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Alain Tedgui

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Anne-Clémence Vion; Gilles Chironi; Cecile Devue; Stéphanie Lehoux; Gervaise Loirand; Xavier LOYER; Bhama Ramkhelawon; Alain Tedgui; Chantal M Boulanger
Shear stress regulates endothelial microparticle release.
Nicolas Deroide; James Harrison; Yoichiro Iwakura; Nathalie Kubis; Dominique Lerouet; Xuan Li; Lauren Baker; Isabelle Margaill; Leanne Masters; Lina Nih; Marc Pocard; Marine Poittevin; Bernhard Ryffel; Alain Tedgui; Emily Van Vré; Ziad Mallat
MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury.
Hafid Ait-Oufella; Christoph J Binder; Olivier Blanc-Brude; Christelle Coatrieux; Christophe A Girard; Olivier Herbin; Jeremie Joffre; Sonia Karabina; Charlotte Lahoute; Gérard Lambeau; Ludivine Laurans; Xavier Loyer; Makoto Murakami; Christine Payré; Bhama Ramkhelawon; Alain Tedgui; Kei Yamamoto; Ziad Mallat
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.

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All Publications

2013: Anne-Clémence Vion; Gilles Chironi; Cecile Devue; Stéphanie Lehoux; Gervaise Loirand; Xavier LOYER; Bhama Ramkhelawon; Alain Tedgui; Chantal M Boulanger
Shear stress regulates endothelial microparticle release.
Circulation research 2013;112(10):1323-33.
2013: Nicolas Deroide; James Harrison; Yoichiro Iwakura; Nathalie Kubis; Dominique Lerouet; Xuan Li; Lauren Baker; Isabelle Margaill; Leanne Masters; Lina Nih; Marc Pocard; Marine Poittevin; Bernhard Ryffel; Alain Tedgui; Emily Van Vré; Ziad Mallat
MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury.
The Journal of clinical investigation 2013;123(3):1176-81.
2013: Hafid Ait-Oufella; Christoph J Binder; Olivier Blanc-Brude; Christelle Coatrieux; Christophe A Girard; Olivier Herbin; Jeremie Joffre; Sonia Karabina; Charlotte Lahoute; Gérard Lambeau; Ludivine Laurans; Xavier Loyer; Makoto Murakami; Christine Payré; Bhama Ramkhelawon; Alain Tedgui; Kei Yamamoto; Ziad Mallat
Group X secreted phospholipase A2 limits the development of atherosclerosis in LDL receptor-null mice.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):466-73.
2013: Mélissa Romain; Soraya Taleb; Alain Tedgui; Yu Wang; Akihiko Yoshimura; Marion Dalloz; Bruno Esposito; Nicolas Pérez; Padmapriya Ponnuswamy; Ziad Mallat
Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice--brief report.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):581-4.
2013: Tabassome Simon; Soraya Taleb; Alain Tedgui; Jean-Michel Montely; Benoit Rousseau; Simon Cattan; Nicolas Danchin; Olivier Dubourg; Salma Kotti; Ludivine Laurans; Ziad Mallat
Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction.
European heart journal 2013;34(8):570-7.
2012: Stéphane M Camus; Dominique Charue; Joao A De Moraes; Blandine Gausserès; Linda Grimaud; Laurent Loufrani; Jean-Marie Renard; Alain Tedgui; Pierre-Louis Tharaux; Philippe Bonnin; Chantal M Boulanger; Olivier P Blanc-Brude
Erythrocyte microparticles can induce kidney vaso-occlusions in a murine model of sickle cell disease.
Blood 2012;120(25):5050-8.
2012: Olivier P Blanc-Brude; Alain Tedgui
Feeding sugar to tumors: with a supplement of miR?
Journal of the American Heart Association 2012;1(6):e006213.
2012: Lars Lind; Jacques Machecourt; Ewa Ninio; Tabassome Simon; Alain Tedgui; Håkan Ahlström; Nicolas Danchin; Tomas Hansen; Lars Johansson; Salma Kotti; Ziad Mallat
Circulating levels of secretory- and lipoprotein-associated phospholipase A2 activities: relation to atherosclerotic plaques and future all-cause mortality.
European heart journal 2012;33(23):2946-54.
2012: Kiyohito Arai; Eric Bruckert; M John Chapman; Ziad Mallat; Alexina Orsoni; Alain Tedgui; Alexandros D Tselepis; Joseph L Witztum; Sotirios Tsimikas
Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia.
Journal of lipid research 2012;53(8):1670-8.
2012: Pierre-Emmanuel Rautou; Jean-Marie Renard; Yannis Sainte-Marie; Alain Tedgui; Dominique Valla; Anne-Clemence Vion; Julie Bresson; Cecile Devue; Laure Elkrief; Christophe Heymes; Didier Lebrec; Philippe Letteron; Richard Moreau; Valerie Paradis; Chantal M Boulanger
Abnormal plasma microparticles impair vasoconstrictor responses in patients with cirrhosis.
Gastroenterology 2012;143(1):166-76.e6.
2012: Bernard Prendergast; Nicole Probst-Hensch; Ernst Th Rietschel; Hartmut Rütten; Caroline Steingen; Alain Tedgui; Wiek van Gilst; Heyo K Kroemer; Anne Lücke; Heini Murer; Eike Nagel; Ludwig Neyses; Joep Perk; Leslie T Coope; Harry Crijns; Thomas Eschenhagen; Elisabeth Falkenstein; Ulrich Fölsch; Sigrun Halvorsen; Stefan Janssens; Eero Jokinen; Steen Dalby Kristensen
The German Centre for Cardiovascular Research.
European heart journal 2012;33(9):1033-36,1036a.
2012: Padmapriya Ponnuswamy; Ziad Mallat; Emily A Van Vré; Alain Tedgui
Humoral and cellular immune responses in atherosclerosis: spotlight on B- and T-cells.
Vascular pharmacology 2012;56(5-6):193-203.
2012: Nicolas Amabile; Chantal M Boulanger; Alain P Guérin; Alain Tedgui; Gérard M London
Predictive value of circulating endothelial microparticles for cardiovascular mortality in end-stage renal failure: a pilot study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(5):1873-80.
2012: Emily A Van Vré; Alain Tedgui; Hafid Ait-Oufella; Ziad Mallat
Apoptotic cell death and efferocytosis in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(4):887-93.
2012: Giulia Fornasa; Anh-Thu Gaston; Emilie Groyer; Kevin Guedj; Srini V Kaveri; Jamila Khallou-Laschet; Jean-Baptiste Michel; Marion Morvan; Antonino Nicoletti; Alain Tedgui; Marc Clement; giuseppina caligiuri
A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation.
Cardiovascular research 2012;94(1):30-7.
2012: Olivier Herbin; Hafid Ait-Oufella; Benjamin Aubier; Véronique Barateau; Gunilla Nordin Fredrikson; Jan Nilsson; Nicolas Perez; Alain Tedgui; Wang Yu; Ziad Mallat
Regulatory T-cell response to apolipoprotein B100-derived peptides reduces the development and progression of atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(3):605-12.
2012: Sung Kee Ryu; Gregory G Schwartz; Alain Tedgui; Sotirios Tsimikas; Weihang Bao; Joelle Benessiano; Ziad Mallat; Anders G Olsson
Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes.
Circulation 2012;125(6):757-66.
2012: Marie-Olivia Chandesris; Olivier Clément; Nathalie Aladjidi; Arshid Azarine; Vincent Barlogis; Nathalie Boddaert; Gérard Body; Pierre Boutouyrie; Erwan Bozec; Olivier Hermine; Cyrille Hoarau; Roland Jaussaud; Stéphane Laurent; Yvon Lebranchu; Olivier Lortholary; Ziad Mallat; Elie Mousseaux; Marine Munzer; Kim-Thanh Ong; Capucine Picard; Mélissa Romain; Felipe Suarez; Soraya Taleb; Alain Tedgui; Caroline Thumerelle; Isabelle Tillie-Leblond; François Tron; Alain Fischer
Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency.
Circulation. Cardiovascular genetics 2012;5(1):25-34.
2011: Ahmed Klink; Mark E Lobatto; Ziad Mallat; Maarten Merkx; Willem J M Mulder; Klaas Nicolay; Honorius M H F Sanders; Gustav J Strijkers; Alain Tedgui; Teresa Arias; Valentin Fuster; Beatriz Herranz; Joeri Heynens; Zahi A Fayad
In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging.
Journal of the American College of Cardiology 2011;58(24):2522-30.
2011: Alain Tedgui; A Phillip Owens; Nigel Mackman
2011 Nobel Prize in Physiology or Medicine: Toll-like receptors, dendritic cells, and their roles in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(12):2767-8.
2011: Amir Ravandi; Philippa J Talmud; Alain Tedgui; Joelle Benessiano; S Matthijs Boekholdt; John J P Kastelein; Kay-Tee Khaw; Ziad Mallat; Elizabeth R Miller; Nicholas J Wareham; Joseph L Witztum; Sotirios Tsimikas
Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study.
Journal of lipid research 2011;52(10):1829-36.
2011: Michelle L O'Donoghue; Torbjørn Omland; Sarah Sloan; Scott D Solomon; Alain Tedgui; Joelle Benessiano; Eugene Braunwald; Ziad Mallat; David A Morrow; Marc S Sabatine
Prognostic utility of secretory phospholipase A(2) in patients with stable coronary artery disease.
Clinical chemistry 2011;57(9):1311-7.
2011: Pierre-Emmanuel Rautou; Alain Simon; Alain Tedgui; Anne-Clémence Vion; Nicolas Amabile; Gilles Chironi; Chantal M Boulanger
Microparticles, vascular function, and atherothrombosis.
Circulation research 2011;109(5):593-606.
2011: Charlotte Lahoute; Olivier Herbin; Ziad Mallat; Alain Tedgui
Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets.
Nature reviews. Cardiology 2011;8(6):348-58.
2011: Jonathan Golledge; Ziad Mallat; Alain Tedgui; Paul E Norman
Serum secreted phospholipase A2 is associated with abdominal aortic aneurysm presence but not progression.
Atherosclerosis 2011;216(2):458-60.
2011: Hafid Ait-Oufella; Soraya Taleb; Ziad Mallat; Alain Tedgui
Recent advances on the role of cytokines in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(5):969-79.
2011: Alain Tedgui
Focus on inflammation.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(5):958-9.
2011: Eric Tartour; H Pere; Bernard Maillere; M Terme; N Merillon; J Taieb; F Sandoval; Françoise Quintin-Colonna; K Lacerda; A Karadimou; Cécile Badoual; Alain Tedgui; Wolf H Fridman; Stéphane Oudard
Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy.
Cancer metastasis reviews 2011;30(1):83-95.
2011: Pierre-Emmanuel Rautou; Aurélie S Leroyer; Bhama Ramkhelawon; Cécile Devue; Dominique Duflaut; Anne-Clémence Vion; Gilles Nalbone; Yves Castier; Guy Leseche; Stéphanie Lehoux; Alain Tedgui; Chantal M Boulanger
Microparticles from human atherosclerotic plaques promote endothelial ICAM-1-dependent monocyte adhesion and transendothelial migration.
Circulation research 2011;108(3):335-43.
2010: Ziad Mallat; Gérard Lambeau; Alain Tedgui
Lipoprotein-associated and secreted phospholipases A₂ in cardiovascular disease: roles as biological effectors and biomarkers.
Circulation 2010;122(21):2183-200.
2010: Laurence Bal; Stéphane Ederhy; Emanuele Di Angelantonio; Florence Toti; Fatiha Zobairi; Ghislaine Dufaitre; Catherine Meuleman; Ziad Mallat; Franck Boccara; Alain Tedgui; Jean-Marie Freyssinet; Ariel Cohen
Circulating procoagulant microparticles in acute pulmonary embolism: a case-control study.
International journal of cardiology 2010;145(2):321-2.
2010: Nicolas Amabile; Pierre-Emmanuel Rautou; Alain Tedgui; Chantal M Boulanger
Microparticles: key protagonists in cardiovascular disorders.
Seminars in thrombosis and hemostasis 2010;36(8):907-16.
2010: Hafid Ait-Oufella; Yu Wang; Olivier Herbin; Alain Tedgui; Ziad Mallat
[Role of TGF-ß in a model of abdominal aortic aneurysm in mice].
Médecine sciences : M/S 2010;26(10):795-7.
2010: Soraya Taleb; Alain Tedgui; Ziad Mallat
Interleukin-17: friend or foe in atherosclerosis?
Current opinion in lipidology 2010;21(5):404-8.
2010: Sotirios Tsimikas; Ziad Mallat; Philippa J Talmud; John J P Kastelein; Nicholas J Wareham; Manjinder S Sandhu; Elizabeth R Miller; Joelle Benessiano; Alain Tedgui; Joseph L Witztum; Kay-Tee Khaw; S Matthijs Boekholdt
Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events.
Journal of the American College of Cardiology 2010;56(12):946-55.
2010: Hafid Ait-Oufella; Olivier Herbin; Jean-David Bouaziz; Christoph J Binder; Catherine Uyttenhove; Ludivine Laurans; Soraya Taleb; Emily Van Vré; Bruno Esposito; José Vilar; Jérôme Sirvent; Jacques Van Snick; Alain Tedgui; Thomas F Tedder; Ziad Mallat
B cell depletion reduces the development of atherosclerosis in mice.
The Journal of experimental medicine 2010;207(8):1579-87.
2010: Laurence Bal; Stéphane Ederhy; Emanuele Di Angelantonio; Florence Toti; Fatiha Zobairi; Ghislaine Dufaitre; Catherine Meuleman; Ziad Mallat; Franck Boccara; Alain Tedgui; Jean-Marie Freyssinet; Ariel Cohen
Factors influencing the level of circulating procoagulant microparticles in acute pulmonary embolism.
Archives of cardiovascular diseases 2010;103(6-7):394-403.
2010: Soraya Taleb; Alain Tedgui; Ziad Mallat
Adaptive T cell immune responses and atherogenesis.
Current opinion in pharmacology 2010;10(2):197-202.
2010: Gilles N Chironi; Alain Simon; Chantal M Boulanger; Françoise Dignat-George; Bénédicte Hugel; Jean-Louis Megnien; Muriel Lefort; Jean-Marie Freyssinet; Alain Tedgui
Circulating microparticles may influence early carotid artery remodeling.
Journal of hypertension 2010;28(4):789-96.
2010: Anne Forest; Eric Pautas; Patrick Ray; Dominique Bonnet; Marc Verny; Nicolas Amabile; Chantal Boulanger; Bruno Riou; Alain Tedgui; Ziad Mallat; Jacques Boddaert
Circulating microparticles and procoagulant activity in elderly patients.
The journals of gerontology. Series A, Biological sciences and medical sciences 2010;65(4):414-20.
2010: Sadri Chahed; Aurélie S Leroyer; Mounir Benzerroug; david gaucher; Adriana Georgescu; Serge Picaud; Jean-Sébastien Silvestre; alain gaudric; Alain Tedgui; Pascale Massin; Chantal M Boulanger
Increased vitreous shedding of microparticles in proliferative diabetic retinopathy stimulates endothelial proliferation.
Diabetes 2010;59(3):694-701.
2010: Yu Wang; Hafid Ait-Oufella; Olivier Herbin; Philippe Bonnin; Bhama Ramkhelawon; Soraya Taleb; Jin Huang; Georges Offenstadt; Christophe Combadière; Laurent Rénia; Jason L Johnson; Pierre-Louis Tharaux; Alain Tedgui; Ziad Mallat
TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.
The Journal of clinical investigation 2010;120(2):422-32.
2009: Philippe Eren; Stéphane Camus; Gianfranco Matrone; Téni G Ebrahimian; Delphine François; Alain Tedgui; Jean Sébastien Silvestre; Olivier Blanc-Brude
Adiponectinemia controls pro-angiogenic cell therapy.
Stem cells (Dayton, Ohio) 2009;27(11):2712-21.
2009: Bhama Ramkhelawon; Jose Vilar; Daniel Rivas; Barend Mees; Rini de Crom; Alain Tedgui; Stéphanie Lehoux
Shear stress regulates angiotensin type 1 receptor expression in endothelial cells.
Circulation research 2009;105(9):869-75.
2009: Soraya Taleb; Mélissa Romain; Bhama Ramkhelawon; Catherine Uyttenhove; Gerard Pasterkamp; Olivier Herbin; Bruno Esposito; Nicolas Perez; Hideo Yasukawa; Jacques Van Snick; Akihiko Yoshimura; Alain Tedgui; Ziad Mallat
Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis.
The Journal of experimental medicine 2009;206(10):2067-77.
2009: Manuel Mayr; David Grainger; Ursula Mayr; Aurelie S Leroyer; Guy Leseche; Anissa Sidibe; Olivier Herbin; Xiaoke Yin; Aldrin Gomes; Basetti Madhu; John R Griffiths; Qingbo Xu; Alain Tedgui; Chantal M Boulanger
Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
Circulation. Cardiovascular genetics 2009;2(4):379-88.
2009: Karin R Sipido; Alain Tedgui; Steen D Kristensen; Gerard Pasterkamp; Heribert Schunkert; Martin Wehling; Philippe Gabriel STEG; Wolfgang Eisert; Frank Rademakers; Barbara Casadei; Valentin Fuster; Elisabetta Cerbai; Gerd Hasenfuss; Francisco Fernandez-Aviles; David Garcia-Dorado; Maria Vidal; Manuel Hallen; Virginija Dambrauskaite
Identifying needs and opportunities for advancing translational research in cardiovascular disease.
Cardiovascular research 2009;83(3):425-35.
2009: Yves Castier; Bhama Ramkhelawon; Stéphanie Riou; Alain Tedgui; Stephanie Lehoux
Role of NF-kappaB in flow-induced vascular remodeling.
Antioxidants & redox signaling 2009;11(7):1641-9.
2009: Aurelie S Leroyer; Téni G Ebrahimian; Clément Cochain; Alice Récalde; Olivier Blanc-Brude; Barend Mees; José Vilar; Alain Tedgui; Bernard I Levy; Giovanna Chimini; Chantal M Boulanger; Jean-Sébastien Silvestre
Microparticles from ischemic muscle promotes postnatal vasculogenesis.
Circulation 2009;119(21):2808-17.
2009: Hafid Ait-Oufella; Soraya Taleb; Ziad Mallat; Alain Tedgui
Cytokine network and T cell immunity in atherosclerosis.
Seminars in immunopathology 2009;31(1):23-33.
2009: Ziad Mallat; Soraya Taleb; Hafid Ait-Oufella; Alain Tedgui
The role of adaptive T cell immunity in atherosclerosis.
Journal of lipid research 2009;50 Suppl():S364-9.
2009: Gilles N Chironi; Chantal M Boulanger; Alain Simon; Françoise Dignat-George; Jean-Marie Freyssinet; Alain Tedgui
Endothelial microparticles in diseases.
Cell and tissue research 2009;335(1):143-51.
2009: Ziad Mallat; Tabassome Simon; Joelle Benessiano; Karine Clément; Soraya Taleb; Nicholas J Wareham; Robert Luben; Kay-Tee Khaw; Alain Tedgui; S Matthijs Boekholdt
Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women.
The Journal of clinical endocrinology and metabolism 2009;94(1):255-60.
2008: Aurélie S Leroyer; Pierre-Emmanuel Rautou; Jean-Sébastien Silvestre; Yves Castier; Guy Lesèche; Cécile Devue; Micheline Duriez; Ralf P Brandes; Esther Lutgens; Alain Tedgui; Chantal M Boulanger
CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization.
Journal of the American College of Cardiology 2008;52(16):1302-11.
2008: Hafid Ait-Oufella; Vahid Pouresmail; Tabassome Simon; Olivier Blanc-Brude; Kiyoka Kinugawa; Régine Merval; Georges Offenstadt; Guy Lesèche; Philip L Cohen; Alain Tedgui; Ziad Mallat
Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(8):1429-31.
2008: Jean-Marc LaBlanche; Nicolas Danchin; Michel Farnier; Alain Tedgui; Eric Vicaut; Joaquim Alonso; Peter Crean; Attilio Leone; Joao Morais; Massimo Santini; Muriel Licour; Mohamed Farah; Jean-Claude Tardif
Effects of rosuvastatin and atorvastatin on the apolipoprotein B/apolipoprotein A-1 ratio in patients with an acute coronary syndrome: The CENTAURUS trial design.
Archives of cardiovascular diseases 2008;101(6):399-406.
2008: Ziad Mallat; Alain Tedgui
HDL, PTX3, and vascular protection.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):809-11.
2008: Aurélie S Leroyer; Alain Tedgui; C M Boulanger
Role of microparticles in atherothrombosis.
Journal of internal medicine 2008;263(5):528-37.
2008: Jean-Sebastien Silvestre; Bernard I Lévy; Alain Tedgui
Mechanisms of angiogenesis and remodelling of the microvasculature.
Cardiovascular research 2008;78(2):201-2.
2008: Jean-Sebastien Silvestre; Ziad Mallat; Alain Tedgui; Bernard I Lévy
Post-ischaemic neovascularization and inflammation.
Cardiovascular research 2008;78(2):242-9.
2008: Christophe Combadière; Stephane Potteaux; Mathieu Rodero; Tabassome Simon; Adeline Pezard; Bruno Esposito; Régine Merval; Amanda Proudfoot; Alain Tedgui; Ziad Mallat
Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice.
Circulation 2008;117(13):1649-57.
2008: Audrey Billon; Stéphanie Lehoux; Laetitia Lam Shang Leen; Henrik Laurell; Cédric Filipe; Vincent Benouaich; Laurent Brouchet; Chantal Dessy; Pierre Gourdy; Alain-Pierre Gadeau; Alain Tedgui; Jean-Luc Balligand; Jean-François Arnal
The estrogen effects on endothelial repair and mitogen-activated protein kinase activation are abolished in endothelial nitric-oxide (NO) synthase knockout mice, but not by NO synthase inhibition by N-nitro-L-arginine methyl ester.
The American journal of pathology 2008;172(3):830-8.
2008: Aurélie S Leroyer; Alain Tedgui; C M Boulanger
Microparticles and type 2 diabetes.
Diabetes & metabolism 2008;34 Suppl 1():S27-32.
2008: Joffrey Zoll; Vincent Fontaine; Pierre Gourdy; Véronique Barateau; José Vilar; Aurélie S Leroyer; Izolina Lopes-Kam; Ziad Mallat; Jean-François Arnal; Patrick Henry; Gérard Tobelem; Alain Tedgui
Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition.
Cardiovascular research 2008;77(3):471-80.
2007: Ziad Mallat; Alain Tedgui
Cytokines as regulators of atherosclerosis in murine models.
Current drug targets 2007;8(12):1264-72.
2007: Soraya Taleb; Olivier Herbin; Hafid Ait-Oufella; Wim Verreth; Pierre Gourdy; Véronique Barateau; Régine Merval; Bruno Esposito; Karine Clément; Paul Holvoet; Alain Tedgui; Ziad Mallat
Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2691-8.
2007: Matthias Canault; Aurélie S Leroyer; Franck Peiretti; Guy Lesèche; Alain Tedgui; Bernadette Bonardo; Marie-Christine Alessi; Chantal M Boulanger; Gilles Nalbone
Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1.
The American journal of pathology 2007;171(5):1713-23.
2007: Hafid Ait-Oufella; Branka Horvat; Yann M Kerdiles; Olivier Herbin; Pierre Gourdy; Jamila Khallou-Laschet; Régine Merval; Bruno Esposito; Alain Tedgui; Ziad Mallat
Measles virus nucleoprotein induces a regulatory immune response and reduces atherosclerosis in mice.
Circulation 2007;116(15):1707-13.
2007: Stéphane Ederhy; Emanuele Di Angelantonio; Ziad Mallat; Bénédicte Hugel; Sandra Janower; Catherine Meuleman; Franck Boccara; Jean-Marie Freyssinet; Alain Tedgui; Ariel Cohen
Levels of circulating procoagulant microparticles in nonvalvular atrial fibrillation.
The American journal of cardiology 2007;100(6):989-94.
2007: Martin Flamant; Sandrine Placier; Caroline Dubroca; Bruno Esposito; Izolina Lopes; Christos Chatziantoniou; Alain Tedgui; Jean-Claude Dussaule; Stéphanie Lehoux
Role of matrix metalloproteinases in early hypertensive vascular remodeling.
Hypertension 2007;50(1):212-8.
2007: Ziad Mallat; Hafid Ait-Oufella; Alain Tedgui
Regulatory T-cell immunity in atherosclerosis.
Trends in cardiovascular medicine 2007;17(4):113-8.
2007: Ziad Mallat; Joelle Benessiano; Tabassome Simon; Stéphane Ederhy; Carla Sebella-Arguelles; Ariel Cohen; Virginie Huart; Nicholas J Wareham; Robert Luben; Kay-Tee Khaw; Alain Tedgui; S Matthijs Boekholdt
Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(5):1177-83.
2007: Stéphanie Riou; Barend Mees; Bruno Esposito; Régine Merval; José Vilar; DOMINIQuE STENGEL; Ewa Ninio; Rien van Haperen; Rini de Crom; Alain Tedgui; Stéphanie Lehoux
High pressure promotes monocyte adhesion to the vascular wall.
Circulation research 2007;100(8):1226-33.
2007: Hafid Ait-Oufella; Kiyoka Kinugawa; Joffrey Zoll; Tabassome Simon; Jacques Boddaert; Sylvia Heeneman; Olivier Blanc-Brude; Véronique Barateau; Stephane Potteaux; Régine Merval; Bruno Esposito; Elisabeth Teissier; Mat J A P Daemen; Guy Lesèche; Chantal M Boulanger; Alain Tedgui; Ziad Mallat
Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice.
Circulation 2007;115(16):2168-77.
2007: Chantal M Boulanger; Nicolas Amabile; Alain P Guérin; Bruno Pannier; Aurélie S Leroyer; Clément Nguyen Ziad Mallat; Alain Tedgui; Gérard M London
In vivo shear stress determines circulating levels of endothelial microparticles in end-stage renal disease.
Hypertension 2007;49(4):902-8.
2007: Olivier Blanc-Brude; Elisabeth Teissier; Yves Castier; Guy Lesèche; Ann-Pascal Bijnens; Mat Daemen; Bart Staels; Ziad Mallat; Alain Tedgui
IAP survivin regulates atherosclerotic macrophage survival.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):901-7.
2007: Jacques Boddaert; Kiyoka Kinugawa; jean-charles lambert; Fatiha Boukhtouche; Joffrey Zoll; Régine Merval; Olivier Blanc-Brude; D M A Mann; Claudine Berr; José Vilar; Béatrice Garabedian; Nathalie Journiac; Dominique Charue; Jean-Sébastien Silvestre; Charles Duyckaerts; Philippe Amouyel; Jean Mariani; Alain Tedgui; Ziad Mallat
Evidence of a role for lactadherin in Alzheimer's disease.
The American journal of pathology 2007;170(3):921-9.
2007: Aurélie S Leroyer; Hirotaka Isobe; Guy Lesèche; Yves Castier; Michel Wassef; Ziad Mallat; Bernd R Binder; Alain Tedgui; Chantal M Boulanger
Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques.
Journal of the American College of Cardiology 2007;49(7):772-7.
2006: Gilles Chironi; Alain Simon; Bénédicte Hugel; Muriel Del-Pino; Jerome Gariepy; Jean-Marie Freyssinet; Alain Tedgui
Circulating leukocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjects.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2775-80.
2006: Catherine A Lemarié; Pierre-Louis Tharaux; Bruno Esposito; Alain Tedgui; Stéphanie Lehoux
Transforming growth factor-alpha mediates nuclear factor kappaB activation in strained arteries.
Circulation research 2006;99(4):434-41.
2006: Philippe Gabriel STEG; philippe ravaud; Alain Tedgui; Jacques Puel; Dominique Moyse; Emmanuelle Curaudeau; Steven W Quentzel
Predischarge C-reactive protein and 1-year outcome after acute coronary syndromes.
The American journal of medicine 2006;119(8):684-92.
2006: Chantal M Boulanger; Nicolas Amabile; Alain Tedgui
Circulating microparticles: a potential prognostic marker for atherosclerotic vascular disease.
Hypertension 2006;48(2):180-6.
2006: Stephane Potteaux; Christophe Combadière; Bruno Esposito; Cedric Lecureuil; Hafid Ait-Oufella; Régine Merval; Patrice Ardouin; Alain Tedgui; Ziad Mallat
Role of bone marrow-derived CC-chemokine receptor 5 in the development of atherosclerosis of low-density lipoprotein receptor knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1858-63.
2006: Yves Castier; Stéphanie Lehoux; Y Hu; Georgios Foteinos; G Fonteinos; Alain Tedgui; Q Xu
Characterization of neointima lesions associated with arteriovenous fistulas in a mouse model.
Kidney international 2006;70(2):315-20.
2006: Alain Tedgui; Ziad Mallat
Cytokines in atherosclerosis: pathogenic and regulatory pathways.
Physiological reviews 2006;86(2):515-81.
2006: Stéphanie Lehoux; Yves Castier; Alain Tedgui
Molecular mechanisms of the vascular responses to haemodynamic forces.
Journal of internal medicine 2006;259(4):381-92.
2006: Stephane Potteaux; Virginie Deleuze; Régine Merval; Michel F Bureau; Bruno Esposito; Daniel Scherman; Alain Tedgui; Ziad Mallat
In vivo electrotransfer of interleukin-10 cDNA prevents endothelial upregulation of activated NF-kappaB and adhesion molecules following an atherogenic diet.
European cytokine network 2006;17(1):13-8.
2006: Hafid Ait-Oufella; Benoît L Salomon; Stephane Potteaux; Anna-Karin L Robertson; Pierre Gourdy; Joffrey Zoll; Régine Merval; Bruno Esposito; José L Cohen; Sylvain Fisson; Richard A Flavell; Göran K Hansson; David Klatzmann; Alain Tedgui; Ziad Mallat
Natural regulatory T cells control the development of atherosclerosis in mice.
Nature medicine 2006;12(2):178-80.
2005: Nicolas Amabile; Alain P Guérin; Aurélie S Leroyer; Ziad Mallat; Clément Nguyen; Jacques Boddaert; Gérard M London; Alain Tedgui; Chantal M Boulanger
Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure.
Journal of the American Society of Nephrology : JASN 2005;16(11):3381-8.
2005: Ziad Mallat; Philippe Gabriel STEG; Joelle Benessiano; Marie-Laure Tanguy; Keith A Fox; Jean-Philippe Collet; Omar H Dabbous; Patrick Henry; Kathryn F Carruthers; Anne Dauphin; Carla Sibella Arguelles; Joëlle Masliah; Bénédicte Hugel; Gilles Montalescot; Jean-Marie Freyssinet; Bernard Asselain; Alain Tedgui
Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes.
Journal of the American College of Cardiology 2005;46(7):1249-57.
2005: Ziad Mallat; Hafid Ait-Oufella; Alain Tedgui
Regulatory T cell responses: potential role in the control of atherosclerosis.
Current opinion in lipidology 2005;16(5):518-24.
2005: Yves Castier; Ralf P Brandes; Guy Leseche; Alain Tedgui; Stéphanie Lehoux
p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling.
Circulation research 2005;97(6):533-40.
2005: Jean-Sébastien Silvestre; Clotilde Théry; Bernard I Lévy; Alain Tedgui; Sebastian Amigorena; Ziad Mallat
[Lactadherin promotes VEGF-dependent neovascularization].
Médecine sciences : M/S 2005;21(8-9):683-5.
2005: Chantal M Boulanger; Alain Tedgui
Dying for attention: microparticles and angiogenesis.
Cardiovascular research 2005;67(1):1-3.
2005: Jacques Boddaert; Ziad Mallat; Paul Fornes; Bruno Esposito; Dominique Lecomte; Marc Verny; Alain Tedgui; Joël Belmin
Age and gender effects on apoptosis in the human coronary arterial wall.
Mechanisms of ageing and development 2005;126(6-7):678-84.
2005: Stéphanie Lehoux; Alain Tedgui
Making up and breaking up: the tortuous ways of the vascular wall.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):892-4.
2005: Jean-Sébastien Silvestre; Clotilde Théry; Ghislaine Hamard; Jacques Boddaert; Barbara Aguilar; Alain Delcayre; Christophe Houbron; Radia Tamarat; Olivier Blanc-Brude; Sylvia Heeneman; Michel Clergue; Micheline Duriez; Régine Merval; Bernard I Lévy; Alain Tedgui; Sebastian Amigorena; Ziad Mallat
Lactadherin promotes VEGF-dependent neovascularization.
Nature medicine 2005;11(5):499-506.
2005: Ludovic Waeckel; Ziad Mallat; Stephane Potteaux; Christophe Combadière; Michel Clergue; Micheline Duriez; Lu Bao; Craig Gerard; Barrett J Rollins; Alain Tedgui; Bernard I Levy; Jean-Sébastien Silvestre
Impairment in postischemic neovascularization in mice lacking the CXC chemokine receptor 3.
Circulation research 2005;96(5):576-82.
2005: Stéphanie Lehoux; Bruno Esposito; Régine Merval; Alain Tedgui
Differential regulation of vascular focal adhesion kinase by steady stretch and pulsatility.
Circulation 2005;111(5):643-9.
2005: Alain Tedgui
The role of inflammation in atherothrombosis: implications for clinical practice.
Vascular medicine (London, England) 2005;10(1):45-53.
2005: Stephane Potteaux; Christophe Combadière; Bruno Esposito; Saveria Casanova; Régine Merval; Patrice Ardouin; Ji-Liang Gao; Philip M Murphy; Alain Tedgui; Ziad Mallat
Chemokine receptor CCR1 disruption in bone marrow cells enhances atherosclerotic lesion development and inflammation in mice.
Molecular medicine (Cambridge, Mass.) 2005;11(1-12):16-20.
2004: Ziad Mallat; Christophe Heymes; Anne Corbaz; Damien Logeart; Sami Alouani; Alain Cohen-Solal; Tim Seidler; Gerd Hasenfuss; Yolande Chvatchko; Ajay M Shah; Alain Tedgui
Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1752-4.
2004: Ziad Mallat; Alain Tedgui
Immunomodulation to combat atherosclerosis: the potential role of immune regulatory cells.
Expert opinion on biological therapy 2004;4(9):1387-93.
2004: Alain Tedgui; Ziad Mallat
Hypertension: a novel regulator of adaptive immunity in atherosclerosis?
Hypertension 2004;44(3):257-8.
2004: Stephane Potteaux; Bruno Esposito; Olivia van Oostrom; Valérie Brun; Patrice Ardouin; Hervé Groux; Alain Tedgui; Ziad Mallat
Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1474-8.
2004: E Durand; A Scoazec; antoine lafont; Jacques Boddaert; A Al Hajzen; Faouzi Addad; Massoud Mirshahi; Michel Desnos; Alain Tedgui; Ziad Mallat
In vivo induction of endothelial apoptosis leads to vessel thrombosis and endothelial denudation: a clue to the understanding of the mechanisms of thrombotic plaque erosion.
Circulation 2004;109(21):2503-6.
2004: Stéphanie Lehoux; Alain Tedgui
[Shear and signal transduction in the endothelial cell].
Médecine sciences : M/S 2004;20(5):551-6.
2004: Fatiha Boukhtouche; Jean Mariani; Alain Tedgui
The "CholesteROR" protective pathway in the vascular system.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):637-43.
2004: Stéphanie Lehoux; Catherine A Lemarié; Bruno Esposito; H Roger Lijnen; Alain Tedgui
Pressure-induced matrix metalloproteinase-9 contributes to early hypertensive remodeling.
Circulation 2004;109(8):1041-7.
2004: Ziad Mallat; Alain Tedgui
[Apoptosis and acute coronary syndromes].
Médecine sciences : M/S 2004;20(3):298-303.
2004: Valérie Planat-Benard; Jean-Sébastien Silvestre; Béatrice Cousin; Mireille André; Maryse Nibbelink; Radia Tamarat; Michel Clergue; Carole Manneville; Corinne Saillan-Barreau; Micheline Duriez; Alain Tedgui; Bernard Levy; Luc Pénicaud; Louis Casteilla
Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives.
Circulation 2004;109(5):656-63.
2003: Stéphanie Lehoux; Alain Tedgui
All strain, no gain: stretch keeps proliferation at bay via the NF-kappaB response gene iex-1.
Circulation research 2003;93(12):1139-41.
2003: Jean-Sébastien Silvestre; Andrea Gojova; Valérie Brun; Stephane Potteaux; Bruno Esposito; Micheline Duriez; Michel Clergue; Sophie Le Ricousse-Roussanne; Véronique Barateau; Régine Merval; Hervé Groux; Gérard Tobelem; Bernard Levy; Alain Tedgui; Ziad Mallat
Transplantation of bone marrow-derived mononuclear cells in ischemic apolipoprotein E-knockout mice accelerates atherosclerosis without altering plaque composition.
Circulation 2003;108(23):2839-42.
2003: Andrea Gojova; Valérie Brun; Bruno Esposito; Françoise Cottrez; Pierre Gourdy; Patrice Ardouin; Alain Tedgui; Ziad Mallat; Hervé Groux
Specific abrogation of transforming growth factor-beta signaling in T cells alters atherosclerotic lesion size and composition in mice.
Blood 2003;102(12):4052-8.
2003: Ziad Mallat; Andrea Gojova; Vincent Sauzeau; Valérie Brun; Jean-Sébastien Silvestre; Bruno Esposito; Régine Merval; Hervé Groux; Gervaise Loirand; Alain Tedgui
Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice.
Circulation research 2003;93(9):884-8.
2003: Marie-Clotilde Alves-Guerra; Sophie Rousset; Claire Pecqueur; Ziad Mallat; Julie Blanc; Alain Tedgui; Frederic Bouillaud; Anne-Marie Cassard-Doulcier; Daniel Ricquier; Bruno Miroux
Bone marrow transplantation reveals the in vivo expression of the mitochondrial uncoupling protein 2 in immune and nonimmune cells during inflammation.
The Journal of biological chemistry 2003;278(43):42307-12.
2003: Ziad Mallat; Andrea Gojova; Valérie Brun; Bruno Esposito; Nathalie Fournier; Françoise Cottrez; Alain Tedgui; Hervé Groux
Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice.
Circulation 2003;108(10):1232-7.
2003: Catherine A Lemarié; Bruno Esposito; Alain Tedgui; Stéphanie Lehoux
Pressure-induced vascular activation of nuclear factor-kappaB: role in cell survival.
Circulation research 2003;93(3):207-12.
2003: Stéphanie Lehoux; Alain Tedgui
Cellular mechanics and gene expression in blood vessels.
Journal of biomechanics 2003;36(5):631-43.
2003: Alain Tedgui; Ziad Mallat
[Acute coronary thrombosis].
La Revue du praticien 2003;53(6):602-6.
2003: Christophe Combadière; Stephane Potteaux; Ji-Liang Gao; Bruno Esposito; Saveria Casanova; Eric J Lee; Patrice Debré; Alain Tedgui; Philip M Murphy; Ziad Mallat
Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice.
Circulation 2003;107(7):1009-16.
2003: J Blanc; Marie-Clotilde Alves-Guerra; Bruno Esposito; Sophie Rousset; Pierre Gourdy; Daniel Ricquier; Alain Tedgui; Bruno Miroux; Ziad Mallat
Protective role of uncoupling protein 2 in atherosclerosis.
Circulation 2003;107(3):388-90.
2002: Hélène Duez; Yu-Sheng Chao; Melba Hernandez; Gérard Torpier; Philippe Poulain; Steven S Mundt; Ziad Mallat; Elisabeth Teissier; Charlotte A Burton; Alain Tedgui; Jean-Charles Fruchart; Catherine Fiévet; Samuel D Wright; Bart Staels
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
The Journal of biological chemistry 2002;277(50):48051-7.
2002: Ziad Mallat; P Henry; R Fressonnet; Sami Alouani; A Scoazec; Philippe Beaufils; Yolande Chvatchko; Alain Tedgui
Increased plasma concentrations of interleukin-18 in acute coronary syndromes.
Heart (British Cardiac Society) 2002;88(5):467-9.
2002: Ziad Mallat; Alain Tedgui
The role of transforming growth factor beta in atherosclerosis: novel insights and future perspectives.
Current opinion in lipidology 2002;13(5):523-9.
2002: Ziad Mallat; Jean-Sébastien Silvestre; Sophie Le Ricousse-Roussanne; Laurence Lecomte-Raclet; Anne Corbaz; Michel Clergue; Micheline Duriez; Véronique Barateau; Shizuo Akira; Alain Tedgui; Gérard Tobelem; Yolande Chvatchko; Bernard I Lévy
Interleukin-18/interleukin-18 binding protein signaling modulates ischemia-induced neovascularization in mice hindlimb.
Circulation research 2002;91(5):441-8.
2002: Alain Tedgui; Ziad Mallat
Platelets in atherosclerosis: a new role for beta-amyloid peptide beyond Alzheimer's disease.
Circulation research 2002;90(11):1145-6.
2002: Eric Durand; Ziad Mallat; Faouzi Addad; Françoise Vilde; Michel Desnos; Claude Guérot; Alain Tedgui; antoine lafont
Time courses of apoptosis and cell proliferation and their relationship to arterial remodeling and restenosis after angioplasty in an atherosclerotic rabbit model.
Journal of the American College of Cardiology 2002;39(10):1680-5.
2002: Sandrine Besnard; Joëlle Bakouche; Yolande Lemaigre-Dubreuil; Jean Mariani; Alain Tedgui; Daniel Henrion
Smooth muscle dysfunction in resistance arteries of the staggerer mouse, a mutant of the nuclear receptor RORalpha.
Circulation research 2002;90(7):820-5.
2002: Nathalie Kubis; Sandrine Besnard; Jean-Sébastien Silvestre; Michel Feletou; Paul L Huang; Bernard I Lévy; Alain Tedgui
Decreased arteriolar density in endothelial nitric oxide synthase knockout mice is due to hypertension, not to the constitutive defect in endothelial nitric oxide synthase enzyme.
Journal of hypertension 2002;20(2):273-80.
2002: Sandrine Besnard; Christophe Heymes; Régine Merval; Marianne Rodriguez; Jean-Pierre Galizzi; Jean A Boutin; Jean Mariani; Alain Tedgui
Expression and regulation of the nuclear receptor RORalpha in human vascular cells.
FEBS letters 2002;511(1-3):36-40.
2002: Christopher I Jarvis; Bart Staels; Bernard Brugg; Yolande Lemaigre-Dubreuil; Alain Tedgui; Jean Mariani
Age-related phenotypes in the staggerer mouse expand the RORalpha nuclear receptor's role beyond the cerebellum.
Molecular and cellular endocrinology 2002;186(1):1-5.
2002: Stéphanie Lehoux; François Tronc; Alain Tedgui
Mechanisms of blood flow-induced vascular enlargement.
Biorheology 2002;39(3-4):319-24.
2001: Sandrine Besnard; Jean-Sébastien Silvestre; Micheline Duriez; Joëlle Bakouche; Yolande Lemaigre-Dubreuil; Jean Mariani; Bernard I Levy; Alain Tedgui
Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha.
Circulation research 2001;89(12):1209-15.
2001: Chantal M Boulanger; A Scoazec; Téni G Ebrahimian; P Henry; Eric Mathieu; Alain Tedgui; Ziad Mallat
Circulating microparticles from patients with myocardial infarction cause endothelial dysfunction.
Circulation 2001;104(22):2649-52.
2001: Ziad Mallat; Andrea Gojova; Carmen Marchiol-Fournigault; Bruno Esposito; C Kamaté; Régine Merval; Didier Fradelizi; Alain Tedgui
Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.
Circulation research 2001;89(10):930-4.
2001: Ziad Mallat; Paul Fornes; R Costagliola; Bruno Esposito; Joël Belmin; Dominique Lecomte; Alain Tedgui
Age and gender effects on cardiomyocyte apoptosis in the normal human heart.
The journals of gerontology. Series A, Biological sciences and medical sciences 2001;56(11):M719-23.
2001: Ziad Mallat; Anne Corbaz; A Scoazec; Sandrine Besnard; Guy Lesèche; Yolande Chvatchko; Alain Tedgui
Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability.
Circulation 2001;104(14):1598-603.
2001: Ziad Mallat; Anne Corbaz; A Scoazec; Pierre Graber; Sami Alouani; Bruno Esposito; Y Humbert; Yolande Chvatchko; Alain Tedgui
Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability.
Circulation research 2001;89(7):E41-5.
2001: Jean-Sébastien Silvestre; Ziad Mallat; Radia Tamarat; Micheline Duriez; Alain Tedgui; Bernard I Levy
Regulation of matrix metalloproteinase activity in ischemic tissue by interleukin-10: role in ischemia-induced angiogenesis.
Circulation research 2001;89(3):259-64.
2001: Khalid Matrougui; Laszlo Tanko; Laurent Loufrani; Diane Gorny; Bernard I Levy; Alain Tedgui; Daniel Henrion
Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(8):1288-93.
2001: Rima Elhage; S Clamens; Sandrine Besnard; Ziad Mallat; Alain Tedgui; Jean-François Arnal; Arlette Maret; Francis Bayard
Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice.
Atherosclerosis 2001;156(2):315-20.
2001: Nathalie Kubis; A Checoury; Alain Tedgui; Bernard I Lévy
Adaptive common carotid arteries remodeling after unilateral internal carotid artery occlusion in adult patients.
Cardiovascular research 2001;50(3):597-602.
2001: Ziad Mallat; Alain Tedgui
Current perspective on the role of apoptosis in atherothrombotic disease.
Circulation research 2001;88(10):998-1003.
2001: Alain Tedgui; Ziad Mallat
Anti-inflammatory mechanisms in the vascular wall.
Circulation research 2001;88(9):877-87.
2001: Eric Raspé; Hélène Duez; Philippe Gervois; Catherine Fiévet; Jean-Charles Fruchart; Sandrine Besnard; Jean Mariani; Alain Tedgui; Bart Staels
Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha.
The Journal of biological chemistry 2001;276(4):2865-71.
2000: François Tronc; Ziad Mallat; Stéphanie Lehoux; M Wassef; Bruno Esposito; Alain Tedgui
Role of matrix metalloproteinases in blood flow-induced arterial enlargement: interaction with NO.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(12):E120-6.
2000: Stéphanie Lehoux; Bruno Esposito; Régine Merval; Laurent Loufrani; Alain Tedgui
Pulsatile stretch-induced extracellular signal-regulated kinase 1/2 activation in organ culture of rabbit aorta involves reactive oxygen species.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2366-72.
2000: Khalid Matrougui; Yvonne E G Eskildsen-Helmond; A Fiebeler; Daniel Henrion; Bernard I Levy; Alain Tedgui; Michael J Mulvany
Angiotensin II stimulates extracellular signal-regulated kinase activity in intact pressurized rat mesenteric resistance arteries.
Hypertension 2000;36(4):617-21.
2000: Jean-Sébastien Silvestre; Ziad Mallat; Micheline Duriez; Radia Tamarat; Michel F Bureau; Daniel Scherman; Nicolas Duverger; Didier Branellec; Alain Tedgui; Bernard I Levy
Antiangiogenic effect of interleukin-10 in ischemia-induced angiogenesis in mice hindlimb.
Circulation research 2000;87(6):448-52.
2000: Claudia Mitchell; Alexandre Mignon; Jacques-Emmanuel Guidotti; Sandrine Besnard; Monique Fabre; Nicolas Duverger; D Parlier; Alain Tedgui; Axel Kahn; Hélène Gilgenkrantz
Therapeutic liver repopulation in a mouse model of hypercholesterolemia.
Human molecular genetics 2000;9(11):1597-602.
2000: O Tricot; Ziad Mallat; Christophe Heymes; J Belmin; Guy Lesèche; Alain Tedgui
Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques.
Circulation 2000;101(21):2450-3.
2000: Giulia Chinetti; F G Gbaguidi; Sabine Griglio; Ziad Mallat; M Antonucci; Philippe Poulain; J Chapman; Jean-Charles Fruchart; Alain Tedgui; J Najib-Fruchart; Bart Staels
CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors.
Circulation 2000;101(20):2411-7.
2000: Ziad Mallat; Hakim Benamer; Bénédicte Hugel; Joelle Benessiano; Philippe Gabriel STEG; Jean-Marie Freyssinet; Alain Tedgui
Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes.
Circulation 2000;101(8):841-3.
1999: C Bernard; Régine Merval; Marilyne Lebret; Philippe Delerive; Isabelle Dusanter-Fourt; Stéphanie Lehoux; Christophe Créminon; Bart Staels; Jacques Maclouf; Alain Tedgui
Oncostatin M induces interleukin-6 and cyclooxygenase-2 expression in human vascular smooth muscle cells : synergy with interleukin-1beta.
Circulation research 1999;85(12):1124-31.
1999: Alain Tedgui; Ziad Mallat
[Atherosclerotic plaque formation].
La Revue du praticien 1999;49(19):2081-6.
1999: Laurent Loufrani; Stéphanie Lehoux; Alain Tedgui; Bernard I Lévy; Daniel Henrion
Stretch induces mitogen-activated protein kinase activation and myogenic tone through 2 distinct pathways.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(12):2878-83.
1999: Philippe Delerive; Karolien De Bosscher; S Besnard; Wim Vanden Berghe; J M Peters; F J Gonzalez; Jean-Charles Fruchart; Alain Tedgui; Guy Haegeman; Bart Staels
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.
The Journal of biological chemistry 1999;274(45):32048-54.
1999: Ziad Mallat; Sandrine Besnard; Micheline Duriez; Virginie Deleuze; Florence Emmanuel; Michel F Bureau; Florent Soubrier; Bruno Esposito; Hélène Duez; Catherine Fievet; Bart Staels; Nicolas Duverger; Daniel Scherman; Alain Tedgui
Protective role of interleukin-10 in atherosclerosis.
Circulation research 1999;85(8):e17-24.
1999: Ziad Mallat; Alain Tedgui
[Apoptosis in the cardiovascular system].
Annales de pathologie 1999;19(3):265-73.
1999: Ziad Mallat; Christophe Heymes; J Ohan; Elisabetta Faggin; Guy Lesèche; Alain Tedgui
Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):611-6.
1999: Ziad Mallat; T Nakamura; J Ohan; Guy Lesèche; Alain Tedgui; Jacques Maclouf; R C Murphy
The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis.
The Journal of clinical investigation 1999;103(3):421-7.
1999: Ziad Mallat; Bénédicte Hugel; J Ohan; Guy Lesèche; Jean-Marie Freyssinet; Alain Tedgui
Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity.
Circulation 1999;99(3):348-53.
1999: Alain Tedgui; Ziad Mallat
[Apoptosis and vascular remodeling].
Thérapie 1999;54(1):167-70.
1998: Stéphanie Lehoux; Alain Tedgui
Signal transduction of mechanical stresses in the vascular wall.
Hypertension 1998;32(2):338-45.
1998: Bart Staels; W Koenig; Aida Habib; Régine Merval; Marilyne Lebret; Inés Pineda Torra; Philippe Delerive; A Fadel; Giulia Chinetti; Jean-Charles Fruchart; J Najib; J Maclouf; Alain Tedgui
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Nature 1998;393(6687):790-3.
1998: Konstantin G Birukov; N Bardy; Stéphanie Lehoux; Régine Merval; Vladimir P Shirinsky; Alain Tedgui
Intraluminal pressure is essential for the maintenance of smooth muscle caldesmon and filamin content in aortic organ culture.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(6):922-7.
1998: Alain Tedgui; Ziad Mallat; Stéphanie Lehoux
External stenting & atherosclerosis.
Nature medicine 1998;4(6):645.
1998: C Bernard; Régine Merval; Bruno Esposito; Alain Tedgui
Resistance to endotoxin shock in spontaneously hypertensive rats.
Hypertension 1998;31(6):1350-6.
1998: Ziad Mallat; Ivan Philip; Marilyne Lebret; D Chatel; Jacques Maclouf; Alain Tedgui
Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure.
Circulation 1998;97(16):1536-9.
1997: Alain Tedgui
[Role of the endothelium in atherosclerosis].
La Revue du praticien 1997;47(20):2262-7.
1997: Konstantin G Birukov; Stéphanie Lehoux; Anna A Birukova; Régine Merval; V A Tkachuk; Alain Tedgui
Increased pressure induces sustained protein kinase C-independent herbimycin A-sensitive activation of extracellular signal-related kinase 1/2 in the rabbit aorta in organ culture.
Circulation research 1997;81(6):895-903.
1997: Ngoc Vu-Dac; Philippe Gervois; T Grötzinger; P De Vos; K Schoonjans; Jean-Charles Fruchart; J Auwerx; Jean Mariani; Alain Tedgui; Bart Staels
Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha.
The Journal of biological chemistry 1997;272(36):22401-4.
1997: Ziad Mallat; J Ohan; Guy Lesèche; Alain Tedgui
Colocalization of CPP-32 with apoptotic cells in human atherosclerotic plaques.
Circulation 1997;96(2):424-8.
1997: Jean-Louis Beaudeux; M L Césarini; Monique Gardès-Albert; Jacques Maclouf; Régine Merval; Bruno Esposito; Jacqueline Peynet; Alain Tedgui
Native and gamma radiolysis-oxidized lipoprotein(a) increase the adhesiveness of rabbit aortic endothelium.
Atherosclerosis 1997;132(1):29-35.
1997: Aida Habib; C Bernard; Marilyne Lebret; Christophe Creminon; Bruno Esposito; Alain Tedgui; Jacques Maclouf
Regulation of the expression of cyclooxygenase-2 by nitric oxide in rat peritoneal macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3845-51.
1996: F Tronc; M Wassef; Bruno Esposito; Daniel Henrion; S Glagov; Alain Tedgui
Role of NO in flow-induced remodeling of the rabbit common carotid artery.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(10):1256-62.
1996: H Y Qiu; C Bernard; Khalid Matrougui; Alain Tedgui; Bernard I Levy
Rapid effect of LPS-activated macrophages on the reactivity of the rat mesenteric artery.
Journal of vascular research 1996;33(5):370-9.
1996: G Meyer; Régine Merval; Alain Tedgui
Effects of pressure-induced stretch and convection on low-density lipoprotein and albumin uptake in the rabbit aortic wall.
Circulation research 1996;79(3):532-40.
1996: N Bardy; Régine Merval; Joelle Benessiano; Jane-Lise Samuel; Alain Tedgui
Pressure and angiotensin II synergistically induce aortic fibronectin expression in organ culture model of rabbit aorta. Evidence for a pressure-induced tissue renin-angiotensin system.
Circulation research 1996;79(1):70-8.
1995: J H Kennedy; Alain Tedgui
Normal and pathological aspects of mass transport across the vascular wall.
Cardiovascular surgery (London, England) 1995;3(6):611-5.
1995: Philippe Menasché; Jacqueline Peynet; nicole Haeffner-Cavaillon; M P Carreno; T de Chaumaray; V Dillisse; B Faris; A Piwnica; G Bloch; Alain Tedgui
Influence of temperature on neutrophil trafficking during clinical cardiopulmonary bypass.
Circulation 1995;92(9 Suppl):II334-40.
1995: Philippe Menasché; Jacqueline Peynet; F Le Deist; M P Carreno; nicole Haeffner-Cavaillon; V Dillisse; J Larivière; A Piwnica; G Bloch; Alain Tedgui
[Does temperature in extracorporeal circulation affect neutrophil-endothelium interactions?].
Archives des maladies du coeur et des vaisseaux 1995;88(10):1415-23.
1995: N Bardy; G J Karillon; Régine Merval; Jane-Lise Samuel; Alain Tedgui
Differential effects of pressure and flow on DNA and protein synthesis and on fibronectin expression by arteries in a novel organ culture system.
Circulation research 1995;77(4):684-94.
1995: L Caputo; Alain Tedgui; Bernard I Lévy
Control of carotid vasomotor tone by local renin-angiotensin system in normotensive and spontaneously hypertensive rats. Role of endothelium and flow.
Circulation research 1995;77(2):303-9.
1995: J Belmin; C Bernard; Bruno Corman; Régine Merval; Bruno Esposito; Alain Tedgui
Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats.
The American journal of physiology 1995;268(6 Pt 2):H2288-93.
1995: C Bernard; P Barnier; Régine Merval; Bruno Esposito; Alain Tedgui
Pentoxifylline selectivity inhibits tumor necrosis factor synthesis in the arterial wall.
Journal of cardiovascular pharmacology 1995;25 Suppl 2():S30-3.
1995: Jorge Boczkowski; I Philip; Alain Tedgui; C Bernard; Régine Merval; Jean-Marie Desmonts; Michel Aubier
Effects of inhibition of nitric oxide synthesis on TNF alpha serum levels in E. coli endotoxemic rats.
Life sciences 1995;57(13):PL147-52.
1994: Philippe Menasché; Jacqueline Peynet; J Larivière; F Tronc; A Piwnica; G Bloch; Alain Tedgui
Does normothermia during cardiopulmonary bypass increase neutrophil-endothelium interactions?
Circulation 1994;90(5 Pt 2):II275-9.
1994: N Bardy; Régine Merval; Jane-Lise Samuel; Alain Tedgui
[Effects of angiotensin II and pressure on cellular fibronectin in the vascular wall in organotypic culture].
Archives des maladies du coeur et des vaisseaux 1994;87(8):991-5.
1994: C Bernard; Régine Merval; Bruno Esposito; Alain Tedgui
Elevated temperature accelerates and amplifies the induction of nitric oxide synthesis in rat macrophages.
European journal of pharmacology 1994;270(1):115-8.
1994: Philippe Menasché; Sam Haydar; Jacqueline Peynet; C Du Buit; Régine Merval; G Bloch; A Piwnica; Alain Tedgui
A potential mechanism of vasodilation after warm heart surgery. The temperature-dependent release of cytokines.
The Journal of thoracic and cardiovascular surgery 1994;107(1):293-9.
1993: G J Karrillon; Régine Merval; Micheline Duriez; Alain Tedgui
[Effects of de-endothelialization and angiotensin II on the vascular remodeling in a model of rabbit aorta organ culture].
Archives des maladies du coeur et des vaisseaux 1993;86(8):1201-6.
1993: J Belmin; Bruno Corman; Régine Merval; Alain Tedgui
Age-related changes in endothelial permeability and distribution volume of albumin in rat aorta.
The American journal of physiology 1993;264(3 Pt 2):H679-85.
1993: J Batellier; M Wassef; Régine Merval; Micheline Duriez; Alain Tedgui
Protection from atherosclerosis in vein grafts by a rigid external support.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(3):379-84.
1993: Alain Tedgui
[Mechanisms of vascular hypertrophy in hypertension].
Archives des maladies du coeur et des vaisseaux 1993;86 Spec No 1():67-72.
1992: Alain Tedgui; Régine Merval; Bruno Esposito
Albumin transport characteristics of rat aorta in early phase of hypertension.
Circulation research 1992;71(4):932-42.
1992: J Batellier; M Wassef; Régine Merval; Micheline Duriez; Alain Tedgui
[Atherosclerosis of an arterialized venous graft. Reduction by rigid external support].
Archives des maladies du coeur et des vaisseaux 1992;85(8):1213-7.
1992: L Caputo; Alain Tedgui; P Poitevin; Bernard I Lévy
In vitro assessment of diameter-pressure relationship in carotid arteries from normotensive and spontaneously hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1992;10(6):S27-30.
1992: C Bernard; B Szekely; I Philip; E Wollman; D Payen; Alain Tedgui
Activated macrophages depress the contractility of rabbit carotids via an L-arginine/nitric oxide-dependent effector mechanism. Connection with amplified cytokine release.
The Journal of clinical investigation 1992;89(3):851-60.
1991: J Belmin; Jean-Baptiste Michel; P A Curmi; J L Salzmann; L Juan; Alain Tedgui
Reduction of transmural 125I-albumin concentration in rat aortic media by chronic hypertension.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(2):334-43.
1990: J H Kennedy; Alain Tedgui; A Piwnica
Vein graft permeability.
The Annals of thoracic surgery 1990;50(2):334.
1990: P A Curmi; L Juan; Régine Merval; Alain Tedgui
[Effects of arterial hyperpression on the transport and distribution of LDL and albumin in the arterial wall].
Archives des maladies du coeur et des vaisseaux 1990;83(8):1329-33.
1990: J Belmin; L Juan; Alain Tedgui
[Measurement of water, DNA and collagen in different parts of the aorta in rats. Effect of hypertension].
Archives des maladies du coeur et des vaisseaux 1990;83(8):1305-7.
1990: P A Curmi; L Juan; Alain Tedgui
Effect of transmural pressure on low density lipoprotein and albumin transport and distribution across the intact arterial wall.
Circulation research 1990;66(6):1692-702.
1989: J H Kennedy; Alain Tedgui; L Juan; A Lavergne; A Piwnica
Effect of peroperative hypertension on 125I-albumin uptake by vein graft media.
The Journal of cardiovascular surgery 1989;30(6):985-8.
1989: Alain Tedgui; S Walter; L Juan; O Azogui
[Adherence of monocytes to the aortic endothelium. Effect of the intraluminal pressure].
Archives des maladies du coeur et des vaisseaux 1989;82(7):1191-4.
1989: P A Curmi; G Renaud; L Juan; B Chiron; Alain Tedgui
Role of LDL receptors in the in vitro uptake and degradation of LDL in the media of rabbit thoracic aorta.
Circulation research 1989;64(5):957-67.
1989: J B Michel; Alain Tedgui; J L Salzmann; J Belmain; Bernard I Lévy
[Function and structure of the vascular wall in experimental arterial hypertension. Effect of treatment].
Néphrologie 1989;10(2):55-7.
1989: P A Curmi; Alain Tedgui
[Effects of transmural pressure on the transport and distribution of low density lipoproteins in the arterial wall].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1989;308(6):149-54.
1988: J H Kennedy; Alain Tedgui; P Mesnildrey; F Laborde; A Lavergne; A Piwnica
Aortic 125I-albumin transport in patients with Marfan's syndrome and annuloaortic ectasia.
Atherosclerosis 1988;73(1):33-7.