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Herman Ten Brink

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Cátia C P Aires; Graça Soveral; Paula B M Luís; Herman J Ten Brink; Isabel Tavares de Almeida; Marinus Duran; Ronald J A Wanders; Margarida F B Silva
Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes.
Cátia C P Aires; Jos P N Ruiter; Paula B M Luís; Herman J Ten Brink; Lodewijk IJlst; Isabel Tavares de Almeida; Marinus Duran; Ronald J A Wanders; Margarida F B Silva
Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acids.
Sven W Sauer; Stefan Kölker; Georg F Hoffmann; Herman J Ten Brink; Cornelis Jakobs; K Michael Gibson; Jürgen G Okun
Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice).

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2008: Cátia C P Aires; Graça Soveral; Paula B M Luís; Herman J Ten Brink; Isabel Tavares de Almeida; Marinus Duran; Ronald J A Wanders; Margarida F B Silva
Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes.
FEBS letters 2008;582(23-24):3359-66.
2007: Cátia C P Aires; Jos P N Ruiter; Paula B M Luís; Herman J Ten Brink; Lodewijk IJlst; Isabel Tavares de Almeida; Marinus Duran; Ronald J A Wanders; Margarida F B Silva
Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acids.
Biochimica et biophysica acta 2007;1771(4):533-43.
2007: Sven W Sauer; Stefan Kölker; Georg F Hoffmann; Herman J Ten Brink; Cornelis Jakobs; K Michael Gibson; Jürgen G Okun
Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice).
Neurochemistry international 2007;50(4):653-9.
2006: Eduard A Struys; Nanda M Verhoeven; Erwin E W Jansen; Herman J Ten Brink; Maneesh Gupta; Terry Burlingame; Lawrence S Quang; Timothy J Maher; Piero Rinaldo; O Carter Snead; Amy K Goodwin; Elise M Weerts; P Rand Brown; Tonya C Murphy; Matthew J Picklo; Cornelius Jakobs; K Michael Gibson
Metabolism of gamma-hydroxybutyrate to d-2-hydroxyglutarate in mammals: further evidence for d-2-hydroxyglutarate transhydrogenase.
Metabolism: clinical and experimental 2006;55(3):353-8.
2005: H Gan-Schreier; Jürgen G Okun; D Kohlmueller; C-D Langhans; V Peters; Herman J Ten Brink; Nanda M Verhoeven; Cornelis Jakobs; A Voelkl; Georg F Hoffmann
Measurement of bile acid CoA esters by high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry (HPLC-ESI-MS/MS).
Journal of mass spectrometry : JMS 2005;40(7):882-9.
2005: Eduard A Struys; Nanda M Verhoeven; Herman J Ten Brink; W V Wickenhagen; K Michael Gibson; Cornelis Jakobs
Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias.
Journal of inherited metabolic disease 2005;28(6):921-30.
2004: Tom Teerlink; Rob Barto; Herman J Ten Brink; Casper G Schalkwijk
Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry.
Clinical chemistry 2004;50(7):1222-8.
2002: D S M Schor; Nanda M Verhoeven; Eduard A Struys; Herman J Ten Brink; Cornelis Jakobs
Quantification of 3-hydroxyglutaric acid in urine, plasma, cerebrospinal fluid and amniotic fluid by stable-isotope dilution negative chemical ionization gas chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;780(1):199-204.
2001: Margarida F B Silva; Jos P N Ruiter; Lodewijk IJlst; Paul Allers; Herman J Ten Brink; Cornelis Jakobs; Marinus Duran; Isabel Tavares de Almeida; Ronald J A Wanders
Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites.
Analytical biochemistry 2001;290(1):60-7.
2000: CG Costa; WS Guérand; Eduard A Struys; U Holwerda; Herman J Ten Brink; Isabel Tavares de Almeida; Marinus Duran; Cornelis Jakobs
Quantitative analysis of urinary acylglycines for the diagnosis of beta-oxidation defects using GC-NCI-MS.
Journal of pharmaceutical and biomedical analysis 2000;21(6):1215-24.
1999: Gerbert Jansen; Nanda M Verhoeven; Simone Denis; G Romeijn; Cornelis Jakobs; Herman J Ten Brink; Ronald J A Wanders
Phytanic acid alpha-oxidation: identification of 2-hydroxyphytanoyl-CoA lyase in rat liver and its localisation in peroxisomes.
Biochimica et biophysica acta 1999;1440(2-3):176-82.
1999: Eduard A Struys; WS Guérand; Herman J Ten Brink; Cornelis Jakobs
Combined method for the determination of gamma-aminobutyric and beta-alanine in cerebrospinal fluid by stable isotope dilution mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(1):245-9.
1999: Casper G Schalkwijk; N Posthuma; Herman J Ten Brink; Piet M ter Wee; Tom Teerlink
Induction of 1,2-dicarbonyl compounds, intermediates in the formation of advanced glycation end-products, during heat-sterilization of glucose-based peritoneal dialysis fluids.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1999;19(4):325-33.
1998: Eduard A Struys; Erwin E W Jansen; Herman J Ten Brink; Nanda M Verhoeven; M S van der Knaap; Cornelis Jakobs
An accurate stable isotope dilution gas chromatographic-mass spectrometric approach to the diagnosis of guanidinoacetate methyltransferase deficiency.
Journal of pharmaceutical and biomedical analysis 1998;18(4-5):659-65.
1998: Nanda M Verhoeven; Cornelis Jakobs; Herman J Ten Brink; RJ Wanders; Charles R Roe
Studies on the oxidation of phytanic acid and pristanic acid in human fibroblasts by acylcarnitine analysis.
Journal of inherited metabolic disease 1998;21(7):753-60.
1997: Ronald J A Wanders; L Vilarinho; H P Hartung; Georg F Hoffmann; P A Mooijer; Gerbert Jansen; Jan G M Huijmans; J B C de Klerk; Herman J Ten Brink; Cornelis Jakobs; Marinus Duran
L-2-Hydroxyglutaric aciduria: normal L-2-hydroxyglutarate dehydrogenase activity in liver from two new patients.
Journal of inherited metabolic disease 1997;20(5):725-6.
1997: Nanda M Verhoeven; D S M Schor; Herman J Ten Brink; RJ Wanders; Cornelis Jakobs
Resolution of the phytanic acid alpha-oxidation pathway: identification of pristanal as product of the decarboxylation of 2-hydroxyphytanoyl-CoA.
Biochemical and biophysical research communications 1997;237(1):33-6.
1997: Nanda M Verhoeven; D S M Schor; Gerbert Jansen; R M Kok; Herman J Ten Brink; RJ Wanders; Cornelis Jakobs
Formation of 2,3-pristenic acid and 3-hydroxypristanic acid from pristanic acid in human liver.
Journal of inherited metabolic disease 1997;20(3):441-3.
1997: CG Costa; Eduard A Struys; Albert H Bootsma; Herman J Ten Brink; L Dorland; Isabel Tavares de Almeida; Marinus Duran; Cornelis Jakobs
Quantitative analysis of plasma acylcarnitines using gas chromatography chemical ionization mass fragmentography.
Journal of lipid research 1997;38(1):173-82.
1995: R J Wanders; Carlo W T van Roermund; D S M Schor; Herman J Ten Brink; C Jakobs
Phytanic acid oxidation in man: identification of a new enzyme catalysing the formation of 2-ketophytanic acid from 2-hydroxyphytanic acid and its deficiency in the Zellweger syndrome.
Journal of inherited metabolic disease 1995;18(2):201-3.
1994: R J Wanders; Carlo W T van Roermund; D S M Schor; Herman J Ten Brink; C Jakobs
2-Hydroxyphytanic acid oxidase activity in rat and human liver and its deficiency in the Zellweger syndrome.
Biochimica et biophysica acta 1994;1227(3):177-82.
1994: Herman J Ten Brink; R J Wanders; E Christensen; N J Brandt; C Jakobs
Heterogeneity in di/trihydroxycholestanoic acidaemia.
Annals of clinical biochemistry 1994;31 ( Pt 2)():195-7.
1993: Herman J Ten Brink; C M van den Heuvel; E Christensen; C Largillière; C Jakobs
Diagnosis of peroxisomal disorders by analysis of phytanic and pristanic acids in stored blood spots collected at neonatal screening.
Clinical chemistry 1993;39(9):1904-6.
1993: K M Gibson; Herman J Ten Brink; D S M Schor; R M Kok; A H Bootsma; G F Hoffmann; C Jakobs
Stable-isotope dilution analysis of D- and L-2-hydroxyglutaric acid: application to the detection and prenatal diagnosis of D- and L-2-hydroxyglutaric acidemias.
Pediatric research 1993;34(3):277-80.
1993: Herman J Ten Brink; C M van den Heuvel; Bwee Tien Poll-The; R J Wanders; C Jakobs
Peroxisomal disorders: concentrations of metabolites in cerebrospinal fluid compared with plasma.
Journal of inherited metabolic disease 1993;16(3):587-90.
1992: Herman J Ten Brink; D S M Schor; R M Kok; F Stellaard; J Kneer; Bwee Tien Poll-The; J M Saudubray; C Jakobs
In vivo study of phytanic acid alpha-oxidation in classic Refsum's disease and chondrodysplasia punctata.
Pediatric research 1992;32(5):566-70.
1992: Herman J Ten Brink; D S M Schor; R M Kok; Bwee Tien Poll-The; R J Wanders; C Jakobs
Phytanic acid alpha-oxidation: accumulation of 2-hydroxyphytanic acid and absence of 2-oxophytanic acid in plasma from patients with peroxisomal disorders.
Journal of lipid research 1992;33(10):1449-57.
1992: R J Wanders; Simone Denis; Carlo W T van Roermund; C Jakobs; Herman J Ten Brink
Characteristics and subcellular localization of pristanoyl-CoA synthetase in rat liver.
Biochimica et biophysica acta 1992;1125(3):274-9.
1992: R J Wanders; Simone Denis; C Jakobs; Herman J Ten Brink
Identification of pristanoyl-CoA oxidase as a distinct, clofibrate non-inducible enzyme in rat liver peroxisomes.
Biochimica et biophysica acta 1992;1124(2):199-202.
1992: R J Wanders; Simone Denis; C Jakobs; Herman J Ten Brink
Activation and oxidation of pristanic acid in rat liver: identification of a distinct, clofibrate non-inducible pristanoyl-CoA oxidase.
Progress in clinical and biological research 1992;375():245-52.
1992: Herman J Ten Brink; F Stellaard; C M van den Heuvel; R M Kok; D S M Schor; R J Wanders; C Jakobs
Pristanic acid and phytanic acid in plasma from patients with peroxisomal disorders: stable isotope dilution analysis with electron capture negative ion mass fragmentography.
Journal of lipid research 1992;33(1):41-7.
1991: Herman J Ten Brink; Bwee Tien Poll-The; J M Saudubray; R J Wanders; C Jakobs
Pristanic acid does not accumulate in peroxisomal acyl-CoA oxidase deficiency: evidence for a distinct peroxisomal pristanyl-CoA oxidase.
Journal of inherited metabolic disease 1991;14(5):681-4.
1991: C Jakobs; Herman J Ten Brink; S A Langelaar; T Zee; F Stellaard; Milan Macek Jr.; K Srsnová; S Srsen; W J Kleijer
Stable isotope dilution analysis of N-acetylaspartic acid in CSF, blood, urine and amniotic fluid: accurate postnatal diagnosis and the potential for prenatal diagnosis of Canavan disease.
Journal of inherited metabolic disease 1991;14(5):653-60.
1991: R J Wanders; Carlo W T van Roermund; C Jakobs; Herman J Ten Brink
Identification of pristanoyl-CoA oxidase and phytanic acid decarboxylation in peroxisomes and mitochondria from human liver: implications for Zellweger syndrome.
Journal of inherited metabolic disease 1991;14(3):349-52.
1991: Herman J Ten Brink; R J Wanders; F Stellaard; R B Schutgens; C Jakobs
Pristanic acid and phytanic acid in plasma from patients with a single peroxisomal enzyme deficiency.
Journal of inherited metabolic disease 1991;14(3):345-8.
1990: F Stellaard; Herman J Ten Brink; R M Kok; L van den Heuvel; C Jakobs
Stable isotope dilution analysis of very long chain fatty acids in plasma, urine and amniotic fluid by electron capture negative ion mass fragmentography.
Clinica chimica acta; international journal of clinical chemistry 1990;192(2):133-44.
1990: R J Wanders; Herman J Ten Brink; Carlo W T van Roermund; R B Schutgens; J M Tager; C Jakobs
Identification of pristanoyl-CoA oxidase activity in human liver and its deficiency in the Zellweger syndrome.
Biochemical and biophysical research communications 1990;172(2):490-5.
1990: C Jakobs; Herman J Ten Brink; F Stellaard
Prenatal diagnosis of inherited metabolic disorders by quantitation of characteristic metabolites in amniotic fluid: facts and future.
Prenatal diagnosis 1990;10(4):265-71.
1989: C Jakobs; Herman J Ten Brink; R M Kok; F Stellaard; W J Kleijer; R J Wanders; R B Schutgens
Very long fatty acids in amniotic fluid from a fetus affected with Zellweger syndrome.
European journal of pediatrics 1989;148(6):581.