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John Boothroyd

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TOP 3
Carolina E Caffaro; Carlos B Hirschberg; Anita A Koshy; Li Liu; Gusti M Zeiner; John C Boothroyd
A nucleotide sugar transporter involved in glycosylation of the toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites.
John C Boothroyd
Have it your way: how polymorphic, injected kinases and pseudokinases enable toxoplasma to subvert host defenses.
Kerry R Buchholz; Paul W Bowyer; John C Boothroyd
Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cyst.

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2013: Carolina E Caffaro; Carlos B Hirschberg; Anita A Koshy; Li Liu; Gusti M Zeiner; John C Boothroyd
A nucleotide sugar transporter involved in glycosylation of the toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites.
PLoS pathogens 2013;9(5):e1003331.
2013: John C Boothroyd
Have it your way: how polymorphic, injected kinases and pseudokinases enable toxoplasma to subvert host defenses.
PLoS pathogens 2013;9(4):e1003296.
2013: Kerry R Buchholz; Paul W Bowyer; John C Boothroyd
Bradyzoite pseudokinase 1 is crucial for efficient oral infectivity of the Toxoplasma gondii tissue cyst.
Eukaryotic cell 2013;12(3):399-410.
2012: Anita A Koshy; Jason H Melehani; Anjali J Shastri; David A Christian; Hans K Dietrich; Christopher A Hunter; John C Boothroyd
Toxoplasma co-opts host cells it does not invade.
PLoS pathogens 2012;8(7):e1002825.
2011: Kerry R Buchholz; Xiucui Chen; Patricia A Conrad; Blythe Durbin-Johnson; David J Ferguson; Heather M Fritz; David Rocke; John C Boothroyd
Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites.
Eukaryotic cell 2011;10(12):1637-47.
2011: Pedro Morgado; Yi-Ching Ong; John C Boothroyd; Melissa B Lodoen
Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction.
Infection and immunity 2011;79(11):4401-12.
2011: Moritz Treeck; Joshua E Elias; John L Sanders; John C Boothroyd
The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries.
Cell host & microbe 2011;10(4):410-9.
2011: Jessica S Tyler; Moritz Treeck; John C Boothroyd
Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication.
Trends in parasitology 2011;27(9):410-20.
2011: Michael L Reese; John C Boothroyd
A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
The Journal of biological chemistry 2011;286(33):29366-75.
2011: Carolina E Caffaro; John C Boothroyd
Evidence for host cells as the major contributor of lipids in the intravacuolar network of Toxoplasma-infected cells.
Eukaryotic cell 2011;10(8):1095-9.
2011: Carolyn I Hall; Jeralyn D Haraldsen; MacDonald R Phillips; Michael L Reese; Edgar Deu Sandoval; Gary E Ward; Eranthie Weerapana; John C Boothroyd; Paul W Bowyer; Matthew A Child; Benjamin F Cravatt; Victoria E Albrow; Matthew Bogyo
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(26):10568-73.
2011: Kirk D C Jensen; Yi-Ching Ong; Anjali J Shastri; Yiding Wang; Elia D Tait Wojno; Erwan Boedec; John C Boothroyd; Yueh-hsiu Chien; Lara Cornel; Kenneth Hu; Christopher A Hunter; jeroen saeij
Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.
Cell host & microbe 2011;9(6):472-83.
2011: Michael L Reese; jeroen saeij; Gusti Zeiner; John C Boothroyd; Jon P Boyle
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(23):9625-30.
2011: Younjoo Lee; Jun Yong Choi; Hong Fu; Colin Harvey; Sandeep Ravindran; William R Roush; John C Boothroyd; Chaitan Khosla
Chemistry and biology of macrolide antiparasitic agents.
Journal of medicinal chemistry 2011;54(8):2792-804.
2011: Yi-Ching Ong; Jon P Boyle; John C Boothroyd
Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.
PloS one 2011;6(10):e26369.
2011: Jessica S Tyler; John C Boothroyd
The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex.
PLoS pathogens 2011;7(2):e1001282.
2010: Lena Pernas; John C Boothroyd
Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8.
International journal for parasitology 2010;40(12):1367-71.
2010: Yi-Ching Ong; Michael L Reese; John C Boothroyd
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.
The Journal of biological chemistry 2010;285(37):28731-40.
2010: Gusti Zeiner; John C Boothroyd
Use of two novel approaches to discriminate between closely related host microRNAs that are manipulated by Toxoplasma gondii during infection.
RNA (New York, N.Y.) 2010;16(6):1268-74.
2010: Anita A Koshy; Ashley E Fouts; Melissa B Lodoen; Ozan Alkan; Helen M Blau; John C Boothroyd
Toxoplasma secreting Cre recombinase for analysis of host-parasite interactions.
Nature methods 2010;7(4):307-9.
2010: Gusti Zeiner; Kara L Norman; J Michael Thomson; Scott M Hammond; John C Boothroyd
Toxoplasma gondii infection specifically increases the levels of key host microRNAs.
PloS one 2010;5(1):e8742.
2010: Melissa B Lodoen; Christiane Gerke; John C Boothroyd
A highly sensitive FRET-based approach reveals secretion of the actin-binding protein toxofilin during Toxoplasma gondii infection.
Cellular microbiology 2010;12(1):55-66.
2009: Michael Reese; John C Boothroyd
A helical membrane-binding domain targets the Toxoplasma ROP2 family to the parasitophorous vacuole.
Traffic (Copenhagen, Denmark) 2009;10(10):1458-70.
2009: John C Boothroyd
Toxoplasma gondii: 25 years and 25 major advances for the field.
International journal for parasitology 2009;39(8):935-46.
2009: John C Boothroyd
Expansion of host range as a driving force in the evolution of Toxoplasma.
Memórias do Instituto Oswaldo Cruz 2009;104(2):179-84.
2009: Matthew Z Anderson; Jeremy Brewer; Upinder Singh; John C Boothroyd
A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii.
Eukaryotic cell 2009;8(3):398-409.
2009: Sandeep Ravindran; Melissa B Lodoen; Steven H L Verhelst; Matthew Bogyo; John C Boothroyd
4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.
PloS one 2009;4(12):e8143.
2008: Joe Dan Dunn; Sandeep Ravindran; Seon-Kyeong Kim; John C Boothroyd
The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4.
Infection and immunity 2008;76(12):5853-61.
2008: Jon P Boyle; Jeroen P J Saeij; Scott Y Harada; Jim W Ajioka; John C Boothroyd
Expression quantitative trait locus mapping of toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression.
Eukaryotic cell 2008;7(8):1403-14.
2008: jeroen saeij; Gustavo Arrizabalaga; John C Boothroyd
A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence.
Infection and immunity 2008;76(6):2402-10.
2008: Sandeep Ravindran; John C Boothroyd
Secretion of proteins into host cells by Apicomplexan parasites.
Traffic (Copenhagen, Denmark) 2008;9(5):647-56.
2008: Gusti Zeiner; Michael D Cleary; Ashley E Fouts; Christopher D Meiring; Edward Mocarski; John C Boothroyd
RNA analysis by biosynthetic tagging using 4-thiouracil and uracil phosphoribosyltransferase.
Methods in molecular biology (Clifton, N.J.) 2008;419():135-46.
2008: John C Boothroyd; Jean-François Dubremetz
Kiss and spit: the dual roles of Toxoplasma rhoptries.
Nature reviews. Microbiology 2008;6(1):79-88.
2007: Tam T Van; Seon-Kyeong Kim; Manel Camps; John C Boothroyd; Laura J Knoll
The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9.
International journal for parasitology 2007;37(8-9):877-85.
2007: Jon P Boyle; jeroen saeij; John C Boothroyd
Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice.
Experimental parasitology 2007;116(3):302-5.
2007: Seon-Kyeong Kim; Ashley E Fouts; John C Boothroyd
Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profiling.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5154-65.
2007: Ajai Vyas; Seon-Kyeong Kim; Nicholas Giacomini; John C Boothroyd; Robert M Sapolsky
Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6442-7.
2007: Seon-Kyeong Kim; Ariela O Karasov; John C Boothroyd
Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine.
Infection and immunity 2007;75(4):1626-34.
2007: Ashley E Fouts; John C Boothroyd
Infection with Toxoplasma gondii bradyzoites has a diminished impact on host transcript levels relative to tachyzoite infection.
Infection and immunity 2007;75(2):634-42.
2007: Vernon Bruce Carruthers; John C Boothroyd
Pulling together: an integrated model of Toxoplasma cell invasion.
Current opinion in microbiology 2007;10(1):83-9.
2007: jeroen saeij; Susan Coller; Jon P Boyle; Maria E Jerome; Michael W White; John C Boothroyd
Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue.
Nature 2007;445(7125):324-7.
2006: jeroen saeij; Jon P Boyle; Susan Coller; S Taylor; L David Sibley; E T Brooke-Powell; James W Ajioka; John C Boothroyd
Polymorphic secreted kinases are key virulence factors in toxoplasmosis.
Science (New York, N.Y.) 2006;314(5806):1780-3.
2006: Jon P Boyle; Badri Rajasekar; jeroen saeij; James W Ajioka; Matthew Berriman; Ian Paulsen; David S Roos; L David Sibley; Michael W White; John C Boothroyd
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10514-9.
2006: David L Alexander; Shirin Arastu-Kapur; Jean-François Dubremetz; John C Boothroyd
Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii.
Eukaryotic cell 2006;5(7):1169-73.
2006: Jon P Boyle; jeroen saeij; Michael D Cleary; John C Boothroyd
Analysis of gene expression during development: lessons from the Apicomplexa.
Microbes and infection / Institut Pasteur 2006;8(6):1623-30.
2006: Isabelle Coppens; Joe Dan Dunn; Julia D Romano; Marc Pypaert; HUI ZHANG; John C Boothroyd; Keith A Joiner
Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space.
Cell 2006;125(2):261-74.
2005: Jodi A Schwarz; Ashley E Fouts; Craig A Cummings; David J P Ferguson; John C Boothroyd
A novel rhoptry protein in Toxoplasma gondii bradyzoites and merozoites.
Molecular and biochemical parasitology 2005;144(2):159-66.
2005: Peter J Bradley; Chris Ward; Stephen J Cheng; David L Alexander; Susan Coller; Graham H Coombs; Joe Dan Dunn; David J Ferguson; Sanya J Sanderson; Jonathan Wastling; John C Boothroyd
Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii.
The Journal of biological chemistry 2005;280(40):34245-58.
2005: David L Alexander; Jeffrey Mital; Gary E Ward; Peter Bradley; John C Boothroyd
Identification of the moving junction complex of Toxoplasma gondii: a collaboration between distinct secretory organelles.
PLoS pathogens 2005;1(2):e17.
2005: Padmini Vanchinathan; Jeremy L Brewer; Omar S Harb; John C Boothroyd; Upinder Singh
Disruption of a locus encoding a nucleolar zinc finger protein decreases tachyzoite-to-bradyzoite differentiation in Toxoplasma gondii.
Infection and immunity 2005;73(10):6680-8.
2005: jeroen saeij; Jon P Boyle; John C Boothroyd
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host.
Trends in parasitology 2005;21(10):476-81.
2005: Seon-Kyeong Kim; John C Boothroyd
Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8038-48.
2005: Ariela O Karasov; John C Boothroyd; Gustavo Arrizabalaga
Identification and disruption of a rhoptry-localized homologue of sodium hydrogen exchangers in Toxoplasma gondii.
International journal for parasitology 2005;35(3):285-91.
2005: Michael D Cleary; Christopher Meiering; Eric Jan; Rebecca Guymon; John C Boothroyd
Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay.
Nature biotechnology 2005;23(2):232-7.
2005: jeroen saeij; Jon P Boyle; Michael E Grigg; Gustavo Arrizabalaga; John C Boothroyd
Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains.
Infection and immunity 2005;73(2):695-702.
2005: Asis Khan; Sonya Taylor; Chunlei Su; Aaron J Mackey; Jon Boyle; Robert Cole; Darius Glover; Keliang Tang; Ian Paulsen; Matthew Berriman; John C Boothroyd; Elmer R Pfefferkorn; J P Dubey; James W Ajioka; David S Roos; John C Wootton; L David Sibley
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii.
Nucleic acids research 2005;33(9):2980-92.
2004: Peter J Bradley; Nancy Li; John C Boothroyd
A GFP-based motif-trap reveals a novel mechanism of targeting for the Toxoplasma ROP4 protein.
Molecular and biochemical parasitology 2004;137(1):111-20.
2004: Nicolas Rachinel; Dominique Buzoni-Gatel; Chaitali Dutta; Franck J D Mennechet; Souphalone Luangsay; Laurie A Minns; Michael E Grigg; Stanislas Tomavo; John C Boothroyd; Lloyd H Kasper
The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2725-35.
2004: Gustavo Arrizabalaga; Felix Ruiz; Silvia N J Moreno; John C Boothroyd
Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation.
The Journal of cell biology 2004;165(5):653-62.
2004: Gustavo Arrizabalaga; John C Boothroyd
Role of calcium during Toxoplasma gondii invasion and egress.
International journal for parasitology 2004;34(3):361-8.
2004: Melissa A Miller; M E Grigg; Christine Kreuder; E R James; Ann C Melli; Paul R Crosbie; David A Jessup; John C Boothroyd; D Brownstein; Patricia A Conrad
An unusual genotype of Toxoplasma gondii is common in California sea otters (Enhydra lutris nereis) and is a cause of mortality.
International journal for parasitology 2004;34(3):275-84.
2003: John C Boothroyd; Ira J Blader; Michael Cleary; Upinder Singh
DNA microarrays in parasitology: strengths and limitations.
Trends in parasitology 2003;19(10):470-6.
2003: Jiang-Ti Kong; Michael E Grigg; Lyle Uyetake; Stephen Parmley; John C Boothroyd
Serotyping of Toxoplasma gondii infections in humans using synthetic peptides.
The Journal of infectious diseases 2003;187(9):1484-95.
2002: Peter J Bradley; Christine L Hsieh; John C Boothroyd
Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole.
Molecular and biochemical parasitology 2002;125(1-2):189-93.
2002: John C Boothroyd; Michael E Grigg
Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease?
Current opinion in microbiology 2002;5(4):438-42.
2002: Xiao-lin He; Michael E Grigg; John C Boothroyd; K Christopher Garcia
Structure of the immunodominant surface antigen from the Toxoplasma gondii SRS superfamily.
Nature structural biology 2002;9(8):606-11.
2002: Michael D Cleary; Upinder Singh; Ira J Blader; Jeremy L Brewer; John C Boothroyd
Toxoplasma gondii asexual development: identification of developmentally regulated genes and distinct patterns of gene expression.
Eukaryotic cell 2002;1(3):329-40.
2002: Upinder Singh; Jeremy L Brewer; John C Boothroyd
Genetic analysis of tachyzoite to bradyzoite differentiation mutants in Toxoplasma gondii reveals a hierarchy of gene induction.
Molecular microbiology 2002;44(3):721-33.
2002: Manel Camps; Gustavo Arrizabalaga; John C Boothroyd
An rRNA mutation identifies the apicoplast as the target for clindamycin in Toxoplasma gondii.
Molecular microbiology 2002;43(5):1309-18.
2002: Silvia Vaena de Avalos; Ira J Blader; Michael Fisher; John C Boothroyd; Barbara A Burleigh
Immediate/early response to Trypanosoma cruzi infection involves minimal modulation of host cell transcription.
The Journal of biological chemistry 2002;277(1):639-44.
2001: Michael E Grigg; S Bonnefoy; Adrian Hehl; Y Suzuki; John C Boothroyd
Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries.
Science (New York, N.Y.) 2001;294(5540):161-5.
2001: C Lekutis; David J Ferguson; Michael E Grigg; Manel Camps; John C Boothroyd
Surface antigens of Toxoplasma gondii: variations on a theme.
International journal for parasitology 2001;31(12):1285-92.
2001: Ian D Manger; John C Boothroyd
Targeted disruption of an essential RNA-binding protein perturbs cell division in Trypanosoma brucei.
Molecular and biochemical parasitology 2001;116(2):239-45.
2001: Peter J Bradley; John C Boothroyd
The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal.
International journal for parasitology 2001;31(11):1177-86.
2001: Michael E Grigg; J Ganatra; John C Boothroyd; T P Margolis
Unusual abundance of atypical strains associated with human ocular toxoplasmosis.
The Journal of infectious diseases 2001;184(5):633-9.
2001: Manel Camps; John C Boothroyd
Toxoplasma gondii: selective killing of extracellular parasites by oxidation using pyrrolidine dithiocarbamate.
Experimental parasitology 2001;98(4):206-14.
2001: Laura J Knoll; G L Furie; John C Boothroyd
Adaptation of signature-tagged mutagenesis for Toxoplasma gondii: a negative screening strategy to isolate genes that are essential in restrictive growth conditions.
Molecular and biochemical parasitology 2001;116(1):11-6.
2001: Ira J Blader; Ian D Manger; John C Boothroyd
Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells.
The Journal of biological chemistry 2001;276(26):24223-31.
2001: DC McFadden; Manel Camps; John C Boothroyd
Resistance as a tool in the study of old and new drug targets in Toxoplasma.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2001;4(2):79-84.
2001: Lyle Uyetake; E Ortega-Barria; John C Boothroyd
Isolation and characterization of a cold-sensitive attachment/invasion mutant of Toxoplasma gondii.
Experimental parasitology 2001;97(1):55-9.
2001: Michael E Grigg; John C Boothroyd
Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-restriction fragment length polymorphism analysis at the B1 gene.
Journal of clinical microbiology 2001;39(1):398-400.
2000: MW Black; Gustavo Arrizabalaga; John C Boothroyd
Ionophore-resistant mutants of Toxoplasma gondii reveal host cell permeabilization as an early event in egress.
Molecular and cellular biology 2000;20(24):9399-408.
2000: Adrian Hehl; C Lekutis; Michael E Grigg; Peter J Bradley; Jean-François Dubremetz; E Ortega-Barria; John C Boothroyd
Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cells.
Infection and immunity 2000;68(12):7078-86.
2000: K Wilson; Lyle Uyetake; John C Boothroyd
The trans-spliced L30 ribosomal protein mRNA of Trypanosoma brucei is not subject to autogenous feedback control at the messenger RNA level.
Molecular and biochemical parasitology 2000;111(1):199-205.
2000: C Lekutis; David J Ferguson; John C Boothroyd
Toxoplasma gondii: identification of a developmentally regulated family of genes related to SAG2.
Experimental parasitology 2000;96(2):89-96.
2000: MW Black; John C Boothroyd
Lytic cycle of Toxoplasma gondii.
Microbiology and molecular biology reviews : MMBR 2000;64(3):607-23.
2000: DC McFadden; Stanislas Tomavo; E A Berry; John C Boothroyd
Characterization of cytochrome b from Toxoplasma gondii and Q(o) domain mutations as a mechanism of atovaquone-resistance.
Molecular and biochemical parasitology 2000;108(1):1-12.
1999: DC McFadden; John C Boothroyd
Cytochrome b mutation identified in a decoquinate-resistant mutant of Toxoplasma gondii.
The Journal of eukaryotic microbiology 1999;46(5):81S-82S.
1999: Peter J Bradley; John C Boothroyd
Identification of the pro-mature processing site of Toxoplasma ROP1 by mass spectrometry.
Molecular and biochemical parasitology 1999;100(1):103-9.
1999: K Wilson; Lyle Uyetake; John C Boothroyd
Trypanosoma brucei: cis-acting sequences involved in the developmental regulation of PARP expression.
Experimental parasitology 1999;91(3):222-30.
1999: E Ortega-Barria; John C Boothroyd
A Toxoplasma lectin-like activity specific for sulfated polysaccharides is involved in host cell infection.
The Journal of biological chemistry 1999;274(3):1267-76.
1998: Laura J Knoll; John C Boothroyd
Molecular Biology's Lessons about Toxoplasma Development: Stage-specific Homologs.
Parasitology today (Personal ed.) 1998;14(12):490-3.
1998: Ian D Manger; John C Boothroyd
Identification of a nuclear protein in Trypanosoma brucei with homology to RNA-binding proteins from cis-splicing systems.
Molecular and biochemical parasitology 1998;97(1-2):1-11.
1998: D Soldati; A Lassen; J F Dubremetz; John C Boothroyd
Processing of Toxoplasma ROP1 protein in nascent rhoptries.
Molecular and biochemical parasitology 1998;96(1-2):37-48.
1998: Ian D Manger; Adrian Hehl; John C Boothroyd
The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1.
Infection and immunity 1998;66(5):2237-44.
1998: Ian D Manger; Adrian Hehl; Stephen Parmley; L David Sibley; M Marra; LaDeana W Hillier; Robert H Waterston; John C Boothroyd
Expressed sequence tag analysis of the bradyzoite stage of Toxoplasma gondii: identification of developmentally regulated genes.
Infection and immunity 1998;66(4):1632-7.
1998: MW Black; John C Boothroyd
Development of a stable episomal shuttle vector for Toxoplasma gondii.
The Journal of biological chemistry 1998;273(7):3972-9.
1998: Laura J Knoll; John C Boothroyd
Isolation of developmentally regulated genes from Toxoplasma gondii by a gene trap with the positive and negative selectable marker hypoxanthine-xanthine-guanine phosphoribosyltransferase.
Molecular and cellular biology 1998;18(2):807-14.
1998: John C Boothroyd; Adrian Hehl; Laura J Knoll; Ian D Manger
The surface of Toxoplasma: more and less.
International journal for parasitology 1998;28(1):3-9.
1998: James W Ajioka; John C Boothroyd; Brian P Brunk; Adrian Hehl; LaDeana W Hillier; Ian D Manger; M Marra; G C Overton; David S Roos; Kiew-Lian Wan; Robert H Waterston; L David Sibley
Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa.
Genome research 1998;8(1):18-28.
1998: Frank Seeber; Jean-François Dubremetz; John C Boothroyd
Analysis of Toxoplasma gondii stably transfected with a transmembrane variant of its major surface protein, SAG1.
Journal of cell science 1998;111 ( Pt 1)():23-9.
1997: Adrian Hehl; T Krieger; John C Boothroyd
Identification and characterization of SRS1, a Toxoplasma gondii surface antigen upstream of and related to SAG1.
Molecular and biochemical parasitology 1997;89(2):271-82.
1997: Adrian Hehl; Ian D Manger; John C Boothroyd
Genetic analysis in Toxoplasma: gene discovery with expressed sequence tags and rapid mapping of natural polymorphisms.
Methods (San Diego, Calif.) 1997;13(2):89-102.
1997: John C Boothroyd; M Black; S Bonnefoy; Adrian Hehl; Laura J Knoll; Ian D Manger; E Ortega-Barria; Stanislas Tomavo
Genetic and biochemical analysis of development in Toxoplasma gondii.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1997;352(1359):1347-54.
1997: DC McFadden; Frank Seeber; John C Boothroyd
Use of Toxoplasma gondii expressing beta-galactosidase for colorimetric assessment of drug activity in vitro.
Antimicrobial agents and chemotherapy 1997;41(9):1849-53.
1996: Mark Field; John C Boothroyd
Sequence divergence in a family of variant surface glycoprotein genes from trypanosomes: coding region hypervariability and downstream recombinogenic repeats.
Journal of molecular evolution 1996;42(5):500-11.
1996: Frank Seeber; John C Boothroyd
Escherichia coli beta-galactosidase as an in vitro and in vivo reporter enzyme and stable transfection marker in the intracellular protozoan parasite Toxoplasma gondii.
Gene 1996;169(1):39-45.
1996: Ruching Hsia; T Beals; John C Boothroyd
Use of chimeric recombinant polypeptides to analyse conformational, surface epitopes on trypanosome variant surface glycoproteins.
Molecular microbiology 1996;19(1):53-63.
1995: S Tomavo; John C Boothroyd
Interconnection between organellar functions, development and drug resistance in the protozoan parasite, Toxoplasma gondii.
International journal for parasitology 1995;25(11):1293-9.
1995: Mark Field; John C Boothroyd
Trypanosoma brucei: molecular cloning of homologues of small GTP-binding proteins involved in vesicle trafficking.
Experimental parasitology 1995;81(3):313-20.
1995: D Soldati; Kami Kim; J Kampmeier; J F Dubremetz; John C Boothroyd
Complementation of a Toxoplasma gondii ROP1 knock-out mutant using phleomycin selection.
Molecular and biochemical parasitology 1995;74(1):87-97.
1995: M Black; Frank Seeber; D Soldati; Kami Kim; John C Boothroyd
Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii.
Molecular and biochemical parasitology 1995;74(1):55-63.
1995: Kami Kim; John C Boothroyd
Toxoplasma gondii: stable complementation of sag1 (p30) mutants using SAG1 transfection and fluorescence-activated cell sorting.
Experimental parasitology 1995;80(1):46-53.
1995: D Soldati; John C Boothroyd
A selector of transcription initiation in the protozoan parasite Toxoplasma gondii.
Molecular and cellular biology 1995;15(1):87-93.
1995: Mark Field; Helen I Field; John C Boothroyd
A homologue of the nuclear GTPase ran/TC4 from Trypanosoma brucei.
Molecular and biochemical parasitology 1995;69(1):131-4.
1994: Kami Kim; R Bülow; J Kampmeier; John C Boothroyd
Conformationally appropriate expression of the Toxoplasma antigen SAG1 (p30) in CHO cells.
Infection and immunity 1994;62(1):203-9.
1993: Kami Kim; D Soldati; John C Boothroyd
Gene replacement in Toxoplasma gondii with chloramphenicol acetyltransferase as selectable marker.
Science (New York, N.Y.) 1993;262(5135):911-4.
1993: L David Sibley; E R Pfefferkorn; John C Boothroyd
Development of genetic systems for Toxoplasma gondii.
Parasitology today (Personal ed.) 1993;9(10):392-5.
1993: J D Bangs; L Uyetake; M J Brickman; A E Balber; John C Boothroyd
Molecular cloning and cellular localization of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals in a lower eukaryote.
Journal of cell science 1993;105 ( Pt 4)():1101-13.
1993: D Soldati; John C Boothroyd
Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii.
Science (New York, N.Y.) 1993;260(5106):349-52.
1993: John C Boothroyd
Population biology of Toxoplasma: clonality, virulence, and speciation (or not).
Infectious agents and disease 1993;2(2):100-2.
1993: John C Boothroyd; L David Sibley
Population biology of Toxoplasma gondii.
Research in immunology 1993;144(1):14-6.
1992: L David Sibley; A J LeBlanc; E R Pfefferkorn; John C Boothroyd
Generation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii.
Genetics 1992;132(4):1003-15.
1992: L David Sibley; John C Boothroyd
Virulent strains of Toxoplasma gondii comprise a single clonal lineage.
Nature 1992;359(6390):82-5.
1992: T P Beals; John C Boothroyd
Sequence divergence among members of a trypanosome variant surface glycoprotein gene family.
Journal of molecular biology 1992;225(4):973-83.
1992: T P Beals; John C Boothroyd
Genomic organization and context of a trypanosome variant surface glycoprotein gene family.
Journal of molecular biology 1992;225(4):961-71.
1992: J D Bangs; P F Crain; T Hashizume; J A McCloskey; John C Boothroyd
Mass spectrometry of mRNA cap 4 from trypanosomatids reveals two novel nucleosides.
The Journal of biological chemistry 1992;267(14):9805-15.
1992: L David Sibley; John C Boothroyd
Construction of a molecular karyotype for Toxoplasma gondii.
Molecular and biochemical parasitology 1992;51(2):291-300.
1992: P N Ossorio; J D Schwartzman; John C Boothroyd
A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual charge asymmetry.
Molecular and biochemical parasitology 1992;50(1):1-15.
1991: P N Ossorio; L David Sibley; John C Boothroyd
Mitochondrial-like DNA sequences flanked by direct and inverted repeats in the nuclear genome of Toxoplasma gondii.
Journal of molecular biology 1991;222(3):525-36.
1991: L David Sibley; E R Pfefferkorn; John C Boothroyd
Proposal for a uniform genetic nomenclature in Toxoplasma gondii.
Parasitology today (Personal ed.) 1991;7(12):327-8.
1991: R Bülow; John C Boothroyd
Protection of mice from fatal Toxoplasma gondii infection by immunization with p30 antigen in liposomes.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(10):3496-500.
1991: Patricia Dorn; R A Aman; John C Boothroyd
Inhibition of protein synthesis results in super-induction of procyclin (PARP) RNA levels.
Molecular and biochemical parasitology 1991;44(1):133-9.
1990: M R Hobbs; John C Boothroyd
An expression-site-associated gene family of trypanosomes is expressed in vivo and shows homology to a variant surface glycoprotein gene.
Molecular and biochemical parasitology 1990;43(1):1-16.
1990: C M Grover; P Thulliez; Jack S Remington; John C Boothroyd
Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid.
Journal of clinical microbiology 1990;28(10):2297-301.
1990: D Perelman; John C Boothroyd
Lack of introns in the ribosomal protein gene S14 of trypanosomes.
Molecular and cellular biology 1990;10(6):3284-8.
1989: M L Muhich; M P Hsu; John C Boothroyd
Heat-shock disruption of trans-splicing in trypanosomes: effect on Hsp70, Hsp85 and tubulin mRNA synthesis.
Gene 1989;82(1):169-75.
1989: J L Burg; C M Grover; P Pouletty; John C Boothroyd
Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction.
Journal of clinical microbiology 1989;27(8):1787-92.
1989: M P Hsu; M L Muhich; John C Boothroyd
A developmentally regulated gene of trypanosomes encodes a homologue of rat protein-disulfide isomerase and phosphoinositol-phospholipase C.
Biochemistry 1989;28(15):6440-6.
1989: M L Muhich; John C Boothroyd
Synthesis of trypanosome hsp70 mRNA is resistant to disruption of trans-splicing by heat shock.
The Journal of biological chemistry 1989;264(13):7107-10.
1989: S D Nagel; John C Boothroyd
The major surface antigen, P30, of Toxoplasma gondii is anchored by a glycolipid.
The Journal of biological chemistry 1989;264(10):5569-74.
1988: J L Burg; D Perelman; L H Kasper; P L Ware; John C Boothroyd
Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(10):3584-91.
1988: M L Muhich; John C Boothroyd
Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis.
Molecular and cellular biology 1988;8(9):3837-46.
1988: S D Nagel; John C Boothroyd
The alpha- and beta-tubulins of Toxoplasma gondii are encoded by single copy genes containing multiple introns.
Molecular and biochemical parasitology 1988;29(2-3):261-73.
1988: R E Sutton; John C Boothroyd
Trypanosome trans-splicing utilizes 2'-5' branches and a corresponding debranching activity.
The EMBO journal 1988;7(5):1431-7.
1988: R E Sutton; John C Boothroyd
The cap of both miniexon-derived RNA and mRNA of trypanosomes is 7-methylguanosine.
Molecular and cellular biology 1988;8(1):494-6.
1987: D A Campbell; K Kubo; C G Clark; John C Boothroyd
Precise identification of cleavage sites involved in the unusual processing of trypanosome ribosomal RNA.
Journal of molecular biology 1987;196(1):113-24.
1986: R E Sutton; John C Boothroyd
Evidence for trans splicing in trypanosomes.
Cell 1986;47(4):527-35.