1():S48-55.
1997: Koji Takeuchi; Shinichi Kato; Y Abe; M Kinoshita; M Tsuchimoto
Nitric oxide, histamine, and sensory nerves in the acid secretory response in rat stomach after damage.
Journal of clinical gastroenterology 1997;25 Suppl 1():S39-47.
1997: T Hirata; H Ukawa; M Kitamura; Koji Takeuchi
Effects of selective cyclooxygenase-2 inhibitors on alkaline secretory and mucosal ulcerogenic responses in rat duodenum.
Life sciences 1997;61(16):1603-11.
1997: K Takehara; Kimihito Tashima; Shinichi Kato; Koji Takeuchi
Failure of the nitric oxide synthase inhibitor to stimulate duodenal bicarbonate secretion in streptozotocin-diabetic rats.
Life sciences 1997;60(17):1505-14.
1997: Koji Takeuchi; Shinichi Kato; K Takehara; Y Asada; T Yasuiro
Role of nitric oxide in mucosal blood flow response and the healing of HCl-induced lesions in the rat stomach.
Digestion 1997;58(1):19-27.
1996: Koji Takeuchi; K Takehara; S Kato; Y Asada; T Yasuhiro
Changes in gastric HCO-3 secretory response to NG-nitro-L-arginine methyl ester in rats following repeated administration.
Journal of gastroenterology and hepatology 1996;11(12):1164-70.
1996: Koji Takeuchi
[Gastroduodenal bicarbonate secretion: pharmacological modulation and contribution to mucosal protection].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1996;108(6):281-93.
1996: Koji Takeuchi; T Yasuhiro; Y Asada; S Kato; Y Ishihara
Stimulation of acid secretion in rat stomach following exposure to taurocholate in the presence of the nitric oxide synthase inhibitor.
General pharmacology 1996;27(5):849-54.
1996: S Kato; S Okabe; Koji Takeuchi
Pathways mediating pentagastrin-induced mucosal blood flow response in rat stomachs.
Digestive diseases and sciences 1996;41(3):485-91.
1996: H Miyake; N Inaba; S Kato; Koji Takeuchi
Increased susceptibility of rat gastric mucosa to ulcerogenic stimulation with aging. Role of capsaicin-sensitive sensory neurons.
Digestive diseases and sciences 1996;41(2):339-45.
1995: M Hashimoto; Masayuki Imamura; Yutaka Shimada; Y Shirakata; Koji Takeuchi
Twenty-four hour monitoring of pH in the gastric tube replacing the resected esophagus.
Journal of the American College of Surgeons 1995;180(6):666-72.
1995: Koji Takeuchi; Susumu Okabe
Mechanism of gastric alkaline response in the stomach after damage. Roles of nitric oxide and prostaglandins.
Digestive diseases and sciences 1995;40(4):865-71.
1995: M Narita; S Takahashi; Koji Takeuchi; Susumu Okabe
Desensitization of capsaicin-sensitive sensory neurons in rat stomachs on chronic treatment with sodium taurocholate.
Japanese journal of pharmacology 1995;67(4):321-8.
1995: Koji Takeuchi; T Ohuchi; Susumu Okabe
Effects of nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on duodenal alkaline secretory and ulcerogenic responses induced by mepirizole in rats.
Digestive diseases and sciences 1995;40(3):670-7.
1995: Koji Takeuchi; T Ohuchi; H Harada; Susumu Okabe
Irritant and protective action of urea-urease ammonia in rat gastric mucosa. Different effects of ammonia and ammonium ion.
Digestive diseases and sciences 1995;40(2):274-81.
1995: M Tachibana; Koji Takeuchi; Susumu Okabe
Role of the sympathetic nervous system in gastric functional changes induced by thyrotropin-releasing hormone in rats.
Japanese journal of pharmacology 1995;67(2):157-64.
1995: Koji Takeuchi; K Takehara; S Kato
Effect of NG-nitro-L-arginine methyl ester, the nitric oxide synthase inhibitor, on duodenal alkaline secretion and mepirizole-induced duodenal lesions in rats.
Journal of clinical gastroenterology 1995;21 Suppl 1():S66-72.
1995: Koji Takeuchi; H Miyake
Mucosal ulceration in isolated amphibian stomachs in vitro. Roles of nutrient HC03- and endogenous prostaglandins.
Digestion 1995;56(5):357-63.
1995: Koji Takeuchi; K Takehara; T Kaneko; Susumu Okabe
Nitric oxide and prostaglandins in regulation of acid secretory response in rat stomach following injury.
The Journal of pharmacology and experimental therapeutics 1995;272(1):357-63.
1994: Koji Takeuchi; T Ohuchi; Susumu Okabe
Capsaicin-sensitive sensory neurons in healing gastric lesions induced by HCl in rats.
Digestive diseases and sciences 1994;39(12):2543-6.
1994: Koji Takeuchi; H Niida; T Ohuchi; Susumu Okabe
Influences of urethane anesthesia on indomethacin-induced gastric mucosal lesions in rats. Relation to blood glucose levels.
Digestive diseases and sciences 1994;39(12):2536-42.
1994: Koji Takeuchi; K Takehara; Susumu Okabe
Mechanisms underlying stimulation of gastroduodenal HCO3- secretion by NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthase, in rats.
Japanese journal of pharmacology 1994;66(3):295-302.
1994: K Ueshima; Koji Takeuchi; T Ohuchi; Susumu Okabe
Acid secretory and duodenal ulcerogenic responses induced by mepirizole in anesthetized rats. Relation to body temperature.
Digestive diseases and sciences 1994;39(8):1625-32.
1994: Koji Takeuchi; K Ueshima; T Ohuchi; Susumu Okabe
The role of capsaicin-sensitive sensory neurons in healing of HCl-induced gastric mucosal lesions in rats.
Gastroenterology 1994;106(6):1524-32.
1994: Koji Takeuchi; K Ueshima; T Ohuchi; Susumu Okabe
Induction of gastric lesions and hypoglycemic response by food deprivation in streptozotocin-diabetic rats.
Digestive diseases and sciences 1994;39(3):626-34.
1994: Koji Takeuchi; T Ohuchi; Susumu Okabe
Endogenous nitric oxide in gastric alkaline response in the rat stomach after damage.
Gastroenterology 1994;106(2):367-74.
1994: Koji Takeuchi; T Ohuchi; M Tachibana; Susumu Okabe
The mechanism underlying stimulation of gastric HCO3- secretion by the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester in rats.
Journal of gastroenterology and hepatology 1994;9 Suppl 1():S50-4.
1993: Koji Takeuchi; T Ohuchi; M Narita; Susumu Okabe
Capsaicin-sensitive sensory nerves in recovery of gastric mucosal integrity after damage by sodium taurocholate in rats.
Japanese journal of pharmacology 1993;63(4):479-85.
1993: Koji Takeuchi; T Ohuchi; H Miyake; Susumu Okabe
Stimulation by nitric oxide synthase inhibitors of gastric and duodenal HCO3- secretion in rats.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1512-9.
1993: S Kato; Koji Takeuchi; Susumu Okabe
Mechanism by which histamine increases gastric mucosal blood flow in the rat. Role of luminal H+.
Digestive diseases and sciences 1993;38(7):1224-32.
1993: Koji Takeuchi; T Ohuchi; H Miyake; S Niki; Susumu Okabe
Effects of nitric oxide synthase inhibitors on duodenal alkaline secretion in anesthetized rats.
European journal of pharmacology 1993;231(1):135-8.
1993: Koji Takeuchi; T Ohuchi; S Kato; Susumu Okabe
Cytoprotective action of L-arginine against HCl-induced gastric injury in rats: involvement of nitric oxide?
Japanese journal of pharmacology 1993;61(1):13-21.
1993: Koji Takeuchi; M Okada; K Ueshima; T Ohuchi; Susumu Okabe
Endogenous sulfhydryls in healing gastric mucosal injury induced by HCl in the rat.
Digestion 1993;54(2):91-7.
1993: Koji Takeuchi; T Ohuchi; J Matsumoto; Susumu Okabe
Regulation of gastroduodenal bicarbonate secretion by capsaicin-sensitive sensory neurons in rats.
Journal of clinical gastroenterology 1993;17 Suppl 1():S33-9.
1992: Koji Takeuchi; T Ohuchi; H Miyake; H Sugawara; Susumu Okabe
Effects of nitric oxide synthase inhibitors on gastric alkaline secretion in rats.
Japanese journal of pharmacology 1992;60(3):303-5.
1992: J Matsumoto; Koji Takeuchi; K Ueshima; Susumu Okabe
Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants.
Digestive diseases and sciences 1992;37(9):1336-44.
1992: J Matsumoto; K Ueshima; T Ohuchi; Koji Takeuchi; Susumu Okabe
Induction of gastric lesions by 2-deoxy-D-glucose in rats following chemical ablation of capsaicin-sensitive sensory neurons.
Japanese journal of pharmacology 1992;60(1):43-9.
1992: Koji Takeuchi; K Tachibana; K Ueshima; J Matsumoto; Susumu Okabe
Stimulation by capsaicin of gastric alkaline secretion in anesthetized rats.
Japanese journal of pharmacology 1992;59(2):151-7.
1992: Koji Takeuchi; K Ueshima; J Matsumoto; Susumu Okabe
Role of capsaicin-sensitive sensory nerves in acid-induced bicarbonate secretion in rat stomach.
Digestive diseases and sciences 1992;37(5):737-43.
1992: K Ueshima; Koji Takeuchi; Susumu Okabe
Effects of sulfhydryl-related compounds on indomethacin-induced gastric lesions in rats: role of endogenous sulfhydryls in the pathogenesis.
Japanese journal of pharmacology 1992;58(2):157-65.
1992: Koji Takeuchi; H Niida
Determination of gastroduodenal alkaline responses using pH deflection in the rat.
Journal of clinical gastroenterology 1992;14 Suppl 1():S107-13.
1992: Koji Takeuchi; J Matsumoto; K Ueshima; T Ohuchi; Susumu Okabe
Induction of duodenal ulcers in sensory deafferented rats following histamine infusion.
Digestion 1992;51(4):203-10.
1991: Koji Takeuchi; H Niida; K Ueshima; Susumu Okabe
Effect of YM-14673, an analogue of thyrotropin-releasing hormone, on duodenal bicarbonate secretion in the rat.
Archives internationales de pharmacodynamie et de thérapie 1991;314():133-46.
1991: Koji Takeuchi; H Nishiwaki; H Niida; K Ueshima; Susumu Okabe
Duodenal ulcers induced by diethyldithiocarbamate, a superoxide dismutase inhibitor, in the rat: role of antioxidative system in the pathogenesis.
Japanese journal of pharmacology 1991;57(3):299-310.
1991: Koji Takeuchi; J Matsumoto; K Ueshima; Susumu Okabe
Role of capsaicin-sensitive afferent neurons in alkaline secretory response to luminal acid in the rat duodenum.
Gastroenterology 1991;101(4):954-61.
1991: J Matsumoto; Koji Takeuchi; Susumu Okabe
Characterization of gastric mucosal blood flow response induced by intragastric capsaicin in rats.
Japanese journal of pharmacology 1991;57(2):205-13.
1991: Koji Takeuchi; M Okada; H Niida; Susumu Okabe
Dual effects of N-ethylmaleimide on ethanol-induced gastric lesions in rats.
Digestive diseases and sciences 1991;36(7):870-9.
1991: H Niida; Koji Takeuchi; Susumu Okabe
Role of thyrotropin-releasing hormone in acid secretory response induced by lowering of body temperature in the rat.
European journal of pharmacology 1991;198(2-3):137-42.
1991: H Hirose; Koji Takeuchi; Susumu Okabe
Effect of indomethacin on gastric mucosal blood flow around acetic acid-induced gastric ulcers in rats.
Gastroenterology 1991;100(5 Pt 1):1259-65.
1991: H Niida; Koji Takeuchi; K Ueshima; Susumu Okabe
Vagally mediated acid hypersecretion and lesion formation in anesthetized rat under hypothermic conditions.
Digestive diseases and sciences 1991;36(4):441-8.
1991: Koji Takeuchi; K Ueshima; Susumu Okabe
Stimulation of gastric bicarbonate secretion by an analog of thyrotropin-releasing hormone, YM-14673, in the rat.
The Journal of pharmacology and experimental therapeutics 1991;256(3):1057-62.
1991: J Matsumoto; K Ueshima; Koji Takeuchi; Susumu Okabe
Capsaicin-sensitive afferent neurons in adaptive responses of the rat stomach induced by a mild irritant.
Japanese journal of pharmacology 1991;55(1):181-5.
1991: Koji Takeuchi; K Ueshima; Y Hironaka; Y Fujioka; J Matsumoto; Susumu Okabe
Oxygen free radicals and lipid peroxidation in the pathogenesis of gastric mucosal lesions induced by indomethacin in rats. Relation to gastric hypermotility.
Digestion 1991;49(3):175-84.
1991: Koji Takeuchi; H Niida; J Matsumoto; K Ueshima; Susumu Okabe
Gastric motility changes in capsaicin-induced cytoprotection in the rat stomach.
Japanese journal of pharmacology 1991;55(1):147-55.
1990: Koji Takeuchi; H Niida; K Ueshima; Susumu Okabe
Determination of gastroduodenal alkaline responses in the rat.
Journal of pharmacological methods 1990;24(3):189-202.
1990: Koji Takeuchi; T Tanaka; S Wakabayashi; S Mochizuki; A Tomiyama; Susumu Okabe
Effects of topical application of KT1-32 on transmucosal potential difference and acid secretion in the rat stomach.
Japanese journal of pharmacology 1990;54(2):227-35.
1990: Koji Takeuchi; M Okada; H Niida; Susumu Okabe
Possible mechanisms involved in gastric hypermotility caused by indomethacin in the rat. Role of glycoprivic response.
Digestive diseases and sciences 1990;35(8):984-92.
1990: Koji Takeuchi; H Niida; Susumu Okabe
Characterization of alkaline response induced by cholinergic agents in the rat duodenum: involvement of M2 receptors and the calcium-dependent process.
The Journal of pharmacology and experimental therapeutics 1990;254(2):465-70.
1990: Koji Takeuchi; H Niida; Y Takinami; Susumu Okabe
Stimulation by prostaglandin E2 of alkaline secretion in the rat duodenum: comparative study with hypertonic NaCl.
Japanese journal of pharmacology 1990;53(1):67-74.
1990: Koji Takeuchi; H Nishiwaki; H Niida; Susumu Okabe
Body temperature-dependent action of baclofen in rat stomach. Relation to acid secretion and ulcerogenicity.
Digestive diseases and sciences 1990;35(4):458-66.
1990: Koji Takeuchi; O Furukawa; M Okada; H Niida; Susumu Okabe
Influences of stress on gastric alkaline secretion in rats.
The Journal of pharmacology and experimental therapeutics 1990;252(3):1228-33.
1990: Koji Takeuchi; H Nishiwaki; H Niida; Susumu Okabe
Different effects of cytoprotective drugs on ethanol- and aspirin-induced gastric mucosal injury in pylorus-ligated rats.
Digestive diseases and sciences 1990;35(2):178-85.
1990: Koji Takeuchi
[Bicarbonate secretion in the mucosal defensive mechanism of the duodenum. Acid neutralization with HCO3- in the lumen and mucus gel].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1990;110(2):85-104.
1990: Koji Takeuchi; H Niida; M Minami; Susumu Okabe
Determination of bicarbonate output using pH deflection in the rat duodenum: influences of prostaglandins and cholinergic agents.
Japanese journal of pharmacology 1990;52(2):225-32.
1990: H Tanaka; Koji Takeuchi; Susumu Okabe
Role of accumulated gastric content in the pathogenesis of cysteamine- and mepirizole-induced duodenal ulcers in the rat.
Journal of internal medicine. Supplement 1990;732():69-75.
1990: Koji Takeuchi; M Okada; S Ebara; H Osano
Increased microvascular permeability and lesion formation during gastric hypermotility caused by indomethacin and 2-deoxy-D-glucose in the rat.
Journal of clinical gastroenterology 1990;12 Suppl 1():S76-84.
1990: Susumu Okabe; Koji Takeuchi; H Niida; Y Takinami
Effects of TY-10957, a stable PGI2 derivative, on gastroduodenal lesions and secretory responses in the rat.
Digestion 1990;45(2):61-71.
1989: H Tanaka; Koji Takeuchi; Susumu Okabe; M Murakami
Pathogenesis of the earliest epithelial cell damage induced by mepirizole and cysteamine in the rat duodenum.
Japanese journal of pharmacology 1989;51(4):509-19.
1989: H Tanaka; Koji Takeuchi; Susumu Okabe
The relationship of intraduodenal pH and delayed gastric emptying in duodenal ulceration induced by mepirizole or cysteamine in rats.
Japanese journal of pharmacology 1989;51(4):483-92.
1989: H Tanaka; Koji Takeuchi; Susumu Okabe
Histamine-induced villous damage in the rat duodenum.
Japanese journal of pharmacology 1989;51(2):291-7.
1989: Koji Takeuchi; H Nishiwaki; M Okada; H Niida; Susumu Okabe
Bilateral adrenalectomy worsens gastric mucosal lesions induced by indomethacin in the rat. Role of enhanced gastric motility.
Gastroenterology 1989;97(2):284-93.
1989: M Okada; H Niida; Koji Takeuchi; Susumu Okabe
Role of prostaglandin deficiency in pathogenetic mechanism of gastric lesions induced by indomethacin in rats.
Digestive diseases and sciences 1989;34(5):694-702.
1989: Susumu Okabe; Koji Takeuchi; M Okada; Y Kumadaki; M Nakata; H Nakata
[Effects of nizatidine, a new histamine H2-receptor antagonist, on gastric acid secretion and various gastric and duodenal lesions in rats: comparison with cimetidine].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1989;93(3):133-44.
1989: Koji Takeuchi; M Okada; H Niida; Susumu Okabe
Role of sulfhydryls in mucosal injury caused by ethanol: relation to microvascular permeability, gastric motility and cytoprotection.
The Journal of pharmacology and experimental therapeutics 1989;248(2):836-41.
1989: H Nishiwaki; Koji Takeuchi; M Okada; H Tanaka; Susumu Okabe
Stimulation of gastric alkaline secretion by histamine in rats: possible involvement of histamine H2-receptors and endogenous prostaglandins.
The Journal of pharmacology and experimental therapeutics 1989;248(2):793-8.
1989: H Tanaka; M Nakagawa; Koji Takeuchi; Susumu Okabe
Effects of mepirizole and basic antiinflammatory drugs on HCl-ethanol-induced gastric lesions in rats.
Digestive diseases and sciences 1989;34(2):238-45.
1989: J Y Wang; S Yamasaki; Koji Takeuchi; Susumu Okabe
Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin.
Gastroenterology 1989;96(2 Pt 1):393-402.
1989: Koji Takeuchi; Y Ishihara; M Okada; H Niida; Susumu Okabe
A continuous monitoring of mucosal integrity and secretory activity in rat stomach: a preparation using a lucite chamber.
Japanese journal of pharmacology 1989;49(2):235-44.
1989: Koji Takeuchi; M Okada; H Niida; Susumu Okabe
Healing process of duodenal ulcers induced by indomethacin plus histamine in rats.
Digestion 1989;42(4):202-11.
1989: H Nishiwaki; M Okada; N Hara; Koji Takeuchi; Susumu Okabe
Mechanisms involved in aggravation of ethanol-induced gastric mucosal lesions in adrenalectomized rats.
Japanese journal of pharmacology 1989;49(1):27-35.
1989: H Tanaka; Koji Takeuchi; Susumu Okabe
Effects of the duodenal ulcerogens, mepirizole and cysteamine, on gastric motility and emptying in rats.
Scandinavian journal of gastroenterology. Supplement 1989;162():104-7.
1989: H Niida; M Okada; Koji Takeuchi; Susumu Okabe
A new model of duodenal ulcers induced in rats by diethyldithiocarbamate, a superoxide dismutase inhibitor.
Scandinavian journal of gastroenterology. Supplement 1989;162():116-9.
1989: K Kumada; K Morikawa; K Furuke; Fuminori Moriyasu; Arimichi Takabayashi; Koji Takeuchi; T Kawasaki; K Fukui; M Yamaguchi; S Matsuda
Closure of portosystemic shunt.
Journal of gastroenterology and hepatology 1989;4 Suppl 1():239-41.
1988: Koji Takeuchi; H Nishiwaki; N Hara; Susumu Okabe
Effects of gastric distension and prostaglandin on acid ethanol-induced mucosal lesions in the rat.
Digestive diseases and sciences 1988;33(12):1569-77.
1988: Koji Takeuchi; H Nishiwaki; Susumu Okabe
Effects of dopamine on gastric mucosal lesions induced by ethanol in rats. Possible involvement of antigastric motor activity mediated with alpha 2-adrenoceptors.
Digestive diseases and sciences 1988;33(12):1560-8.
1988: Koji Takeuchi; Y Nobuhara; H Tanaka; H Nishiwaki; Susumu Okabe
Effects of hemorrhagic shock on alkaline secretion and mucosal tolerance to acid in rat duodenum. A comparative study with indomethacin.
Digestive diseases and sciences 1988;33(11):1409-17.
1988: Koji Takeuchi; H Nishiwaki; Susumu Okabe
Effects of topical application of acidified omeprazole on acid secretion and transmucosal potential difference in anesthetized rat stomachs.
Japanese journal of pharmacology 1988;47(4):397-408.
1988: O Furukawa; Koji Takeuchi; H Nishiwaki; Susumu Okabe
Pathogenesis of digitoxin-induced duodenal ulcers in pregnant rats. Roles of gastric acid and duodenal alkaline secretion.
Digestive diseases and sciences 1988;33(7):889-96.
1988: J Y Wang; Koji Takeuchi; Susumu Okabe
Dissolution of antisecretory and cytoprotective action of PGE2 in rats.
Japanese journal of pharmacology 1988;47(1):103-5.
1988: Koji Takeuchi; H Nishiwaki; M Okada; Susumu Okabe
Mucosal protective action of histamine against gastric lesions induced by HCl in rats: importance of antigastric motor activity mediated by H2-receptors.
The Journal of pharmacology and experimental therapeutics 1988;245(2):632-8.
1988: S Ueki; Koji Takeuchi; Susumu Okabe
Gastric motility is an important factor in the pathogenesis of indomethacin-induced gastric mucosal lesions in rats.
Digestive diseases and sciences 1988;33(2):209-16.
1988: Koji Takeuchi; H Nishiwaki; H Osano; S Ebara; Susumu Okabe
Repair of mucosal damage induced by ethanol in the rat stomach. Effects of concentration, exposure period and prostaglandins.
Digestion 1988;40(1):1-10.
1988: Koji Takeuchi; O Furukawa; M Okada; Susumu Okabe
Duodenal ulcers induced by indomethacin plus histamine in the dog. Involvement of the impaired duodenal alkaline secretion in their pathogenesis.
Digestion 1988;39(4):230-40.
1987: Koji Takeuchi; O Furukawa; H Nishiwaki; Susumu Okabe
16,16-Dimethyl prostaglandin E2 aggravates gastric mucosal injury induced by histamine in rats. Possible role of the increased mucosal vascular permeability.
Gastroenterology 1987;93(6):1276-86.
1987: T Ohno; M Nakagawa; S Nishimura; Koji Takeuchi; Susumu Okabe
Effect of 16,16-dimethyl prostaglandin E2 on gastric surface epithelial cell damage induced by 20% ethanol in rats.
Japanese journal of pharmacology 1987;45(3):327-34.
1987: Koji Takeuchi; H Nishiwaki; O Furukawa; Susumu Okabe
Cytoprotective action of histamine against 0.6 N HCl-induced gastric mucosal injury in rats; comparative study with adaptive cytoprotection induced by exogenous acid.
Japanese journal of pharmacology 1987;44(3):335-44.
1987: Koji Takeuchi; H Nishiwaki; Y Ishihara; Susumu Okabe
Roles of gastric motility changes in cytoprotection induced by acetazolamide and cysteamine in rats.
Japanese journal of pharmacology 1987;44(3):269-81.
1987: Koji Takeuchi; O Furukawa; H Tanaka; H Nishiwaki; Susumu Okabe
Impairment of acid-neutralizing capacity and lesion formation in the rat duodenum during hemorrhagic shock: comparative study with indomethacin.
Japanese journal of pharmacology 1987;44(2):163-70.