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Hwee Kee Tay

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Hwee Kee Tay; Alirio J Melendez
FcγRI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells.
Peter Natesan Pushparaj; Hwee Kee Tay
Retraction: VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-α secretion, peritonitis, and systemic inflammation.
Dimity H Ball; Kara S Bell; Michelle L Coates; William Harnett; Justyna Rzepecka; Hwee Kee Tay; Lamyaa Al-Riyami; Margaret M Harnett
Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62.

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All Publications

2013: Hwee Kee Tay; Alirio J Melendez
FcγRI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells.
The Journal of biological chemistry 2013;288(14):10082.
2013: Peter Natesan Pushparaj; Hwee Kee Tay
Retraction: VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-α secretion, peritonitis, and systemic inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):3007.
2013: Dimity H Ball; Kara S Bell; Michelle L Coates; William Harnett; Justyna Rzepecka; Hwee Kee Tay; Lamyaa Al-Riyami; Margaret M Harnett
Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62.
Journal of parasitology research 2013;2013():961268.
2012: Peter Natesan Pushparaj; Hwee Kee Tay; Josef Pfeilschifter; Andrea Huwiler
Retraction: Sphingosine kinase1 is pivotal for Fc"RI-mediated mast cell signaling and functional responses in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(6):3262.
2012: Jingli Zhuo; Yaw Chong Goh; Shing Chuan Hooi; Manikandan Jayapal; Shiuan Koh; Alan Prem Kumar; Yaw-Chyn Lim; Sutherland K Maciver; Manuel Salto-Tellez; Ee Hong Tan; Hwee Kee Tay; Lalchhandami Tochhawng; Benedict Yan; Celestial T Yap
Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade.
PloS one 2012;7(8):e43594.
2011: Padmam Puneet; Mairi A McGrath; Hwee Kee Tay; Lamyaa Al-Riyami; Justyna Rzepecka; Shabbir M Moochhala; Shazib Pervaiz; Margaret M Harnett; William Harnett; Alirio J Melendez
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88.
Nature immunology 2011;12(4):344-51.
2010: Damo Xu; Hui-Rong Jiang; Yubin Li; Peter Natesan Pushparaj; Mariola Kurowska-Stolarska; Bernard P Leung; Rong Mu; Hwee Kee Tay; Andrew N J McKenzie; Iain B McInnes; Alirio J Melendez; Foo Y Liew
IL-33 exacerbates autoantibody-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2620-6.
2009: Peter Natesan Pushparaj; Hwee Kee Tay; Cheng-Chun Wang; Wanjin Hong; Alirio J Melendez
VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1413-8.
2009: Xilei Dai; Manikandan Jayapal; Hwee Kee Tay; Renji Reghunathan; Gen Lin; Chien Tei Too; Yan Ting Lim; Soh Ha Chan; D Michael Kemeny; R Andres Floto; Kenneth G C Smith; Alirio J Melendez; Paul A MacAry
Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcgammaRI versus FcgammaRIIa.
Blood 2009;114(2):318-27.
2009: Peter Natesan Pushparaj; Manikandan Jayapal; Hwee Kee Tay; Shiau Chen H'ng; Srinivasan D Kumar; Josef Pfeilschifter; Andrea Huwiler; Alirio J Melendez
Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):221-7.
2009: Peter Natesan Pushparaj; Hwee Kee Tay; Damo Xu; Nick Pitman; Shiau Chen H'ng; Foo Y Liew; Andrew McKenzie; Alirio J Melendez
The cytokine interleukin-33 mediates anaphylactic shock.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(24):9773-8.
2008: Alirio J Melendez; Hwee Kee Tay
Phagocytosis: a repertoire of receptors and Ca(2+) as a key second messenger.
Bioscience reports 2008;28(5):287-98.
2007: Alirio J Melendez; Margaret M Harnett; Peter Natesan Pushparaj; W S Fred Wong; Hwee Kee Tay; Charles P McSharry; William Harnett
Inhibition of Fc epsilon RI-mediated mast cell responses by ES-62, a product of parasitic filarial nematodes.
Nature medicine 2007;13(11):1375-81.
2006: Manikandan Jayapal; Hwee Kee Tay; Renji Reghunathan; Liang Zhi; Kah Kiong Chow; Mary Rauff; Alirio J Melendez
Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses.
BMC genomics 2006;7():210.
2004: Hwee Kee Tay; Alirio J Melendez
Fcgamma RI-triggered generation of arachidonic acid and eicosanoids requires iPLA2 but not cPLA2 in human monocytic cells.
The Journal of biological chemistry 2004;279(21):22505-13.