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Alessandro Terrinoni

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Genes, Tumor Suppressor

Anatomy

Physiology

Living Beings

Mouse

Disorders

Keratoderma, Palmoplantar

Co-author Network

Publications

TOP 3
Arianna Giacobbe; Arnold J Levine; Elke Katrin Markert; Gerry Melino; Daniel A Notterman; Massimilano Agostini; Alessandro Finazzi Agrò; Francesca Bernassola; Lucilla Bongiorno-Borbone; Zhaohui Feng; Alessandro Terrinoni; Lello Zolla; Angelo Peschiaroli
p63 regulates glutaminase 2 expression.
Elena Campione; Sergio Chimenti; Alessandro Di Stefani; L Diluvio; Augusto Orlandi; Alessandro Terrinoni; L Bianchi
Progressive late-onset of cutaneous angiomatosis as possible sign of cerebral cavernous malformations.
Ivano Amelio; Elena Bonanno; Eleonora Candi; David Dinsdale; Claudia Fortunato; Richard Austen Knight; Anna Maria Lena; Giandomenico Russo; Ruby Shalom-Feuerstein; Luigi Giusto Spagnoli; Alessandro Terrinoni; Giuditta Viticchiè; Daniel Aberdam; Gerry Melino
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration.

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All Publications

2013: Arianna Giacobbe; Arnold J Levine; Elke Katrin Markert; Gerry Melino; Daniel A Notterman; Massimilano Agostini; Alessandro Finazzi Agrò; Francesca Bernassola; Lucilla Bongiorno-Borbone; Zhaohui Feng; Alessandro Terrinoni; Lello Zolla; Angelo Peschiaroli
p63 regulates glutaminase 2 expression.
Cell cycle (Georgetown, Tex.) 2013;12(9):1395-405.
2013: Elena Campione; Sergio Chimenti; Alessandro Di Stefani; L Diluvio; Augusto Orlandi; Alessandro Terrinoni; L Bianchi
Progressive late-onset of cutaneous angiomatosis as possible sign of cerebral cavernous malformations.
Dermatology online journal 2013;19(2):2.
2012: Ivano Amelio; Elena Bonanno; Eleonora Candi; David Dinsdale; Claudia Fortunato; Richard Austen Knight; Anna Maria Lena; Giandomenico Russo; Ruby Shalom-Feuerstein; Luigi Giusto Spagnoli; Alessandro Terrinoni; Giuditta Viticchiè; Daniel Aberdam; Gerry Melino
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration.
The Journal of cell biology 2012;199(2):347-63.
2012: Paola Tucci; Peter Vandenabeele; Karen H Vousden; Patricia A J Muller; Berna S Sayan; Nozomi Takahashi; Alessandro Terrinoni; Massimiliano Agostini; Volker Dötsch; Giuseppe Giaccone; Francesca Grespi; Sebastian Kehrloesser; Richard A Knight; Arnold J Levine; Scott W Lowe; Elke K Markert; Gerry Melino
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(38):15312-7.
2012: Alessandro Terrinoni; Giovanna Zambruno; M Annicchiarico-Petruzzelli; L Bui; Elena Campione; A Codispoti; Biagio Didona; Gerry Melino; R Palombo; V Serra; M Sette; E Talamonti; Eleonora Candi
Novel transglutaminase 1 mutations in patients affected by lamellar ichthyosis.
Cell death & disease 2012;3():e416.
2011: Valeria Serra; Laura Bui; Marco Castori; Gerry Melino; Mauro Paradisi; Alessandro Terrinoni
Functional characterization of a novel TP63 mutation in a family with overlapping features of Rapp-Hodgkin/AEC/ADULT syndromes.
American journal of medical genetics. Part A 2011;155A(12):3104-9.
2011: Stefano Rufini; Alessandro Terrinoni; Ivano Amelio; Bruno CADOT; Alessandro Desideri; Anna Maria Lena; Sonia Mele; Gerry Melino; Eleonora Candi
The sterile alpha-motif (SAM) domain of p63 binds in vitro monoasialoganglioside (GM1) micelles.
Biochemical pharmacology 2011;82(10):1262-8.
2011: Alessandro Terrinoni; I Zucchi; F L Curto; F Rovera; V Serra; S Sirchia; A Albertini; C Capella; A M Chiaravalli; F Lo Curto; G Dionigi; A Ferrari; A Frattini; Gerry Melino; M Miozzo; I S Pagani; F Pasquali; G Porta
OTX1 expression in breast cancer is regulated by p53.
Oncogene 2011;30(27):3096-103.
2011: Gareth Browne; Eleonora Candi; Rita Cipollone; Volker Dötsch; Richard A Knight; Anna Maria Lena; Roberto Mantovani; Daniele Merico; Valeria Serra; Alessandro Terrinoni; Hans van Bokhoven; Huiqing Zhou; Gerry Melino
Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias.
Journal of cell science 2011;124(Pt 13):2200-7.
2011: Patrizia Vernole; Alessia Muzi; Antonio Volpi; Alessandro Terrinoni; Annalisa Susanna Dorio; Lucio Tentori; Girish M Shah; Grazia Graziani
Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1.
Mutation research 2011;712(1-2):40-8.
2010: Ilaria S Pagani; Alessandro Terrinoni; Laura Marenghi; Ileana Zucchi; Anna M Chiaravalli; Valeria Serra; Francesca Rovera; Silvia Sirchia; Gianlorenzo Dionigi; Monica Mozzo; Annalisa Frattini; Alberta Ferrari; Carlo Capella; Francesco Pasquali; Francesco L Curto; Alberto Albertini; Gerry Melino; Francesco Lo Curto; Monica Miozzo; Giovanni Porta
The mammary gland and the homeobox gene Otx1.
The breast journal 2010;16 Suppl 1():S53-6.
2010: Markus A Keller; Katrin Watschinger; Georg Golderer; Manuel Maglione; Bettina Sarg; Herbert H Lindner; Gabriele Werner-Felmayer; Alessandro Terrinoni; Ronald J A Wanders; Ernst R Werner
Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal.
Journal of lipid research 2010;51(6):1554-9.
2010: Alessandro Terrinoni; Andrea Codispoti; Valeria Serra; Ernesto Bruno; Biagio Didona; Mauro Paradisi; Steven Nisticò; Elena Campione; Bianca Napolitano; Laura Diluvio; Gerry Melino
Connexin 26 (GJB2) mutations as a cause of the KID syndrome with hearing loss.
Biochemical and biophysical research communications 2010;395(1):25-30.
2010: Alessandro Terrinoni; Andrea Codispoti; Valeria Serra; Biagio Didona; Ernesto Bruno; Robert Nisticò; Michela Giustizieri; Marco Alessandrini; Elena Campione; Gerry Melino
Connexin 26 (GJB2) mutations, causing KID Syndrome, are associated with cell death due to calcium gating deregulation.
Biochemical and biophysical research communications 2010;394(4):909-14.
2009: Elena Campione; Laura Diluvio; Evelin J Paternò; Dely Di Marcantonio; Arianna Francesconi; Alessandro Terrinoni; Augusto Orlandi; Sergio Chimenti
Kaposi's sarcoma in a patient treated with imatinib mesylate for chronic myeloid leukemia.
Clinical therapeutics 2009;31(11):2565-9.
2009: Rossella Menghini; Viviana Casagrande; Marina Cardellini; E Martelli; Alessandro Terrinoni; Francesca Amati; Mariuca Vasa-Nicotera; Arnaldo Ippoliti; Giuseppe Novelli; Gerry Melino; Renato Lauro; Massimo Federici
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.
Circulation 2009;120(15):1524-32.
2009: Patrizia Vernole; Alessia Muzi; Antonio Volpi; Annalisa S Dorio; Alessandro Terrinoni; Girish M Shah; Grazia Graziani
Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.
Mutation research 2009;664(1-2):39-47.
2009: Andrea Codispoti; Enrico Colombo; Loredana Zocchi; Valeria Serra; Ginevra Pertusi; Giorgio Leigheb; Rossana Tiberio; Guido Bornacina; Riccardo Zuccoli; Antonio Ramponi; Elena Campione; Gerry Melino; Alessandro Terrinoni
Knuckle pads, in an epidermal palmoplantar keratoderma patient with Keratin 9 R163W transgrediens expression.
European journal of dermatology : EJD 2009;19(2):114-8.
2009: Laura Diluvio; Elena Campione; Evelin Jasmine Paternò; Augusto Orlandi; Alessandro Terrinoni; Sergio Chimenti
Peculiar clinical and dermoscopic remission pattern following imiquimod therapy of basal cell carcinoma in seborrhoeic areas of the face.
The Journal of dermatological treatment 2009;20(2):124-9.
2008: Loredana Zocchi; Jean Christophe Bourdon; Andrea Codispoti; Richard Knight; David P Lane; Gerry Melino; Alessandro Terrinoni
Scotin: A new p63 target gene expressed during epidermal differentiation.
Biochemical and biophysical research communications 2008;367(2):271-6.
2007: Ottavia Porzio; Ornella Massa; Veronica Cunsolo; C Colombo; M Malaponti; Federico Bertuzzi; T Hansen; A Johansen; Oluf Pedersen; Franco Meschi; Alessandro Terrinoni; Gerry Melino; Massimo Federici; N Decarlo; Michele Menicagli; Daniela Campani; Piero Marchetti; M Ferdaoussi; philippe froguel; Giorgio Federici; Martine Vaxillaire; Fabrizio Barbetti
Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online.
Human mutation 2007;28(11):1150.
2007: Elena Campione; Alessandro Terrinoni; Augusto Orlandi; Andrea Codispoti; Gerry Melino; Luca Bianchi; Annamaria Mazzotta; Francesco Giuseppe Garaci; Andrea Ludovici; Sergio Chimenti
Cerebral cavernomas in a family with multiple cutaneous and uterine leiomyomas associated with a new mutation in the fumarate hydratase gene.
The Journal of investigative dermatology 2007;127(9):2271-3.
2007: Eleonora Candi; Alessandra Rufini; Alessandro Terrinoni; Alessandro Giamboi-Miraglia; Anna Maria Lena; Roberto Mantovani; Richard Knight; Gerry Melino
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):11999-2004.
2007: Carlo Nucci; Valeria Gasperi; Rosanna Tartaglione; Angelica Cerulli; Alessandro Terrinoni; Monica Bari; Chiara De Simone; Alessandro Finazzi Agrò; Luigi A Morrone; M Tiziana Corasaniti; Giacinto Bagetta; Mauro Maccarrone
Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats.
Investigative ophthalmology & visual science 2007;48(7):2997-3004.
2007: Loredana Zocchi; Alessandro Terrinoni; Eleonora Candi; Bijan Ahvazi; Giacinto Bagetta; M Tiziana Corasaniti; Anna M Lena; Gerry Melino
Identification of transglutaminase 3 splicing isoforms.
The Journal of investigative dermatology 2007;127(7):1791-4.
2007: Biagio Didona; Andrea Codispoti; Enrico Bertini; William B Rizzo; Gael Carney; Giovanna Zambruno; Carlo Dionisi Vici; Mauro Paradisi; Cristina Pedicelli; Gerry Melino; Alessandro Terrinoni
Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren-Larsson syndrome.
Journal of human genetics 2007;52(10):865-70.
2006: Raffaella Ponassi; Alessandro Terrinoni; Anissa Chikh; Alessandra Rufini; Anna Maria Lena; Berna S Sayan; Gerry Melino; Eleonora Candi
p63 and p73, members of the p53 gene family, transactivate PKCdelta.
Biochemical pharmacology 2006;72(11):1417-22.
2006: Eleonora Candi; Alessandro Terrinoni; Alessandra Rufini; Anissa Chikh; Anna Maria Lena; Yasuhiro Suzuki; Berna S Sayan; Richard A Knight; Gerry Melino
p63 is upstream of IKK alpha in epidermal development.
Journal of cell science 2006;119(Pt 22):4617-22.
2006: Daniela Barcaroli; L Bongiorno-Borbone; Alessandro Terrinoni; T G Hofmann; Mario Rossi; Richard A Knight; A G Matera; Gerry Melino; Vincenzo de Laurenzi
FLASH is required for histone transcription and S-phase progression.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14808-12.
2006: Eleonora Candi; Alessandra Rufini; Alessandro Terrinoni; David Dinsdale; Marco Ranalli; Andrea Paradisi; Vincenzo de Laurenzi; Luigi Giusto Spagnoli; Maria Valeria Catani; Safaa Ramadan; Richard A Knight; Gerry Melino
Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice.
Cell death and differentiation 2006;13(6):1037-47.
2005: Andrew J Cassidy; Maurice A M van Steensel; Peter M Steijlen; Michel van Geel; Jaap van der Velden; Susan M Morley; Alessandro Terrinoni; Gerry Melino; Eleonora Candi; W H Irwin McLean
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome.
American journal of human genetics 2005;77(6):909-17.
2005: Olav Gressner; Tobias Schilling; Katja Lorenz; Elisa Schulze Schleithoff; Andreas Koch; Henning Schulze-Bergkamen; Anna Maria Lena; Eleonora Candi; Alessandro Terrinoni; Maria Valeria Catani; Moshe Oren; Gerry Melino; Peter H Krammer; Wolfgang Stremmel; Martina Müller
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria.
The EMBO journal 2005;24(13):2458-71.
2005: Safaa Ramadan; Alessandro Terrinoni; Maria Valeria Catani; emre sayan; Richard A Knight; Martina Mueller; Peter H Krammer; Gerry Melino; Eleonora Candi
p73 induces apoptosis by different mechanisms.
Biochemical and biophysical research communications 2005;331(3):713-7.
2004: Mario Rossi; emre sayan; Alessandro Terrinoni; Gerry Melino; Richard A Knight
Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology.
Annals of the New York Academy of Sciences 2004;1028():143-9.
2004: Eliana Munarriz; Daniela Barcaroli; Anastasis Stephanou; Paul A Townsend; Carine Maisse; Alessandro Terrinoni; Michael H Neale; Seamus Martin; David S Latchman; Richard A Knight; Gerry Melino; Vincenzo de Laurenzi
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73.
Molecular and cellular biology 2004;24(24):10593-610.
2004: Alessandro Terrinoni; Barbara Cocuroccia; Emanuela Gubinelli; Giovanna Zambruno; Eleonora Candi; Gerry Melino; Giampiero Girolomoni
Identification of the keratin K9 R162W mutation in patients of Italian origin with epidermolytic palmoplantar keratoderma.
European journal of dermatology : EJD 2004;14(6):375-8.
2004: Eleonora Candi; Andrea Paradisi; Alessandro Terrinoni; Valentina Pietroni; Sergio Oddi; Bruno CADOT; Vishwanath Jogini; Muthuraman Meiyappan; Jon Clardy; Alessandro Finazzi-Agro; Gerry Melino
Transglutaminase 5 is regulated by guanine-adenine nucleotides.
The Biochemical journal 2004;381(Pt 1):313-9.
2004: Ana Terron-Kwiatkowski; Alessandro Terrinoni; Biagio Didona; Gerry Melino; David J Atherton; Alan D Irvine; W H Irwin McLean
Atypical epidermolytic palmoplantar keratoderma presentation associated with a mutation in the keratin 1 gene.
The British journal of dermatology 2004;150(6):1096-103.
2004: Alessandro Terrinoni; Marco Ranalli; Bruno CADOT; Aida Leta; Giacinto Bagetta; Karen H Vousden; Gerry Melino
p73-alpha is capable of inducing scotin and ER stress.
Oncogene 2004;23(20):3721-5.
2004: Alessandro Terrinoni; Aida Leta; Cristina Pedicelli; Eleonora Candi; Marco Ranalli; Pietro Puddu; Mauro Paradis; Corrado Angelo; Giacinto Bagetta; Gerry Melino; Giancinto Baggetta
A novel recessive connexin 31 (GJB3) mutation in a case of erythrokeratodermia variabilis.
The Journal of investigative dermatology 2004;122(3):837-9.
2004: Nathalie Billon; Alessandro Terrinoni; Christine Jolicoeur; Afshan McCarthy; William D Richardson; Gerry Melino; Martin Raff
Roles for p53 and p73 during oligodendrocyte development.
Development (Cambridge, England) 2004;131(6):1211-20.
2003: Georgiana Clare Marulli; Elena Campione; Maria Sole Chimenti; Alessandro Terrinoni; Gerry Melino; Luca Bianchi
Type I lamellar ichthyosis improved by tazarotene 0.1% gel.
Clinical and experimental dermatology 2003;28(4):391-3.
2002: Eleonora Candi; Sergio Oddi; Andrea Paradisi; Alessandro Terrinoni; Marco Ranalli; Patrizia Teofoli; Gennaro Citro; Silvia Scarpato; Pietro Puddu; Gerry Melino
Expression of transglutaminase 5 in normal and pathologic human epidermis.
The Journal of investigative dermatology 2002;119(3):670-7.
2002: Francesca Bernassola; Massimo Federici; Marco Corazzari; Alessandro Terrinoni; Marta Letizia Hribal; Vincenzo de Laurenzi; Marco Ranalli; Ornella Massa; Giorgio Sesti; W H Irwin McLean; Gennaro Citro; Fabrizio Barbetti; Gerry Melino
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1371-8.
2002: Bruna Pucci; Pier Paolo Claudio; Valeria Masciullo; Lorenza Bellincampi; Alessandro Terrinoni; Kamel Khalili; Gerry Melino; Antonio Giordano
pRb2/p130 promotes radiation-induced cell death in the glioblastoma cell line HJC12 by p73 upregulation and Bcl-2 downregulation.
Oncogene 2002;21(38):5897-905.
2001: Alessandro Terrinoni; Frances J D Smith; Biagio Didona; F Canzona; Mauro Paradisi; M Huber; Daniel Hohl; A David; Alain Verloes; I M Leigh; Colin S Munro; Gerry Melino; W H Irwin McLean
Novel and recurrent mutations in the genes encoding keratins K6a, K16 and K17 in 13 cases of pachyonychia congenita.
The Journal of investigative dermatology 2001;117(6):1391-6.
2001: Eleonora Candi; Sergio Oddi; Alessandro Terrinoni; Andrea Paradisi; Marco Ranalli; Alessandro Finazzi-Agró; Gerry Melino
Transglutaminase 5 cross-links loricrin, involucrin, and small proline-rich proteins in vitro.
The Journal of biological chemistry 2001;276(37):35014-23.
2001: Alessandro Terrinoni; Elizabeth L Rugg; E Birgitte Lane; G Melino; D H Felix; Colin S Munro; W H Irwin McLean
A novel mutation in the keratin 13 gene causing oral white sponge nevus.
Journal of dental research 2001;80(3):919-23.
2000: Vincenzo de Laurenzi; Antonello Rossi; Alessandro Terrinoni; Daniela Barcaroli; Massimo Levrero; Antonio Costanzo; Richard A Knight; Piero Guerrieri; Gerry Melino
p63 and p73 transactivate differentiation gene promoters in human keratinocytes.
Biochemical and biophysical research communications 2000;273(1):342-6.
2000: Alessandro Terrinoni; Pietro Puddu; Biagio Didona; Vincenzo de Laurenzi; Eleonora Candi; Frances J D Smith; W H Irwin McLean; Gerry Melino
A mutation in the V1 domain of K16 is responsible for unilateral palmoplantar verrucous nevus.
The Journal of investigative dermatology 2000;114(6):1136-40.
2000: Alessandro Terrinoni; Eleonora Candi; Sergio Oddi; Tommaso Gobello; D B Camaione; Cinzia Mazzanti; Giovanna Zambruno; R Knight; Gerry Melino
A glutamine insertion in the 1A alpha helical domain of the keratin 4 gene in a familial case of white sponge nevus.
The Journal of investigative dermatology 2000;114(2):388-91.
2000: Patrizia Vernole; Alessandro Terrinoni; Biagio Didona; Vincenzo de Laurenzi; Paolo Rossi; Gerry Melino; Paola Grimaldi
An SRY-negative XX male with Huriez syndrome.
Clinical genetics 2000;57(1):61-6.
1999: Vincenzo de Laurenzi; Maria Valeria Catani; Alessandro Terrinoni; Marco Corazzari; Gerry Melino; Antonio Costanzo; Massimo Levrero; Richard A Knight
Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta.
Cell death and differentiation 1999;6(5):389-90.
1998: Vincenzo de Laurenzi; Antonio Costanzo; Daniela Barcaroli; Alessandro Terrinoni; M Falco; M Annicchiarico-Petruzzelli; Massimo Levrero; Gerry Melino
Two new p73 splice variants, gamma and delta, with different transcriptional activity.
The Journal of experimental medicine 1998;188(9):1763-8.
1998: Gerry Melino; Vincenzo de Laurenzi; Maria Valeria Catani; Alessandro Terrinoni; B Ciani; Eleonora Candi; Lyuben Marekov; Peter M Steinert
The cornified envelope: a model of cell death in the skin.
Results and problems in cell differentiation 1998;24():175-212.