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Tse-Hua Tan
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11
Chen, Yi-Rong
11
Kong, Ah-Ng Tony
9
Hu, Mickey C-T
9
Meyer, Christian
9
Zhou, Guisheng
8
Yu, R
7
Shui, Jr-Wen
5
Mandlekar, Sandhya
5
Yao, Z
5
Wang, XS
5
Han, Jin
5
Diener, K
4
Kori, Rajashree
4
Qiu, WR
4
Yao, Zhengbin
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All Publications
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2009: Tucker Katherine L; Kaiser William J; Bergeron Angela L; Hu Hongbo; Dong Jing-fei; Tan Tse-Hua; Gibbins Jonathan M
Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets.
Proteomics 2009;9(18):4340-54.
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2009: Wang Hua; Song Xianzhou; Logsdon Craig; Zhou Guisheng; Evans Douglas B; Abbruzzese James L; Hamilton Stanley R; Tan Tse-Hua; Wang Huamin
Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer.
Cancer research 2009;69(3):1063-70.
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2008: Liang John J; Wang Hua; Rashid Asif; Tan Tse-Hua; Hwang Rosa F; Hamilton Stanley R; Abbruzzese James L; Evans Douglas B; Wang Huamin
Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):7043-9.
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2008: Onabajo Olusegun O; Seeley Margaret K; Kale Amruta; Qualmann Britta; Kessels Michael; Han Jin; Tan Tse-Hua; Song Wenxia
Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6685-95.
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2007: Chen Min; Guerrero Alan D; Huang Li; Shabier Zainuer; Pan Michael; Tan Tse-Hua; Wang Jin
Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members.
The Journal of biological chemistry 2007;282(46):33888-95.
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2007: Shui Jr-Wen; Boomer Jonathan S; Han Jin; Xu Jun; Dement Gregory A; Zhou Guisheng; Tan Tse-Hua
Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses.
Nature immunology 2007;8(1):84-91.
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2007: Shui Jr-Wen; Hu Mickey C-T; Tan Tse-Hua
Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling.
Molecular and cellular biology 2007;27(1):79-91.
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2006: Wang Jiz-Yuh; Lin Chia-Hua; Yang Chi-Hwa; Tan Tse-Hua; Chen Yi-Rong
Biochemical and biological characterization of a neuroendocrine-associated phosphatase.
Journal of neurochemistry 2006;98(1):89-101.
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2006: Yang Hsin-Sheng; Matthews Connie P; Clair Timothy; Wang Qing; Baker Alyson R; Li Chou-Chi H; Tan Tse-Hua; Colburn Nancy H
Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion.
Molecular and cellular biology 2006;26(4):1297-306.
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2005: Han Jin; Shui Jr-Wen; Zhang Xuejun; Zheng Biao; Han Shuhua; Tan Tse-Hua
HIP-55 is important for T-cell proliferation, cytokine production, and immune responses.
Molecular and cellular biology 2005;25(16):6869-78.
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2005: Boomer Jonathan S; Tan Tse-Hua
Functional interactions of HPK1 with adaptor proteins.
Journal of cellular biochemistry 2005;95(1):34-44.
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2005: Zhang Xiaohong; Ozawa Yukiyasu; Lee Heehyoung; Wen Yu-Der; Tan Tse-Hua; Wadzinski Brian E; Seto Edward
Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.
Genes & development 2005;19(7):827-39.
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2005: MacCorkle Rebecca A; Tan Tse-Hua
Mitogen-activated protein kinases in cell-cycle control.
Cell biochemistry and biophysics 2005;43(3):451-61.
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2004: Zhou Guisheng; Boomer Jonathan S; Tan Tse-Hua
Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.
The Journal of biological chemistry 2004;279(47):49551-61.
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2004: Mihindukulasuriya Kathie A; Zhou Guisheng; Qin Jun; Tan Tse-Hua
Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation.
The Journal of biological chemistry 2004;279(45):46588-94.
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2004: MacCorkle Rebecca A; Tan Tse-Hua
Inhibition of JNK2 disrupts anaphase and produces aneuploidy in mammalian cells.
The Journal of biological chemistry 2004;279(38):40112-21.
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2004: Shui Jr-Wen; Tan Tse-Hua
Germline transmission and efficient DNA recombination in mouse embryonic stem cells mediated by adenoviral-Cre transduction.
Genesis (New York, N.Y. : 2000) 2004;39(3):217-23.
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2003: Han Jin; Kori Rajashree; Shui Jr-Wen; Chen Yi-Rong; Yao Zhengbin; Tan Tse-Hua
The SH3 domain-containing adaptor HIP-55 mediates c-Jun N-terminal kinase activation in T cell receptor signaling.
The Journal of biological chemistry 2003;278(52):52195-202.
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2003: Zheng Biao; Marinova Ekaterina; Han Jin; Tan Tse-Hua; Han Shuhua
Cutting edge: gamma delta T cells provide help to B cells with altered clonotypes and are capable of inducing Ig gene hypermutation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):4979-83.
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2002: Chen Yi-Rong; Han Jin; Kori Rajashree; Kong A-N Tony; Tan Tse-Hua
Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase.
The Journal of biological chemistry 2002;277(42):39334-42.
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2002: Chen Alice J; Zhou Guisheng; Juan Todd; Colicos Suzanne M; Cannon John P; Cabriera-Hansen Maria; Meyer Christian F; Jurecic Roland; Copeland Neal G; Gilbert Debra J; Jenkins Nancy A; Fletcher Fred; Tan Tse-Hua; Belmont John W
The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway.
The Journal of biological chemistry 2002;277(39):36592-601.
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2002: Zhou Guisheng; Mihindukulasuriya Kathie A; MacCorkle-Chosnek Rebecca A; Van Hooser Aaron; Hu Mickey C-T; Brinkley B R; Tan Tse-Hua
Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase.
The Journal of biological chemistry 2002;277(8):6391-8.
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2001: MacCorkle-Chosnek R A; VanHooser A; Goodrich D W; Brinkley B R; Tan T H
Cell cycle regulation of c-Jun N-terminal kinase activity at the centrosomes.
Biochemical and biophysical research communications 2001;289(1):173-80.
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2001: Chen Y R; Kori R; John B; Tan T H
Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis.
Biochemical and biophysical research communications 2001;288(4):981-9.
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2001: Hu M C; Shui J W; Mihindukulasuriya K A; Tan T H
Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase.
Gene 2001;278(1-2):89-99.
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2001: Ling P; Meyer C F; Redmond L P; Shui J W; Davis B; Rich R R; Hu M C; Wange R L; Tan T H
Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.
The Journal of biological chemistry 2001;276(22):18908-14.
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2001: Chen Y R; Shrivastava A; Tan T H
Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate.
Oncogene 2001;20(3):367-74.
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2000: Yu R; Chen C; Mo Y Y; Hebbar V; Owuor E D; Tan T H; Kong A N
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism.
The Journal of biological chemistry 2000;275(51):39907-13.
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2000: Mandlekar S; Yu R; Tan T H; Kong A N
Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells.
Cancer research 2000;60(21):5995-6000.
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2000: Chen Y R; Tan T H
The c-Jun N-terminal kinase pathway and apoptotic signaling (review).
International journal of oncology 2000;16(4):651-62.
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2000: Yu R; Mandlekar S; Tan T H; Kong A N
Activation of p38 and c-Jun N-terminal kinase pathways and induction of apoptosis by chelerythrine do not require inhibition of protein kinase C.
The Journal of biological chemistry 2000;275(13):9612-9.
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2000: Yu R; Mandlekar S; Lei W; Fahl W E; Tan T H; Kong A N
p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-metabolizing enzymes that detoxify carcinogens.
The Journal of biological chemistry 2000;275(4):2322-7.
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1999: Chen Y R; Meyer C F; Ahmed B; Yao Z; Tan T H
Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1).
Oncogene 1999;18(51):7370-7.
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1999: Chen Y R; Zhou G; Tan T H
c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.
Molecular pharmacology 1999;56(6):1271-9.
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1999: Ensenat D; Yao Z; Wang X S; Kori R; Zhou G; Lee S C; Tan T H
A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1.
The Journal of biological chemistry 1999;274(48):33945-50.
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1999: Hu M C; Wang Y p; Qiu W R; Mikhail A; Meyer C F; Tan T H
Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase.
Oncogene 1999;18(40):5514-24.
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1999: Zhou G; Lee S C; Yao Z; Tan T H
Hematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascade.
The Journal of biological chemistry 1999;274(19):13133-8.
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1999: Chen Y R; Tan T H
Lack of correlation in JNK activation and p53-dependent Fas expression induced by apoptotic stimuli.
Biochemical and biophysical research communications 1999;256(3):595-9.
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1999: Hu M C; Wang Y P; Mikhail A; Qiu W R; Tan T H
Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines.
The Journal of biological chemistry 1999;274(11):7095-102.
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1999: Ling P; Yao Z; Meyer C F; Wang X S; Oehrl W; Feller S M; Tan T H
Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase.
Molecular and cellular biology 1999;19(2):1359-68.
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1999: Shtil A A; Mandlekar S; Yu R; Walter R J; Hagen K; Tan T H; Roninson I B; Kong A N
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
Oncogene 1999;18(2):377-84.
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1999: Yao Z; Zhou G; Wang X S; Brown A; Diener K; Gan H; Tan T H
A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.
The Journal of biological chemistry 1999;274(4):2118-25.
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1998: Wang X S; Diener K; Tan T H; Yao Z
MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.
Biochemical and biophysical research communications 1998;253(1):33-7.
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1998: Hu M C; Tang-Oxley Q; Qiu W R; Wang Y P; Mihindukulasuriya K A; Afshar R; Tan T H
Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity.
The Journal of biological chemistry 1998;273(50):33561-5.
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1998: Oehrl W; Kardinal C; Ruf S; Adermann K; Groffen J; Feng G S; Blenis J; Tan T H; Feller S M
The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.
Oncogene 1998;17(15):1893-901.
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1998: Chen Y R; Tan T H
Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin.
Oncogene 1998;17(2):173-8.
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1998: Kong A N; Yu R; Lei W; Mandlekar S; Tan T H; Ucker D S
Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis.
Restorative neurology and neuroscience 1998;12(2-3):63-70.
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1998: Chen Y R; Wang W; Kong A N; Tan T H
Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates.
The Journal of biological chemistry 1998;273(3):1769-75.
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1997: Yao Z; Diener K; Wang X S; Zukowski M; Matsumoto G; Zhou G; Mo R; Sasaki T; Nishina H; Hui C C; Tan T H; Woodgett J P; Penninger J M
Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase.
The Journal of biological chemistry 1997;272(51):32378-83.
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1997: Yu R; Tan T H; Kong A N
Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.
The Journal of biological chemistry 1997;272(46):28962-70.
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1997: Wang W; Zhou G; Hu M C; Yao Z; Tan T H
Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction.
The Journal of biological chemistry 1997;272(36):22771-5.
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1997: Diener K; Wang X S; Chen C; Meyer C F; Keesler G; Zukowski M; Tan T H; Yao Z
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9687-92.
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1996: Chen Y R; Wang X; Templeton D; Davis R J; Tan T H
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation.
The Journal of biological chemistry 1996;271(50):31929-36.
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1996: Wang X S; Diener K; Jannuzzi D; Trollinger D; Tan T H; Lichenstein H; Zukowski M; Yao Z
Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase.
The Journal of biological chemistry 1996;271(49):31607-11.
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1996: Yu R; Shtil A A; Tan T H; Roninson I B; Kong A N
Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis.
Cancer letters 1996;107(1):73-81.
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1996: Hu M C; Qiu W R; Wang X; Meyer C F; Tan T H
Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.
Genes & development 1996;10(18):2251-64.
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1996: Yu R; Jiao J J; Duh J L; Tan T H; Kong A N
Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.
Cancer research 1996;56(13):2954-9.
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1996: Meyer C F; Wang X; Chang C; Templeton D; Tan T H
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation.
The Journal of biological chemistry 1996;271(15):8971-6.
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1996: Chen Y R; Meyer C F; Tan T H
Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis.
The Journal of biological chemistry 1996;271(2):631-4.
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1995: Lai J H; Horvath G; Li Y; Tan T H
Mechanisms of enhanced nuclear translocation of the transcription factors c-Rel and NF-kappa B by CD28 costimulation in human T lymphocytes.
Annals of the New York Academy of Sciences 1995;766():220-3.
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1995: Lai J H; Horvath G; Subleski J; Bruder J; Ghosh P; Tan T H
RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.
Molecular and cellular biology 1995;15(8):4260-71.
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1994: Lai J H; Tan T H
CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin.
The Journal of biological chemistry 1994;269(48):30077-80.
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1994: Bryan R G; Li Y; Lai J H; Van M; Rice N R; Rich R R; Tan T H
Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells.
Molecular and cellular biology 1994;14(12):7933-42.
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1994: Bryan R G; Li Y; Totten R K; Van M; Tan T H; Rich R R
Long-term inositol phosphate release, but not tyrosine kinase activity, correlates with IL-2 secretion and NF-AT induction in anti-CD3-activated peripheral human T lymphocytes.
Cellular immunology 1994;157(1):158-69.
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