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Toshihiro Tanaka

Research Profile

Genes & Molecular Sequences

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Physiology

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Japan

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Oligonucleotide Array Sequence Analysis

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Yukinori Okada; Atsushi Takahashi; Tatsuhiko Tsunoda; Wanqing Wen; Jer-Yuarn Wu; Kazuhiko Yamamoto; Wei Zheng; Rajkumar Dorajoo; Min Jin Go; Naoya Hosono; Naoyuki Kamatani; Norihiro Kato; Michiaki Kubo; Natsuhiko Kumasaka; Qi Lu; Shiro Maeda; Yusuke Nakamura; Hiroko Ohmiya; Toshihiro Tanaka
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Yumiko Oishi; Ichiro Manabe; Yasushi Imai; Kazuo Hara; Momoko Horikoshi; Katsuhito Fujiu; Toshihiro Tanaka; Tadanori Aizawa; Takashi Kadowaki; Ryozo Nagai
Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.
Kiminori Nakamura; Kazunori Kato; Toshihiro Tanaka; Hirofumi Hamada
Targeting vectors for cancer gene therapy.

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All Publications

2012: Yukinori Okada; Atsushi Takahashi; Tatsuhiko Tsunoda; Wanqing Wen; Jer-Yuarn Wu; Kazuhiko Yamamoto; Wei Zheng; Rajkumar Dorajoo; Min Jin Go; Naoya Hosono; Naoyuki Kamatani; Norihiro Kato; Michiaki Kubo; Natsuhiko Kumasaka; Qi Lu; Shiro Maeda; Yusuke Nakamura; Hiroko Ohmiya; Toshihiro Tanaka
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Nature genetics 2012;44(3):302-6.
2010: Yumiko Oishi; Ichiro Manabe; Yasushi Imai; Kazuo Hara; Momoko Horikoshi; Katsuhito Fujiu; Toshihiro Tanaka; Tadanori Aizawa; Takashi Kadowaki; Ryozo Nagai
Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(6):1780-8.
2009: Kiminori Nakamura; Kazunori Kato; Toshihiro Tanaka; Hirofumi Hamada
Targeting vectors for cancer gene therapy.
Frontiers in bioscience (Elite edition) 2009;1():332-40.
2009: Jianhua Huang; Makoto Inoue; Mamoru Hasegawa; Kei Tomihara; Toshihiro Tanaka; Jiahua Chen; Hirofumi Hamada
Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limb disease.
Angiogenesis 2009;12(3):243-9.
2008: Kei Tomihara; Kazunori Kato; Yukari Masuta; Kiminori Nakamura; H Uchida; Katsunori Sasaki; Toshihiro Tanaka; Jianhua Huang; Hiroyoshi Hiratsuka; Hirofumi Hamada
Gene transfer of CD40-ligand to dendritic cells stimulates interferon-gamma production to induce growth arrest and apoptosis of tumor cells.
Gene therapy 2008;15(3):203-13.
2007: Kei Tomihara; Kazunori Kato; Yukari Masuta; Kiminori Nakamura; Toshihiro Tanaka; Hiroyoshi Hiratsuka; Hirofumi Hamada
Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.
International journal of cancer. Journal international du cancer 2007;120(7):1491-8.
2006: Toshihiro Tanaka; Jianhua Huang; Sachie Hirai; Motomu Kuroki; Masahide Kuroki; Naoki Watanabe; Kei Tomihara; Kazunori Kato; Hirofumi Hamada
Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(12):3803-13.
2005: So Tsukahara; Nobuhiko Miyazawa; Hiroyuki Akagawa; Sarka Forejtova; Karel Pavelka; Toshihiro Tanaka; Satoshi Toh; Atsushi Tajima; Iwao Akiyama; Ituro Inoue
COL6A1, the candidate gene for ossification of the posterior longitudinal ligament, is associated with diffuse idiopathic skeletal hyperostosis in Japanese.
Spine 2005;30(20):2321-4.
2005: Jianhua Huang; Kiminori Nakamura; Yoshinori Ito; Takeshi Uzuka; Masayuki Morikawa; Sachie Hirai; Kei Tomihara; Toshihiro Tanaka; Yukari Masuta; Keiji Ishii; Kazunori Kato; Hirofumi Hamada
Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rats.
Circulation 2005;112(1):76-83.
2005: Shigeru Ohtsubo; Aritoshi Iida; Kosaku Nitta; Toshihiro Tanaka; Ryo Yamada; Yozo Ohnishi; Shiro Maeda; Tatsuhiko Tsunoda; Takashi Takei; Wataru Obara; Fumihiro Akiyama; Kyoko Ito; Kazuho Honda; Keiko Uchida; Ken Tsuchiya; Wako Yumura; Takashi Ujiie; Yuriko Nagane; Satoru Miyano; Yasushi Suzuki; Ichiei Narita; Fumitake Gejyo; Tomoaki Fujioka; Hiroshi Nihei; Yusuke Nakamura
Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Journal of human genetics 2005;50(1):30-5.
2004: Hiroaki Uchida; Toshihiro Tanaka; Katsunori Sasaki; Kazunori Kato; Hironari Dehari; Yoshinori Ito; Masayoshi Kobune; Makoto Miyagishi; Kazunari Taira; Hideaki Tahara; Hirofumi Hamada
Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(1):162-71.
2003: Yasushi Sasaki; Hiroaki Mita; Minoru Toyota; Setsuko Ishida; Ichiro Morimoto; Toshiharu Yamashita; Toshihiro Tanaka; Kohzoh Imai; Yusuke Nakamura; Takashi Tokino
Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Cancer research 2003;63(23):8145-52.
2003: Toshihiro Tanaka; Katsunori Ikari; Kozo Furushima; Akihiro Okada; Hiroshi Tanaka; Ken-Ichi Furukawa; Kenichi Yoshida; Toshiyuki Ikeda; Shiro Ikegawa; Steven C Hunt; Jun Takeda; Satoshi Toh; Seiko Harata; Toshiaki Nakajima; Ituro Inoue
Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine.
American journal of human genetics 2003;73(4):812-22.
2003: Goichi Watanabe; Hidefumi Nishimori; Hideto Irifune; Yasushi Sasaki; Setsuko Ishida; Hitoshi Zembutsu; Toshihiro Tanaka; Satoshi Kawaguchi; Takuro Wada; Jun-ichi Hata; Moriaki Kusakabe; Koichi Yoshida; Yusuke Nakamura; Takashi Tokino
Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Genes, chromosomes & cancer 2003;36(3):224-32.
2003: Shuichi Tsukada; Masaru Iwai; Jun Nishiu; Makoto Itoh; Hitonobu Tomoike; Masatsugu Horiuchi; Yusuke Nakamura; Toshihiro Tanaka
Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Circulation 2003;107(2):313-9.
2003: Wataru Obara; Aritoshi Iida; Yasushi Suzuki; Toshihiro Tanaka; Fumihiro Akiyama; Shiro Maeda; Yozo Ohnishi; Ryo Yamada; Tatsuhiko Tsunoda; Takashi Takei; Kyoko Ito; Kazuho Honda; Keiko Uchida; Ken Tsuchiya; Wako Yumura; Takashi Ujiie; Yuriko Nagane; Kosaku Nitta; Satoru Miyano; Ichiei Narita; Fumitake Gejyo; Hiroshi Nihei; Tomoaki Fujioka; Yusuke Nakamura
Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Journal of human genetics 2003;48(6):293-9.
2002: Hidefumi Nishimori; Yasushi Sasaki; Koichi Yoshida; Hideto Irifune; Hitoshi Zembutsu; Toshihiro Tanaka; Tomoki Aoyama; Taisuke Hosaka; Satoshi Kawaguchi; Takuro Wada; Jun-Ichi Hata; Junya Toguchida; Yusuke Nakamura; Takashi Tokino
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Oncogene 2002;21(54):8302-9.
2002: Hideyuki Ishiguro; Takashi Shimokawa; Tatsuhiko Tsunoda; Toshihiro Tanaka; Yoshitaka Fujii; Yusuke Nakamura; Yoichi Furukawa
Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
Oncogene 2002;21(41):6387-94.
2002: Koichi Inoue; Koichi Matsuda; Makoto Itoh; Hiroshi Kawaguchi; Hitonobu Tomoike; Teruhiko Aoyagi; Ryozo Nagai; Masatsugu Hori; Yusuke Nakamura; Toshihiro Tanaka
Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Human molecular genetics 2002;11(15):1775-84.
2002: Takashi Takei; Aritoshi Iida; Kosaku Nitta; Toshihiro Tanaka; Yozo Ohnishi; Ryo Yamada; Shiro Maeda; Tatsuhiko Tsunoda; Sachiyo Takeoka; Kyoko Ito; Kazuho Honda; Keiko Uchida; Ken Tsuchiya; Yasushi Suzuki; Tomoaki Fujioka; Takashi Ujiie; Yuriko Nagane; Satoru Miyano; Ichiei Narita; Fumitake Gejyo; Hiroshi Nihei; Yusuke Nakamura
Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
American journal of human genetics 2002;70(3):781-6.
2002: Yasushi Sasaki; Setsuko Ishida; Ichiro Morimoto; Toshiharu Yamashita; Takashi Kojima; Chikashi Kihara; Toshihiro Tanaka; Kohzoh Imai; Yusuke Nakamura; Takashi Tokino
The p53 family member genes are involved in the Notch signal pathway.
The Journal of biological chemistry 2002;277(1):719-24.
2002: Kazuki Shimo-Onoda; Toshihiro Tanaka; Kozo Furushima; Toshiaki Nakajima; Satoshi Toh; Seiko Harata; Kazunori Yone; Setsuro Komiya; Hiroki Adachi; Eiji Nakamura; Hitoshi Fujimiya; Ituro Inoue
Akaike's information criterion for a measure of linkage disequilibrium.
Journal of human genetics 2002;47(12):649-55.
2002: Hisanori Haga; Ryo Yamada; Yozo Ohnishi; Yusuke Nakamura; Toshihiro Tanaka
Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.
Journal of human genetics 2002;47(11):605-10.
2002: Fumihiro Akiyama; Toshihiro Tanaka; Ryo Yamada; Yozo Ohnishi; Tatsuhiko Tsunoda; Shiro Maeda; Takashi Takei; Wataru Obara; Kyoko Ito; Kazuho Honda; Keiko Uchida; Ken Tsuchiya; Kosaku Nitta; Wako Yumura; Hiroshi Nihei; Takashi Ujiie; Yuriko Nagane; Satoru Miyano; Yasushi Suzuki; Tomoaki Fujioka; Ichiei Narita; Fumitake Gejyo; Yusuke Nakamura
Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Journal of human genetics 2002;47(10):532-8.
2002: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels.
Journal of human genetics 2002;47(4):208-12.
2001: Manabu Fujita; Yoichi Furukawa; Tatsuhiko Tsunoda; Toshihiro Tanaka; Michio Ogawa; Yusuke Nakamura
Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas.
Cancer research 2001;61(21):7722-6.
2001: C Kihara; Tatsuhiko Tsunoda; Toshihiro Tanaka; H Yamana; Yoichi Furukawa; K Ono; Osamu Kitahara; Hitoshi Zembutsu; Rempei Yanagawa; Koichi Hirata; T Takagi; Yusuke Nakamura
Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles.
Cancer research 2001;61(17):6474-9.
2001: Yu-Min Lin; K Ono; Seiji Satoh; Hideyuki Ishiguro; Manabu Fujita; Nobutomo Miwa; Toshihiro Tanaka; Tatsuhiko Tsunoda; K C Yang; Yusuke Nakamura; Yoichi Furukawa
Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis.
Cancer research 2001;61(17):6345-9.
2001: Hideyuki Ishiguro; Tatsuhiko Tsunoda; Toshihiro Tanaka; Yoshitaka Fujii; Yusuke Nakamura; Yoichi Furukawa
Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney.
Oncogene 2001;20(36):5062-6.
2001: M Matsushima-Nishiu; Motoko Unoki; K Ono; Tatsuhiko Tsunoda; Takeo Minaguchi; H Kuramoto; M Nishida; T Satoh; Toshihiro Tanaka; Yusuke Nakamura
Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN.
Cancer research 2001;61(9):3741-9.
2001: Osamu Kitahara; Yoichi Furukawa; Toshihiro Tanaka; C Kihara; K Ono; Rempei Yanagawa; Marcelo Eidi Nita; T Takagi; Yusuke Nakamura; Tatsuhiko Tsunoda
Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia.
Cancer research 2001;61(9):3544-9.
2001: Ryo Yamada; Toshihiro Tanaka; M Unoki; T Nagai; Tetsuji Sawada; Yozo Ohnishi; Tatsuhiko Tsunoda; Masao Yukioka; A Maeda; K Suzuki; H Tateishi; Takahiro Ochi; Yusuke Nakamura; Kazuhiko Yamamoto
Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease.
American journal of human genetics 2001;68(3):674-85.
2001: Aritoshi Iida; Yozo Ohnishi; K Ozaki; Y Ariji; Yusuke Nakamura; Toshihiro Tanaka
High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2.
Journal of human genetics 2001;46(10):604-8.
2001: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Genetic variations in five genes involved in the excitement of cardiomyocytes.
Journal of human genetics 2001;46(9):549-52.
2001: Tadafumi Kato; Seiji Satoh; Hiroshi Okabe; Osamu Kitahara; K Ono; C Kihara; Toshihiro Tanaka; Tatsuhiko Tsunoda; Yoshio Yamaoka; Yusuke Nakamura; Yoichi Furukawa
Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis.
Neoplasia (New York, N.Y.) 2001;3(1):4-9.
2001: Hiroyasu Iwasa; Masahiko Kurabayashi; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome.
Journal of human genetics 2001;46(3):158-62.
2001: T Itoh; K Kikuchi; Y Odagawa; S Takata; K Yano; S Okada; N Haneda; Seishi Ogawa; O Nakano; Y Kawahara; H Kasai; T Nakayama; T Fukutomi; Harumizu Sakurada; A Shimizu; Yoshio Yazaki; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome.
Journal of human genetics 2001;46(1):38-40.
2000: K Ono; Toshihiro Tanaka; Tatsuhiko Tsunoda; Osamu Kitahara; C Kihara; Atsutake Okamoto; K Ochiai; T Takagi; Yusuke Nakamura
Identification by cDNA microarray of genes involved in ovarian carcinogenesis.
Cancer research 2000;60(18):5007-11.
2000: Ryo Yamada; Toshihiro Tanaka; Yozo Ohnishi; K Suematsu; M Minami; T Seki; Masao Yukioka; A Maeda; N Murata; O Saiki; R Teshima; O Kudo; K Ishikawa; A Ueyosi; H Tateishi; M Inaba; H Goto; Y Nishizawa; Shigeto Tohma; Takahiro Ochi; Kazuhiko Yamamoto; Yusuke Nakamura
Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population.
Human genetics 2000;106(3):293-7.
2000: Yozo Ohnishi; Toshihiro Tanaka; Ryo Yamada; K Suematsu; M Minami; K Fujii; N Hoki; K Kodama; S Nagata; T Hayashi; N Kinoshita; H Sato; H Sato; T Kuzuya; H Takeda; M Hori; Yusuke Nakamura
Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population.
Human genetics 2000;106(3):288-92.
2000: Hiroo Ueno; E Kondo; Ritsuko Yamamoto-Honda; Kazuyuki Tobe; Tetsuya Nakamoto; Kazuki Sasaki; Kinuko Mitani; A Furusaka; Toshihiro Tanaka; Y Tsujimoto; Takashi Kadowaki; Hisamura Hirai
Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function.
Molecular biology of the cell 2000;11(2):735-46.
2000: T Seki; Toshihiro Tanaka; Yusuke Nakamura
Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene.
Journal of human genetics 2000;45(5):299-302.
2000: Hiroyasu Iwasa; T Itoh; Ryozo Nagai; Yusuke Nakamura; Toshihiro Tanaka
Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population.
Journal of human genetics 2000;45(3):182-3.
1999: Masayuki Matsumura; Yasushi Shiratori; Y Niwa; Toshihiro Tanaka; K Ogura; Taeko Okudaira; Masatoshi Imamura; K Okano; Shuichiro Shiina; Masao Omata
Presence of alpha-fetoprotein mRNA in blood correlates with outcome in patients with hepatocellular carcinoma.
Journal of hepatology 1999;31(2):332-9.
1999: Fumio Yoshikawa; Tsuyoshi Uchiyama; Hiroko Iwasaki; C Tomomori-Satoh; Toshihiro Tanaka; Teiichi Furuichi; Katsuhiko Mikoshiba
High efficient expression of the functional ligand binding site of the inositol 1,4,5-triphosphate receptor in Escherichia coli.
Biochemical and biophysical research communications 1999;257(3):792-7.
1998: Jun Nishiu; Toshihiro Tanaka; Yusuke Nakamura
Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3.
Genomics 1998;52(3):378-81.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; K Kikuchi; Seishi Ogawa; S Okada; S Yamagata; K Yano; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome.
Human genetics 1998;103(3):290-4.
1998: Tokiharu Takahashi; K Yamada; Toshihiro Tanaka; Keiki Kumano; Mineo Kurokawa; Naoto Hirano; Hiroaki Honda; Shigeru Chiba; Kunikazu Tsuji; Yoshio Yazaki; Tatsutoshi Nakahata; Hisamura Hirai
A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector.
Blood 1998;91(12):4509-15.
1998: Yasushi Shiratori; Fumihiko Kanai; Yohko Hikiba; H Moriyama; Hirofumi Hamada; Masayuki Matsumura; Toshihiro Tanaka; KH Lan; M Ohashi; K Okano; M Naito; Masao Omata
Gene therapy for hepatic micrometastasis of murine colon carcinoma.
Journal of hepatology 1998;28(5):886-95.
1998: Fumihiko Kanai; Takayuki Kawakami; Hirofumi Hamada; A Sadata; Y Yoshida; Toshihiro Tanaka; M Ohashi; Keisuke Tateishi; Yasushi Shiratori; Masao Omata
Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil.
Cancer research 1998;58(9):1946-51.
1998: M Ohashi; Fumihiko Kanai; Toshihiro Tanaka; KH Lan; Yasushi Shiratori; Y Komatsu; Takao Kawabe; Hideo Yoshida; Hirofumi Hamada; Masao Omata
In vivo adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing pancreatic cancer.
Japanese journal of cancer research : Gann 1998;89(4):457-62.
1998: T Itoh; Toshihiro Tanaka; Ryozo Nagai; T Kamiya; T Sawayama; T Nakayama; Hitonobu Tomoike; Harumizu Sakurada; Yoshio Yazaki; Yusuke Nakamura
Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome.
Human genetics 1998;102(4):435-9.
1998: Jun Nishiu; Toshihiro Tanaka; Yusuke Nakamura
Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method.
Genomics 1998;48(2):254-7.
1998: Keiichi Tanaka; Toshihiro Tanaka; Mineo Kurokawa; Yoichi Imai; Seishi Ogawa; Kinuko Mitani; Yoshio Yazaki; Hisamura Hirai
The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.
Blood 1998;91(5):1688-99.
1998: Toshihiro Tanaka
[Mutational analyses of familial long QT syndrome].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(2):532-9.
1998: Y Yamane-Tanaka; K Kogawa; Toshihiro Tanaka; Yusuke Nakamura; Mariko Isomura
Heterozygosities and allelic frequencies of 358 dinucleotide-repeat marker loci in the Japanese population.
Journal of human genetics 1998;43(3):165-8.
1998: Makoto Itoh; S Tsukada; T Orita; Jun Nishiu; Hitonobu Tomoike; Yusuke Nakamura; Toshihiro Tanaka
Identification by differential display of eight known genes induced during in vivo intimal hyperplasia.
Journal of human genetics 1998;43(1):9-13.
1997: KH Lan; Fumihiko Kanai; Yasushi Shiratori; M Ohashi; Toshihiro Tanaka; Taeko Okudaira; Y Yoshida; Hirofumi Hamada; Masao Omata
In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma.
Cancer research 1997;57(19):4279-84.
1997: Yoshinobu Kanda; Kinuko Mitani; Toshihiro Tanaka; Keiichi Tanaka; Seishi Ogawa; Yoshio Yazaki; Hisamura Hirai
Subcellular localization of the MEN, MLL/MEN and truncated MLL proteins expressed in leukemic cells carrying the t(11;19)(q23;p13.1) translocation.
International journal of hematology 1997;66(2):189-95.
1997: Toshihiro Tanaka; Keiichi Tanaka; Seishi Ogawa; Mineo Kurokawa; Kinuko Mitani; Yoshio Yazaki; Y Shibata; Hisamura Hirai
An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms.
Leukemia 1997;11 Suppl 3():299-302.
1997: Toshihiro Tanaka; Fumihiko Kanai; KH Lan; M Ohashi; Yasushi Shiratori; Y Yoshida; Hirofumi Hamada; Masao Omata
Adenovirus-mediated gene therapy of gastric carcinoma using cancer-specific gene expression in vivo.
Biochemical and biophysical research communications 1997;231(3):775-9.
1997: Toshihiro Tanaka; Ryozo Nagai; Hitonobu Tomoike; S Takata; K Yano; K Yabuta; N Haneda; O Nakano; A Shibata; T Sawayama; H Kasai; Yoshio Yazaki; Yusuke Nakamura
Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome.
Circulation 1997;95(3):565-7.
1997: Fumihiko Kanai; KH Lan; Yasushi Shiratori; Toshihiro Tanaka; M Ohashi; Taeko Okudaira; Y Yoshida; H Wakimoto; Hirofumi Hamada; Hideo Nakabayashi; Tatsuya Tamaoki; Masao Omata
In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene.
Cancer research 1997;57(3):461-5.