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Suet-Mien Tan

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Chemicals & Drugs

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Publications

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Chun Loong Ho; Kavin Shi Jie Chong; Mary Lay Cheng Chuah; Jamila Akosua Oppong; Suet-Mien Tan; Zhao-Xun Liang
Visualizing the perturbation of cellular cyclic di-GMP levels in bacterial cells.
Zhi-Hong Xue; Chen Feng; Wei-Ling Liu; Suet-Mien Tan
A role of kindlin-3 in integrin αMβ2 outside-in signaling and the Syk-Vav1-Rac1/Cdc42 signaling axis.
Geok-Lin Chua; Alok Tanala Patra; Suet-Mien Tan; Surajit Bhattacharjya
NMR structure of integrin α4 cytosolic tail and its interactions with paxillin.

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All Publications

2013: Chun Loong Ho; Kavin Shi Jie Chong; Mary Lay Cheng Chuah; Jamila Akosua Oppong; Suet-Mien Tan; Zhao-Xun Liang
Visualizing the perturbation of cellular cyclic di-GMP levels in bacterial cells.
Journal of the American Chemical Society 2013;135(2):566-9.
2013: Zhi-Hong Xue; Chen Feng; Wei-Ling Liu; Suet-Mien Tan
A role of kindlin-3 in integrin αMβ2 outside-in signaling and the Syk-Vav1-Rac1/Cdc42 signaling axis.
PloS one 2013;8(2):e56911.
2013: Geok-Lin Chua; Alok Tanala Patra; Suet-Mien Tan; Surajit Bhattacharjya
NMR structure of integrin α4 cytosolic tail and its interactions with paxillin.
PloS one 2013;8(1):e55184.
2012: David Ruiz Carrillo; Suet-Mien Tan; Ramya Chandrasekaran; Tobias Cornvik; Chong Wai Liew; Martina Nilsson; Julien Lescar
Structure of human Rack1 protein at a resolution of 2.45 Å.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 8):867-72.
2012: Suet-Mien Tan
The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.
Bioscience reports 2012;32(3):241-69.
2012: Chen Feng; Hui-Shan Lee; Yan-Feng Li; Wei-Min Lim; Christiane Ruedl; Susana G Shochat; Xiao-Yan Tang; Zhi-Hong Xue; Yin-Hoe Yau; Yi-Chao Zhou; Tobias C Cornvik; Suet-Mien Tan
Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1).
The Journal of biological chemistry 2012;287(14):10714-26.
2012: Geok-Lin Chua; Alok Tanala Patra; Suet-Mien Tan; Xiao-Yan Tang; Surajit Bhattacharjya
Structure and binding interface of the cytosolic tails of αXβ2 integrin.
PloS one 2012;7(7):e41924.
2011: Royston-Luke Huang; Sander Kersten; Chee Ren Ivan Lam; David Tai Wei Leong; Hoi-Yeung Li; Ming Keat Sng; Chek Kun Tan; Ming Jie Tan; Han Chung Chong; Jeak Ling Ding; Suet-Mien Tan; Ziqiang Teo; Pengcheng Zhu; Nguan Soon Tan
ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters.
Blood 2011;118(14):3990-4002.
2011: Choon-Peng Chng; Suet-Mien Tan
Leukocyte integrin αLβ2 transmembrane association dynamics revealed by coarse-grained molecular dynamics simulations.
Proteins 2011;79(7):2203-13.
2011: Garnet Suck; Suet-Mien Tan; Sixian Chu; Madelaine Niam; Ardcharaporn Vararattanavech; Tsyr Jong Lim; Mickey B C Koh
KHYG-1 and NK-92 represent different subtypes of LFA-1-mediated NK cell adhesiveness.
Frontiers in bioscience (Elite edition) 2011;3():166-78.
2010: Yan Yih Goh; Mintu Pal; Han Chung Chong; Pengcheng Zhu; Ming Jie Tan; Lakshmi Punugu; Chee Ren Ivan Lam; Yin Hoe Yau; Chek Kun Tan; Royston-Luke Huang; Suet-Mien Tan; Mark Boon Yang Tang; Jeak Ling Ding; Sander Kersten; Nguan Soon Tan
Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration.
The American journal of pathology 2010;177(6):2791-803.
2010: Ardcharaporn Vararattanavech; Choon-Peng Chng; Krupakar Parthasarathy; Xiao-Yan Tang; Jaume Torres; Suet-Mien Tan
A transmembrane polar interaction is involved in the functional regulation of integrin alpha L beta 2.
Journal of molecular biology 2010;398(4):569-83.
2010: Zhi-Hong Xue; Chang-Qing Zhao; Geok-Lin Chua; Sze-Wah Tan; Xiao-Yan Tang; Siew-Cheng Wong; Suet-Mien Tan
Integrin alphaMbeta2 clustering triggers phosphorylation and activation of protein kinase C delta that regulates transcription factor Foxp1 expression in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3697-709.
2010: Prerana Domadia; Yan-Feng Li; Anirban Bhunia; Harini Mohanram; Suet-Mien Tan; Surajit Bhattacharjya
Functional and structural characterization of the talin F0F1 domain.
Biochemical and biophysical research communications 2010;391(1):159-65.
2009: Anirban Bhunia; Xiao-Yan Tang; Harini Mohanram; Suet-Mien Tan; Surajit Bhattacharjya
NMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tails.
The Journal of biological chemistry 2009;284(6):3873-84.
2009: Ardcharaporn Vararattanavech; Xin Lin; Jaume Torres; Suet-Mien Tan
Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunits.
The Journal of biological chemistry 2009;284(5):3239-49.
2008: Man-Li Tang; Ardcharaporn Vararattanavech; Suet-Mien Tan
Urokinase-type plasminogen activator receptor induces conformational changes in the integrin alphaMbeta2 headpiece and reorientation of its transmembrane domains.
The Journal of biological chemistry 2008;283(37):25392-403.
2008: Krupakar Parthasarathy; Xin Lin; Suet-Mien Tan; S K Alex Law; Jaume Torres
Transmembrane helices that form two opposite homodimeric interactions: an asparagine scan study of alphaM and beta2 integrins.
Protein science : a publication of the Protein Society 2008;17(5):930-8.
2008: Xiao-Yan Tang; Yan-Feng Li; Suet-Mien Tan
Intercellular adhesion molecule-3 binding of integrin alphaL beta2 requires both extension and opening of the integrin headpiece.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4793-804.
2008: Ardcharaporn Vararattanavech; Man-Li Tang; Hoi-Yeung Li; CHI HANG WONG; S K Alex Law; Jaume Torres; Suet-Mien Tan
Permissive transmembrane helix heterodimerization is required for the expression of a functional integrin.
The Biochemical journal 2008;410(3):495-502.
2007: Minlong Shi; Shen Yun Foo; Suet-Mien Tan; Edward P Mitchell; S K Alex Law; Julien Lescar
A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins.
The Journal of biological chemistry 2007;282(41):30198-206.
2007: Yan-Feng Li; Ren-Hong Tang; Kia-Joo Puan; S K Alex Law; Suet-Mien Tan
The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.
The Journal of biological chemistry 2007;282(33):24310-9.
2007: Ming Cheng; Shen Yun Foo; Min-Long Shi; Ren-Hong Tang; Le-Sheng Kong; S K Alex Law; Suet-Mien Tan
Mutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.
The Journal of biological chemistry 2007;282(25):18225-32.
2006: Xin Lin; Suet-Mien Tan; S K Alex Law; Jaume Torres
Unambiguous prediction of human integrin transmembrane heterodimer interactions using only homologous sequences.
Proteins 2006;65(2):274-9.
2006: Man-Li Tang; Le-Sheng Kong; S K Alex Law; Suet-Mien Tan
Down-regulation of integrin alpha M beta 2 ligand-binding function by the urokinase-type plasminogen activator receptor.
Biochemical and biophysical research communications 2006;348(3):1184-93.
2006: Ren-Hong Tang; S K Alex Law; Suet-Mien Tan
Selective recruitment of src family kinase Hck by leukocyte integrin alphaMbeta2 but not alphaLbeta2 or alphaXbeta2.
FEBS letters 2006;580(18):4435-42.
2006: Xin Lin; Suet-Mien Tan; S K Alex Law; Jaume Torres
Two types of transmembrane homomeric interactions in the integrin receptor family are evolutionarily conserved.
Proteins 2006;63(1):16-23.
2005: Susannah E Walters; Ren-Hong Tang; Ming Cheng; Suet-Mien Tan; S K Alex Law
Differential activation of LFA-1 and Mac-1 ligand binding domains.
Biochemical and biophysical research communications 2005;337(1):142-8.
2005: MinLong Shi; Kumar Sundramurthy; Bin Liu; Suet-Mien Tan; S K Alex Law; Julien Lescar
The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin beta2 subunit at 1.8-A resolution.
The Journal of biological chemistry 2005;280(34):30586-93.
2005: Ren-Hong Tang; Emilia Tng; S K Alex Law; Suet-Mien Tan
Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.
The Journal of biological chemistry 2005;280(32):29208-16.
2005: Xin Geng; Ren-Hong Tang; S K Alex Law; Suet-Mien Tan
Integrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1.
Immunology 2005;115(3):347-57.
2004: Emilia Tng; Suet-Mien Tan; Shoba Ranganathan; Ming Cheng; S K Alex Law
The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain.
The Journal of biological chemistry 2004;279(52):54334-9.
2001: Jonathan M Shaw; A Al-Shamkhani; Laurence A Boxer; C D Buckley; Alister W Dodds; N Klein; S M Nolan; I Roberts; D Roos; SL Scarth; D L Simmons; Suet-Mien Tan; S K Alex Law
Characterization of four CD18 mutants in leucocyte adhesion deficient (LAD) patients with differential capacities to support expression and function of the CD11/CD18 integrins LFA-1, Mac-1 and p150,95.
Clinical and experimental immunology 2001;126(2):311-8.
2001: Suet-Mien Tan; M K Robinson; K Drbal; Y van Kooyk; Jonathan M Shaw; S K Alex Law
The N-terminal region and the mid-region complex of the integrin beta 2 subunit.
The Journal of biological chemistry 2001;276(39):36370-6.
2001: Suet-Mien Tan; S E Walters; EC Mathew; M K Robinson; K Drbal; Jonathan M Shaw; S K Alex Law
Defining the repeating elements in the cysteine-rich region (CRR) of the CD18 integrin beta 2 subunit.
FEBS letters 2001;505(1):27-30.
2001: RH Hyland; WA Douglass; Suet-Mien Tan; S K Alex Law
Chimeras of the integrin beta subunit mid-region reveal regions required for heterodimer formation and for activation.
Cell communication & adhesion 2001;8(2):61-9.
2000: Suet-Mien Tan; RH Hyland; A Al-Shamkhani; WA Douglass; Jonathan M Shaw; S K Alex Law
Effect of integrin beta 2 subunit truncations on LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) assembly, surface expression, and function.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2574-81.