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Tadashi Tanabe

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Yasuo Kunugiza; Naruya Tomita; Yoshiaki Taniyama; Tetsuya Tomita; Mariana Kiomy Osako; Katsuto Tamai; Tadashi Tanabe; Yasufumi Kaneda; Hideki Yoshikawa; Ryuichi Morishita
Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet.
Masamichi Ono; Yoshiki Sawa; Norihide Fukushima; Hitoshi Suhara; Toshikazu Nakamura; Chieko Yokoyama; Tadashi Tanabe; Hikaru Matsuda
Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats.
Masayuki Wada; Chieko Yokoyama; Toshihisa Hatae; Manabu Shimonishi; Masahiko Nakamura; Yoshio Imai; Volker Ullrich; Tadashi Tanabe
Purification and characterization of recombinant human prostacyclin synthase.

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All Publications

2006: Yasuo Kunugiza; Naruya Tomita; Yoshiaki Taniyama; Tetsuya Tomita; Mariana Kiomy Osako; Katsuto Tamai; Tadashi Tanabe; Yasufumi Kaneda; Hideki Yoshikawa; Ryuichi Morishita
Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet.
Gene therapy 2006;13(15):1143-52.
2004: Masamichi Ono; Yoshiki Sawa; Norihide Fukushima; Hitoshi Suhara; Toshikazu Nakamura; Chieko Yokoyama; Tadashi Tanabe; Hikaru Matsuda
Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2004;26(6):1092-7.
2004: Masayuki Wada; Chieko Yokoyama; Toshihisa Hatae; Manabu Shimonishi; Masahiko Nakamura; Yoshio Imai; Volker Ullrich; Tadashi Tanabe
Purification and characterization of recombinant human prostacyclin synthase.
Journal of biochemistry 2004;135(4):455-63.
2003: Hiromi Koike; Ryuichi Morishita; Sota Iguchi; Motokuni Aoki; Kunio Matsumoto; Toshikazu Nakamura; Chieko Yokoyama; Tadashi Tanabe; Toshio Ogihara; Yasufumi Kaneda
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):779-81.
2002: Chieko Yokoyama; Tomoko Yabuki; Manabu Shimonishi; Masayuki Wada; Toshihisa Hatae; Susumu Ohkawara; Junji Takeda; Taroh Kinoshita; Masaru Okabe; Tadashi Tanabe
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction.
Circulation 2002;106(18):2397-403.
2002: Hiroaki Naraba; Chieko Yokoyama; Naomi Tago; Makoto Murakami; Ichiro Kudo; Mai Fueki; Sachiko Oh-Ishi; Tadashi Tanabe
Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.
The Journal of biological chemistry 2002;277(32):28601-8.
2002: Tadashi Tanabe; Norimitsu Tohnai
Cyclooxygenase isozymes and their gene structures and expression.
Prostaglandins & other lipid mediators 2002;68-69():95-114.
2002: Toshihisa Hatae; Tadashi Tanabe
[PPARs and signal transduction of prostaglandins].
Seikagaku. The Journal of Japanese Biochemical Society 2002;74(7):551-4.
2002: Hitoshi Suhara; Yoshiki Sawa; Norihide Fukushima; Koji Kagisaki; Chieko Yokoyama; Tadashi Tanabe; Shigeaki Ohtake; Hikaru Matsuda
Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats.
The Journal of thoracic and cardiovascular surgery 2002;123(5):855-61.
2002: Tomohiko Okuda; Toshiki Sumiya; Ken-ichi Mizutani; Naomi Tago; Toshiyuki Miyata; Tadashi Tanabe; Hisao Kato; Tomohiro Katsuya; Jitsuo Higaki; Toshio Ogihara; Yasuyuki Tsujita; Naoharu Iwai; Ken-ichi Muzutani; Hiroshi Kato
Analyses of differential gene expression in genetic hypertensive rats by microarray.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(2):249-55.
2002: Gen Nakauchi; Yoshiaki Inaki; Shiho Kitaoka; Chieko Yokoyama; Tadashi Tanabe
Application of L-cystein derivative to DNA microarray.
Nucleic acids research. Supplement (2001) 2002;(2):257-8.
2002: Susumu Ohkawara; Chieko Yokoyama; Manabu Shimonishi; Tadashi Tanabe
Analysis of the transcriptional regulation of mouse prostacyclin synthase gene.
Advances in experimental medicine and biology 2002;507():281-6.
2002: Chieko Yokoyama; Tatemi Todaka; Hiroji Yanamoto; Toshihisa Hatae; Shuntaro Hara; Manabu Shimonishi; Susumu Ohkawara; Masayuki Wada; Tadashi Tanabe
Effects of overexpression of prostacyclin synthase in vascular smooth muscle cells.
Advances in experimental medicine and biology 2002;507():275-80.
2002: Ken-ichi Mizutani; Ken Sugimoto; Tomohiko Okuda; Tomohiro Katsuya; Toshiyuki Miyata; Tadashi Tanabe; Jitsuo Higaki; Toshio Ogihara; Yukio Yamori; Yasuyuki Tsujita; Naomi Tago; Naoharu Iwai
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(1):135-40.
2001: Toshihisa Hatae; Masayuki Wada; Chieko Yokoyama; Manabu Shimonishi; Tadashi Tanabe
Prostacyclin-dependent apoptosis mediated by PPAR delta.
The Journal of biological chemistry 2001;276(49):46260-7.
2001: Shiho Kitaoka; Yoshiaki Inaki; Hisato Maruoka; Norimitsu Tohnai; Toshihisa Hatae; Tadashi Tanabe
Transfection of fluorescent probed antisense compounds: L-cysteine derivatives of nucleic acid bases.
Nucleic acids research. Supplement (2001) 2001;(1):135-6.
2001: Hisato Maruoka; Shiho Kitaoka; Norimitsu Tohnai; Yoshiaki Inaki; Tadashi Tanabe
Study about the inhibition of L-cysteine derivatives of nucleic acid bases in protein production.
Nucleic acids research. Supplement (2001) 2001;(1):97-8.
2000: Susumu Ohkawara; Manabu Shimonishi; Tadashi Tanabe; Chieko Yokoyama
Cloning and characterization of 5'-flanking region of mouse prostacyclin synthase gene.
Biochimica et biophysica acta 2000;1494(1-2):155-61.
2000: Noritoshi Nagaya; Chieko Yokoyama; Shingo Kyotani; Manabu Shimonishi; Ryuichi Morishita; Masaaki Uematsu; T Nishikimi; Norifumi Nakanishi; Toshio Ogihara; M Yamagishi; Kunio Miyatake; Yasufumi Kaneda; Tadashi Tanabe
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.
Circulation 2000;102(16):2005-10.
2000: Hiroyasu Inoue; Tadashi Tanabe; Kazuhiko Umesono
Feedback control of cyclooxygenase-2 expression through PPARgamma.
The Journal of biological chemistry 2000;275(36):28028-32.
2000: Hisato Maruoka; Shiho Kitaoka; Norimitsu Tohnai; Yoshiaki Inaki; Toshihisa Hatae; Tadashi Tanabe
The behavior and effect of isopoly (S-carboxymethyl-L-cysteine) derivatives of nucleic acid bases.
Nucleic acids symposium series 2000;(44):195-6.
1999: Tatemi Todaka; Chieko Yokoyama; Hiroji Yanamoto; Nobuo Hashimoto; Izumi Nagata; T Tsukahara; Shuntaro Hara; Toshihisa Hatae; Ryuichi Morishita; Motokuni Aoki; Toshio Ogihara; Yasufumi Kaneda; Tadashi Tanabe
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.
Stroke; a journal of cerebral circulation 1999;30(2):419-26.
1999: Hiroyasu Inoue; Kazuhiko Umesono; T Nishimori; Y Hirata; Tadashi Tanabe
Glucocorticoid-mediated suppression of the promoter activity of the cyclooxygenase-2 gene is modulated by expression of its receptor in vascular endothelial cells.
Biochemical and biophysical research communications 1999;254(2):292-8.
1999: Shiho Kitaoka; Norimitsu Tohnai; Yoshiaki Inaki; Toshihisa Hatae; Tadashi Tanabe
Fluorescent probe and permeability to cells of isopoly (S-carboxymethyl-L-cysteine) derivative of nucleic acid bases.
Nucleic acids symposium series 1999;(42):91-2.
1998: Manabu Shimonishi; S Kuwamoto; Hiroyasu Inoue; Ron Wever; Takashi Ohshiro; Yoshikazu Izumi; Tadashi Tanabe
Cloning and expression of the gene for a vanadium-dependent bromoperoxidase from a marine macro-alga, Corallina pilulifera.
FEBS letters 1998;428(1-2):105-10.
1998: Hiroyasu Inoue; Tadashi Tanabe
Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells.
Biochemical and biophysical research communications 1998;244(1):143-8.
1997: S Kuwamoto; Hiroyasu Inoue; Y Tone; Yoshikazu Izumi; Tadashi Tanabe
Inverse gene expression of prostacyclin and thromboxane synthases in resident and activated peritoneal macrophages.
FEBS letters 1997;409(2):242-6.
1997: Y Tone; Hiroyasu Inoue; Shuntaro Hara; Chieko Yokoyama; Toshihisa Hatae; H Oida; S Narumiya; R Shigemoto; S Yukawa; Tadashi Tanabe
The regional distribution and cellular localization of mRNA encoding rat prostacyclin synthase.
European journal of cell biology 1997;72(3):268-77.
1997: Tadashi Tanabe; Shuntaro Hara; A Miyata; R Brugger; Y Ullrich
Molecular cloning of prostacyclin synthase from bovine endothelial cells.
Advances in experimental medicine and biology 1997;400A():183-7.
1997: Hiroyasu Inoue; Tadashi Tanabe
Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene in vascular endothelial cells.
Advances in experimental medicine and biology 1997;407():139-44.
1996: Chieko Yokoyama; T Yabuki; H Inoue; Yoshinori Tone; Shuntaro Hara; T Hatae; M Nagata; E I Takahashi; Tadashi Tanabe
Human gene encoding prostacyclin synthase (PTGIS): genomic organization, chromosomal localization, and promoter activity.
Genomics 1996;36(2):296-304.
1996: T Hatae; Shuntaro Hara; Chieko Yokoyama; T Yabuki; H Inoue; V Ullrich; Tadashi Tanabe
Site-directed mutagenesis of human prostacyclin synthase: Alteration of Cys441 of the Cys-pocket, and Glu347 and Arg350 of the EXXR motif.
FEBS letters 1996;389(3):268-72.
1995: Shuntaro Hara; Ryuichi Morishita; Yoshinori Tone; Chieko Yokoyama; H Inoue; Yasufumi Kaneda; Toshio Ogihara; Tadashi Tanabe
Overexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cells.
Biochemical and biophysical research communications 1995;216(3):862-7.
1995: H Inoue; Chieko Yokoyama; Shuntaro Hara; Yoshinori Tone; Tadashi Tanabe
Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element.
The Journal of biological chemistry 1995;270(42):24965-71.
1995: Tadashi Tanabe; V Ullrich
Prostacyclin and thromboxane synthases.
Journal of lipid mediators and cell signalling 1995;12(2-3):243-55.
1995: T Nanayama; Shuntaro Hara; H Inoue; Chieko Yokoyama; Tadashi Tanabe
Regulation of two isozymes of prostaglandin endoperoxide synthase and thromboxane synthase in human monoblastoid cell line U937.
Prostaglandins 1995;49(6):371-82.
1995: Tadashi Tanabe; A Miyata; T Nanayama; Yoshinori Tone; H Ihara; H Toh; E Takahashi; V Ullrich
Human genes for prostaglandin endoperoxide synthase-2, thromboxane synthase and prostacyclin synthase.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():133-5.
1995: Shuntaro Hara; A Miyata; Chieko Yokoyama; R Brugger; F Lottspeich; V Ullrich; Tadashi Tanabe
Molecular cloning and expression of prostacyclin synthase from endothelial cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():121-3.
1995: H Inoue; T Kosaka; A Miyata; Shuntaro Hara; Chieko Yokoyama; T Nanayama; Tadashi Tanabe
Structure and expression of the human prostaglandin endoperoxide synthase 2 gene.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():109-11.
1994: A Miyata; Chieko Yokoyama; H Ihara; S Bandoh; O Takeda; E Takahashi; Tadashi Tanabe
Characterization of the human gene (TBXAS1) encoding thromboxane synthase.
European journal of biochemistry / FEBS 1994;224(2):273-9.
1994: H Inoue; T Nanayama; Shuntaro Hara; Chieko Yokoyama; Tadashi Tanabe
The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells.
FEBS letters 1994;350(1):51-4.
1994: Shuntaro Hara; A Miyata; Chieko Yokoyama; H Inoue; R Brugger; F Lottspeich; V Ullrich; Tadashi Tanabe
Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells.
The Journal of biological chemistry 1994;269(31):19897-903.
1994: T Yoshida; K Yamaguchi; T Hagishita; Toshio Mitsunaga; A Miyata; Tadashi Tanabe; H Toh; T Ohshiro; M Shimao; Y Izumi
Cloning and expression of the gene for hydroxypyruvate reductase (D-glycerate dehydrogenase from an obligate methylotroph Hyphomicrobium methylovorum GM2.
European journal of biochemistry / FEBS 1994;223(3):727-32.
1994: A Miyata; Shuntaro Hara; Chieko Yokoyama; H Inoue; V Ullrich; Tadashi Tanabe
Molecular cloning and expression of human prostacyclin synthase.
Biochemical and biophysical research communications 1994;200(3):1728-34.
1994: T Kosaka; A Miyata; H Ihara; S Hara; T Sugimoto; O Takeda; E Takahashi; Tadashi Tanabe
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2.
European journal of biochemistry / FEBS 1994;221(3):889-97.
1994: Yoshinori Tone; A Miyata; Shuntaro Hara; S Yukawa; Tadashi Tanabe
Abundant expression of thromboxane synthase in rat macrophages.
FEBS letters 1994;340(3):241-4.
1993: Y Izumi; T Yoshida; S S Miyazaki; Toshio Mitsunaga; T Ohshiro; M Shimao; A Miyata; Tadashi Tanabe
L-serine production by a methylotroph and its related enzymes.
Applied microbiology and biotechnology 1993;39(4-5):427-32.
1993: A Miyata; T Yoshida; K Yamaguchi; Chieko Yokoyama; Tadashi Tanabe; H Toh; Toshio Mitsunaga; Y Izumi
Molecular cloning and expression of the gene for serine hydroxymethyltransferase from an obligate methylotroph Hyphomicrobium methylovorum GM2.
European journal of biochemistry / FEBS 1993;212(3):745-50.
1993: Tadashi Tanabe; Chieko Yokoyama; A Miyata; H Ihara; T Kosaka; K Suzuki; Y Nishikawa; T Yoshimoto; S Yamamoto; R Nüsing
Molecular cloning and expression of human thromboxane synthase.
Journal of lipid mediators 1993;6(1-3):139-44.
1993: Chieko Yokoyama; A Miyata; K Suzuki; Y Nishikawa; T Yoshimoto; S Yamamoto; R Nüsing; V Ullrich; Tadashi Tanabe
Expression of human thromboxane synthase using a baculovirus system.
FEBS letters 1993;318(1):91-4.
1992: H Ihara; Chieko Yokoyama; A Miyata; T Kosaka; R Nüsing; V Ullrich; Tadashi Tanabe
Induction of thromboxane synthase and prostaglandin endoperoxide synthase mRNAs in human erythroleukemia cells by phorbol ester.
FEBS letters 1992;306(2-3):161-4.
1991: Chieko Yokoyama; A Miyata; H Ihara; V Ullrich; Tadashi Tanabe
Molecular cloning of human platelet thromboxane A synthase.
Biochemical and biophysical research communications 1991;178(3):1479-84.
1991: Chieko Yokoyama; H Toh; A Miyata; Tadashi Tanabe
Cloning and characterization of human cyclooxygenase gene and primary structure of the enzyme.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():61-4.
1989: Chieko Yokoyama; Tadashi Tanabe
Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme.
Biochemical and biophysical research communications 1989;165(2):888-94.