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Palmer Taylor

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Torpedo

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Co-Publications
Name
56
Radic, Zoran
24
Camp, Shelley
18
Marchot, Pascale
18
Sine, Steven
17
Tsigelny, Igor
17
Talley, Todd
13
Yaksh, Tony
13
Comoletti, Davide
13
Bourne, Yves
12
Doctor, Bhupendra
12
Hansen, Scott
12
Khan, Imran
10
Li, Ying
9
Kovarik, Zrinka
9
Berman, Harvey

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Publications

TOP 3
Luo Jie; Taylor Palmer; Losen Mario; de Baets Marc H; Shelton G Diane; Lindstrom Jon
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
Rana Brinda K; Wessel Jennifer; Mahboubi Vafa; Rao Fangwen; Haeller Jeannine; Gayen Jiaur R; Eskin Eleazar; Valle Anne M; Das Madhusudan; Mahata Sushil K; Taupenot Laurent; Stridsberg Mats; Talley Todd T; Ziegler Michael G; Smith Douglas W; Schork Nicholas J; O'Connor Daniel T; Taylor Palmer
Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs.
Hibbs Ryan E; Sulzenbacher Gerlind; Shi Jianxin; Talley Todd T; Conrod Sandrine; Kem William R; Taylor Palmer; Marchot Pascale; Bourne Yves
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.

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All Publications

2009: Luo Jie; Taylor Palmer; Losen Mario; de Baets Marc H; Shelton G Diane; Lindstrom Jon
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(44):13898-908.
2009: Rana Brinda K; Wessel Jennifer; Mahboubi Vafa; Rao Fangwen; Haeller Jeannine; Gayen Jiaur R; Eskin Eleazar; Valle Anne M; Das Madhusudan; Mahata Sushil K; Taupenot Laurent; Stridsberg Mats; Talley Todd T; Ziegler Michael G; Smith Douglas W; Schork Nicholas J; O'Connor Daniel T; Taylor Palmer
Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs.
The Journal of pharmacology and experimental therapeutics 2009;331(2):419-28.
2009: Hibbs Ryan E; Sulzenbacher Gerlind; Shi Jianxin; Talley Todd T; Conrod Sandrine; Kem William R; Taylor Palmer; Marchot Pascale; Bourne Yves
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
The EMBO journal 2009;28(19):3040-51.
2009: Tomizawa Motohiro; Talley Todd T; Park John F; Maltby David; Medzihradszky Katalin F; Durkin Kathleen A; Cornejo-Bravo Jose M; Burlingame Alma L; Casida John E; Taylor Palmer
Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling.
Journal of medicinal chemistry 2009;52(12):3735-41.
2009: Dobbertin Alexandre; Hrabovska Anna; Dembele Korami; Camp Shelley; Taylor Palmer; Krejci Eric; Bernard Véronique
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(14):4519-30.
2009: Babakhani Arneh; Talley Todd T; Taylor Palmer; McCammon J A
A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach.
Computational biology and chemistry 2009;33(2):160-70.
2009: Boudinot Eliane; Bernard Véronique; Camp Shelley; Taylor Palmer; Champagnat Jean; Krejci Eric; Foutz Arthur S
Influence of differential expression of acetylcholinesterase in brain and muscle on respiration.
Respiratory physiology & neurobiology 2009;165(1):40-8.
2008: Suckow Arthur T; Comoletti Davide; Waldrop Megan A; Mosedale Merrie; Egodage Sonya; Taylor Palmer; Chessler Steven D
Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion.
Endocrinology 2008;149(12):6006-17.
2008: Radic Zoran; Manetsch Roman; Fournier Didier; Sharpless K Barry; Taylor Palmer
Probing gorge dimensions of cholinesterases by freeze-frame click chemistry.
Chemico-biological interactions 2008;175(1-3):161-5.
2008: De Jaco Antonella; Comoletti Davide; King Charles C; Taylor Palmer
Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism.
Chemico-biological interactions 2008;175(1-3):349-51.
2008: Comoletti Davide; Grishaev Alexander; Whitten Andrew E; Taylor Palmer; Trewhella Jill
Characterization of the solution structure of a neuroligin/beta-neurexin complex.
Chemico-biological interactions 2008;175(1-3):150-5.
2008: Valle A M; Radic Z; Rana B K; Whitfield J B; O'Connor D T; Martin N G; Taylor P
The cholinesterases: analysis by pharmacogenomics in man.
Chemico-biological interactions 2008;175(1-3):343-5.
2008: Figg William D; Chau Cindy H; Okita Richard; Preusch Peter; Tracy Timothy S; McLeod Howard; Reed Michael; Pieper John; Knoell Daren; Miller Ken; Speedie Marilyn; Blouin Robert; Kroboth Patricia; Koda-Kimble Mary Anne; Taylor Palmer; Cohen Jordan; Giacomini Kathy
Pharm. D. pathways to biomedical research: the National Institutes of Health special conference on pharmacy research.
Pharmacotherapy 2008;28(7):821-33.
2008: Talley Todd T; Harel Michal; Hibbs Ryan E; Radic Zoran; Tomizawa Motohiro; Casida John E; Taylor Palmer
Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7606-11.
2008: Camp Shelley; De Jaco Antonella; Zhang Limin; Marquez Michael; De la Torre Brian; Taylor Palmer
Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(10):2459-70.
2008: Wang Hai-Long; Cheng Xiaolin; Taylor Palmer; McCammon J Andrew; Sine Steven M
Control of cation permeation through the nicotinic receptor channel.
PLoS computational biology 2008;4(2):e41.
2008: Tomizawa Motohiro; Maltby David; Talley Todd T; Durkin Kathleen A; Medzihradszky Katalin F; Burlingame Alma L; Taylor Palmer; Casida John E
Atypical nicotinic agonist bound conformations conferring subtype selectivity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1728-32.
2007: Fabrichny Igor P; Leone Philippe; Sulzenbacher Gerlind; Comoletti Davide; Miller Meghan T; Taylor Palmer; Bourne Yves; Marchot Pascale
Structural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesion.
Neuron 2007;56(6):979-91.
2007: Taylor Palmer; Talley Todd T; Radic' Zoran; Hansen Scott B; Hibbs Ryan E; Shi Jian
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes.
Biochemical pharmacology 2007;74(8):1164-71.
2007: Taylor Palmer; Reiner Elsa; Kovarik Zrinka; Radic Zoran
Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors.
Arhiv za higijenu rada i toksikologiju 2007;58(3):339-45.
2007: Tomizawa Motohiro; Maltby David; Medzihradszky Katalin F; Zhang Nanjing; Durkin Kathleen A; Presley Jack; Talley Todd T; Taylor Palmer; Burlingame Alma L; Casida John E
Defining nicotinic agonist binding surfaces through photoaffinity labeling.
Biochemistry 2007;46(30):8798-806.
2007: Comoletti Davide; Grishaev Alexander; Whitten Andrew E; Tsigelny Igor; Taylor Palmer; Trewhella Jill
Synaptic arrangement of the neuroligin/beta-neurexin complex revealed by X-ray and neutron scattering.
Structure (London, England : 1993) 2007;15(6):693-705.
2007: Hansen Scott B; Taylor Palmer
Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
Journal of molecular biology 2007;369(4):895-901.
2007: Tomizawa Motohiro; Talley Todd T; Maltby David; Durkin Kathleen A; Medzihradszky Katalin F; Burlingame Alma L; Taylor Palmer; Casida John E
Mapping the elusive neonicotinoid binding site.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):9075-80.
2007: Taylor Palmer; Kovarik Zrinka; Reiner Elsa; Radic Zoran
Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure.
Toxicology 2007;233(1-3):70-8.
2007: Kovarik Zrinka; Radic Zoran; Berman Harvey A; Taylor Palmer
Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates.
Toxicology 2007;233(1-3):79-84.
2007: Kang Tse Siang; Radic Zoran; Talley Todd T; Jois Seetharama D S; Taylor Palmer; Kini R Manjunatha
Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins.
Biochemistry 2007;46(11):3338-55.
2006: Hibbs Ryan E; Radic Zoran; Taylor Palmer; Johnson David A
Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein.
The Journal of biological chemistry 2006;281(51):39708-18.
2006: Comoletti Davide; Flynn Robyn E; Boucard Antony A; Demeler Borries; Schirf Virgil; Shi Jianxin; Jennings Lori L; Newlin Helen R; Südhof Thomas C; Taylor Palmer
Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins.
Biochemistry 2006;45(42):12816-27.
2006: Gao Fan; Mer Georges; Tonelli Marco; Hansen Scott B; Burghardt Thomas P; Taylor Palmer; Sine Steven M
Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop.
Molecular pharmacology 2006;70(4):1230-5.
2006: Bourne Yves; Radic Zoran; Sulzenbacher Gerlind; Kim Esther; Taylor Palmer; Marchot Pascale
Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding.
The Journal of biological chemistry 2006;281(39):29256-67.
2006: Talley Todd T; Olivera Baldomero M; Han Kyou-Hoon; Christensen Sean B; Dowell Cheryl; Tsigelny Igor; Ho Kwok-Yiu; Taylor Palmer; McIntosh J Michael
Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors.
The Journal of biological chemistry 2006;281(34):24678-86.
2006: Talley Todd T; Yalda Samar; Ho Kwok-Yiu; Tor Yitzhak; Soti Ferene S; Kem William R; Taylor Palmer
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions.
Biochemistry 2006;45(29):8894-902.
2006: Valle Anne; O'Connor Daniel T; Taylor Palmer; Zhu Gu; Montgomery Grant W; Slagboom P Eline; Martin Nicholas G; Whitfield John B
Butyrylcholinesterase: association with the metabolic syndrome and identification of 2 gene loci affecting activity.
Clinical chemistry 2006;52(6):1014-20.
2006: Bui Jennifer M; Radic Zoran; Taylor Palmer; McCammon J Andrew
Conformational transitions in protein-protein association: binding of fasciculin-2 to acetylcholinesterase.
Biophysical journal 2006;90(9):3280-7.
2006: Kovarik Zrinka; Ciban Nikolina; Radic Zoran; Simeon-Rudolf Vera; Taylor Palmer
Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP.
Biochemical and biophysical research communications 2006;342(3):973-8.
2006: Shi Jianxin; Koeppe Julia R; Komives Elizabeth A; Taylor Palmer
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry.
The Journal of biological chemistry 2006;281(17):12170-7.
2006: De Jaco Antonella; Comoletti Davide; Kovarik Zrinka; Gaietta Guido; Radic Zoran; Lockridge Oksana; Ellisman Mark H; Taylor Palmer
A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family.
The Journal of biological chemistry 2006;281(14):9667-76.
2006: Bourne Yves; Hansen Scott B; Sulzenbacher Gerlind; Talley Todd T; Huxford Tom; Taylor Palmer; Marchot Pascale
Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.
Journal of molecular neuroscience : MN 2006;30(1-2):103-4.
2006: Hansen Scott B; Sulzenbacher Gerlind; Huxford Tom; Marchot Pascale; Bourne Yves; Taylor Palmer
Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica.
Journal of molecular neuroscience : MN 2006;30(1-2):101-2.
2006: Girard Emmanuelle; Bernard Véronique; Camp Shelley; Taylor Palmer; Krejci Eric; Molgó Jordi
Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase.
Journal of molecular neuroscience : MN 2006;30(1-2):99-100.
2006: Hibbs Ryan E; Johnson David A; Shi Jianxin; Taylor Palmer
Structural dynamics of the acetylcholine binding protein: hydrodynamic and fluorescence anisotropy decay analyses.
Journal of molecular neuroscience : MN 2006;30(1-2):73-4.
2005: Pezzementi Leo; Shi Jianxin; Johnson David A; Radic Zoran; Boyd Aileen; Taylor Palmer
Ligand-induced conformational changes in residues flanking the active site gorge of acetylcholinesterase.
Chemico-biological interactions 2005;157-158():413-4.
2005: Luo Chunyuan; Dawson Maureen; Chambers Carolyn; Chilukuri Nageswararao; Radic Zoran; Taylor Palmer; Doctor Bhupendra P; Saxena Ashima
Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases.
Chemico-biological interactions 2005;157-158():393-4.
2005: Kovarik Zrinka; Radic Zoran; Simeon-Rudolf Vera; Reiner Elsa; Taylor Palmer
Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates.
Chemico-biological interactions 2005;157-158():388-90.
2005: De Jaco Antonella; Camp Shelley; Taylor Palmer
Influence of the 5' intron in the control of acetylcholinesterase gene expression during myogenesis.
Chemico-biological interactions 2005;157-158():372-3.
2005: De Jaco Antonella; Kovarik Zrinka; Comoletti Davide; Jennings Lori L; Gaietta Guido; Ellisman Mark H; Taylor Palmer
A single mutation near the C-terminus in alpha/beta hydrolase fold protein family causes a defect in protein processing.
Chemico-biological interactions 2005;157-158():371-2.
2005: Hibbs Ryan E; Johnson David A; Shi Jianxin; Hansen Scott B; Taylor Palmer
Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: hydrodynamic and fluorescence anisotropy decay analyses.
Biochemistry 2005;44(50):16602-11.
2005: Radic Zoran; Manetsch Roman; Krasinski Antoni; Raushel Jessica; Yamauchi John; Garcia Cindy; Kolb Hartmuth; Sharpless K Barry; Taylor Palmer
Molecular basis of interactions of cholinesterases with tight binding inhibitors.
Chemico-biological interactions 2005;157-158():133-41.
2005: Camp Shelley; Zhang Limin; Marquez Michael; de la Torre Brian; Long Jeffery M; Bucht Goran; Taylor Palmer
Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion.
Chemico-biological interactions 2005;157-158():79-86.
2005: Bourne Yves; Radic Zoran; Kolb Hartmuth C; Sharpless K Barry; Taylor Palmer; Marchot Pascale
Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE.
Chemico-biological interactions 2005;157-158():159-65.
2005: Boucard Antony A; Chubykin Alexander A; Comoletti Davide; Taylor Palmer; Südhof Thomas C
A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins.
Neuron 2005;48(2):229-36.
2005: Hansen Scott B; Sulzenbacher Gerlind; Huxford Tom; Marchot Pascale; Taylor Palmer; Bourne Yves
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations.
The EMBO journal 2005;24(20):3635-46.
2005: Chubykin Alexander A; Liu Xinran; Comoletti Davide; Tsigelny Igor; Taylor Palmer; Südhof Thomas C
Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism.
The Journal of biological chemistry 2005;280(23):22365-74.
2005: Krasinski Antoni; Radic Zoran; Manetsch Roman; Raushel Jessica; Taylor Palmer; Sharpless K Barry; Kolb Hartmuth C
In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors.
Journal of the American Chemical Society 2005;127(18):6686-92.
2005: Bourne Yves; Talley Todd T; Hansen Scott B; Taylor Palmer; Marchot Pascale
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.
The EMBO journal 2005;24(8):1512-22.
2005: Henchman Richard H; Wang Hai-Long; Sine Steven M; Taylor Palmer; McCammon J Andrew
Ligand-induced conformational change in the alpha7 nicotinic receptor ligand binding domain.
Biophysical journal 2005;88(4):2564-76.
2005: Zhang Deqiang; Suen Jason; Zhang Yongjie; Song Yuhua; Radic Zoran; Taylor Palmer; Holst Michael J; Bajaj Chandrajit; Baker Nathan A; McCammon J Andrew
Tetrameric mouse acetylcholinesterase: continuum diffusion rate calculations by solving the steady-state Smoluchowski equation using finite element methods.
Biophysical journal 2005;88(3):1659-65.
2005: Gao Fan; Bren Nina; Burghardt Thomas P; Hansen Scott; Henchman Richard H; Taylor Palmer; McCammon J Andrew; Sine Steven M
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence.
The Journal of biological chemistry 2005;280(9):8443-51.
2004: Manetsch Roman; Krasinski Antoni; Radic Zoran; Raushel Jessica; Taylor Palmer; Sharpless K Barry; Kolb Hartmuth C
In situ click chemistry: enzyme inhibitors made to their own specifications.
Journal of the American Chemical Society 2004;126(40):12809-18.
2004: Khan Imran M; Wennerholm Michelle; Singletary Erin; Polston Kimberley; Zhang Limin; Deerinck Tom; Yaksh Tony L; Taylor Palmer
Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord.
Journal of neurocytology 2004;33(5):543-56.
2004: Bouzat Cecilia; Gumilar Fernanda; Spitzmaul Guillermo; Wang Hai-Long; Rayes Diego; Hansen Scott B; Taylor Palmer; Sine Steven M
Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.
Nature 2004;430(7002):896-900.
2004: Hibbs Ryan E; Talley Todd T; Taylor Palmer
Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein.
The Journal of biological chemistry 2004;279(27):28483-91.
2004: Boyd Aileen E; Dunlop Cristina S; Wong Lilly; Radic Zoran; Taylor Palmer; Johnson David A
Nanosecond dynamics of acetylcholinesterase near the active center gorge.
The Journal of biological chemistry 2004;279(25):26612-8.
2004: Hansen Scott B; Talley Todd T; Radic Zoran; Taylor Palmer
Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica.
The Journal of biological chemistry 2004;279(23):24197-202.
2004: Comoletti Davide; De Jaco Antonella; Jennings Lori L; Flynn Robyn E; Gaietta Guido; Tsigelny Igor; Ellisman Mark H; Taylor Palmer
The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(20):4889-93.
2004: Taylor Palmer; Hansen Scott B; Talley Todd T; Hibbs Ryan E; Radic Zoran
Contemporary paradigms for cholinergic ligand design guided by biological structure.
Bioorganic & medicinal chemistry letters 2004;14(8):1875-7.
2004: Kovarik Zrinka; Radic Zoran; Berman Harvey A; Simeon-Rudolf Vera; Reiner Elsa; Taylor Palmer
Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates.
Biochemistry 2004;43(11):3222-9.
2004: Hoffman Ross C; Jennings Lori L; Tsigelny Igor; Comoletti Davide; Flynn Robyn E; Sudhof Thomas C; Taylor Palmer
Structural characterization of recombinant soluble rat neuroligin 1: mapping of secondary structure and glycosylation by mass spectrometry.
Biochemistry 2004;43(6):1496-506.
2004: Bourne Yves; Kolb Hartmuth C; Radic Zoran; Sharpless K Barry; Taylor Palmer; Marchot Pascale
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(6):1449-54.
2003: Khan Imran; Osaka Hitoshi; Stanislaus Shanaka; Calvo Rosa M; Deerinck Tom; Yaksh Tony L; Taylor Palmer
Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways.
The Journal of comparative neurology 2003;467(1):44-59.
2003: Comoletti Davide; Flynn Robyn; Jennings Lori L; Chubykin Alexander; Matsumura Takehito; Hasegawa Hana; Südhof Thomas C; Taylor Palmer
Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta.
The Journal of biological chemistry 2003;278(50):50497-505.
2003: Saxena Ashima; Fedorko James M; Vinayaka C R; Medhekar Rohit; Radic Zoran; Taylor Palmer; Lockridge Oksana; Doctor Bhupendra P
Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
European journal of biochemistry / FEBS 2003;270(22):4447-58.
2003: Henchman Richard H; Wang Hai-Long; Sine Steven M; Taylor Palmer; McCammon J Andrew
Asymmetric structural motions of the homomeric alpha7 nicotinic receptor ligand binding domain revealed by molecular dynamics simulation.
Biophysical journal 2003;85(5):3007-18.
2003: George Kathleen M; Schule Travis; Sandoval Lisa E; Jennings Lori L; Taylor Palmer; Thompson Charles M
Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate.
The Journal of biological chemistry 2003;278(46):45512-8.
2003: Jennings Lori L; Malecki Michael; Komives Elizabeth A; Taylor Palmer
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry.
Biochemistry 2003;42(37):11083-91.
2003: Luo Chunyuan; Leader Haim; Radic Zoran; Maxwell Donald M; Taylor Palmer; Doctor Bhupendra P; Saxena Ashima
Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase.
Biochemical pharmacology 2003;66(3):387-92.
2003: Shi Jianxin; Tai Kaihsu; McCammon J Andrew; Taylor Palmer; Johnson David A
Nanosecond dynamics of the mouse acetylcholinesterase cys69-cys96 omega loop.
The Journal of biological chemistry 2003;278(33):30905-11.
2003: Kovarik Zrinka; Radic Zoran; Berman Harvey A; Simeon-Rudolf Vera; Reiner Elsa; Taylor Palmer
Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.
The Biochemical journal 2003;373(Pt 1):33-40.
2003: Gao Fan; Bern Nina; Little Alicia; Wang Hai-Long; Hansen Scott B; Talley Todd T; Taylor Palmer; Sine Steven M
Curariform antagonists bind in different orientations to acetylcholine-binding protein.
The Journal of biological chemistry 2003;278(25):23020-6.
2003: Taylor Palmer
Keeping the identity of pharmacology strong for the future.
Molecular interventions 2003;3(1):6-10.
2003: Bourne Yves; Taylor Palmer; Radic Zoran; Marchot Pascale
Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
The EMBO journal 2003;22(1):1-12.
2002: Hansen Scott B; Radic' Zoran; Talley Todd T; Molles Brian E; Deerinck Tom; Tsigelny Igor; Taylor Palmer
Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein.
The Journal of biological chemistry 2002;277(44):41299-302.
2002: Shi Jianxin; Radic' Zoran; Taylor Palmer
Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase.
The Journal of biological chemistry 2002;277(45):43301-8.
2002: Khan Imran M; Singletary Erin; Alemayehu Adamu; Stanislaus Shanaka; Printz Morton P; Yaksh Tony L; Taylor Palmer
Nicotinic receptor gene cluster on rat chromosome 8 in nociceptive and blood pressure hyperresponsiveness.
Physiological genomics 2002;11(2):65-72.
2002: Molles Brian E; Tsigelny Igor; Nguyen Phuong D; Gao Sarah X; Sine Steven M; Taylor Palmer
Residues in the epsilon subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the alpha-epsilon subunit interface site.
Biochemistry 2002;41(25):7895-906.
2002: Satoh Tetsuo; Taylor Palmer; Bosron William F; Sanghani Sonal P; Hosokawa Masakiyo; La Du Bert N
Current progress on esterases: from molecular structure to function.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(5):488-93.
2002: Lewis Warren G; Green Luke G; Grynszpan Flavio; Radic Zoran; Carlier Paul R; Taylor Palmer; Finn M G; Sharpless K Barry
Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks.
Angewandte Chemie (International ed. in English) 2002;41(6):1053-7.
2002: Molles Brian E; Rezai Parastoo; Kline Eric F; McArdle Joseph J; Sine Steven M; Taylor Palmer
Identification of residues at the alpha and epsilon subunit interfaces mediating species selectivity of Waglerin-1 for nicotinic acetylcholine receptors.
The Journal of biological chemistry 2002;277(7):5433-40.
2001: Radic Z; Taylor P
Peripheral site ligands accelerate inhibition of acetylcholinesterase by neutral organophosphates.
Journal of applied toxicology : JAT 2001;21 Suppl 1():S13-4.
2001: Shi J; Boyd A E; Radic Z; Taylor P
Reversibly bound and covalently attached ligands induce conformational changes in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase.
The Journal of biological chemistry 2001;276(45):42196-204.
2001: Khan I M; Stanislaus S; Zhang L; Vaughn D; Printz M P; Yaksh T L; Taylor P
Spinal nicotinic receptor activity in a genetic model of hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) 2001;23(7):555-68.
2001: Keller S H; Lindstrom J; Ellisman M; Taylor P
Adjacent basic amino acid residues recognized by the COP I complex and ubiquitination govern endoplasmic reticulum to cell surface trafficking of the nicotinic acetylcholine receptor alpha-Subunit.
The Journal of biological chemistry 2001;276(21):18384-91.
2001: Khan I M; Stanislaus S; Zhang L; Taylor P; Yaksh T L
A-85380 and epibatidine each interact with disparate spinal nicotinic receptor subtypes to achieve analgesia and nociception.
The Journal of pharmacology and experimental therapeutics 2001;297(1):230-9.
2001: Radic Z; Taylor P
Interaction kinetics of reversible inhibitors and substrates with acetylcholinesterase and its fasciculin 2 complex.
The Journal of biological chemistry 2001;276(7):4622-33.
2000: Malany S; Osaka H; Sine S M; Taylor P
Orientation of alpha-neurotoxin at the subunit interfaces of the nicotinic acetylcholine receptor.
Biochemistry 2000;39(50):15388-98.
2000: Saltmarsh J R; Boyd A E; Rodriguez O P; Radic Z; Taylor P; Thompson C M
Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase.
Bioorganic & medicinal chemistry letters 2000;10(14):1523-6.
2000: Boyd A E; Marnett A B; Wong L; Taylor P
Probing the active center gorge of acetylcholinesterase by fluorophores linked to substituted cysteines.
The Journal of biological chemistry 2000;275(29):22401-8.
2000: Wong L; Radic Z; Brüggemann R J; Hosea N; Berman H A; Taylor P
Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis.
Biochemistry 2000;39(19):5750-7.
2000: Osaka H; Malany S; Molles B E; Sine S M; Taylor P
Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 2000;275(8):5478-84.
2000: Tsigelny I; Shindyalov I N; Bourne P E; Südhof T C; Taylor P
Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations.
Protein science : a publication of the Protein Society 2000;9(1):180-5.
2000: Taylor P; Malanz S; Molles B E; Osaka H; Tsigelny I
Subunit interface selective toxins as probes of nicotinic acetylcholine receptor structure.
Pflügers Archiv : European journal of physiology 2000;440(5 Suppl):R115-7.
1999: Luo Z D; Wang Y; Werlen G; Camp S; Chien K R; Taylor P
Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation.
Molecular pharmacology 1999;56(5):886-94.
1999: Luo C; Saxena A; Smith M; Garcia G; Radic Z; Taylor P; Doctor B P
Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium.
Biochemistry 1999;38(31):9937-47.
1999: Luo C; Saxena A; Ashani Y; Leader H; Radic Z; Taylor P; Doctor B P
Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime.
Chemico-biological interactions 1999;119-120():129-35.
1999: Radic Z; Taylor P
The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases.
Chemico-biological interactions 1999;119-120():111-7.
1999: Taylor P; Wong L; Radic Z; Tsigelny I; Brüggemann R; Hosea N A; Berman H A
Analysis of cholinesterase inactivation and reactivation by systematic structural modification and enantiomeric selectivity.
Chemico-biological interactions 1999;119-120():3-15.
1999: Osaka H; Malany S; Kanter J R; Sine S M; Taylor P
Subunit interface selectivity of the alpha-neurotoxins for the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1999;274(14):9581-6.
1999: Keller S H; Taylor P
Determinants responsible for assembly of the nicotinic acetylcholine receptor.
The Journal of general physiology 1999;113(2):171-6.
1998: Khan I M; Buerkle H; Taylor P; Yaksh T L
Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists.
Neuropharmacology 1998;37(12):1515-25.
1998: Marchot P; Bourne Y; Prowse C N; Bougis P E; Taylor P
Inhibition of mouse acetylcholinesterase by fasciculin: crystal structure of the complex and mutagenesis of fasciculin.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1613-22.
1998: Luo Z D; Camp S; Mutero A; Taylor P
Splicing of 5' introns dictates alternative splice selection of acetylcholinesterase pre-mRNA and specific expression during myogenesis.
The Journal of biological chemistry 1998;273(43):28486-95.
1998: Keller S H; Lindstrom J; Taylor P
Inhibition of glucose trimming with castanospermine reduces calnexin association and promotes proteasome degradation of the alpha-subunit of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1998;273(27):17064-72.
1998: Osaka H; Sugiyama N; Taylor P
Distinctions in agonist and antagonist specificity conferred by anionic residues of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1998;273(21):12758-65.
1998: Ackermann E J; Ang E T; Kanter J R; Tsigelny I; Taylor P
Identification of pairwise interactions in the alpha-neurotoxin-nicotinic acetylcholine receptor complex through double mutant cycles.
The Journal of biological chemistry 1998;273(18):10958-64.
1998: Taylor P; Osaka H; Molles B E; Sugiyama N; Marchot P; Ackermann E J; Malany S; McArdle J J; Sine S M; Tsigelny I
Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure.
Journal of physiology, Paris 1998;92(2):79-83.
1998: Sugiyama N; Marchot P; Kawanishi C; Osaka H; Molles B; Sine S M; Taylor P
Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to alpha-conotoxin M1 binding.
Molecular pharmacology 1998;53(4):787-94.
1997: Taylor P
Metrifonate. A viewpoint.
Drugs & aging 1997;11(6):497.
1997: Ackermann E J; Taylor P
Nonidentity of the alpha-neurotoxin binding sites on the nicotinic acetylcholine receptor revealed by modification in alpha-neurotoxin and receptor structures.
Biochemistry 1997;36(42):12836-44.
1997: Saxena A; Maxwell D M; Quinn D M; Radic Z; Taylor P; Doctor B P
Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning.
Biochemical pharmacology 1997;54(2):269-74.
1997: Taylor P; Ross E M; Sternweis P C; Neubig R R; McCammon J A
Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997).
Molecular pharmacology 1997;52(1):1-5.
1997: Tsigelny I; Sugiyama N; Sine S M; Taylor P
A model of the nicotinic receptor extracellular domain based on sequence identity and residue location.
Biophysical journal 1997;73(1):52-66.
1997: Khan I M; Yaksh T L; Taylor P
Epibatidine binding sites and activity in the spinal cord.
Brain research 1997;753(2):269-82.
1997: Marchot P; Prowse C N; Kanter J; Camp S; Ackermann E J; Radic Z; Bougis P E; Taylor P
Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom.
The Journal of biological chemistry 1997;272(6):3502-10.
1997: Taylor P; Hosea N A; Tsigelny I; Radic Z; Berman H A
Determining ligand orientation and transphosphonylation mechanisms on acetylcholinesterase by Rp, Sp enantiomer selectivity and site-specific mutagenesis.
Enantiomer 1997;2(3-4):249-60.
1996: Khan I M; Youngblood K L; Printz M P; Yaksh T L; Taylor P
Spinal nicotinic receptor expression in spontaneously hypertensive rats.
Hypertension 1996;28(6):1093-9.
1996: Sugiyama N; Boyd A E; Taylor P
Anionic residue in the alpha-subunit of the nicotinic acetylcholine receptor contributing to subunit assembly and ligand binding.
The Journal of biological chemistry 1996;271(43):26575-81.
1996: Keller S H; Lindstrom J; Taylor P
Involvement of the chaperone protein calnexin and the acetylcholine receptor beta-subunit in the assembly and cell surface expression of the receptor.
The Journal of biological chemistry 1996;271(37):22871-7.
1996: Hosea N A; Radic Z; Tsigelny I; Berman H A; Quinn D M; Taylor P
Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates.
Biochemistry 1996;35(33):10995-1004.
1996: Khan I M; Marsala M; Printz M P; Taylor P; Yaksh T L
Intrathecal nicotinic agonist-elicited release of excitatory amino acids as measured by in vivo spinal microdialysis in rats.
The Journal of pharmacology and experimental therapeutics 1996;278(1):97-106.
1996: Luo Z D; Pincon-Raymond M; Taylor P
Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel.
Journal of neurochemistry 1996;67(1):111-8.
1996: Marchot P; Ravelli R B; Raves M L; Bourne Y; Vellom D C; Kanter J; Camp S; Sussman J L; Taylor P
Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin.
Protein science : a publication of the Protein Society 1996;5(4):672-9.
1996: Coleman B A; Taylor P
Regulation of acetylcholinesterase expression during neuronal differentiation.
The Journal of biological chemistry 1996;271(8):4410-6.
1995: Taylor P; Radic Z; Hosea N A; Camp S; Marchot P; Berman H A
Structural bases for the specificity of cholinesterase catalysis and inhibition.
Toxicology letters 1995;82-83():453-8.
1995: Bourne Y; Taylor P; Marchot P
Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex.
Cell 1995;83(3):503-12.
1995: Getman D K; Mutero A; Inoue K; Taylor P
Transcription factor repression and activation of the human acetylcholinesterase gene.
The Journal of biological chemistry 1995;270(40):23511-9.
1995: Radic Z; Quinn D M; Vellom D C; Camp S; Taylor P
Allosteric control of acetylcholinesterase catalysis by fasciculin.
The Journal of biological chemistry 1995;270(35):20391-9.
1995: Hosea N A; Berman H A; Taylor P
Specificity and orientation of trigonal carboxyl esters and tetrahedral alkylphosphonyl esters in cholinesterases.
Biochemistry 1995;34(36):11528-36.
1995: Sine S M; Kreienkamp H J; Bren N; Maeda R; Taylor P
Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity.
Neuron 1995;15(1):205-11.
1995: van den Born H K; Radic Z; Marchot P; Taylor P; Tsigelny I
Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase.
Protein science : a publication of the Protein Society 1995;4(4):703-15.
1995: Ashani Y; Radic Z; Tsigelny I; Vellom D C; Pickering N A; Quinn D M; Doctor B P; Taylor P
Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes.
The Journal of biological chemistry 1995;270(11):6370-80.
1995: Kreienkamp H J; Maeda R K; Sine S M; Taylor P
Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor.
Neuron 1995;14(3):635-44.
1995: Keller S H; Kreienkamp H J; Kawanishi C; Taylor P
Molecular determinants conferring alpha-toxin resistance in recombinant DNA-derived acetylcholine receptors.
The Journal of biological chemistry 1995;270(8):4165-71.
1995: Mutero A; Camp S; Taylor P
Promoter elements of the mouse acetylcholinesterase gene. Transcriptional regulation during muscle differentiation.
The Journal of biological chemistry 1995;270(4):1866-72.
1995: Camp S; Bon S; Li Y; Getman D K; Engel A G; Massoulié J; Taylor P
Patients with congenital myasthenia associated with end-plate acetylcholinesterase deficiency show normal sequence, mRNA splicing, and assembly of catalytic subunits.
The Journal of clinical investigation 1995;95(1):333-40.
1994: Khan I M; Taylor P; Yaksh T L
Stimulatory pathways and sites of action of intrathecally administered nicotinic agents.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1550-7.
1994: Luo Z; Fuentes M E; Taylor P
Regulation of acetylcholinesterase mRNA stability by calcium during differentiation from myoblasts to myotubes.
The Journal of biological chemistry 1994;269(44):27216-23.
1994: Khan I M; Printz M P; Yaksh T L; Taylor P
Augmented responses to intrathecal nicotinic agonists in spontaneous hypertension.
Hypertension 1994;24(5):611-9.
1994: Saxena A; Qian N; Kovach I M; Kozikowski A P; Pang Y P; Vellom D C; Radic Z; Quinn D; Taylor P; Doctor B P
Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases.
Protein science : a publication of the Protein Society 1994;3(10):1770-8.
1994: Taylor P; Radic Z; Kreienkamp H J; Maeda R; Luo Z; Fuentes M E; Vellom D; Pickering N
Expression and ligand specificity of acetylcholinesterase and the nicotinic receptor: a tale of two cholinergic sites.
Biochemical Society transactions 1994;22(3):740-5.
1994: Khan I M; Yaksh T L; Taylor P
Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine.
The Journal of pharmacology and experimental therapeutics 1994;270(1):159-66.
1994: Khan I M; Taylor P; Yaksh T L
Cardiovascular and behavioral responses to nicotinic agents administered intrathecally.
The Journal of pharmacology and experimental therapeutics 1994;270(1):150-8.
1994: Radic Z; Duran R; Vellom D C; Li Y; Cervenansky C; Taylor P
Site of fasciculin interaction with acetylcholinesterase.
The Journal of biological chemistry 1994;269(15):11233-9.
1994: Sine S M; Quiram P; Papanikolaou F; Kreienkamp H J; Taylor P
Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists.
The Journal of biological chemistry 1994;269(12):8808-16.
1994: Rothman A; Wolner B; Button D; Taylor P
Immediate-early gene expression in response to hypertrophic and proliferative stimuli in pulmonary arterial smooth muscle cells.
The Journal of biological chemistry 1994;269(9):6399-404.
1994: Kreienkamp H J; Sine S M; Maeda R K; Taylor P
Glycosylation sites selectively interfere with alpha-toxin binding to the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1994;269(11):8108-14.
1994: Button D; Rothman A; Bongiorno C; Kupperman E; Wolner B; Taylor P
Agonist-selective regulation of polyphosphoinositide metabolism in pulmonary artery smooth muscle cells.
The Journal of biological chemistry 1994;269(9):6390-8.
1994: Taylor P; Radic Z
The cholinesterases: from genes to proteins.
Annual review of pharmacology and toxicology 1994;34():281-320.
1993: Wasserman L; Doctor B P; Gentry M K; Taylor P
Epitope mapping of form-specific and nonspecific antibodies to acetylcholinesterase.
Journal of neurochemistry 1993;61(6):2124-32.
1993: Radic Z; Pickering N A; Vellom D C; Camp S; Taylor P
Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors.
Biochemistry 1993;32(45):12074-84.
1993: Saxena A; Doctor B P; Maxwell D M; Lenz D E; Radic Z; Taylor P
The role of glutamate-199 in the aging of cholinesterase.
Biochemical and biophysical research communications 1993;197(1):343-9.
1993: Taylor P; Li Y; Camp S; Rachinsky T L; Ekström T; Getman D; Fuentes M E; Vellom D C; Radic Z
Structure and regulation of expression of the acetylcholinesterase gene.
Chemico-biological interactions 1993;87(1-3):199-207.
1993: Fuentes M E; Taylor P
Control of acetylcholinesterase gene expression during myogenesis.
Neuron 1993;10(4):679-87.
1993: Li Y; Camp S; Taylor P
Tissue-specific expression and alternative mRNA processing of the mammalian acetylcholinesterase gene.
The Journal of biological chemistry 1993;268(8):5790-7.
1993: Li Y; Camp S; Rachinsky T L; Bongiorno C; Taylor P
Promoter elements and transcriptional control of the mouse acetylcholinesterase gene.
The Journal of biological chemistry 1993;268(5):3563-72.
1993: Ekström T J; Klump W M; Getman D; Karin M; Taylor P
Promoter elements and transcriptional regulation of the acetylcholinesterase gene.
DNA and cell biology 1993;12(1):63-72.
1993: Vellom D C; Radic Z; Li Y; Pickering N A; Camp S; Taylor P
Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity.
Biochemistry 1993;32(1):12-7.
1992: Rachinsky T L; Crenshaw E B; Taylor P
Assignment of the gene for acetylcholinesterase to distal mouse chromosome 5.
Genomics 1992;14(2):511-4.
1992: Radic Z; Gibney G; Kawamoto S; MacPhee-Quigley K; Bongiorno C; Taylor P
Expression of recombinant acetylcholinesterase in a baculovirus system: kinetic properties of glutamate 199 mutants.
Biochemistry 1992;31(40):9760-7.
1992: Getman D K; Eubanks J H; Camp S; Evans G A; Taylor P
The human gene encoding acetylcholinesterase is located on the long arm of chromosome 7.
American journal of human genetics 1992;51(1):170-7.
1991: Li Y; Camp S; Rachinsky T L; Getman D; Taylor P
Gene structure of mammalian acetylcholinesterase. Alternative exons dictate tissue-specific expression.
The Journal of biological chemistry 1991;266(34):23083-90.
1991: Abramson S N; Trischman J A; Tapiolas D M; Harold E E; Fenical W; Taylor P
Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists.
Journal of medicinal chemistry 1991;34(6):1798-804.
1991: Taylor P
The cholinesterases.
The Journal of biological chemistry 1991;266(7):4025-8.
1991: Radic Z; Reiner E; Taylor P
Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives.
Molecular pharmacology 1991;39(1):98-104.
1991: Taylor P; Abramson S N; Johnson D A; Valenzuela C F; Herz J
Distinctions in ligand binding sites on the nicotinic acetylcholine receptor.
Annals of the New York Academy of Sciences 1991;625():568-87.
1990: Gibney G; Camp S; Dionne M; MacPhee-Quigley K; Taylor P
Mutagenesis of essential functional residues in acetylcholinesterase.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7546-50.
1990: Rachinsky T L; Camp S; Li Y; Ekström T J; Newton M; Taylor P
Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species.
Neuron 1990;5(3):317-27.
1990: Ogert R A; Gentry M K; Richardson E C; Deal C D; Abramson S N; Alving C R; Taylor P; Doctor B P
Studies on the topography of the catalytic site of acetylcholinesterase using polyclonal and monoclonal antibodies.
Journal of neurochemistry 1990;55(3):756-63.
1990: Gibney G; Taylor P
Biosynthesis of Torpedo acetylcholinesterase in mammalian cells. Functional expression and mutagenesis of the glycophospholipid-anchored form.
The Journal of biological chemistry 1990;265(21):12576-83.
1990: Maulet Y; Camp S; Gibney G; Rachinsky T L; Ekström T J; Taylor P
Single gene encodes glycophospholipid-anchored and asymmetric acetylcholinesterase forms: alternative coding exons contain inverted repeat sequences.
Neuron 1990;4(2):289-301.
1989: Abramson S N; Radic Z; Manker D; Faulkner D J; Taylor P
Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action.
Molecular pharmacology 1989;36(3):349-54.
1989: Herz J M; Johnson D A; Taylor P
Distance between the agonist and noncompetitive inhibitor sites on the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1989;264(21):12439-48.
1989: Abramson S N; Li Y; Culver P; Taylor P
An analog of lophotoxin reacts covalently with Tyr190 in the alpha-subunit of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1989;264(21):12666-72.
1989: Abramson S N; Ellisman M H; Deerinck T J; Maulet Y; Gentry M K; Doctor B P; Taylor P
Differences in structure and distribution of the molecular forms of acetylcholinesterase.
The Journal of cell biology 1989;108(6):2301-11.
1989: Ambler S K; Taylor P
Release of nonmitochondrial sequestered Ca2+ from permeabilized muscle cells in culture.
Molecular pharmacology 1989;35(3):369-74.
1988: Schumacher M; Maulet Y; Camp S; Taylor P
Multiple messenger RNA species give rise to the structural diversity in acetylcholinesterase.
The Journal of biological chemistry 1988;263(35):18979-87.
1988: Abramson S N; Culver P; Kline T; Li Y; Guest P; Gutman L; Taylor P
Lophotoxin and related coral toxins covalently label the alpha-subunit of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 1988;263(34):18568-73.
1988: Ambler S K; Poenie M; Tsien R Y; Taylor P
Agonist-stimulated oscillations and cycling of intracellular free calcium in individual cultured muscle cells.
The Journal of biological chemistry 1988;263(4):1952-9.
1988: Gibney G; MacPhee-Quigley K; Thompson B; Vedvick T; Low M G; Taylor S S; Taylor P
Divergence in primary structure between the molecular forms of acetylcholinesterase.
The Journal of biological chemistry 1988;263(3):1140-5.
1987: Ambler S K; Thompson B; Solski P A; Brown J H; Taylor P
Receptor-mediated inositol phosphate formation in relation to calcium mobilization: a comparison of two cell lines.
Molecular pharmacology 1987;32(3):376-83.
1986: Schumacher M; Camp S; Maulet Y; Newton M; MacPhee-Quigley K; Taylor S S; Friedmann T; Taylor P
Primary structure of acetylcholinesterase: implications for regulation and function.
Federation proceedings 1986;45(13):2976-81.
1986: Schumacher M; Camp S; Maulet Y; Newton M; MacPhee-Quigley K; Taylor S S; Friedmann T; Taylor P
Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.
Nature 1986;319(6052):407-9.

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