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Alisdair Boraston
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22
Kilburn, Douglas
15
Warren, Antony
10
Abbott, Wade
10
Ficko-Blean, Elizabeth
9
Gilbert, Harry
8
Davies, Gideon
7
van Bueren, Alicia Lammerts
7
McLean, Bradley
6
Bolam, David
5
Notenboom, Valerie
5
Haynes, Charles
5
Rose, David
4
Adams, Jarrett
3
Burke, Robert
3
Chiu, Patrick
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All Publications
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2009: Abbott D Wade; Ficko-Blean Elizabeth; van Bueren Alicia Lammerts; Rogowski Artur; Cartmell Alan; Coutinho Pedro M; Henrissat Bernard; Gilbert Harry J; Boraston Alisdair B
Analysis of the structural and functional diversity of plant cell wall specific family 6 carbohydrate binding modules.
Biochemistry 2009;48(43):10395-404.
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2009: Pluvinage Benjamin; Ghinet Mariana G; Brzezinski Ryszard; Boraston Alisdair B; Stubbs Keith A
Inhibition of the exo-beta-D-glucosaminidase CsxA by a glucosamine-configured castanospermine and an amino-australine analogue.
Organic & biomolecular chemistry 2009;7(20):4169-72.
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2009: Higgins Melanie A; Whitworth Garrett E; El Warry Nahida; Randriantsoa Mialy; Samain Eric; Burke Robert D; Vocadlo David J; Boraston Alisdair B
Differential recognition and hydrolysis of host carbohydrate antigens by Streptococcus pneumoniae family 98 glycoside hydrolases.
The Journal of biological chemistry 2009;284(38):26161-73.
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2009: Ficko-Blean Elizabeth; Boraston Alisdair B
N-acetylglucosamine recognition by a family 32 carbohydrate-binding module from Clostridium perfringens NagH.
Journal of molecular biology 2009;390(2):208-20.
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2009: Higgins Melanie A; Abbott D Wade; Boulanger Martin J; Boraston Alisdair B
Blood group antigen recognition by a solute-binding protein from a serotype 3 strain of Streptococcus pneumoniae.
Journal of molecular biology 2009;388(2):299-309.
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2009: Ficko-Blean Elizabeth; Gregg Katie J; Adams Jarrett J; Hehemann Jan-Hendrik; Czjzek Mirjam; Smith Steven P; Boraston Alisdair B
Portrait of an enzyme, a complete structural analysis of a multimodular {beta}-N-acetylglucosaminidase from Clostridium perfringens.
The Journal of biological chemistry 2009;284(15):9876-84.
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2009: Abbott D Wade; Macauley Matthew S; Vocadlo David J; Boraston Alisdair B
Streptococcus pneumoniae endohexosaminidase D, structural and mechanistic insight into substrate-assisted catalysis in family 85 glycoside hydrolases.
The Journal of biological chemistry 2009;284(17):11676-89.
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2009: Montanier Cedric; van Bueren Alicia Lammerts; Dumon Claire; Flint James E; Correia Marcia A; Prates Jose A; Firbank Susan J; Lewis Richard J; Grondin Gilles G; Ghinet Mariana G; Gloster Tracey M; Herve Cecile; Knox J Paul; Talbot Brian G; Turkenburg Johan P; Kerovuo Janne; Brzezinski Ryszard; Fontes Carlos M G A; Davies Gideon J; Boraston Alisdair B; Gilbert Harry J
Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3065-70.
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2009: Gregg Katie J; Boraston Alisdair B
Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of a family 101 glycoside hydrolase from Streptococcus pneumoniae.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 2):133-5.
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2009: van Bueren Alicia Lammerts; Ghinet Mariana G; Gregg Katie; Fleury Alain; Brzezinski Ryszard; Boraston Alisdair B
The structural basis of substrate recognition in an exo-beta-D-glucosaminidase involved in chitosan hydrolysis.
Journal of molecular biology 2009;385(1):131-9.
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2008: Adams Jarrett J; Gregg Katie; Bayer Edward A; Boraston Alisdair B; Smith Steven P
Structural basis of Clostridium perfringens toxin complex formation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12194-9.
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2008: Abbott D Wade; Boraston Alisdair B
Structural biology of pectin degradation by Enterobacteriaceae.
Microbiology and molecular biology reviews : MMBR 2008;72(2):301-16, table of contents.
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2008: Ficko-Blean Elizabeth; Stubbs Keith A; Nemirovsky Oksana; Vocadlo David J; Boraston Alisdair B
Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6560-5.
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2008: Gregg Katie J; Finn Ron; Abbott D Wade; Boraston Alisdair B
Divergent modes of glycan recognition by a new family of carbohydrate-binding modules.
The Journal of biological chemistry 2008;283(18):12604-13.
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2008: Abbott D Wade; Eirín-López José María; Boraston Alisdair B
Insight into ligand diversity and novel biological roles for family 32 carbohydrate-binding modules.
Molecular biology and evolution 2008;25(1):155-67.
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2008: Chitayat Seth; Gregg Katie; Adams Jarrett J; Ficko-Blean Elizabeth; Bayer Edward A; Boraston Alisdair B; Smith Steven P
Three-dimensional structure of a putative non-cellulosomal cohesin module from a Clostridium perfringens family 84 glycoside hydrolase.
Journal of molecular biology 2008;375(1):20-8.
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2007: Abbott D Wade; Boraston Alisdair B
A family 2 pectate lyase displays a rare fold and transition metal-assisted beta-elimination.
The Journal of biological chemistry 2007;282(48):35328-36.
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2007: Boraston Alisdair B; Ficko-Blean Elizabeth; Healey Michael
Carbohydrate recognition by a large sialidase toxin from Clostridium perfringens.
Biochemistry 2007;46(40):11352-60.
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2007: Chitayat Seth; Ficko-Blean Elizabeth; Adams Jarrett J; Gregg Katie; Boraston Alisdair B; Smith Steven P
NMR assignment of backbone and side chain resonances for a putative protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens.
Biomolecular NMR assignments 2007;1(1):7-9.
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2007: Abbott D Wade; Boraston Alisdair B
Specific recognition of saturated and 4,5-unsaturated hexuronate sugars by a periplasmic binding protein involved in pectin catabolism.
Journal of molecular biology 2007;369(3):759-70.
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2007: Abbott D Wade; Boraston Alisdair B
The structural basis for exopolygalacturonase activity in a family 28 glycoside hydrolase.
Journal of molecular biology 2007;368(5):1215-22.
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2007: Abbott D Wade; Hrynuik Susanne; Boraston Alisdair B
Identification and characterization of a novel periplasmic polygalacturonic acid binding protein from Yersinia enterolitica.
Journal of molecular biology 2007;367(4):1023-33.
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2007: van Bueren Alicia Lammerts; Higgins Melanie; Wang Diana; Burke Robert D; Boraston Alisdair B
Identification and structural basis of binding to host lung glycogen by streptococcal virulence factors.
Nature structural & molecular biology 2007;14(1):76-84.
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2007: van Bueren Alicia Lammerts; Boraston Alisdair B
The structural basis of alpha-glucan recognition by a family 41 carbohydrate-binding module from Thermotoga maritima.
Journal of molecular biology 2007;365(3):555-60.
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2006: Ficko-Blean Elizabeth; Boraston Alisdair B
The interaction of a carbohydrate-binding module from a Clostridium perfringens N-acetyl-beta-hexosaminidase with its carbohydrate receptor.
The Journal of biological chemistry 2006;281(49):37748-57.
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2006: Boraston Alisdair B; Wang Diana; Burke Robert D
Blood group antigen recognition by a Streptococcus pneumoniae virulence factor.
The Journal of biological chemistry 2006;281(46):35263-71.
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2006: Blake Anthony W; McCartney Lesley; Flint James E; Bolam David N; Boraston Alisdair B; Gilbert Harry J; Knox J Paul
Understanding the biological rationale for the diversity of cellulose-directed carbohydrate-binding modules in prokaryotic enzymes.
The Journal of biological chemistry 2006;281(39):29321-9.
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2006: Henshaw Joanna; Horne-Bitschy Ami; van Bueren Alicia Lammerts; Money Victoria A; Bolam David N; Czjzek Mirjam; Ekborg Nathan A; Weiner Ronald M; Hutcheson Steven W; Davies Gideon J; Boraston Alisdair B; Gilbert Harry J
Family 6 carbohydrate binding modules in beta-agarases display exquisite selectivity for the non-reducing termini of agarose chains.
The Journal of biological chemistry 2006;281(25):17099-107.
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2006: McCartney Lesley; Blake Anthony W; Flint James; Bolam David N; Boraston Alisdair B; Gilbert Harry J; Knox J Paul
Differential recognition of plant cell walls by microbial xylan-specific carbohydrate-binding modules.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(12):4765-70.
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2006: Boraston Alisdair B; Healey Michael; Klassen Jonathan; Ficko-Blean Elizabeth; Lammerts van Bueren Alicia; Law Vivian
A structural and functional analysis of alpha-glucan recognition by family 25 and 26 carbohydrate-binding modules reveals a conserved mode of starch recognition.
The Journal of biological chemistry 2006;281(1):587-98.
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2005: Kwan Emily M; Boraston Alisdair B; McLean Bradley W; Kilburn Douglas G; Warren R Antony J
N-Glycosidase-carbohydrate-binding module fusion proteins as immobilized enzymes for protein deglycosylation.
Protein engineering, design & selection : PEDS 2005;18(10):497-501.
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2005: Ficko-Blean Elizabeth; Boraston Alisdair B
Cloning, recombinant production, crystallization and preliminary X-ray diffraction studies of a family 84 glycoside hydrolase from Clostridium perfringens.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 9):834-6.
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2005: van Bueren Alicia Lammerts; Morland Carl; Gilbert Harry J; Boraston Alisdair B
Family 6 carbohydrate binding modules recognize the non-reducing end of beta-1,3-linked glucans by presenting a unique ligand binding surface.
The Journal of biological chemistry 2005;280(1):530-7.
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2005: Boraston Alisdair B
The interaction of carbohydrate-binding modules with insoluble non-crystalline cellulose is enthalpically driven.
The Biochemical journal 2005;385(Pt 2):479-84.
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2004: Lammerts van Bueren Alicia; Finn Ron; Ausió Juan; Boraston Alisdair B
Alpha-glucan recognition by a new family of carbohydrate-binding modules found primarily in bacterial pathogens.
Biochemistry 2004;43(49):15633-42.
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2004: Boraston Alisdair B; Bolam David N; Gilbert Harry J; Davies Gideon J
Carbohydrate-binding modules: fine-tuning polysaccharide recognition.
The Biochemical journal 2004;382(Pt 3):769-81.
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2004: Jamal-Talabani Sheelan; Boraston Alisdair B; Turkenburg Johan P; Tarbouriech Nicolas; Ducros Valérie M-A; Davies Gideon J
Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules.
Structure (London, England : 1993) 2004;12(7):1177-87.
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2004: Lammerts van Bueren Alicia; Boraston Alisdair B
Binding sub-site dissection of a carbohydrate-binding module reveals the contribution of entropy to oligosaccharide recognition at "non-primary" binding subsites.
Journal of molecular biology 2004;340(4):869-79.
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2004: Jamal Sheelan; Nurizzo Didier; Boraston Alisdair B; Davies Gideon J
X-ray crystal structure of a non-crystalline cellulose-specific carbohydrate-binding module: CBM28.
Journal of molecular biology 2004;339(2):253-8.
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2004: McCartney Lesley; Gilbert Harry J; Bolam David N; Boraston Alisdair B; Knox J Paul
Glycoside hydrolase carbohydrate-binding modules as molecular probes for the analysis of plant cell wall polymers.
Analytical biochemistry 2004;326(1):49-54.
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2003: Zechel David L; Boraston Alisdair B; Gloster Tracey; Boraston Catherine M; Macdonald James M; Tilbrook D Matthew G; Stick Robert V; Davies Gideon J
Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases.
Journal of the American Chemical Society 2003;125(47):14313-23.
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2003: Boraston Alisdair B; Revett Timothy J; Boraston Catherine M; Nurizzo Didier; Davies Gideon J
Structural and thermodynamic dissection of specific mannan recognition by a carbohydrate binding module, TmCBM27.
Structure (London, England : 1993) 2003;11(6):665-75.
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2003: Boraston Alisdair B; Notenboom Valerie; Warren R Antony J; Kilburn Douglas G; Rose David R; Davies Gideon
Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains.
Journal of molecular biology 2003;327(3):659-69.
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2003: Boraston Alisdair B; Kwan Emily; Chiu Patrick; Warren R Antony J; Kilburn Douglas G
Recognition and hydrolysis of noncrystalline cellulose.
The Journal of biological chemistry 2003;278(8):6120-7.
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2003: Boraston Alisdair B; Sandercock Linda E; Warren R Anthony J; Kilburn Douglas G
O-glycosylation of a recombinant carbohydrate-binding module mutant secreted by Pichia pastoris.
Journal of molecular microbiology and biotechnology 2003;5(1):29-36.
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2002: McLean Bradley W; Boraston Alisdair B; Brouwer Darren; Sanaie Nooshafarin; Fyfe Colin A; Warren R Antony J; Kilburn Douglas G; Haynes Charles A
Carbohydrate-binding modules recognize fine substructures of cellulose.
The Journal of biological chemistry 2002;277(52):50245-54.
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2002: Kwan Emily; Guarna M Marta; Boraston Alisdair B; Gilkes Neil R; Haynes Charles A; Kilburn Douglas G; Warren R Antony J
Self-activating factor X derivative fused to the C-terminus of a cellulose-binding module: Production and properties.
Biotechnology and bioengineering 2002;79(7):724-32.
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2002: Boraston Alisdair B; Nurizzo Didier; Notenboom Valerie; Ducros Valérie; Rose David R; Kilburn Douglas G; Davies Gideon J
Differential oligosaccharide recognition by evolutionarily-related beta-1,4 and beta-1,3 glucan-binding modules.
Journal of molecular biology 2002;319(5):1143-56.
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2002: Schärpf Manuela; Connelly Gregory P; Lee Gregory M; Boraston Alisdair B; Warren R Antony J; McIntosh Lawrence P
Site-specific characterization of the association of xylooligosaccharides with the CBM13 lectin-like xylan binding domain from Streptomyces lividans xylanase 10A by NMR spectroscopy.
Biochemistry 2002;41(13):4255-63.
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2002: Notenboom Valerie; Boraston Alisdair B; Williams Spencer J; Kilburn Douglas G; Rose David R
High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding.
Biochemistry 2002;41(13):4246-54.
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2002: Boraston Alisdair B; McLean Bradley W; Chen Grace; Li Anson; Warren R Antony J; Kilburn Douglas G
Co-operative binding of triplicate carbohydrate-binding modules from a thermophilic xylanase.
Molecular microbiology 2002;43(1):187-94.
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2002: Boraston Alisdair B; Ghaffari Mazyar; Warren R Antony J; Kilburn Douglas G
Identification and glucan-binding properties of a new carbohydrate-binding module family.
The Biochemical journal 2002;361(Pt 1):35-40.
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2001: Notenboom V; Boraston A B; Chiu P; Freelove A C; Kilburn D G; Rose D R
Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.
Journal of molecular biology 2001;314(4):797-806.
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2001: Boraston A B; Warren R A; Kilburn D G
beta-1,3-Glucan binding by a thermostable carbohydrate-binding module from Thermotoga maritima.
Biochemistry 2001;40(48):14679-85.
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2001: Boraston A B; Warren R A; Kilburn D G
Glycosylation by Pichia pastoris decreases the affinity of a family 2a carbohydrate-binding module from Cellulomonas fimi: a functional and mutational analysis.
The Biochemical journal 2001;358(Pt 2):423-30.
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2001: Notenboom V; Boraston A B; Kilburn D G; Rose D R
Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.
Biochemistry 2001;40(21):6248-56.
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2001: Boraston A B; Creagh A L; Alam M M; Kormos J M; Tomme P; Haynes C A; Warren R A; Kilburn D G
Binding specificity and thermodynamics of a family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A.
Biochemistry 2001;40(21):6240-7.
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2001: Boraston A B; McLean B W; Guarna M M; Amandaron-Akow E; Kilburn D G
A family 2a carbohydrate-binding module suitable as an affinity tag for proteins produced in Pichia pastoris.
Protein expression and purification 2001;21(3):417-23.
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2000: McLean B W; Bray M R; Boraston A B; Gilkes N R; Haynes C A; Kilburn D G
Analysis of binding of the family 2a carbohydrate-binding module from Cellulomonas fimi xylanase 10A to cellulose: specificity and identification of functionally important amino acid residues.
Protein engineering 2000;13(11):801-9.
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2000: Boraston A B; Chiu P; Warren R A; Kilburn D G
Specificity and affinity of substrate binding by a family 17 carbohydrate-binding module from Clostridium cellulovorans cellulase 5A.
Biochemistry 2000;39(36):11129-36.
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2000: Boraston A B; Tomme P; Amandoron E A; Kilburn D G
A novel mechanism of xylan binding by a lectin-like module from Streptomyces lividans xylanase 10A.
The Biochemical journal 2000;350 Pt 3():933-41.
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2000: Stoll D; Boraston A; Stålbrand H; McLean B W; Kilburn D G; Warren R A
Mannanase Man26A from Cellulomonas fimi has a mannan-binding module.
FEMS microbiology letters 2000;183(2):265-9.
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1998: Tomme P; Boraston A; McLean B; Kormos J; Creagh A L; Sturch K; Gilkes N R; Haynes C A; Warren R A; Kilburn D G
Characterization and affinity applications of cellulose-binding domains.
Journal of chromatography. B, Biomedical sciences and applications 1998;715(1):283-96.
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1998: Bolam D N; Ciruela A; McQueen-Mason S; Simpson P; Williamson M P; Rixon J E; Boraston A; Hazlewood G P; Gilbert H J
Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity.
The Biochemical journal 1998;331 ( Pt 3)():775-81.
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1997: Guarna M M; Lesnicki G J; Tam B M; Robinson J; Radziminski C Z; Hasenwinkle D; Boraston A; Jervis E; Macgillivray R T; Turner R F; Kilburn D G
On-line monitoring and control of methanol concentration in shake-flask cultures of Pichia pastoris.
Biotechnology and bioengineering 1997;56(3):279-86.
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