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Timothy Tan

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Ying-Xim Tan; Timothy H P Tan; Marvin J-R Lee; Puay-Yoke Tham; Vithiagaran Gunalan; Julian D Druce; Chris Birch; Mike Catton; Nai Yang Fu; Victor C Yu; Yee-Joo Tan
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein.
Shuo Shen; Timothy H P Tan; Yee-Joo Tan
Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV.
Sehaam Khan; Burtram Clintom Fielding; Timothy H P Tan; Chih-Fong Chou; Shuo Shen; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells.

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All Publications

2007: Ying-Xim Tan; Timothy H P Tan; Marvin J-R Lee; Puay-Yoke Tham; Vithiagaran Gunalan; Julian D Druce; Chris Birch; Mike Catton; Nai Yang Fu; Victor C Yu; Yee-Joo Tan
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein.
Journal of virology 2007;81(12):6346-55.
2007: Shuo Shen; Timothy H P Tan; Yee-Joo Tan
Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS CoV.
Methods in molecular biology (Clifton, N.J.) 2007;379():127-35.
2006: Sehaam Khan; Burtram Clintom Fielding; Timothy H P Tan; Chih-Fong Chou; Shuo Shen; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells.
Virus research 2006;122(1-2):20-7.
2006: Chih-Fong Chou; Chay Boon Loh; Yik Khoon Foo; Shuo Shen; Burtram Clintom Fielding; Timothy H P Tan; Sehaam Khan; Yue Wang; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan; Jianlin Fu
ACE2 orthologues in non-mammalian vertebrates (Danio, Gallus, Fugu, Tetraodon and Xenopus).
Gene 2006;377():46-55.
2006: Burtram Clintom Fielding; Vithiagaran Gunalan; Timothy H P Tan; Chih-Fong Chou; Shuo Shen; Sehaam Khan; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT.
Biochemical and biophysical research communications 2006;343(4):1201-8.
2006: Kuo-Ming Lip; Shuo Shen; Xiaoming Yang; Choong-Tat Keng; Aihua Zhang; Hsueh-Ling Janice Oh; Zhi-Hong Li; Le-Ann Hwang; Chih-Fong Chou; Burtram Clintom Fielding; Timothy H P Tan; Josef Mayrhofer; Falko G Falkner; Jianlin Fu; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.
Journal of virology 2006;80(2):941-50.
2005: Yee-Joo Tan; Puay-Yoke Tham; Daphne Z L Chan; Chih-Fong Chou; Shuo Shen; Burtram Clintom Fielding; Timothy H P Tan; Seng Gee Lim; Wanjin Hong
The severe acute respiratory syndrome coronavirus 3a protein up-regulates expression of fibrinogen in lung epithelial cells.
Journal of virology 2005;79(15):10083-7.
2005: Fabien Charrière; Timothy H P Tan; André Schneider
Mitochondrial initiation factor 2 of Trypanosoma brucei binds imported formylated elongator-type tRNA(Met).
The Journal of biological chemistry 2005;280(16):15659-65.
2005: Choong-Tat Keng; Aihua Zhang; Shuo Shen; Kuo-Ming Lip; Burtram Clintom Fielding; Timothy H P Tan; Chih-Fong Chou; Chay Boon Loh; Sifang Wang; Jianlin Fu; Xiaoming Yang; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: implications for the development of vaccines and antiviral agents.
Journal of virology 2005;79(6):3289-96.
2005: Timothy H P Tan; Timothy Barkham; Burtram Clintom Fielding; Chih-Fong Chou; Shuo Shen; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Genetic lesions within the 3a gene of SARS-CoV.
Virology journal 2005;2():51.
2005: Chih-Fong Chou; Shuo Shen; Yee-Joo Tan; Burtram Clintom Fielding; Timothy H P Tan; Jianlin Fu; Qiurong Xu; Seng Gee Lim; Wanjin Hong
A novel cell-based binding assay system reconstituting interaction between SARS-CoV S protein and its cellular receptor.
Journal of virological methods 2005;123(1):41-8.
2004: Yee-Joo Tan; Burtram Clintom Fielding; Phuay-Yee Goh; Shuo Shen; Timothy H P Tan; Seng Gee Lim; Wanjin Hong
Overexpression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway.
Journal of virology 2004;78(24):14043-7.
2004: Burtram Clintom Fielding; Yee-Joo Tan; Shen Shuo; Timothy H P Tan; Eng Eong Ooi; Seng Gee Lim; Wanjin Hong; Phuay-Yee Goh
Characterization of a unique group-specific protein (U122) of the severe acute respiratory syndrome coronavirus.
Journal of virology 2004;78(14):7311-8.
2004: Yee-Joo Tan; Eileen Teng; Shuo Shen; Timothy H P Tan; Phuay-Yee Goh; Burtram Clintom Fielding; Eng Eong Ooi; Hwee Cheng Tan; Seng Gee Lim; Wanjin Hong
A novel severe acute respiratory syndrome coronavirus protein, U274, is transported to the cell surface and undergoes endocytosis.
Journal of virology 2004;78(13):6723-34.
2002: Timothy H P Tan; Roland Pach; Anne Crausaz; Alasdair Ivens; André Schneider
tRNAs in Trypanosoma brucei: genomic organization, expression, and mitochondrial import.
Molecular and cellular biology 2002;22(11):3707-17.
2002: Timothy H P Tan; Natacha Bochud-Allemann; Elke K Horn; Andre Schneider
Eukaryotic-type elongator tRNAMet of Trypanosoma brucei becomes formylated after import into mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1152-7.