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Dirk Bootsma

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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van der Horst Gijsbertus T J; Meira Lisiane; Gorgels Theo G M F; de Wit Jan; Velasco-Miguel Susana; Richardson James A; Kamp Yvonne; Vreeswijk Maaike P G; Smit Bep; Bootsma Dirk; Hoeijmakers Jan H J; Friedberg Errol C
UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice.
Bootsma D
The "Dutch DNA Repair Group", in retrospect.
de Boer J; van Steeg H; Berg R J; Garssen J; de Wit J; van Oostrum C T; Beems R B; van der Horst G T; van Kreijl C F; de Gruijl F R; Bootsma D; Hoeijmakers J H; Weeda G
Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.

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2002: van der Horst Gijsbertus T J; Meira Lisiane; Gorgels Theo G M F; de Wit Jan; Velasco-Miguel Susana; Richardson James A; Kamp Yvonne; Vreeswijk Maaike P G; Smit Bep; Bootsma Dirk; Hoeijmakers Jan H J; Friedberg Errol C
UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice.
DNA repair 2002;1(2):143-57.
2001: Bootsma D
The "Dutch DNA Repair Group", in retrospect.
Mutation research 2001;485(1):37-41.
1999: de Boer J; van Steeg H; Berg R J; Garssen J; de Wit J; van Oostrum C T; Beems R B; van der Horst G T; van Kreijl C F; de Gruijl F R; Bootsma D; Hoeijmakers J H; Weeda G
Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
Cancer research 1999;59(14):3489-94.
1999: van der Horst G T; Muijtjens M; Kobayashi K; Takano R; Kanno S; Takao M; de Wit J; Verkerk A; Eker A P; van Leenen D; Buijs R; Bootsma D; Hoeijmakers J H; Yasui A
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.
Nature 1999;398(6728):627-30.
1998: Sugasawa K; Ng J M; Masutani C; Iwai S; van der Spek P J; Eker A P; Hanaoka F; Bootsma D; Hoeijmakers J H
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair.
Molecular cell 1998;2(2):223-32.
1998: Weeda G; de Boer J; Donker I; de Wit J; Winkler S B; van der Horst G T; Vermeulen W; Bootsma D; Hoeijmakers J H
Molecular basis of DNA repair mechanisms and syndromes.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;154():147-55.
1997: Sugasawa K; Ng J M; Masutani C; Maekawa T; Uchida A; van der Spek P J; Eker A P; Rademakers S; Visser C; Aboussekhra A; Wood R D; Hanaoka F; Bootsma D; Hoeijmakers J H
Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity.
Molecular and cellular biology 1997;17(12):6924-31.
1997: Masutani C; Araki M; Sugasawa K; van der Spek P J; Yamada A; Uchida A; Maekawa T; Bootsma D; Hoeijmakers J H; Hanaoka F
Identification and characterization of XPC-binding domain of hHR23B.
Molecular and cellular biology 1997;17(12):6915-23.
1997: van Gool A J; Citterio E; Rademakers S; van Os R; Vermeulen W; Constantinou A; Egly J M; Bootsma D; Hoeijmakers J H
The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.
The EMBO journal 1997;16(19):5955-65.
1997: Weeda G; Donker I; de Wit J; Morreau H; Janssens R; Vissers C J; Nigg A; van Steeg H; Bootsma D; Hoeijmakers J H
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence.
Current biology : CB 1997;7(6):427-39.
1997: van der Horst G T; van Steeg H; Berg R J; van Gool A J; de Wit J; Weeda G; Morreau H; Beems R B; van Kreijl C F; de Gruijl F R; Bootsma D; Hoeijmakers J H
Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition.
Cell 1997;89(3):425-35.
1997: Essers J; Hendriks R W; Swagemakers S M; Troelstra C; de Wit J; Bootsma D; Hoeijmakers J H; Kanaar R
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
Cell 1997;89(2):195-204.
1997: Vermeulen W; de Boer J; Citterio E; van Gool A J; van der Horst G T; Jaspers N G; de Laat W L; Sijbers A M; van der Spek P J; Sugasawa K; Weeda G; Winkler G S; Bootsma D; Egly J M; Hoeijmakers J H
Mammalian nucleotide excision repair and syndromes.
Biochemical Society transactions 1997;25(1):309-15.
1996: van der Spek P J; Kobayashi K; Bootsma D; Takao M; Eker A P; Yasui A
Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors.
Genomics 1996;37(2):177-82.
1996: McKay M J; Troelstra C; van der Spek P; Kanaar R; Smit B; Hagemeijer A; Bootsma D; Hoeijmakers J H
Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse.
Genomics 1996;36(2):305-15.
1996: Sijbers A M; van der Spek P J; Odijk H; van den Berg J; van Duin M; Westerveld A; Jaspers N G; Bootsma D; Hoeijmakers J H
Mutational analysis of the human nucleotide excision repair gene ERCC1.
Nucleic acids research 1996;24(17):3370-80.
1996: Roest H P; van Klaveren J; de Wit J; van Gurp C G; Koken M H; Vermey M; van Roijen J H; Hoogerbrugge J W; Vreeburg J T; Baarends W M; Bootsma D; Grootegoed J A; Hoeijmakers J H
Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.
Cell 1996;86(5):799-810.
1996: Sugasawa K; Masutani C; Uchida A; Maekawa T; van der Spek P J; Bootsma D; Hoeijmakers J H; Hanaoka F
HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro.
Molecular and cellular biology 1996;16(9):4852-61.
1996: van der Spek P J; Eker A; Rademakers S; Visser C; Sugasawa K; Masutani C; Hanaoka F; Bootsma D; Hoeijmakers J H
XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes.
Nucleic acids research 1996;24(13):2551-9.
1996: McKay M; van der Spek P; Roest H; Bootsma D
Conference report: 10th International Congress of Radiation Research, Würzburg, Germany, August 27-September 1, 1995.
Mutation research 1996;363(2):137-46.
1996: van der Spek P J; Visser C E; Hanaoka F; Smit B; Hagemeijer A; Bootsma D; Hoeijmakers J H
Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23.
Genomics 1996;31(1):20-7.
1995: Lekanne Deprez R H; Riegman P H; Groen N A; Warringa U L; van Biezen N A; Molijn A C; Bootsma D; de Jong P J; Menon A G; Kley N A
Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma.
Oncogene 1995;10(8):1521-8.
1995: Bootsma D; Weeda G; Vermeulen W; van Vuuren H; Troelstra C; van der Spek P; Hoeijmakers J
Nucleotide excision repair syndromes: molecular basis and clinical symptoms.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;347(1319):75-81.
1994: van Gool A J; Verhage R; Swagemakers S M; van de Putte P; Brouwer J; Troelstra C; Bootsma D; Hoeijmakers J H
RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.
The EMBO journal 1994;13(22):5361-9.
1994: Lekanne Deprez R H; Bianchi A B; Groen N A; Seizinger B R; Hagemeijer A; van Drunen E; Bootsma D; Koper J W; Avezaat C J; Kley N
Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.
American journal of human genetics 1994;54(6):1022-9.
1994: Bootsma D; Hoeijmakers J H
The molecular basis of nucleotide excision repair syndromes.
Mutation research 1994;307(1):15-23.
1994: Keeney S; Eker A P; Brody T; Vermeulen W; Bootsma D; Hoeijmakers J H; Linn S
Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):4053-6.
1994: Masutani C; Sugasawa K; Yanagisawa J; Sonoyama T; Ui M; Enomoto T; Takio K; Tanaka K; van der Spek P J; Bootsma D
Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.
The EMBO journal 1994;13(8):1831-43.
1994: van Vuuren A J; Vermeulen W; Ma L; Weeda G; Appeldoorn E; Jaspers N G; van der Eb A J; Bootsma D; Hoeijmakers J H; Humbert S
Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).
The EMBO journal 1994;13(7):1645-53.
1994: Vermeulen W; Scott R J; Rodgers S; Müller H J; Cole J; Arlett C F; Kleijer W J; Bootsma D; Hoeijmakers J H; Weeda G
Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3.
American journal of human genetics 1994;54(2):191-200.
1994: LeKanne Deprez R H; Groen N A; Louz D; Hagemeijer A; van Drunen E; Koper J W; Avezaat C J; Bootsma D; van der Kwast T H; Zwarthoff E C
Constitutional DNA-level aberrations in chromosome 22 in a patient with multiple meningiomas.
Genes, chromosomes & cancer 1994;9(2):124-8.
1993: van Vuuren A J; Appeldoorn E; Odijk H; Yasui A; Jaspers N G; Bootsma D; Hoeijmakers J H
Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.
The EMBO journal 1993;12(9):3693-701.
1993: Vermeulen W; Jaeken J; Jaspers N G; Bootsma D; Hoeijmakers J H
Xeroderma pigmentosum complementation group G associated with Cockayne syndrome.
American journal of human genetics 1993;53(1):185-92.
1993: Weeda G; Hoeijmakers J H; Bootsma D
Genes controlling nucleotide excision repair in eukaryotic cells.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(4):249-58.
1993: Troelstra C; Hesen W; Bootsma D; Hoeijmakers J H
Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B.
Nucleic acids research 1993;21(3):419-26.
1993: Bootsma D
The genetic defect in DNA repair deficiency syndromes. EACR--Mühlbock Memorial Lecture, 1993.
European journal of cancer (Oxford, England : 1990) 1993;29A(10):1482-8.
1992: Troelstra C; van Gool A; de Wit J; Vermeulen W; Bootsma D; Hoeijmakers J H
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes.
Cell 1992;71(6):939-53.
1992: von Lindern M; Fornerod M; Soekarman N; van Baal S; Jaegle M; Hagemeijer A; Bootsma D; Grosveld G
Translocation t(6;9) in acute non-lymphocytic leukaemia results in the formation of a DEK-CAN fusion gene.
Baillière's clinical haematology 1992;5(4):857-79.
1992: Eker A P; Vermeulen W; Miura N; Tanaka K; Jaspers N G; Hoeijmakers J H; Bootsma D
Xeroderma pigmentosum group A correcting protein from calf thymus.
Mutation research 1992;274(3):211-24.
1992: Koken M H; Smit E M; Jaspers-Dekker I; Oostra B A; Hagemeijer A; Bootsma D; Hoeijmakers J H
Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.
Genomics 1992;12(3):447-53.
1991: Weeda G; Ma L; van Ham R C; Bootsma D; van der Eb A J; Hoeijmakers J H
Characterization of the mouse homolog of the XPBC/ERCC-3 gene implicated in xeroderma pigmentosum and Cockayne's syndrome.
Carcinogenesis 1991;12(12):2361-8.
1991: Koken M H; Reynolds P; Jaspers-Dekker I; Prakash L; Prakash S; Bootsma D; Hoeijmakers J H
Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):8865-9.
1991: Vermeulen W; Stefanini M; Giliani S; Hoeijmakers J H; Bootsma D
Xeroderma pigmentosum complementation group H falls into complementation group D.
Mutation research 1991;255(2):201-8.
1991: Koken M; Reynolds P; Bootsma D; Hoeijmakers J; Prakash S; Prakash L
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3832-6.
1991: Lekanne Deprez R H; Groen N A; van Biezen N A; Hagemeijer A; van Drunen E; Koper J W; Avezaat C J; Bootsma D; Zwarthoff E C
A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene.
American journal of human genetics 1991;48(4):783-90.
1991: Bootsma D; Hoeijmakers J H
The genetic basis of xeroderma pigmentosum.
Annales de génétique 1991;34(3-4):143-50.
1990: Troelstra C; Odijk H; de Wit J; Westerveld A; Thompson L H; Bootsma D; Hoeijmakers J H
Molecular cloning of the human DNA excision repair gene ERCC-6.
Molecular and cellular biology 1990;10(11):5806-13.
1990: Weeda G; van Ham R C; Vermeulen W; Bootsma D; van der Eb A J; Hoeijmakers J H
A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome.
Cell 1990;62(4):777-91.
1990: Weeda G; van Ham R C; Masurel R; Westerveld A; Odijk H; de Wit J; Bootsma D; van der Eb A J; Hoeijmakers J H
Molecular cloning and biological characterization of the human excision repair gene ERCC-3.
Molecular and cellular biology 1990;10(6):2570-81.
1989: Bootsma D; Keijzer W; Jung E G; Bohnert E
Xeroderma pigmentosum complementation group XP-I withdrawn.
Mutation research 1989;218(2):149-51.
1989: van Duin M; van Den Tol J; Hoeijmakers J H; Bootsma D; Rupp I P; Reynolds P; Prakash L; Prakash S
Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions.
Molecular and cellular biology 1989;9(4):1794-8.
1989: van Duin M; Vredeveldt G; Mayne L V; Odijk H; Vermeulen W; Klein B; Weeda G; Hoeijmakers J H; Bootsma D; Westerveld A
The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I.
Mutation research 1989;217(2):83-92.
1989: Keijzer W; Mulder M P; Langeveld J C; Smit E M; Bos J L; Bootsma D; Hoeijmakers J H
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
Cancer research 1989;49(5):1229-35.
1988: van Duin M; van den Tol J; Warmerdam P; Odijk H; Meijer D; Westerveld A; Bootsma D; Hoeijmakers J H
Evolution and mutagenesis of the mammalian excision repair gene ERCC-1.
Nucleic acids research 1988;16(12):5305-22.
1988: van Duin M; Janssen J H; de Wit J; Hoeijmakers J H; Thompson L H; Bootsma D; Westerveld A
Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants.
Mutation research 1988;193(2):123-30.
1987: van Duin M; Koken M H; van den Tol J; ten Dijke P; Odijk H; Westerveld A; Bootsma D; Hoeijmakers J H
Genomic characterization of the human DNA excision repair gene ERCC-1.
Nucleic acids research 1987;15(22):9195-213.
1987: Hermans A; Heisterkamp N; von Linden M; van Baal S; Meijer D; van der Plas D; Wiedemann L M; Groffen J; Bootsma D; Grosveld G
Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia.
Cell 1987;51(1):33-40.
1987: Keijzer W; Stefanini M; Bootsma D; Verkerk A; Geurts van Kessel A H; Jongkind J F; Westerveld A
Localization of a gene involved in complementation of the defect in xeroderma pigmentosum group A cells on human chromosome 1.
Experimental cell research 1987;169(2):490-501.
1987: Grosveld G; Hermans A; De Klein A; Bootsma D; Heisterkamp N; Groffen J
The role of the Philadelphia translocation in chronic myelocytic leukemia.
Annals of the New York Academy of Sciences 1987;511():262-9.
1986: Zwetsloot J C; Hoeymakers J H; Vermeulen W; Eker A P; Bootsma D
Unscheduled DNA synthesis in xeroderma pigmentosum cells after microinjection of yeast photoreactivating enzyme.
Mutation research 1986;165(2):109-15.
1986: van Duin M; de Wit J; Odijk H; Westerveld A; Yasui A; Koken M H; Hoeijmakers J H; Bootsma D
Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.
Cell 1986;44(6):913-23.
1986: De Klein A; Hermans A; Bootsma D; Grosveld G; Heisterkamp N; Stam K; Groffen J
The role of the Philadelphia translocation in chronic myelocytic leukemia.
Annals of clinical research 1986;18(5-6):278-83.
1985: Stefanini M; Keijzer W; Westerveld A; Bootsma D
Interspecies complementation analysis of xeroderma pigmentosum and UV-sensitive Chinese hamster cells.
Experimental cell research 1985;161(2):373-80.
1985: Zwetsloot J C; Vermeulen W; Hoeijmakers J H; Yasui A; Eker A P; Bootsma D
Microinjected photoreactivating enzymes from Anacystis and Saccharomyces monomerize dimers in chromatin of human cells.
Mutation research 1985;146(1):71-7.
1985: Fischer E; Keijzer W; Thielmann H W; Popanda O; Bohnert E; Edler L; Jung E G; Bootsma D
A ninth complementation group in xeroderma pigmentosum, XP I.
Mutation research 1985;145(3):217-25.
1984: Hagemeijer A; Bartram C R; Smit E M; van Agthoven A J; Bootsma D
Is the chromosomal region 9q34 always involved in variants of the Ph1 translocation?
Cancer genetics and cytogenetics 1984;13(1):1-16.
1984: Westerveld A; Hoeijmakers J H; van Duin M; de Wit J; Odijk H; Pastink A; Wood R D; Bootsma D
Molecular cloning of a human DNA repair gene.
Nature 1984;310(5976):425-9.
1983: Bartram C R; de Klein A; Hagemeijer A; van Agthoven T; Geurts van Kessel A; Bootsma D; Grosveld G; Ferguson-Smith M A; Davies T; Stone M
Translocation of c-ab1 oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia.
Nature 1983;306(5940):277-80.
1982: Keijzer W; Verkerk A; Bootsma D
Phenotypic correction of the defect in xeroderma pigmentosum cells after fusion with isolated cytoplasts.
Experimental cell research 1982;140(1):119-25.
1982: Ruddle F H; Bootsma D; Stefani M; Keijzer W; Westerveld A; Van Cong N; Weil D; Hors-Cayla M C; Gross M S; Heuertz S; Foubert C; Frézal J; Solomon E; Shows T B; Sakaguchi A Y; Naylor S L
Workshop on mapping by somatic cell hybridization.
Progress in clinical and biological research 1982;103 Pt A():145-53.

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Dirk Bootsma

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