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Frederick Taylor

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Chemicals & Drugs

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Post Translational Protein Processing

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Renée I Shapiro; Tatiana Plavina; Brian R Schlain; R Blake Pepinsky; Ellen A Garber; Matthew Jarpe; Paula S Hochman; Nancy G Wehner; Frederique Bard; Ruth Motter; Ted Yednock; Frederick R Taylor
Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4.
Darren P Baker; Frederick R Taylor; R Blake Pepinsky
Purifying the hedgehog protein and its variants.
Frederick R Taylor; Holly Lynn Prentice; Ellen A Garber; Hans A Fajardo; Elena Vasilyeva; R Blake Pepinsky
Suppression of sodium dodecyl sulfate-polyacrylamide gel electrophoresis sample preparation artifacts for analysis of IgG4 half-antibody.

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All Publications

2011: Renée I Shapiro; Tatiana Plavina; Brian R Schlain; R Blake Pepinsky; Ellen A Garber; Matthew Jarpe; Paula S Hochman; Nancy G Wehner; Frederique Bard; Ruth Motter; Ted Yednock; Frederick R Taylor
Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4.
Journal of pharmaceutical and biomedical analysis 2011;55(1):168-75.
2007: Darren P Baker; Frederick R Taylor; R Blake Pepinsky
Purifying the hedgehog protein and its variants.
Methods in molecular biology (Clifton, N.J.) 2007;397():1-22.
2006: Frederick R Taylor; Holly Lynn Prentice; Ellen A Garber; Hans A Fajardo; Elena Vasilyeva; R Blake Pepinsky
Suppression of sodium dodecyl sulfate-polyacrylamide gel electrophoresis sample preparation artifacts for analysis of IgG4 half-antibody.
Analytical biochemistry 2006;353(2):204-8.
2004: Elena Vasilyeva; James Woodard; Frederick R Taylor; Matthias Kretschmer; Hans Fajardo; Yelena Lyubarskaya; Kazumi Kobayashi; Amy Dingley; Rohin Mhatre
Development of a chip-based capillary gel electrophoresis method for quantification of a half-antibody in immunoglobulin G4 samples.
Electrophoresis 2004;25(21-22):3890-6.
2004: Janine L Ferrant; Christopher D Benjamin; Anne H Cutler; Susan L Kalled; Yen-Ming Hsu; Ellen A Garber; Donna M Hess; Renee I Shapiro; Norma S Kenyon; David M Harlan; Allan D Kirk; Linda C Burkly; Frederick R Taylor
The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge.
International immunology 2004;16(11):1583-94.
2004: Lex Nagelkerken; Inge Haspels; Wouter Van Rijs; Bep Blauw; Janine L Ferrant; Donna M Hess; Ellen A Garber; Frederick R Taylor; Linda C Burkly
FcR interactions do not play a major role in inhibition of experimental autoimmune encephalomyelitis by anti-CD154 monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):993-9.
2003: Renee I Shapiro; Dingyi Wen; Melissa Levesque; Xiaoping Hronowski; Alan Gill; Ellen A Garber; Alphonse Galdes; Kathy Strauch; Frederick R Taylor
Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications.
Protein expression and purification 2003;29(2):272-83.
2003: Michael Karpusas; Janine L Ferrant; Paul H Weinreb; Amie Carmillo; Frederick R Taylor; Ellen A Garber
Crystal structure of the alpha1beta1 integrin I domain in complex with an antibody Fab fragment.
Journal of molecular biology 2003;327(5):1031-41.
2003: Nigel A Calcutt; Karen L Allendoerfer; Andrew P Mizisin; Alicia Middlemas; Jason D Freshwater; Monica Burgers; Rigel Ranciato; Jean-Dominique Delcroix; Frederick R Taylor; Renee Shapiro; Kathy Strauch; Henryk Dudek; Thomas Engber; Alphonse Galdes; Lee L Rubin; David R Tomlinson
Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.
The Journal of clinical investigation 2003;111(4):507-14.
2002: Janine L Ferrant; Cheryl A Wilson; Christopher D Benjamin; Donna M Hess; Yen-Ming Hsu; Michael Karpusas; Kenneth H Roux; Frederick R Taylor
Variation in the ordered structure of complexes between CD154 and anti-CD154 monoclonal antibodies.
Molecular immunology 2002;39(1-2):77-84.
2002: R Blake Pepinsky; Renee I Shapiro; Shaoshan Wang; Abhijit Chakraborty; Alan Gill; Doreen J Lepage; Dingyi Wen; Paul Rayhorn; Gerald S B Horan; Frederick R Taylor; Ellen A Garber; Alphonse Galdes; Thomas Engber
Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model.
Journal of pharmaceutical sciences 2002;91(2):371-87.
2001: Frederick R Taylor; Janine L Ferrant; S F Foley; C Zeng; J Sernatinger; R Juffras; R Blake Pepinsky
Biochemical analysis of retroviral structural proteins to identify and quantify retrovirus expressed by an NS0 murine myeloma cell line.
Journal of biotechnology 2001;84(1):33-43.
2001: Roberto Pola; Leona E Ling; Marcy Silver; M J Corbley; Marianne Kearney; R Blake Pepinsky; R Shapiro; Frederick R Taylor; Darren P Baker; Takayuki Asahara; Jeffrey M Isner
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors.
Nature medicine 2001;7(6):706-11.
2001: Frederick R Taylor; Dingyi Wen; Ellen A Garber; A N Carmillo; Darren P Baker; Robert M Arduini; Kevin P Williams; Paul H Weinreb; Paul Rayhorn; Xiaoping Hronowski; Adrian Whitty; Eric S Day; A Boriack-Sjodin; Renee I Shapiro; Alphonse Galdes; R Blake Pepinsky
Enhanced potency of human Sonic hedgehog by hydrophobic modification.
Biochemistry 2001;40(14):4359-71.
2001: Michael Karpusas; J Lucci; Janine L Ferrant; Christopher D Benjamin; Frederick R Taylor; Kathy Strauch; Ellen A Garber; Yen-Ming Hsu
Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody.
Structure (London, England : 1993) 2001;9(4):321-9.
2000: L C Wang; Z Y Liu; Laure Gambardella; A Delacour; R Shapiro; J Yang; Irene Sizing; Paul Rayhorn; Ellen A Garber; Christopher D Benjamin; Kevin P Williams; Frederick R Taylor; Yann Barrandon; L Ling; Linda C Burkly
Regular articles: conditional disruption of hedgehog signaling pathway defines its critical role in hair development and regeneration.
The Journal of investigative dermatology 2000;114(5):901-8.
2000: R Blake Pepinsky; Paul Rayhorn; Eric S Day; A Dergay; Kevin P Williams; Alphonse Galdes; Frederick R Taylor; P A Boriack-Sjodin; Ellen A Garber
Mapping sonic hedgehog-receptor interactions by steric interference.
The Journal of biological chemistry 2000;275(15):10995-1001.
1999: Kevin P Williams; Paul Rayhorn; G Chi-Rosso; Ellen A Garber; Kathy Strauch; G S Horan; Jennifer Ott Reilly; Darren P Baker; Frederick R Taylor; Victor E Koteliansky; R Blake Pepinsky
Functional antagonists of sonic hedgehog reveal the importance of the N terminus for activity.
Journal of cell science 1999;112 ( Pt 23)():4405-14.
1999: Frederick R Taylor; Sarah A Bixler; J I Budman; Dingyi Wen; Michael Karpusas; Sarah T Ryan; G J Jaworski; A Safari-Fard; S Pollard; Adrian Whitty
Induced fit activation mechanism of the exceptionally specific serine protease, complement factor D.
Biochemistry 1999;38(9):2849-59.
1998: R Blake Pepinsky; C Zeng; Dingyi Wen; Paul Rayhorn; Darren P Baker; Kevin P Williams; Sarah A Bixler; Christine Ambrose; Ellen A Garber; Konrad Miatkowski; Frederick R Taylor; E A Wang; Alphonse Galdes
Identification of a palmitic acid-modified form of human Sonic hedgehog.
The Journal of biological chemistry 1998;273(22):14037-45.