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Thierry Boon

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Arcadi Cipponi; Pierre G Coulie; Marjorie Mercier; Teofila Seremet; Marguerite Stas; Ivan Théate; Jean-François Baurain; Thierry Boon; Joost van den Oord; Nicolas van Baren
Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases.
Wenbin Ma; Vincent Stroobant; Nathalie Vigneron; Thierry Boon; Jacques Chapiro; Pierre G Coulie; Catherine Germeau; Benoît J Van den Eynde
A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy.
Violaine François; Sabrina Ottaviani; Nicolina Renkvist; Julie Stockis; Gerold Schuler; Kris Thielemans; Didier Colau; Marie Marchand; Thierry Boon; Sophie Lucas; Pierre van der Bruggen
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.

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2012: Arcadi Cipponi; Pierre G Coulie; Marjorie Mercier; Teofila Seremet; Marguerite Stas; Ivan Théate; Jean-François Baurain; Thierry Boon; Joost van den Oord; Nicolas van Baren
Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases.
Cancer research 2012;72(16):3997-4007.
2011: Wenbin Ma; Vincent Stroobant; Nathalie Vigneron; Thierry Boon; Jacques Chapiro; Pierre G Coulie; Catherine Germeau; Benoît J Van den Eynde
A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy.
International journal of cancer. Journal international du cancer 2011;129(10):2427-34.
2009: Violaine François; Sabrina Ottaviani; Nicolina Renkvist; Julie Stockis; Gerold Schuler; Kris Thielemans; Didier Colau; Marie Marchand; Thierry Boon; Sophie Lucas; Pierre van der Bruggen
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.
Cancer research 2009;69(10):4335-45.
2009: Julie Stockis; Wolfram Fink; Violaine François; Thierry Connerotte; Charles de Smet; Laurent Knoops; Pierre van der Bruggen; Thierry Boon; Pierre G Coulie; Sophie Lucas
Comparison of stable human Treg and Th clones by transcriptional profiling.
European journal of immunology 2009;39(3):869-82.
2008: Nathalie Demotte; Vincent Stroobant; Pierre J Courtoy; Patrick Van Der Smissen; Didier Colau; Immanuel F Luescher; Claire Hivroz; Julie Nicaise; Jean-Luc Squifflet; Michel Mourad; Danièle Godelaine; Thierry Boon; Pierre van der Bruggen
Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.
Immunity 2008;28(3):414-24.
2008: Javier Carrasco; Aline Van Pel; Bart Neyns; Bernard Lethé; Francis Brasseur; Nicolina Renkvist; Pierre van der Bruggen; Nicolas van Baren; Robert Paulus; Kris Thielemans; Thierry Boon; Danièle Godelaine
Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3585-93.
2007: Danièle Godelaine; Javier Carrasco; Francis Brasseur; Bart Neyns; Kris Thielemans; Thierry Boon; Aline Van Pel
A new tumor-specific antigen encoded by MAGE-C2 and presented to cytolytic T lymphocytes by HLA-B44.
Cancer immunology, immunotherapy : CII 2007;56(6):753-9.
2007: Pierre van der Bruggen; Catia Traversari; Patrick Chomez; Christophe Lurquin; Etienne De Plaen; Benoît J Van den Eynde; Alexander Knuth; Thierry Boon
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2617-21.
2007: Tomoko So; Takeshi Hanagiri; Jacques Chapiro; Didier Colau; Francis Brasseur; Kosei Yasumoto; Thierry Boon; Pierre G Coulie
Lack of tumor recognition by cytolytic T lymphocyte clones recognizing peptide 195-203 encoded by gene MAGE-A3 and presented by HLA-A24 molecules.
Cancer immunology, immunotherapy : CII 2007;56(2):259-69.
2006: Javier Carrasco; Danièle Godelaine; Aline Van Pel; Thierry Boon; Pierre van der Bruggen
CD45RA on human CD8 T cells is sensitive to the time elapsed since the last antigenic stimulation.
Blood 2006;108(9):2897-905.
2006: Zhaojun Sun; Bernard Lethé; Yi Zhang; Vincenzo Russo; Didier Colau; Vincent Stroobant; Thierry Boon; Pierre van der Bruggen
A new LAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-A68 tumors.
Cancer immunology, immunotherapy : CII 2006;55(6):644-52.
2006: Mitsuhiro Takenoyama; Jean-Françis Baurain; Manabu Yasuda; Tetsuya So; Masakazu Sugaya; Takeshi Hanagiri; Kenji Sugio; Kosei Yasumoto; Thierry Boon; Pierre G Coulie
A point mutation in the NFYC gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human squamous cell lung carcinoma.
International journal of cancer. Journal international du cancer 2006;118(8):1992-7.
2006: Axelle Loriot; Etienne De Plaen; Thierry Boon; Charles De Smet
Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells.
The Journal of biological chemistry 2006;281(15):10118-26.
2006: Takeshi Hanagiri; Nicolas van Baren; Bart Neyns; Thierry Boon; Pierre G Coulie
Analysis of a rare melanoma patient with a spontaneous CTL response to a MAGE-A3 peptide presented by HLA-A1.
Cancer immunology, immunotherapy : CII 2006;55(2):178-84.
2006: Jacques Chapiro; Stéphane Claverol; Fanny Piette; Wenbin Ma; Vincent Stroobant; Benoît Guillaume; Jean Edouard Gairin; Sandra Morel; Odile Burlet-Schiltz; Bernard Monsarrat; Thierry Boon; Benoît J Van den Eynde
Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(2):1053-61.
2006: Thierry Boon; Pierre G Coulie; Benoît J Van den Eynde; Pierre van der Bruggen
Human T cell responses against melanoma.
Annual review of immunology 2006;24():175-208.
2005: Nicolas van Baren; Marie-Claude Bonnet; Brigitte Dréno; Amir Khammari; Thierry Dorval; Sophie Piperno-Neumann; Danielle Liénard; Daniel Speiser; Marie Marchand; Vincent G Brichard; Bernard Escudier; Sylvie Négrier; Pierre-Yves Dietrich; Dominique Maraninchi; Susanne Osanto; Ralf G Meyer; Gerd Ritter; Philippe Moingeon; Jim Tartaglia; Pierre van der Bruggen; Pierre G Coulie; Thierry Boon
Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(35):9008-21.
2005: Nathalie Zammatteo; Caroline Davril; Francis Brasseur; Sandrine Hamels; Etienne De Plaen; Thierry Boon; José Remacle
Unambiguous identification of the expressed MAGE-A genes on a DNA microarray.
Clinical chemistry 2005;51(12):2420-1.
2005: Sabrina Ottaviani; Yi Zhang; Thierry Boon; Pierre van der Bruggen
A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells.
Cancer immunology, immunotherapy : CII 2005;54(12):1214-20.
2005: Wim H J Kruit; Heidi H van Ojik; Vincent G Brichard; Bernard Escudier; Thierry Dorval; Brigitte Dréno; Poulam Patel; Nicolas van Baren; Marie-Françoise Avril; Sophie Piperno; Amir Khammari; Marguerite Stas; Gerd Ritter; Bernard Lethé; Danièle Godelaine; Francis Brasseur; Yi Zhang; Pierre van der Bruggen; Thierry Boon; Alexander M M Eggermont; Marie Marchand
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma.
International journal of cancer. Journal international du cancer 2005;117(4):596-604.
2005: Yi Zhang; Nicolina Renkvist; Zhaojun Sun; Beatrice Schuler-Thurner; Nicolas Glaichenhaus; Gerold Schuler; Thierry Boon; Pierre van der Bruggen; Didier Colau
A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells.
European journal of immunology 2005;35(4):1066-75.
2005: Yi Zhang; Zhaojun Sun; hugues nicolay; Ralf G Meyer; Nicolina Renkvist; Vincent Stroobant; Jurgen Corthals; Javier Carrasco; Alexander M M Eggermont; Marie Marchand; Kris Thielemans; Thomas Wölfel; Thierry Boon; Pierre van der Bruggen
Monitoring of anti-vaccine CD4 T cell frequencies in melanoma patients vaccinated with a MAGE-3 protein.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(4):2404-11.
2005: Carmen Brenner; Rachel Deplus; Céline Didelot; Axelle Loriot; Emmanuelle Viré; Charles De Smet; Arantxa Gutierrez; Davide Danovi; David Bernard; Thierry Boon; Pier Giuseppe Pelicci; Bruno Amati; Tony Kouzarides; Yvan de Launoit; Luciano Di Croce; François Fuks
Myc represses transcription through recruitment of DNA methyltransferase corepressor.
The EMBO journal 2005;24(2):336-46.
2005: Christophe Lurquin; Bernard Lethé; Etienne De Plaen; Véronique Corbière; Ivan Théate; Nicolas van Baren; Pierre G Coulie; Thierry Boon
Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen.
The Journal of experimental medicine 2005;201(2):249-57.
2005: Catherine Germeau; Wenbin Ma; Francesca Schiavetti; Christophe Lurquin; Emmanuelle Henry; Nathalie Vigneron; Francis Brasseur; Bernard Lethé; Etienne De Plaen; Thierry Velu; Thierry Boon; Pierre G Coulie
High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens.
The Journal of experimental medicine 2005;201(2):241-8.
2004: Christophe Lonchay; Pierre van der Bruggen; Thierry Connerotte; Takeshi Hanagiri; Pierre G Coulie; Didier Colau; Sophie Lucas; Aline Van Pel; Kris Thielemans; Nicolas van Baren; Thierry Boon
Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14631-8.
2004: Charles De Smet; Axelle Loriot; Thierry Boon
Promoter-dependent mechanism leading to selective hypomethylation within the 5' region of gene MAGE-A1 in tumor cells.
Molecular and cellular biology 2004;24(11):4781-90.
2004: Véronique Corbière; hugues nicolay; V Russo; Vincent Stroobant; Vincent G Brichard; Thierry Boon; Pierre van der Bruggen
Identification of a MAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-B*5701 tumors.
Tissue antigens 2004;63(5):453-7.
2004: Wenbin Ma; Catherine Germeau; Nathalie Vigneron; Anne-Sophie Maernoudt; Sandra Morel; Thierry Boon; Pierre G Coulie; Benoît J Van den Eynde
Two new tumor-specific antigenic peptides encoded by gene MAGE-C2 and presented to cytolytic T lymphocytes by HLA-A2.
International journal of cancer. Journal international du cancer 2004;109(5):698-702.
2004: Nathalie Vigneron; Vincent Stroobant; Jacques Chapiro; Annie Ooms; Gérard Degiovanni; Sandra Morel; Pierre van der Bruggen; Thierry Boon; Benoît J Van den Eynde
An antigenic peptide produced by peptide splicing in the proteasome.
Science (New York, N.Y.) 2004;304(5670):587-90.
2004: Sandra Laduron; Rachel Deplus; Sifang Zhou; Olga Kholmanskikh; Danièle Godelaine; Charles De Smet; S Diane Hayward; François Fuks; Thierry Boon; Etienne De Plaen
MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription.
Nucleic acids research 2004;32(14):4340-50.
2004: Alexandra Vialle-Castellano; Sandra Laduron; Etienne De Plaen; Edgar Jost; Sophie Dupont; Geneviève Ameye; Lucienne Michaux; Pierre G Coulie; Daniel Olive; Thierry Boon; Nicolas van Baren
A gene expressed exclusively in acute B lymphoblastic leukemias.
Genomics 2004;83(1):85-94.
2003: Valérie Vantomme; Pascale Boël; Etienne De Plaen; Thierry Boon; Pierre van der Bruggen
A new tumor-specific antigenic peptide encoded by MAGE-6 is presented to cytolytic T lymphocytes by HLA-Cw16.
Cancer immunity 2003;3():17.
2003: T Kobayashi; Christophe Lonchay; Didier Colau; Nathalie Demotte; Thierry Boon; Pierre van der Bruggen
New MAGE-4 antigenic peptide recognized by cytolytic T lymphocytes on HLA-A1 tumor cells.
Tissue antigens 2003;62(5):426-32.
2003: VAIOS KARANIKAS; Christophe Lurquin; Didier Colau; Nicolas van Baren; Charles De Smet; Bernard Lethé; Thierry Connerotte; Véronique Corbière; Marie-Ange Demoitié; Danielle Liénard; Brigitte Dréno; Thierry Velu; Thierry Boon; Pierre G Coulie
Monoclonal anti-MAGE-3 CTL responses in melanoma patients displaying tumor regression after vaccination with a recombinant canarypox virus.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4898-904.
2003: Danièle Godelaine; Javier Carrasco; Sophie Lucas; VAIOS KARANIKAS; Beatrice Schuler-Thurner; Pierre G Coulie; Gerold Schuler; Thierry Boon; Aline Van Pel
Polyclonal CTL responses observed in melanoma patients vaccinated with dendritic cells pulsed with a MAGE-3.A1 peptide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4893-7.
2003: Catherine Uyttenhove; Luc Pilotte; Ivan Théate; Vincent Stroobant; Didier Colau; Nicolas Parmentier; Thierry Boon; Benoît J Van den Eynde
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.
Nature medicine 2003;9(10):1269-74.
2003: Yi Zhang; Pascal Chaux; Vincent Stroobant; Alexander M M Eggermont; Jurgen Corthals; Bernard Maillère; Kris Thielemans; Marie Marchand; Thierry Boon; Pierre van der Bruggen
A MAGE-3 peptide presented by HLA-DR1 to CD4+ T cells that were isolated from a melanoma patient vaccinated with a MAGE-3 protein.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):219-25.
2003: Axelle Loriot; Thierry Boon; Charles De Smet
Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia.
International journal of cancer. Journal international du cancer 2003;105(3):371-6.
2003: Thierry Boon; Nicolas van Baren
Immunosurveillance against cancer and immunotherapy--synergy or antagonism?
The New England journal of medicine 2003;348(3):252-4.
2003: Marie Marchand; Cornelis J A Punt; Steinar Aamdal; Bernard Escudier; Wim H J Kruit; U Keilholz; L Håkansson; Nicolas van Baren; Yves Humblet; P Mulders; M-F Avril; Alexander M M Eggermont; C Scheibenbogen; J Uiters; Jantien Wanders; M Delire; Thierry Boon; Gerrit Stoter
Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report.
European journal of cancer (Oxford, England : 1990) 2003;39(1):70-7.
2002: Pierre van der Bruggen; Yi Zhang; Pascal Chaux; Vincent Stroobant; Christophe Panichelli; Erwin S Schultz; Jacques Chapiro; Benoît J Van den Eynde; Francis Brasseur; Thierry Boon
Tumor-specific shared antigenic peptides recognized by human T cells.
Immunological reviews 2002;188():51-64.
2002: Pierre G Coulie; VAIOS KARANIKAS; Christophe Lurquin; Didier Colau; Thierry Connerotte; Takeshi Hanagiri; Aline Van Pel; Sophie Lucas; Danièle Godelaine; Christophe Lonchay; Marie Marchand; Nicolas van Baren; Thierry Boon
Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen.
Immunological reviews 2002;188():33-42.
2002: Francesca Schiavetti; Joëlle Thonnard; Didier Colau; Thierry Boon; Pierre G Coulie
A human endogenous retroviral sequence encoding an antigen recognized on melanoma by cytolytic T lymphocytes.
Cancer research 2002;62(19):5510-6.
2002: Janine Bilsborough; Catherine Uyttenhove; Didier Colau; Philippe Bousso; Claude Libert; Birgit Weynand; Thierry Boon; Benoît J Van den Eynde
TNF-mediated toxicity after massive induction of specific CD8+ T cells following immunization of mice with a tumor-specific peptide.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3053-60.
2002: J Bilsborough; C Panichelli; Marie-Thérèse Duffour; Guy Warnier; Christophe Lurquin; Erwin S Schultz; Kris Thielemans; Jurgen Corthals; Thierry Boon; Pierre van der Bruggen
A MAGE-3 peptide presented by HLA-B44 is also recognized by cytolytic T lymphocytes on HLA-B18.
Tissue antigens 2002;60(1):16-24.
2002: Nathalie Demotte; Didier Colau; Sabrina Ottaviani; Danièle Godelaine; Aline Van Pel; Thierry Boon; Pierre van der Bruggen
A reversible functional defect of CD8+ T lymphocytes involving loss of tetramer labeling.
European journal of immunology 2002;32(6):1688-97.
2002: Erwin S Schultz; Jacques Chapiro; Christophe Lurquin; Stéphane Claverol; Odile Burlet-Schiltz; Guy Warnier; Vincenzo Russo; Sandra Morel; Frédéric Lévy; Thierry Boon; Benoît J Van den Eynde; Pierre van der Bruggen
The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome.
The Journal of experimental medicine 2002;195(4):391-9.
2002: Nathalie Zammatteo; Laurence Lockman; Francis Brasseur; Etienne De Plaen; Christophe Lurquin; Pierre-Emmanuel Lobert; Sandrine Hamels; Thierry Boon; José Remacle
DNA microarray to monitor the expression of MAGE-A genes.
Clinical chemistry 2002;48(1):25-34.
2001: Pierre G Coulie; VAIOS KARANIKAS; Didier Colau; Christophe Lurquin; C Landry; Marie Marchand; Thierry Dorval; Vincent G Brichard; Thierry Boon
A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10290-5.
2001: Patrick Chomez; Olivier De Backer; M Bertrand; Etienne De Plaen; Thierry Boon; Sophie Lucas
An overview of the MAGE gene family with the identification of all human members of the family.
Cancer research 2001;61(14):5544-51.
2001: Pascal Chaux; Bernard Lethé; Jacques Van Snick; Jurgen Corthals; Erwin S Schultz; C L Cambiaso; Thierry Boon; Pierre van der Bruggen
A MAGE-1 peptide recognized on HLA-DR15 by CD4(+) T cells.
European journal of immunology 2001;31(6):1910-6.
2001: Michael Probst-Kepper; Vincent Stroobant; R Kridel; B Gaugler; C Landry; Francis Brasseur; J P Cosyns; Birgit Weynand; Thierry Boon; Benoît J Van den Eynde
An alternative open reading frame of the human macrophage colony-stimulating factor gene is independently translated and codes for an antigenic peptide of 14 amino acids recognized by tumor-infiltrating CD8 T lymphocytes.
The Journal of experimental medicine 2001;193(10):1189-98.
2001: VAIOS KARANIKAS; Didier Colau; Jean-Françis Baurain; R Chiari; Joëlle Thonnard; I Gutierrez-Roelens; C Goffinet; E V Van Schaftingen; P Weynants; Thierry Boon; Pierre G Coulie
High frequency of cytolytic T lymphocytes directed against a tumor-specific mutated antigen detectable with HLA tetramers in the blood of a lung carcinoma patient with long survival.
Cancer research 2001;61(9):3718-24.
2001: Erwin S Schultz; Y Zhang; R Knowles; J Tine; Catia Traversari; Thierry Boon; Pierre van der Bruggen
A MAGE-3 peptide recognized on HLA-B35 and HLA-A1 by cytolytic T lymphocytes.
Tissue antigens 2001;57(2):103-9.
2001: Aline Van Pel; Etienne De Plaen; Marie-Thérèse Duffour; Guy Warnier; Catherine Uyttenhove; Michel Perricaudet; Thierry Boon
Induction of cytolytic T lymphocytes by immunization of mice with an adenovirus containing a mouse homolog of the human MAGE-A genes.
Cancer immunology, immunotherapy : CII 2001;49(11):593-602.
2000: Erwin S Schultz; Bernard Lethé; C L Cambiaso; Jacques Van Snick; Pascal Chaux; Jurgen Corthals; Carlo Heirman; Kris Thielemans; Thierry Boon; Pierre van der Bruggen
A MAGE-A3 peptide presented by HLA-DP4 is recognized on tumor cells by CD4+ cytolytic T lymphocytes.
Cancer research 2000;60(22):6272-5.
2000: R Chiari; G Hames; Vincent Stroobant; Catherine Texier; Bernard Maillère; Thierry Boon; Pierre G Coulie
Identification of a tumor-specific shared antigen derived from an Eph receptor and presented to CD4 T cells on HLA class II molecules.
Cancer research 2000;60(17):4855-63.
2000: F Clotman; Olivier De Backer; Etienne De Plaen; Thierry Boon; J Picard
Cell- and stage-specific expression of mage genes during mouse spermatogenesis.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(8):696-9.
2000: V Martelange; Charles De Smet; Etienne De Plaen; Christophe Lurquin; Thierry Boon
Identification on a human sarcoma of two new genes with tumor-specific expression.
Cancer research 2000;60(14):3848-55.
2000: Sophie Lucas; Etienne De Plaen; Thierry Boon
MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression.
International journal of cancer. Journal international du cancer 2000;87(1):55-60.
2000: C Landry; Francis Brasseur; GC Spagnoli; E Marbaix; Thierry Boon; Pierre G Coulie; Danièle Godelaine
Monoclonal antibody 57B stains tumor tissues that express gene MAGE-A4.
International journal of cancer. Journal international du cancer 2000;86(6):835-41.
2000: Jean-Françis Baurain; Didier Colau; Nicolas van Baren; C Landry; V Martelange; M Vikkula; Thierry Boon; Pierre G Coulie
High frequency of autologous anti-melanoma CTL directed against an antigen generated by a point mutation in a new helicase gene.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):6057-66.
2000: L Heidecker; Francis Brasseur; Michael Probst-Kepper; M Guéguen; Thierry Boon; Benoît J Van den Eynde
Cytolytic T lymphocytes raised against a human bladder carcinoma recognize an antigen encoded by gene MAGE-A12.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):6041-5.
2000: L Q Huang; Thierry Boon; Aline Van Pel
Identification of a novel HLA-Cw*05 allele, Cw*0503.
Tissue antigens 2000;55(5):473-4.
2000: Sandra Morel; F Lévy; Odile Burlet-Schiltz; Francis Brasseur; Michael Probst-Kepper; Anne-Lise Peitrequin; Bernard Monsarrat; R Van Velthoven; J C Cerottini; Thierry Boon; Jean Edouard Gairin; Benoît J Van den Eynde
Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells.
Immunity 2000;12(1):107-17.
1999: Benoît J Van den Eynde; B Gaugler; Michael Probst-Kepper; L Michaux; O Devuyst; F Lorge; P Weynants; Thierry Boon
A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription.
The Journal of experimental medicine 1999;190(12):1793-800.
1999: A Serrano; Bernard Lethé; J M Delroisse; Christophe Lurquin; Etienne De Plaen; Francis Brasseur; Donata Rimoldi; Thierry Boon
Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries.
International journal of cancer. Journal international du cancer 1999;83(5):664-9.
1999: Charles De Smet; Christophe Lurquin; Bernard Lethé; V Martelange; Thierry Boon
DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter.
Molecular and cellular biology 1999;19(11):7327-35.
1999: Marie-Thérèse Duffour; Pascal Chaux; Christophe Lurquin; G Cornelis; Thierry Boon; Pierre van der Bruggen
A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes.
European journal of immunology 1999;29(10):3329-37.
1999: Pascal Chaux; Rosalie M Luiten; Nathalie Demotte; Valérie Vantomme; Vincent Stroobant; Catia Traversari; V Russo; Erwin S Schultz; G R Cornelis; Thierry Boon; Pierre van der Bruggen
Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2928-36.
1999: S Lucas; F Brasseur; Thierry Boon
A new MAGE gene with ubiquitous expression does not code for known MAGE antigens recognized by T cells.
Cancer research 1999;59(16):4100-3.
1999: Nicolas van Baren; Francis Brasseur; Danièle Godelaine; G Hames; A Ferrant; F Lehmann; M André; C Ravoet; C Doyen; GC Spagnoli; M Bakkus; Kris Thielemans; Thierry Boon
Genes encoding tumor-specific antigens are expressed in human myeloma cells.
Blood 1999;94(4):1156-64.
1999: Olivier De Backer; Karen C Arden; M Boretti; Valérie Vantomme; Charles De Smet; Suzanne Czekay; Carrie Viars; Etienne De Plaen; Francis Brasseur; Patrick Chomez; Benoît J Van den Eynde; Thierry Boon; Pierre van der Bruggen
Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.
Cancer research 1999;59(13):3157-65.
1999: S Silla; Francesca Fallarino; Thierry Boon; Catherine Uyttenhove
Enhancement by IL-12 of the cytolytic T lymphocyte (CTL) response of mice immunized with tumor-specific peptides in an adjuvant containing QS21 and MPL.
European cytokine network 1999;10(2):181-90.
1999: L Q Huang; Francis Brasseur; A Serrano; Etienne De Plaen; Pierre van der Bruggen; Thierry Boon; Aline Van Pel
Cytolytic T lymphocytes recognize an antigen encoded by MAGE-A10 on a human melanoma.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6849-54.
1999: Janine Bilsborough; Aline Van Pel; Catherine Uyttenhove; Thierry Boon; Benoît J Van den Eynde
Identification of a second major tumor-specific antigen recognized by CTLs on mouse mastocytoma P815.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3534-40.
1999: Pascal Chaux; Valérie Vantomme; Vincent Stroobant; Kris Thielemans; Jurgen Corthals; Rosalie M Luiten; Alexander M M Eggermont; Thierry Boon; Pierre van der Bruggen
Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes.
The Journal of experimental medicine 1999;189(5):767-78.
1999: Francesca Fallarino; Catherine Uyttenhove; Thierry Boon; Thomas F Gajewski
Improved efficacy of dendritic cell vaccines and successful immunization with tumor antigen peptide-pulsed peripheral blood mononuclear cells by coadministration of recombinant murine interleukin-12.
International journal of cancer. Journal international du cancer 1999;80(2):324-33.
1999: Marie Marchand; Nicolas van Baren; P Weynants; Vincent G Brichard; Brigitte Dréno; Marie-Hélène Tessier; E Rankin; G Parmiani; F Arienti; Yves Humblet; A Bourlond; R Vanwijck; D Liénard; Marc Beauduin; P Y Dietrich; V Russo; Joseph Kerger; G Masucci; E Jäger; J De Greve; J Atzpodien; Francis Brasseur; Pierre G Coulie; Pierre van der Bruggen; Thierry Boon
Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1.
International journal of cancer. Journal international du cancer 1999;80(2):219-30.
1999: Etienne De Plaen; Olivier De Backer; Danielle Arnaud; B Bonjean; Patrick Chomez; V Martelange; Philip Avner; Patricia Baldacci; Charles Babinet; S Y Hwang; B Knowles; Thierry Boon
A new family of mouse genes homologous to the human MAGE genes.
Genomics 1999;55(2):176-84.
1999: P Weynants; Joëlle Thonnard; Marie Marchand; M Delos; Thierry Boon; Pierre G Coulie
Derivation of tumor-specific cytolytic T-cell clones from two lung cancer patients with long survival.
American journal of respiratory and critical care medicine 1999;159(1):55-62.
1998: R Benitez; Danièle Godelaine; Miguel A Lopez-Nevot; Francis Brasseur; P Jiménez; M Marchand; Maria R Oliva; Nicolas van Baren; Teresa Cabrera; G Andry; C Landry; Francisco Ruiz-Cabello; Thierry Boon; Federico Garrido
Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides.
Tissue antigens 1998;52(6):520-9.
1998: D Brändle; Janine Bilsborough; T Rülicke; Catherine Uyttenhove; Thierry Boon; Benoît J Van den Eynde
The shared tumor-specific antigen encoded by mouse gene P1A is a target not only for cytolytic T lymphocytes but also for tumor rejection.
European journal of immunology 1998;28(12):4010-9.
1998: Nicolas van Baren; H Chambost; A Ferrant; Lucienne Michaux; H Ikeda; I Millard; Daniel Olive; Thierry Boon; Pierre G Coulie
PRAME, a gene encoding an antigen recognized on a human melanoma by cytolytic T cells, is expressed in acute leukaemia cells.
British journal of haematology 1998;102(5):1376-9.
1998: Pascal Chaux; Valérie Vantomme; P Coulie; Thierry Boon; Pierre van der Bruggen
Estimation of the frequencies of anti-MAGE-3 cytolytic T-lymphocyte precursors in blood from individuals without cancer.
International journal of cancer. Journal international du cancer 1998;77(4):538-42.
1998: M Guéguen; J J Patard; B Gaugler; Francis Brasseur; Jean-Christophe Renauld; Paul J Van Cangh; Thierry Boon; Benoît J Van den Eynde
An antigen recognized by autologous CTLs on a human bladder carcinoma.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6188-94.
1998: Bernard Lethé; Sophie Lucas; Lucienne Michaux; Charles De Smet; Danièle Godelaine; A Serrano; Etienne De Plaen; Thierry Boon
LAGE-1, a new gene with tumor specificity.
International journal of cancer. Journal international du cancer 1998;76(6):903-8.
1998: Sophie Lucas; Charles De Smet; Karen C Arden; Carrie Viars; Bernard Lethé; Christophe Lurquin; Thierry Boon
Identification of a new MAGE gene with tumor-specific expression by representational difference analysis.
Cancer research 1998;58(4):743-52.
1998: Joerg Schneider; Vincent G Brichard; Thierry Boon; Karl-Hermann Meyer zum Büschenfelde; Thomas Wölfel
Overlapping peptides of melanocyte differentiation antigen Melan-A/MART-1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1.
International journal of cancer. Journal international du cancer 1998;75(3):451-8.
1997: Charles De Smet; V Martelange; Sophie Lucas; Francis Brasseur; Christophe Lurquin; Thierry Boon
Identification of human testis-specific transcripts and analysis of their expression in tumor cells.
Biochemical and biophysical research communications 1997;241(3):653-7.
1997: Christophe Lurquin; Charles De Smet; Francis Brasseur; F Muscatelli; V Martelange; Etienne De Plaen; R Brasseur; Anthony P Monaco; Thierry Boon
Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins.
Genomics 1997;46(3):397-408.
1997: Francesca Fallarino; A Ashikari; Thierry Boon; Thomas F Gajewski
Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells.
International immunology 1997;9(9):1259-69.
1997: S Mandruzzato; Francis Brasseur; G Andry; Thierry Boon; Pierre van der Bruggen
A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.
The Journal of experimental medicine 1997;186(5):785-93.
1997: Bernard Lethé; Pierre van der Bruggen; Francis Brasseur; Thierry Boon
MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte.
Melanoma research 1997;7 Suppl 2():S83-8.
1997: Etienne De Plaen; Christophe Lurquin; Bernard Lethé; Pierre van der Bruggen; Vincent G Brichard; Jean-Christophe Renauld; Pierre G Coulie; Aline Van Pel; Thierry Boon
Identification of genes coding for tumor antigens recognized by cytolytic T lymphocytes.
Methods (San Diego, Calif.) 1997;12(2):125-42.
1997: Pierre G Coulie; Benoît J Van den Eynde; Pierre van der Bruggen; Aline Van Pel; Thierry Boon
Antigens recognized by T-lymphocytes on human tumours.
Biochemical Society transactions 1997;25(2):544-8.
1997: Etienne De Plaen; B Naerhuyzen; Charles De Smet; J P Szikora; Thierry Boon
Alternative promoters of gene MAGE4a.
Genomics 1997;40(2):305-13.
1997: H Ikeda; Bernard Lethé; F Lehmann; Nicolas van Baren; Jean-Françis Baurain; Charles De Smet; H Chambost; M Vitale; A Moretta; Thierry Boon; Pierre G Coulie
Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor.
Immunity 1997;6(2):199-208.
1997: Catherine Uyttenhove; C Godfraind; Bernard Lethé; A Amar-Costesec; Jean-Christophe Renauld; Thomas F Gajewski; Marie-Thérèse Duffour; Guy Warnier; Thierry Boon; Benoît J Van den Eynde
The expression of mouse gene P1A in testis does not prevent safe induction of cytolytic T cells against a P1A-encoded tumor antigen.
International journal of cancer. Journal international du cancer 1997;70(3):349-56.
1997: Charles De Smet; Christophe Lurquin; Etienne De Plaen; Francis Brasseur; H Zarour; Olivier De Backer; Pierre G Coulie; Thierry Boon
Genes coding for melanoma antigens recognised by cytolytic T lymphocytes.
Eye (London, England) 1997;11 ( Pt 2)():243-8.
1996: Guy Warnier; Marie-Thérèse Duffour; Catherine Uyttenhove; Thomas F Gajewski; Christophe Lurquin; Hedi Haddada; Michel Perricaudet; Thierry Boon
Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A.
International journal of cancer. Journal international du cancer 1996;67(2):303-10.
1996: Charles De Smet; Olivier De Backer; I Faraoni; Christophe Lurquin; Francis Brasseur; Thierry Boon
The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7149-53.
1996: H Zarour; Charles De Smet; F Lehmann; M Marchand; Bernard Lethé; P Romero; Thierry Boon; J C Renauld
The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100.
The Journal of investigative dermatology 1996;107(1):63-7.
1996: K A Mulcahy; Donata Rimoldi; Francis Brasseur; S Rodgers; D Liénard; M Marchand; I G Rennie; Anna K Murray; C A McIntyre; K E Platts; S Leyvraz; Thierry Boon; Robert C Rees
Infrequent expression of the MAGE gene family in uveal melanomas.
International journal of cancer. Journal international du cancer 1996;66(6):738-42.
1996: D Brändle; Francis Brasseur; P Weynants; Thierry Boon; Benoît J Van den Eynde
A mutated HLA-A2 molecule recognized by autologous cytotoxic T lymphocytes on a human renal cell carcinoma.
The Journal of experimental medicine 1996;183(6):2501-8.
1996: Thomas F Gajewski; Francesca Fallarino; Catherine Uyttenhove; Thierry Boon
Tumor rejection requires a CTLA4 ligand provided by the host or expressed on the tumor: superiority of B7-1 over B7-2 for active tumor immunization.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2909-17.
1996: Thierry Boon; Pierre van der Bruggen
Human tumor antigens recognized by T lymphocytes.
The Journal of experimental medicine 1996;183(3):725-9.
1996: Y Guilloux; S Lucas; Vincent G Brichard; Aline Van Pel; C Viret; Etienne De Plaen; Francis Brasseur; Bernard Lethé; Francine Jotereau; Thierry Boon
A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene.
The Journal of experimental medicine 1996;183(3):1173-83.
1996: JC Skipper; Ronald Hendrickson; PH Gulden; Vincent G Brichard; Aline Van Pel; Y Chen; Jeffrey Shabanowitz; T Wolfel; Craig L Slingluff; Thierry Boon; Donald F Hunt; Victor H Engelhard
An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins.
The Journal of experimental medicine 1996;183(2):527-34.
1996: Francesca Fallarino; Catherine Uyttenhove; Thierry Boon; Thomas F Gajewski
Endogenous IL-12 is necessary for rejection of P815 tumor variants in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1095-100.
1996: B Gaugler; Nathalie Brouwenstijn; Valérie Vantomme; J P Szikora; CW van der Spek; J J Patard; Thierry Boon; Peter I Schrier; Benoît J Van den Eynde
A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma.
Immunogenetics 1996;44(5):323-30.
1996: J Herman; Pierre van der Bruggen; I F Luescher; S Mandruzzato; Pedro Romero; Joëlle Thonnard; Katharina Fleischhauer; Thierry Boon; Pierre G Coulie
A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3.
Immunogenetics 1996;43(6):377-83.
1996: Vincent G Brichard; J Herman; Aline Van Pel; C Wildmann; B Gaugler; Thomas Wölfel; Thierry Boon; Bernard Lethé
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
European journal of immunology 1996;26(1):224-30.
1996: Patrick Chomez; R Williams; Olivier De Backer; Thierry Boon; B Vennström
The SMAGE gene family is expressed in post-meiotic spermatids during mouse germ cell differentiation.
Immunogenetics 1996;43(1-2):97-100.
1995: Ursula Grohmann; Roberta Bianchi; Maria C Fioretti; Francesca Fallarino; L Binaglia; Catherine Uyttenhove; Aline Van Pel; Thierry Boon; Paolo Puccetti
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide.
European journal of immunology 1995;25(10):2797-802.
1995: Benoît J Van den Eynde; O Peeters; Olivier De Backer; B Gaugler; S Lucas; Thierry Boon
A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.
The Journal of experimental medicine 1995;182(3):689-98.
1995: Pierre G Coulie; F Lehmann; Bernard Lethé; J Herman; Christophe Lurquin; M Andrawiss; Thierry Boon
A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7976-80.
1995: Benoît J Van den Eynde; B Gaugler; Pierre van der Bruggen; Pierre G Coulie; Vincent G Brichard; Thierry Boon
Human tumour antigens recognized by T-cells: perspectives for new cancer vaccines.
Biochemical Society transactions 1995;23(3):681-6.
1995: Olivier De Backer; A M Verheyden; B Martin; Danièle Godelaine; Etienne De Plaen; R Brasseur; Philip Avner; Thierry Boon
Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.
Genomics 1995;28(1):74-83.
1995: A Van Pel; Pierre van der Bruggen; P G Coulie; Vincent G Brichard; Bernard Lethé; Benoît J Van den Eynde; Catherine Uyttenhove; J C Renauld; Thierry Boon
Genes coding for tumor antigens recognized by cytolytic T lymphocytes.
Immunological reviews 1995;145():229-50.
1995: Thomas F Gajewski; J C Renauld; Aline Van Pel; Thierry Boon
Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5637-48.
1995: Vincent G Brichard; Guy Warnier; Aline Van Pel; G Morlighem; S Lucas; Thierry Boon
Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815.
European journal of immunology 1995;25(3):664-71.
1995: P Boël; C Wildmann; M L Sensi; R Brasseur; J C Renauld; Pierre G Coulie; Thierry Boon; Pierre van der Bruggen
BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes.
Immunity 1995;2(2):167-75.
1995: F Lehmann; M Marchand; P Hainaut; P Pouillart; X Sastre; H Ikeda; Thierry Boon; Pierre G Coulie
Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection.
European journal of immunology 1995;25(2):340-7.
1995: Charles De Smet; S J Courtois; I Faraoni; Christophe Lurquin; J P Szikora; Olivier De Backer; Thierry Boon
Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene.
Immunogenetics 1995;42(4):282-90.
1994: Pierre van der Bruggen; J Bastin; Thomas F Gajewski; Pierre G Coulie; P Boël; Charles De Smet; Catia Traversari; A Townsend; Thierry Boon
A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.
European journal of immunology 1994;24(12):3038-43.
1994: V de Bergeyck; Etienne De Plaen; Patrick Chomez; Thierry Boon; Aline Van Pel
An intracisternal A-particle sequence codes for an antigen recognized by syngeneic cytolytic T lymphocytes on a mouse spontaneous leukemia.
European journal of immunology 1994;24(9):2203-12.
1994: Pierre van der Bruggen; J P Szikora; P Boël; C Wildmann; M Somville; M Sensi; Thierry Boon
Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601.
European journal of immunology 1994;24(9):2134-40.
1994: Pierre G Coulie; Vincent G Brichard; Aline Van Pel; Thomas Wölfel; J Schneider; Catia Traversari; S Mattei; Etienne De Plaen; Christophe Lurquin; J P Szikora; J C Renauld; Thierry Boon
A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
The Journal of experimental medicine 1994;180(1):35-42.
1994: Paolo Puccetti; Roberta Bianchi; Maria C Fioretti; Emira Ayroldi; Catherine Uyttenhove; Aline Van Pel; Thierry Boon; Ursula Grohmann
Use of a skin test assay to determine tumor-specific CD8+ T cell reactivity.
European journal of immunology 1994;24(6):1446-52.
1994: P Weynants; Bernard Lethé; Francis Brasseur; M Marchand; Thierry Boon
Expression of mage genes by non-small-cell lung carcinomas.
International journal of cancer. Journal international du cancer 1994;56(6):826-9.
1994: Thomas Wölfel; Aline Van Pel; Vincent G Brichard; J Schneider; Barbara Seliger; K H Meyer zum Büschenfelde; Thierry Boon
Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes.
European journal of immunology 1994;24(3):759-64.
1994: B Gaugler; Benoît J Van den Eynde; Pierre van der Bruggen; P Romero; José Gaforio; Etienne De Plaen; Bernard Lethé; Francis Brasseur; Thierry Boon
Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.
The Journal of experimental medicine 1994;179(3):921-30.
1994: Charles De Smet; Christophe Lurquin; Pierre van der Bruggen; Etienne De Plaen; Francis Brasseur; Thierry Boon
Sequence and expression pattern of the human MAGE2 gene.
Immunogenetics 1994;39(2):121-9.
1994: Thierry Boon; Pierre G Coulie; M Marchand; P Weynants; Thomas Wölfel; Vincent G Brichard
Genes coding for tumor rejection antigens: perspectives for specific immunotherapy.
Important advances in oncology 1994;():53-69.
1994: Thierry Boon; Benoît J Van den Eynde; H Hirsch; C Moroni; Etienne De Plaen; Pierre van der Bruggen; Charles De Smet; Christophe Lurquin; J P Szikora; Olivier De Backer
Genes coding for tumor-specific rejection antigens.
Cold Spring Harbor symposia on quantitative biology 1994;59():617-22.
1993: Thomas Wölfel; M Hauer; E Klehmann; Vincent G Brichard; B Ackermann; Alexander Knuth; Thierry Boon; K H Meyer Zum Büschenfelde
Analysis of antigens recognized on human melanoma cells by A2-restricted cytolytic T lymphocytes (CTL).
International journal of cancer. Journal international du cancer 1993;55(2):237-44.
1993: Pierre G Coulie; P Weynants; C Muller; F Lehmann; J Herman; Jean-Françis Baurain; Thierry Boon
Genes coding for antigens recognized on human tumors by autologous cytolytic T lymphocytes.
Annals of the New York Academy of Sciences 1993;690():113-9.
1993: Vincent G Brichard; Aline Van Pel; Thomas Wölfel; C Wölfel; Etienne De Plaen; Bernard Lethé; Pierre G Coulie; Thierry Boon
The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.
The Journal of experimental medicine 1993;178(2):489-95.
1993: Pierre G Coulie; P Weynants; F Lehmann; J Herman; Vincent G Brichard; Thomas Wölfel; Aline Van Pel; Etienne De Plaen; Francis Brasseur; Thierry Boon
Genes coding for tumor antigens recognized by human cytolytic T lymphocytes.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(2):104-9.
1993: Thierry Boon
Tumor antigens recognized by cytolytic T lymphocytes: present perspectives for specific immunotherapy.
International journal of cancer. Journal international du cancer 1993;54(2):177-80.
1993: J P Szikora; Aline Van Pel; Thierry Boon
Tum- mutation P35B generates the MHC-binding site of a new antigenic peptide.
Immunogenetics 1993;37(2):135-8.
1992: Francis Brasseur; M Marchand; R Vanwijck; M Hérin; Bernard Lethé; Patrick Chomez; Thierry Boon
Human gene MAGE-1, which codes for a tumor-rejection antigen, is expressed by some breast tumors.
International journal of cancer. Journal international du cancer 1992;52(5):839-41.
1992: Catia Traversari; Pierre van der Bruggen; I F Luescher; Christophe Lurquin; Patrick Chomez; Aline Van Pel; Etienne De Plaen; A Amar-Costesec; Thierry Boon
A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.
The Journal of experimental medicine 1992;176(5):1453-7.
1992: Bernard Lethé; Benoît J Van den Eynde; Aline Van Pel; G Corradin; Thierry Boon
Mouse tumor rejection antigens P815A and P815B: two epitopes carried by a single peptide.
European journal of immunology 1992;22(9):2283-8.
1992: Pierre G Coulie; M Somville; F Lehmann; P Hainaut; Francis Brasseur; R Devos; Thierry Boon
Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells.
International journal of cancer. Journal international du cancer 1992;50(2):289-97.
1992: Thierry Boon
Toward a genetic analysis of tumor rejection antigens.
Advances in cancer research 1992;58():177-210.
1992: Patrick Chomez; Etienne De Plaen; Aline Van Pel; Charles De Smet; J P Szikora; Christophe Lurquin; A M Lebacq-Verheyden; Thierry Boon
Efficient expression of tum- antigen P91A by transfected subgenic fragments.
Immunogenetics 1992;35(4):241-52.
1992: Catia Traversari; Pierre van der Bruggen; Benoît J Van den Eynde; P Hainaut; C Lemoine; N Ohta; Lloyd J Old; Thierry Boon
Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes.
Immunogenetics 1992;35(3):145-52.
1992: Thierry Boon; Etienne De Plaen; Christophe Lurquin; Benoît J Van den Eynde; Pierre van der Bruggen; Catia Traversari; A Amar-Costesec; Aline Van Pel
Identification of tumour rejection antigens recognized by T lymphocytes.
Cancer surveys 1992;13():23-37.
1991: Aline Van Pel; Guy Warnier; Benoît J Van den Eynde; Bernard Lethé; Christophe Lurquin; Thierry Boon
Tum- antigens, TSTA, and T cell immune surveillance.
Annals of the New York Academy of Sciences 1991;636():43-51.
1991: Pierre van der Bruggen; Catia Traversari; Patrick Chomez; Christophe Lurquin; Etienne De Plaen; Benoît J Van den Eynde; A Knuth; Thierry Boon
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma.
Science (New York, N.Y.) 1991;254(5038):1643-7.
1991: Benoît J Van den Eynde; Bernard Lethé; Aline Van Pel; Etienne De Plaen; Thierry Boon
The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice.
The Journal of experimental medicine 1991;173(6):1373-84.
1990: G Degiovanni; P Hainaut; T Lahaye; P Weynants; Thierry Boon
Antigens recognized on a melanoma cell line by autologous cytolytic T lymphocytes are also expressed on freshly collected tumor cells.
European journal of immunology 1990;20(8):1865-8.
1990: C Sibille; Patrick Chomez; C Wildmann; Aline Van Pel; Etienne De Plaen; J L Maryanski; V de Bergeyck; Thierry Boon
Structure of the gene of tum- transplantation antigen P198: a point mutation generates a new antigenic peptide.
The Journal of experimental medicine 1990;172(1):35-45.
1990: J P Szikora; Aline Van Pel; Vincent G Brichard; M André; Nicolas van Baren; P Henry; Etienne De Plaen; Thierry Boon
Structure of the gene of tum- transplantation antigen P35B: presence of a point mutation in the antigenic allele.
The EMBO journal 1990;9(4):1041-50.
1989: Benoît J Van den Eynde; P Hainaut; M Hérin; A Knuth; C Lemoine; P Weynants; Pierre van der Bruggen; R Fauchet; Thierry Boon
Presence on a human melanoma of multiple antigens recognized by autologous CTL.
International journal of cancer. Journal international du cancer 1989;44(4):634-40.
1989: Thierry Boon; Aline Van Pel; Etienne De Plaen
Tum- transplantation antigens, point mutations, and antigenic peptides: a model for tumor-specific transplantation antigens?
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1989;1(1):25-8.
1989: Christophe Lurquin; Aline Van Pel; B Mariamé; Etienne De Plaen; J P Szikora; C Janssens; M J Reddehase; J Lejeune; Thierry Boon
Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cells.
Cell 1989;58(2):293-303.
1989: Thierry Boon; J P Szikora; Etienne De Plaen; Thomas Wölfel; Aline Van Pel
Cloning and characterization of genes coding for tum- transplantation antigens.
Journal of autoimmunity 1989;2 Suppl():109-14.
1989: Alexander Knuth; Thomas Wölfel; E Klehmann; Thierry Boon; K H Meyer zum Büschenfelde
Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2804-8.
1989: Thierry Boon; Aline Van Pel
T cell-recognized antigenic peptides derived from the cellular genome are not protein degradation products but can be generated directly by transcription and translation of short subgenic regions. A hypothesis.
Immunogenetics 1989;29(2):75-9.
1989: Thierry Boon; Aline Van Pel; Etienne De Plaen; Patrick Chomez; Christophe Lurquin; J P Szikora; C Sibille; B Mariamé; Benoît J Van den Eynde; Bernard Lethé
Genes coding for T-cell-defined tum transplantation antigens: point mutations, antigenic peptides, and subgenic expression.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():587-96.
1988: G Degiovanni; T Lahaye; M Hérin; P Hainaut; Thierry Boon
Antigenic heterogeneity of a human melanoma tumor detected by autologous CTL clones.
European journal of immunology 1988;18(5):671-6.
1988: Etienne De Plaen; Christophe Lurquin; Aline Van Pel; B Mariamé; J P Szikora; Thomas Wölfel; C Sibille; Patrick Chomez; Thierry Boon
Immunogenic (tum-) variants of mouse tumor P815: cloning of the gene of tum- antigen P91A and identification of the tum- mutation.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2274-8.
1988: J Van Snick; S Cayphas; J P Szikora; J C Renauld; E Van Roost; Thierry Boon; Richard J Simpson
cDNA cloning of murine interleukin-HP1: homology with human interleukin 6.
European journal of immunology 1988;18(2):193-7.
1988: Aline Van Pel; Etienne De Plaen; Christophe Lurquin; Benoît J Van den Eynde; Bernard Lethé; P Hainaut; C Lemoine; Thierry Boon
Identification of genes encoding T cell defined tum- antigens.
Princess Takamatsu symposia 1988;19():255-63.
1987: M Hérin; C Lemoine; P Weynants; F Vessière; Aline Van Pel; A Knuth; R Devos; Thierry Boon
Production of stable cytolytic T-cell clones directed against autologous human melanoma.
International journal of cancer. Journal international du cancer 1987;39(3):390-6.
1986: Thierry Boon; Aline Van Pel; Etienne De Plaen; F Vessière
Mutagen-induced antigenic variants of tumor cells.
Symposium on Fundamental Cancer Research 1986;38():139-48.
1983: Aline Van Pel; F Vessière; Thierry Boon
Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis.
The Journal of experimental medicine 1983;157(6):1992-2001.
1982: F Vessière; M Georlette; Guy Warnier; J C Leclerc; Aline Van Pel; Thierry Boon
Immunogenic variants obtained by mutagenesis of mouse Lewis lung carcinoma. Recognition of variant-specific antigens by cytolytic T lymphocytes.
European journal of cancer & clinical oncology 1982;18(9):867-74.