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Issei Tanaka

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Hiroyuki Koshiyama; Yoshihiro Ogawa; Kiyoshi Tanaka; Issei Tanaka
Integrated network systems and evolutionary developmental endocrinology.
Tetsuya Nagae; Kazuhiro J Mori; Masashi Mukoyama; Masato Kasahara; Hideki Yokoi; Takayoshi Suganami; Kazutomo Sawai; Tetsuro Yoshioka; Masao Koshikawa; Yoshihiko Saito; Yoshihiro Ogawa; T Kuwabara; Issei Tanaka; Akira Sugawara; Takashi Kuwahara; Kazuwa Nakao
Adrenomedullin inhibits connective tissue growth factor expression, extracellular signal-regulated kinase activation and renal fibrosis.
Hirofumi Makino; Masashi Mukoyama; Kazuhiro J Mori; Takayoshi Suganami; Masato Kasahara; Kensei Yahata; Tetsuya Nagae; Hideki Yokoi; Kazutomo Sawai; Yoshihiro Ogawa; Shinichi Suga; Yasunao Yoshimasa; Akira Sugawara; Issei Tanaka; Kazuwa Nakao
Transgenic overexpression of brain natriuretic peptide prevents the progression of diabetic nephropathy in mice.

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All Publications

2010: Hiroyuki Koshiyama; Yoshihiro Ogawa; Kiyoshi Tanaka; Issei Tanaka
Integrated network systems and evolutionary developmental endocrinology.
Medical hypotheses 2010;74(1):132-8.
2008: Tetsuya Nagae; Kazuhiro J Mori; Masashi Mukoyama; Masato Kasahara; Hideki Yokoi; Takayoshi Suganami; Kazutomo Sawai; Tetsuro Yoshioka; Masao Koshikawa; Yoshihiko Saito; Yoshihiro Ogawa; T Kuwabara; Issei Tanaka; Akira Sugawara; Takashi Kuwahara; Kazuwa Nakao
Adrenomedullin inhibits connective tissue growth factor expression, extracellular signal-regulated kinase activation and renal fibrosis.
Kidney international 2008;74(1):70-80.
2006: Hirofumi Makino; Masashi Mukoyama; Kazuhiro J Mori; Takayoshi Suganami; Masato Kasahara; Kensei Yahata; Tetsuya Nagae; Hideki Yokoi; Kazutomo Sawai; Yoshihiro Ogawa; Shinichi Suga; Yasunao Yoshimasa; Akira Sugawara; Issei Tanaka; Kazuwa Nakao
Transgenic overexpression of brain natriuretic peptide prevents the progression of diabetic nephropathy in mice.
Diabetologia 2006;49(10):2514-24.
2003: Takayoshi Suganami; Kiyoshi Mori; Issei Tanaka; Masashi Mukoyama; Akira Sugawara; Hisashi Makino; Shigeo Muro; Kensei Yahata; Shuichi Ohuchida; Takayuki Maruyama; Shuh Narumiya; Kazuwa Nakao
Role of prostaglandin E receptor EP1 subtype in the development of renal injury in genetically hypertensive rats.
Hypertension 2003;42(6):1183-90.
2003: Kazutomo Sawai; Kiyoshi Mori; Masashi Mukoyama; Akira Sugawara; Takayoshi Suganami; Masao Koshikawa; Kensei Yahata; Hisashi Makino; Tetsuya Nagae; Yuriko Fujinaga; Hideki Yokoi; Tetsuro Yoshioka; Akihiro Yoshimoto; Issei Tanaka; Kazuwa Nakao
Angiogenic protein Cyr61 is expressed by podocytes in anti-Thy-1 glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2003;14(5):1154-63.
2003: Hisashi Makino; Masashi Mukoyama; Akira Sugawara; Kiyoshi Mori; Takayoshi Suganami; Kensei Yahata; Yuriko Fujinaga; Hideki Yokoi; Issei Tanaka; Kazuwa Nakao
Roles of connective tissue growth factor and prostanoids in early streptozotocin-induced diabetic rat kidney: the effect of aspirin treatment.
Clinical and experimental nephrology 2003;7(1):33-40.
2002: Hisashi Makino; Issei Tanaka; Masashi Mukoyama; Akira Sugawara; Kiyoshi Mori; Shigeo Muro; Takayoshi Suganami; Kensei Yahata; Rieko Ishibashi; Shuichi Ohuchida; Takayuki Maruyama; Shuh Narumiya; Kazuwa Nakao
Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist.
Journal of the American Society of Nephrology : JASN 2002;13(7):1757-65.
2002: Hideki Yokoi; Masashi Mukoyama; Akira Sugawara; Kiyoshi Mori; Tetsuya Nagae; Hisashi Makino; Takayoshi Suganami; Kensei Yahata; Yuriko Fujinaga; Issei Tanaka; Kazuwa Nakao
Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis.
American journal of physiology. Renal physiology 2002;282(5):F933-42.
2002: Masahisa Goto; Masashi Mukoyama; Akira Sugawara; Takayoshi Suganami; Masato Kasahara; Kensei Yahata; Hisashi Makino; Shinichi Suga; Issei Tanaka; Kazuwa Nakao
Expression and role of angiotensin II type 2 receptor in the kidney and mesangial cells of spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(1):125-33.
2001: Takayoshi Suganami; Masashi Mukoyama; Akira Sugawara; Kazuhiro J Mori; Tetsuya Nagae; Masato Kasahara; Kensei Yahata; Hirofumi Makino; Yuriko Fujinaga; Yoshihiro Ogawa; Issei Tanaka; Kazuwa Nakao
Overexpression of brain natriuretic peptide in mice ameliorates immune-mediated renal injury.
Journal of the American Society of Nephrology : JASN 2001;12(12):2652-63.
2001: Masashi Mukoyama; Akira Sugawara; Tetsuya Nagae; Kazuhiro J Mori; H Murabe; Hiroaki Itoh; Issei Tanaka; Kazuwa Nakao
Role of adrenomedullin and its receptor system in renal pathophysiology.
Peptides 2001;22(11):1925-31.
2001: Hideki Yokoi; Akira Sugawara; Masashi Mukoyama; Kazuhiro J Mori; Hirofumi Makino; Takayoshi Suganami; Tetsuya Nagae; Kensei Yahata; Yuriko Fujinaga; Issei Tanaka; Kazuwa Nakao
Role of connective tissue growth factor in profibrotic action of transforming growth factor-beta: a potential target for preventing renal fibrosis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;38(4 Suppl 1):S134-8.
2001: Takayoshi Suganami; Issei Tanaka; Masashi Mukoyama; M Kotani; Shigeo Muro; Kazuhiro J Mori; Masahisa Goto; Rieko Ishibashi; Masato Kasahara; Kensei Yahata; Hirofumi Makino; Akira Sugawara; Kazuwa Nakao
Altered growth response to prostaglandin E2 and its receptor signaling in mesangial cells from stroke-prone spontaneously hypertensive rats.
Journal of hypertension 2001;19(6):1095-103.
2001: M Nakagawa; Issei Tanaka; Masashi Mukoyama; Shinichi Suga; Yoshihiro Ogawa; Naohisa Tamura; Rieko Ishibashi; Masahisa Goto; O Nakagawa; Akira Sugawara; Kazuwa Nakao
Monoclonal antibody against brain natriuretic peptide and characterization of brain natriuretic peptide-transgenic mice.
Journal of hypertension 2001;19(3):475-83.
2000: M Kotani; Issei Tanaka; Yoshihiro Ogawa; Takayoshi Suganami; Toshio Matsumoto; Shigeo Muro; Y Yamamoto; Akira Sugawara; Yasunao Yoshimasa; Norimasa Sagawa; Shuh Narumiya; Kazuwa Nakao
Multiple signal transduction pathways through two prostaglandin E receptor EP3 subtype isoforms expressed in human uterus.
The Journal of clinical endocrinology and metabolism 2000;85(11):4315-22.
2000: Masato Kasahara; Masashi Mukoyama; Akira Sugawara; Hirofumi Makino; Takayoshi Suganami; Yoshihiro Ogawa; M Nakagawa; Kensei Yahata; Masahisa Goto; Rieko Ishibashi; Naohisa Tamura; Issei Tanaka; Kazuwa Nakao
Ameliorated glomerular injury in mice overexpressing brain natriuretic peptide with renal ablation.
Journal of the American Society of Nephrology : JASN 2000;11(9):1691-701.
2000: Shigeo Muro; Issei Tanaka; Takeshi Usui; M Kotani; S Koide; Masashi Mukoyama; J Fukata; Hiroaki Itoh; Shuh Narumiya; M Kawata; Kazuwa Nakao
Expression of prostaglandin E receptor EP4 subtype in rat adrenal zona glomerulosa: involvement in aldosterone release.
Endocrine journal 2000;47(4):429-36.
2000: Tetsuya Nagae; Masashi Mukoyama; Akira Sugawara; Kazuhiro J Mori; Kensei Yahata; Masato Kasahara; Takayoshi Suganami; Hirofumi Makino; Yuriko Fujinaga; Tetsuro Yoshioka; Issei Tanaka; Kazuwa Nakao
Rat receptor-activity-modifying proteins (RAMPs) for adrenomedullin/CGRP receptor: cloning and upregulation in obstructive nephropathy.
Biochemical and biophysical research communications 2000;270(1):89-93.
2000: Takeshi Usui; Yoshio Nakamura; Hiroshi Mizuta; H Murabe; Shigeo Muro; Michio Suda; Kiyoji Tanaka; Issei Tanaka; Akira Shimatsu; Kazuwa Nakao
Functional significance of prop-1 gene expression in pituitary adenomas.
Endocrine journal 2000;47 Suppl():S85-9.
2000: Michio Suda; Kiyoji Tanaka; Yoko Sakuma; Akihiro Yasoda; Ami Ozasa; J Fukata; Issei Tanaka; Shuh Narumiya; Kazuwa Nakao
Prostaglandin E(2) (PGE(2)) induces the c-fos and c-jun expressions via the EP(1) subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells.
Calcified tissue international 2000;66(3):217-23.
2000: Yoko Sakuma; Kiyoji Tanaka; Michio Suda; Akihiro Yasoda; Koshi Natsui; Issei Tanaka; Fumitaka Ushikubi; Shuh Narumiya; Eri Segi; Yukihiko Sugimoto; Atsushi Ichikawa; Kazuwa Nakao
Crucial involvement of the EP4 subtype of prostaglandin E receptor in osteoclast formation by proinflammatory cytokines and lipopolysaccharide.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(2):218-27.
1999: Kensei Yahata; Issei Tanaka; M Kotani; Masashi Mukoyama; Y Ogawa; M Goto; M Nakagawa; Akira Sugawara; Keiichi Tanaka; A Shimatsu; Kazuwa Nakao
Identification of a novel R642C mutation in Na/Cl cotransporter with Gitelman's syndrome.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1999;34(5):845-53.
1999: Rieko Ishibashi; Issei Tanaka; M Kotani; Shigeo Muro; Masahisa Goto; Akira Sugawara; Masashi Mukoyama; Yukihiko Sugimoto; Atsushi Ichikawa; Shuh Narumiya; Kazuwa Nakao
Roles of prostaglandin E receptors in mesangial cells under high-glucose conditions.
Kidney international 1999;56(2):589-600.
1999: Yoshio Nakamura; Takeshi Usui; Hiroshi Mizuta; H Murabe; Shigeo Muro; Michio Suda; Kiyoji Tanaka; Issei Tanaka; Akira Shimatsu; Kazuwa Nakao
Characterization of Prophet of Pit-1 gene expression in normal pituitary and pituitary adenomas in humans.
The Journal of clinical endocrinology and metabolism 1999;84(4):1414-9.
1998: H Murabe; Masashi Mukoyama; Issei Tanaka; Kazuwa Nakao
[Adrenomedullin receptors].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(7):1919-24.
1998: H Michibata; Masashi Mukoyama; Issei Tanaka; Shinichi Suga; M Nakagawa; Rieko Ishibashi; Masahisa Goto; K Akaji; Y Fujiwara; Y Kiso; Kazuwa Nakao
Autocrine/paracrine role of adrenomedullin in cultured endothelial and mesangial cells.
Kidney international 1998;53(4):979-85.
1998: Shinichi Suga; Hiroaki Itoh; Yasato Komatsu; H Ishida; T Igaki; Jun K Yamashita; Kentaro Doi; Tae-Hwa Chun; T Yoshimasa; Issei Tanaka; Kazuwa Nakao
Regulation of endothelial production of C-type natriuretic peptide by interaction between endothelial cells and macrophages.
Endocrinology 1998;139(4):1920-6.
1998: Michio Suda; Kiyoji Tanaka; Akihiro Yasoda; Koshi Natsui; Yoko Sakuma; Issei Tanaka; Fumitaka Ushikubi; Shuh Narumiya; Kazuwa Nakao
Prostaglandin E2 (PGE2) autoamplifies its production through EP1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells.
Calcified tissue international 1998;62(4):327-31.
1997: Masaki Harada; Hiroaki Itoh; O Nakagawa; Yoshihiro Ogawa; Yoshihiro Miyamoto; Koichiro Kuwahara; Emiko Ogawa; T Igaki; Jun K Yamashita; Izuru Masuda; T Yoshimasa; Issei Tanaka; Yoshihiko Saito; Kazuwa Nakao
Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes.
Circulation 1997;96(10):3737-44.
1997: Toshio Matsumoto; Norimasa Sagawa; Masasuke Yoshida; Takahide Mori; Issei Tanaka; Masashi Mukoyama; M Kotani; Kazuwa Nakao
The prostaglandin E2 and F2 alpha receptor genes are expressed in human myometrium and are down-regulated during pregnancy.
Biochemical and biophysical research communications 1997;238(3):838-41.
1997: Masahisa Goto; Masashi Mukoyama; Shinichi Suga; T Matsumoto; M Nakagawa; Rieko Ishibashi; Masato Kasahara; Akira Sugawara; Issei Tanaka; Kazuwa Nakao
Growth-dependent induction of angiotensin II type 2 receptor in rat mesangial cells.
Hypertension 1997;30(3 Pt 1):358-62.
1997: Y Sasaki; T Takahashi; Issei Tanaka; K Nakamura; Y Okuno; O Nakagawa; Shuh Narumiya; Kazuwa Nakao
Expression of prostacyclin receptor in human megakaryocytes.
Blood 1997;90(3):1039-46.
1997: Y Sasaki; Issei Tanaka
[Prostanoid receptors].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 2():586-9.
1997: M Kotani; Issei Tanaka; Yoshihiro Ogawa; Takeshi Usui; N Tamura; Kazuhiro J Mori; Shuh Narumiya; T Yoshimi; Kazuwa Nakao
Structural organization of the human prostaglandin EP3 receptor subtype gene (PTGER3).
Genomics 1997;40(3):425-34.
1997: Masaki Harada; Yoshihiko Saito; O Nakagawa; Yoshihiro Miyamoto; M Ishikawa; Koichiro Kuwahara; Emiko Ogawa; M Nakayama; Shigeki Kamitani; Ichiro Hamanaka; Noboru Kajiyama; Izuru Masuda; Hiroaki Itoh; Issei Tanaka; Kazuwa Nakao
Role of cardiac nonmyocytes in cyclic mechanical stretch-induced myocyte hypertrophy.
Heart and vessels 1997;Suppl 12():198-200.
1996: T Matsumoto; Norimasa Sagawa; Masashi Mukoyama; Issei Tanaka; H Itoh; M Goto; H Itoh; M Horiuchi; V J Dzau; T Mori; Kazuwa Nakao
Type 2 angiotensin II receptor is expressed in human myometrium and uterine leiomyoma and is down-regulated during pregnancy.
The Journal of clinical endocrinology and metabolism 1996;81(12):4366-72.
1996: Kazuhiro J Mori; Issei Tanaka; M Kotani; F Miyaoka; T Sando; Shigeo Muro; Y Sasaki; O Nakagawa; Yoshihiro Ogawa; Takeshi Usui; S Ozaki; Atsushi Ichikawa; Shuh Narumiya; Kazuwa Nakao
Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester.
Journal of molecular medicine (Berlin, Germany) 1996;74(6):333-6.
1996: T Igaki; H Itoh; Shinichi Suga; N Hama; Yoshihiro Ogawa; Yasato Komatsu; Masashi Mukoyama; Akira Sugawara; T Yoshimasa; Issei Tanaka; Kazuwa Nakao
C-type natriuretic peptide in chronic renal failure and its action in humans.
Kidney international. Supplement 1996;55():S144-7.
1996: Michio Suda; K Tanaka; Koshi Natsui; Takeshi Usui; Issei Tanaka; M Fukushima; Chohei Shigeno; Junji Konishi; Shuh Narumiya; Atsushi Ichikawa; N Nakao
Prostaglandin E receptor subtypes in mouse osteoblastic cell line.
Endocrinology 1996;137(5):1698-705.
1995: O Nakagawa; Y Sasaki; Issei Tanaka; Takeshi Usui; T Sando; Shigeo Muro; Kazuhiro J Mori; H Itoh; T Yoshimasa; Shuh Narumiya
Gene expression of prostacyclin receptor in the hypertrophied heart of spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S270-2.
1995: I Kishimoto; T Yoshimasa; Hidenori Arai; Kazuhiko Takaya; Yoshihiro Miyamoto; Jun K Yamashita; Shinichi Suga; Yasato Komatsu; O Nakagawa; Issei Tanaka
Endothelin-induced activation of mitogen-activated protein kinases in glomerular mesangial cells from normotensive and stroke-prone spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S207-8.
1995: M Nakagawa; Issei Tanaka; Shinichi Suga; Yoshihiro Ogawa; N Tamura; M Goto; A Sugawara; T Yoshimasa; H Itoh; Masashi Mukoyama
Preparation of a monoclonal antibody against mouse brain natriuretic peptide (BNP) and tissue distribution of BNP in mice.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S186-7.
1995: M Goto; H Itoh; Issei Tanaka; Shinichi Suga; Yoshihiro Ogawa; I Kishimoto; M Nakagawa; A Sugawara; T Yoshimasa; Masashi Mukoyama
Altered gene expression of natriuretic peptide receptor subtypes in the kidney of stroke-prone spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology. Supplement 1995;22(1):S177-9.
1995: M Kotani; Issei Tanaka; Yoshihiro Ogawa; Takeshi Usui; Kazuhiro J Mori; Atsushi Ichikawa; Shuh Narumiya; T Yoshimi; Kazuwa Nakao
Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions.
Molecular pharmacology 1995;48(5):869-79.
1995: Yoshihiro Ogawa; Issei Tanaka; Mayumi Inoue; Y Yoshitake; N Isse; O Nakagawa; Takeshi Usui; H Itoh; T Yoshimasa; Shuh Narumiya
Structural organization and chromosomal assignment of the human prostacyclin receptor gene.
Genomics 1995;27(1):142-8.
1994: Y Sasaki; Takeshi Usui; Issei Tanaka; O Nakagawa; T Sando; T Takahashi; T Namba; Shuh Narumiya; Kazuwa Nakao
Cloning and expression of a cDNA for rat prostacyclin receptor.
Biochimica et biophysica acta 1994;1224(3):601-5.
1994: O Nakagawa; Issei Tanaka; Takeshi Usui; Masaki Harada; Y Sasaki; H Itoh; T Yoshimasa; T Namba; Shuh Narumiya; Kazuwa Nakao
Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system.
Circulation 1994;90(4):1643-7.
1994: T Sando; Takeshi Usui; Issei Tanaka; Kazuhiro J Mori; Y Sasaki; Y Fukuda; T Namba; Yukihiko Sugimoto; Atsushi Ichikawa; Shuh Narumiya
Molecular cloning and expression of rat prostaglandin E receptor EP2 subtype.
Biochemical and biophysical research communications 1994;200(3):1329-33.
1994: N Hama; H Itoh; Gotaro Shirakami; Shinichi Suga; Yasato Komatsu; T Yoshimasa; Issei Tanaka; Kazuhiro J Mori; Kazuwa Nakao
Detection of C-type natriuretic peptide in human circulation and marked increase of plasma CNP level in septic shock patients.
Biochemical and biophysical research communications 1994;198(3):1177-82.
1993: H Itoh; Shinichi Suga; Yoshihiro Ogawa; Issei Tanaka; Kazuwa Nakao
[Molecular biology and pharmacology of natriuretic peptide system].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(6):1548-56.
1990: J Fukata; Takeshi Usui; T Tsukada; Yoshikatsu Nakai; T Koh; T Ishihara; Issei Tanaka; K Uchida; T Yoshimasa; R Nakano
Effects of repetitive administration of corticotropin-releasing hormone combined with lysine vasopressin on plasma adrenocorticotropin and cortisol levels in secondary adrenocortical insufficiency.
The Journal of clinical endocrinology and metabolism 1990;71(6):1624-31.