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Deniz Tasdemir

Research Profile

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TOP 3
Ilkay Erdogan Orhan; Paul Cos; Ali Rifat Gülpinar; Murat Kartal; Louis Maes; An Matheeussen; Deniz Tasdemir
Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of Hypericum perforatum and their LC-DAD-MS analyses.
Néstor M Carballeira; Michelle Cartagena; Christopher F Prada; Rosa M Reguera; David Sanabria; Deniz Tasdemir; Rafael Balaña-Fouce
2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
B Orlikova; M Schnekenburger; Marc Diederich; F Golais; Mire Zloh; Deniz Tasdemir
Natural chalcones as dual inhibitors of HDACs and NF-κB.

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All Publications

2013: Ilkay Erdogan Orhan; Paul Cos; Ali Rifat Gülpinar; Murat Kartal; Louis Maes; An Matheeussen; Deniz Tasdemir
Assessment of antimicrobial and antiprotozoal activity of the olive oil macerate samples of Hypericum perforatum and their LC-DAD-MS analyses.
Food chemistry 2013;138(2-3):870-5.
2012: Néstor M Carballeira; Michelle Cartagena; Christopher F Prada; Rosa M Reguera; David Sanabria; Deniz Tasdemir; Rafael Balaña-Fouce
2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
Bioorganic & medicinal chemistry letters 2012;22(19):6185-9.
2012: B Orlikova; M Schnekenburger; Marc Diederich; F Golais; Mire Zloh; Deniz Tasdemir
Natural chalcones as dual inhibitors of HDACs and NF-κB.
Oncology reports 2012;28(3):797-805.
2011: Barbara Broniatowska; Andrea Allmendinger; Marcel Kaiser; Damien Montamat-Sicotte; Suzie Hingley-Wilson; Ajit Lalvani; Michael Guiry; Gerald Blunden; Deniz Tasdemir
Antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from Ireland.
Natural product communications 2011;6(5):689-94.
2011: Sevda Süzgeç-Selçuk; Ali H Meriçli; Koray Güven; Marcel Kaiser; Rosalyn Casey; Suzie Hingley-Wilson; Ajit Lalvani; Deniz Tasdemir
Evaluation of Turkish seaweeds for antiprotozoal, antimycobacterial and cytotoxic activities.
Phytotherapy research : PTR 2011;25(5):778-83.
2011: Hasan Kirmizibekmez; Irem Atay; Marcel Kaiser; Reto Brun; Michelle M Cartagena; Néstor M Carballeira; Erdem Yesilada; Deniz Tasdemir
Antiprotozoal activity of Melampyrum arvense and its metabolites.
Phytotherapy research : PTR 2011;25(1):142-6.
2010: Deniz Tasdemir; David Sanabria; Ina L Lauinger; Alice Tarun; Rob Herman; Remo Perozzo; Mire Zloh; Stefan Kappe; Reto Brun; Néstor M Carballeira
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.
Bioorganic & medicinal chemistry 2010;18(21):7475-85.
2010: Jasmine Spavieri; Andrea Allmendinger; Marcel Kaiser; Rosalyn Casey; Suzie Hingley-Wilson; Ajit Lalvani; Michael D Guiry; Gerald Blunden; Deniz Tasdemir
Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters.
Phytotherapy research : PTR 2010;24(11):1724-9.
2010: Andrea Allmendinger; Jasmine Spavieri; Marcel Kaiser; Rosalyn Casey; Suzie Hingley-Wilson; Ajit Lalvani; Michael Guiry; Gerald Blunden; Deniz Tasdemir
Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three British and Irish red algae.
Phytotherapy research : PTR 2010;24(7):1099-103.
2010: Jasmine Spavieri; Marcel Kaiser; Rosalyn Casey; Suzie Hingley-Wilson; Ajit Lalvani; Gerald Blunden; Deniz Tasdemir
Antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae.
Phytotherapy research : PTR 2010;24(7):1095-8.
2010: Ilkay Orhan; Bilge Sener; Marcel Kaiser; Reto Brun; Deniz Tasdemir
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa.
Marine drugs 2010;8(1):47-58.
2009: Anastasia Karioti; Helen Skaltsa; Marcel Kaiser; Deniz Tasdemir
Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2009;16(8):783-7.
2009: Kathryn M Marshall; Cynthia D Andjelic; Deniz Tasdemir; Gisela P Concepción; Chris M Ireland; Louis R Barrows
Deoxyamphimedine, a pyridoacridine alkaloid, damages DNA via the production of reactive oxygen species.
Marine drugs 2009;7(2):196-209.
2008: Anastasia Karioti; Helen Skaltsa; Xujie Zhang; Peter J Tonge; Remo Perozzo; Marcel Kaiser; Scott Franzblau; Deniz Tasdemir
Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(12):1125-9.
2008: Deniz Tasdemir; Reto Brun; Scott Franzblau; Yükselen Sezgin; Ihsan Calis
Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(3):209-15.
2007: Alice A Sertan-de Guzman; Rey Z Predicala; Evelyn B Bernardo; Brett A Neilan; Sheila P Elardo; Gina C Mangalindan; Deniz Tasdemir; Chris M Ireland; Wilfredo L Barraquio; Gisela P Concepcion
Pseudovibrio denitrificans strain Z143-1, a heptylprodigiosin-producing bacterium isolated from a Philippine tunicate.
FEMS microbiology letters 2007;277(2):188-96.
2007: Deniz Tasdemir; Bülent Topaloglu; Remo Perozzo; Reto Brun; Rosann O'Neill; Néstor M Carballeira; Xujie Zhang; Peter J Tonge; Anthony Linden; Peter Rüedi
Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli.
Bioorganic & medicinal chemistry 2007;15(21):6834-45.
2007: Anastasia Karioti; Helen Skaltsa; Anthony Linden; Remo Perozzo; Reto Brun; Deniz Tasdemir
Anthecularin: a novel sesquiterpene lactone from Anthemis auriculata with antiprotozoal activity.
The Journal of organic chemistry 2007;72(21):8103-6.
2007: Ihsan Caliş; Yükselen Sezgin; Ali A Dönmez; Peter Rüedi; Deniz Tasdemir
Crypthophilic acids A, B, and C: resin glycosides from aerial parts of Scrophularia crypthophila.
Journal of natural products 2007;70(1):43-7.
2006: Deniz Tasdemir; Reto Brun; Vanessa Yardley; Scott Franzblau; Peter Rüedi
Antituberculotic and antiprotozoal activities of primin, a natural benzoquinone: in vitro and in vivo studies.
Chemistry & biodiversity 2006;3(11):1230-7.
2006: Ilkay Orhan; Mustafa Aslan; Bilge Sener; M Kaiser; Deniz Tasdemir
In vitro antiprotozoal activity of the lipophilic extracts of different parts of Turkish Pistacia vera L.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2006;13(9-10):735-9.
2006: Deniz Tasdemir; Gabriela Lack; Reto Brun; Peter Rüedi; Leonardo Scapozza; Remo Perozzo
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
Journal of medicinal chemistry 2006;49(11):3345-53.
2006: Ilkay Orhan; Bilge Sener; T Atici; Reto Brun; Remo Perozzo; Deniz Tasdemir
Turkish freshwater and marine macrophyte extracts show in vitro antiprotozoal activity and inhibit FabI, a key enzyme of Plasmodium falciparum fatty acid biosynthesis.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2006;13(6):388-93.
2006: Deniz Tasdemir; Marcel Kaiser; Reto Brun; Vanessa Yardley; Thomas Schmidt; Fatma Tosun; Peter Rüedi
Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies.
Antimicrobial agents and chemotherapy 2006;50(4):1352-64.
2005: Meltem Ozipek; Ali A Dönmez; Ihsan Caliş; Reto Brun; Peter Rüedi; Deniz Tasdemir
Leishmanicidal cycloartane-type triterpene glycosides from Astragalus oleifolius.
Phytochemistry 2005;66(10):1168-73.
2005: Deniz Tasdemir; Reto Brun; Remo Perozzo; Ali A Dönmez
Evaluation of antiprotozoal and plasmodial enoyl-ACP reductase inhibition potential of turkish medicinal plants.
Phytotherapy research : PTR 2005;19(2):162-6.
2005: Deniz Tasdemir; Nadide Deniz Güner; Remo Perozzo; Reto Brun; Ali A Dönmez; Ihsan Calis; Peter Rüedi
Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots.
Phytochemistry 2005;66(3):355-62.
2004: Hasan Kirmizibekmez; Ihsan Calis; Remo Perozzo; Reto Brun; Ali A Dönmez; Anthony Linden; Peter Rüedi; Deniz Tasdemir
Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP Reductase, a crucial enzyme in fatty acid biosynthesis.
Planta medica 2004;70(8):711-7.
2004: Rohan A Davis; Gina C Mangalindan; Zenaida P Bojo; Rowena R Antemano; Nell O Rodriguez; Gisela P Concepcion; Shiela C Samson; Dennis de Guzman; Lourdes J Cruz; Deniz Tasdemir; Mary Kay Harper; Xidong Feng; Guy T Carter; Chris M Ireland
Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina.
The Journal of organic chemistry 2004;69(12):4170-6.
2003: Deniz Tasdemir; Betul Demirci; Fatih Demirci; Ali A Dönmez; Kemal Baser; Peter Rüedi
Analysis of the volatile components of five Turkish Rhododendron species by headspace solid-phase microextraction and GC-MS (HS-SPME-GC-MS).
Zeitschrift für Naturforschung. C, Journal of biosciences 2003;58(11-12):797-803.
2003: Kathryn M Marshall; Sandra S Matsumoto; Joseph A Holden; Gisela P Concepción; Deniz Tasdemir; Chris M Ireland; Louis R Barrows
The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine.
Biochemical pharmacology 2003;66(3):447-58.
2003: Sheila Marie V Pimentel; Zenaida P Bojo; Amy Roberto; J Enrico H Lazaro; Gina C Mangalindan; Leila M Florentino; Pilar Lim-Navarro; Deniz Tasdemir; Chris M Ireland; Gisela P Concepcion
Platelet aggregation inhibitors from Philippine marine invertebrate samples screened in a new microplate assay.
Marine biotechnology (New York, N.Y.) 2003;5(4):395-400.
2002: Deniz Tasdemir; Tim S Bugni; Gina C Mangalindan; Gisela P Concepción; Mary Kay Harper; Chris M Ireland
Cytotoxic bromoindole derivatives and terpenes from the Philippine marine sponge Smenospongia sp.
Zeitschrift für Naturforschung. C, Journal of biosciences 2002;57(9-10):914-22.
2002: Ihsan Caliş; Hasan Kirmizibekmez; Deniz Tasdemir; Otto Sticher; Chris M Ireland
Sugar esters from Globularia orientalis.
Zeitschrift für Naturforschung. C, Journal of biosciences 2002;57(7-8):591-6.
2002: Ihsan Caliş; Deniz Tasdemir; Chris M Ireland; Otto Sticher
Lucidin type anthraquinone glycosides from Putoria calabrica.
Chemical & pharmaceutical bulletin 2002;50(5):701-2.
2002: Deniz Tasdemir; Gina C Mangalindan; Gisela P Concepción; Sheryl M Verbitski; Sridhar Rabindran; Miriam Miranda; Michael Greenstein; John N A Hooper; Mary Kay Harper; Chris M Ireland
Bioactive isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata.
Journal of natural products 2002;65(2):210-4.
2002: Deniz Tasdemir; Robert Mallon; Michael Greenstein; Larry Feldberg; Steven C Kim; Karen Collins; Donald Wojciechowicz; Gina C Mangalindan; Gisela P Concepción; Mary Kay Harper; Chris M Ireland
Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).
Journal of medicinal chemistry 2002;45(2):529-32.
2001: Deniz Tasdemir; Gina C Mangalindan; Gisela P Concepción; Mary Kay Harper; Chris M Ireland
3,7-Dimethylguanine, a new purine from a Philippine sponge Zyzzya fuliginosa.
Chemical & pharmaceutical bulletin 2001;49(12):1628-30.
2001: Ihsan Calis; J Heilmann; Deniz Tasdemir; Anthony Linden; Chris M Ireland; Otto Sticher
Flavonoid, iridoid, and lignan glycosides from Putoria calabrica.
Journal of natural products 2001;64(7):961-4.
2001: Deniz Tasdemir; Kathryn M Marshall; Gina C Mangalindan; Gisela P Concepción; Louis R Barrows; Mary Kay Harper; Chris M Ireland
Deoxyamphimedine, a new pyridoacridine alkaloid from two tropical Xestospongia sponges.
The Journal of organic chemistry 2001;66(9):3246-8.
1999: Deniz Tasdemir; Leonardo Scapozza; Oliver Zerbe; A Linden; Ihsan Calis; Otto Sticher
Iridoid glycosides of Leonurus persicus.
Journal of natural products 1999;62(6):811-6.
1998: Tülay Baykal; T Panayir; Deniz Tasdemir; Otto Sticher; Ihsan Calis
Triterpene saponins from Scabiosa rotata.
Phytochemistry 1998;48(5):867-73.