Kjetil Taskén

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Torheim Eirik A; Jarnaess Elisabeth; Lygren Birgitte; Taskén Kjetil
Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.
Taskén Kjetil
Waking up regulatory T cells.
Torheim Eirik A; Ndhlovu Lishomwa C; Pettersen Frank O; Larsen Trine-Lise; Jha Aashish R; Torgersen Knut M; Kvale Dag; Nixon Douglas F; Taskén Kjetil; Aandahl Einar M
Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

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2009: Torheim Eirik A; Jarnaess Elisabeth; Lygren Birgitte; Taskén Kjetil
Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.
The Biochemical journal 2009;424(1):69-78.
2009: Taskén Kjetil
Waking up regulatory T cells.
Blood 2009;114(6):1136-7.
2009: Torheim Eirik A; Ndhlovu Lishomwa C; Pettersen Frank O; Larsen Trine-Lise; Jha Aashish R; Torgersen Knut M; Kvale Dag; Nixon Douglas F; Taskén Kjetil; Aandahl Einar M
Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.
European journal of immunology 2009;39(5):1280-7.
2009: Rogne Marie; Stokka Anne Jorunn; Taskén Kjetil; Collas Philippe; Küntziger Thomas
Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.
Human molecular genetics 2009;18(5):978-87.
2009: Ngai Jacob; Inngjerdingen Marit; Berge Torunn; Taskén Kjetil
Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation.
BMC immunology 2009;10():27.
2008: Ngai Jacob; Methi Trond; Andressen Kjetil Wessel; Levy Finn Olav; Torgersen Knut Martin; Vang Torkel; Wettschureck Nina; Taskén Kjetil
The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway.
European journal of immunology 2008;38(11):3208-18.
2008: Aandahl Einar Martin; Torgersen Knut Martin; Taskén Kjetil
CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?
Human immunology 2008;69(11):696-9.
2008: Mahic M; Kalland M E; Aandahl E M; Torgersen K M; Taskén K
Human naturally occurring and adaptive regulatory T cells secrete high levels of leukaemia inhibitory factor upon activation.
Scandinavian journal of immunology 2008;68(4):391-6.
2008: Solheim Silje A; Petsalaki Evangelia; Stokka Anne J; Russell Robert B; Taskén Kjetil; Berge Torunn
Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity.
The FEBS journal 2008;275(19):4863-74.
2008: Larsen Karl-Otto; Lygren Birgitte; Sjaastad Ivar; Krobert Kurt A; Arnkvaern Kristin; Florholmen Geir; Larsen Ann-Kristin Ruud; Levy Finn Olav; Taskén Kjetil; Skjønsberg Ole Henning; Christensen Geir
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A.
Cardiovascular research 2008;80(1):47-54.
2008: Methi Trond; Berge Torunn; Torgersen Knut Martin; Taskén Kjetil
Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels.
European journal of immunology 2008;38(9):2557-63.
2008: Lygren Birgitte; Taskén Kjetil
The potential use of AKAP18delta as a drug target in heart failure patients.
Expert opinion on biological therapy 2008;8(8):1099-108.
2008: Bryn Tone; Mahic Milada; Aandahl Einar M; Frøland Stig S; Aukrust Pål; Taskén Kjetil
Inhibition of protein kinase A improves effector function of monocytes from HIV-infected patients.
AIDS research and human retroviruses 2008;24(7):1013-5.
2008: Yaqub Sheraz; Henjum Karen; Mahic Milada; Jahnsen Frode L; Aandahl Einar M; Bjørnbeth Bjørn A; Taskén Kjetil
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner.
Cancer immunology, immunotherapy : CII 2008;57(6):813-21.
2008: Mahic Milada; Yaqub Sheraz; Bryn Tone; Henjum Karen; Eide Dag M; Torgersen Knut M; Aandahl Einar M; Taskén Kjetil
Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.
Journal of leukocyte biology 2008;83(5):1111-7.
2008: Mahic Milada; Henjum Karen; Yaqub Sheraz; Bjørnbeth Bjørn Atle; Torgersen Knut Martin; Taskén Kjetil; Aandahl Einar Martin
Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation.
European journal of immunology 2008;38(3):640-6.
2008: Bryn Tone; Yaqub Sheraz; Mahic Milada; Henjum Karen; Aandahl Einar M; Taskén Kjetil
LPS-activated monocytes suppress T-cell immune responses and induce FOXP3+ T cells through a COX-2-PGE2-dependent mechanism.
International immunology 2008;20(2):235-45.
2008: Solheim Silje Anette; Torgersen Knut Martin; Taskén Kjetil; Berge Torunn
Regulation of FynT function by dual domain docking on PAG/Cbp.
The Journal of biological chemistry 2008;283(5):2773-83.
2007: Jarnaess E; Taskén K
Spatiotemporal control of cAMP signalling processes by anchored signalling complexes.
Biochemical Society transactions 2007;35(Pt 5):931-7.
2007: Lygren Birgitte; Carlson Cathrine Rein; Santamaria Katja; Lissandron Valentina; McSorley Theresa; Litzenberg Jessica; Lorenz Dorothea; Wiesner Burkhard; Rosenthal Walter; Zaccolo Manuela; Taskén Kjetil; Klussmann Enno
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum.
EMBO reports 2007;8(11):1061-7.
2007: Ruppelt Anja; Mosenden Randi; Grönholm Mikaela; Aandahl Einar M; Tobin Derek; Carlson Cathrine R; Abrahamsen Hilde; Herberg Friedrich W; Carpén Olli; Taskén Kjetil
Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5159-68.
2007: Methi Trond; Ngai Jacob; Vang Torkel; Torgersen Knut M; Taskén Kjetil
Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.
European journal of immunology 2007;37(9):2539-48.
2007: Kesti Tapio; Ruppelt Anja; Wang Jing-Huan; Liss Michael; Wagner Ralf; Taskén Kjetil; Saksela Kalle
Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):878-85.
2007: Andrei Mioara; Bjørnstad Vidar; Langli Geir; Rømming Christian; Klaveness Jo; Taskén Kjetil; Undheim Kjell
Stereoselective preparation of (RP)-8-hetaryladenosine-3',5'-cyclic phosphorothioic acids.
Organic & biomolecular chemistry 2007;5(13):2070-80.
2007: Damås Jan K; Smith Camilla; Øie Erik; Fevang Børre; Halvorsen Bente; Waehre Torgun; Boullier Agnes; Breland Unni; Yndestad Arne; Ovchinnikova Olga; Robertson Anna-Karin L; Sandberg Wiggo J; Kjekshus John; Taskén Kjetil; Frøland Stig S; Gullestad Lars; Hansson Göran K; Quehenberger Oswald; Aukrust Pål
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):614-20.
2007: Kvissel Anne-Katrine; Ramberg Håkon; Eide Turid; Svindland Aud; Skålhegg Bjørn Steen; Taskén Kristin Austlid
Androgen dependent regulation of protein kinase A subunits in prostate cancer cells.
Cellular signalling 2007;19(2):401-9.
2006: Stokka Anne J; Gesellchen Frank; Carlson Cathrine R; Scott John D; Herberg Friedrich W; Taskén Kjetil
Characterization of A-kinase-anchoring disruptors using a solution-based assay.
The Biochemical journal 2006;400(3):493-9.
2006: Gold Matthew G; Lygren Birgitte; Dokurno Pawel; Hoshi Naoto; McConnachie George; Taskén Kjetil; Carlson Cathrine R; Scott John D; Barford David
Molecular basis of AKAP specificity for PKA regulatory subunits.
Molecular cell 2006;24(3):383-95.
2006: Lygren B; Taskén K
Compartmentalized cAMP signalling is important in the regulation of Ca(2+) cycling in the heart.
Biochemical Society transactions 2006;34(Pt 4):489-91.
2006: Taskén K; Stokka A J
The molecular machinery for cAMP-dependent immunomodulation in T-cells.
Biochemical Society transactions 2006;34(Pt 4):476-9.
2006: Grønning Line M; Baillie George S; Cederberg Anna; Lynch Martin J; Houslay Miles D; Enerbäck Sven; Taskén Kjetil
Reduced PDE4 expression and activity contributes to enhanced catecholamine-induced cAMP accumulation in adipocytes from FOXC2 transgenic mice.
FEBS letters 2006;580(17):4126-30.
2006: Mahic Milada; Yaqub Sheraz; Johansson C Christian; Taskén Kjetil; Aandahl Einar M
FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):246-54.
2006: Carlson Cathrine Rein; Lygren Birgitte; Berge Torunn; Hoshi Naoto; Wong Wei; Taskén Kjetil; Scott John D
Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor.
The Journal of biological chemistry 2006;281(30):21535-45.
2006: Bryn Tone; Mahic Milada; Enserink Jorrit M; Schwede Frank; Aandahl Einar Martin; Taskén Kjetil
The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7361-70.
2006: Kvale Dag; Ormaasen Vidar; Kran Anne-Marte Bakken; Johansson Carl Christian; Aukrust Pål; Aandahl Einar Martin; Frøland Stig S; Taskén Kjetil
Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatment.
AIDS (London, England) 2006;20(6):813-20.
2006: Bjørgo Elisa; Taskén Kjetil
Role of cAMP phosphodiesterase 4 in regulation of T-cell function.
Critical reviews in immunology 2006;26(5):443-51.
2005: Taskén Kristin Austlid; Angelsen Anders; Svindland Aud; Eide Turid; Berge Viktor; Wahlquist Rolf; Karlsen Steinar
[Markers for diagnosis, prediction and prognosis of prostate cancer]
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2005;125(23):3279-82.
2005: Vang Torkel; Congia Mauro; Macis Maria Doloretta; Musumeci Lucia; Orrú Valeria; Zavattari Patrizia; Nika Konstantina; Tautz Lutz; Taskén Kjetil; Cucca Francesco; Mustelin Tomas; Bottini Nunzio
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant.
Nature genetics 2005;37(12):1317-9.
2005: Lygren Birgitte; Taskén Kjetil; Carlson Cathrine R
A fast and sensitive method for isolation of detergent-resistant membranes from T cells.
Journal of immunological methods 2005;305(2):199-205.
2004: Waehre Torgun; Damås Jan Kristian; Yndestad Arne; Taskén Kjetil; Pedersen Turid M; Smith Camilla; Halvorsen Bente; Frøland Stig S; Solum Nils O; Aukrust Pål
Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells - potential role of prostaglandin E2.
Thrombosis and haemostasis 2004;92(6):1358-67.
2004: Johansson C Christian; Yndestad Arne; Enserink Jorrit M; Ree Anne H; Aukrust Pål; Taskén Kjetil
The epidermal growth factor-like growth factor amphiregulin is strongly induced by the adenosine 3',5'-monophosphate pathway in various cell types.
Endocrinology 2004;145(11):5177-84.
2004: Abrahamsen Hilde; Baillie George; Ngai Jacob; Vang Torkel; Nika Konstantina; Ruppelt Anja; Mustelin Tomas; Zaccolo Manuela; Houslay Miles; Taskén Kjetil
TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):4847-58.
2004: Enserink Jorrit M; Price Leo S; Methi Trond; Mahic Milada; Sonnenberg Arnoud; Bos Johannes L; Taskén Kjetil
The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin.
The Journal of biological chemistry 2004;279(43):44889-96.
2004: Johansson C Christian; Bryn Tone; Aandahl Einar M; Areklett Maria A; Aukrust Pål; Taskén Kjetil; Frøland Stig S
Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy.
AIDS (London, England) 2004;18(6):951-2.
2004: Nika Konstantina; Hyunh Huong; Williams Scott; Paul Surojit; Bottini Nunzio; Taskén Kjetil; Lombroso Paul J; Mustelin Tomas
Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.
The Biochemical journal 2004;378(Pt 2):335-42.
2004: Johansson C Christian; Bryn Tone; Yndestad Arne; Eiken Hans Geir; Bjerkeli Vigdis; Frøland Stig S; Aukrust Pål; Taskén Kjetil
Cytokine networks are pre-activated in T cells from HIV-infected patients on HAART and are under the control of cAMP.
AIDS (London, England) 2004;18(2):171-9.
2004: Taskén Kjetil; Aandahl Einar Martin
Localized effects of cAMP mediated by distinct routes of protein kinase A.
Physiological reviews 2004;84(1):137-67.
2003: Grönholm Mikaela; Vossebein Lutz; Carlson Cathrine R; Kuja-Panula Juha; Teesalu Tambet; Alfthan Kaija; Vaheri Antti; Rauvala Heikki; Herberg Friedrich W; Taskén Kjetil; Carpén Olli
Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.
The Journal of biological chemistry 2003;278(42):41167-72.
2003: Eide Turid; Taskén Kristin A; Carlson Cathrine; Williams Gareth; Jahnsen Tore; Taskén Kjetil; Collas Philippe
Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication.
The Journal of biological chemistry 2003;278(29):26750-6.
2003: Eide Turid; Taskén Kristin A; Carlson Cathrine; Williams Gareth; Jahnsen Tore; Taskén Kjetil; Collas Philippe
Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication.
The Journal of biological chemistry 2003;278(29):26750-6.
2003: Holm Are Martin; Aukrust Pål; Aandahl Einar Martin; Müller Fredrik; Taskén Kjetil; Frøland Stig S
Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5772-7.
2003: Vang Torkel; Abrahamsen Hilde; Myklebust Sondre; Horejsí Václav; Taskén Kjetil
Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling.
The Journal of biological chemistry 2003;278(20):17597-600.
2003: Johansson C Christian; Dahle Maria K; Blomqvist Sandra Rodrigo; Grønning Line M; Aandahl Einar M; Enerbäck Sven; Taskén Kjetil
A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha.
The Journal of biological chemistry 2003;278(19):17573-9.
2003: Abrahamsen Hilde; Vang Torkel; Taskén Kjetil
Protein kinase A intersects SRC signaling in membrane microdomains.
The Journal of biological chemistry 2003;278(19):17170-7.
2003: Yaqub Sheraz; Abrahamsen Hilde; Zimmerman Bastian; Kholod Natalya; Torgersen Knut Martin; Mustelin Tomas; Herberg Friedrich W; Taskén Kjetil; Vang Torkel
Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain.
The Biochemical journal 2003;372(Pt 1):271-8.
2003: Mustelin Tomas; Taskén Kjetil
Positive and negative regulation of T-cell activation through kinases and phosphatases.
The Biochemical journal 2003;371(Pt 1):15-27.
2003: Yaqub Sheraz; Solhaug Vigdis; Vang Torkel; Solberg Rigmor; Aasen Ansgar; Taskén Kjetil; Wang Jacob E
A human whole blood model of LPS-mediated suppression of T cell activation.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(3):BR120-6.
2003: Carlson Cathrine R; Ruppelt Anja; Taskén Kjetil
A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system.
Journal of molecular biology 2003;327(3):609-18.
2003: Aandahl Einar M; Sandberg Johan K; Beckerman Karen P; Taskén Kjetil; Moretto Walter J; Nixon Douglas F
CD7 is a differentiation marker that identifies multiple CD8 T cell effector subsets.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2349-55.
2003: Birkeli Kim Are; Llorente Alicia; Torgersen Maria L; Keryer Guy; Taskén Kjetil; Sandvig Kirsten
Endosome-to-Golgi transport is regulated by protein kinase A type II alpha.
The Journal of biological chemistry 2003;278(3):1991-7.
2002: Dahle Maria Krudtaa; Taskén Kjetil; Taskén Kristin Austlid
USF2 inhibits C/EBP-mediated transcriptional regulation of the RIIbeta subunit of cAMP-dependent protein kinase.
BMC molecular biology 2002;3():10.
2002: Dahle Maria Krudtaa; Taskén Kjetil; Taskén Kristin Austlid
USF2 inhibits C/EBP-mediated transcriptional regulation of the RIIbeta subunit of cAMP-dependent protein kinase.
BMC molecular biology 2002;3():10.
2002: Dahle Maria K; Grønning Line M; Cederberg Anna; Blomhoff Heidi Kiil; Miura Naoyuki; Enerbäck Sven; Taskén Kristin A; Taskén Kjetil
Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.
The Journal of biological chemistry 2002;277(25):22902-8.
2002: Dahle Maria K; Grønning Line M; Cederberg Anna; Blomhoff Heidi Kiil; Miura Naoyuki; Enerbäck Sven; Taskén Kristin A; Taskén Kjetil
Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.
The Journal of biological chemistry 2002;277(25):22902-8.
2002: Eide Turid; Carlson Cathrine; Taskén Kristin A; Hirano Tatsuya; Taskén Kjetil; Collas Philippe
Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting.
EMBO reports 2002;3(5):426-32.
2002: Eide Turid; Carlson Cathrine; Taskén Kristin A; Hirano Tatsuya; Taskén Kjetil; Collas Philippe
Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting.
EMBO reports 2002;3(5):426-32.
2002: Grønning Line M; Cederberg Anna; Miura Naoyuki; Enerbäck Sven; Taskén Kjetil
Insulin and TNF alpha induce expression of the forkhead transcription factor gene Foxc2 in 3T3-L1 adipocytes via PI3K and ERK 1/2-dependent pathways.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):873-83.
2002: Hoover Frank; Kalhovde John M; Dahle Maria Krudtaa; Skålhegg Bjørn; Taskén Kjetil; Lømo Terje
Electrical muscle activity pattern and transcriptional and posttranscriptional mechanisms regulate PKA subunit expression in rat skeletal muscle.
Molecular and cellular neurosciences 2002;19(2):125-37.
2002: Torgersen Knut Martin; Vang Torkel; Abrahamsen Hilde; Yaqub Sheraz; Taskén Kjetil
Molecular mechanisms for protein kinase A-mediated modulation of immune function.
Cellular signalling 2002;14(1):1-9.
2001: Dahle M K; Knutsen H K; Taskén K A; Pilz R; Taskén K
Cyclic AMP regulates expression of the RI alpha subunit of cAMP-dependent protein kinase through an alternatively spliced 5' UTR.
European journal of biochemistry / FEBS 2001;268(22):5920-9.
2001: Dahle M K; Knutsen H K; Taskén K A; Pilz R; Taskén K
Cyclic AMP regulates expression of the RI alpha subunit of cAMP-dependent protein kinase through an alternatively spliced 5' UTR.
European journal of biochemistry / FEBS 2001;268(22):5920-9.
2001: Landsverk H B; Carlson C R; Steen R L; Vossebein L; Herberg F W; Taskén K; Collas P
Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis.
Journal of cell science 2001;114(Pt 18):3255-64.
2001: Carlson C R; Witczak O; Vossebein L; Labbé J C; Skålhegg B S; Keryer G; Herberg F W; Collas P; Taskén K
CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis.
Journal of cell science 2001;114(Pt 18):3243-54.
2001: Cederberg A; Grønning L M; Ahrén B; Taskén K; Carlsson P; Enerbäck S
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance.
Cell 2001;106(5):563-73.
2001: Torgersen K M; Vang T; Abrahamsen H; Yaqub S; Horejsí V; Schraven B; Rolstad B; Mustelin T; Taskén K
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.
The Journal of biological chemistry 2001;276(31):29313-8.
2001: Rahmouni S; Aandahl E M; Trebak M; Boniver J; Taskén K; Moutschen M
Increased cAMP levels and protein kinase (PKA) type I activation in CD4+ T cells and B cells contribute to retrovirus-induced immunodeficiency of mice (MAIDS): a useful in vivo model for drug testing.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(8):1466-8.
2001: Taskén K A; Collas P; Kemmner W A; Witczak O; Conti M; Taskén K
Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area.
The Journal of biological chemistry 2001;276(25):21999-2002.
2001: Taskén K A; Collas P; Kemmner W A; Witczak O; Conti M; Taskén K
Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area.
The Journal of biological chemistry 2001;276(25):21999-2002.
2001: Dahle M K; Reinton N; Orstavik S; Taskén K A; Taskén K
Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expression.
Molecular reproduction and development 2001;59(1):11-6.
2001: Dahle M K; Reinton N; Orstavik S; Taskén K A; Taskén K
Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expression.
Molecular reproduction and development 2001;59(1):11-6.
2001: Hoover F; Mathiesen I; Skålhegg B S; Lømo T; Taskén K
Differential expression and regulation of the PKA signalling pathway in fast and slow skeletal muscle.
Anatomy and embryology 2001;203(3):193-201.
2001: Torgersen K M; Vaage J T; Rolstad B; Taskén K
A soluble LAT deletion mutant inhibits T-cell activation: reduced recruitment of signalling molecules to glycolipid-enriched microdomains.
Cellular signalling 2001;13(3):213-20.
2001: Vang T; Torgersen K M; Sundvold V; Saxena M; Levy F O; Skålhegg B S; Hansson V; Mustelin T; Taskén K
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor.
The Journal of experimental medicine 2001;193(4):497-507.
2000: Steen R L; Martins S B; Taskén K; Collas P
Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly.
The Journal of cell biology 2000;150(6):1251-62.
2000: Reinton N; Orstavik S; Haugen T B; Jahnsen T; Taskén K; Skålhegg B S
A novel isoform of human cyclic 3',5'-adenosine monophosphate-dependent protein kinase, c alpha-s, localizes to sperm midpiece.
Biology of reproduction 2000;63(2):607-11.
2000: Reinton N; Collas P; Haugen T B; Skâlhegg B S; Hansson V; Jahnsen T; Taskén K
Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis.
Developmental biology 2000;223(1):194-204.
2000: Hansson V; Skålhegg B S; Taskén K
Cyclic-AMP-dependent protein kinase (PKA) in testicular cells. Cell specific expression, differential regulation and targeting of subunits of PKA.
The Journal of steroid biochemistry and molecular biology 2000;73(1-2):81-92.
2000: Grønning L M; Wang J E; Ree A H; Haugen T B; Taskén K; Taskén K A
Regulation of tissue inhibitor of metalloproteinases-1 in rat Sertoli cells: induction by germ cell residual bodies, interleukin-1alpha, and second messengers.
Biology of reproduction 2000;62(4):1040-6.
2000: Grønning L M; Wang J E; Ree A H; Haugen T B; Taskén K; Taskén K A
Regulation of tissue inhibitor of metalloproteinases-1 in rat Sertoli cells: induction by germ cell residual bodies, interleukin-1alpha, and second messengers.
Biology of reproduction 2000;62(4):1040-6.
2000: Taskén K; Hansson V; Aukrust P; Frøland S; Skålhegg B S; Müller F; Tobin D; Vang T; Torgersen K M; Aandahl E M
PKAI as a potential target for therapeutic intervention.
Drug news & perspectives 2000;13(1):12-8.
2000: Orstavik S; Eide T; Collas P; Han I O; Taskén K; Kieff E; Jahnsen T; Skålhegg B S
Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95.
Biology of the cell / under the auspices of the European Cell Biology Organization 2000;92(1):27-37.
1999: Collas P; Le Guellec K; Taskén K
The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis.
The Journal of cell biology 1999;147(6):1167-80.
1999: Aandahl E M; Aukrust P; Müller F; Hansson V; Taskén K; Frøland S S
Additive effects of IL-2 and protein kinase A type I antagonist on function of T cells from HIV-infected patients on HAART.
AIDS (London, England) 1999;13(17):F109-14.
1999: Gronning L M; Knutsen H K; Eskild W; Hansson V; Taskén K; Taskén K A
Method of transfection affects the cAMP-mediated induction of the RIIbeta subunit of protein kinase A in Sertoli cells: inhibition of response by increase in intracellullar calcium.
European journal of endocrinology / European Federation of Endocrine Societies 1999;141(1):75-82.
1999: Gronning L M; Knutsen H K; Eskild W; Hansson V; Taskén K; Taskén K A
Method of transfection affects the cAMP-mediated induction of the RIIbeta subunit of protein kinase A in Sertoli cells: inhibition of response by increase in intracellullar calcium.
European journal of endocrinology / European Federation of Endocrine Societies 1999;141(1):75-82.
1999: Keryer G; Skålhegg B S; Landmark B F; Hansson V; Jahnsen T; Taskén K
Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area.
Experimental cell research 1999;249(1):131-46.
1999: Ree A H; Hansson V; Walaas S I; Eskild W; Taskén K A
Calcium/phospholipid-dependent protein kinases in rat Sertoli cells: regulation of androgen receptor messenger ribonucleic acid.
Biology of reproduction 1999;60(5):1257-62.
1999: Hansson V; Skålhegg B S; Taskén K
Cyclic-AMP-dependent protein kinase (PKA) in testicular cells. Cell specific expression, differential regulation and targeting of subunits of PKA.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):367-78.
1999: Witczak O; Skålhegg B S; Keryer G; Bornens M; Taskén K; Jahnsen T; Orstavik S
Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.
The EMBO journal 1999;18(7):1858-68.
1999: Grønning L M; Dahle M K; Taskén K A; Enerbäck S; Hedin L; Taskén K; Knutsen H K
Isoform-specific regulation of the CCAAT/enhancer-binding protein family of transcription factors by 3',5'-cyclic adenosine monophosphate in Sertoli cells.
Endocrinology 1999;140(2):835-43.
1999: Grønning L M; Dahle M K; Taskén K A; Enerbäck S; Hedin L; Taskén K; Knutsen H K
Isoform-specific regulation of the CCAAT/enhancer-binding protein family of transcription factors by 3',5'-cyclic adenosine monophosphate in Sertoli cells.
Endocrinology 1999;140(2):835-43.
1999: Aukrust P; Aandahl E M; Skålhegg B S; Nordøy I; Hansson V; Taskén K; Frøland S S; Müller F
Increased activation of protein kinase A type I contributes to the T cell deficiency in common variable immunodeficiency.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1178-85.
1998: Keryer G; Yassenko M; Labbé J C; Castro A; Lohmann S M; Evain-Brion D; Taskén K
Mitosis-specific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase.
The Journal of biological chemistry 1998;273(51):34594-602.
1998: Skålhegg B S; Johansen A K; Levy F O; Andersson K B; Aandahl E M; Blomhoff H K; Hansson V; Taskén K
Isozymes of cyclic AMP-dependent protein kinases (PKA) in human lymphoid cell lines: levels of endogenous cAMP influence levels of PKA subunits and growth in lymphoid cell lines.
Journal of cellular physiology 1998;177(1):85-93.
1998: Aandahl E M; Aukrust P; Skålhegg B S; Müller F; Frøland S S; Hansson V; Taskén K
Protein kinase A type I antagonist restores immune responses of T cells from HIV-infected patients.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(10):855-62.
1998: Taskén K; Naylor S L; Solberg R; Jahnsen T
Mapping of the gene encoding the regulatory subunit RII alpha of cAMP-dependent protein kinase (locus PRKAR2A) to human chromosome region 3p21.3-p21.2.
Genomics 1998;50(3):378-81.
1998: Vang T; Taskén K; Skålhegg B S; Hansson V; Levy F O
Kinetic properties of the C-terminal Src kinase, p50csk.
Biochimica et biophysica acta 1998;1384(2):285-93.
1998: Reinton N; Haugen T B; Orstavik S; Skålhegg B S; Hansson V; Jahnsen T; Taskén K
The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon.
Genomics 1998;49(2):290-7.
1998: Weber J R; Orstavik S; Torgersen K M; Danbolt N C; Berg S F; Ryan J C; Taskén K; Imboden J B; Vaage J T
Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells.
The Journal of experimental medicine 1998;187(7):1157-61.
1998: Skarpen E; Thoresen G H; Taskén K; Samuelsen J T; Jahnsen T; Schwarze P E; Huitfeldt H S
Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis.
Histochemistry and cell biology 1998;109(3):203-9.
1998: Eide T; Coghlan V; Orstavik S; Holsve C; Solberg R; Skâlhegg B S; Lamb N J; Langeberg L; Fernandez A; Scott J D; Jahnsen T; Taskén K
Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95.
Experimental cell research 1998;238(2):305-16.
1997: Skålhegg B S; Taskén K
Specificity in the cAMP/PKA signaling pathway. differential expression, regulation, and subcellular localization of subunits of PKA.
Frontiers in bioscience : a journal and virtual library 1997;2():d331-42.
1997: Orstavik S; Natarajan V; Taskén K; Jahnsen T; Sandberg M
Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1).
Genomics 1997;42(2):311-8.
1997: Knutsen H K; Taskén K; Eskild W; Richards J S; Kurten R C; Torjesen P A; Jahnsen T; Hansson V; Guérin S; Taskén K A
Characterization of the 5'-flanking region of the gene for the cAMP-inducible protein kinase A subunit, RIIbeta, in Sertoli cells.
Molecular and cellular endocrinology 1997;129(1):101-14.
1997: Knutsen H K; Taskén K; Eskild W; Richards J S; Kurten R C; Torjesen P A; Jahnsen T; Hansson V; Guérin S; Taskén K A
Characterization of the 5'-flanking region of the gene for the cAMP-inducible protein kinase A subunit, RIIbeta, in Sertoli cells.
Molecular and cellular endocrinology 1997;129(1):101-14.
1997: Torgersen K M; Vaage J T; Levy F O; Hansson V; Rolstad B; Taskén K
Selective activation of cAMP-dependent protein kinase type I inhibits rat natural killer cell cytotoxicity.
The Journal of biological chemistry 1997;272(9):5495-500.
1997: Foss K B; Solberg R; Simard J; Myklebust F; Hansson V; Jahnsen T; Taskén K
Molecular cloning, upstream sequence and promoter studies of the human gene for the regulatory subunit RII alpha of cAMP-dependent protein kinase.
Biochimica et biophysica acta 1997;1350(1):98-108.
1997: Solberg R; Sandberg M; Natarajan V; Torjesen P A; Hansson V; Jahnsen T; Taskén K
The human gene for the regulatory subunit RI alpha of cyclic adenosine 3', 5'-monophosphate-dependent protein kinase: two distinct promoters provide differential regulation of alternately spliced messenger ribonucleic acids.
Endocrinology 1997;138(1):169-81.
1997: Taskén K; Skålhegg B S; Taskén K A; Solberg R; Knutsen H K; Levy F O; Sandberg M; Orstavik S; Larsen T; Johansen A K; Vang T; Schrader H P; Reinton N T; Torgersen K M; Hansson V; Jahnsen T
Structure, function, and regulation of human cAMP-dependent protein kinases.
Advances in second messenger and phosphoprotein research 1997;31():191-204.
1997: Taskén K; Skålhegg B S; Taskén K A; Solberg R; Knutsen H K; Levy F O; Sandberg M; Orstavik S; Larsen T; Johansen A K; Vang T; Schrader H P; Reinton N T; Torgersen K M; Hansson V; Jahnsen T
Structure, function, and regulation of human cAMP-dependent protein kinases.
Advances in second messenger and phosphoprotein research 1997;31():191-204.
1996: Taskén K; Solberg R; Zhao Y; Hansson V; Jahnsen T; Siciliano M J
The gene encoding the catalytic subunit C alpha of cAMP-dependent protein kinase (locus PRKACA) localizes to human chromosome region 19p13.1.
Genomics 1996;36(3):535-8.
1996: Levy F O; Taskén K; Hansson V
Report on the 9th European Workshop on the Molecular and Cellular Endocrinology of the Testis.
Molecular and cellular endocrinology 1996;122(1):1-13.
1996: Knutsen H K; Reinton N; Taskén K A; Hansson V; Eskild W
Regulation of protein kinase A subunits by cyclic adenosine 3',5'-monophosphate in a mouse Sertoli cell line (MSC-1): induction of RII beta messenger ribonucleic acid is independent of continuous protein synthesis.
Biology of reproduction 1996;55(1):5-10.
1996: Levy F O; Rasmussen A M; Taskén K; Skålhegg B S; Huitfeldt H S; Funderud S; Smeland E B; Hansson V
Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation.
European journal of immunology 1996;26(6):1290-6.
1996: Orstavik S; Solberg R; Taskén K; Nordahl M; Altherr M R; Hansson V; Jahnsen T; Sandberg M
Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase.
Biochemical and biophysical research communications 1996;220(3):759-65.
1996: Hansson V; Skålhegg B S; Taskén K
Is basic endocrinology disappearing?
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(1):7-8.
1995: Taskén K A; Jacobsen F W; Eikvar L; Hansson V; Haugen T B
The alpha-subunit mRNAs for Gs and Go2 are differentially regulated by protein kinase A and protein kinase C in rat Sertoli cells.
Biochimica et biophysica acta 1995;1260(3):269-75.
1994: Berg J P; Ree A H; Sandvik J A; Taskén K; Landmark B F; Torjesen P A; Haug E
1,25-dihydroxyvitamin D3 alters the effect of cAMP in thyroid cells by increasing the regulatory subunit type II beta of the cAMP-dependent protein kinase.
The Journal of biological chemistry 1994;269(51):32233-8.
1994: Taskén K; Andersson K B; Erikstein B K; Hansson V; Jahnsen T; Blomhoff H K
Regulation of growth in a neoplastic B cell line by transfected subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinase.
Endocrinology 1994;135(5):2109-19.
1994: Solberg R; Taskén K; Wen W; Coghlan V M; Meinkoth J L; Scott J D; Jahnsen T; Taylor S S
Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells.
Experimental cell research 1994;214(2):595-605.
1994: Skålhegg B S; Rasmussen A M; Taskén K; Hansson V; Jahnsen T; Lea T
Cyclic AMP sensitive signalling by the CD28 marker requires concomitant stimulation by the T-cell antigen receptor (TCR/CD3) complex.
Scandinavian journal of immunology 1994;40(2):201-8.
1994: Levy F O; Holtgreve-Grez H; Taskén K; Solberg R; Ried T; Gudermann T
Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15.
Genomics 1994;22(3):637-40.
1994: Christoffersen J; Smeland E B; Stokke T; Taskén K; Andersson K B; Blomhoff H K
Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells.
Cancer research 1994;54(8):2245-50.
1994: Foss K B; Landmark B; Skålhegg B S; Taskén K; Jellum E; Hansson V; Jahnsen T
Characterization of in-vitro-translated human regulatory and catalytic subunits of cAMP-dependent protein kinases.
European journal of biochemistry / FEBS 1994;220(1):217-23.
1994: Andersson K B; Taskén K; Blomhoff H K
Cyclic AMP downregulates c-myc expression by inhibition of transcript initiation in human B-precursor Reh cells.
FEBS letters 1994;337(1):71-6.
1994: Skålhegg B S; Taskén K; Hansson V; Huitfeldt H S; Jahnsen T; Lea T
Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex.
Science (New York, N.Y.) 1994;263(5143):84-7.
1994: Ree A H; Taskén K; Hansson V
Regulation of glucocorticoid receptor (GR) mRNA and protein levels by phorbol ester in MCF-7 cells. Mechanism of GR mRNA induction and decay.
The Journal of steroid biochemistry and molecular biology 1994;48(1):23-9.
1993: Taskén K; Andersson K B; Skålhegg B S; Taskén K A; Hansson V; Jahnsen T; Blomhoff H K
Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh).
The Journal of biological chemistry 1993;268(31):23483-9.
1993: Taskén K; Andersson K B; Skålhegg B S; Taskén K A; Hansson V; Jahnsen T; Blomhoff H K
Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh).
The Journal of biological chemistry 1993;268(31):23483-9.
1993: Taskén K; Skålhegg B S; Solberg R; Andersson K B; Taylor S S; Lea T; Blomhoff H K; Jahnsen T; Hansson V
Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes.
The Journal of biological chemistry 1993;268(28):21276-83.
1993: Eikvar L; Taskén K A; Eskild W; Hansson V
Protein kinase C activation and positive and negative agonist regulation of 3',5'-cyclic adenosine monophosphate levels in cultured rat Sertoli cells.
Acta endocrinologica 1993;128(6):568-72.
1993: Krajci P; Taskén K; Kvale D; Brandtzaeg P
Interferon-gamma stimulation of messenger RNA for human secretory component (poly-Ig receptor) depends on continuous intermediate protein synthesis.
Scandinavian journal of immunology 1993;37(2):251-6.
1992: Krajci P; Kvale D; Taskén K; Brandtzaeg P
Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor)
European journal of immunology 1992;22(9):2309-15.
1992: Knutsen H K; Taskén K A; Eskild W; Jahnsen T; Hansson V
Half-lives of different sized mRNAs for the PKA subunit RI alpha are regulated differently in response to inhibition of transcription and translation.
Biochemical and biophysical research communications 1992;184(1):454-60.
1992: Knutsen H K; Taskén K A; Eskild W; Hansson V
Inhibitors of RNA and protein synthesis stabilize messenger RNA for the RII beta subunit of protein kinase A in different cellular compartments.
Biochemical and biophysical research communications 1992;183(2):632-9.
1992: Taskén K A; Knutsen H K; Eikvar L; Taskén K; Eskild W; Jahnsen T; Hansson V
Protein kinase C activation by 12-O-tetradecanoylphorbol 13-acetate modulates messenger ribonucleic acid levels for two of the regulatory subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinases (RII beta and RI alpha) via multiple and distinct mechanisms.
Endocrinology 1992;130(3):1271-80.
1992: Taskén K A; Knutsen H K; Eikvar L; Taskén K; Eskild W; Jahnsen T; Hansson V
Protein kinase C activation by 12-O-tetradecanoylphorbol 13-acetate modulates messenger ribonucleic acid levels for two of the regulatory subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinases (RII beta and RI alpha) via multiple and distinct mechanisms.
Endocrinology 1992;130(3):1271-80.
1991: Knutsen H K; Taskén K A; Eskild W; Jahnsen T; Hansson V
Adenosine 3',5'-monophosphate-dependent stabilization of messenger ribonucleic acids (mRNAs) for protein kinase-A (PKA) subunits in rat Sertoli cells: rapid degradation of mRNAs for PKA subunits is dependent on ongoing RNA and protein synthesis.
Endocrinology 1991;129(5):2496-502.
1991: Solberg R; Taskén K; Keiserud A; Jahnsen T
Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases.
Biochemical and biophysical research communications 1991;176(1):166-72.
1991: Taskén K A; Knutsen H K; Attramadal H; Taskén K; Jahnsen T; Hansson V; Eskild W
Different mechanisms are involved in cAMP-mediated induction of mRNAs for subunits of cAMP-dependent protein kinases.
Molecular endocrinology (Baltimore, Md.) 1991;5(1):21-8.
1991: Taskén K A; Knutsen H K; Attramadal H; Taskén K; Jahnsen T; Hansson V; Eskild W
Different mechanisms are involved in cAMP-mediated induction of mRNAs for subunits of cAMP-dependent protein kinases.
Molecular endocrinology (Baltimore, Md.) 1991;5(1):21-8.
1990: Taskén K; Kvale D; Hansson V; Jahnsen T
Protein kinase C activation selectively increases mRNA levels for one of the regulatory subunits (RI alpha) of cAMP-dependent protein kinases in HT-29 cells.
Biochemical and biophysical research communications 1990;172(2):409-14.
1990: Dissen E; Vaage J T; Taskén K; Jahnsen T; Rolstad B; Fossum S
Alloreactive lymphokine-activated killer cells from athymic nude rats do not express CD3-associated alpha/beta or gamma/delta T cell receptors.
International immunology 1990;2(5):453-60.
1988: Levy F O; Oyen O; Sandberg M; Taskén K; Eskild W; Hansson V; Jahnsen T
Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis.
Molecular endocrinology (Baltimore, Md.) 1988;2(12):1364-73.
1988: Oyen O; Sandberg M; Levy F O; Taskén K; Beebe S; Hansson V; Jahnsen T
Molecular cloning and cell-specific expression of newly discovered subunits of cAMP-dependent protein kinases. Implications for different cellular responses to cAMP.
APMIS. Supplementum 1988;2():238-50.
1987: Sandberg M; Taskén K; Oyen O; Hansson V; Jahnsen T
Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis.
Biochemical and biophysical research communications 1987;149(3):939-45.

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