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Babu Tekwani

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Chemicals & Drugs

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Nafees Ahmed; Keyur G Brahmbhatt; Melissa Jacob; Ikhlas A Khan; Shabana I Khan; Debashis Mitra; Sudeep Sabde; Inder P Singh; Babu L Tekwani; Kamlesh Kumar Bhutani
Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal, and anti-HIV activities.
Bharathi Avula; Narayan D Chaurasiya; Mahmoud A ElSohly; Ikhlas A Khan; Shabana I Khan; JD McChesney; Rajnish Sahu; Babu L Tekwani; Yan-Hong Wang; N P Dhammika Nanayakkara; Vijender R Adelli; Larry A Walker
Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling.
Muhammad Ilias; Melissa R Jacob; Shabana I Khan; Babu L Tekwani; Larry A Walker; Mohamed A Ibrahim; Vladimir Samoylenko
Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5.

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All Publications

2013: Nafees Ahmed; Keyur G Brahmbhatt; Melissa Jacob; Ikhlas A Khan; Shabana I Khan; Debashis Mitra; Sudeep Sabde; Inder P Singh; Babu L Tekwani; Kamlesh Kumar Bhutani
Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal, and anti-HIV activities.
Chemical biology & drug design 2013;81(4):491-8.
2013: Bharathi Avula; Narayan D Chaurasiya; Mahmoud A ElSohly; Ikhlas A Khan; Shabana I Khan; JD McChesney; Rajnish Sahu; Babu L Tekwani; Yan-Hong Wang; N P Dhammika Nanayakkara; Vijender R Adelli; Larry A Walker
Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling.
Journal of mass spectrometry : JMS 2013;48(2):276-85.
2012: Muhammad Ilias; Melissa R Jacob; Shabana I Khan; Babu L Tekwani; Larry A Walker; Mohamed A Ibrahim; Vladimir Samoylenko
Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5.
Planta medica 2012;78(15):1690-7.
2012: Francis Machumi; Jacob O Midiwo; Matthias Heydenreich; Shabana I Khan; Erich Kleinpeter; Babu L Tekwani; Larry A Walker; Abiy Yenesew; Ilias Muhammad
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
Natural product communications 2012;7(9):1123-6.
2012: Kevin Lewellyn; Babu L Tekwani; Dobroslawa Bialonska; Narayan D Chaurasiya; Jordan K Zjawiony
Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.
Bioorganic & medicinal chemistry letters 2012;22(15):4926-9.
2012: Kirandeep Kaur; Shabana I Khan; Prati Pal Singh; Savita Singh; Babu L Tekwani; Melissa R Jacob; Meenakshi Jain; Rahul Jain
Amino acid, dipeptide and pseudodipeptide conjugates of ring-substituted 8-aminoquinolines: synthesis and evaluation of anti-infective, β-haematin inhibition and cytotoxic activities.
European journal of medicinal chemistry 2012;52():230-41.
2012: Mallika Kumarihamy; Babu L Tekwani; Stephen O Duke; Daneel Ferreira; Melissa Jacob; Shabana I Khan; N P Dhammika Nanayakkara
Antiprotozoal and antimicrobial compounds from the plant pathogen Septoria pistaciarum.
Journal of natural products 2012;75(5):883-9.
2012: Shobana Ganesan; Rajnish Sahu; Narayan D Chaurasiya; Larry A Walker; Babu L Tekwani
Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.
Toxicology 2012;294(1):54-60.
2012: Narayan D Chaurasiya; Luiza R S Dias; Shobana Ganesan; N P Dhammika Nanayakkara; Larry A Walker; Babu L Tekwani
Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.
Bioorganic & medicinal chemistry letters 2012;22(4):1701-4.
2012: Andrea P Caminos; Esteban A Panozzo-Zenere; Babu L Tekwani; Shane R Wilkinson; Guillermo R Labadie
Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines.
Bioorganic & medicinal chemistry letters 2012;22(4):1712-5.
2012: Surendra K Jain; Rajnish Sahu; Larry A Walker; Babu L Tekwani
A parasite rescue and transformation assay for antileishmanial screening against intracellular Leishmania donovani amastigotes in THP1 human acute monocytic leukemia cell line.
Journal of visualized experiments : JoVE 2012;(70):.
2011: Aziz Abdur Rahman; Rajnish Sahu; Volodymyr Samoylenko; Babu L Tekwani; Melissa R Jacob; Surendra K Jain; Shabana I Khan; Ilias Muhammad
Antiparasitic and antimicrobial indolizidines from the leaves of Prosopis glandulosa var. glandulosa.
Planta medica 2011;77(14):1639-43.
2011: Bharathi Avula; Shabana I Khan; JD McChesney; Babu L Tekwani; Larry A Walker; N P Dhammika Nanayakkara; Ikhlas A Khan
Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.
Biomedical chromatography : BMC 2011;25(9):1010-7.
2011: María F Plano; Babu L Tekwani; Melissa R Jacob; Guillermo R Labadie; Raquel M Cravero
An entry to curcuphenol/elvirol core structures via a retro-Aldol reaction.
Chemistry & biodiversity 2011;8(6):1098-111.
2011: Falgun Shah; Prasenjit Mukherjee; Jiri Gut; Jennifer Legac; Philip J Rosenthal; Babu L Tekwani; Mitchell A Avery
Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
Journal of chemical information and modeling 2011;51(4):852-64.
2011: Kirandeep Kaur; Meenakshi Jain; Shabana I Khan; Melissa R Jacob; Babu L Tekwani; Savita Singh; Prati Pal Singh; Rahul Jain
Synthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines).
Bioorganic & medicinal chemistry 2011;19(1):197-210.
2010: Joanna Bajsa; Adam McCluskey; Christopher P Gordon; Scott G Stewart; Timothy A Hill; Rajnish Sahu; Stephen O Duke; Babu L Tekwani
The antiplasmodial activity of norcantharidin analogs.
Bioorganic & medicinal chemistry letters 2010;20(22):6688-95.
2010: Sandra C Mwakwari; William Guerrant; Vishal Patil; Shabana I Khan; Babu L Tekwani; Zachary A Gurard-Levin; Milan Mrksich; Adegboyega K Oyelere
Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.
Journal of medicinal chemistry 2010;53(16):6100-11.
2010: William Guerrant; Sandra C Mwakwari; Po-Chih Chen; Shabana I Khan; Babu L Tekwani; Adegboyega K Oyelere
A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.
ChemMedChem 2010;5(8):1232-5.
2010: Francis Machumi; Volodymyr Samoylenko; Abiy Yenesew; Solomon Derese; Jacob O Midiwo; Frank T Wiggers; Melissa R Jacob; Babu L Tekwani; Shabana I Khan; Larry Walker; Ilias Muhammad
Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum.
Natural product communications 2010;5(6):853-8.
2010: Yan-Hong Wang; Volodymyr Samoylenko; Babu L Tekwani; Ikhlas A Khan; Loren S Miller; Narayan D Chaurasiya; Md Mostafizur Rahman; Lalit M Tripathi; Shabana I Khan; Vaishali C Joshi; Frank T Wigger; Ilias Muhammad
Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease.
Journal of ethnopharmacology 2010;128(3):662-71.
2010: Shobana Ganesan; Rajnish Sahu; Larry Walker; Babu L Tekwani
Cytochrome P450-dependent toxicity of dapsone in human erythrocytes.
Journal of applied toxicology : JAT 2010;30(3):271-5.
2010: MinKyun Na; Yuanqing Ding; Bin Wang; Babu L Tekwani; Ray F Schinazi; Scott Franzblau; Michelle Kelly; Robert Stone; Xing-Cong Li; Daneel Ferreira; Mark T Hamann
Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia.
Journal of natural products 2010;73(3):383-7.
2010: Volodymyr Samoylenko; Md Mostafizur Rahman; Babu L Tekwani; Lalit M Tripathi; Yan-Hong Wang; Shabana I Khan; Ikhlas A Khan; Loren S Miller; Vaishali C Joshi; Ilias Muhammad
Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease.
Journal of ethnopharmacology 2010;127(2):357-67.
2010: Jiangnan Peng; Sucheta Kudrimoti; Sivaprakasam Prasanna; Srinivas Odde; Robert J Doerksen; Hari K Pennaka; Yeun-Mun Choo; Karumanchi V Rao; Babu L Tekwani; Vamsi Madgula; Shabana I Khan; Bin Wang; Alejandro M S Mayer; Melissa R Jacob; Lan Chun Tu; Jürg Gertsch; Mark T Hamann
Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
Journal of medicinal chemistry 2010;53(1):61-76.
2010: Vishal Patil; William Guerrant; Po-Chih Chen; Berkley Gryder; Derek B Benicewicz; Shabana I Khan; Babu L Tekwani; Adegboyega K Oyelere
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.
Bioorganic & medicinal chemistry 2010;18(1):415-25.
2009: H M T Bandara Herath; Wimal Herath; Paulo Carvalho; Shabana I Khan; Babu L Tekwani; Stephen O Duke; Maria Tomaso-Peterson; N P Dhammika Nanayakkara
Biologically active tetranorditerpenoids from the fungus Sclerotinia homoeocarpa causal agent of dollar spot in turfgrass.
Journal of natural products 2009;72(12):2091-7.
2009: Desmond Slade; Ahmed M Galal; Waseem Gul; Mohamed M Radwan; Safwat A Ahmed; Shabana I Khan; Babu L Tekwani; Melissa R Jacob; Samir A Ross; Mahmoud A ElSohly
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.
Bioorganic & medicinal chemistry 2009;17(23):7949-57.
2009: Amir E Wahba; Jiangnan Peng; Sucheta Kudrimoti; Babu L Tekwani; Mark T Hamann
Structure-activity relationship studies of manzamine A: amidation of positions 6 and 8 of the beta-carboline moiety.
Bioorganic & medicinal chemistry 2009;17(22):7775-82.
2009: Shobana Ganesan; Babu L Tekwani; Rajnish Sahu; Lalit M Tripathi; Larry Walker
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.
Toxicology and applied pharmacology 2009;241(1):14-22.
2009: Anupam Pradhan; abhai Tripathi; Prashant V Desai; Prasenjit K Mukherjee; Mitchell A Avery; Larry Walker; Babu L Tekwani
Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.
Biochimie 2009;91(11-12):1509-17.
2009: Volodymyr Samoylenko; Melissa R Jacob; Shabana I Khan; Jianping Zhao; Babu L Tekwani; Jacob O Midiwo; Larry Walker; Ilias Muhammad
Antimicrobial, antiparasitic and cytotoxic spermine alkaloids from Albizia schimperiana.
Natural product communications 2009;4(6):791-6.
2009: Anupam Pradhan; Prasenjit Mukherjee; abhai Tripathi; Mitchell A Avery; Larry Walker; Babu L Tekwani
Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants.
Molecular and cellular biochemistry 2009;325(1-2):141-8.
2009: M O Faruk Khan; Mark S Levi; Babu L Tekwani; Shabana I Khan; Eiichi Kimura; Ronald F Borne
Synthesis and antimalarial activities of cyclen 4-aminoquinoline analogs.
Antimicrobial agents and chemotherapy 2009;53(4):1320-4.
2009: Volodymyr Samoylenko; Shabana I Khan; Melissa R Jacoba; Babu L Tekwani; Larry Walker; Charles D Hufford; Ilias Muhammad
Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations.
Natural product communications 2009;4(2):185-92.
2009: Volodymyr Samoylenko; Mohammad K Ashfaq; Melissa R Jacob; Babu L Tekwani; Shabana I Khan; Susan P Manly; Vaishali C Joshi; Larry Walker; Ilias Muhammad
Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa.
Journal of natural products 2009;72(1):92-8.
2008: Joanna Bajsa; Stephen O Duke; Babu L Tekwani
Plasmodium falciparum serine/threonine phoshoprotein phosphatases (PPP): from housekeeper to the 'holy grail'.
Current drug targets 2008;9(11):997-1012.
2008: Babu L Tekwani
Current antiparasitic drug targets and a paradigm shift in discovery of new antiparasitic drugs and vaccines.
Current drug targets 2008;9(11):921.
2008: Daniela G Rando; Mitchell Avery; Babu L Tekwani; Shabana I Khan; Elizabeth I Ferreira
Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides.
Bioorganic & medicinal chemistry 2008;16(14):6724-31.
2008: Abbas Gholipour Shilabin; Noer Kasanah; Babu L Tekwani; Mark T Hamann
Kinetic studies and bioactivity of potential manzamine prodrugs.
Journal of natural products 2008;71(7):1218-21.
2008: Prasenjit Mukherjee; Prashant V Desai; Anuradha Srivastava; Babu L Tekwani; Mitchell A Avery
Probing the structures of leishmanial farnesyl pyrophosphate synthases: homology modeling and docking studies.
Journal of chemical information and modeling 2008;48(5):1026-40.
2008: Prasenjit Mukherjee; Anupam Pradhan; Falgun Shah; Babu L Tekwani; Mitchell A Avery
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy.
Bioorganic & medicinal chemistry 2008;16(9):5254-65.
2008: Annie Mayence; Aurélie Pietka; Margaret S Collins; Melanie T Cushion; Babu L Tekwani; Tien L Huang; Jean Jacques Vanden Eynde
Novel bisbenzimidazoles with antileishmanial effectiveness.
Bioorganic & medicinal chemistry letters 2008;18(8):2658-61.
2008: Babu L Tekwani
Infectious disorders drug targets--an arsenal of knowledge on pathogen targets.
Infectious disorders drug targets 2008;8(1):46-7.
2008: Anuradha Srivastava; Prasenjit Mukherjee; Prashant V Desai; Mitchell A Avery; Babu L Tekwani
Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target.
Infectious disorders drug targets 2008;8(1):16-30.
2008: Mahmood Reza Moein; Rahul Pawar; Shabana I Khan; Babu L Tekwani; Ikhlas A Khan
Antileishmanial, antiplasmodial and cytotoxic activities of 12,16-dideoxy aegyptinone B from Zhumeria majdae Rech.f. & Wendelbo.
Phytotherapy research : PTR 2008;22(3):283-5.
2008: Sandip B Bharate; Shabana I Khan; Babu L Tekwani; Melissa Jacob; Ikhlas A Khan; Inder Pal Singh
S-Euglobals: biomimetic synthesis, antileishmanial, antimalarial, and antimicrobial activities.
Bioorganic & medicinal chemistry 2008;16(3):1328-36.
2007: Kshipra Singh; Ameeta Agarwal; Shabana I Khan; Larry Walker; Babu L Tekwani
Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected].
Journal of biomolecular screening 2007;12(8):1109-14.
2007: Joanna Bajsa; Kshipra Singh; Dhammika Nanayakkara; Stephen O Duke; Agnes M Rimando; Antonio Evidente; Babu L Tekwani
A survey of synthetic and natural phytotoxic compounds and phytoalexins as potential antimalarial compounds.
Biological & pharmaceutical bulletin 2007;30(9):1740-4.
2007: seoung choi; Anupam Pradhan; Nicholas Hammond; Amar G Chittiboyina; Babu L Tekwani; Mitchell A Avery
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors.
Journal of medicinal chemistry 2007;50(16):3841-50.
2007: M O Faruk Khan; Mark S Levi; Babu L Tekwani; Norman H Wilson; Ronald F Borne
Synthesis of isoquinuclidine analogs of chloroquine: antimalarial and antileishmanial activity.
Bioorganic & medicinal chemistry 2007;15(11):3919-25.
2007: seoung choi; Aaron B Beeler; Anupam Pradhan; E Blake Watkins; John M Rimoldi; Babu L Tekwani; Mitchell A Avery
Generation of oxamic acid libraries: antimalarials and inhibitors of Plasmodium falciparum lactate dehydrogenase.
Journal of combinatorial chemistry 2007;9(2):292-300.
2007: Kirandeep Kaur; Sanjay R Patel; Premanand Patil; Meenakshi Jain; Shabana I Khan; Melissa R Jacob; Shobana Ganesan; Babu L Tekwani; Rahul Jain
Synthesis, antimalarial, antileishmanial, antimicrobial, cytotoxicity, and methemoglobin (MetHB) formation activities of new 8-quinolinamines.
Bioorganic & medicinal chemistry 2007;15(2):915-30.
2007: Sandip B Bharate; Shabana I Khan; Nafees A M Yunus; Siddheshwar K Chauthe; Melissa R Jacob; Babu L Tekwani; Ikhlas A Khan; Inder Pal Singh
Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.
Bioorganic & medicinal chemistry 2007;15(1):87-96.
2006: Rani B Menon; Muraleedharan M Kannoth; Babu L Tekwani; Jiri Gut; Philip J Rosenthal; Mitchell A Avery
A new library of C-16 modified artemisinin analogs and evaluation of their anti-parasitic activities.
Combinatorial chemistry & high throughput screening 2006;9(10):729-41.
2006: Babu L Tekwani; Larry Walker
8-Aminoquinolines: future role as antiprotozoal drugs.
Current opinion in infectious diseases 2006;19(6):623-31.
2006: Nikolas Fokialakis; Eleftherios Kalpoutzakis; Babu L Tekwani; Alexios-Leandros Skaltsounis; Stephen O Duke
Antileishmanial activity of natural diterpenes from Cistus sp. and semisynthetic derivatives thereof.
Biological & pharmaceutical bulletin 2006;29(8):1775-8.
2006: Tien L Huang; Jean Jacques Vanden Eynde; Annie Mayence; Isaac O Donkor; Shabana I Khan; Babu L Tekwani
Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners.
The Journal of pharmacy and pharmacology 2006;58(8):1033-42.
2006: Karumanchi V Rao; Marwa Donia; Jiangnan Peng; Esther Garcia-Palomero; Diana Alonso; Ana Martinez; Miguel Medina; Scott Franzblau; Babu L Tekwani; Shabana I Khan; Subagus Wahyuono; Kristine L Willett; Mark T Hamann
Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases.
Journal of natural products 2006;69(7):1034-40.
2006: Sridevi Ankisetty; Hala N ElSohly; Xing-Cong Li; Shabana I Khan; Babu L Tekwani; Troy J Smillie; Larry Walker
Aromatic constituents of Uvaria grandiflora.
Journal of natural products 2006;69(4):692-4.
2006: Sandip B Bharate; Kamlesh K Bhutani; Shabana I Khan; Babu L Tekwani; Melissa R Jacob; Ikhlas A Khan; Inder Pal Singh
Biomimetic synthesis, antimicrobial, antileishmanial and antimalarial activities of euglobals and their analogues.
Bioorganic & medicinal chemistry 2006;14(6):1750-60.
2006: Prashant V Desai; Akshay Patny; Jiri Gut; Philip J Rosenthal; Babu L Tekwani; Anuradha Srivastava; Mitchell Avery
Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory.
Journal of medicinal chemistry 2006;49(5):1576-84.
2005: Meenakshi Jain; Shabana I Khan; Babu L Tekwani; Melissa R Jacob; Savita Singh; Prati Pal Singh; Rahul Jain
Synthesis, antimalarial, antileishmanial, and antimicrobial activities of some 8-quinolinamine analogues.
Bioorganic & medicinal chemistry 2005;13(14):4458-66.
2005: Rosa M Reguera; Babu L Tekwani; Rafael Balaña-Fouce
Polyamine transport in parasites: a potential target for new antiparasitic drug development.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2005;140(2):151-64.
2005: Deborah A Thiem; Albert T Sneden; Shabana I Khan; Babu L Tekwani
Bisnortriterpenes from Salacia madagascariensis.
Journal of natural products 2005;68(2):251-4.
2005: Babu L Tekwani; Larry Walker
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.
Combinatorial chemistry & high throughput screening 2005;8(1):63-79.
2004: Prashant V Desai; Akshay Patny; Yogesh A Sabnis; Babu L Tekwani; Jiri Gut; Philip Rosenthal; Anuradha Srivastava; Mitchell Avery
Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
Journal of medicinal chemistry 2004;47(26):6609-15.
2004: Guoyi Ma; Shabana I Khan; Melissa R Jacob; Babu L Tekwani; Zuqiang Li; David S Pasco; Larry Walker; Ikhlas A Khan
Antimicrobial and antileishmanial activities of hypocrellins A and B.
Antimicrobial agents and chemotherapy 2004;48(11):4450-2.
2004: abhai Tripathi; Prashant V Desai; Anupam Pradhan; Shabana I Khan; Mitchell A Avery; Larry Walker; Babu L Tekwani
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.
European journal of biochemistry / FEBS 2004;271(17):3488-502.
2004: Karumanchi V Rao; Noer Kasanah; Subagus Wahyuono; Babu L Tekwani; Ray F Schinazi; Mark T Hamann
Three new manzamine alkaloids from a common Indonesian sponge and their activity against infectious and tropical parasitic diseases.
Journal of natural products 2004;67(8):1314-8.
2004: Annie Mayence; Jean Jacques Vanden Eynde; Louis LeCour; Larry Walker; Babu L Tekwani; Tien L Huang
Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents.
European journal of medicinal chemistry 2004;39(6):547-53.
2004: Ilias Muhammad; Erdal Bedir; Shabana I Khan; Babu L Tekwani; Ikhlas A Khan; Satoshi Takamatsu; Jerry Pelletier; Larry Walker
A new antimalarial quassinoid from Simaba orinocensis.
Journal of natural products 2004;67(5):772-7.
2004: Antonello Mai; Ilaria Cerbara; Sergio Valente; Silvio Massa; Larry Walker; Babu L Tekwani
Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors.
Antimicrobial agents and chemotherapy 2004;48(4):1435-6.
2004: abhai Tripathi; Shabana I Khan; Larry Walker; Babu L Tekwani
Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay.
Analytical biochemistry 2004;325(1):85-91.
2003: Héctor Villa; Yolanda Pérez-Pertejo; Carlos García-Estrada; Rosa M Reguera; José María Requena; Babu L Tekwani; Rafael Balaña-Fouce; David Ordóñez
Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.
European journal of biochemistry / FEBS 2003;270(21):4339-47.
2003: Anil K Tripathi; Rupesh Chaturvedi; Rizwan Ahmad; Mohammad Asim; Kamal K Sawlani; Manoj K Singh; Payal Tripathi; Babu L Tekwani
Flow cytometric analysis of aneuploidy and S-phase fraction in chronic myeloid leukemia patients: role in early detection of accelerated phase.
Leukemia research 2003;27(10):899-902.
2003: Mitchell A Avery; Kannoth M Muraleedharan; Prashant V Desai; Achintya K Bandyopadhyaya; Marise M Furtado; Babu L Tekwani
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
Journal of medicinal chemistry 2003;46(20):4244-58.
2003: Ilias Muhammad; D Chuck Dunbar; Shabana I Khan; Babu L Tekwani; Erdal Bedir; Satoshi Takamatsu; Daneel Ferreira; Larry Walker
Antiparasitic alkaloids from Psychotria klugii.
Journal of natural products 2003;66(7):962-7.
2003: Karumanchi V Rao; Bernard D Santarsiero; Andrew D Mesecar; Ray F Schinazi; Babu L Tekwani; Mark T Hamann
New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.
Journal of natural products 2003;66(6):823-8.
2003: Ilias Muhammad; Xing-Cong Li; Melissa R Jacob; Babu L Tekwani; D Chuck Dunbar; Daneel Ferreira
Antimicrobial and antiparasitic (+)-trans-hexahydrodibenzopyrans and analogues from Machaerium multiflorum.
Journal of natural products 2003;66(6):804-9.
2003: Héctor Villa; Ana R Otero Marcos; Rosa M Reguera; Rafael Balaña-Fouce; Carlos García-Estrada; Yolanda Pérez-Pertejo; Babu L Tekwani; Peter J Myler; Kenneth D Stuart; Mary-Ann Bjornsti; David Ordóñez
A novel active DNA topoisomerase I in Leishmania donovani.
The Journal of biological chemistry 2003;278(6):3521-6.
2002: Rashmi Agrawal; Renu Tripathi; Babu L Tekwani; S K Jain; Guru P Dutta; Onkar P Shukla
Haem polymerase as a novel target of antimalarial action of cyproheptadine.
Biochemical pharmacology 2002;64(9):1399-406.
2002: Patricia C Lima; Mitchell A Avery; Babu L Tekwani; Helio M de Alves; Eliezer J Barreiro; Carlos A M Fraga
Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues.
Farmaco (Società chimica italiana : 1989) 2002;57(10):825-32.
2002: Anil K Tripathi; Rupesh Chaturvedi; Rizwan Ahmad; Mohammad Asim; Kamal K Sawlani; R L SINGH; Babu L Tekwani
Peripheral blood leucocytes ornithine decarboxylase activity in chronic myeloid leukemia patients: prognostic and therapeutic implications.
Leukemia research 2002;26(4):349-54.
2002: abhai Tripathi; Satyendra K Garg; Babu L Tekwani
A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite.
Biochemical and biophysical research communications 2002;290(1):595-601.
2001: abhai Tripathi; A Gupta; S K Garg; Babu L Tekwani
In vitro beta-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: comparative inhibition with quinoline and endoperoxide antimalarials.
Life sciences 2001;69(23):2725-33.
1999: Amit V Pandey; Babu L Tekwani; R L SINGH; Virander S Chauhan
Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite.
The Journal of biological chemistry 1999;274(27):19383-8.
1999: Amit V Pandey; N Singh; Babu L Tekwani; SUNIL KUMAR PURI; Virander S Chauhan
Assay of beta-hematin formation by malaria parasite.
Journal of pharmaceutical and biomedical analysis 1999;20(1-2):203-7.
1999: Babu L Tekwani; R K Mehlotra
Molecular basis of defence against oxidative stress in Entamoeba histolytica and Giardia lamblia.
Microbes and infection / Institut Pasteur 1999;1(5):385-94.
1999: Amit V Pandey; SK Joshi; Babu L Tekwani; Virander S Chauhan
A colorimetric assay for heme in biological samples using 96-well plates.
Analytical biochemistry 1999;268(1):159-61.
1999: Rosa M Reguera; Yolanda Pérez-Pertejo; César Ordóñez; Juan C Cubría; Babu L Tekwani; Rafael Balaña-Fouce; David Ordóñez
S-adenosylmethionine synthesis in Leishmania infantum promastigotes.
Cell biology international 1999;23(8):579-83.
1999: Juan C Cubría; César Ordóñez; Rosa M Reguera; Babu L Tekwani; Rafael Balaña-Fouce; David Ordóñez
Early alterations of polyamine metabolism induced after acute administration of clenbuterol in mouse heart.
Life sciences 1999;64(19):1739-52.
1997: Amit V Pandey; Ratan Mani Joshi; Babu L Tekwani; R L SINGH; Virander S Chauhan
Synthetic peptides corresponding to a repetitive sequence of malarial histidine rich protein bind haem and inhibit haemozoin formation in vitro.
Molecular and biochemical parasitology 1997;90(1):281-7.
1997: M Mishra; S Chandra; VC Pandey; Babu L Tekwani
Polyamine metabolism in various tissues during pathogenesis of chloroquine-susceptible and resistant malaria.
Cell biochemistry and function 1997;15(4):229-35.
1997: Amit V Pandey; Babu L Tekwani
Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials.
FEBS letters 1997;402(2-3):236-40.
1997: M Kandpal; Babu L Tekwani
Polyamine transport systems of Leishmania donovani promastigotes.
Life sciences 1997;60(20):1793-801.
1996: Amit V Pandey; Babu L Tekwani
Formation of haemozoin/beta-haematin under physiological conditions is not spontaneous.
FEBS letters 1996;393(2-3):189-93.
1996: Amit V Pandey; Babu L Tekwani
Identification and quantification of haemozoin: Some additional facts.
Parasitology today (Personal ed.) 1996;12(9):370; author reply 370.
1996: M Kandpal; Babu L Tekwani; Prem M S Chauhan; Amiya P Bhaduri
Correlation between inhibition of growth and arginine transport of Leishmania donovani promastigotes in vitro by diamidines.
Life sciences 1996;59(7):PL75-80.
1995: Babu L Tekwani; M Mishra; RK Chatterjee
Polyamine uptake by a rodent filariid, Acanthocheilonema viteae (Nematoda: Filarioidea).
The international journal of biochemistry & cell biology 1995;27(8):851-5.
1995: M Kandpal; R B Fouce; A Pal; P Y Guru; Babu L Tekwani
Kinetics and molecular characteristics of arginine transport by Leishmania donovani promastigotes.
Molecular and biochemical parasitology 1995;71(2):193-201.
1992: Anu Agarwal; O P Shukla; Babu L Tekwani
Characterization of Ca(2+)-ATPase of Setaria cervi (Nematoda: Filarioidea): effect of phenothiazines and anthelmintics.
The International journal of biochemistry 1992;24(9):1447-52.
1992: S Mukerjee; R K Upreti; Babu L Tekwani; A M Kidwai
Biochemical analysis of jejunal brush border membrane of golden hamster: pathogenic modulations due to ancylostomiasis.
Indian journal of biochemistry & biophysics 1992;29(1):82-6.
1992: Babu L Tekwani
Secretory cholinesterase of Ancylostoma ceylanicum: effect of tubulin binding agents and benzimidazole anthelmintics.
Life sciences 1992;50(10):747-52.
1991: S K Sahni; N Saxena; Babu L Tekwani; Guru P Dutta; VC Pandey
Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice.
Experimental and molecular pathology 1991;55(1):55-62.
1991: R Dhawan; Umesh C Chaturvedi; M Khanna; A Mathur; Babu L Tekwani; VC Pandey; R N Rai
Obligatory role of Ca2+ in the cytotoxic activity of dengue virus-induced cytotoxin.
International journal of experimental pathology 1991;72(1):31-9.
1991: M Khanna; Umesh C Chaturvedi; R Dhawan; Babu L Tekwani; VC Pandey
Presence of Ca2+ is obligatory for the cytotoxic activity of dengue virus-induced cytotoxic factor.
Immunology 1991;72(1):73-8.
1991: V Sharma; Babu L Tekwani; J K Saxena; Suman Gupta; JC Katiyar; RK Chatterjee; S Ghatak; O P Shukla
Polyamine metabolism in some helminth parasites.
Experimental parasitology 1991;72(1):15-23.
1990: Anu Agarwal; O P Shukla; S Ghatak; Babu L Tekwani
Biogenic amines, metabolites and monoamine oxidase in the filarial worm Setaria cervi.
International journal for parasitology 1990;20(7):873-81.
1990: Babu L Tekwani; LM Tripathi; S Mukerjee; Suman Gupta; VC Pandey; JC Katiyar; S Ghatak; O P Shukla
Hepatic microsomal cytochrome P450 system during experimental hookworm infection.
Experimental and molecular pathology 1990;52(3):330-9.
1990: S Mukerjee; Ramesh Chander; Babu L Tekwani; Suman Gupta; JC Katiyar; O P Shukla; N K Kapoor
Molecular basis of hyperlipidemia in golden hamsters during experimental infection with Ancylostoma ceylanicum (Nematoda:Strongylidae).
International journal for parasitology 1990;20(2):217-23.
1990: Anu Agarwal; Babu L Tekwani; O P Shukla; S Ghatak
Effect of anthelmintics and phenothiazines on adenosine 5'-triphosphatases of filarial parasite Setaria cervi.
Indian journal of experimental biology 1990;28(3):245-8.
1989: A K Singh; Babu L Tekwani; P Y Guru; AK Rastogi; VC Pandey
Suppression of the hepatic microsomal cytochrome P-450 dependent mixed function oxidase activities in golden hamster during Leishmania donovani infection.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21(5):507-12.
1988: Babu L Tekwani; LM Tripathi; O P Shukla; S Ghatak
Suppression of release of microfilariae in vitro from Setaria cervi (Nematoda: Filariodeae) by chlorpromazine.
The Journal of parasitology 1988;74(5):893-5.
1988: S Mukerjee; Babu L Tekwani; LM Tripathi; S C Maitra; PK Visen; JC Katiyar; S Ghatak
Biochemical and histopathological alterations in golden hamster during infection with Ancylostoma ceylanicum.
Experimental and molecular pathology 1988;49(1):50-61.
1988: LM Tripathi; Babu L Tekwani; S Mukerjee; A Agarwal; A Misra; VC Pandey; JC Katiyar; S Ghatak
Hydrolytic enzymes during pathogenesis of Nippostrongylus brasiliensis infection in rats.
The Indian journal of medical research 1988;87():225-8.
1988: Babu L Tekwani; LM Tripathi; S Mukerjee; PK Visen; JC Katiyar; O P Shukla; S Ghatak
Status of the microsomal mixed function oxidase system in the intestine, lungs and kidneys of hamsters during infection with Ancylostoma ceylanicum.
International journal for parasitology 1988;18(1):11-4.
1987: Babu L Tekwani; LM Tripathi; S Ghatak
Biochemical changes in mitochondria of mouse brain during experimental infection with Acanthamoeba culbertsoni (strain-A-1).
Indian journal of experimental biology 1987;25(6):408-11.
1987: Babu L Tekwani; LM Tripathi; S Mukerjee; A Mishra; O P Shukla; S Ghatak
Impairment of the hepatic microsomal drug-metabolizing system in rats parasitized with Nippostrongylus brasiliensis.
Biochemical pharmacology 1987;36(8):1383-6.
1985: LM Tripathi; Babu L Tekwani; R Sen; S Ghatak
Effect of anticonvulsants, centazolone and centpropazine, on gamma amino butyric acid metabolism in mouse brain.
Indian journal of experimental biology 1985;23(8):452-5.
1985: Babu L Tekwani; LM Tripathi; S Ghatak
Status of mouse brain gamma aminobutyric acid metabolism during experimental primary amoebic meningoencephalitis.
The Indian journal of medical research 1985;82():183-7.
1985: Babu L Tekwani; R D Rai; LM Tripathi; S Ghatak
Mouse brain carbohydrate and energy metabolism during experimental primary amoebic meningoencephalitis.
Indian journal of experimental biology 1985;23(7):397-401.
1984: Babu L Tekwani; LM Tripathi; V K Mohan Rao
Biochemical changes in mouse brain myelin during experimental primary amoebic meningo-encephalitis.
British journal of experimental pathology 1984;65(5):637-44.
1983: R D Rai; Babu L Tekwani; V K Mohan Rao
Enzymatic changes in experimental primary amoebic meningoencephalitis.
The Indian journal of medical research 1983;77():194-200.
1982: Babu L Tekwani; LM Tripathi; V K Mohan Rao
Changes in levels of monoamines during experimental primary amoebic meningoencephalitis.
Indian journal of experimental biology 1982;20(1):52-5.