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Yik-Ying Teo

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Lai-Ping Wong; Dorothy S-L Toh; Sze-Ling Chan; Kee-Seng Chia; Wan-Ting Poh; Cynthia Sung; Liesbet L Tan; Yik-Ying Teo
Singapore Pharmacogenomics Portal: a web resource for evaluating human genetic variations of genes responsible for drug responses.
Xu Wang; Tien Yin Wong; Weihua Zhang; Tin Aung; John C Chambers; Peng Chen; Ching-Yu Cheng; Kee-Seng Chia; Hui-Xiang Chua; Norihiro Kato; Chiea-Chuen Khor; Jaspal S Kooner; Jianjun Liu; Xuanyao Liu; Rick Twee-Hee Ong; Xueling Sim; Chen Suo; E Shyong Tai; Fumihiko Takeuchi; Wan-Ting Tay; Yik-Ying Teo
Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies.
Xuebin Zheng; Jin-Xin Bei; Siow-Ann Chong; Jia Nee Foo; Ishak D Irwan; Jimmy Lee; Herty Liany; Tian Liu; Tai E Shyong; Kang Sim; Yik-Ying Teo; Haiyan Xu; Jianjun Liu
The association between rare large duplication of 16p11.2 and schizophrenia in the Singaporean Chinese population.

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All Publications

2013: Lai-Ping Wong; Dorothy S-L Toh; Sze-Ling Chan; Kee-Seng Chia; Wan-Ting Poh; Cynthia Sung; Liesbet L Tan; Yik-Ying Teo
Singapore Pharmacogenomics Portal: a web resource for evaluating human genetic variations of genes responsible for drug responses.
Pharmacogenetics and genomics 2013;23(6):329-32.
2013: Xu Wang; Tien Yin Wong; Weihua Zhang; Tin Aung; John C Chambers; Peng Chen; Ching-Yu Cheng; Kee-Seng Chia; Hui-Xiang Chua; Norihiro Kato; Chiea-Chuen Khor; Jaspal S Kooner; Jianjun Liu; Xuanyao Liu; Rick Twee-Hee Ong; Xueling Sim; Chen Suo; E Shyong Tai; Fumihiko Takeuchi; Wan-Ting Tay; Yik-Ying Teo
Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies.
Human molecular genetics 2013;22(11):2303-11.
2013: Xuebin Zheng; Jin-Xin Bei; Siow-Ann Chong; Jia Nee Foo; Ishak D Irwan; Jimmy Lee; Herty Liany; Tian Liu; Tai E Shyong; Kang Sim; Yik-Ying Teo; Haiyan Xu; Jianjun Liu
The association between rare large duplication of 16p11.2 and schizophrenia in the Singaporean Chinese population.
Schizophrenia research 2013;146(1-3):368-9.
2013: Lai-Ping Wong; Tien Yin Wong; Haiyan Xu; Eric P H Yap; Sharon Wee; Markus Rene Wenk; Tin Aung; Peng Chen; Ching-Yu Cheng; Kee-Seng Chia; Jia-Nee Foo; Linda S H Gan; Chiea C Khor; Seok Hwee Koo; Kevin Koi-Yau Lam; Ruoying Li; Wei-Yen Lim; Yenly Lim; Peter Little; Xuanyao Liu; Pauline Crystal Ng; Rick Twee-Hee Ong; Nisha Esakimuthu Pillai; Wee-Teng Poh; KS Sim; Ngak-Leng Sim; Richie Soong; Linda Wei-Lin Tan; Shu-Mei Teo; Yik-Ying Teo
Deep whole-genome sequencing of 100 southeast Asian Malays.
American journal of human genetics 2013;92(1):52-66.
2012: Rick Twee-Hee Ong; Xu Wang; Xuanyao Liu; Yik-Ying Teo
Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping.
European journal of human genetics : EJHG 2012;20(12):1300-7.
2012: Sze Ling Chan; Kee-Seng Chia; Chen Suo; Yik-Ying Teo
The population attributable fraction as a measure of the impact of warfarin pharmacogenetic testing.
Pharmacogenomics 2012;13(11):1247-56.
2012: Xu Wang; Tien Yin Wong; Haiyan Xu; Tin Aung; Kee-Seng Chia; Chiea C Khor; Jianjun Liu; Xuanyao Liu; Daniel P K Ng; Rick Twee-Hee Ong; Wee-Teng Poh; Xueling Sim; Chen Suo; E Shyong Tai; Wan-Ting Tay; Yik-Ying Teo
A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations.
European journal of human genetics : EJHG 2012;20(4):469-75.
2012: Lai Fun Thean; Jian-Min Yuan; Poh-Koon Koh; Woon-Puay Koh; Hui Hua Li; Choong-Leong Tang; Yik-Ying Teo; Mei-Lin Teoh; Peh Yean Cheah
Association of Caucasian-identified variants with colorectal cancer risk in Singapore Chinese.
PloS one 2012;7(8):e42407.
2012: Qiao Fan; Liang-Kee Goh; Felicia Hawthorne; Candice E H Ho; Hidetoshi Inoko; Chiea C Khor; Yi-Ju Li; Wan'e Lim; Fumihiko Matsuda; Keitaro Matsuo; Akira Meguro; Nobuhisa Mizuki; Isao Nakata; Kyoko Ohno-Matsui; Mark Seielstad; E Shyong Tai; Yik-Ying Teo; Eranga N Vithana; Tien Yin Wong; Kenji Yamashiro; Nagahisa Yoshimura; Terri L Young; Yingfeng Zheng; Xin Zhou; Tin Aung; Veluchamy A Barathi; Roger W Beuerman; Ching-Yu Cheng; Daniel Chua; Seang-Mei Saw
Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.
PLoS genetics 2012;8(6):e1002753.
2012: Yik-Ying Teo
Genotype calling for the Illumina platform.
Methods in molecular biology (Clifton, N.J.) 2012;850():525-38.
2012: Kok Wei Lee; Yik-Ying Teo; Puay San Woon; Kang Sim
Genome wide association studies (GWAS) and copy number variation (CNV) studies of the major psychoses: what have we learnt?
Neuroscience and biobehavioral reviews 2012;36(1):556-71.
2011: Qiao Fan; Liang-Kee Goh; Mohammad Kamran Ikram; Chiea C Khor; Yi-Ju Li; Jianjun Liu; Rick Twee-Hee Ong; Mark Seielstad; Xueling Sim; Chen Suo; E Shyong Tai; Wan-Ting Tay; Yik-Ying Teo; Eranga N Vithana; Tien Yin Wong; Terri L Young; Xin Zhou; Tin Aung; Ching-Yu Cheng; Kee-Seng Chia; Belinda Cornes; Seang-Mei Saw
Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.
PLoS genetics 2011;7(12):e1002402.
2011: Haiyan Xu; Tien Yin Wong; Tin Aung; Kee-Seng Chia; Chiea C Khor; Jianjun Liu; Rick Twee-Hee Ong; Wan-Ting Poh; Mark Seielstad; Xueling Sim; Chen Suo; E Shyong Tai; Wan-Ting Tay; Yik-Ying Teo
SgD-CNV, a database for common and rare copy number variants in three Asian populations.
Human mutation 2011;32(12):1341-9.
2011: Chiea C Khor; Mai Ngoc Lanh; Le Bich Lien; Hoang Truong Long; Nguyen Minh Nguyet; Rick T H Ong; Junxiong Pang; Anavaj Sakuntabhai; Nguyen Thi Nguyet Binh; Tran Nguyen Bich Chau; Sonia Davila; Sarah J Dunstan; Jeremy Farrar; Tran Thi Gan; Martin L Hibberd; Nguyen Trong Hieu; Dennis E K Tan; Yik-Ying Teo; Nguyen Thi Hong Tham; Tran Thi Nhu Thuy; Le Trung Tri; Nguyen Minh Tuan; Nguyen Van N Vinh Chau; Ta Van Tram; Bridget Wills; Cameron P Simmons
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.
Nature genetics 2011;43(11):1139-41.
2011: Siyu Han; Chiea-Chuen Khor; Raghavan Lavanya; Jeannette Jen-Mai Lee; Jianjun Liu; Rick Twee-Hee Ong; Tin Aung; Peng Chen; Kee-Seng Chia; Qiao Fan; Liang-Kee Goh; Mark Seielstad; Xueling Sim; Chen Suo; E Shyong Tai; Wan-Ting Tay; Yik-Ying Teo; Eranga N Vithana; Tien Yin Wong; Renyi Wu; Yingfeng Zheng; Seang-Mei Saw
Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.
Human molecular genetics 2011;20(18):3693-8.
2011: Chee-Seng Ku; Nasheen Naidoo; Yudi Pawitan; Mark Seielstad; Xueling Sim; Shu-Mei Teo; Yik-Ying Teo; Kee-Seng Chia; Agus Salim
Copy number polymorphisms in new HapMap III and Singapore populations.
Journal of human genetics 2011;56(8):552-60.
2011: Mikael Hartman; Chen Suo; Wei Yen Lim; Hui Miao; Yik-Ying Teo; Kee-Seng Chia
Ability to predict breast cancer in Asian women using a polygenic susceptibility model.
Breast cancer research and treatment 2011;127(3):805-12.
2011: Chiea Chuen Khor; Wishal D Ramdas; Eranga N Vithana; Belinda K Cornes; Xueling Sim; Wan-Ting Tay; Seang-Mei Saw; Yingfeng Zheng; Raghavan Lavanya; Renyi Wu; Jie Jin Wang; Paul Mitchell; André G Uitterlinden; Fernando Rivadeneira; Yik-Ying Teo; Kee-Seng Chia; Mark Seielstad; Martin Hibberd; Johannes Vingerling; Caroline C W Klaver; Nomdo M Jansonius; E Shyong Tai; Tien Yin Wong; Cornelia M van Duijn; Tin Aung
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.
Human molecular genetics 2011;20(9):1864-72.
2011: Xueling Sim; Rick Twee-Hee Ong; Chen Suo; Wan-Ting Tay; Jianjun Liu; Daniel P K Ng; Michael Boehnke; Kee-Seng Chia; Tien Yin Wong; Mark Seielstad; Yik-Ying Teo; E Shyong Tai
Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
PLoS genetics 2011;7(4):e1001363.
2011: Rick Twee-Hee Ong; Xuanyao Liu; Wan-Ting Poh; Xueling Sim; Kee-Seng Chia; Yik-Ying Teo
A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies.
Bioinformatics (Oxford, England) 2011;27(6):822-8.
2011: Zehao Tan; Yik-Ying Teo; Eranga Vithana; Tin Aung; Chiea Chuen Khor; Chee Keong Kwoh; Jiang Liu; Sim-Heng Ong; E Shyong Tai; Zhuo Zhang; Tien Yin Wong
A hybrid framework for genome wide epistasis discovery.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2011;2011():6479-82.
2010: Eng-King Tan; C S Lu; R Peng; Yik-Ying Teo; Y H Wu-Chou; R S Chen; Y H Weng; C M Chen; H C Fung; L C Tan; Z J Zhang; X K An; G J Lee-Chen; M C Lee; Stephanie Fook-Chong; Jean-Marc Burgunder; Ruey-Meei Wu; Y R Wu
Analysis of the UCHL1 genetic variant in Parkinson's disease among Chinese.
Neurobiology of aging 2010;31(12):2194-6.
2010: Yik-Ying Teo; Rick T H Ong; Xueling Sim; E Shyong Tai; Kee-Seng Chia
Identifying candidate causal variants via trans-population fine-mapping.
Genetic epidemiology 2010;34(7):653-64.
2010: Jieming Chen; Yik-Ying Teo; Dorothy S L Toh; Cynthia Sung
Interethnic comparisons of important pharmacology genes using SNP databases: potential application to drug regulatory assessments.
Pharmacogenomics 2010;11(8):1077-94.
2010: Chee-Seng Ku; Yudi Pawitan; Xueling Sim; Rick T H Ong; Mark Seielstad; Edmund J D Lee; Yik-Ying Teo; Kee-Seng Chia; Agus Salim
Genomic copy number variations in three Southeast Asian populations.
Human mutation 2010;31(7):851-7.
2010: Rick Twee-Hee Ong; Yik-Ying Teo
varLD: a program for quantifying variation in linkage disequilibrium patterns between populations.
Bioinformatics (Oxford, England) 2010;26(9):1269-70.
2010: Eng-King Tan; Rong Peng; Yik-Ying Teo; Louis C Tan; Dario Angeles; Patrick Ho; Meng-Ling Chen; Chin-Hsien Lin; Xue-Ye Mao; Xue-Li Chang; Kumar M Prakash; Jian-Jun Liu; Wing Lok Au; Wei-Dong Le; Joseph Jankovic; Jean-Marc Burgunder; Yi Zhao; Ruey-Meei Wu
Multiple LRRK2 variants modulate risk of Parkinson disease: a Chinese multicenter study.
Human mutation 2010;31(5):561-8.
2010: Yik-Ying Teo; Xueling Sim
Patterns of linkage disequilibrium in different populations: implications and opportunities for lipid-associated loci identified from genome-wide association studies.
Current opinion in lipidology 2010;21(2):104-15.
2010: Yik-Ying Teo; Kerrin S Small; Dominic P Kwiatkowski
Methodological challenges of genome-wide association analysis in Africa.
Nature reviews. Genetics 2010;11(2):149-60.
2010: Yoon-Dong Yu; Yoonjoo Choi; Yik-Ying Teo; Andrew R Dalby
Developing stochastic models for spatial inference: bacterial chemotaxis.
PloS one 2010;5(5):e10464.
2009: Yik-Ying Teo; Xueling Sim; Rick T H Ong; Adrian K S Tan; Jieming Chen; Erwin Tantoso; Kerrin S Small; Chee-Seng Ku; Edmund J D Lee; Mark Seielstad; Kee-Seng Chia
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations.
Genome research 2009;19(11):2154-62.
2009: Eng-King Tan; Yik-Ying Teo; Kumar M Prakash; R Li; H-Q Lim; D Angeles; L-C Tan; W-L Au; Yuan Yih; Yi Zhao
LINGO1 variant increases risk of familial essential tremor.
Neurology 2009;73(14):1161-2.
2009: Eng-King Tan; Jeannette Lee; Christopher P L-H Chen; Yik-Ying Teo; Yi Zhao; W L Lee
SORL1 haplotypes modulate risk of Alzheimer's disease in Chinese.
Neurobiology of aging 2009;30(7):1048-51.
2009: Ene-Choo Tan; Eileen C P Lim; Yik-Ying Teo; Yvonne Lim; Hai-Yang Law; Alex T Sia
Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain.
Molecular pain 2009;5():32.
2008: Alex T Sia; Yvonne Lim; Eileen C P Lim; Rachelle W C Goh; Hai Yang Law; Ruth Landau; Yik-Ying Teo; Ene-Choo Tan
A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia.
Anesthesiology 2008;109(3):520-6.
2008: Ene-Choo Tan; Yvonne Lim; Yik-Ying Teo; Rachelle Goh; Hai-Yang Law; Alex T Sia
Ethnic differences in pain perception and patient-controlled analgesia usage for postoperative pain.
The journal of pain : official journal of the American Pain Society 2008;9(9):849-55.
2007: Eng-King Tan; Eva Chua; Stephanie Fook-Chong; Yik-Ying Teo; Yih Yuen; Louis Tan ; Yi Zhao
Association between caffeine intake and risk of Parkinson's disease among fast and slow metabolizers.
Pharmacogenetics and genomics 2007;17(11):1001-5.
2006: Eng-King Tan; Z Y Lu; Stephanie Fook-Chong; E Tan; Hui Shen; Eva Chua; Yuan Yih; Yik-Ying Teo; Yi Zhao
Exploring an interaction of adenosine A2A receptor variability with coffee and tea intake in Parkinson's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(6):634-6.
2006: Yong-Hao Pua; Michael Teik-Hin Koh; Yik-Ying Teo
Effects of allometric scaling and isokinetic testing methods on the relationship between countermovement jump and quadriceps torque and power.
Journal of sports sciences 2006;24(4):423-32.
2005: Ene-Choo Tan; Siow-Ann Chong; Hanhui Wang; Eileen Chew-Ping Lim; Yik-Ying Teo
Gender-specific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophrenia.
Brain research. Molecular brain research 2005;139(2):212-6.
2005: Eng-King Tan; Daniel Kam Yin Chan; Ping-Wing Ng; Jean Woo; Yik-Ying Teo; Kun Tang; Li-Peng Wong; Samuel S Chong; Chris Tan; Hui Shen; Yi Zhao; Caroline G L Lee
Effect of MDR1 haplotype on risk of Parkinson disease.
Archives of neurology 2005;62(3):460-4.
2004: Eng-King Tan; Marek Drozdzik; Monika Bialecka; Krystyna Honczarenko; Gabriela Klodowska-Duda; Yik-Ying Teo; Kun Tang; Li-Peng Wong; Samuel S Chong; Chris Tan; Kenneth Yew; Yi Zhao; Caroline G L Lee
Analysis of MDR1 haplotypes in Parkinson's disease in a white population.
Neuroscience letters 2004;372(3):240-4.
2004: Ene-Choo Tan; Siow-Ann Chong; Lionel C C Lim; Angelina O M Chan; Yik-Ying Teo; Chay Hoon Tan; Rathi Mahendran
Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders.
Psychiatric genetics 2004;14(4):227-31.
2004: Eng-King Tan; Anthea Chai; Yik-Ying Teo; Yi Zhao; Christopher Tan; Hui Shen; Vandana R Chandran; Mei-Lin Teoh; Yuan Yih; Ratnagopal Pavanni; Meng-Cheong Wong; Kathiravelu Puvan; Yew-Long Lo; E Yap
Alpha-synuclein haplotypes implicated in risk of Parkinson's disease.
Neurology 2004;62(1):128-31.
2003: Ene-Choo Tan; Siow-Ann Chong; Chay Hoon Tan; Yik-Ying Teo; Kaitian Peng; Rathi Mahendran
Tumor necrosis factor-alpha gene promoter polymorphisms in chronic schizophrenia.
Biological psychiatry 2003;54(11):1205-11.
2003: Ene-Choo Tan; Siow-Ann Chong; Rathi Mahendran; Chay Hoon Tan; Yik-Ying Teo
Mu opioid receptor gene polymorphism and neuroleptic-induced tardive dyskinesia in patients with schizophrenia.
Schizophrenia research 2003;65(1):61-3.
2003: Ene-Choo Tan; Siow-Ann Chong; Yik-Ying Teo; Subramaniam Mythily
No evidence of molecular heterosis at the dopamine D2 receptor gene locus for smoking in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;120B(1):40-1.