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David Teplow
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25
Selkoe, Dennis
22
Condron, Margaret
20
Haass, Christian
16
Bitan, Gal
12
Lomakin, Aleksey
11
Citron, Martin
9
Benedek, George
8
Lazo, Noel
8
Walsh, Dominic
7
Koo, Edward
7
Strobel, Gary
7
Capell, Anja
7
Bowers, Michael
6
Bernstein, Summer
6
Baumketner, Andrij
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All Publications
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2009: Noguchi Akihiko; Matsumura Satoko; Dezawa Mari; Tada Mari; Yanazawa Masako; Ito Akane; Akioka Manami; Kikuchi Satoru; Sato Michio; Ideno Shouji; Noda Munehiro; Fukunari Atsushi; Muramatsu Shin-ichi; Itokazu Yutaka; Sato Kazuki; Takahashi Hitoshi; Teplow David B; Nabeshima Yo-ichi; Kakita Akiyoshi; Imahori Kazutomo; Hoshi Minako
Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.
The Journal of biological chemistry 2009;284(47):32895-905.
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2009: Ono Kenjiro; Condron Margaret M; Teplow David B
Structure-neurotoxicity relationships of amyloid beta-protein oligomers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(35):14745-50.
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2009: Maji Samir K; Ogorzalek Loo Rachel R; Inayathullah Mohammed; Spring Sean M; Vollers Sabrina S; Condron Margaret M; Bitan Gal; Loo Joseph A; Teplow David B
Amino acid position-specific contributions to amyloid beta-protein oligomerization.
The Journal of biological chemistry 2009;284(35):23580-91.
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2009: Murray Megan M; Bernstein Summer L; Nyugen Vy; Condron Margaret M; Teplow David B; Bowers Michael T
Amyloid beta protein: Abeta40 inhibits Abeta42 oligomerization.
Journal of the American Chemical Society 2009;131(18):6316-7.
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2009: Murray Megan M; Krone Mary Griffin; Bernstein Summer L; Baumketner Andrij; Condron Margaret M; Lazo Noel D; Teplow David B; Wyttenbach Thomas; Shea Joan-Emma; Bowers Michael T
Amyloid beta-protein: experiment and theory on the 21-30 fragment.
The journal of physical chemistry. B 2009;113(17):6041-6.
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2009: Walsh Dominic M; Thulin Eva; Minogue Aedín M; Gustavsson Niklas; Pang Eric; Teplow David B; Linse Sara
A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide.
The FEBS journal 2009;276(5):1266-81.
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2009: Zaghi Justin; Goldenson Ben; Inayathullah Mohammed; Lossinsky Albert S; Masoumi Ava; Avagyan Hripsime; Mahanian Michelle; Bernas Michael; Weinand Martin; Rosenthal Mark J; Espinosa-Jeffrey Araceli; de Vellis Jean; Teplow David B; Fiala Milan
Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy.
Acta neuropathologica 2009;117(2):111-24.
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2009: Roychaudhuri Robin; Yang Mingfeng; Hoshi Minako M; Teplow David B
Amyloid beta-protein assembly and Alzheimer disease.
The Journal of biological chemistry 2009;284(8):4749-53.
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2009: Ho Lap; Chen Ling Hong; Wang Jun; Zhao Wei; Talcott Stephen T; Ono Kenjiro; Teplow David; Humala Nelson; Cheng Alice; Percival Susan S; Ferruzzi Mario; Janle Elsa; Dickstein Dara L; Pasinetti Giulio Maria
Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration.
Journal of Alzheimer's disease : JAD 2009;16(1):59-72.
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2009: Zhao Wei; Wang Jun; Ho Lap; Ono Kenjiro; Teplow David B; Pasinetti Giulio M
Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization.
Journal of Alzheimer's disease : JAD 2009;16(1):49-57.
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2008: Yang Mingfeng; Teplow David B
Amyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differences.
Journal of molecular biology 2008;384(2):450-64.
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2008: Ono Kenjiro; Condron Margaret M; Ho Lap; Wang Jun; Zhao Wei; Pasinetti Giulio M; Teplow David B
Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity.
The Journal of biological chemistry 2008;283(47):32176-87.
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2008: Fluhrer Regina; Fukumori Akio; Martin Lucas; Grammer Gudula; Haug-Kröper Martina; Klier Bärbel; Winkler Edith; Kremmer Elisabeth; Condron Margaret M; Teplow David B; Steiner Harald; Haass Christian
Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
The Journal of biological chemistry 2008;283(44):30121-8.
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2008: Krone Mary Griffin; Baumketner Andrij; Bernstein Summer L; Wyttenbach Thomas; Lazo Noel D; Teplow David B; Bowers Michael T; Shea Joan-Emma
Effects of familial Alzheimer's disease mutations on the folding nucleation of the amyloid beta-protein.
Journal of molecular biology 2008;381(1):221-8.
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2008: Ren Yuhao; Strobel Gary A; Graff Jill C; Jutila Mark; Park Sung Gyoo; Gosh Sankar; Teplow David; Condron Margaret; Pang Eric; Hess Wilford M; Moore Emily
Colutellin A, an immunosuppressive peptide from Colletotrichum dematium.
Microbiology (Reading, England) 2008;154(Pt 7):1973-9.
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2008: Wang Jun; Ho Lap; Zhao Wei; Ono Kenjiro; Rosensweig Clark; Chen Linghong; Humala Nelson; Teplow David B; Pasinetti Giulio M
Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(25):6388-92.
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2007: Grant Marianne A; Lazo Noel D; Lomakin Aleksey; Condron Margaret M; Arai Hiromi; Yamin Ghiam; Rigby Alan C; Teplow David B
Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16522-7.
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2007: Yun Sijung; Urbanc B; Cruz L; Bitan G; Teplow D B; Stanley H E
Role of electrostatic interactions in amyloid beta-protein (A beta) oligomer formation: a discrete molecular dynamics study.
Biophysical journal 2007;92(11):4064-77.
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2007: Hori Yukiko; Hashimoto Tadafumi; Wakutani Yosuke; Urakami Katsuya; Nakashima Kenji; Condron Margaret M; Tsubuki Satoshi; Saido Takaomi C; Teplow David B; Iwatsubo Takeshi
The Tottori (D7N) and English (H6R) familial Alzheimer disease mutations accelerate Abeta fibril formation without increasing protofibril formation.
The Journal of biological chemistry 2007;282(7):4916-23.
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2006: Urbanc Brigita; Cruz Luis; Teplow David B; Stanley H Eugene
Computer simulations of Alzheimer's amyloid beta-protein folding and assembly.
Current Alzheimer research 2006;3(5):493-504.
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2006: Flint Beal M; Bossy-Wetzel Ella; Finkbeiner Steven; Fiskum Gary; Giasson Benoit; Johnson Carl; Khachaturian Zaven S; Lee Virginia M-Y; Nicholls David; Reddy Hemachandra; Reynolds Ian; Teplow David B; Thal Leon J; Trojanowski John Q; Walsh Dominic M; Wetzel Ronald; Wexler Nancy S; Young Anne B; Bain Lisa
Common threads in neurodegenerative disorders of aging.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(4):322-6.
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2006: Teplow David B; Lazo Noel D; Bitan Gal; Bernstein Summer; Wyttenbach Thomas; Bowers Michael T; Baumketner Andrij; Shea Joan-Emma; Urbanc Brigita; Cruz Luis; Borreguero Jose; Stanley H Eugene
Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach.
Accounts of chemical research 2006;39(9):635-45.
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2006: Fluhrer Regina; Grammer Gudula; Israel Lars; Condron Margaret M; Haffner Christof; Friedmann Elena; Böhland Claudia; Imhof Axel; Martoglio Bruno; Teplow David B; Haass Christian
A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
Nature cell biology 2006;8(8):894-6.
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2006: Fagan Tom; Kagan Bruce; Corbin David; Hwang Wonmuk; Glabe Charlie; Nault Larry; Lal Ratnesh; Teplow Dave; Albensi Ben; Sokolov Yuri
Alzheimer Research Forum Live Discussion: Now you see them, now you don't: The amyloid channel hypothesis.
Journal of Alzheimer's disease : JAD 2006;9(2):219-24.
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2006: Baumketner Andrij; Bernstein Summer L; Wyttenbach Thomas; Lazo Noel D; Teplow David B; Bowers Michael T; Shea Joan-Emma
Structure of the 21-30 fragment of amyloid beta-protein.
Protein science : a publication of the Protein Society 2006;15(6):1239-47.
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2006: Baumketner Andrij; Bernstein Summer L; Wyttenbach Thomas; Bitan Gal; Teplow David B; Bowers Michael T; Shea Joan-Emma
Amyloid beta-protein monomer structure: a computational and experimental study.
Protein science : a publication of the Protein Society 2006;15(3):420-8.
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2006: Castillo Uvidelio F; Strobel Gary A; Mullenberg Kirby; Condron Margaret M; Teplow David B; Folgiano Vincenzo; Gallo Monica; Ferracane Rosalia; Mannina Luisa; Viel Stepanie; Codde Marissa; Robison Richard; Porter Heide; Jensen James
Munumbicins E-4 and E-5: novel broad-spectrum antibiotics from Streptomyces NRRL 3052.
FEMS microbiology letters 2006;255(2):296-300.
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2006: Teplow David B
Preparation of amyloid beta-protein for structural and functional studies.
Methods in enzymology 2006;413():20-33.
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2006: Lomakin Aleksey; Teplow David B
Quasielastic light scattering study of amyloid beta-protein fibril formation.
Protein and peptide letters 2006;13(3):247-54.
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2005: Cruz Luis; Urbanc Brigita; Borreguero Jose M; Lazo Noel D; Teplow David B; Stanley H Eugene
Solvent and mutation effects on the nucleation of amyloid beta-protein folding.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18258-63.
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2005: Maji Samir K; Amsden Jason J; Rothschild Kenneth J; Condron Margaret M; Teplow David B
Conformational dynamics of amyloid beta-protein assembly probed using intrinsic fluorescence.
Biochemistry 2005;44(40):13365-76.
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2005: Bitan Gal; Fradinger Erica A; Spring Sean M; Teplow David B
Neurotoxic protein oligomers--what you see is not always what you get.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(2):88-95.
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2005: Lazo Noel D; Grant Marianne A; Condron Margaret C; Rigby Alan C; Teplow David B
On the nucleation of amyloid beta-protein monomer folding.
Protein science : a publication of the Protein Society 2005;14(6):1581-96.
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2005: Borreguero Jose M; Urbanc Brigita; Lazo Noel D; Buldyrev Sergey V; Teplow David B; Stanley H Eugene
Folding events in the 21-30 region of amyloid beta-protein (Abeta) studied in silico.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(17):6015-20.
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2005: Bernstein Summer L; Wyttenbach Thomas; Baumketner Andrij; Shea Joan-Emma; Bitan Gal; Teplow David B; Bowers Michael T
Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.
Journal of the American Chemical Society 2005;127(7):2075-84.
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2005: Lomakin Aleksey; Teplow David B; Benedek George B
Quasielastic light scattering for protein assembly studies.
Methods in molecular biology (Clifton, N.J.) 2005;299():153-74.
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2005: Vollers Sabrina S; Teplow David B; Bitan Gal
Determination of Peptide oligomerization state using rapid photochemical crosslinking.
Methods in molecular biology (Clifton, N.J.) 2005;299():11-8.
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2005: Bitan Gal; Teplow David B
Preparation of aggregate-free, low molecular weight amyloid-beta for assembly and toxicity assays.
Methods in molecular biology (Clifton, N.J.) 2005;299():3-9.
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2004: Urbanc B; Cruz L; Yun S; Buldyrev S V; Bitan G; Teplow D B; Stanley H E
In silico study of amyloid beta-protein folding and oligomerization.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(50):17345-50.
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2004: Bitan Gal; Teplow David B
Rapid photochemical cross-linking--a new tool for studies of metastable, amyloidogenic protein assemblies.
Accounts of chemical research 2004;37(6):357-64.
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2004: Klein W L; Stine W B; Teplow D B
Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease.
Neurobiology of aging 2004;25(5):569-80.
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2004: Ezra David; Castillo Uvidelio F; Strobel Gary A; Hess Wilford M; Porter Heidi; Jensen James B; Condron Margaret A M; Teplow David B; Sears Joseph; Maranta Michelle; Hunter Michelle; Weber Barbara; Yaver Debbie
Coronamycins, peptide antibiotics produced by a verticillate Streptomyces sp. (MSU-2110) endophytic on Monstera sp.
Microbiology (Reading, England) 2004;150(Pt 4):785-93.
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2003: Bitan Gal; Tarus Bogdan; Vollers Sabrina S; Lashuel Hilal A; Condron Margaret M; Straub John E; Teplow David B
A molecular switch in amyloid assembly: Met35 and amyloid beta-protein oligomerization.
Journal of the American Chemical Society 2003;125(50):15359-65.
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2003: Mousseau Darrell D; Chapelsky Sarah; De Crescenzo Gregory; Kirkitadze Marina D; Magoon Joanne; Inoue Sadayuki; Teplow David B; O'Connor-McCourt Maureen D
A direct interaction between transforming growth factor (TGF)-betas and amyloid-beta protein affects fibrillogenesis in a TGF-beta receptor-independent manner.
The Journal of biological chemistry 2003;278(40):38715-22.
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2003: Leissring Malcolm A; Lu Alice; Condron Margaret M; Teplow David B; Stein Ross L; Farris Wesley; Selkoe Dennis J
Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.
The Journal of biological chemistry 2003;278(39):37314-20.
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2003: Bitan Gal; Vollers Sabrina S; Teplow David B
Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization.
The Journal of biological chemistry 2003;278(37):34882-9.
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2003: Castillo Uvidelio; Harper James K; Strobel Gary A; Sears Joseph; Alesi Kara; Ford Eugene; Lin Janine; Hunter Michelle; Maranta Michelle; Ge Haiyan; Yaver Debbie; Jensen James B; Porter Heidi; Robison Richard; Millar D; Hess Wilford M; Condron Margret; Teplow David
Kakadumycins, novel antibiotics from Streptomyces sp NRRL 30566, an endophyte of Grevillea pteridifolia.
FEMS microbiology letters 2003;224(2):183-90.
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2003: Bitan Gal; Kirkitadze Marina D; Lomakin Aleksey; Vollers Sabrina S; Benedek George B; Teplow David B
Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):330-5.
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2002: Sun Banghua; Fan Wei; Balciunas Aldona; Cooper Jillian K; Bitan Gal; Steavenson Shirley; Denis Paul E; Young Yunjen; Adler Beverly; Daugherty Larry; Manoukian Raffi; Elliott Gary; Shen Wenyan; Talvenheimo Jane; Teplow David B; Haniu Mitsuru; Haldankar Raj; Wypych Jette; Ross Christopher A; Citron Martin; Richards William G
Polyglutamine repeat length-dependent proteolysis of huntingtin.
Neurobiology of disease 2002;11(1):111-22.
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2002: Fezoui Youcef; Teplow David B
Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization.
The Journal of biological chemistry 2002;277(40):36948-54.
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2002: Castillo Uvidelio F; Strobel Gary A; Ford Eugene J; Hess Wilford M; Porter Heidi; Jensen James B; Albert Heather; Robison Richard; Condron Margret A M; Teplow David B; Stevens Dennis; Yaver Debbie
Munumbicins, wide-spectrum antibiotics produced by Streptomyces NRRL 30562, endophytic on Kennedia nigriscans.
Microbiology (Reading, England) 2002;148(Pt 9):2675-85.
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2002: Kirkitadze Marina D; Bitan Gal; Teplow David B
Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies.
Journal of neuroscience research 2002;69(5):567-77.
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2002: Fluhrer Regina; Capell Anja; Westmeyer Gil; Willem Michael; Hartung Bianka; Condron Margaret M; Teplow David B; Haass Christian; Walter Jochen
A non-amyloidogenic function of BACE-2 in the secretory pathway.
Journal of neurochemistry 2002;81(5):1011-20.
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2002: Capell Anja; Meyn Liane; Fluhrer Regina; Teplow David B; Walter Jochen; Haass Christian
Apical sorting of beta-secretase limits amyloid beta-peptide production.
The Journal of biological chemistry 2002;277(7):5637-43.
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2002: Yong Winnie; Lomakin Aleksey; Kirkitadze Marina D; Teplow David B; Chen Sow-Hsin; Benedek George B
Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):150-4.
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2002: Xiang Zhongmin; Ho Lap; Yemul Shrishailam; Zhao Zhong; Qing Wein; Pompl Patrick; Kelley Kevin; Dang Anju; Qing Weiping; Teplow David; Pasinetti Giulio Maria
Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.
Gene expression 2002;10(5-6):271-8.
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2001: Kirkitadze M D; Condron M M; Teplow D B
Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis.
Journal of molecular biology 2001;312(5):1103-19.
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2001: Nilsberth C; Westlind-Danielsson A; Eckman C B; Condron M M; Axelman K; Forsell C; Stenh C; Luthman J; Teplow D B; Younkin S G; Näslund J; Lannfelt L
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.
Nature neuroscience 2001;4(9):887-93.
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2001: Sastre M; Steiner H; Fuchs K; Capell A; Multhaup G; Condron M M; Teplow D B; Haass C
Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch.
EMBO reports 2001;2(9):835-41.
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2001: Bitan G; Lomakin A; Teplow D B
Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins.
The Journal of biological chemistry 2001;276(37):35176-84.
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2001: Walsh D M; Hartley D M; Condron M M; Selkoe D J; Teplow D B
In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease.
The Biochemical journal 2001;355(Pt 3):869-77.
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2000: Fezoui Y; Hartley D M; Walsh D M; Selkoe D J; Osterhout J J; Teplow D B
A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils.
Nature structural biology 2000;7(12):1095-9.
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2000: Bennett B D; Denis P; Haniu M; Teplow D B; Kahn S; Louis J C; Citron M; Vassar R
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
The Journal of biological chemistry 2000;275(48):37712-7.
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2000: Fezoui Y; Hartley D M; Harper J D; Khurana R; Walsh D M; Condron M M; Selkoe D J; Lansbury P T; Fink A L; Teplow D B
An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2000;7(3):166-78.
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2000: Teplow D B
Cogitations on a proteocentric lexicon.
Neurobiology of aging 2000;21(4):563-4;discussion 567.
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2000: Kulic L; Walter J; Multhaup G; Teplow D B; Baumeister R; Romig H; Capell A; Steiner H; Haass C
Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5913-8.
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1999: Vassar R; Bennett B D; Babu-Khan S; Kahn S; Mendiaz E A; Denis P; Teplow D B; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski M A; Biere A L; Curran E; Burgess T; Louis J C; Collins F; Treanor J; Rogers G; Citron M
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Science (New York, N.Y.) 1999;286(5440):735-41.
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1999: Hartley D M; Walsh D M; Ye C P; Diehl T; Vasquez S; Vassilev P M; Teplow D B; Selkoe D J
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(20):8876-84.
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1999: Walsh D M; Hartley D M; Kusumoto Y; Fezoui Y; Condron M M; Lomakin A; Benedek G B; Selkoe D J; Teplow D B
Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates.
The Journal of biological chemistry 1999;274(36):25945-52.
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1999: Strobel G A; Miller R V; Martinez-Miller C; Condron M M; Teplow D B; Hess W M
Cryptocandin, a potent antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina.
Microbiology (Reading, England) 1999;145 ( Pt 8)():1919-26.
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1999: Watson D J; Selkoe D J; Teplow D B
Effects of the amyloid precursor protein Glu693-->Gln 'Dutch' mutation on the production and stability of amyloid beta-protein.
The Biochemical journal 1999;340 ( Pt 3)():703-9.
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1999: Teplow D B
Truncating the amyloid cascade hypothesis: the role of C-terminal Abeta peptides in Alzheimer's disease.
Neurobiology of aging 1999;20(1):71-3; discussion 87.
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1999: Lomakin A; Benedek G B; Teplow D B
Monitoring protein assembly using quasielastic light scattering spectroscopy.
Methods in enzymology 1999;309():429-59.
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1998: Kusumoto Y; Lomakin A; Teplow D B; Benedek G B
Temperature dependence of amyloid beta-protein fibrillization.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12277-82.
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1998: Miller C M; Miller R V; Garton-Kenny D; Redgrave B; Sears J; Condron M M; Teplow D B; Strobel G A
Ecomycins, unique antimycotics from Pseudomonas viridiflava.
Journal of applied microbiology 1998;84(6):937-44.
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1998: Teplow D B
Structural and kinetic features of amyloid beta-protein fibrillogenesis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(2):121-42.
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1998: Podlisny M B; Walsh D M; Amarante P; Ostaszewski B L; Stimson E R; Maggio J E; Teplow D B; Selkoe D J
Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.
Biochemistry 1998;37(11):3602-11.
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1997: Walsh D M; Lomakin A; Benedek G B; Condron M M; Teplow D B
Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.
The Journal of biological chemistry 1997;272(35):22364-72.
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1997: Lomakin A; Teplow D B; Kirschner D A; Benedek G B
Kinetic theory of fibrillogenesis of amyloid beta-protein.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):7942-7.
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1997: Xia W; Zhang J; Kholodenko D; Citron M; Podlisny M B; Teplow D B; Haass C; Seubert P; Koo E H; Selkoe D J
Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.
The Journal of biological chemistry 1997;272(12):7977-82.
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1997: Podlisny M B; Citron M; Amarante P; Sherrington R; Xia W; Zhang J; Diehl T; Levesque G; Fraser P; Haass C; Koo E H; Seubert P; St George-Hyslop P; Teplow D B; Selkoe D J
Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
Neurobiology of disease 1997;3(4):325-37.
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1996: Citron M; Diehl T S; Capell A; Haass C; Teplow D B; Selkoe D J
Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF.
Neuron 1996;17(1):171-9.
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1996: Tamaoka A; Endoh R; Shoji S; Takahashi H; Hirokawa K; Teplow D B; Selkoe D J; Mori H
Antibodies to amyloid beta protein (A beta) crossreact with glyceraldehyde-3-phosphate dehydrogenase (GAPDH).
Neurobiology of aging 1996;17(3):405-14.
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1996: Qiu W Q; Borth W; Ye Z; Haass C; Teplow D B; Selkoe D J
Degradation of amyloid beta-protein by a serine protease-alpha2-macroglobulin complex.
The Journal of biological chemistry 1996;271(14):8443-51.
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1996: Thinakaran G; Teplow D B; Siman R; Greenberg B; Sisodia S S
Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
The Journal of biological chemistry 1996;271(16):9390-7.
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1996: Lomakin A; Chung D S; Benedek G B; Kirschner D A; Teplow D B
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1125-9.
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1996: Selkoe D J; Yamazaki T; Citron M; Podlisny M B; Koo E H; Teplow D B; Haass C
The role of APP processing and trafficking pathways in the formation of amyloid beta-protein.
Annals of the New York Academy of Sciences 1996;777():57-64.
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1995: Munger J S; Haass C; Lemere C A; Shi G P; Wong W S; Teplow D B; Selkoe D J; Chapman H A
Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S.
The Biochemical journal 1995;311 ( Pt 1)():299-305.
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1995: Stamey T A; Teplow D B; Graves H C
Identity of PSA purified from seminal fluid by different methods: comparison by amino acid analysis and assigned extinction coefficients.
The Prostate 1995;27(4):198-203.
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1995: Chen S G; Teplow D B; Parchi P; Teller J K; Gambetti P; Autilio-Gambetti L
Truncated forms of the human prion protein in normal brain and in prion diseases.
The Journal of biological chemistry 1995;270(32):19173-80.
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1995: Podlisny M B; Ostaszewski B L; Squazzo S L; Koo E H; Rydell R E; Teplow D B; Selkoe D J
Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.
The Journal of biological chemistry 1995;270(16):9564-70.
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1995: Haass C; Capell A; Citron M; Teplow D B; Selkoe D J
The vacuolar H(+)-ATPase inhibitor bafilomycin A1 differentially affects proteolytic processing of mutant and wild-type beta-amyloid precursor protein.
The Journal of biological chemistry 1995;270(11):6186-92.
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1995: Haas C; Hung A Y; Citron M; Teplow D B; Selkoe D J
beta-Amyloid, protein processing and Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):398-402.
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1995: Citron M; Teplow D B; Selkoe D J
Generation of amyloid beta protein from its precursor is sequence specific.
Neuron 1995;14(3):661-70.
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1995: Haass C; Koo E H; Capell A; Teplow D B; Selkoe D J
Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
The Journal of cell biology 1995;128(4):537-47.
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1994: Citron M; Vigo-Pelfrey C; Teplow D B; Miller C; Schenk D; Johnston J; Winblad B; Venizelos N; Lannfelt L; Selkoe D J
Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):11993-7.
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1994: Lo A C; Haass C; Wagner S L; Teplow D B; Sisodia S S
Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells.
The Journal of biological chemistry 1994;269(49):30966-73.
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1994: Haass C; Hung A Y; Selkoe D J; Teplow D B
Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.
The Journal of biological chemistry 1994;269(26):17741-8.
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1994: Brandt R; Lee G; Teplow D B; Shalloway D; Abdel-Ghany M
Differential effect of phosphorylation and substrate modulation on tau's ability to promote microtubule growth and nucleation.
The Journal of biological chemistry 1994;269(16):11776-82.
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1994: Haass C; Koo E H; Teplow D B; Selkoe D J
Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1564-8.
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1993: Haass C; Hung A Y; Schlossmacher M G; Oltersdorf T; Teplow D B; Selkoe D J
Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules.
Annals of the New York Academy of Sciences 1993;695():109-16.
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1993: Stahl N; Baldwin M A; Teplow D B; Hood L; Gibson B W; Burlingame A L; Prusiner S B
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.
Biochemistry 1993;32(8):1991-2002.
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1993: Ashkar S; Teplow D B; Glimcher M J; Saavedra R A
In vitro phosphorylation of mouse osteopontin expressed in E. coli.
Biochemical and biophysical research communications 1993;191(1):126-33.
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1993: Haass C; Hung A Y; Schlossmacher M G; Teplow D B; Selkoe D J
beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
The Journal of biological chemistry 1993;268(5):3021-4.
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1993: Weiler S; Carson W; Lee Y; Teplow D B; Kishimoto Y; O'Brien J S; Barranger J A; Tomich J M
Synthesis and characterization of a bioactive 82-residue sphingolipid activator protein, saposin C.
Journal of molecular neuroscience : MN 1993;4(3):161-72.
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1992: Haass C; Schlossmacher M G; Hung A Y; Vigo-Pelfrey C; Mellon A; Ostaszewski B L; Lieberburg I; Koo E H; Schenk D; Teplow D B
Amyloid beta-peptide is produced by cultured cells during normal metabolism.
Nature 1992;359(6393):322-5.
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1992: Karthigasan J; Bauer T K; Teplow D B; Saavedra R A; Kirschner D A
Phylogenetically conserved amino acids of MBP and P0 from amphibian myelin.
Journal of molecular neuroscience : MN 1992;3(4):185-8.
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1991: Karthigasan J; Bauer T K; Teplow D B; Saavedra R A; Kirschner D A
Generation of DM-20 splice site in myelin proteolipid protein gene: a hypothesis based on analysis of the amphibian protein.
Peptide research 1991;4(4):227-9.
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1990: Kingan T G; Teplow D B; Phillips J M; Riehm J P; Rao K R; Hildebrand J G; Homberg U; Kammer A E; Jardine I; Griffin P R
A new peptide in the FMRFamide family isolated from the CNS of the hawkmoth, Manduca sexta.
Peptides 1990;11(4):849-56.
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1990: Oesch B; Teplow D B; Stahl N; Serban D; Hood L E; Prusiner S B
Identification of cellular proteins binding to the scrapie prion protein.
Biochemistry 1990;29(24):5848-55.
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1988: Turk E; Teplow D B; Hood L E; Prusiner S B
Purification and properties of the cellular and scrapie hamster prion proteins.
European journal of biochemistry / FEBS 1988;176(1):21-30.
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1988: Teplow D B; Nakayama C; Leung P C; Harshey R M
Structure-function relationships in the transposition protein B of bacteriophage Mu.
The Journal of biological chemistry 1988;263(22):10851-7.
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1987: Tacke R; Moos M; Teplow D B; Früh K; Scherer H; Bach A; Schachner M
Identification of cDNA clones of the mouse neural cell adhesion molecule L1.
Neuroscience letters 1987;82(1):89-94.
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1986: Flanagan B F; Teplow D B; Dreyer W J; Fabre J W
Unusual phylogenetic conservation of the N-terminal amino acid sequence of the central nervous system-specific membrane glycoprotein F3-87-8 (CNSgp130).
Journal of neurochemistry 1986;46(2):542-4.
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1985: Oesch B; Westaway D; Wälchli M; McKinley M P; Kent S B; Aebersold R; Barry R A; Tempst P; Teplow D B; Hood L E
A cellular gene encodes scrapie PrP 27-30 protein.
Cell 1985;40(4):735-46.
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