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Shinri Tamura

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Physiology

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Publications

TOP 3
Toko Chida; Masakatsu Ando; Yutaro Masu; Tasuku Matsuki; Yuko Nagaura; Teruko Takano-Yamamoto; Shinri Tamura; Takayasu Kobayashi
N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.
Yasuharu Shinoda; Shinri Tamura; Hiroyuki Matsui; Yuko Nagaura; Satoko Saito; Kohsuke Fujita; Kohji Fukunaga; Yusuke Kanto; Takayasu Kobayashi
Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites.
Naoto Fukuno; Hiroyuki Matsui; Yoshiaki Kanda; Osamu Suzuki; Kunihiro Matsumoto; Keiichi Sasaki; Takayasu Kobayashi; Shinri Tamura
TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts.

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All Publications

2013: Toko Chida; Masakatsu Ando; Yutaro Masu; Tasuku Matsuki; Yuko Nagaura; Teruko Takano-Yamamoto; Shinri Tamura; Takayasu Kobayashi
N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.
The Biochemical journal 2013;449(3):741-9.
2012: Yasuharu Shinoda; Shinri Tamura; Hiroyuki Matsui; Yuko Nagaura; Satoko Saito; Kohsuke Fujita; Kohji Fukunaga; Yusuke Kanto; Takayasu Kobayashi
Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites.
FEBS letters 2012;586(19):3024-9.
2011: Naoto Fukuno; Hiroyuki Matsui; Yoshiaki Kanda; Osamu Suzuki; Kunihiro Matsumoto; Keiichi Sasaki; Takayasu Kobayashi; Shinri Tamura
TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts.
Biochemical and biophysical research communications 2011;408(2):202-7.
2010: Tada-aki Kudo; Hiroyasu Kanetaka; Akira Watanabe; Ayako Okumoto; Masanobu Asano; Ye Zhang; Fei Zhao; Mitsuhiro Kano; Yoshinaka Shimizu; Shinri Tamura; Haruhide Hayashi
Investigating bone morphogenetic protein (BMP) signaling in a newly established human cell line expressing BMP receptor type II.
The Tohoku journal of experimental medicine 2010;222(2):121-9.
2009: Takeaki Henmi; Kazutaka Amano; Yuko Nagaura; Kunihiro Matsumoto; Seishi Echigo; Shinri Tamura; Takayasu Kobayashi
A mechanism for the suppression of interleukin-1-induced nuclear factor kappaB activation by protein phosphatase 2Ceta-2.
The Biochemical journal 2009;423(1):71-8.
2008: Kenjiro Awano; Kazutaka Amano; Yuko Nagaura; Shin-ichiro Kanno; Seishi Echigo; Shinri Tamura; Takayasu Kobayashi
Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity.
Biochemistry 2008;47(27):7248-55.
2008: Satoko Saito; Hiroyuki Matsui; Miyuki Kawano; Keigo Kumagai; Nario Tomishige; Kentaro Hanada; Seishi Echigo; Shinri Tamura; Takayasu Kobayashi
Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes.
The Journal of biological chemistry 2008;283(10):6584-93.
2007: Jun-ichi Saito; Shinnosuke Toriumi; Kenjiro Awano; Hidenori Ichijo; Keiichi Sasaki; Takayasu Kobayashi; Shinri Tamura
Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon.
The Biochemical journal 2007;405(3):591-6.
2007: Masato Sasaki; Motoko Ohnishi; Fumi Tashiro; Hitoshi Niwa; Akira Suzuki; Jun-ichi Miyazaki; Takayasu Kobayashi; Shinri Tamura
Disruption of the mouse protein Ser/Thr phosphatase 2Cbeta gene leads to early pre-implantation lethality.
Mechanisms of development 2007;124(6):489-99.
2006: Tomoharu Takeuchi; Takayasu Kobayashi; Shinri Tamura; Hideyoshi Yokosawa
Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation.
FEBS letters 2006;580(18):4521-6.
2006: Shinri Tamura; Shinnosuke Toriumi; Jun-Ichi Saito; Kenjiro Awano; Tada-Aki Kudo; Takayasu Kobayashi
PP2C family members play key roles in regulation of cell survival and apoptosis.
Cancer science 2006;97(7):563-7.
2006: Akira Hiraga; Nick Morrice; Eiko Honda; Shinri Tamura; Hiroshi Munakata
Clathrin light chain b is capable of affecting potently a major protein phosphatase from microtubules (MT-PP1).
FEBS letters 2006;580(5):1425-30.
2005: Keisuke Maki; Rie Motoki; Kunihiko Fujii; Motomu Kanai; Takayasu Kobayashi; Shinri Tamura; Masakatsu Shibasaki
Catalyst-controlled asymmetric synthesis of fostriecin and 8-epi-fostriecin.
Journal of the American Chemical Society 2005;127(48):17111-7.
2005: Sayaka Teramoto; Fumiko Kihara-Negishi; Takuya Sakurai; Toshiyuki Yamada; Tomoko Hashimoto-Tamaoki; Shinri Tamura; Seiichi Kohno; Tsuneyuki Oikawa
Classification of neural differentiation-associated genes in P19 embryonal carcinoma cells by their expression patterns induced after cell aggregation and/or retinoic acid treatment.
Oncology reports 2005;14(5):1231-8.
2005: Takayasu Kobayashi; Masato Sasaki; Shinri Tamura
[Regulation of stress-activated signal pathways by protein phosphatase 2C].
Seikagaku. The Journal of Japanese Biochemical Society 2005;77(10):1274-80.
2004: Shoko Akiyama; Takayuki Yonezawa; Tada-Aki Kudo; Ming Guang Li; Hong Wang; Michihiko Ito; Katsuji Yoshioka; Jun Ninomiya-Tsuji; Kunihiro Matsumoto; Ryunosuke Kanamaru; Shinri Tamura; Takayasu Kobayashi
Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells.
The Journal of biological chemistry 2004;279(35):36616-20.
2004: Takeshi Yoshizaki; Hiroshi Maegawa; Katsuya Egawa; Satoshi Ugi; Yoshihiko Nishio; Takeshi Imamura; Takayasu Kobayashi; Shinri Tamura; Jerrold M Olefsky; Atsunori Kashiwagi
Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes.
The Journal of biological chemistry 2004;279(21):22715-26.
2003: Ken-ichiro Komaki; Koji Katsura; Motoko Ohnishi; Ming Guang Li; Masato Sasaki; Makoto Watanabe; Takayasu Kobayashi; Shinri Tamura
Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.
Biochimica et biophysica acta 2003;1630(2-3):130-7.
2003: Takayasu Kobayashi; Satoe Ebihara; Kenji Ishii; Takayasu Kobayashi; Michiharu Nishijima; Shunro Endo; Akira Takaku; Hiroyuki Sakagami; Hisatake Kondo; Fumi Tashiro; Jun-ichi Miyazaki; Kunihiko Obata; Shinri Tamura; Yuchio Yanagawa
Structural and functional characterization of mouse glutamate decarboxylase 67 gene promoter.
Biochimica et biophysica acta 2003;1628(3):156-68.
2003: Ming Guang Li; Koji Katsura; Hisayuki Nomiyama; Ken-ichiro Komaki; Jun Ninomiya-Tsuji; Kunihiro Matsumoto; Takayasu Kobayashi; Shinri Tamura
Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon).
The Journal of biological chemistry 2003;278(14):12013-21.
2003: Tada-aki Kudo; Yoshiyuki Sakamoto; Shinri Tamura; Takayasu Kobayashi
Activation mechanism of c-Jun amino-terminal kinase in the course of endodermal differentiation of P19 embryonic carcinoma cells.
FEBS letters 2003;539(1-3):29-33.
2003: Mitsuhiro Kashiwaba; Koji Katsura; Motoko Ohnishi; Mutsuo Sasaki; Hiromitsu Tanaka; Yoshitake Nishimune; Takayasu Kobayashi; Shinri Tamura
A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.
FEBS letters 2003;538(1-3):197-202.
2002: Shinri Tamura; Masahito Hanada; Masato Sasaki; Ken-ichiro Komaki; Takayuki Yonezawa; Takayasu Kobayashi
[Regulation of stress-activated protein kinase signaling pathways by protein phosphatases].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(5):568-75.
2002: Shinri Tamura; Masahito Hanada; Motoko Ohnishi; Koji Katsura; Masato Sasaki; Takayasu Kobayashi
Regulation of stress-activated protein kinase signaling pathways by protein phosphatases.
European journal of biochemistry / FEBS 2002;269(4):1060-6.
2001: Hong Wang; S Ikeda; S Kanno; L M Guang; Motoko Ohnishi; M Sasaki; Takayasu Kobayashi; Shinri Tamura
Activation of c-Jun amino-terminal kinase is required for retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells.
FEBS letters 2001;503(1):91-6.
2001: Masahito Hanada; Jun Ninomiya-Tsuji; Ken-ichiro Komaki; Motoko Ohnishi; Koji Katsura; Ryunosuke Kanamaru; Kunihiro Matsumoto; Shinri Tamura
Regulation of the TAK1 signaling pathway by protein phosphatase 2C.
The Journal of biological chemistry 2001;276(8):5753-9.
2000: Kimitoshi Makinae; Takayasu Kobayashi; T Kobayashi; H Shinkawa; H Sakagami; H Kondo; Fumi Tashiro; J Miyazaki; K Obata; Shinri Tamura; Yuchio Yanagawa
Structure of the mouse glutamate decarboxylase 65 gene and its promoter: preferential expression of its promoter in the GABAergic neurons of transgenic mice.
Journal of neurochemistry 2000;75(4):1429-37.
1999: Motoko Ohnishi; N Chida; Takayasu Kobayashi; Hong Wang; S Ikeda; Masahito Hanada; Y Yanagawa; Koji Katsura; Akira Hiraga; Shinri Tamura
Alternative promoters direct tissue-specific expression of the mouse protein phosphatase 2Cbeta gene.
European journal of biochemistry / FEBS 1999;263(3):736-45.
1999: Y Yanagawa; T Kobayashi; M Ohnishi; T Kobayashi; Shinri Tamura; T Tsuzuki; M Sanbo; T Yagi; F Tashiro; J Miyazaki
Enrichment and efficient screening of ES cells containing a targeted mutation: the use of DT-A gene with the polyadenylation signal as a negative selection maker.
Transgenic research 1999;8(3):215-21.
1998: Masahito Hanada; Takayasu Kobayashi; Motoko Ohnishi; S Ikeda; Hong Wang; Koji Katsura; Y Yanagawa; Akira Hiraga; Ryunosuke Kanamaru; Shinri Tamura
Selective suppression of stress-activated protein kinase pathway by protein phosphatase 2C in mammalian cells.
FEBS letters 1998;437(3):172-6.
1998: Takayasu Kobayashi; K Kusuda; Motoko Ohnishi; Hong Wang; S Ikeda; Masahito Hanada; Y Yanagawa; Shinri Tamura
Isoform specific phosphorylation of protein phosphatase 2C expressed in COS7 cells.
FEBS letters 1998;430(3):222-6.
1998: Shinri Tamura; T Kobayashi; M Ohnishi; N Chida; M Hanada
[Structure and function of mammalian protein phosphatase 2C].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(8 Suppl):959-67.
1998: Shinri Tamura
[Protein serine/threonine phosphatases].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(8 Suppl):935-6.
1998: K Kusuda; Takayasu Kobayashi; S Ikeda; Motoko Ohnishi; N Chida; Y Yanagawa; Ryuzaburo Shineha; T Nishihira; S Satomi; Akira Hiraga; Shinri Tamura
Mutational analysis of the domain structure of mouse protein phosphatase 2Cbeta.
The Biochemical journal 1998;332 ( Pt 1)():243-50.
1998: T Kobayashi; K Kusuda; M Ohnishi; N Chida; Shinri Tamura
Expression of mouse protein phosphatase 2C in Escherichia coli and COS 7 cells.
Methods in molecular biology (Clifton, N.J.) 1998;93():185-9.
1997: T Kobayashi; Y Sasahara; Y Yanagawa; Shinri Tamura
[Roles of protein Ser/Thr phosphatases in regulation of neural cell functions].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(3 Suppl):439-45.
1996: S Kato; Takayasu Kobayashi; K Kusuda; Y Nishina; Y Nishimune; K Yomogida; M Yamamoto; H Sakagami; H Kondo; Motoko Ohnishi; N Chida; Y Yanagawa; Shinri Tamura
Differentiation-dependent enhanced expression of protein phosphatase 2Cbeta in germ cells of mouse seminiferous tubules.
FEBS letters 1996;396(2-3):293-7.
1996: Y Sasahara; Takayasu Kobayashi; H Onodera; M Onoda; Motoko Ohnishi; S Kato; K Kusuda; H Shima; M Nagao; H Abe; Y Yanagawa; Akira Hiraga; Shinri Tamura
Okadaic acid suppresses neural differentiation-dependent expression of the neurofilament-L gene in P19 embryonal carcinoma cells by post-transcriptional modification.
The Journal of biological chemistry 1996;271(42):25950-7.
1996: Takayasu Kobayashi; A Yasui; Motoko Ohnishi; S Kato; Y Sasahara; K Kusuda; N Chida; Y Yanagawa; Akira Hiraga; Shinri Tamura
Enhanced UV sensitivity of yeast cells induced by overexpression of Mg(2+)-dependent protein phosphatase alpha (type 2C alpha).
Mutation research 1996;362(3):213-7.
1996: Motoko Ohnishi; K Nakagawara; M Mori; T Kobayashi; S Kato; Y Sasahara; K Kusuda; N Chida; T Kobayashi; Y Yanagawa; Akira Hiraga; T Takeuchi; Shinri Tamura
Localization of the mouse protein serine/threonine phosphatase 2C beta gene to chromosome 17E 4-5.
Genomics 1996;32(1):134-6.
1995: S Kato; T Terasawa; T Kobayashi; Motoko Ohnishi; Y Sasahara; K Kusuda; Y Yanagawa; Akira Hiraga; Y Matsui; Shinri Tamura
Molecular cloning and expression of mouse mg(2+)-dependent protein phosphatase beta-4 (type 2C beta-4).
Archives of biochemistry and biophysics 1995;318(2):387-93.
1994: S Kato; T Kobayashi; T Terasawa; Motoko Ohnishi; Y Sasahara; R Kanamaru; Shinri Tamura
The cDNA sequence encoding mouse Mg2+ -dependent protein phosphatase alpha.
Gene 1994;145(2):311-2.
1994: T Murakami; Takayasu Kobayashi; T Terasawa; Motoko Ohnishi; S Kato; Y Sasahara; M Itoh; T Nakano; Shinri Tamura
Characterization of multiple molecular forms of Mg(2+)-dependent protein phosphatase from Saccharomyces cerevisiae.
Journal of biochemistry 1994;115(4):762-6.
1993: T Terasawa; T Kobayashi; T Murakami; Motoko Ohnishi; S Kato; O Tanaka; H Kondo; H Yamamoto; T Takeuchi; Shinri Tamura
Molecular cloning of a novel isotype of Mg(2+)-dependent protein phosphatase beta (type 2C beta) enriched in brain and heart.
Archives of biochemistry and biophysics 1993;307(2):342-9.