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Tomio Takeuchi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
108
Naganawa, Hiroshi
70
Hamada, M
52
Sawa, T
44
Aoyagi, T
39
Iinuma, Hironobu
34
Kondo, S
32
Takahashi, Y
24
Nakamura, Hikaru
23
Kinoshita, Naoko
23
Umezawa, Kazuo
23
Muraoka, Yasuhiko
22
Sawa, Ryuichi
21
Ikeda, Daishiro
20
Nishimura, Yoshio
17
Kojima, Fukiko

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Publications

TOP 3
Kunimoto Setsuko; Lu Jie; Esumi Hiroyasu; Yamazaki Yohko; Kinoshita Naoko; Honma Yoshiko; Hamada Masa; Ohsono Michiyo; Ishizuka Masaaki; Takeuchi Tomio
Kigamicins, novel antitumor antibiotics. I. Taxonomy, isolation, physico-chemical properties and biological activities.
Yamazaki Yohko; Egawa Kiyoshi; Nose Kiyoshi; Kunimoto Setsuko; Takeuchi Tomio
HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells.
Momose Isao; Sekizawa Ryuichi; Iinuma Hironobu; Takeuchi Tomio
Inhibition of proteasome activity by tyropeptin A in PC12 cells.

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All Publications

2003: Kunimoto Setsuko; Lu Jie; Esumi Hiroyasu; Yamazaki Yohko; Kinoshita Naoko; Honma Yoshiko; Hamada Masa; Ohsono Michiyo; Ishizuka Masaaki; Takeuchi Tomio
Kigamicins, novel antitumor antibiotics. I. Taxonomy, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 2003;56(12):1004-11.
2003: Yamazaki Yohko; Egawa Kiyoshi; Nose Kiyoshi; Kunimoto Setsuko; Takeuchi Tomio
HIF-1-dependent VEGF reporter gene assay by a stable transformant of CHO cells.
Biological & pharmaceutical bulletin 2003;26(4):417-20.
2002: Momose Isao; Sekizawa Ryuichi; Iinuma Hironobu; Takeuchi Tomio
Inhibition of proteasome activity by tyropeptin A in PC12 cells.
Bioscience, biotechnology, and biochemistry 2002;66(10):2256-8.
2002: Sekizawa Ryuichi; Ikeno Souichi; Nakamura Hikaru; Naganawa Hiroshi; Matsui Susumu; Iinuma Hironobu; Takeuchi Tomio
Panepophenanthrin, from a mushroom strain, a novel inhibitor of the ubiquitin-activating enzyme.
Journal of natural products 2002;65(10):1491-3.
2002: Adachi Hayamitsu; Nishimura Yoshio; Takeuchi Tomio
Synthesis and activities of bactobolin derivatives having new functionality at C-3.
The Journal of antibiotics 2002;55(1):92-8.
2001: Momose I; Sekizawa R; Hashizume H; Kinoshita N; Homma Y; Hamada M; Iinuma H; Takeuchi T
Tyropeptins A and B, new proteasome inhibitors produced by Kitasatospora sp. MK993-dF2. I. Taxonomy, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 2001;54(12):997-1003.
2001: Hashizume H; Igarashi M; Hattori S; Hori M; Hamada M; Takeuchi T
Tripropeptins, novel antimicrobial agents produced by Lysobacter sp. I. Taxonomy, isolation and biological activities.
The Journal of antibiotics 2001;54(12):1054-9.
2001: Momose I; Sekizawa R; Hirosawa S; Ikeda D; Naganawa H; Iinuma H; Takeuchi T
Tyropeptins A and B, new proteasome inhibitors produced by Kitasatospora sp. MK993-dF2. II. Structure determination and synthesis.
The Journal of antibiotics 2001;54(12):1004-12.
2001: Sekizawa R; Momose I; Kinoshita N; Naganawa H; Hamada M; Muraoka Y; Iinuma H; Takeuchi T
Isolation and structural determination of phepropeptins A, B, C, and D, new proteasome inhibitors, produced by Streptomyces sp.
The Journal of antibiotics 2001;54(11):874-81.
2001: Akiyama T; Abe M; Harada S; Kojima F; Sawa R; Takahashi Y; Naganawa H; Homma Y; Hamada M; Yamaguchi A; Aoyagi T; Muraoka Y; Takeuchi T
Sulphostin, a potent inhibitor for dipeptidyl peptidase IV from Streptomyces sp. MK251-43F3.
The Journal of antibiotics 2001;54(9):744-6.
2001: Kondo K I; Adachi H; Nishimura Y; Takeuchi T
N-alkyl-3-decarboxy-3-hydroxymethylsiastatin B, a new family of glycosidase inhibitors of gem-diamine 1-N-iminosugars.
Natural product letters 2001;15(6):371-5.
2000: Iijima M; Someno T; Amemiya M; Ishizuka M; Naganawa H; Takeuchi T
Biosynthesis of IC202C, a new siderophore with immunosuppressive activity.
The Journal of antibiotics 2000;53(12):1411-5.
2000: Shitara E; Nishimura Y; Nerome K; Hiramoto Y; Takeuchi T
Synthesis of 6-acetamido-5-amino- and -5-guanidino-3, 4-dehydro-N-(2-ethylbutyryl)- 3-piperidinecarboxylic acids related to zanamivir and oseltamivir, inhibitors of influenza virus neuraminidases.
Organic letters 2000;2(24):3837-40.
2000: Igarashi M; Nakamura H; Naganawa H; Takeuchi T
Tubelactomicin A, a novel 16-membered lactone antibiotic, from Nocardia sp. II. Structure elucidation.
The Journal of antibiotics 2000;53(10):1102-7.
2000: Igarashi M; Hayashi C; Homma Y; Hattori S; Kinoshita N; Hamada M; Takeuchi T
Tubelactomicin A, a novel 16-membered lactone antibiotic, from Nocardia sp. I. Taxonomy, production, isolation and biological properties.
The Journal of antibiotics 2000;53(10):1096-101.
2000: Hosokawa N; Naganawa H; Hamada M; Iinuma H; Takeuchi T; Tsuchiya K S; Hori M
New triene-ansamycins, thiazinotrienomycins F and G and a diene-ansamycin, benzoxazomycin.
The Journal of antibiotics 2000;53(9):886-94.
2000: Egawa K; Yamori T; Nosaka C; Kunimoto S; Takeuchi T; Nos K
Deoxynybomycin is a selective anti-tumor agent inducing apoptosis and inhibiting topoisomerase I.
Biological & pharmaceutical bulletin 2000;23(9):1036-40.
2000: Nishimura Y; Adachi H; Satoh T; Shitara E; Nakamura H; Kojima F; Takeuchi T
All eight stereoisomeric D-glyconic-delta-lactams: synthesis, conformational analysis, and evaluation as glycosidase inhibitors.
The Journal of organic chemistry 2000;65(16):4871-82.
2000: Matsumoto N; Agata N; Kuboki H; Iinuma H; Sawa T; Takeuchi T; Umezawa K
Inhibition of rat embryo histidine decarboxylase by epoxyquinomicins.
The Journal of antibiotics 2000;53(6):637-9.
2000: Hosokawa N; Iinuma H; Takeuchi T; Sato S; Yamori T; Tsuchiya K S; Hori M
Anticancer and some biological activities of thiazinotrienomycin B.
The Journal of antibiotics 2000;53(3):306-8.
2000: Hosokawa N; Momose I; Sekizawa R; Naganawa H; Iinuma H; Takeuchi T; Matsui S
New strobilurins O and P from a mushroom.
The Journal of antibiotics 2000;53(3):297-300.
2000: Momose I; Sekizawa R; Hosokawa N; Iinuma H; Matsui S; Nakamura H; Naganawa H; Hamada M; Takeuchi T
Melleolides K, L and M, new melleolides from Armillariella mellea.
The Journal of antibiotics 2000;53(2):137-43.
2000: Shitara E; Nishimura Y; Kojima F; Takeuchi T
gem-diamine 1-N-iminosugars of L-fucose-type, the extremely potent L-fucosidase inhibitors.
Bioorganic & medicinal chemistry 2000;8(2):343-52.
2000: Nishimura Y; Shitara E; Adachi H; Toyoshima M; Nakajima M; Okami Y; Takeuchi T
Flexible synthesis and biological activity of uronic acid-type gem-diamine 1-N-iminosugars: a new family of glycosidase inhibitors.
The Journal of organic chemistry 2000;65(1):2-11.
1999: Igarashi M; Shida T; Sasaki Y; Kinoshita N; Naganawa H; Hamada M; Takeuchi T
Vinylamycin, a new depsipeptide antibiotic, from Streptomyces sp.
The Journal of antibiotics 1999;52(10):873-9.
1999: Nosaka C; Kunimoto S; Takeuchi T
The decrease of cytochrome c oxidase activity by 15-deoxyspergualin results in enhancement of XTT reduction in cultured cells.
The Journal of antibiotics 1999;52(9):803-8.
1999: Momose I; Hirosawa S; Nakamura H; Naganawa H; Iinuma H; Ikeda D; Takeuchi T
Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. II. Structure determination.
The Journal of antibiotics 1999;52(9):787-96.
1999: Momose I; Iinuma H; Kinoshita N; Momose Y; Kunimoto S; Hamada M; Takeuchi T
Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. I. Taxonomy, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1999;52(9):781-6.
1999: Iijima M; Someno T; Ishizuka M; Sawa R; Naganawa H; Takeuchi T
IC202B and C, new siderophores with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19.
The Journal of antibiotics 1999;52(9):775-80.
1999: Hosokawa N; Naganawa H; Kasahara T; Hattori S; Hamada M; Takeuchi T; Yamamoto S; Tsuchiya K S; Hori M
Futalosine and its derivatives, new nucleoside analogs.
Chemical & pharmaceutical bulletin 1999;47(7):1032-4.
1999: Shitara E; Nishimura Y; Kojima F; Takeuchi T
A facile synthesis of D-glucose-type gem-diamine 1-N-iminosugars: a new family of glucosidase inhibitors.
Bioorganic & medicinal chemistry 1999;7(6):1241-6.
1999: Kunimoto S; Nosaka C; Takeuchi T
Stimulation of cellular XTT reduction by cytochrome oxidase inhibitors.
Biological & pharmaceutical bulletin 1999;22(6):660-1.
1999: Nosaka C; Kunimoto S; Masuda T; Ohsono M; Iinuma H; Tsuchida T; Hamada M; Takeuchi T
A new cytotoxic 2H-pyran compound produced by acid treatment of the fermentation broth of Streptomyces sp.
Biological & pharmaceutical bulletin 1999;22(5):546-8.
1999: Shitara E; Nishimura Y; Kojima F; Takeuchi T
A facile synthesis of D-galactose-type gem-diamine 1-N-iminosugar: a new family of galactosidase inhibitor.
The Journal of antibiotics 1999;52(3):348-50.
1999: Nosaka C; Kunimoto S; Atsumi S; Takeuchi T
Inhibition of nitric oxide synthase induction by 15-deoxyspergualin in a cultured macrophage cell line, J774A.1 [correction of J744A.1] activated with IFN-gamma and LPS.
The Journal of antibiotics 1999;52(3):297-304.
1999: Matsumoto N; Tsuchida T; Nakamura H; Sawa R; Takahashi Y; Naganawa H; Iinuma H; Sawa T; Takeuchi T; Shiro M
Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis MJ773-88K4. II. Structure determination.
The Journal of antibiotics 1999;52(3):276-80.
1999: Matsumoto N; Tsuchida T; Maruyama M; Kinoshita N; Homma Y; Iinuma H; Sawa T; Hamada M; Takeuchi T; Heida N; Yoshioka T
Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis MJ773-88K4. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1999;52(3):269-75.
1999: Iijima M; Someno T; Amemiya M; Sawa R; Naganawa H; Ishizuka M; Takeuchi T
IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19. II. Physico-chemical properties and structure elucidation.
The Journal of antibiotics 1999;52(1):25-8.
1999: Iijima M; Someno T; Imada C; Okami Y; Ishizuka M; Takeuchi T
IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19. I. Taxonomy, fermentation, isolation and biological activity.
The Journal of antibiotics 1999;52(1):20-4.
1999: Murakami S; Takahashi Y; Takeuchi T; Kodama Y; Aoyagi T
The absolute configuration of belactin A, a beta-lactone-containing serine carboxypeptidase inhibitor: importance of the beta-lactone structure for serine carboxypeptidase inhibition.
Journal of enzyme inhibition 1999;14(6):437-46.
1998: Matsumoto N; Momose I; Umekita M; Kinoshita N; Chino M; Iinuma H; Sawa T; Hamada M; Takeuchi T
Diperamycin, a new antimicrobial antibiotic produced by Streptomyces griseoaurantiacus MK393-AF2. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1998;51(12):1087-92.
1998: Matsumoto N; Iinuma H; Sawa T; Takeuchi T
Synthesis of anti-rheumatic agent epoxyquinomicin B.
Bioorganic & medicinal chemistry letters 1998;8(21):2945-8.
1998: Akiyama T; Nakamura K T; Takahashi Y; Naganawa H; Muraoka Y; Aoyagi T; Takeuchi T
Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. II. Structure determination.
The Journal of antibiotics 1998;51(6):586-8.
1998: Akiyama T; Harada S; Kojima F; Takahashi Y; Imada C; Okami Y; Muraoka Y; Aoyagi T; Takeuchi T
Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties.
The Journal of antibiotics 1998;51(6):553-9.
1998: Chino M; Nishikawa K; Yamada A; Ohsono M; Sawa T; Hanaoka F; Ishizuka M; Takeuchi T
Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth.
The Journal of antibiotics 1998;51(5):480-6.
1998: Akiyama T; Sawa R; Naganawa H; Muraoka Y; Aoyagi T; Takeuchi T
Epostatin, new inhibitor of dipeptidyl peptidase II, produced by streptomyces sp. MJ995-OF5 II. Structure elucidation.
The Journal of antibiotics 1998;51(3):372-3.
1998: Akiyama T; Harada S; Kojima F; Kinoshita N; Hamada M; Muraoka Y; Aoyagi T; Takeuchi T
Epostatin, new inhibitor of dipeptidyl peptidase II, produced by Streptomyces sp. MJ995-OF5. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties and biological properties.
The Journal of antibiotics 1998;51(3):253-60.
1998: Adachi H; Nishimura Y; Kondo S; Takeuchi T
Synthesis and activity of 3-epi-actinobolin.
The Journal of antibiotics 1998;51(2):202-9.
1998: Adachi H; Usui T; Nishimura Y; Kondo S; Ishizuka M; Takeuchi T
Synthesis and activities of bactobolin derivatives based on the alteration of the functionality at C-3 position.
The Journal of antibiotics 1998;51(2):184-8.
1998: Momose I; Kinoshita N; Sawa R; Naganawa H; Iinuma H; Hamada M; Takeuchi T
Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17.
The Journal of antibiotics 1998;51(2):130-5.
1998: Igarashi M; Tsuchida T; Kinoshita N; Kamijima M; Sawa R; Sawa T; Naganawa H; Hamada M; Takeuchi T; Yamazaki K; Ishizuka M
Cremimycin, a novel 19-membered macrocyclic lactam antibiotic, from Streptomyces sp.
The Journal of antibiotics 1998;51(2):123-9.
1998: Momose I; Chen W; Nakamura H; Naganawa H; Iinuma H; Takeuchi T
Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination.
The Journal of antibiotics 1998;51(1):26-32.
1998: Momose I; Chen W; Kinoshita N; Iinuma H; Hamada M; Takeuchi T
Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1998;51(1):21-5.
1997: Igarashi M; Nakamura H; Naganawa H; Takeuchi T
Resormycin, a novel herbicidal and antifungal antibiotic produced by a strain of Streptomyces platensis. II. Structure elucidation of resormycin.
The Journal of antibiotics 1997;50(12):1026-31.
1997: Igarashi M; Kinoshita N; Ikeda T; Kameda M; Hamada M; Takeuchi T
Resormycin, a novel herbicidal and antifungal antibiotic produced by a strain of Streptomyces platensis. I. Taxonomy, production, isolation and biological properties.
The Journal of antibiotics 1997;50(12):1020-5.
1997: Igarashi M; Nakamura H; Naganawa H; Takeuchi T
Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. II. Structure elucidation of formamicin.
The Journal of antibiotics 1997;50(11):932-6.
1997: Igarashi M; Kinoshita N; Ikeda T; Nakagawa E; Hamada M; Takeuchi T
Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. I. Taxonomy, production, isolation and biological properties.
The Journal of antibiotics 1997;50(11):926-31.
1997: Matsumoto N; Tsuchida T; Sawa R; Iinuma H; Nakamura H; Naganawa H; Sawa T; Takeuchi T
Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. III. Physico-chemical properties and structure determination.
The Journal of antibiotics 1997;50(11):912-5.
1997: Matsumoto N; Iinuma H; Sawa T; Takeuchi T; Hirano S; Yoshioka T; Ishizuka M
Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. II. Effect on type II collagen-induced arthritis in mice.
The Journal of antibiotics 1997;50(11):906-11.
1997: Matsumoto N; Tsuchida T; Umekita M; Kinoshita N; Iinuma H; Sawa T; Hamada M; Takeuchi T
Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities.
The Journal of antibiotics 1997;50(11):900-5.
1997: Chino M; Nishikawa K; Sawa R; Hamada M; Naganawa H; Sawa T; Takeuchi T
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2. III. Biosynthesis.
The Journal of antibiotics 1997;50(9):781-4.
1997: Nishizuka T; Hirosawa S; Hamada M; Kondo S; Ikeda D; Takeuchi T
Selective deoxygenation and O-methylation of benanomicin A: synthesis of 9-deoxy-, 9-O-methyl- and 14-O-methylbenanomicin A.
The Journal of antibiotics 1997;50(9):765-9.
1997: Nishizuka T; Hirosawa S; Kondo S; Ikeda D; Takeuchi T
A synthetic approach to benanomicin A. 2. Synthesis of the substituted 5,6-dihydrobenzo[a]naphthacenequinone.
The Journal of antibiotics 1997;50(9):755-64.
1997: Hirosawa S; Nishizuka T; Kondo S; Ikeda D; Takeuchi T
A synthetic approach to benanomicin A. 1. Synthesis of 5,6-dihydrobenzo[a]naphthacenequinone.
The Journal of antibiotics 1997;50(8):685-9.
1997: Kondo S; Nakamura H; Ikeda Y; Naganawa H; Maeda K; Takeuchi T
Structures of two remarkable dimerization products of sarkomycin.
The Journal of antibiotics 1997;50(4):363-5.
1997: Kawamura N; Nakamura H; Sawa R; Takahashi Y; Sawa T; Naganawa H; Takeuchi T
Pyralomicins, novel antibiotics from Microtetraspora spiralis. IV. Absolute configuration.
The Journal of antibiotics 1997;50(2):147-9.
1997: Chino M; Nishikawa K; Tsuchida T; Sawa R; Nakamura H; Nakamura K T; Muraoka Y; Ikeda D; Naganawa H; Sawa T; Takeuchi T
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 II. Structure determination of heliquinomycin.
The Journal of antibiotics 1997;50(2):143-6.
1997: Nagai M; Kojima F; Naganawa H; Hamada M; Aoyagi T; Takeuchi T
Phebestin, a new inhibitor of aminopeptidase N, produced by Streptomyces sp. MJ716-m3.
The Journal of antibiotics 1997;50(1):82-4.
1996: Tsuda M; Muraoka Y; Takeuchi T; Sekizawa R; Umezawa K
Stereospecific synthesis of a novel farnesyl protein transferase inhibitor, valinoctin A and its analogues.
The Journal of antibiotics 1996;49(10):1031-5.
1996: Tsuda M; Muraoka Y; Nagai M; Aoyagi T; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase. VIII. Endopeptidase inhibitory activity of non-peptidyl poststatin analogues.
The Journal of antibiotics 1996;49(10):1022-30.
1996: Tsuda M; Muraoka Y; Nagai M; Aoyagi T; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase. VII. N-cycloalkylamide analogues.
The Journal of antibiotics 1996;49(9):909-20.
1996: Tsuda M; Muraoka Y; Someno T; Nagai M; Aoyagi T; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase. VI. Endopeptidase inhibitory activity of poststatin analogues containing pyrrolidine ring.
The Journal of antibiotics 1996;49(9):900-8.
1996: Tsuda M; Muraoka Y; Nagai M; Aoyagi T; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase. V. Endopeptidase inhibitory activity of poststatin analogues.
The Journal of antibiotics 1996;49(9):890-9.
1996: Murakami S; Harada S; Takahashi Y; Naganawa H; Takeuchi T; Aoyagi T
Piperastatin B: a new selective serine carboxypeptidase inhibitor from Streptomyces lavendofoliae MJ908-WF13.
Journal of enzyme inhibition 1996;11(1):51-66.
1996: Chino M; Nishikawa K; Umekita M; Hayashi C; Yamazaki T; Tsuchida T; Sawa T; Hamada M; Takeuchi T
Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1996;49(8):752-7.
1996: Kawamura N; Kinoshita N; Sawa R; Takahashi Y; Sawa T; Naganawa H; Hamada M; Takeuchi T
Pyralomicins, novel antibiotics from Microtetraspora spiralis. I. Taxonomy and production.
The Journal of antibiotics 1996;49(7):706-9.
1996: Kawamura N; Sawa R; Takahashi Y; Isshiki K; Sawa T; Naganawa H; Takeuchi T
Pyralomicins, novel antibiotics from Microtetraspora spiralis. II. Structure determination.
The Journal of antibiotics 1996;49(7):651-6.
1996: Kawamura N; Sawa R; Takahashi Y; Sawa T; Naganawa H; Takeuchi T
Pyralomicins, novel antibiotics from Microtetraspora spiralis. III. Biosynthesis of pyralomicin 1a.
The Journal of antibiotics 1996;49(7):657-60.
1996: Satoh T; Nishimura Y; Kondo S; Takeuchi T
A practical synthesis from siastatin B of (3S,4S,5R,6R)- 4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic acid having antimetastatic activity in mice.
Carbohydrate research 1996;286():173-8.
1996: Sekizawa R; Iinuma H; Naganawa H; Hamada M; Takeuchi T; Yamaizumi J; Umezawa K
Isolation of novel saquayamycins as inhibitors of farnesyl-protein transferase.
The Journal of antibiotics 1996;49(5):487-90.
1996: Hosokawa N; Naganawa H; Hamada M; Takeuchi T; Ikeno S; Hori M
Hydroxymycotrienins A and B, new ansamycin group antibiotics.
The Journal of antibiotics 1996;49(5):425-31.
1996: Sekizawa R; Iinuma H; Muraoka Y; Naganawa H; Kinoshita N; Nakamura H; Hamada M; Takeuchi T; Umezawa K
Isolation and synthesis of novel farnesyl protein transferase inhibitors, valinoctins A and B, from Streptomyces strain MJ858-NF3.
Journal of natural products 1996;59(3):232-6.
1996: Tsuchida T; Umekita M; Kinoshita N; Iinuma H; Nakamura H; Nakamura K; Naganawa H; Sawa T; Hamada M; Takeuchi T
Epoxyquinomicins A and B, new antibiotics from Amycolatopsis.
The Journal of antibiotics 1996;49(3):326-8.
1996: Satoh T; Nishimura Y; Kondo S; Takeuchi T; Azetaka M; Fukuyasu H; Iizuka Y; Ohuchi S; Shibahara S
Synthesis and antimetastatic activity of 6-trichloroacetamido and 6-guanidino analogues of siastatin B.
The Journal of antibiotics 1996;49(3):321-5.
1996: Tsuda M; Muraoka Y; Nagai M; Takeuchi T; Aoyagi T
Poststatin, a new inhibitor of prolyl endopeptidase. IV. The chemical synthesis of poststain.
The Journal of antibiotics 1996;49(3):287-91.
1996: Nishimura Y; Satoh T; Kudo T; Kondo S; Takeuchi T
Synthesis and activity of 1-N-iminosugar inhibitors, siastatin B analogues for alpha-N-acetylgalactosaminidase and beta-N-acetylglucosaminidase.
Bioorganic & medicinal chemistry 1996;4(1):91-6.
1996: Kondo S; Ikeda Y; Takeuchi T; Shinei R; Gomi S; Shibahara S; Haraguchi Y; Ikeda R; Hoshino H
New bellenamine homologs inhibiting human immunodeficiency virus type I infectivity.
The Journal of antibiotics 1996;49(1):113-8.
1996: Murakami S; Takahashi Y; Naganawa H; Takeuchi T; Aoyagi T
Piperastatin A, a new selective serine carboxypeptidase inhibitor produced by actinomycete. II. Physico-chemical properties and structure determination.
Journal of enzyme inhibition 1996;10(2):105-14.
1996: Murakami S; Harada S; Yamazaki T; Takahashi Y; Hamada M; Takeuchi T; Aoyagi T
Piperastatin A, a new selective serine carboxypeptidase inhibitor produced by actinomycete. I. Taxonomy, production, isolation and biological activities.
Journal of enzyme inhibition 1996;10(2):93-103.
1995: Igarashi M; Chen W; Tsuchida T; Umekita M; Sawa T; Naganawa H; Hamada M; Takeuchi T
4'-Deacetyl-(-)-griseusins A and B, new naphthoquinone antibiotics from an actinomycete.
The Journal of antibiotics 1995;48(12):1502-5.
1995: Watanabe T; Takeuchi T; Otsuka M; Tanaka S; Umezawa K
Synthesis and protein tyrosine phosphatase inhibitory activity of dephostatin analogs.
The Journal of antibiotics 1995;48(12):1460-6.
1995: Tsuchida T; Iinuma H; Nakamura K T; Nakamura H; Sawa T; Hamada M; Takeuchi T
Derivatives of tetrodecamycin.
The Journal of antibiotics 1995;48(11):1330-5.
1995: Tsuchida T; Sawa R; Takahashi Y; Iinuma H; Sawa T; Naganawa H; Takeuchi T
Azicemicins A and B, new antimicrobial agents produced by Amycolatopsis. II. Structure determination.
The Journal of antibiotics 1995;48(10):1148-52.
1995: Tsuchida T; Iinuma H; Sawa R; Takahashi Y; Nakamura H; Nakamura K T; Sawa T; Naganawa H; Takeuchi T
Tetrodecamycin and dihydrotetrodecamycin, new antimicrobial antibiotics against Pasteurella piscicida produced by Streptomyces nashvillensis MJ885-mF8. II. Structure determination.
The Journal of antibiotics 1995;48(10):1110-4.
1995: Tsuchida T; Iinuma H; Nishida C; Kinoshita N; Sawa T; Hamada M; Takeuchi T
Tetrodecamycin and dihydrotetrodecamycin, new antimicrobial antibiotics against Pasteurella piscicida produced by Streptomyces nashvillensis MJ885-mF8. I. Taxonomy, fermentation, isolation, characterization and biological activities.
The Journal of antibiotics 1995;48(10):1104-9.
1995: Umezawa K; Masuoka S; Ohse T; Naganawa H; Kondo S; Ikeda Y; Kinoshita N; Hamada M; Sawa T; Takeuchi T
Isolation from Streptomyces of a novel naphthoquinone compound, naphthablin, that inhibits Abl oncogene functions.
The Journal of antibiotics 1995;48(7):604-7.
1995: Hosokawa N; Naganawa H; Inuma H; Hamada M; Takeuchi T; Kanbe T; Hori M
Thiazinotrienomycins, new ansamycin group antibiotics.
The Journal of antibiotics 1995;48(6):471-8.
1995: Igarashi M; Sasao C; Yoshida A; Naganawa H; Hamada M; Takeuchi T
Ochracenomicins A, B and C, new benz[a]anthraquinone antibiotics from Amicolatopsis sp.
The Journal of antibiotics 1995;48(4):335-7.
1995: Tsuchida T; Inuma H; Kinoshita N; Ikeda T; Sawa T; Hamada M; Takeuchi T
Azicemicins A and B, a new antimicrobial agent produced by Amycolatopsis. I. Taxonomy, fermentation, isolation, characterization and biological activities.
The Journal of antibiotics 1995;48(3):217-21.
1995: Ishizuka M; Kawatsu M; Yamashita T; Ueno M; Takeuchi T
Low molecular weight immunomodulators produced by microorganisms.
International journal of immunopharmacology 1995;17(2):133-39.
1995: Murakami S; Takahashi Y; Naganawa H; Takeuchi T; Aoyagi T
Belactins A and B, new serine carboxypeptidase inhibitors produced by Actinomycete. II. Physico-chemical properties, structure determinations and enzymatic inhibitory activities compared with other beta-lactone containing inhibitors.
Journal of enzyme inhibition 1995;9(4):277-84.
1995: Murakami S; Harada S; Kojima F; Kinoshita N; Takahashi Y; Hamada M; Takeuchi T; Aoyagi T
Belactins A and B, new serine carboxypeptidase inhibitors produced by Actinomycete. I. Taxonomy, production, isolation and biological activities.
Journal of enzyme inhibition 1995;9(4):263-75.
1995: Aoyama T; Kojima F; Imada C; Muraoka Y; Naganawa H; Okami Y; Takeuchi T; Aoyagi T
Pyrostatins A and B, new inhibitors of N-acetyl-beta-D-glucosaminidase, produced by Streptomyces sp. SA-3501.
Journal of enzyme inhibition 1995;8(4):223-32.
1994: Sawa R; Takahashi Y; Nakamura H; Nakamura K T; Naganawa H; Takeuchi T
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces. III. Determination of absolute configuration.
The Journal of antibiotics 1994;47(11):1280-3.
1994: Sawa R; Takahashi Y; Sawa T; Naganawa H; Takeuchi T
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces. II. Structure elucidation by NMR studies.
The Journal of antibiotics 1994;47(11):1273-9.
1994: Sawa R; Takahashi Y; Itoh S; Shimanaka K; Kinoshita N; Homma Y; Hamada M; Sawa T; Naganawa H; Takeuchi T
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.
The Journal of antibiotics 1994;47(11):1266-72.
1994: Shimanaka K; Takahashi Y; Iinuma H; Naganawa H; Takeuchi T
Novel antibiotics, amythiamicins. III. Structure elucidations of amythiamicins A, B and C.
The Journal of antibiotics 1994;47(10):1153-9.
1994: Shimanaka K; Takahashi Y; Iinuma H; Naganawa H; Takeuchi T
Novel antibiotics, amythiamicins. II. Structure elucidation of amythiamicin D.
The Journal of antibiotics 1994;47(10):1145-52.
1994: Kunimoto S; Takeuchi T
Kinetic studies of the interaction between spergualin or 15-deoxyspergualin and amine oxidase from bovine plasma.
The Journal of antibiotics 1994;47(10):1130-5.
1994: Odai H; Shindo K; Odagawa A; Mochizuki J; Hamada M; Takeuchi T
Inostamycins B and C, new polyether antibiotics.
The Journal of antibiotics 1994;47(8):939-41.
1994: Nishimura Y; Satoh T; Kondo S; Takeuchi T; Azetaka M; Fukuyasu H; Iizuka Y; Shibahara S
Effect on spontaneous metastasis of mouse Lewis lung carcinoma by a trifluoroacetamide analogue of siastatin B.
The Journal of antibiotics 1994;47(7):840-2.
1994: Kondo S; Ikeda Y; Ikeda D; Takeuchi T; Usui T; Ishii M; Kudo T; Gomi S; Shibahara S
Synthesis of 2''-amino-2''-deoxyarbekacin and its analogs having potent activity against methicillin-resistant Staphylococcus aureus.
The Journal of antibiotics 1994;47(7):821-32.
1994: Shimanaka K; Kinoshita N; Iinuma H; Hamada M; Takeuchi T
Novel antibiotics, amythiamicins. I. Taxonomy, fermentation, isolation, physico-chemical properties, and antimicrobial activity.
The Journal of antibiotics 1994;47(6):668-74.
1994: Amemiya M; Someno T; Sawa R; Naganawa H; Ishizuka M; Takeuchi T
Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. II. Physico-chemical properties and structure determination.
The Journal of antibiotics 1994;47(5):541-4.
1994: Amemiya M; Ueno M; Osono M; Masuda T; Kinoshita N; Nishida C; Hamada M; Ishizuka M; Takeuchi T
Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. I. Taxonomy, fermentation, isolation and biological activities.
The Journal of antibiotics 1994;47(5):536-40.
1994: Nishioka H; Imoto M; Imaoka T; Sawa T; Takeuchi T; Umezawa K
Antitumor effect of piericidin B1 N-oxide.
The Journal of antibiotics 1994;47(4):447-52.
1994: Nishimura Y; Kudo T; Kondo S; Takeuchi T; Tsuruoka T; Fukuyasu H; Shibahara S
Totally synthetic analogues of siastatin B. III. Trifluoroacetamide analogues having inhibitory activity for tumor metastasis.
The Journal of antibiotics 1994;47(1):101-7.
1993: Nishimura Y; Umezawa Y; Kondo S; Takeuchi T; Mori K; Kijima-Suda I; Tomita K; Sugawara K; Nakamura K
Synthesis of 3-episiastatin B analogues having anti-influenza virus activity.
The Journal of antibiotics 1993;46(12):1883-9.
1993: Kakeya H; Imoto M; Takahashi Y; Naganawa H; Takeuchi T; Umezawa K
Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination.
The Journal of antibiotics 1993;46(11):1716-9.
1993: Ueno M; Amemiya M; Someno T; Masuda T; Iinuma H; Naganawa H; Hamada M; Ishizuka M; Takeuchi T
IC101, extracellular matrix antagonist produced by Streptomyces sp. MJ202-72F3. Production, isolation, structure determination and biological activity.
The Journal of antibiotics 1993;46(11):1658-65.
1993: Aoyama T; Zhao W; Kojima F; Muraoka Y; Naganawa H; Takeuchi T; Aoyagi T
Cysfluoretin, a new inhibitor of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12.
The Journal of antibiotics 1993;46(9):1471-4.
1993: Ueno M; Yoshinaga I; Amemiya M; Someno T; Iinuma H; Ishizuaka M; Takeuchi T
Delaminomycins, novel extracellular matrix receptor antagonists. V. Biosynthesis.
The Journal of antibiotics 1993;46(9):1390-6.
1993: Imoto M; Kakeya H; Sawa T; Hayashi C; Hamada M; Takeuchi T; Umezawa K
Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization.
The Journal of antibiotics 1993;46(9):1342-6.
1993: Hosoya Y; Kameyama T; Naganawa H; Okami Y; Takeuchi T
Anisomycin and new congeners active against human tumor cell lines.
The Journal of antibiotics 1993;46(8):1300-2.
1993: Ueno M; Amemiya M; Yamazaki K; Iijima M; Osono M; Someno T; Iinuma H; Hamada M; Ishizuka M; Takeuchi T
Delaminomycins, novel extracellular matrix receptor antagonist. IV. Structure-activity relationships of delaminomycins and derivatives.
The Journal of antibiotics 1993;46(7):1156-62.
1993: Ueno M; Someno T; Sawa R; Iinuma H; Naganawa H; Ishizuka M; Takeuchi T
Delaminomycins, novel nonpeptide extracellular matrix receptor antagonist and a new class of potent immunomodulator. II. Physico-chemical properties and structure elucidation of delaminomycin A.
The Journal of antibiotics 1993;46(6):979-84.
1993: Ueno M; Someno T; Sawa R; Iinuma H; Naganawa H; Ishizuka M; Takeuchi T
Delaminomycins, novel extracellular matrix receptor antagonist. III. Physico-chemical properties and structure elucidation of delaminomycins B and C.
The Journal of antibiotics 1993;46(6):1020-3.
1993: Aoyama T; Kojima F; Abe F; Muraoka Y; Naganawa H; Takeuchi T; Aoyagi T
Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities.
The Journal of antibiotics 1993;46(6):914-20.
1993: Aoyama T; Kojima F; Yamazaki T; Tatee T; Abe F; Muraoka Y; Naganawa H; Aoyagi T; Takeuchi T
Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities.
The Journal of antibiotics 1993;46(5):712-8.
1993: Hosokawa N; Iinuma H; Naganawa H; Hamada M; Takeuchi T; Itoh T; Hori M
A new antibiotic, structurally related to leptomycin A, flattens the morphology of v-ras(ts) NRK cells.
The Journal of antibiotics 1993;46(4):676-8.
1993: Nishioka H; Sawa T; Takahashi Y; Naganawa H; Hamada M; Takeuchi T; Umezawa K
Isolation and structure determination of novel phosphatidylinositol turnover inhibitors, piericidin B5 and B5 N-oxide, from Streptomyces sp.
The Journal of antibiotics 1993;46(4):564-8.
1993: Kondo S; Tamura A; Gomi S; Ikeda Y; Takeuchi T; Mitsuhashi S
Structures of enzymatically modified products of arbekacin by methicillin-resistant. Staphylococcus aureus.
The Journal of antibiotics 1993;46(2):310-5.
1993: Kudo T; Nishimura Y; Kondo S; Takeuchi T
Syntheses of the potent inhibitors of neuraminidase, N-(1,2-dihydroxypropyl) derivatives of siastatin B and its 4-deoxy analogs.
The Journal of antibiotics 1993;46(2):300-9.
1992: Koyama Y; Huang S P; Ikeda D; Kondo S; Takeuchi T
Orally active pivaloyloxymethyl 3-(isoxazolidin-5-yl)cephalosporins.
The Journal of antibiotics 1992;45(12):1966-9.
1992: Huang S P; Koyama Y; Ikeda D; Kondo S; Takeuchi T
Synthesis and activity of potent 3-(isoxazolidin-5-yl)- and 3-(isoxazolidinium-5-yl)cephalosporins.
The Journal of antibiotics 1992;45(12):1939-48.
1992: Koyama Y; Huang S P; Ikeda D; Kondo S; Takeuchi T
Synthesis and activity of 3-(isoxazolin-5-yl)- and 3-(isoxazol-4-yl)cephalosporins.
The Journal of antibiotics 1992;45(12):1930-8.
1992: Ikeda Y; Naganawa H; Kondo S; Takeuchi T
Preparation of 13C and 15N labeled bellenamine and its degradation products.
The Journal of antibiotics 1992;45(12):1925-9.
1992: Ikeda Y; Naganawa H; Kondo S; Takeuchi T
Biosynthesis of bellenamine by Streptomyces nashvillensis using stable isotope labeled compounds.
The Journal of antibiotics 1992;45(12):1919-24.
1992: Ueno M; Iijima M; Masuda T; Kinoshita N; Iinuma H; Naganawa H; Hamada M; Ishizuka M; Takeuchi T
Dethymicin, a novel immunosuppressant isolated from an Amycolatopsis. Fermentation, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1992;45(12):1819-26.
1992: Hatsu M; Naganawa H; Aoyagi T; Takeuchi T; Kodama Y
The structure of pyrizinostatin.
The Journal of antibiotics 1992;45(12):1961-2.
1992: Aoyama T; Naganawa H; Muraoka Y; Aoyagi T; Takeuchi T
Biosynthesis of benastatin A.
The Journal of antibiotics 1992;45(11):1767-72.
1992: Ikeda Y; Gomi S; Hamada M; Kondo S; Takeuchi T
Production of bellenamine and new metabolites in a synthetic medium.
The Journal of antibiotics 1992;45(11):1763-6.
1992: Aoyagi T; Hatsu M; Imada C; Naganawa H; Okami Y; Takeuchi T
Pyrizinostatin: a new inhibitor of pyroglutamyl peptidase.
The Journal of antibiotics 1992;45(11):1795-6.
1992: Komagata D; Sawa R; Kinoshita N; Imada C; Sawa T; Naganawa H; Hamada M; Okami Y; Takeuchi T
Isolation of glutathione-S-transferase inhibitors.
The Journal of antibiotics 1992;45(10):1681-3.
1992: Kudo T; Nishimura Y; Kondo S; Takeuchi T
Syntheses and activities of N-substituted derivatives of siastatin B.
The Journal of antibiotics 1992;45(10):1662-8.
1992: Ikeda D; Nishizuka T; Huang S P; Kondo S; Takeuchi T
Amino acid analogs of benanomicin A through desalaninebenanomicin A.
The Journal of antibiotics 1992;45(10):1645-52.
1992: Aoyagi T; Aoyama T; Kojima F; Hattori S; Honma Y; Hamada M; Takeuchi T
Cyclooctatin, a new inhibitor of lysophospholipase, produced by Streptomyces melanosporofaciens MI614-43F2. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1992;45(10):1587-91.
1992: Iijima M; Masuda T; Nakamura H; Naganawa H; Kurasawa S; Okami Y; Ishizuka M; Takeuchi T; Iitake Y
Metacytofilin, a novel immunomodulator produced by Metarhizium sp. TA2759.
The Journal of antibiotics 1992;45(9):1553-6.
1992: Aoyagi T; Suda H; Uotani K; Kojima F; Aoyama T; Horiguchi K; Hamada M; Takeuchi T
Nagstatin, a new inhibitor of N-acetyl-beta-D-glucosaminidase, produced by Streptomyces amakusaensis MG846-fF3. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1992;45(9):1404-8.
1992: Aoyama T; Naganawa H; Muraoka Y; Nakamura H; Aoyagi T; Takeuchi T; Iitaka Y
Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. II. Structure determination of benastatins A and B.
The Journal of antibiotics 1992;45(9):1391-6.
1992: Aoyagi T; Aoyama T; Kojima F; Matsuda N; Maruyama M; Hamada M; Takeuchi T
Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1992;45(9):1385-90.
1992: Komagata D; Muraoka Y; Sawa R; Takahashi Y; Naganawa H; Sawa T; Takeuchi T
TA-3037A, a new inhibitor of glutathione S-transferase, produced by actinomycetes. II. Structure determination.
The Journal of antibiotics 1992;45(7):1122-4.
1992: Komagata D; Sawa T; Muraoka Y; Imada C; Okami Y; Takeuchi T
TA-3037A, a new inhibitor of glutathione S-transferase, produced by actinomycetes. I. Production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1992;45(7):1117-21.
1992: Aoyagi T; Osanai T; Wada T; Kojima F; Nagai M; Harada S; Takeuchi T; Nagai Y
Dose-dependent enzyme suppression in spleen induced by GM1 (monosialoganglioside 1) administration to mice.
Chemical & pharmaceutical bulletin 1992;40(7):1958-60.
1992: Hatsu M; Tuda M; Muraoka Y; Aoyagi T; Takeuchi T
Benarthin: a new inhibitor of pyroglutamyl peptidase. III. Synthesis and structure-activity relationships.
The Journal of antibiotics 1992;45(7):1088-95.
1992: Hatsu M; Naganawa H; Aoyagi T; Takeuchi T
Benarthin: a new inhibitor of pyroglutamyl peptidase. II. Physico-chemical properties and structure determination.
The Journal of antibiotics 1992;45(7):1084-7.
1992: Aoyagi T; Hatsu M; Kojima F; Hayashi C; Hamada M; Takeuchi T
Benarthin: a new inhibitor of pyroglutamyl peptidase. I. Taxonomy, fermentation, isolation and biological activities.
The Journal of antibiotics 1992;45(7):1079-83.
1992: Nishimura Y; Kudo T; Kondo S; Takeuchi T
Totally synthetic analogues of siastatin B. II. Optically active piperidine derivatives having trifluoroacetamide and hydroxyacetamide groups at C-2.
The Journal of antibiotics 1992;45(6):963-70.
1992: Kudo T; Nishimura Y; Kondo S; Takeuchi T
Totally synthetic analogues of siastatin B. I. Optically active 2-acetamidopiperidine derivatives.
The Journal of antibiotics 1992;45(6):954-62.
1992: Nishimura Y; Kondo S; Takeuchi T
Syntheses and activities of some bactobolin derivatives.
The Journal of antibiotics 1992;45(5):735-41.
1992: Sawa R; Takahashi Y; Itoh S; Shimanaka K; Matsuda N; Hamada M; Sawa T; Naganawa H; Takeuchi T
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces.
The Journal of antibiotics 1992;45(1):136-9.
1992: Kondo S; Gomi S; Uotani K; Miyakawa S; Inouye S; Ikeda D; Takeuchi T
New hydroxybenanomicins produced by Actinomadura.
Drugs under experimental and clinical research 1992;18(6):217-24.
1992: Ikeda D; Gomi S; Hamada M; Kondo S; Takeuchi T
Low toxic derivatives of istamycin B: synthesis and preliminary evaluation.
Drugs under experimental and clinical research 1992;18(6):205-16.
1991: Nagai M; Ogawa K; Muraoka Y; Naganawa H; Aoyagi T; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. II. Structure determination and inhibitory activities.
The Journal of antibiotics 1991;44(9):956-61.
1991: Aoyagi T; Nagai M; Ogawa K; Kojima F; Okada M; Ikeda T; Hamada M; Takeuchi T
Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1991;44(9):949-55.
1991: Nishioka H; Sawa T; Nakamura H; Iinuma H; Ikeda D; Sawa R; Naganawa H; Hayashi C; Hamada M; Takeuchi T
Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp.
Journal of natural products 1991;54(5):1321-5.
1991: Yoshida S; Aoyagi T; Takeuchi T
Biosynthetic study of leuhistin, a new inhibitor of aminopeptidase M.
The Journal of antibiotics 1991;44(6):683-4.
1991: Yoshida S; Naganawa H; Aoyagi T; Takeuchi T; Takeuchi Y; Kodama Y
Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. II. Structure determination of leuhistin.
The Journal of antibiotics 1991;44(6):579-81.
1991: Aoyagi T; Yoshida S; Matsuda N; Ikeda T; Hamada M; Takeuchi T
Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1991;44(6):573-8.
1991: Sawa R; Matsuda N; Uchida T; Ikeda T; Sawa T; Naganawa H; Hamada M; Takeuchi T
Dioxamycin, a new benz[a]anthraquinone antibiotic.
The Journal of antibiotics 1991;44(4):396-402.
1991: Kondo S; Gomi S; Uotani K; Inouye S; Takeuchi T
Isolation of new minor benanomicins.
The Journal of antibiotics 1991;44(2):123-9.
1991: Yoshida S; Aoyagi T; Harada S; Matsuda N; Ikeda T; Naganawa H; Hamada M; Takeuchi T
Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium.
The Journal of antibiotics 1991;44(1):111-2.
1990: Ajito K; Ikeda D; Nosaka C; Komuro K; Kondo S; Takeuchi T
Improved antitumor effects of 3'-deamino-3'-morpholino derivatives of pirarubicin.
The Journal of antibiotics 1990;43(11):1464-70.
1990: Shiomi K; Iinuma H; Naganawa H; Hamada M; Hattori S; Nakamura H; Takeuchi T; Iitaka Y
New antibiotic produced by Micromonospora globosa.
The Journal of antibiotics 1990;43(8):1000-5.
1990: Aoyagi T; Wada T; Kojima F; Nagai M; Harada S; Takeuchi T; Hirokawa K
Increase in aminobutyrate aminotransferase and cholineacetyltransferase in cerebrum of aged rats.
Chemical & pharmaceutical bulletin 1990;38(6):1750-2.
1990: Aoyagi T; Wada T; Nagai M; Kojima F; Harada S; Takeuchi T; Takahashi H; Hirokawa K; Tsumita T
Increased gamma-aminobutyrate aminotransferase activity in brain of patients with Alzheimer's disease.
Chemical & pharmaceutical bulletin 1990;38(6):1748-9.
1990: Kunimoto S; Komuro K; Nosaka C; Tsuchiya T; Fukatsu S; Takeuchi T
Biological activities of new anthracyclines containing fluorine, FAD104 and its metabolites.
The Journal of antibiotics 1990;43(5):556-65.
1990: Takahashi Y; Nakamura H; Ogata R; Matsuda N; Hamada M; Naganawa H; Takita T; Iitaka Y; Sato K; Takeuchi T
Kijimicin, a polyether antibiotic.
The Journal of antibiotics 1990;43(4):441-3.
1990: Yoshida S; Nakamura Y; Naganawa H; Aoyagi T; Takeuchi T
Probestin, a new inhibitor of aminopeptidase M, produced by Streptomyces azureus MH663-2F6. II. Structure determination of probestin.
The Journal of antibiotics 1990;43(2):149-53.
1990: Aoyagi T; Yoshida S; Nakamura Y; Shigihara Y; Hamada M; Takeuchi T
Probestin, a new inhibitor of aminopeptidase M, produced by Streptomyces azureus MH663-2F6. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1990;43(2):143-8.
1990: Umezawa K; Hori T; Tajima H; Imoto M; Isshiki K; Takeuchi T
Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors.
FEBS letters 1990;260(2):198-200.
1990: Atsumi S; Umezawa K; Iinuma H; Naganawa H; Nakamura H; Iitaka Y; Takeuchi T
Production, isolation and structure determination of a novel beta-glucosidase inhibitor, cyclophellitol, from Phellinus sp.
The Journal of antibiotics 1990;43(1):49-53.
1990: Onoda T; Isshiki K; Takeuchi T; Tatsuta K; Umezawa K
Inhibition of tyrosine kinase and epidermal growth factor receptor internalization by lavendustin A methyl ester in cultured A431 cells.
Drugs under experimental and clinical research 1990;16(6):249-53.
1989: Onoda T; Iinuma H; Sasaki Y; Hamada M; Isshiki K; Naganawa H; Takeuchi T; Tatsuta K; Umezawa K
Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus.
Journal of natural products 1989;52(6):1252-7.
1989: Kiyoshima K; Sakamoto M; Nomura H; Yoshioka T; Okamoto R; Sawa T; Naganawa H; Takeuchi T
Structure-activity relationship studies on 4''-O-acyltylosin derivatives: significance of their 23-O-mycinosyl and 4''-O-acyl moieties in antimicrobial activity against macrolide-resistant microbes.
The Journal of antibiotics 1989;42(11):1661-72.
1989: Takahashi A; Ikeda D; Nakamura H; Naganawa H; Kurasawa S; Okami Y; Takeuchi T; IitakaY
Altemicidin, a new acaricidal and antitumor substance. II. Structure determination.
The Journal of antibiotics 1989;42(11):1562-6.
1989: Takahashi A; Kurasawa S; Ikeda D; Okami Y; Takeuchi T
Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1989;42(11):1556-61.
1989: Aoyagi T; Wada T; Iinuma H; Ogawa K; Kojima F; Takeuchi T; Kuroda H; Ohbayashi A
Suppression of the activities of T-lymphocyte-related enzymes in spleen by administration of an immunosuppressant, 15-deoxyspergualin.
Biochemistry international 1989;19(4):821-6.
1989: Takagi Y; Kobayashi N; Tsuchiya T; Umezawa S; Takeuchi T; Komuro K; Nosaka C
Syntheses and antitumor activities of 7-O-(6-deoxy-2-O-methyl-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone.
The Journal of antibiotics 1989;42(8):1318-20.
1989: Takagi Y; Park H; Tsuchiya T; Umezawa S; Takeuchi T; Komuro K; Nosaka C
Syntheses and antitumor activities of 7-O-(3-amino-2,3,6-trideoxy-2-fluoro-alpha-L-talopyranosyl)daunomvcinone and -adriamycinone.
The Journal of antibiotics 1989;42(8):1315-7.
1989: Ajito K; Ikeda D; Komuro K; Nosaka C; Wako N; Kondo S; Takeuchi T
N-salicylidene derivatives of pirarubicin.
The Journal of antibiotics 1989;42(7):1133-44.
1989: Koyama Y; Huang S P; Ikeda D; Hamada M; Kondo S; Takeuchi T
Orally absorbable D-forphenicinol-cephalosporins.
The Journal of antibiotics 1989;42(6):993-9.
1989: Aoyagi T; Yamamoto T; Kojiri K; Morishima H; Nagai M; Hamada M; Takeuchi T; Umezawa H
Mannostatins A and B: new inhibitors of alpha-D-mannosidase, produced by Streptoverticillium verticillus var. quintum ME3-AG3: taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1989;42(6):883-9.
1989: Nishioka H; Imoto M; Sawa T; Hamada M; Naganawa H; Takeuchi T; Umezawa K
Screening of phosphatidylinositol kinase inhibitors from Streptomyces.
The Journal of antibiotics 1989;42(5):823-5.
1989: Kiyoshima K; Sakamoto M; Ishikura T; Fukagawa Y; Yoshioka T; Naganawa H; Sawa T; Takeuchi T
Application of dibutyltin oxide method to regioselective acylation and alkylation of tylosin at C-4''.
Chemical & pharmaceutical bulletin 1989;37(4):861-5.
1989: Dobashi K; Yang J X; Ogata R; Takahashi Y; Matsuda N; Hamada M; Naganawa H; Takita T; Takeuchi T
The structure of hidamicin, a polyether antibiotic.
The Journal of antibiotics 1989;42(4):629-32.
1989: Ajito K; Atsumi S; Ikeda D; Kondo S; Takeuchi T; Umezawa K
Inhibition of human immunodeficiency virus-associated reverse transcriptase by 14-O-acyladriamycins.
The Journal of antibiotics 1989;42(4):611-9.
1989: Kojiri K; Morishima H; Yamamoto T; Aoyagi T; Takeuchi T; Umezawa H
Structure determination of alphostatin, a novel alkaline phosphatase inhibitor.
The Journal of antibiotics 1989;42(3):489-90.
1989: Isshiki K; Sawa T; Naganawa H; Matsuda N; Hattori S; Hamada M; Takeuchi T; Oosono M; Ishizuka M; Yang Z Z
3-O-isobutyrylkinamycin C and 4-deacetyl-4-O-isobutyrylkinamycin C, new antibiotics produced by a Saccharothrix species.
The Journal of antibiotics 1989;42(3):467-9.
1989: Aoyagi T; Morishima H; Kojiri K; Yamamoto T; Kojima F; Nagaoka K; Hamada M; Takeuchi T; Umezawa H
Alphostatin, an inhibitor of alkaline phosphatase of bovine liver produced by Bacillus megaterium.
The Journal of antibiotics 1989;42(3):486-8.
1989: Itoh O; Kuroiwa S; Atsumi S; Umezawa K; Takeuchi T; Hori M
Induction by the guanosine analogue oxanosine of reversion toward the normal phenotype of K-ras-transformed rat kidney cells.
Cancer research 1989;49(4):996-1000.
1989: Aoyagi T; Wada T; Kojima F; Nagai M; Yoshida S; Sato T; Takeuchi T
Possible relationship between poly(ADP-ribose)synthetase and formation of antibody against acetylcholine receptors in patients with myasthenia gravis.
Biochemistry international 1989;18(2):391-8.
1989: Kunimoto S; Nosaka C; Xu C Z; Takeuchi T
Serum effect on cellular uptake of spermidine, spergualin, 15-deoxyspergualin, and their metabolites by L5178Y cells.
The Journal of antibiotics 1989;42(1):116-22.
1989: Umezawa K; Imoto M; Yamashita T; Sawa T; Takeuchi T
Modification of cellular membrane functions by pendolmycin.
Japanese journal of cancer research : Gann 1989;80(1):15-8.
1988: Yoshioka T; Kiyoshima K; Maeda M; Sakamoto M; Ishikura T; Fukagawa Y; Sawa T; Hamada M; Naganawa H; Takeuchi T
Synthesis and structure-activity studies of new 4''-O-acyltylosin derivatives of therapeutic interest.
The Journal of antibiotics 1988;41(11):1617-28.
1988: Dobashi K; Naganawa H; Takahashi Y; Takita T; Takeuchi T
Novel antifungal antibiotics octacosamicins A and B. II. The structure elucidation using various NMR spectroscopic methods.
The Journal of antibiotics 1988;41(11):1533-41.
1988: Dobashi K; Matsuda N; Hamada M; Naganawa H; Takita T; Takeuchi T
Novel antifungal antibiotics octacosamicins A and B. I. Taxonomy, fermentation and isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1988;41(11):1525-32.
1988: Takahashi A; Nakamura H; Ikeda D; Naganawa H; Kameyama T; Kurasawa S; Okami Y; Takeuchi T; Iitaka Y
Thrazarine, a new antitumor antibiotic. II. Physico-chemical properties and structure determination.
The Journal of antibiotics 1988;41(11):1568-74.
1988: Kameyama T; Takahashi A; Matsumoto H; Kurasawa S; Hamada M; Okami Y; Ishizuka M; Takeuchi T
Thrazarine, a new antitumor antibiotic. I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 1988;41(11):1561-7.
1988: Shigihara Y; Koizumi Y; Tamamura T; Homma Y; Isshiki K; Dobashi K; Naganawa H; Takeuchi T
6-Deoxy-8-O-methylrabelomycin and 8-O-methylrabelomycin from a Streptomyces species.
The Journal of antibiotics 1988;41(9):1260-4.
1988: Yoshida S; Naganawa H; Aoyagi T; Takeuchi T; Umezawa H
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination.
The Journal of antibiotics 1988;41(8):1015-8.
1988: Aoyagi T; Yoshida S; Harada S; Okuyama A; Nakayama C; Yoshida T; Hamada M; Takeuchi T; Umezawa H
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
The Journal of antibiotics 1988;41(8):1009-14.
1988: Tsuchiya T; Takagi Y; Umezawa S; Takeuchi T; Komuro K; Nosaka C; Umezawa H; Fukatsu S; Yoneta T
Synthesis and antitumor activities of 14-O-acyl derivatives of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)adriamycinone.
The Journal of antibiotics 1988;41(7):988-91.
1988: Takeuchi T; Hara T; Naganawa H; Okada M; Hamada M; Umezawa H; Gomi S; Sezaki M; Kondo S
New antifungal antibiotics, benanomicins A and B from an actinomycete.
The Journal of antibiotics 1988;41(6):807-11.
1988: Kunimoto S; Takahashi Y; Uchida T; Takeuchi T; Umezawa H
Strong binding of ditrisarubicin B to DNA.
The Journal of antibiotics 1988;41(5):655-9.
1988: Tamamura T; Tsuchiya M; Isshiki K; Sawa T; Takeuchi T; Hori M; Sakata N
Terpentecin, an inhibitor of DNA synthesis.
The Journal of antibiotics 1988;41(5):648-54.
1988: Imoto M; Yamashita T; Sawa T; Kurasawa S; Naganawa H; Takeuchi T; Bao-quan Z; Umezawa K
Inhibition of cellular phosphatidylinositol turnover by psi-tectorigenin.
FEBS letters 1988;230(1-2):43-6.
1988: Uchida T; Imoto M; Takahashi Y; Odagawa A; Sawa T; Tatsuta K; Naganawa H; Hamada M; Takeuchi T; Umezawa H
New potent anthracyclines, barminomycins I and II.
The Journal of antibiotics 1988;41(3):404-8.
1988: Omoto S; Kondo S; Fukatsu S; Takeuchi T; Umezawa K; Tsuchiya T; Umezawa S
Biological properties of ME2303 (FAD-104), a new anthracycline.
Drugs under experimental and clinical research 1988;14(7):435-9.
1988: Umezawa K; Takeuchi T; Komuro K; Nosaka C; Kunimoto S; Tsuchiya T; Takagi Y; Umezawa S; Umezawa H
Antitumour activity of new semi-synthetic anthracyclines containing fluorotalopyranose.
Drugs under experimental and clinical research 1988;14(7):429-34.
1988: Atsumi S; Muraoka Y; Nogami T; Hoshino H; Takeuchi T; Umezawa K
Inhibition of human immunodeficiency virus-associated reverse transcriptase by aminoacridines.
Drugs under experimental and clinical research 1988;14(12):719-22.
1987: Shiomi K; Iinuma H; Naganawa H; Isshiki K; Takeuchi T; Umezawa H
Biosynthesis of napyradiomycins.
The Journal of antibiotics 1987;40(12):1740-5.
1987: Takahashi A; Nakamura H; Kameyama T; Kurasawa S; Naganawa H; Okami Y; Takeuchi T; Umezawa H; Iitaka Y
Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination.
The Journal of antibiotics 1987;40(12):1671-6.
1987: Kameyama T; Takahashi A; Kurasawa S; Ishizuka M; Okami Y; Takeuchi T; Umezawa H
Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological properties.
The Journal of antibiotics 1987;40(12):1664-70.
1987: Kunimoto S; Xu C Z; Naganawa H; Hamada M; Masuda T; Takeuchi T; Umezawa H
Reversal of resistance by N-acetyltyramine or N-acetyl-2-phenylethylamine in doxorubicin-resistant leukemia P388 cells.
The Journal of antibiotics 1987;40(11):1651-2.
1987: Masuda T; Mizutani S; Iijima M; Odai H; Suda H; Ishizuka M; Takeuchi T; Umezawa H
Immunosuppressive activity of 15-deoxyspergualin and its effect on skin allografts in rats.
The Journal of antibiotics 1987;40(11):1612-8.
1987: Imoto M; Umezawa K; Sawa T; Takeuchi T; Umezawa H
In situ inhibition of tyrosine protein kinase by erbstatin.
Biochemistry international 1987;15(5):989-95.
1987: Imoto M; Umezawa K; Isshiki K; Kunimoto S; Sawa T; Takeuchi T; Umezawa H
Kinetic studies of tyrosine kinase inhibition by erbstatin.
The Journal of antibiotics 1987;40(10):1471-3.
1987: Isshiki K; Takahashi Y; Iinuma H; Naganawa H; Umezawa Y; Takeuchi T; Umezawa H; Nishimura S; Okada N; Tatsuta K
Synthesis of azepinomycin and its beta-D-ribofuranoside.
The Journal of antibiotics 1987;40(10):1461-3.
1987: Takeuchi T; Sawa T; Naganawa H; Hamada M; Umezawa H; Yoshioka T; Kiyoshima K; Iguchi H; Sakamoto M; Shimauchi Y
4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance.
The Journal of antibiotics 1987;40(9):1358-60.
1987: Shiomi K; Nakamura H; Iinuma H; Naganawa H; Takeuchi T; Umezawa H; Iitaka Y
New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins.
The Journal of antibiotics 1987;40(9):1213-9.
1987: Isshiki K; Imoto M; Sawa T; Umezawa K; Takeuchi T; Umezawa H; Tsuchida T; Yoshioka T; Tatsuta K
Inhibition of tyrosine protein kinase by synthetic erbstatin analogs.
The Journal of antibiotics 1987;40(8):1209-10.
1987: Isshiki K; Imoto M; Takeuchi T; Umezawa H; Tsuchida T; Yoshioka T; Tatsuta K
Effective synthesis of erbstatin and its analogs.
The Journal of antibiotics 1987;40(8):1207-8.
1987: Isshiki K; Takahashi Y; Sawa T; Naganawa H; Takeuchi T; Umezawa H; Tatsuta K
Total synthesis of indisocin and N-methylindisocin.
The Journal of antibiotics 1987;40(8):1202-3.
1987: Isshiki K; Takahashi Y; Sawa T; Naganawa H; Takeuchi T; Umezawa H; Tatsuta K
One-pot preparation of 1-chlorovinylisocyanides from carbonyl compounds.
The Journal of antibiotics 1987;40(8):1199-201.
1987: Isshiki K; Takahashi Y; Okada M; Sawa T; Hamada M; Naganawa H; Takita T; Takeuchi T; Umezawa H; Yamamoto M
A new antibiotic indisocin and N-methylindisocin.
The Journal of antibiotics 1987;40(8):1195-8.
1987: Kiyoshima K; Takada K; Yamamoto M; Kubo K; Okamoto R; Fukagawa Y; Ishikura T; Naganawa H; Sawa T; Takeuchi T
New tylosin analogs produced by mutants of Streptomyces fradiae.
The Journal of antibiotics 1987;40(8):1123-30.
1987: Umezawa K; Takeuchi T
Spergualin: a new antitumour antibiotic.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1987;41(5):227-32.
1987: Umezawa K; Kunimoto S; Takeuchi T
Experimental studies of new anthracyclines: aclacinomycin, THP-adriamycin and ditrisarubicins.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1987;41(5):206-13.
1986: Isshiki K; Tamamura T; Sawa T; Naganawa H; Takeuchi T; Umezawa H
Biosynthetic studies of terpentecin.
The Journal of antibiotics 1986;39(11):1634-5.
1985: Isshiki K; Tamamura T; Takahashi Y; Sawa T; Naganawa H; Takeuchi T; Umezawa H
The structure of a new antibiotic, terpentecin.
The Journal of antibiotics 1985;38(12):1819-21.
1985: Tamamura T; Sawa T; Isshiki K; Masuda T; Homma Y; Inuma H; Naganawa H; Hamada M; Takeuchi T; Umezawa H
Isolation and characterization of terpentecin, a new antitumor antibiotic.
The Journal of antibiotics 1985;38(12):1664-9.
1985: Kanai F; Isshiki K; Umezawa Y; Morishima H; Naganawa H; Takita T; Takeuchi T; Umezawa H
Vanoxonin, a new inhibitor of thymidylate synthetase. II. Structure determination and total synthesis.
The Journal of antibiotics 1985;38(1):31-8.
1984: Kunimoto S; Miura K; Umezawa K; Xu C Z; Masuda T; Takeuchi T; Umezawa H
Cellular uptake and efflux and cytostatic activity of 4'-O-tetrahydropyranyladriamycin in adriamycin-sensitive and resistant tumor cell lines.
The Journal of antibiotics 1984;37(12):1697-702.
1983: Tanaka H; Yoshioka T; Yoshimoto A; Shimauchi Y; Ishikura T; Takeuchi T; Umezawa H
Chemical modification of anthracycline antibiotics. V. Synthesis of 2-hydroxyaclacinomycin A by chemical glycosidation.
The Journal of antibiotics 1983;36(5):601-3.
1983: Umezawa H; Okami Y; Kurasawa S; Ohnuki T; Ishizuka M; Takeuchi T; Shiio T; Yugari Y
Marinactan, antitumor polysaccharide produced by marine bacteria.
The Journal of antibiotics 1983;36(5):471-7.
1982: Okamoto R; Kiyoshima K; Yamamoto M; Takada K; Ohnuki T; Ishikura T; Naganawa H; Tatsuta K; Takeuchi T; Umezawa H
New macrolide antibiotics produced by mutants from Streptomyces fradiae NRRL 2702.
The Journal of antibiotics 1982;35(7):921-4.

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