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Wei Tan

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Yiru Guo; Qianhong Li; Wei Tan; Wen-Jian Wu; Xiaoping Zhu; Michael P Flaherty; Roberto Bolli
Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of infarct size in 1,074 mice.
Yiru Guo; Yiming Huang; Suzanne T Ildstad; Qianhong Li; Santosh K Sanganalmath; Wei Tan; Wenjian Wu; Xiaoping Zhu; Roberto Bolli
Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury.
Yiru Guo; Steven P Jones; Qianhong Li; Shuh Narumiya; Gregg Rokosh; Wei Tan; Deepali Nivas Tukaye; Wen-Jian Wu; Xiaoping Zhu; Michael Book; Roberto Bolli
The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning.

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2012: Yiru Guo; Qianhong Li; Wei Tan; Wen-Jian Wu; Xiaoping Zhu; Michael P Flaherty; Roberto Bolli
Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of infarct size in 1,074 mice.
Basic research in cardiology 2012;107(5):288.
2012: Yiru Guo; Yiming Huang; Suzanne T Ildstad; Qianhong Li; Santosh K Sanganalmath; Wei Tan; Wenjian Wu; Xiaoping Zhu; Roberto Bolli
Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury.
Basic research in cardiology 2012;107(2):253.
2012: Yiru Guo; Steven P Jones; Qianhong Li; Shuh Narumiya; Gregg Rokosh; Wei Tan; Deepali Nivas Tukaye; Wen-Jian Wu; Xiaoping Zhu; Michael Book; Roberto Bolli
The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning.
PloS one 2012;7(7):e41178.
2011: Qianhong Li; Li Luo; Qinghui Ou; Wei Tan; Wen-Jian Wu; Fangping Yuan; Xiaoping Zhu; Ning Chen; Buddhadeb Dawn; Yiru Guo; Gregory N Hunt; Roberto Bolli
Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences.
Basic research in cardiology 2011;106(6):1367-77.
2011: Qianhong Li; Li Luo; Erin O'Brien; Qinghui Ou; Wei Tan; Wen-Jian Wu; Fangping Yuan; Xiaoping Zhu; Ning Chen; Buddhadeb Dawn; Yiru Guo; Roberto Bolli
Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences.
Basic research in cardiology 2011;106(6):1355-66.
2009: Qianhong Li; Yiru Guo; Qinghui Ou; Chuanjue Cui; Wen-Jian Wu; Wei Tan; Xiaoping Zhu; Lilibeth B Lanceta; Santosh K Sanganalmath; Buddhadeb Dawn; Ken Shinmura; Gregg Rokosh; Shuyan Wang; Roberto Bolli
Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway.
Circulation 2009;120(13):1222-30.
2008: Yiru Guo; Qianhong Li; Wen-Jian Wu; Wei Tan; Xiaoping Zhu; Jingyao Mu; Roberto Bolli
Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse.
Journal of molecular and cellular cardiology 2008;44(3):496-501.
2007: Qianhong Li; Yiru Guo; Wei Tan; Qinghui Ou; Wen-Jian Wu; Diana Sturza; Buddhadeb Dawn; Greg Hunt; Chuanjue Cui; Roberto Bolli
Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway.
Circulation 2007;116(14):1577-84.
2007: Xiaofeng Hu; Shujing Dai; Wen-Jian Wu; Wei Tan; Xiaoping Zhu; Jingyao Mu; Yiru Guo; Roberto Bolli; Gregg Rokosh
Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis.
Circulation 2007;116(6):654-63.
2007: Adam B Stein; Roberto Bolli; Yiru Guo; Ou-Li Wang; Wei Tan; Wen-Jian Wu; Xiaoping Zhu; Yanqing Zhu; Yu-Ting Xuan
The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis.
Journal of molecular and cellular cardiology 2007;42(6):1075-85.
2006: Qianhong Li; Yiru Guo; Wei Tan; Adam B Stein; Buddhadeb Dawn; Wen-Jian Wu; Xiaoping Zhu; Xiaoqin Lu; Xiaoming Xu; Tariq Siddiqui; Sumit Tiwari; Roberto Bolli
Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequences.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H584-9.
2005: Yiru Guo; Adam B Stein; Wen-Jian Wu; Xiaoping Zhu; Wei Tan; Qianhong Li; Roberto Bolli
Late preconditioning induced by NO donors, adenosine A1 receptor agonists, and delta1-opioid receptor agonists is mediated by iNOS.
American journal of physiology. Heart and circulatory physiology 2005;289(5):H2251-7.
2005: Adam B Stein; Yiru Guo; Wei Tan; Wen-Jian Wu; Xiaoping Zhu; Qianhong Li; Cheng Luo; Buddhadeb Dawn; Tony R Johnson; Roberto Motterlini; Roberto Bolli
Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction.
Journal of molecular and cellular cardiology 2005;38(1):127-34.
2004: Buddhadeb Dawn; Yu-Ting Xuan; Yiru Guo; Arash Rezazadeh; Adam B Stein; Greg Hunt; Wen-Jian Wu; Wei Tan; Roberto Bolli
IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2.
Cardiovascular research 2004;64(1):61-71.
2004: Buddhadeb Dawn; Yiru Guo; Arash Rezazadeh; Ou-Li Wang; Adam B Stein; Greg Hunt; Jai Varma; Yu-Ting Xuan; Wen-Jian Wu; Wei Tan; Xiaoping Zhu; Roberto Bolli
Tumor necrosis factor-alpha does not modulate ischemia/reperfusion injury in naïve myocardium but is essential for the development of late preconditioning.
Journal of molecular and cellular cardiology 2004;37(1):51-61.
2004: Yiru Guo; Adam B Stein; Wen-Jian Wu; Wei Tan; Xiaoping Zhu; Qian-Hong Li; Buddhadeb Dawn; Roberto Motterlini; Roberto Bolli
Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo.
American journal of physiology. Heart and circulatory physiology 2004;286(5):H1649-53.