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Philippa Talmud

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Ntalla Ioanna; Dedoussis George; Yannakoulia Mary; Smart Melissa C; Louizou Eirini; Sakka Sophia D; Papoutsakis Constantina; Talmud Philippa J
ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity.
Talmud Philippa J; Drenos Fotios; Shah Sonia; Shah Tina; Palmen Jutta; Verzilli Claudio; Gaunt Tom R; Pallas Jacky; Lovering Ruth; Li Kawah; Casas Juan Pablo; Sofat Reecha; Kumari Meena; Rodriguez Santiago; Johnson Toby; Newhouse Stephen J; Dominiczak Anna; Samani Nilesh J; Caulfield Mark; Sever Peter; Stanton Alice; Shields Denis C;
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Lovering Ruth C; Dimmer Emily C; Talmud Philippa J
Improvements to cardiovascular gene ontology.

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All Publications

2009: Ntalla Ioanna; Dedoussis George; Yannakoulia Mary; Smart Melissa C; Louizou Eirini; Sakka Sophia D; Papoutsakis Constantina; Talmud Philippa J
ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity.
European journal of nutrition 2009;48(8):493-7.
2009: Talmud Philippa J; Drenos Fotios; Shah Sonia; Shah Tina; Palmen Jutta; Verzilli Claudio; Gaunt Tom R; Pallas Jacky; Lovering Ruth; Li Kawah; Casas Juan Pablo; Sofat Reecha; Kumari Meena; Rodriguez Santiago; Johnson Toby; Newhouse Stephen J; Dominiczak Anna; Samani Nilesh J; Caulfield Mark; Sever Peter; Stanton Alice; Shields Denis C;
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics 2009;85(5):628-42.
2009: Lovering Ruth C; Dimmer Emily C; Talmud Philippa J
Improvements to cardiovascular gene ontology.
Atherosclerosis 2009;205(1):9-14.
2009: Drenos Fotios; Talmud Philippa J; Casas Juan P; Smeeth Liam; Palmen Jutta; Humphries Steve E; Hingorani Aroon D
Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
Human molecular genetics 2009;18(12):2305-16.
2009: Laatsch Alexander; Merkel Martin; Talmud Philippa J; Grewal Thomas; Beisiegel Ulrike; Heeren Joerg
Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance.
Atherosclerosis 2009;204(1):105-11.
2009: Kotronen Anna; Yki-Järvinen Hannele; Aminoff Anna; Bergholm Robert; Pietiläinen Kirsi H; Westerbacka Jukka; Talmud Philippa J; Humphries Steve E; Hamsten Anders; Isomaa Bo; Groop Leif; Orho-Melander Marju; Ehrenborg Ewa; Fisher Rachel M
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.
European journal of endocrinology / European Federation of Endocrine Societies 2009;160(4):593-602.
2009: Hingorani Aroon D; Shah Tina; Casas Juan P; Humphries Steve E; Talmud Philippa J
C-reactive protein and coronary heart disease: predictive test or therapeutic target?
Clinical chemistry 2009;55(2):239-55.
2008: Talmud Philippa J; Smart Melissa; Presswood Edward; Cooper Jackie A; Nicaud Viviane; Drenos Fotios; Palmen Jutta; Marmot Michael G; Boekholdt S Matthijs; Wareham Nicholas J; Khaw Kay-Tee; Kumari Meena; Humphries Steve E;
ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(12):2319-25.
2008: Dorfmeister B; Zeng W W; Dichlberger A; Nilsson S K; Schaap F G; Hubacek J A; Merkel M; Cooper J A; Lookene A; Putt W; Whittall R; Lee P J; Lins L; Delsaux N; Nierman M; Kuivenhoven J A; Kastelein J J P; Vrablik M; Olivecrona G; Schneider W J; Heeren J; Humphries S E; Talmud P J
Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1866-71.
2008: Salpea Klelia D; Nicaud Viviane; Tiret Laurence; Talmud Philippa J; Humphries Steve E;
The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II.
Journal of molecular medicine (Berlin, Germany) 2008;86(7):815-24.
2008: Palmen Jutta; Smith Andrew J P; Dorfmeister Birgit; Putt Wendy; Humphries Steve E; Talmud Philippa J
The functional interaction on in vitro gene expression of APOA5 SNPs, defining haplotype APOA52, and their paradoxical association with plasma triglyceride but not plasma apoAV levels.
Biochimica et biophysica acta 2008;1782(7-8):447-52.
2008: Lovering Ruth C; Dimmer Emily; Khodiyar Varsha K; Barrell Daniel G; Scambler Peter; Hubank Mike; Apweiler Rolf; Talmud Philippa J
Cardiovascular GO annotation initiative year 1 report: why cardiovascular GO?
Proteomics 2008;8(10):1950-3.
2008: Humphries Steve E; Yiannakouris Nikos; Talmud Philippa J
Cardiovascular disease risk prediction using genetic information (gene scores): is it really informative?
Current opinion in lipidology 2008;19(2):128-32.
2008: Talmud Philippa J; Cooper Jackie A; Palmen Jutta; Lovering Ruth; Drenos Fotios; Hingorani Aroon D; Humphries Steve E
Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.
Clinical chemistry 2008;54(3):467-74.
2008: Hubacek Jaroslav A; Wang Wu-Wei; Skodová Zdena; Adámková Vera; Vráblík Michal; Horínek Ales; Stulc Tomás; Ceska Richard; Talmud Philippa J
APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(6):773-7.
2007: Talmud Philippa J
Rare APOA5 mutations--clinical consequences, metabolic and functional effects: an ENID review.
Atherosclerosis 2007;194(2):287-92.
2007: Wootton Peter T E; Arora Nupur L; Drenos Fotios; Thompson Simon R; Cooper Jackie A; Stephens Jeffrey W; Hurel Steven J; Hurt-Camejo Eva; Wiklund Olov; Humphries Steve E; Talmud Philippa J
Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study.
Human molecular genetics 2007;16(12):1437-44.
2007: Talmud Philippa J; Flavell David M; Alfakih Khaled; Cooper Jackie A; Balmforth Anthony J; Sivananthan Mohan; Montgomery Hugh E; Hall Alistair S; Humphries Steve E
The lipoprotein lipase gene serine 447 stop variant influences hypertension-induced left ventricular hypertrophy and risk of coronary heart disease.
Clinical science (London, England : 1979) 2007;112(12):617-24.
2007: Wong Wai-Man R; Gerry Andrew B; Putt Wendy; Roberts Jane L; Weinberg Richard B; Humphries Steve E; Leake David S; Talmud Philippa J
Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation.
Atherosclerosis 2007;192(2):266-74.
2007: Dorfmeister Birgit; Cooper Jackie A; Stephens Jeffrey W; Ireland Helen; Hurel Steven J; Humphries Steve E; Talmud Philippa J
The effect of APOA5 and APOC3 variants on lipid parameters in European Whites, Indian Asians and Afro-Caribbeans with type 2 diabetes.
Biochimica et biophysica acta 2007;1772(3):355-63.
2007: Talmud Philippa J
Gene-environment interaction and its impact on coronary heart disease risk.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2007;17(2):148-52.
2007: Wootton Peter T E; Flavell David M; Montgomery Hugh E; World Mike; Humphries Steve E; Talmud Philippa J
Lipoprotein-associated phospholipase A2 A379V variant is associated with body composition changes in response to exercise training.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2007;17(1):24-31.
2007: van der Vleuten Gerly M; Isaacs Aaron; Zeng Wu-Wei; ter Avest Ewoud; Talmud Philippa J; Dallinga-Thie Geesje M; van Duijn Cornelia M; Stalenhoef Anton F H; de Graaf Jacqueline
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia.
Biochimica et biophysica acta 2007;1772(1):81-8.
2007: Humphries Steve E; Cooper Jackie A; Talmud Philippa J; Miller George J
Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men.
Clinical chemistry 2007;53(1):8-16.
2006: Humphries Steve E; Gable David; Cooper Jackie A; Ireland Helen; Stephens Jeffrey W; Hurel Steven J; Li Ka Wah; Palmen Jutta; Miller Michelle A; Cappuccio Francesco P; Elkeles Robert; Godsland Ian; Miller George J; Talmud Philippa J
Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women.
Journal of molecular medicine (Berlin, Germany) 2006;84(12):1005-14.
2006: Wootton P T E; Stephens J W; Hurel S J; Durand H; Cooper J; Ninio E; Humphries S E; Talmud P J
Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus.
Atherosclerosis 2006;189(1):149-56.
2006: Talmud P J; Cooper J A; Hattori H; Miller I P; Miller G J; Humphries S E
The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: prospective risk of type 2 diabetes. Results from the Northwick Park Heart Study II.
Diabetologia 2006;49(10):2337-40.
2006: Schaap Frank G; Nierman Melchior C; Berbée Jimmy F P; Hattori Hiroaki; Talmud Philippa J; Vaessen Stefan F C; Rensen Patrick C N; Chamuleau Robert A F M; Kuivenhoven Jan Albert; Groen Albert K
Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia.
Journal of lipid research 2006;47(10):2333-9.
2006: Vaessen Stefan F C; Schaap Frank G; Kuivenhoven Jan-Albert; Groen Albert K; Hutten Barbara A; Boekholdt S Matthijs; Hattori Hiroaki; Sandhu Manjinder S; Bingham Sheila A; Luben Robert; Palmen Jutta A; Wareham Nicholas J; Humphries Steve E; Kastelein John J P; Talmud Philippa J; Khaw Kay-Tee
Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.
Journal of lipid research 2006;47(9):2064-70.
2006: Flavell David M; Wootton Peter T E; Myerson Saul G; World Michael J; Pennell Dudley J; Humphries Steve E; Talmud Philippa J; Montgomery Hugh E
Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth.
Journal of molecular medicine (Berlin, Germany) 2006;84(2):126-31.
2006: Wootton Peter T E; Drenos Fotios; Cooper Jackie A; Thompson Simon R; Stephens Jeffrey W; Hurt-Camejo Eva; Wiklund Olov; Humphries Steve E; Talmud Philippa J
Tagging-SNP haplotype analysis of the secretory PLA2IIa gene PLA2G2A shows strong association with serum levels of sPLA2IIa: results from the UDACS study.
Human molecular genetics 2006;15(2):355-61.
2005: Talmud P J; Stephens J W; Hawe E; Demissie S; Cupples L A; Hurel S J; Humphries S E; Ordovas J M
The significant increase in cardiovascular disease risk in APOEepsilon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4.
Annals of human genetics 2005;69(Pt 6):613-22.
2005: Talmud Philippa J; Palmen Jutta; Putt Wendy; Lins Laurence; Humphries Steve E
Determination of the functionality of common APOA5 polymorphisms.
The Journal of biological chemistry 2005;280(31):28215-20.
2005: Waterworth Dawn M; Jansen Hans; Nicaud Viviane; Humphries Steve E; Talmud Philippa J;
Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.
Biochimica et biophysica acta 2005;1740(3):375-81.
2005: Younis Jenan; Cooper Jackie A; Miller George J; Humphries Steve E; Talmud Philippa J
Genetic variation in alcohol dehydrogenase 1C and the beneficial effect of alcohol intake on coronary heart disease risk in the Second Northwick Park Heart Study.
Atherosclerosis 2005;180(2):225-32.
2005: Talmud Philippa J; Palmen Jutta; Wolf Anna M; Beisiegel Ulrike
Investigation into the role of the hormone sensitive lipase -60C>G promoter variant in morbid obesity.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2005;15(1):31-5.
2005: Elrayess Mohamed A; Talmud Philippa J
Platelet endothelial cell adhesion molecule-1 (PECAM-1) & coronary heart disease.
The Indian journal of medical research 2005;121(2):77-9.
2004: Foucher Christelle; Rattier Stephanie; Flavell David M; Talmud Philippa J; Humphries Steve E; Kastelein John J P; Ayyobi Amir; Pimstone Simon; Frohlich Jiri; Ansquer Jean-Claude; Steiner George;
Response to micronized fenofibrate treatment is associated with the peroxisome-proliferator-activated receptors alpha G/C intron7 polymorphism in subjects with type 2 diabetes.
Pharmacogenetics 2004;14(12):823-9.
2004: Talmud Philippa J; Lewis Sarah J; Hawe Emma; Martin Steve; Acharya Jayshree; Marmot Michael G; Humphries Steve E; Brunner Eric J
No APOEepsilon4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II study.
Atherosclerosis 2004;177(1):105-12.
2004: Wong Wai-Man R; Stephens Jeffrey W; Acharya Jayshree; Hurel Steven J; Humphries Steve E; Talmud Philippa J
The APOA4 T347S variant is associated with reduced plasma TAOS in subjects with diabetes mellitus and cardiovascular disease.
Journal of lipid research 2004;45(8):1565-71.
2004: Putt Wendy; Palmen Jutta; Nicaud Viviane; Tregouet David-Alexandre; Tahri-Daizadeh Nadia; Flavell David M; Humphries Steve E; Talmud Philippa J;
Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.
Human molecular genetics 2004;13(15):1587-97.
2004: Austin M A; Zhang C; Humphries S E; Chandler W L; Talmud P J; Edwards K L; Leonetti D L; McNeely M J; Fujimoto W Y
Heritability of C-reactive protein and association with apolipoprotein E genotypes in Japanese Americans.
Annals of human genetics 2004;68(Pt 3):179-88.
2004: Austin Melissa A; Edwards Karen L; McNeely Marguerite J; Chandler Wayne L; Leonetti Donna L; Talmud Philippa J; Humphries Steve E; Fujimoto Wilfred Y
Heritability of multivariate factors of the metabolic syndrome in nondiabetic Japanese americans.
Diabetes 2004;53(4):1166-9.
2004: Talmud Philippa J; Martin Steve; Taskinen Marja-Riitta; Frick M Heikki; Nieminen Markku S; Kesäniemi Y Antero; Pasternack Amos; Humphries Steve E; Syvänne Mikko
APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.
Journal of lipid research 2004;45(4):750-6.
2004: Humphries Steve E; Ridker Paul M; Talmud Philippa J
Genetic testing for cardiovascular disease susceptibility: a useful clinical management tool or possible misinformation?
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):628-36.
2004: Talmud Philippa J
How to identify gene-environment interactions in a multifactorial disease: CHD as an example.
The Proceedings of the Nutrition Society 2004;63(1):5-10.
2004: Austin Melissa A; Talmud Philippa J; Farin Federico M; Nickerson Deborah A; Edwards Karen L; Leonetti Donna; McNeely Marguerite J; Viernes Hannah-Malia; Humphries Steve E; Fujimoto Wilfred Y
Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans.
Biochimica et biophysica acta 2004;1688(1):1-9.
2004: Talmud Philippa J; Stephens Jeffrey W
Lipoprotein lipase gene variants and the effect of environmental factors on cardiovascular disease risk.
Diabetes, obesity & metabolism 2004;6(1):1-7.
2004: Talmud Philippa J; Humphries Steve E
Gene: environment interactions and coronary heart disease risk.
World review of nutrition and dietetics 2004;93():29-40.
2004: Chen Xiao-he; Rodríguez Santiago; Hawe Emma; Talmud Philippa J; Miller George J; Underhill Peter; Humphries Stephen E; Day Ian N M
Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses.
Human heredity 2004;57(3):142-55.
2003: Robertson Kirsty S; Hawe Emma; Miller George J; Talmud Philippa J; Humphries Steve E;
Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II.
Biochimica et biophysica acta 2003;1639(3):203-12.
2003: Hubacek Jaroslav A; Pitha Jan; Skodová Zdena; Poledne Rudolf; Lánská Vera; Waterworth Dawn M; Humphries Steve E; Talmud Philippa J;
Polymorphisms in CYP-7A1, not APOE, influence the change in plasma lipids in response to population dietary change in an 8 year follow-up; results from the Czech MONICA study.
Clinical biochemistry 2003;36(4):263-7.
2003: Abuzeid A M; Hawe E; Humphries S E; Talmud Philippa J;
Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe.
Atherosclerosis 2003;168(2):283-8.
2003: Humphries Steve E; Hawe Emma; Dhamrait Sukhbir; Miller George J; Talmud Philippa J
In search of genetic precision.
Lancet 2003;361(9372):1908-9; author reply 1909-10.
2003: Wong Wai-man R; Hawe Emma; Li Lai K; Miller George J; Nicaud Viviane; Pennacchio Len A; Humphries Steve E; Talmud Philippa J
Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels.
Circulation research 2003;92(9):969-75.
2003: Martin Steve; Nicaud Viviane; Humphries Steve E; Talmud Philippa J;
Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges.
Biochimica et biophysica acta 2003;1637(3):217-25.
2003: Waterworth D M; Talmud P J; Luan J; Flavell D M; Byrne C D; Humphries S E; Wareham N J
Variants in the APOC3 promoter insulin responsive element modulate insulin secretion and lipids in middle-aged men.
Biochimica et biophysica acta 2003;1637(3):200-6.
2003: Talmud Philippa J; Martin Steve; Steiner George; Flavell David M; Whitehouse David B; Nagl Sylvia; Jackson Richard; Taskinen Marja-Riitta; Frick M Heikki; Nieminen Markku S; Kesäniemi Y Antero; Pasternack Amos; Humphries Steve E; Syvänne Mikko;
Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(4):644-9.
2003: Hawe E; Talmud P J; Miller G J; Humphries S E;
Family history is a coronary heart disease risk factor in the Second Northwick Park Heart Study.
Annals of human genetics 2003;67(Pt 2):97-106.
2003: Bowyer David; Dallinga-Thie Geesje; von Eckardstein Arnold; Hofker Marten; Jauhiainen Matti; Mooser Vincent; Nimpf Johannes; Rudling Matts; Staels Bart; Talmud Philippa
European lipoprotein club: report of the 25th ELC annual conference. Tutzing, 9-12 September 2002.
Atherosclerosis 2003;167(1):159-68.
2003: Fisher Rachel M; Benhizia Ferdaous; Schreiber Renate; Makoveichuk Elena; Putt Wendy; Al-Haideri Maysoon; Deckelbaum Richard J; Olivecrona Gunilla; Humphries Steve E; Talmud Philippa J
Enhanced bridging function and augmented monocyte adhesion by lipoprotein lipase N9: insights into increased risk of coronary artery disease in N9 carriers.
Atherosclerosis 2003;166(2):243-51.
2002: Talmud Philippa J; Hawe Emma; Miller George J; Humphries Steve E
Nonfasting apolipoprotein B and triglyceride levels as a useful predictor of coronary heart disease risk in middle-aged UK men.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(11):1918-23.
2002: Talmud Philippa J; Hawe Emma; Martin Steve; Olivier Michael; Miller George J; Rubin Edward M; Pennacchio Len A; Humphries Steve E
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides.
Human molecular genetics 2002;11(24):3039-46.
2002: Talmud P J; Palmen J; Nicaud V; Tiret L;
Association of the hormone sensitive lipase -60C > G variant with fasting insulin levels in healthy young men.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2002;12(4):173-7.
2002: Humphries S E; Berglund L; Isasi C R; Otvos J D; Kaluski D; Deckelbaum R J; Shea S; Talmud P J
Loci for CETP, LPL, LIPC, and APOC3 affect plasma lipoprotein size and sub-population distribution in Hispanic and non-Hispanic white subjects: the Columbia University BioMarkers Study.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2002;12(4):163-72.
2002: Minihane Anne Marie; Finnegan Yvonne E; Talmud Philippa; Leigh-Firbank Elizabeth C; Williams Christine M
Influence of the APOC3 -2854T>G polymorphism on plasma lipid levels: effect of age and gender.
Biochimica et biophysica acta 2002;1583(3):311-4.
2002: Khan Syrah; Minihane Anne-Marie; Talmud Philippa J; Wright John W; Murphy Margaret C; Williams Christine M; Griffin Bruce A
Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype.
Journal of lipid research 2002;43(6):979-85.
2002: Dallinga-Thie G; Bowyer David; Dallinga-Thie Geesge; Dieplinger Hans; Funke Harald; Hofker Marten; Jauhiainen Matti; Nimpf Johannes; Staels Bart; Talmud Philippa; Tarugi Patricia
European Lipoprotein Club: Report of the 24th ELC Annual Conference, Tutzing, 10-13 September 2001.
Atherosclerosis 2002;162(2):439-47.
2002: Talmud Philippa J; Humphries Steve E
Gene:environment interaction in lipid metabolism and effect on coronary heart disease risk.
Current opinion in lipidology 2002;13(2):149-54.
2002: Talmud P J; Hawe E; Robertson K; Miller G J; Miller N E; Humphries S E
Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men.
Annals of human genetics 2002;66(Pt 2):111-24.
2002: Flavell David M; Jamshidi Yalda; Hawe Emma; Pineda Torra Inés; Taskinen Marja-Riitta; Frick M Heikki; Nieminen Markku S; Kesäniemi Y Antero; Pasternack Amos; Staels Bart; Miller George; Humphries Steve E; Talmud Philippa J; Syvänne Mikko
Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease.
Circulation 2002;105(12):1440-5.
2002: Talmud Philippa J; Hawe Emma; Miller George J
Analysis of gene-environment interaction in coronary artery disease: lipoprotein lipase and smoking as examples.
Italian heart journal : official journal of the Italian Federation of Cardiology 2002;3(1):6-9.
2001: Talmud P J; Palmen J; Luan J; Flavell D; Byrne C D; Waterworth D M; Wareham N J
Variation in the promoter of the human hormone sensitive lipase gene shows gender specific effects on insulin and lipid levels: results from the Ely study.
Biochimica et biophysica acta 2001;1537(3):239-44.
2001: Talmud P J; Berglund L; Hawe E M; Waterworth D M; Isasi C R; Deckelbaum R E; Starc T; Ginsberg H N; Humphries S E; Shea S
Age-related effects of genetic variation on lipid levels: The Columbia University BioMarkers Study.
Pediatrics 2001;108(3):E50.
2001: Talmud P J; Humphries S E
Genetic polymorphisms, lipoproteins and coronary artery disease risk.
Current opinion in lipidology 2001;12(4):405-9.
2001: Humphries S E; Talmud P J; Hawe E; Bolla M; Day I N; Miller G J
Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study.
Lancet 2001;358(9276):115-9.
2001: Boren J; Lookene A; Makoveichuk E; Xiang S; Gustafsson M; Liu H; Talmud P; Olivecrona G
Binding of low density lipoproteins to lipoprotein lipase is dependent on lipids but not on apolipoprotein B.
The Journal of biological chemistry 2001;276(29):26916-22.
2001: Jansen H; Waterworth D M; Nicaud V; Ehnholm C; Talmud P J;
Interaction of the common apolipoprotein C-III (APOC3 -482C > T) and hepatic lipase (LIPC -514C > T) promoter variants affects glucose tolerance in young adults. European Atherosclerosis Research Study II (EARS-II).
Annals of human genetics 2001;65(Pt 3):237-43.
2001: Benhizia F; Ginsberg H N; Humphries S E; Talmud P J
Variation in the human ApoB signal peptide modulates ApoB17 translocation.
Biochemical and biophysical research communications 2001;283(1):149-57.
2001: Hubacek J A; Waterworth D M; Poledne R; Pitha J; Skodová Z; Humphries S E; Talmud P J
Genetic determination of plasma lipids and insulin in the Czech population.
Clinical biochemistry 2001;34(2):113-8.
2001: Waterworth D M; Talmud P J; Humphries S E; Wicks P D; Sagnella G A; Strazzullo P; Alberti K G; Cook D G; Cappuccio F P
Variable effects of the APOC3-482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groups.
Diabetologia 2001;44(2):245-8.
2001: Hubácek J A; Waterworth D M; Pitha J; Humphries S E; Talmud P J; Poledne R
Polymorphisms in the lipoprotein lipase and hepatic lipase genes and plasma lipid values in the Czech population.
Physiological research / Academia Scientiarum Bohemoslovaca 2001;50(4):345-51.
2001: Humphries S E; Montgomery H E; Talmud P J
Predisposing genes, high-risk environments and coronary artery disease: LPL and fibrinogen as examples.
World review of nutrition and dietetics 2001;89():61-7.
2001: Talmud P J; Waterworth D M; Humphries S E;
Effect of genetic variation on the postprandial response. Results from the European Atherosclerosis Research Study II.
World review of nutrition and dietetics 2001;89():53-60.
2000: Waterworth D M; Talmud P J; Bujac S R; Fisher R M; Miller G J; Humphries S E
Contribution of apolipoprotein C-III gene variants to determination of triglyceride levels and interaction with smoking in middle-aged men.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(12):2663-9.
2000: Liu H; Labeur C; Xu C F; Ferrell R; Lins L; Brasseur R; Rosseneu M; Weiss K M; Humphries S E; Talmud P J
Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr.
Journal of lipid research 2000;41(11):1760-71.
2000: Minihane A M; Khan S; Talmud P J; Williams D L; Wright J W; Murphy M C; Griffin B A; Williams C M
Lack of association between lipaemia and central adiposity in subjects with an atherogenic lipoprotein phenotype (ALP).
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(9):1097-106.
2000: Minihane A M; Khan S; Leigh-Firbank E C; Talmud P; Wright J W; Murphy M C; Griffin B A; Williams C M
ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(8):1990-7.
2000: Liu H; Talmud P J; Lins L; Brasseur R; Olivecrona G; Peelman F; Vandekerckhove J; Rosseneu M; Labeur C
Characterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase.
Biochemistry 2000;39(31):9201-12.
2000: Talmud P J; Palmen J; Miller G; Humphries S E
Effect of microsomal triglyceride transfer protein gene variants (-493G > T, Q95H and H297Q) on plasma lipid levels in healthy middle-aged UK men.
Annals of human genetics 2000;64(Pt 4):269-76.
2000: Waterworth D M; Hubacek J A; Pitha J; Kovar J; Poledne R; Humphries S E; Talmud P J
Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI-APOE cluster.
Journal of lipid research 2000;41(7):1103-9.
2000: Flavell D M; Pineda Torra I; Jamshidi Y; Evans D; Diamond J R; Elkeles R S; Bujac S R; Miller G; Talmud P J; Staels B; Humphries S E
Variation in the PPARalpha gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects.
Diabetologia 2000;43(5):673-80.
2000: Talmud P J; Edwards K L; Turner C M; Newman B; Palmen J M; Humphries S E; Austin M A
Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size: use of a novel tetranucleotide repeat within the CETP promoter.
Circulation 2000;101(21):2461-6.
2000: Hall S; Talmud P J; Cook D G; Wicks P D; Rothwell M J; Strazzullo P; Sagnella G A; Cappuccio F P
Frequency and allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: the Wandsworth Heart and Stroke Study.
Genetic epidemiology 2000;18(3):203-16.
2000: Talmud P J; Bujac S R; Hall S; Miller G J; Humphries S E
Substitution of asparagine for aspartic acid at residue 9 (D9N) of lipoprotein lipase markedly augments risk of ischaemic heart disease in male smokers.
Atherosclerosis 2000;149(1):75-81.
2000: Talmud P J; Waterworth D M
In-vivo and in-vitro nutrient-gene interactions.
Current opinion in lipidology 2000;11(1):31-6.
1999: Waterworth D M; Ribalta J; Nicaud V; Dallongeville J; Humphries S E; Talmud P
ApoCIII gene variants modulate postprandial response to both glucose and fat tolerance tests.
Circulation 1999;99(14):1872-7.
1999: Montgomery H; Clarkson P; Barnard M; Bell J; Brynes A; Dollery C; Hajnal J; Hemingway H; Mercer D; Jarman P; Marshall R; Prasad K; Rayson M; Saeed N; Talmud P; Thomas L; Jubb M; World M; Humphries S
Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training.
Lancet 1999;353(9152):541-5.
1999: Jansen H; Chu G; Ehnholm C; Dallongeville J; Nicaud V; Talmud P J
The T allele of the hepatic lipase promoter variant C-480T is associated with increased fasting lipids and HDL and increased preprandial and postprandial LpCIII:B : European Atherosclerosis Research Study (EARS) II.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):303-8.
1998: Talmud P J; Palmen J; Walker M
Identification of genetic variation in the human hormone-sensitive lipase gene and 5' sequences: homology of 5' sequences with mouse promoter and identification of potential regulatory elements.
Biochemical and biophysical research communications 1998;252(3):661-8.
1998: Humphries S E; Luong L A; Talmud P J; Frick M H; Kesäniemi Y A; Pasternack A; Taskinen M R; Syvänne M
The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. Lopid Coronary Angiography Trial.
Atherosclerosis 1998;139(1):49-56.
1998: Talmud P J; Hall S; Holleran S; Ramakrishnan R; Ginsberg H N; Humphries S E
LPL promoter -93T/G transition influences fasting and postprandial plasma triglycerides response in African-Americans and Hispanics.
Journal of lipid research 1998;39(6):1189-96.
1998: Humphries S E; Nicaud V; Margalef J; Tiret L; Talmud P J
Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS).
Arteriosclerosis, thrombosis, and vascular biology 1998;18(4):526-34.
1997: Fisher R M; Humphries S E; Talmud P J
Common variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis.
Atherosclerosis 1997;135(2):145-59.
1997: Hall S; Chu G; Miller G; Cruickshank K; Cooper J A; Humphries S E; Talmud P J
A common mutation in the lipoprotein lipase gene promoter, -93T/G, is associated with lower plasma triglyceride levels and increased promoter activity in vitro.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):1969-76.
1997: Montgomery H E; Clarkson P; Dollery C M; Prasad K; Losi M A; Hemingway H; Statters D; Jubb M; Girvain M; Varnava A; World M; Deanfield J; Talmud P; McEwan J R; McKenna W J; Humphries S
Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training.
Circulation 1997;96(3):741-7.
1997: Gerdes C; Fisher R M; Nicaud V; Boer J; Humphries S E; Talmud P J; Faergeman O
Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations: studies in the fasting and postprandial states: the European Atherosclerosis Research Studies.
Circulation 1997;96(3):733-40.
1997: Syvänne M; Talmud P J; Humphries S E; Fisher R M; Rosseneu M; Hilden H; Taskinen M R
Determinants of postprandial lipemia in men with coronary artery disease and low levels of HDL cholesterol.
Journal of lipid research 1997;38(7):1463-72.
1997: Talmud P J; Humphries S E
Apolipoprotein C-III gene variation and dyslipidaemia.
Current opinion in lipidology 1997;8(3):154-8.
1997: Mailly F; Palmen J; Muller D P; Gibbs T; Lloyd J; Brunzell J; Durrington P; Mitropoulos K; Betteridge J; Watts G; Lithell H; Angelico F; Humphries S E; Talmud P J
Familial lipoprotein lipase (LPL) deficiency: a catalogue of LPL gene mutations identified in 20 patients from the UK, Sweden, and Italy.
Human mutation 1997;10(6):465-73.
1996: de Bruin T W; Mailly F; van Barlingen H H; Fisher R; Castro Cabezas M; Talmud P; Dallinga-Thie G M; Humphries S E
Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia.
European journal of clinical investigation 1996;26(8):631-9.
1996: Bagdade J D; Ritter M C; Lithell H; Bassett D; Mailly F; Talmud P; Hayden M R
Reduced cholesteryl ester transfer in plasma of patients with lipoprotein lipase deficiency.
Journal of lipid research 1996;37(8):1696-703.
1996: Talmud P J; Tamplin O J; Heath K; Gaffney D; Day I N; Humphries S E
Rapid testing for three mutations causing familial defective apolipoprotein B100 in 562 patients with familial hypercholesterolaemia.
Atherosclerosis 1996;125(1):135-7.
1996: Mailly F; Fisher R M; Nicaud V; Luong L A; Evans A E; Marques-Vidal P; Luc G; Arveiler D; Bard J M; Poirier O; Talmud P J; Humphries S E
Association between the LPL-D9N mutation in the lipoprotein lipase gene and plasma lipid traits in myocardial infarction survivors from the ECTIM Study.
Atherosclerosis 1996;122(1):21-8.
1995: Panahloo A; Andrès C; Mohamed-Ali V; Gould M M; Talmud P; Humphries S E; Yudkin J S
The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?
Circulation 1995;92(12):3390-3.
1995: Humphries S E; Peacock R E; Talmud P J
The genetic determinants of plasma cholesterol and response to diet.
Baillière's clinical endocrinology and metabolism 1995;9(4):797-823.
1995: Talmud P
Bimonthly update in lipidology: Genetics and molecular biology.
Current opinion in lipidology 1995;6(5):U120-3.
1995: Humphries S E; Talmud P J
Hyperlipidaemia associated with genetic variation in the apolipoprotein B gene.
Current opinion in lipidology 1995;6(4):215-22.
1995: Peacock R E; Karpe F; Talmud P J; Hamsten A; Humphries S E
Common variation in the gene for apolipoprotein B modulates postprandial lipoprotein metabolism: a hypothesis generating study.
Atherosclerosis 1995;116(1):135-45.
1994: Xu C F; Talmud P; Schuster H; Houlston R; Miller G; Humphries S
Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia.
Clinical genetics 1994;46(6):385-97.
1994: Xu C F; Talmud P; Humphries S
Three new polymorphisms of the ApoAI-CIII-AIV gene cluster.
Molecular and cellular probes 1994;8(4):331-2.
1994: Seed M; Mailly F; Vallance D; Doherty E; Winder A; Talmud P; Humphries S E
Lipoprotein lipase activity in patients with combined hyperlipidaemia.
The Clinical investigator 1994;72(2):100-6.
1994: Talmud P J; Ye S; Humphries S E
Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis Research Study.
Genetic epidemiology 1994;11(3):265-80.
1993: Humphries S E; Mailly F; Gudnason V; Talmud P
The molecular genetics of pediatric lipid disorders: recent progress and future research directions.
Pediatric research 1993;34(4):403-15.
1992: Humphries S E; Dunning A; Xu C F; Peacock R; Talmud P; Hamsten A
DNA polymorphism studies. Approaches to elucidating multifactorial ischaemic heart disease: the apo B gene as an example.
Annals of medicine 1992;24(5):349-56.
1992: Talmud P J; Converse C; Krul E; Huq L; McIlwaine G G; Series J J; Boyd P; Schonfeld G; Dunning A; Humphries S
A novel truncated apolipoprotein B (apo B55) in a patient with familial hypobetalipoproteinemia and atypical retinitis pigmentosa.
Clinical genetics 1992;42(2):62-70.
1992: Peacock R; Dunning A; Hamsten A; Tornvall P; Humphries S; Talmud P
Apolipoprotein B gene polymorphisms, lipoproteins and coronary atherosclerosis: a study of young myocardial infarction survivors and healthy population-based individuals.
Atherosclerosis 1992;92(2-3):151-64.
1992: Talmud P J; Boerwinkle E; Xu C F; Tikkanen M J; Pietinen P; Huttunen J K; Humphries S
Dietary intake and gene variation influence the response of plasma lipids to dietary intervention.
Genetic epidemiology 1992;9(4):249-60.
1991: Talmud P; Tybjaerg-Hansen A; Bhatnagar D; Mbewu A; Miller J P; Durrington P; Humphries S
Rapid screening for specific mutations in patients with a clinical diagnosis of familial hypercholesterolaemia.
Atherosclerosis 1991;89(2-3):137-41.
1991: Wagner R D; Krul E S; Tang J; Parhofer K G; Garlock K; Talmud P; Schonfeld G
ApoB-54.8, a truncated apolipoprotein found primarily in VLDL, is associated with a nonsense mutation in the apoB gene and hypobetalipoproteinemia.
Journal of lipid research 1991;32(6):1001-11.
1991: Myant N B; Gallagher J J; Knight B L; McCarthy S N; Frostegård J; Nilsson J; Hamsten A; Talmud P; Humphries S E
Clinical signs of familial hypercholesterolemia in patients with familial defective apolipoprotein B-100 and normal low density lipoprotein receptor function.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(3):691-703.
1991: Mailly F; Xu C F; Xhignesse M; Lussier-Cacan S; Talmud P J; Davignon J; Humphries S E; Nestruck A C
Characterization of a new apolipoprotein E5 variant detected in two French-Canadian subjects.
Journal of lipid research 1991;32(4):613-20.
1991: Xu C F; Talmud P J; Angelico F; Del Ben M; Savill J; Humphries S E
Apolipoprotein E polymorphism and plasma lipid, lipoprotein, and apolipoprotein levels in Italian children.
Genetic epidemiology 1991;8(6):389-98.
1990: Xu C F; Nanjee M N; Savill J; Talmud P J; Angelico F; Del Ben M; Antonini R; Mazzarella B; Miller N; Humphries S E
Variation at the apolipoprotein (apo) AI-CIII-AIV gene cluster and apo B gene loci is associated with lipoprotein and apolipoprotein levels in Italian children.
American journal of human genetics 1990;47(3):429-39.
1990: Xu C F; Tikkanen M J; Huttunen J K; Pietinen P; Bütler R; Humphries S; Talmud P
Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.
Journal of lipid research 1990;31(7):1255-61.
1990: Tikkanen M J; Xu C F; Hämäläinen T; Talmud P; Sarna S; Huttunen J K; Pietinen P; Humphries S
XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention.
Clinical genetics 1990;37(5):327-34.
1990: Tybjaerg-Hansen A; Gallagher J; Vincent J; Houlston R; Talmud P; Dunning A M; Seed M; Hamsten A; Humphries S E; Myant N B
Familial defective apolipoprotein B-100: detection in the United Kingdom and Scandinavia, and clinical characteristics of ten cases.
Atherosclerosis 1990;80(3):235-42.
1990: Menzel H J; Dieplinger H; Lackner C; Hoppichler F; Lloyd J K; Muller D R; Labeur C; Talmud P J; Utermann G
Abetalipoproteinemia with an ApoB-100-lipoprotein(a) glycoprotein complex in plasma. Indication for an assembly defect.
The Journal of biological chemistry 1990;265(2):981-6.
1990: Xu C F; Boerwinkle E; Tikkanen M J; Huttunen J K; Humphries S E; Talmud P J
Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change.
Genetic epidemiology 1990;7(4):261-75.
1989: Talmud P; King-Underwood L; Krul E; Schonfeld G; Humphries S
The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia.
Journal of lipid research 1989;30(11):1773-9.
1989: Krul E S; Kinoshita M; Talmud P; Humphries S E; Turner S; Goldberg A C; Cook K; Boerwinkle E; Schonfeld G
Two distinct truncated apolipoprotein B species in a kindred with hypobetalipoproteinemia.
Arteriosclerosis (Dallas, Tex.) 1989;9(6):856-68.
1988: Talmud P J; Lloyd J K; Muller D P; Collins D R; Scott J; Humphries S
Genetic evidence from two families that the apolipoprotein B gene is not involved in abetalipoproteinemia.
The Journal of clinical investigation 1988;82(5):1803-6.
1987: Talmud P J; Barni N; Kessling A M; Carlsson P; Darnfors C; Bjursell G; Galton D; Wynn V; Kirk H; Hayden M R
Apolipoprotein B gene variants are involved in the determination of serum cholesterol levels: a study in normo- and hyperlipidaemic individuals.
Atherosclerosis 1987;67(1):81-9.
1987: Humphries S E; Talmud P J; Kessling A M
Use of DNA polymorphisms of the apolipoprotein genes to study the role of genetic variation in the determination of serum lipid levels.
Ciba Foundation symposium 1987;130():128-49.

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