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Leon Thal

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Vellas Bruno; Black R; Thal Leon J; Fox Nick C; Daniels M; McLennan G; Tompkins C; Leibman C; Pomfret M; Grundman Michael;
Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders.
Hamilton Joanne M; Salmon David P; Galasko Douglas; Raman Rema; Emond Jenn; Hansen Lawrence A; Masliah Eliezer; Thal Leon J
Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies.
Aisen Paul S; Schneider Lon S; Sano Mary; Diaz-Arrastia Ramon; van Dyck Christopher H; Weiner Myron F; Bottiglieri Teodoro; Jin Shelia; Stokes Karen T; Thomas Ronald G; Thal Leon J;
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.

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All Publications

2009: Vellas Bruno; Black R; Thal Leon J; Fox Nick C; Daniels M; McLennan G; Tompkins C; Leibman C; Pomfret M; Grundman Michael;
Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders.
Current Alzheimer research 2009;6(2):144-51.
2008: Hamilton Joanne M; Salmon David P; Galasko Douglas; Raman Rema; Emond Jenn; Hansen Lawrence A; Masliah Eliezer; Thal Leon J
Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies.
Neuropsychology 2008;22(6):729-37.
2008: Aisen Paul S; Schneider Lon S; Sano Mary; Diaz-Arrastia Ramon; van Dyck Christopher H; Weiner Myron F; Bottiglieri Teodoro; Jin Shelia; Stokes Karen T; Thomas Ronald G; Thal Leon J;
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2008;300(15):1774-83.
2008: van Straaten Elisabeth C W; Harvey Danielle; Scheltens Philip; Barkhof Frederik; Petersen Ronald C; Thal Leon J; Jack Clifford R; DeCarli Charles;
Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia.
Journal of neurology 2008;255(9):1302-8.
2008: Jack Clifford R; Petersen Ronald C; Grundman Michael; Jin Shelia; Gamst Anthony; Ward Chadwick P; Sencakova Drahomira; Doody Rachelle S; Thal Leon J;
Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI.
Neurobiology of aging 2008;29(9):1285-95.
2008: Fleisher Adam S; Raman Rema; Siemers Eric R; Becerra Lida; Clark Christopher M; Dean Robert A; Farlow Martin R; Galvin James E; Peskind Elaine R; Quinn Joseph F; Sherzai Abdullah; Sowell B Brooke; Aisen Paul S; Thal Leon J
Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease.
Archives of neurology 2008;65(8):1031-8.
2008: Delano-Wood Lisa; Houston Wes S; Emond Jennifer A; Marchant Natalie L; Salmon David P; Jeste Dilip V; Thal Leon J; Bondi Mark W
APOE genotype predicts depression in women with Alzheimer's disease: a retrospective study.
International journal of geriatric psychiatry 2008;23(6):632-6.
2008: Fine Eric M; Delis Dean C; Wetter Spencer R; Jacobson Mark W; Jak Amy J; McDonald Carrie R; Braga Jodessa C; Thal Leon J; Salmon David P; Bondi Mark W
Cognitive discrepancies versus APOE genotype as predictors of cognitive decline in normal-functioning elderly individuals: a longitudinal study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2008;16(5):366-74.
2008: Li Yonghong; Grupe Andrew; Rowland Charles; Holmans Peter; Segurado Ricardo; Abraham Richard; Jones Lesley; Catanese Joseph; Ross David; Mayo Kevin; Martinez Maribel; Hollingworth Paul; Goate Alison; Cairns Nigel J; Racette Brad A; Perlmutter Joel S; O'Donovan Michael C; Morris John C; Brayne Carol; Rubinsztein David C; Lovestone Simon; Thal Leon J; Owen Michael J; Williams Julie
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Aisen Paul S; Thal Leon J; Ferris Steven H; Assaid Christopher; Nessly Michael L; Giuliani Michael J; Lines Christopher R; Norman Barbara A; Potter William Z
Rofecoxib in patients with mild cognitive impairment: further analyses of data from a randomized, double-blind, trial.
Current Alzheimer research 2008;5(1):73-82.
2008: Fleisher A S; Sun S; Taylor C; Ward C P; Gamst A C; Petersen R C; Jack C R; Aisen P S; Thal L J
Volumetric MRI vs clinical predictors of Alzheimer disease in mild cognitive impairment.
Neurology 2008;70(3):191-9.
2007: Mickes Laura; Wixted John T; Fennema-Notestine Christine; Galasko Douglas; Bondi Mark W; Thal Leon J; Salmon David P
Progressive impairment on neuropsychological tasks in a longitudinal study of preclinical Alzheimer's disease.
Neuropsychology 2007;21(6):696-705.
2007: Weisman D; Cho M; Taylor C; Adame A; Thal L J; Hansen L A
In dementia with Lewy bodies, Braak stage determines phenotype, not Lewy body distribution.
Neurology 2007;69(4):356-9.
2007: Galasko D; Salmon D; Gamst A; Olichney J; Thal L J; Silbert L; Kaye J; Brooks P; Adonay R; Craig U-K; Schellenberg G; Borenstein A R
Prevalence of dementia in Chamorros on Guam: relationship to age, gender, education, and APOE.
Neurology 2007;68(21):1772-81.
2007: Borenstein A R; Mortimer J A; Schofield E; Wu Y; Salmon D P; Gamst A; Olichney J; Thal L J; Silbert L; Kaye J; Craig U L; Schellenberg G D; Galasko D R
Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam.
Neurology 2007;68(21):1764-71.
2007: Weisman David C; Yaari Roy; Hansen Lawrence A; Thal Leon J
Density of the brain, decline of the mind: an atypical case of Fahr disease.
Archives of neurology 2007;64(5):756-7.
2007: Fleisher A S; Sowell B B; Taylor C; Gamst A C; Petersen R C; Thal L J;
Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment.
Neurology 2007;68(19):1588-95.
2007: Kurlan Roger; Cummings Jeffrey; Raman Rema; Thal Leon;
Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
Neurology 2007;68(17):1356-63.
2007: Grupe Andrew; Abraham Richard; Li Yonghong; Rowland Charles; Hollingworth Paul; Morgan Angharad; Jehu Luke; Segurado Ricardo; Stone David; Schadt Eric; Karnoub Maha; Nowotny Petra; Tacey Kristina; Catanese Joseph; Sninsky John; Brayne Carol; Rubinsztein David; Gill Michael; Lawlor Brian; Lovestone Simon; Holmans Peter; O'Donovan Michael; Morris John C; Thal Leon; Goate Alison; Owen Michael J; Williams Julie
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Human molecular genetics 2007;16(8):865-73.
2007: Frielingsdorf Helena; Simpson Daniel R; Thal Leon J; Pizzo Donald P
Nerve growth factor promotes survival of new neurons in the adult hippocampus.
Neurobiology of disease 2007;26(1):47-55.
2007: Han S Duke; Houston Wes S; Jak Amy J; Eyler Lisa T; Nagel Bonnie J; Fleisher Adam S; Brown Gregory G; Corey-Bloom Jody; Salmon David P; Thal Leon J; Bondi Mark W
Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response.
Neurobiology of aging 2007;28(2):238-47.
2007: Thal Leon; Kuller Lewis; Bowman Keith; Breitner John; Evans Denis; Farrer Lindsey; Frank Richard; Khachaturian Ara S; Khachaturian Zaven S; Kukull Walter; Nieto Javier; Petersen Ronald; Sager Mark; Scherr Paul; Bain Lisa J
The Nevada Vital Aging Initiative: A private-public partnership to study early predictors of dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2007;3(1):62-7.
2007: DeCarli Charles; Frisoni Giovanni B; Clark Christopher M; Harvey Danielle; Grundman Michael; Petersen Ronald C; Thal Leon J; Jin Shelia; Jack Clifford R; Scheltens Philip;
Qualitative estimates of medial temporal atrophy as a predictor of progression from mild cognitive impairment to dementia.
Archives of neurology 2007;64(1):108-15.
2007: Rascovsky Katya; Salmon David P; Hansen Lawrence A; Thal Leon J; Galasko Douglas
Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease.
Neuropsychology 2007;21(1):20-30.
2007: Fennema-Notestine Christine; Gamst Anthony C; Quinn Brian T; Pacheco Jenni; Jernigan Terry L; Thal Leon; Buckner Randy; Killiany Ron; Blacker Deborah; Dale Anders M; Fischl Bruce; Dickerson Brad; Gollub Randy L
Feasibility of multi-site clinical structural neuroimaging studies of aging using legacy data.
Neuroinformatics 2007;5(4):235-45.
2007: Wahrle Suzanne E; Shah Aarti R; Fagan Anne M; Smemo Scott; Kauwe John S K; Grupe Andrew; Hinrichs Anthony; Mayo Kevin; Jiang Hong; Thal Leon J; Goate Alison M; Holtzman David M
Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms.
Molecular neurodegeneration 2007;2():7.
2006: Flint Beal M; Bossy-Wetzel Ella; Finkbeiner Steven; Fiskum Gary; Giasson Benoit; Johnson Carl; Khachaturian Zaven S; Lee Virginia M-Y; Nicholls David; Reddy Hemachandra; Reynolds Ian; Teplow David B; Thal Leon J; Trojanowski John Q; Walsh Dominic M; Wetzel Ronald; Wexler Nancy S; Young Anne B; Bain Lisa
Common threads in neurodegenerative disorders of aging.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(4):322-6.
2006: Sano Mary; Zhu Carolyn W; Whitehouse Peter J; Edland Steven; Jin Shelia; Ernstrom Karin; Thomas Ronald G; Thal Leon J; Ferris Steven H;
ADCS Prevention Instrument Project: pharmacoeconomics: assessing health-related resource use among healthy elderly.
Alzheimer disease and associated disorders 2006;20(4 Suppl 3):S191-202.
2006: Salmon David P; Cummings Jeffrey L; Jin Shelia; Sano Mary; Sperling Reisa A; Zamrini Edward; Petersen Ronald C; Edland Steven D; Thal Leon J; Ferris Steven H;
ADCS Prevention Instrument Project: development of a brief verbal memory test for primary prevention clinical trials.
Alzheimer disease and associated disorders 2006;20(4 Suppl 3):S139-46.
2006: Ferris Steven H; Aisen Paul S; Cummings Jeffrey; Galasko Douglas; Salmon David P; Schneider Lon; Sano Mary; Whitehouse Peter J; Edland Steven; Thal Leon J;
ADCS Prevention Instrument Project: overview and initial results.
Alzheimer disease and associated disorders 2006;20(4 Suppl 3):S109-23.
2006: Sano Mary; Egelko Susan; Jin Shelia; Cummings Jeffrey; Clark Christopher M; Pawluczyk Sonia; Thomas Ronald J; Schittini Mario; Thal Leon J;
Spanish instrument protocol: new treatment efficacy instruments for Spanish-speaking patients in Alzheimer disease clinical trials.
Alzheimer disease and associated disorders 2006;20(4):232-41.
2006: Li Yonghong; Grupe Andrew; Rowland Charles; Nowotny Petra; Kauwe John S K; Smemo Scott; Hinrichs Anthony; Tacey Kristina; Toombs Timothy A; Kwok Shirley; Catanese Joseph; White Thomas J; Maxwell Taylor J; Hollingworth Paul; Abraham Richard; Rubinsztein David C; Brayne Carol; Wavrant-De Vrièze Fabienne; Hardy John; O'Donovan Michael; Lovestone Simon; Morris John C; Thal Leon J; Owen Michael; Williams Julie; Goate Alison
DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.
Human molecular genetics 2006;15(17):2560-8.
2006: Thal Leon J
Prevention of Alzheimer disease.
Alzheimer disease and associated disorders 2006;20(3 Suppl 2):S97-9.
2006: Thal Leon J; Kawas Claudia; Galasko Douglas; Salmon David P; Sundsmo Mary P
Robert Katzman honored.
Alzheimer disease and associated disorders 2006;20(3 Suppl 2):S27-8.
2006: Thal Leon J
Toward optimal health: Leon J. Thal, M.D. discusses the latest in Alzheimer's disease in women. Interview by Jodi R. Godfrey.
Journal of women's health (2002) 2006;15(6):704-8.
2006: Yaari Roy; Fleisher Adam S; Gamst Anthony C; Bagwell Victor P; Thal Leon J
Utility of the telephone interview for cognitive status for enrollment in clinical trials.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(2):104-9.
2006: Elson Joanna L; Herrnstadt Corinna; Preston Gwen; Thal Leon; Morris Christopher M; Edwardson J A; Beal M Flint; Turnbull Douglass M; Howell Neil
Does the mitochondrial genome play a role in the etiology of Alzheimer's disease?
Human genetics 2006;119(3):241-54.
2006: Tiraboschi Pietro; Salmon David P; Hansen Lawrence A; Hofstetter Richard C; Thal Leon J; Corey-Bloom Jody
What best differentiates Lewy body from Alzheimer's disease in early-stage dementia?
Brain : a journal of neurology 2006;129(Pt 3):729-35.
2006: Frielingsdorf Helena; Thal Leon J; Pizzo Donald P
The septohippocampal cholinergic system and spatial working memory in the Morris water maze.
Behavioural brain research 2006;168(1):37-46.
2006: Webster Brian; Hansen Lawrence; Adame Anthony; Crews Leslie; Torrance Magdalena; Thal Leon; Masliah Eliezer
Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease.
Journal of neuropathology and experimental neurology 2006;65(2):142-51.
2006: Thal Leon J; Kantarci Kejal; Reiman Eric M; Klunk William E; Weiner Michael W; Zetterberg Henrik; Galasko Douglas; Praticò Domenico; Griffin Sue; Schenk Dale; Siemers Eric
The role of biomarkers in clinical trials for Alzheimer disease.
Alzheimer disease and associated disorders 2006;20(1):6-15.
2006: Grupe Andrew; Li Yonghong; Rowland Charles; Nowotny Petra; Hinrichs Anthony L; Smemo Scott; Kauwe John S K; Maxwell Taylor J; Cherny Sara; Doil Lisa; Tacey Kristina; van Luchene Ryan; Myers Amanda; Wavrant-De Vrièze Fabienne; Kaleem Mona; Hollingworth Paul; Jehu Luke; Foy Catherine; Archer Nicola; Hamilton Gillian; Holmans Peter; Morris Chris M; Catanese Joseph; Sninsky John; White Thomas J; Powell John; Hardy John; O'Donovan Michael; Lovestone Simon; Jones Lesley; Morris John C; Thal Leon; Owen Michael; Williams Julie; Goate Alison
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics 2006;78(1):78-88.
2006: Smemo Scott; Nowotny Petra; Hinrichs Anthony L; Kauwe John S K; Cherny Sara; Erickson Katherine; Myers Amanda J; Kaleem Mona; Marlowe Lauren; Gibson Alison M; Hollingworth Paul; O'Donovan Michael C; Morris Chris M; Holmans Peter; Lovestone Simon; Morris John C; Thal Leon; Li Yonghong; Grupe Andrew; Hardy John; Owen Michael J; Williams Julie; Goate Alison
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of neurology 2006;59(1):21-6.
2006: Pizzo Donald P; Coufal Nicole G; Lortie Mark J; Gage Fred H; Thal Leon J
Regulatable acetylcholine-producing fibroblasts enhance cognitive performance.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(1):175-82.
2005: Fleisher Adam S; Houston Wes S; Eyler Lisa T; Frye Susan; Jenkins Cecily; Thal Leon J; Bondi Mark W
Identification of Alzheimer disease risk by functional magnetic resonance imaging.
Archives of neurology 2005;62(12):1881-8.
2005: Mueller Susanne G; Weiner Michael W; Thal Leon J; Petersen Ronald C; Jack Clifford; Jagust William; Trojanowski John Q; Toga Arthur W; Beckett Laurel
The Alzheimer's disease neuroimaging initiative.
Neuroimaging clinics of North America 2005;15(4):869-77, xi-xii.
2005: Tariot Pierre N; Raman Rema; Jakimovich Laura; Schneider Lon; Porsteinsson Anton; Thomas Ronald; Mintzer Jacobo; Brenner Ronald; Schafer Kim; Thal Leon;
Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(11):942-9.
2005: Olichney J M; Murphy C; Hofstetter C R; Foster K; Hansen L A; Thal L J; Katzman R
Anosmia is very common in the Lewy body variant of Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2005;76(10):1342-7.
2005: Wu Chuang-Kuo; Thal Leon; Pizzo Donald; Hansen Lawrance; Masliah Eliezer; Geula Changiz
Apoptotic signals within the basal forebrain cholinergic neurons in Alzheimer's disease.
Experimental neurology 2005;195(2):484-96.
2005: Li Y; Rowland C; Tacey K; Catanese J; Sninsky J; Hardy J; Powell J; Lovestone S; Morris J C; Thal L; Goate A; Owen M; Williams J; Grupe A
The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples.
Molecular psychiatry 2005;10(9):809-10.
2005: Thal Leon J
Reminiscences: robert katzman and robert terry.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2005;1(1):73.
2005: Mueller Susanne G; Weiner Michael W; Thal Leon J; Petersen Ronald C; Jack Clifford R; Jagust William; Trojanowski John Q; Toga Arthur W; Beckett Laurel
Ways toward an early diagnosis in Alzheimer's disease: The Alzheimer's Disease Neuroimaging Initiative (ADNI).
Alzheimer's & dementia : the journal of the Alzheimer's Association 2005;1(1):55-66.
2005: Palmer Barton W; Dunn Laura B; Appelbaum Paul S; Mudaliar Sunder; Thal Leon; Henry Robert; Golshan Shahrokh; Jeste Dilip V
Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer disease, or diabetes mellitus: comparison of a 3-item questionnaire with a comprehensive standardized capacity instrument.
Archives of general psychiatry 2005;62(7):726-33.
2005: Nowotny Petra; Hinrichs Anthony L; Smemo Scott; Kauwe John S K; Maxwell Taylor; Holmans Peter; Hamshere Marian; Turic Dragana; Jehu Luke; Hollingworth Paul; Moore Pamela; Bryden Leslie; Myers Amanda; Doil Lisa M; Tacey Kristina M; Gibson Alison M; McKeith Ian G; Perry Robert H; Morris Chris M; Thal Leon; Morris John C; O'Donovan Michael C; Lovestone Simon; Grupe Andrew; Hardy John; Owen Michael J; Williams Julie; Goate Alison
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Fleisher Adam; Grundman Michael; Jack Clifford R; Petersen Ronald C; Taylor Curtis; Kim Hyun T; Schiller Denise H B; Bagwell Victor; Sencakova Drahomira; Weiner Myron F; DeCarli Charles; DeKosky Steven T; van Dyck Christopher H; Thal Leon J;
Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment.
Archives of neurology 2005;62(6):953-7.
2005: Petersen Ronald C; Thomas Ronald G; Grundman Michael; Bennett David; Doody Rachelle; Ferris Steven; Galasko Douglas; Jin Shelia; Kaye Jeffrey; Levey Allan; Pfeiffer Eric; Sano Mary; van Dyck Christopher H; Thal Leon J;
Vitamin E and donepezil for the treatment of mild cognitive impairment.
The New England journal of medicine 2005;352(23):2379-88.
2005: Thal Leon J; Ferris Steven H; Kirby Louis; Block Gilbert A; Lines Christopher R; Yuen Eric; Assaid Christopher; Nessly Michael L; Norman Barbara A; Baranak Christine C; Reines Scott A;
A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(6):1204-15.
2005: Tuszynski Mark H; Thal Leon; Pay Mary; Salmon David P; U Hoi Sang; Bakay Roy; Patel Piyush; Blesch Armin; Vahlsing H Lee; Ho Gilbert; Tong Gang; Potkin Steven G; Fallon James; Hansen Lawrence; Mufson Elliott J; Kordower Jeffrey H; Gall Christine; Conner James
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease.
Nature medicine 2005;11(5):551-5.
2005: Ho Gilbert J; Hashimoto Makoto; Adame Anthony; Izu Matthew; Alford Michael F; Thal Leon J; Hansen Lawrence A; Masliah Eliezer
Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role.
Neurobiology of aging 2005;26(5):625-35.
2005: Sabbagh M N; Tyas S L; Emery S C; Hansen L A; Alford M F; Reid R T; Tiraboschi P; Thal L J
Smoking affects the phenotype of Alzheimer disease.
Neurology 2005;64(7):1301-3.
2005: Li Yonghong; Hollingworth Paul; Moore Pamela; Foy Catherine; Archer Nicola; Powell John; Nowotny Petra; Holmans Peter; O'Donovan Michael; Tacey Kristina; Doil Lisa; van Luchene Ryan; Garcia Veronica; Rowland Charles; Lau Kit; Cantanese Joseph; Sninsky John; Hardy John; Thal Leon; Morris John C; Goate Alison; Lovestone Simon; Owen Michael; Williams Julie; Grupe Andrew
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Human mutation 2005;25(3):270-7.
2005: Gozes Illana; Morimoto Bruce H; Tiong Jacqueline; Fox Anthony; Sutherland Karole; Dangoor David; Holser-Cochav Miriam; Vered Karin; Newton Paul; Aisen Paul S; Matsuoka Yasuji; van Dyck Christopher H; Thal Leon
NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP).
CNS drug reviews 2005;11(4):353-68.
2005: Tractenberg Rochelle E; Weiner Myron F; Cummings Jeffrey L; Patterson Marian B; Thal Leon J
Independence of changes in behavior from cognition and function in community-dwelling persons with Alzheimer's disease: a factor analytic approach.
The Journal of neuropsychiatry and clinical neurosciences 2005;17(1):51-60.
2004: Cummings Jeffrey L; Tractenberg Rochelle E; Gamst Anthony; Teri Linda; Masterman Donna; Thal Leon J
Regression to the mean: implications for clinical trials of psychotropic agents in dementia.
Current Alzheimer research 2004;1(4):323-8.
2004: Li Yonghong; Nowotny Petra; Holmans Peter; Smemo Scott; Kauwe John S K; Hinrichs Anthony L; Tacey Kristina; Doil Lisa; van Luchene Ryan; Garcia Veronica; Rowland Charles; Schrodi Steve; Leong Diane; Gogic Goran; Chan Joanne; Cravchik Anibal; Ross David; Lau Kit; Kwok Shirley; Chang Sheng-Yung; Catanese Joe; Sninsky John; White Thomas J; Hardy John; Powell John; Lovestone Simon; Morris John C; Thal Leon; Owen Michael; Williams Julie; Goate Alison; Grupe Andrew
Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15688-93.
2004: Schafer Kimberly A; Tractenberg Rochelle E; Sano Mary; Mackell Joan A; Thomas Ronald G; Gamst Anthony; Thal Leon J; Morris John C;
Reliability of monitoring the clinical dementia rating in multicenter clinical trials.
Alzheimer disease and associated disorders 2004;18(4):219-22.
2004: Thal Leon J
The Alzheimer's Disease Cooperative Study in 2004.
Alzheimer disease and associated disorders 2004;18(4):183-5.
2004: Hamilton Joanne M; Salmon David P; Galasko Douglas; Delis Dean C; Hansen Lawrence A; Masliah Eliezer; Thomas Ronald G; Thal Leon J
A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease.
Journal of the International Neuropsychological Society : JINS 2004;10(5):689-97.
2004: Li Yonghong; Tacey Kristina; Doil Lisa; van Luchene Ryan; Garcia Veronica; Rowland Charles; Schrodi Steve; Leong Diane; Lau Kit; Catanese Joe; Sninsky John; Nowotny Petra; Holmans Peter; Hardy John; Powell John; Lovestone Simon; Thal Leon; Owen Michael; Williams Julie; Goate Alison; Grupe Andrew
Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.
Neuroscience letters 2004;366(3):268-71.
2004: Pizzo Donald P; Paban Veronique; Coufal Nicole G; Gage Fred H; Thal Leon J
Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector.
Brain research. Molecular brain research 2004;126(1):1-13.
2004: Shumaker Sally A; Legault Claudine; Kuller Lewis; Rapp Stephen R; Thal Leon; Lane Dorothy S; Fillit Howard; Stefanick Marcia L; Hendrix Susan L; Lewis Cora E; Masaki Kamal; Coker Laura H;
Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study.
JAMA : the journal of the American Medical Association 2004;291(24):2947-58.
2004: Brandon Eugene P; Mellott Tiffany; Pizzo Donald P; Coufal Nicole; D'Amour Kevin A; Gobeske Kevin; Lortie Mark; López-Coviella Ignacio; Berse Brygida; Thal Leon J; Gage Fred H; Blusztajn Jan Krzysztof
Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(24):5459-66.
2004: Tiraboschi P; Hansen L A; Thal L J; Corey-Bloom J
The importance of neuritic plaques and tangles to the development and evolution of AD.
Neurology 2004;62(11):1984-9.
2004: Tiraboschi P; Hansen L A; Masliah E; Alford M; Thal L J; Corey-Bloom J
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease.
Neurology 2004;62(11):1977-83.
2004: Swanberg Margaret M; Tractenberg Rochelle E; Mohs Richard; Thal Leon J; Cummings Jeffrey L
Executive dysfunction in Alzheimer disease.
Archives of neurology 2004;61(4):556-60.
2004: Tiraboschi P; Sabbagh M N; Hansen L A; Salmon D P; Merdes A; Gamst A; Masliah E; Alford M; Thal L J; Corey-Bloom J
Alzheimer disease without neocortical neurofibrillary tangles: "a second look".
Neurology 2004;62(7):1141-7.
2004: Grundman Michael; Petersen Ronald C; Ferris Steven H; Thomas Ronald G; Aisen Paul S; Bennett David A; Foster Norman L; Jack Clifford R; Galasko Douglas R; Doody Rachelle; Kaye Jeffrey; Sano Mary; Mohs Richard; Gauthier Serge; Kim Hyun T; Jin Shelia; Schultz Arlan N; Schafer Kimberly; Mulnard Ruth; van Dyck Christopher H; Mintzer Jacobo; Zamrini Edward Y; Cahn-Weiner Deborah; Thal Leon J;
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
Archives of neurology 2004;61(1):59-66.
2004: Licastro F; Chiappelli M; Thal L J; Masliah E
alpha-1-Antichymotrypsin polymorphism in the gene promoter region affects survival and synapsis loss in Alzheimer's disease.
Archives of gerontology and geriatrics. Supplement 2004;(9):243-51.
2004: Pizzo D P; Thal L J
Intraparenchymal nerve growth factor improves behavioral deficits while minimizing the adverse effects of intracerebroventricular delivery.
Neuroscience 2004;124(4):743-55.
2003: Thal L J; Grundman M; Berg J; Ernstrom K; Margolin R; Pfeiffer E; Weiner M F; Zamrini E; Thomas R G
Idebenone treatment fails to slow cognitive decline in Alzheimer's disease.
Neurology 2003;61(11):1498-502.
2003: Tractenberg Rochelle E; Singer Clifford M; Cummings Jeffrey L; Thal Leon J
The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease.
Journal of sleep research 2003;12(4):331-7.
2003: Singer Clifford; Tractenberg Rochelle E; Kaye Jeffrey; Schafer Kim; Gamst Anthony; Grundman Michael; Thomas Ronald; Thal Leon J;
A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease.
Sleep 2003;26(7):893-901.
2003: Caligiuri M P; Peavy G; Salmon D P; Galasko D R; Thal L J
Neuromotor abnormalities and risk for psychosis in Alzheimer's disease.
Neurology 2003;61(7):954-8.
2003: Bondi Mark W; Houston Wes S; Salmon David P; Corey-Bloom Jody; Katzman Robert; Thal Leon J; Delis Dean C
Neuropsychological deficits associated with Alzheimer's disease in the very-old: discrepancies in raw vs. standardized scores.
Journal of the International Neuropsychological Society : JINS 2003;9(5):783-95.
2003: Masliah E; Alford M; Adame A; Rockenstein E; Galasko D; Salmon D; Hansen L A; Thal L J
Abeta1-42 promotes cholinergic sprouting in patients with AD and Lewy body variant of AD.
Neurology 2003;61(2):206-11.
2003: Pappolla M A; Bryant-Thomas T K; Herbert D; Pacheco J; Fabra Garcia M; Manjon M; Girones X; Henry T L; Matsubara E; Zambon D; Wolozin B; Sano M; Cruz-Sanchez F F; Thal L J; Petanceska S S; Refolo L M
Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology.
Neurology 2003;61(2):199-205.
2003: Kennedy B P; Ziegler M G; Alford M; Hansen L A; Thal L J; Masliah E
Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2003;110(7):789-801.
2003: Tractenberg Rochelle E; Weiner Myron F; Patterson Marian B; Teri Linda; Thal Leon J
Comorbidity of psychopathological domains in community-dwelling persons with Alzheimer's disease.
Journal of geriatric psychiatry and neurology 2003;16(2):94-9.
2003: Aisen Paul S; Schafer Kimberly A; Grundman Michael; Pfeiffer Eric; Sano Mary; Davis Kenneth L; Farlow Martin R; Jin Shelia; Thomas Ronald G; Thal Leon J;
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2003;289(21):2819-26.
2003: Grundman M; Capparelli E; Kim H T; Morris J C; Farlow M; Rubin E H; Heidebrink J; Hake A; Ho G; Schultz A N; Schafer K; Houston W; Thomas R; Thal L J;
A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients.
Life sciences 2003;73(5):539-53.
2003: Merdes A R; Hansen L A; Jeste D V; Galasko D; Hofstetter C R; Ho G J; Thal L J; Corey-Bloom J
Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies.
Neurology 2003;60(10):1586-90.
2003: Shumaker Sally A; Legault Claudine; Rapp Stephen R; Thal Leon; Wallace Robert B; Ockene Judith K; Hendrix Susan L; Jones Beverly N; Assaf Annlouise R; Jackson Rebecca D; Kotchen Jane Morley; Wassertheil-Smoller Sylvia; Wactawski-Wende Jean;
Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2003;289(20):2651-62.
2003: Aisen Paul S; Schafer Kimberly; Grundman Michael; Thomas Ronald; Thal Leon J
NSAIDs and hypertension.
Archives of internal medicine 2003;163(9):1115; author reply 1115-6.
2003: Thal Leon J
Therapeutics and mild cognitive impairment: current status and future directions.
Alzheimer disease and associated disorders 2003;17 Suppl 2():S69-71.
2003: Montgomery Stuart A; Thal L J; Amrein R
Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease.
International clinical psychopharmacology 2003;18(2):61-71.
2003: Thal Leon J; Thomas Ronald G; Mulnard Ruth; Sano Mary; Grundman Michael; Schneider Lon
Estrogen levels do not correlate with improvement in cognition.
Archives of neurology 2003;60(2):209-12.
2003: Brandon Eugene P; Lin Weichun; D'Amour Kevin A; Pizzo Donald P; Dominguez Bertha; Sugiura Yoshie; Thode Silke; Ko Chien-Ping; Thal Leon J; Gage Fred H; Lee Kuo-Fen
Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(2):539-49.
2003: Aisen P S; Berg J D; Craft S; Peskind E R; Sano M; Teri L; Mulnard R A; Thomas R G; Thal L J
Steroid-induced elevation of glucose in Alzheimer's disease: relationship to gender, apolipoprotein E genotype and cognition.
Psychoneuroendocrinology 2003;28(1):113-20.
2003: Grundman Michael; Jack Clifford R; Petersen Ronald C; Kim Hyun T; Taylor Curtis; Datvian Marina; Weiner Myron F; DeCarli Charles; DeKosky Steven T; van Dyck Christopher; Darvesh Sultan; Yaffe Kristine; Kaye Jeffrey; Ferris Steven H; Thomas Ronald G; Thal Leon J;
Hippocampal volume is associated with memory but not monmemory cognitive performance in patients with mild cognitive impairment.
Journal of molecular neuroscience : MN 2003;20(3):241-8.
2003: Palmer Barton W; Bondi Mark W; Twamley Elizabeth W; Thal Leon; Golshan Shahrokh; Jeste Dilip V
Are late-onset schizophrenia spectrum disorders neurodegenerative conditions? Annual rates of change on two dementia measures.
The Journal of neuropsychiatry and clinical neurosciences 2003;15(1):45-52.
2002: Tuszynski Mark H; U Hoi Sang; Alksne John; Bakay Roy A; Pay Mary Margaret; Merrill David; Thal Leon J
Growth factor gene therapy for Alzheimer disease.
Neurosurgical focus 2002;13(5):e5.
2002: Pizzo Donald P; Winkler Jürgen; Sidiqi Ibrahim; Waite Jerene J; Thal Leon J
Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration.
Experimental neurology 2002;178(1):91-103.
2002: Lange Kelly L; Bondi Mark W; Salmon David P; Galasko Douglas; Delis Dean C; Thomas Ronald G; Thal Leon J
Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype.
Journal of the International Neuropsychological Society : JINS 2002;8(7):943-55.
2002: Ho Gilbert J; Hansen Lawrence A; Alford Michael F; Foster Katherine; Salmon David P; Galasko Douglas; Thal Leon J; Masliah Eliezer
Age at onset is associated with disease severity in Lewy body variant and Alzheimer's disease.
Neuroreport 2002;13(14):1825-8.
2002: Salmon D P; Thomas R G; Pay M M; Booth A; Hofstetter C R; Thal L J; Katzman R
Alzheimer's disease can be accurately diagnosed in very mildly impaired individuals.
Neurology 2002;59(7):1022-8.
2002: Tiraboschi Pietro; Hansen Larry A; Alford Michael; Merdes Annette; Masliah Eliezer; Thal Leon J; Corey-Bloom Jody
Early and widespread cholinergic losses differentiate dementia with Lewy bodies from Alzheimer disease.
Archives of general psychiatry 2002;59(10):946-51.
2002: Olichney J M; Morris S K; Ochoa C; Salmon D P; Thal L J; Kutas M; Iragui V J
Abnormal verbal event related potentials in mild cognitive impairment and incipient Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(4):377-84.
2002: Pizzo Donald P; Thal Leon J; Winkler Jürgen
Mnemonic deficits in animals depend upon the degree of cholinergic deficit and task complexity.
Experimental neurology 2002;177(1):292-305.
2002: Grundman Michael; Sencakova Drahomira; Jack Clifford R; Petersen Ronald C; Kim Hyun T; Schultz Arlan; Weiner Myron F; DeCarli Charles; DeKosky Steven T; van Dyck Christopher; Thomas Ronald G; Thal Leon J;
Brain MRI hippocampal volume and prediction of clinical status in a mild cognitive impairment trial.
Journal of molecular neuroscience : MN 2002;19(1-2):23-7.
2002: Tuszynski Mark H; Thal Leon; U Hoi-Sang; Pay Mary Margaret; Blesch Armin; Conner James; Vahlsing H Lee
Nerve growth factor gene therapy for Alzheimer's disease.
Journal of molecular neuroscience : MN 2002;19(1-2):207.
2002: Pappolla Miguel A; Smith Mark A; Bryant-Thomas Tara; Bazan Nicolas; Petanceska Suzana; Perry George; Thal Leon J; Sano Mary; Refolo Lorenzo M
Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis.
Free radical biology & medicine 2002;33(2):173-81.
2002: Rascovsky K; Salmon D P; Ho G J; Galasko D; Peavy G M; Hansen L A; Thal L J
Cognitive profiles differ in autopsy-confirmed frontotemporal dementia and AD.
Neurology 2002;58(12):1801-8.
2002: Grundman Michael; Farlow Martin; Peavy Guerry; Kim Hyun T; Capparelli Edmund; Schultz Arlan N; Salmon David P; Ferris Steven H; Mobs Richard; Thomas Ronald G; Schafer Kimberly; Campbell Karen; Hake Ann Marie; Schoos Barbara; Thal Leon J;
A phase I study of AIT-082 in healthy elderly volunteers.
Journal of molecular neuroscience : MN 2002;18(3):283-93.
2002: Thal Leon J
How to define treatment success using cholinesterase inhibitors.
International journal of geriatric psychiatry 2002;17(4):388-90.
2002: Power Ann E; Thal Leon J; McGaugh James L
Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2315-9.
2002: Galasko D; Salmon D P; Craig U-K; Thal L J; Schellenberg G; Wiederholt W
Clinical features and changing patterns of neurodegenerative disorders on Guam, 1997-2000.
Neurology 2002;58(1):90-7.
2002: Weiner Myron F; Tractenberg Rochelle E; Jin Shelia; Gamst Anthony; Thomas Ronald G; Koss Elisabeth; Thal Leon J
Assessing Alzheimer's disease patients with the Cohen-Mansfield Agitation Inventory: scoring and clinical implications.
Journal of psychiatric research 2002;36(1):19-25.
2002: Tractenberg Rochelle E; Gamst Anthony; Thomas Ronald G; Patterson Marian; Schneider Lon S; Thal Leon J
Investigating emergent symptomatology as an outcome measure in a behavioral study of Alzheimer's disease.
The Journal of neuropsychiatry and clinical neurosciences 2002;14(3):303-10.
2002: Weiner Myron F; Tractenberg Rochelle E; Sano Mary; Logsdon Rebecca; Teri Linda; Galasko Douglas; Gamst Anthony; Thomas Ron; Thal Leon J
No long-term effect of behavioral treatment on psychotropic drug use for agitation in Alzheimer's disease patients.
Journal of geriatric psychiatry and neurology 2002;15(2):95-8.
2002: Tractenberg Rochelle E; Weiner Myron F; Patterson Marian B; Gamst Anthony; Thal Leon J
Emergent psychopathology in Alzheimer's disease patients over 12 months associated with functional, not cognitive, changes.
Journal of geriatric psychiatry and neurology 2002;15(2):110-7.
2002: Tractenberg Rochelle E; Weiner Myron F; Thal Leon J
Estimating the prevalence of agitation in community-dwelling persons with Alzheimer's disease.
The Journal of neuropsychiatry and clinical neurosciences 2002;14(1):11-8.
2001: Masliah E; Alford M; Galasko D; Salmon D; Hansen L A; Good P F; Perl D P; Thal L
Cholinergic deficits in the brains of patients with parkinsonism-dementia complex of Guam.
Neuroreport 2001;12(18):3901-3.
2001: Petersen R C; Doody R; Kurz A; Mohs R C; Morris J C; Rabins P V; Ritchie K; Rossor M; Thal L; Winblad B
Current concepts in mild cognitive impairment.
Archives of neurology 2001;58(12):1985-92.
2001: Tractenberg R E; Gamst A; Weiner M F; Koss E; Thomas R G; Teri L; Thal L
Frequency of behavioral symptoms characterizes agitation in Alzheimer's disease.
International journal of geriatric psychiatry 2001;16(9):886-91.
2001: Doody R S; Stevens J C; Beck C; Dubinsky R M; Kaye J A; Gwyther L; Mohs R C; Thal L J; Whitehouse P J; DeKosky S T; Cummings J L
Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology.
Neurology 2001;56(9):1154-66.
2001: Sabbagh M N; Reid R T; Hansen L A; Alford M; Thal L J
Correlation of nicotinic receptor binding with clinical and neuropathological changes in Alzheimer's disease and dementia with Lewy bodies.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(10):1149-57.
2001: Reid R T; Sabbagh M N; Thal L J
Does apolipoprotein E (Apo-E) genotype influence nicotinic receptor binding in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(8-9):1043-50.
2000: Sabbagh M N; Galasko D; Koo E; Thal L J
Amyloid-beta and treatment opportunities for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2000;2(3-4):231-59.
2000: Paulsen J S; Ready R E; Stout J C; Salmon D P; Thal L J; Grant I; Jeste D V
Neurobehaviors and psychotic symptoms in Alzheimer's disease.
Journal of the International Neuropsychological Society : JINS 2000;6(7):815-20.
2000: Tiraboschi P; Hansen L A; Alford M; Masliah E; Thal L J; Corey-Bloom J
The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease.
Neurology 2000;55(9):1278-83.
2000: Teri L; Logsdon R G; Peskind E; Raskind M; Weiner M F; Tractenberg R E; Foster N L; Schneider L S; Sano M; Whitehouse P; Tariot P; Mellow A M; Auchus A P; Grundman M; Thomas R G; Schafer K; Thal L J;
Treatment of agitation in AD: a randomized, placebo-controlled clinical trial.
Neurology 2000;55(9):1271-8.
2000: Tractenberg R E; Jin S; Patterson M; Schneider L S; Gamst A; Thomas R G; Thal L J
Qualifying change: a method for defining clinically meaningful outcomes of change score computation.
Journal of the American Geriatrics Society 2000;48(11):1478-82.
2000: Grundman M; Thal L J
Treatment of Alzheimer's disease: rationale and strategies.
Neurologic clinics 2000;18(4):807-28.
2000: Lee J H; Olichney J M; Hansen L A; Hofstetter C R; Thal L J
Small concomitant vascular lesions do not influence rates of cognitive decline in patients with Alzheimer disease.
Archives of neurology 2000;57(10):1474-9.
2000: Rei R T; Sabbagh M N; Corey-Bloom J; Tiraboschi P; Thal L J
Nicotinic receptor losses in dementia with Lewy bodies: comparisons with Alzheimer's disease.
Neurobiology of aging 2000;21(5):741-6.
2000: Thal L J; Calvani M; Amato A; Carta A
A 1-year controlled trial of acetyl-l-carnitine in early-onset AD.
Neurology 2000;55(6):805-10.
2000: Olichney J M; Hansen L A; Hofstetter C R; Lee J H; Katzman R; Thal L J
Association between severe cerebral amyloid angiopathy and cerebrovascular lesions in Alzheimer disease is not a spurious one attributable to apolipoprotein E4.
Archives of neurology 2000;57(6):869-74.
2000: Thomas R G; Berg J D; Sano M; Thal L
Analysis of longitudinal data in an Alzheimer's disease clinical trial.
Statistics in medicine 2000;19(11-12):1433-40.
2000: Thal L J
Anti-inflammatory drugs and Alzheimer's disease.
Neurobiology of aging 2000;21(3):449-50; discussion 451-3.
2000: Paulsen J S; Salmon D P; Thal L J; Romero R; Weisstein-Jenkins C; Galasko D; Hofstetter C R; Thomas R; Grant I; Jeste D V
Incidence of and risk factors for hallucinations and delusions in patients with probable AD.
Neurology 2000;54(10):1965-71.
2000: Olichney J M; Hansen L A; Lee J H; Hofstetter C R; Katzman R; Thal L J
Relationship between severe amyloid angiopathy, apolipoprotein E genotype, and vascular lesions in Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;903():138-43.
2000: Bayley P J; Salmon D P; Bondi M W; Bui B K; Olichney J; Delis D C; Thomas R G; Thal L J
Comparison of the serial position effect in very mild Alzheimer's disease, mild Alzheimer's disease, and amnesia associated with electroconvulsive therapy.
Journal of the International Neuropsychological Society : JINS 2000;6(3):290-8.
2000: Weiner M F; Tractenberg R; Teri L; Logsdon R; Thomas R G; Gamst A; Thal L J
Quantifying behavioral disturbance in Alzheimer's disease patients.
Journal of psychiatric research 2000;34(2):163-7.
2000: Hohl U; Tiraboschi P; Hansen L A; Thal L J; Corey-Bloom J
Diagnostic accuracy of dementia with Lewy bodies.
Archives of neurology 2000;57(3):347-51.
2000: Horner P J; Power A E; Kempermann G; Kuhn H G; Palmer T D; Winkler J; Thal L J; Gage F H
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(6):2218-28.
2000: Mulnard R A; Cotman C W; Kawas C; van Dyck C H; Sano M; Doody R; Koss E; Pfeiffer E; Jin S; Gamst A; Grundman M; Thomas R; Thal L J
Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study.
JAMA : the journal of the American Medical Association 2000;283(8):1007-15.
2000: Aisen P S; Davis K L; Berg J D; Schafer K; Campbell K; Thomas R G; Weiner M F; Farlow M R; Sano M; Grundman M; Thal L J
A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study.
Neurology 2000;54(3):588-93.
2000: Pappas B A; Bayley P J; Bui B K; Hansen L A; Thal L J
Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients.
Neurobiology of aging 2000;21(1):11-7.
2000: Thal L J; Forrest M; Loft H; Mengel H
Lu 25-109, a muscarinic agonist, fails to improve cognition in Alzheimer's disease. Lu25-109 Study Group.
Neurology 2000;54(2):421-6.
2000: Tiraboschi P; Hansen L A; Alford M; Sabbagh M N; Schoos B; Masliah E; Thal L J; Corey-Bloom J
Cholinergic dysfunction in diseases with Lewy bodies.
Neurology 2000;54(2):407-11.
2000: Corey-Bloom J; Tiraboschi P; Hansen L A; Alford M; Schoos B; Sabbagh M N; Masliah E; Thal L J
E4 allele dosage does not predict cholinergic activity or synapse loss in Alzheimer's disease.
Neurology 2000;54(2):403-6.
2000: Winkler J; Ramirez G A; Thal L J; Waite J J
Nerve growth factor (NGF) augments cortical and hippocampal cholinergic functioning after p75NGF receptor-mediated deafferentation but impairs inhibitory avoidance and induces fear-related behaviors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(2):834-44.
2000: Licastro F; Masliah E; Pedrini S; Thal L J
Blood levels of alpha-1-antichymotrypsin and risk factors for Alzheimer's disease: effects of gender and apolipoprotein E genotype.
Dementia and geriatric cognitive disorders 2000;11(1):25-8.
2000: Tractenberg R E; Patterson M; Weiner M F; Teri L; Grundman M; Thomas R G; Thal L J
Prevalence of symptoms on the CERAD behavior rating scale for dementia in normal elderly subjects and Alzheimer's disease patients.
The Journal of neuropsychiatry and clinical neurosciences 2000;12(4):472-9.
2000: Thal L J
Trials to slow progression and prevent disease onset.
Journal of neural transmission. Supplementum 2000;59():243-9.
1999: Sabbagh M N; Corey-Bloom J; Tiraboschi P; Thomas R; Masliah E; Thal L J
Neurochemical markers do not correlate with cognitive decline in the Lewy body variant of Alzheimer disease.
Archives of neurology 1999;56(12):1458-61.
1999: Logsdon R G; Teri L; Weiner M F; Gibbons L E; Raskind M; Peskind E; Grundman M; Koss E; Thomas R G; Thal L J
Assessment of agitation in Alzheimer's disease: the agitated behavior in dementia scale. Alzheimer's Disease Cooperative Study.
Journal of the American Geriatrics Society 1999;47(11):1354-8.
1999: Pizzo D P; Waite J J; Thal L J; Winkler J
Intraparenchymal infusions of 192 IgG-saporin: development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei.
Journal of neuroscience methods 1999;91(1-2):9-19.
1999: Kawas C H; Clark C M; Farlow M R; Knopman D S; Marson D; Morris J C; Thal L J; Whitehouse P J
Clinical trials in Alzheimer disease: debate on the use of placebo controls.
Alzheimer disease and associated disorders 1999;13(3):124-9.
1999: Bondi M W; Salmon D P; Galasko D; Thomas R G; Thal L J
Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease.
Psychology and aging 1999;14(2):295-303.
1999: Hohl U; Grundman M; Salmon D P; Thomas R G; Thal L J
Mini-Mental State Examination and Mattis Dementia Rating Scale performance differs in Hispanic and non-Hispanic Alzheimer's disease patients.
Journal of the International Neuropsychological Society : JINS 1999;5(4):301-7.
1999: Thal L J; Ferguson J M; Mintzer J; Raskin A; Targum S D
A 24-week randomized trial of controlled-release physostigmine in patients with Alzheimer's disease.
Neurology 1999;52(6):1146-52.
1999: Knopman D S; Berg J D; Thomas R; Grundman M; Thal L J; Sano M
Nursing home placement is related to dementia progression: experience from a clinical trial. Alzheimer's Disease Cooperative Study.
Neurology 1999;52(4):714-8.
1999: Imbimbo B P; Martelli P; Troetel W M; Lucchelli F; Lucca U; Thal L J
Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease.
Neurology 1999;52(4):700-8.
1998: Imbimbo B P; Lucca U; Lucchelli F; Alberoni M; Thal L J
A 25-week placebo-controlled study of eptastigmine in patients with Alzheimer disease.
Alzheimer disease and associated disorders 1998;12(4):313-22.
1998: Whitehouse P J; Kittner B; Roessner M; Rossor M; Sano M; Thal L; Winblad B
Clinical trial designs for demonstrating disease-course-altering effects in dementia.
Alzheimer disease and associated disorders 1998;12(4):281-94.
1998: Weiner M F; Koss E; Patterson M; Jin S; Teri L; Thomas R; Thal L J; Whitehouse P
A comparison of the Cohen-Mansfield agitation inventory with the CERAD behavioral rating scale for dementia in community-dwelling persons with Alzheimer's disease.
Journal of psychiatric research 1998;32(6):347-51.
1998: Olichney J M; Galasko D; Salmon D P; Hofstetter C R; Hansen L A; Katzman R; Thal L J
Cognitive decline is faster in Lewy body variant than in Alzheimer's disease.
Neurology 1998;51(2):351-7.
1998: Conrad C; Amano N; Andreadis A; Xia Y; Namekataf K; Oyama F; Ikeda K; Wakabayashi K; Takahashi H; Thal L J; Katzman R; Shackelford D A; Matsushita M; Masliah E; Sawa A
Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy.
Neuroscience letters 1998;250(2):135-7.
1998: Winkler J; Thal L J; Gage F H; Fisher L J
Cholinergic strategies for Alzheimer's disease.
Journal of molecular medicine (Berlin, Germany) 1998;76(8):555-67.
1998: Connor D J; Salmon D P; Sandy T J; Galasko D; Hansen L A; Thal L J
Cognitive profiles of autopsy-confirmed Lewy body variant vs pure Alzheimer disease.
Archives of neurology 1998;55(7):994-1000.
1998: Hsu L J; Mallory M; Xia Y; Veinbergs I; Hashimoto M; Yoshimoto M; Thal L J; Saitoh T; Masliah E
Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development.
Journal of neurochemistry 1998;71(1):338-44.
1998: Tanaka S; Chen X; Xia Y; Kang D E; Matoh N; Sundsmo M; Thomas R G; Katzman R; Thal L J; Trojanowski J Q; Saitoh T; Ueda K; Masliah E
Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease.
Neurology 1998;50(6):1556-62.
1998: Winkler J; Power A E; Ramirez G A; Thal L J
Short-term and complete reversal of NGF effects in rats with lesions of the nucleus basalis magnocellularis.
Brain research 1998;788(1-2):1-12.
1998: Ellis R J; Jan K; Kawas C; Koller W C; Lyons K E; Jeste D V; Hansen L A; Thal L J
Diagnostic validity of the dementia questionnaire for Alzheimer disease.
Archives of neurology 1998;55(3):360-5.
1998: Sabbagh M N; Reid R T; Corey-Bloom J; Rao T S; Hansen L A; Alford M; Masliah E; Adem A; Lloyd G K; Thal L J
Correlation of nicotinic binding with neurochemical markers in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(6-7):709-17.
1998: Grundman M; Corey-Bloom J; Thal L J
Perspectives in clinical Alzheimer's disease research and the development of antidementia drugs.
Journal of neural transmission. Supplementum 1998;53():255-75.
1997: Thal L J; Thomas R G; Sano M
Tacrine and nursing home placement.
Neurology 1997;49(3):897-9.
1997: Kuhn H G; Winkler J; Kempermann G; Thal L J; Gage F H
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(15):5820-9.
1997: Crook R; Ellis R; Shanks M; Thal L J; Perez-Tur J; Baker M; Hutton M; Haltia T; Hardy J; Galasko D
Early-onset Alzheimer's disease with a presenilin-1 mutation at the site corresponding to the Volga German presenilin-2 mutation.
Annals of neurology 1997;42(1):124-8.
1997: Olichney J M; Sabbagh M N; Hofstetter C R; Galasko D; Grundman M; Katzman R; Thal L J
The impact of apolipoprotein E4 on cause of death in Alzheimer's disease.
Neurology 1997;49(1):76-81.
1997: Kang D E; Saitoh T; Chen X; Xia Y; Masliah E; Hansen L A; Thomas R G; Thal L J; Katzman R
Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease.
Neurology 1997;49(1):56-61.
1997: Morris J C; Ernesto C; Schafer K; Coats M; Leon S; Sano M; Thal L J; Woodbury P
Clinical dementia rating training and reliability in multicenter studies: the Alzheimer's Disease Cooperative Study experience.
Neurology 1997;48(6):1508-10.
1997: Davis R E; Miller S; Herrnstadt C; Ghosh S S; Fahy E; Shinobu L A; Galasko D; Thal L J; Beal M F; Howell N; Parker W D
Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4526-31.
1997: Sano M; Ernesto C; Thomas R G; Klauber M R; Schafer K; Grundman M; Woodbury P; Growdon J; Cotman C W; Pfeiffer E; Schneider L S; Thal L J
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
The New England journal of medicine 1997;336(17):1216-22.
1997: Ellis R J; Deutsch R; Heaton R K; Marcotte T D; McCutchan J A; Nelson J A; Abramson I; Thal L J; Atkinson J H; Wallace M R; Grant I
Neurocognitive impairment is an independent risk factor for death in HIV infection. San Diego HIV Neurobehavioral Research Center Group.
Archives of neurology 1997;54(4):416-24.
1997: Conrad C; Andreadis A; Trojanowski J Q; Dickson D W; Kang D; Chen X; Wiederholt W; Hansen L; Masliah E; Thal L J; Katzman R; Xia Y; Saitoh T
Genetic evidence for the involvement of tau in progressive supranuclear palsy.
Annals of neurology 1997;41(2):277-81.
1997: Corey-Bloom J; Sabbagh M N; Bondi M W; Hansen L; Alford M F; Masliah E; Thal L J
Hippocampal sclerosis contributes to dementia in the elderly.
Neurology 1997;48(1):154-60.
1997: Winkler J; Ramirez G A; Kuhn H G; Peterson D A; Day-Lollini P A; Stewart G R; Tuszynski M H; Gage F H; Thal L J
Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor.
Annals of neurology 1997;41(1):82-93.
1997: Bodick N; Forette F; Hadler D; Harvey R J; Leber P; McKeith I G; Riekkinen P J; Rossor M N; Scheltens P; Shimohama S; Spiegel R; Tanaka S; Thal L J; Urata Y; Whitehouse P; Wilcock G
Protocols to demonstrate slowing of Alzheimer disease progression. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. The Disease Progression Sub-Group.
Alzheimer disease and associated disorders 1997;11 Suppl 3():50-3.
1997: Thal L J; Carta A; Doody R; Leber P; Mohs R; Schneider L; Shimohama S; Silber C
Prevention protocols for Alzheimer disease. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines.
Alzheimer disease and associated disorders 1997;11 Suppl 3():46-9.
1997: Mackell J A; Ferris S H; Mohs R; Schneider L; Galasko D; Whitehouse P; Schmitt F; Sano M; Thal L J
Multicenter evaluation of new instruments for Alzheimer's disease clinical trials: summary of results. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S65-9.
1997: Sano M; Mackell J A; Ponton M; Ferreira P; Wilson J; Pawluczyk S; Pfeiffer E; Thomas R G; Jin S; Schafer K; Schittini M; Grundman M; Ferris S H; Thal L J
The Spanish Instrument Protocol: design and implementation of a study to evaluate treatment efficacy Instruments for Spanish-speaking patients with Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S57-64.
1997: Schmitt F A; Ashford W; Ernesto C; Saxton J; Schneider L S; Clark C M; Ferris S H; Mackell J A; Schafer K; Thal L J
The severe impairment battery: concurrent validity and the assessment of longitudinal change in Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S51-6.
1997: Koss E; Weiner M; Ernesto C; Cohen-Mansfield J; Ferris S H; Grundman M; Schafer K; Sano M; Thal L J; Thomas R; Whitehouse P J
Assessing patterns of agitation in Alzheimer's disease patients with the Cohen-Mansfield Agitation Inventory. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S45-50.
1997: Mohs R C; Knopman D; Petersen R C; Ferris S H; Ernesto C; Grundman M; Sano M; Bieliauskas L; Geldmacher D; Clark C; Thal L J
Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S13-21.
1997: Ferris S H; Mackell J A; Mohs R; Schneider L S; Galasko D; Whitehouse P J; Schmitt F A; Sano M; Thomas R G; Ernesto C; Grundman M; Schafer K; Thal L J
A multicenter evaluation of new treatment efficacy instruments for Alzheimer's disease clinical trials: overview and general results. The Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1997;11 Suppl 2():S1-12.
1996: Thal L J; Schwartz G; Sano M; Weiner M; Knopman D; Harrell L; Bodenheimer S; Rossor M; Philpot M; Schor J; Goldberg A
A multicenter double-blind study of controlled-release physostigmine for the treatment of symptoms secondary to Alzheimer's disease. Physostigmine Study Group.
Neurology 1996;47(6):1389-95.
1996: Thal L J; Carta A; Clarke W R; Ferris S H; Friedland R P; Petersen R C; Pettegrew J W; Pfeiffer E; Raskind M A; Sano M; Tuszynski M H; Woolson R F
A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease.
Neurology 1996;47(3):705-11.
1996: Xia Y; Rohan de Silva H A; Rosi B L; Yamaoka L H; Rimmler J B; Pericak-Vance M A; Roses A D; Chen X; Masliah E; DeTeresa R; Iwai A; Sundsmo M; Thomas R G; Hofstetter C R; Gregory E; Hansen L A; Katzman R; Thal L J; Saitoh T
Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism.
Annals of neurology 1996;40(2):207-15.
1996: Salmon D P; Galasko D; Hansen L A; Masliah E; Butters N; Thal L J; Katzman R
Neuropsychological deficits associated with diffuse Lewy body disease.
Brain and cognition 1996;31(2):148-65.
1996: Peskind E R; Raskind M A; Wingerson D; Pascualy M; Thal L J; Dobie D J; Wilkinson C W
Hypothalamic-pituitary-adrenocortical axis responses to physostigmine: effects of Alzheimer's disease and gender.
Biological psychiatry 1996;40(1):61-8.
1996: Olichney J M; Hansen L A; Galasko D; Saitoh T; Hofstetter C R; Katzman R; Thal L J
The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant.
Neurology 1996;47(1):190-6.
1996: Ellis R J; Olichney J M; Thal L J; Mirra S S; Morris J C; Beekly D; Heyman A
Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV.
Neurology 1996;46(6):1592-6.
1996: Grundman M; Corey-Bloom J; Jernigan T; Archibald S; Thal L J
Low body weight in Alzheimer's disease is associated with mesial temporal cortex atrophy.
Neurology 1996;46(6):1585-91.
1996: Peavy G M; Salmon D P; Rice V A; Galasko D; Samuel W; Taylor K I; Ernesto C; Butters N; Thal L
Neuropsychological assessment of severely demeted elderly: the severe cognitive impairment profile.
Archives of neurology 1996;53(4):367-72.
1996: Thal L J
Neurotrophic factors.
Progress in brain research 1996;109():327-30.
1996: Thal L J
Cholinomimetic treatment of Alzheimer's disease.
Progress in brain research 1996;109():299-309.
1996: Thal L J
Potential prevention strategies for Alzheimer disease.
Alzheimer disease and associated disorders 1996;10 Suppl 1():6-8.
1996: Sano M; Ernesto C; Klauber M R; Schafer K; Woodbury P; Thomas R; Grundman M; Growdon J; Thal L J
Rationale and design of a multicenter study of selegiline and alpha-tocopherol in the treatment of Alzheimer disease using novel clinical outcomes. Alzheimer's Disease Cooperative Study.
Alzheimer disease and associated disorders 1996;10(3):132-40.
1996: Ellis R J; Caligiuri M; Galasko D; Thal L J
Extrapyramidal motor signs in clinically diagnosed Alzheimer disease.
Alzheimer disease and associated disorders 1996;10(2):103-14.
1996: Waite J J; Thal L J
Lesions of the cholinergic nuclei in the rat basal forebrain: excitotoxins vs. an immunotoxin.
Life sciences 1996;58(22):1947-53.
1995: Bondi M W; Salmon D P; Monsch A U; Galasko D; Butters N; Klauber M R; Thal L J; Saitoh T
Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults.
Neurology 1995;45(12):2203-6.
1995: Winkler J; Thal L J
Effects of nerve growth factor treatment on rats with lesions of the nucleus basalis magnocellularis produced by ibotenic acid, quisqualic acid, and AMPA.
Experimental neurology 1995;136(2):234-50.
1995: Peskind E R; Wingerson D; Pascualy M; Thal L; Veith R C; Dorsa D M; Bodenheimer S; Raskind M A
Oral physostigmine in Alzheimer's disease: effects on norepinephrine and vasopressin in cerebrospinal fluid and plasma.
Biological psychiatry 1995;38(8):532-8.
1995: Chen X; Xia Y; Alford M; DeTeresa R; Hansen L; Klauber M R; Katzman R; Thal L; Masliah E; Saitoh T
The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease.
Annals of neurology 1995;38(4):653-8.
1995: Monsch A U; Bondi M W; Salmon D P; Butters N; Thal L J; Hansen L A; Wiederholt W C; Cahn D A; Klauber M R
Clinical validity of the Mattis Dementia Rating Scale in detecting Dementia of the Alzheimer type. A double cross-validation and application to a community-dwelling sample.
Archives of neurology 1995;52(9):899-904.
1995: Katzman R; Galasko D; Saitoh T; Thal L J; Hansen L
Genetic evidence that the Lewy body variant is indeed a phenotypic variant of Alzheimer's disease.
Brain and cognition 1995;28(3):259-65.
1995: Olichney J M; Hofstetter C R; Galasko D; Thal L J; Katzman R
Death certificate reporting of dementia and mortality in an Alzheimer's disease research center cohort.
Journal of the American Geriatrics Society 1995;43(8):890-3.
1995: Olichney J M; Hansen L A; Hofstetter C R; Grundman M; Katzman R; Thal L J
Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension.
Archives of neurology 1995;52(7):702-8.
1995: Winkler J; Suhr S T; Gage F H; Thal L J; Fisher L J
Essential role of neocortical acetylcholine in spatial memory.
Nature 1995;375(6531):484-7.
1995: Peskind E R; Raskind M A; Wingerson D; Pascualy M; Thal L J; Dobie D J; Veith R C; Dorsa D M; Murray S; Sikkema C
Enhanced hypothalamic-pituitary-adrenocortical axis responses to physostigmine in normal aging.
The journals of gerontology. Series A, Biological sciences and medical sciences 1995;50(2):M114-20.
1995: Kaplan R M; Anderson J P; Patterson T L; McCutchan J A; Weinrich J D; Heaton R K; Atkinson J H; Thal L; Chandler J; Grant I
Validity of the Quality of Well-Being Scale for persons with human immunodeficiency virus infection. HNRC Group. HIV Neurobehavioral Research Center.
Psychosomatic medicine 1995;57(2):138-47.
1995: Waite J J; Chen A D; Wardlow M L; Wiley R G; Lappi D A; Thal L J
192 immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells.
Neuroscience 1995;65(2):463-76.
1995: Corey-Bloom J; Thal L J; Galasko D; Folstein M; Drachman D; Raskind M; Lanska D J
Diagnosis and evaluation of dementia.
Neurology 1995;45(2):211-8.
1995: Saitoh T; Xia Y; Chen X; Masliah E; Galasko D; Shults C; Thal L J; Hansen L A; Katzman R
The CYP2D6B mutant allele is overrepresented in the Lewy body variant of Alzheimer's disease.
Annals of neurology 1995;37(1):110-2.
1995: Waite J J; Thal L J
The behavioral effects of heptylphysostigmine on rats lesioned in the nucleus basalis.
Neuroscience research 1995;21(3):251-9.
1995: Olichney J M; Galasko D; Corey-Bloom J; Thal L J
The spectrum of diseases with diffuse Lewy bodies.
Advances in neurology 1995;65():159-70.
1994: Waite J J; Chen A D; Wardlow M L; Thal L J
Behavioral and biochemical consequences of combined lesions of the medial septum/diagonal band and nucleus basalis in the rat when ibotenic acid, quisqualic acid, and AMPA are used.
Experimental neurology 1994;130(2):214-29.
1994: Galasko D; Saitoh T; Xia Y; Thal L J; Katzman R; Hill L R; Hansen L
The apolipoprotein E allele epsilon 4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease.
Neurology 1994;44(10):1950-1.
1994: Kawas C; Segal J; Stewart W F; Corrada M; Thal L J
A validation study of the Dementia Questionnaire.
Archives of neurology 1994;51(9):901-6.
1994: Galasko D; Hansen L A; Katzman R; Wiederholt W; Masliah E; Terry R; Hill L R; Lessin P; Thal L J
Clinical-neuropathological correlations in Alzheimer's disease and related dementias.
Archives of neurology 1994;51(9):888-95.
1994: Winkler J; Connor D J; Frautschy S A; Behl C; Waite J J; Cole G M; Thal L J
Lack of long-term effects after beta-amyloid protein injections in rat brain.
Neurobiology of aging 1994;15(5):601-7.
1994: Dekker A J; Winkler J; Ray J; Thal L J; Gage F H
Grafting of nerve growth factor-producing fibroblasts reduces behavioral deficits in rats with lesions of the nucleus basalis magnocellularis.
Neuroscience 1994;60(2):299-309.
1994: Dekker A J; Fagan A M; Gage F H; Thal L J
Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis.
Brain research 1994;639(1):149-55.
1994: Waite J J; Wardlow M L; Chen A C; Lappi D A; Wiley R G; Thal L J
Time course of cholinergic and monoaminergic changes in rat brain after immunolesioning with 192 IgG-saporin.
Neuroscience letters 1994;169(1-2):154-8.
1994: Sewell D D; Jeste D V; Atkinson J H; Heaton R K; Hesselink J R; Wiley C; Thal L; Chandler J L; Grant I
HIV-associated psychosis: a study of 20 cases. San Diego HIV Neurobehavioral Research Center Group.
The American journal of psychiatry 1994;151(2):237-42.
1994: Iragui V J; Kalmijn J; Thal L J; Grant I
Neurological dysfunction in asymptomatic HIV-1 infected men: evidence from evoked potentials. HNRC Group.
Electroencephalography and clinical neurophysiology 1994;92(1):1-10.
1994: Thal L J
Future directions for research in Alzheimer's disease.
Neurobiology of aging 1994;15 Suppl 2():S71-2.
1993: Connor D J; Langdon D J; Langlais P J; Thal L J
Effects of NBm lesions on T-maze performance and thalamic biochemistry.
Neurobiology of aging 1993;14(6):535-7.
1993: Fisher L J; Schinstine M; Salvaterra P; Dekker A J; Thal L; Gage F H
In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase.
Journal of neurochemistry 1993;61(4):1323-32.
1993: Langlais P J; Thal L; Hansen L; Galasko D; Alford M; Masliah E
Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies.
Neurology 1993;43(10):1927-34.
1993: Gulevich S J; McCutchan J A; Thal L J; Kirson D; Durand D; Wallace M; Mehta P; Heyes M P; Grant I
Effect of antiretroviral therapy on the cerebrospinal fluid of patients seropositive for the human immunodeficiency virus.
Journal of acquired immune deficiency syndromes 1993;6(9):1002-7.
1993: Galasko D; Abramson I; Corey-Bloom J; Thal L J
Repeated exposure to the Mini-Mental State Examination and the Information-Memory-Concentration Test results in a practice effect in Alzheimer's disease.
Neurology 1993;43(8):1559-63.
1993: O'Connor D T; Kailasam M T; Thal L J
Cerebrospinal fluid chromogranin A is unchanged in Alzheimer dementia.
Neurobiology of aging 1993;14(3):267-9.
1993: Langlais P J; Connor D J; Thal L
Comparison of the effects of single and combined neurotoxic lesions of the nucleus basalis magnocellularis and dorsal noradrenergic bundle on learning and memory in the rat.
Behavioural brain research 1993;54(1):81-90.
1993: Dekker A J; Thal L J
Independent effects of cholinergic and serotonergic lesions on acetylcholine and serotonin release in the neocortex of the rat.
Neurochemical research 1993;18(3):277-83.
1993: Dekker A J; Thal L J
Nerve growth factor increases cortical choline acetyltransferase-positive fiber staining without affecting cortical cholinergic neurons.
Brain research 1993;601(1-2):329-32.
1993: Corey-Bloom J; Galasko D; Hofstetter C R; Jackson J E; Thal L J
Clinical features distinguishing large cohorts with possible AD, probable AD, and mixed dementia.
Journal of the American Geriatrics Society 1993;41(1):31-7.
1993: Seubert P; Oltersdorf T; Lee M G; Barbour R; Blomquist C; Davis D L; Bryant K; Fritz L C; Galasko D; Thal L J
Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide.
Nature 1993;361(6409):260-3.
1992: Monsch A U; Bondi M W; Butters N; Salmon D P; Katzman R; Thal L J
Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type.
Archives of neurology 1992;49(12):1253-8.
1992: Gulevich S J; Kalmijn J A; Thal L J; Iragui-Madoz V; McCutchan J A; Kennedy C; Grant I
Sensory testing in human immunodeficiency virus type 1-infected men. HIV Neurobehavioral Research Center Group.
Archives of neurology 1992;49(12):1281-4.
1992: Davis K L; Thal L J; Gamzu E R; Davis C S; Woolson R F; Gracon S I; Drachman D A; Schneider L S; Whitehouse P J; Hoover T M
A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group.
The New England journal of medicine 1992;327(18):1253-9.
1992: Connor D J; Thal L J; Mandel R J; Langlais P J; Masliah E
Independent effects of age and nucleus basalis magnocellularis lesion: maze learning, cortical neurochemistry, and morphometry.
Behavioral neuroscience 1992;106(5):776-88.
1992: Waite J; Cole G M; Frautschy S A; Connor D J; Thal L J
Solvent effects on beta protein toxicity in vivo.
Neurobiology of aging 1992;13(5):595-9.
1992: Dekker A J; Thal L J
Effect of delayed treatment with nerve growth factor on choline acetyltransferase activity in the cortex of rats with lesions of the nucleus basalis magnocellularis: dose requirements.
Brain research 1992;584(1-2):55-63.
1992: Connor D J; Dietz S; Langlais P J; Thal L J
Behavioral effects of concurrent lesions of the nucleus basalis magnocellularis and the dorsal noradrenergic bundle.
Experimental neurology 1992;116(1):69-75.
1992: Jeste D V; Wragg R E; Salmon D P; Harris M J; Thal L J
Cognitive deficits of patients with Alzheimer's disease with and without delusions.
The American journal of psychiatry 1992;149(2):184-9.
1992: Thal L J; Gilbertson E; Armstrong D M; Gage F H
Development of the basal forebrain cholinergic system: phenotype expression prior to target innervation.
Neurobiology of aging 1992;13(1):67-72.
1992: Dekker A J; Gage F H; Thal L J
Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: evaluation of the involvement of different neurotransmitter systems.
Neuroscience 1992;48(1):111-9.
1991: Dekker A J; Langdon D J; Gage F H; Thal L J
NGF increases cortical acetylcholine release in rats with lesions of the nucleus basalis.
Neuroreport 1991;2(10):577-80.
1991: Atack J R; Litvan I; Thal L J; May C; Rapoport S I; Chase T N
Cerebrospinal fluid acetylcholinesterase in progressive supranuclear palsy: reduced activity relative to normal subjects and lack of inhibition by oral physostigmine.
Journal of neurology, neurosurgery, and psychiatry 1991;54(9):832-5.
1991: Galasko D; Corey-Bloom J; Thal L J
Monitoring progression in Alzheimer's disease.
Journal of the American Geriatrics Society 1991;39(9):932-41.
1991: Connor D J; Langlais P J; Thal L J
Behavioral impairments after lesions of the nucleus basalis by ibotenic acid and quisqualic acid.
Brain research 1991;555(1):84-90.
1991: Knapp S; Wardlow M L; Albert K; Waters D; Thal L J
Correlation between plasma physostigmine concentrations and percentage of acetylcholinesterase inhibition over time after controlled release of physostigmine in volunteer subjects.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(2):400-4.
1991: Dekker A J; Connor D J; Thal L J
The role of cholinergic projections from the nucleus basalis in memory.
Neuroscience and biobehavioral reviews 1991;15(2):299-317.
1991: Thal L J
Assessment issues in clinical trials of tetrahydroaminoacridine and studies to alter decline in Alzheimer disease.
Alzheimer disease and associated disorders 1991;5 Suppl 1():S37-9.
1990: Salmon D P; Thal L J; Butters N; Heindel W C
Longitudinal evaluation of dementia of the Alzheimer type: a comparison of 3 standardized mental status examinations.
Neurology 1990;40(8):1225-30.
1990: Kwo-On-Yuen P F; Mandel R; Chen A D; Thal L J
Tetrahydroaminoacridine improves the spatial acquisition deficit produced by nucleus basalis lesions in rats.
Experimental neurology 1990;108(3):221-8.
1990: Galasko D; Kwo-on-Yuen P F; Klauber M R; Thal L J
Neurological findings in Alzheimer's disease and normal aging.
Archives of neurology 1990;47(6):625-7.
1990: Thal L J; Mandel R J; Terry R D; Buzsaki G; Gage F H
Nucleus basalis lesions fail to induce senile plaques in the rat.
Experimental neurology 1990;108(1):88-90.
1990: Knapp S; Wardlow M L; Thal L J
Sensitive analysis of plasma physostigmine levels using dual-cell electrochemistry in the redox mode.
Journal of chromatography 1990;526(1):97-107.
1990: Dokla C P; Parker S C; Thal L J
Habituation and retention of the head-shake response: lack of impairment by nucleus basalis magnocellularis lesions.
Pharmacology, biochemistry, and behavior 1990;35(1):151-5.
1990: Galasko D; Klauber M R; Hofstetter C R; Salmon D P; Lasker B; Thal L J
The Mini-Mental State Examination in the early diagnosis of Alzheimer's disease.
Archives of neurology 1990;47(1):49-52.
1990: Hansen L; Salmon D; Galasko D; Masliah E; Katzman R; DeTeresa R; Thal L; Pay M M; Hofstetter R; Klauber M
The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity.
Neurology 1990;40(1):1-8.
1990: Gamzu E R; Thal L J; Davis K L
Therapeutic trials using tacrine and other cholinesterase inhibitors.
Advances in neurology 1990;51():241-5.
1990: Thal L J
THA, a putative drug in the treatment of Alzheimer's disease?
Acta neurologica Scandinavica. Supplementum 1990;129():27-8.
1989: Mandel R J; Chen A D; Connor D J; Thal L J
Continuous physostigmine infusion in rats with excitotoxic lesions of the nucleus basalis magnocellularis: effects on performance in the water maze task and cortical cholinergic markers.
The Journal of pharmacology and experimental therapeutics 1989;251(2):612-9.
1989: Dokla C P; Parker S C; Thal L J
Tetrahydroaminoacridine facilitates passive avoidance learning in rats with nucleus basalis magnocellularis lesions.
Neuropharmacology 1989;28(11):1279-82.
1989: Salmon D P; Kwo-on-Yuen P F; Heindel W C; Butters N; Thal L J
Differentiation of Alzheimer's disease and Huntington's disease with the Dementia Rating Scale.
Archives of neurology 1989;46(11):1204-8.
1989: Masur D M; Fuld P A; Blau A D; Thal L J; Levin H S; Aronson M K
Distinguishing normal and demented elderly with the selective reminding test.
Journal of clinical and experimental neuropsychology 1989;11(5):615-30.
1989: Dokla C P; Thal L J
Nucleus basalis magnocellularis lesions facilitate two-way active avoidance.
Physiology & behavior 1989;46(4):763-5.
1989: Mandel R J; Gage F H; Thal L J
Spatial learning in rats: correlation with cortical choline acetyltransferase and improvement with NGF following NBM damage.
Experimental neurology 1989;104(3):208-17.
1989: Thal L J; Salmon D P; Lasker B; Bower D; Klauber M R
The safety and lack of efficacy of vinpocetine in Alzheimer's disease.
Journal of the American Geriatrics Society 1989;37(6):515-20.
1989: Mandel R J; Gage F H; Thal L J
Enhanced detection of nucleus basalis magnocellularis lesion-induced spatial learning deficit in rats by modification of training regimen.
Behavioural brain research 1989;31(3):221-9.
1989: Thal L J; Lasker B; Sharpless N S; Bobotas G; Schor J M; Nigalye A
Plasma physostigmine concentrations after controlled-release oral administration.
Archives of neurology 1989;46(1):13.
1989: Thal L J; Masur D M; Blau A D; Fuld P A; Klauber M R
Chronic oral physostigmine without lecithin improves memory in Alzheimer's disease.
Journal of the American Geriatrics Society 1989;37(1):42-8.
1988: Dokla C P; Thal L J
Effect of cholinesterase inhibitors on Morris water task behavior following lesions of the nucleus basalis magnocellularis.
Behavioral neuroscience 1988;102(6):861-71.
1988: Thal L J; Dokla C P; Armstrong D M
Nucleus basalis magnocellularis lesions: lack of biochemical and immunocytochemical recovery and effect of cholinesterase inhibitors on passive avoidance.
Behavioral neuroscience 1988;102(6):852-60.
1988: Buzsaki G; Bickford R G; Ponomareff G; Thal L J; Mandel R; Gage F H
Nucleus basalis and thalamic control of neocortical activity in the freely moving rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(11):4007-26.
1988: Katzman R; Brown T; Thal L J; Fuld P A; Aronson M; Butters N; Klauber M R; Wiederholt W; Pay M; Xiong R B
Comparison of rate of annual change of mental status score in four independent studies of patients with Alzheimer's disease.
Annals of neurology 1988;24(3):384-9.
1988: Buzsáki G; Bickford R G; Armstrong D M; Ponomareff G; Chen K S; Ruiz R; Thal L J; Gage F H
Electric activity in the neocortex of freely moving young and aged rats.
Neuroscience 1988;26(3):735-44.
1988: Thal L J; Grundman M; Klauber M R
Dementia: characteristics of a referral population and factors associated with progression.
Neurology 1988;38(7):1083-90.
1988: Thal L J
Dementia update: diagnosis and neuropsychiatric aspects.
The Journal of clinical psychiatry 1988;49 Suppl():5-7.
1988: Galasko D; Kwo-On-Yuen P F; Thal L
Intracranial mass lesions associated with late-onset psychosis and depression.
The Psychiatric clinics of North America 1988;11(1):151-66.
1988: Dickson D W; Horoupian D S; Thal L J; Lantos G
Gliomatosis cerebri presenting with hydrocephalus and dementia.
AJNR. American journal of neuroradiology 1988;9(1):200-2.
1988: Mandel R J; Thal L J
Physostigmine improves water maze performance following nucleus basalis magnocellularis lesions in rats.
Psychopharmacology 1988;96(3):421-5.
1988: Wolfson L I; Sharpless N S; Thal L J
Diminished levels of ventricular fluid norepinephrine metabolite and somatostatin in childhood-onset dystonia.
Advances in neurology 1988;50():177-81.
1987: Thal L J; Davies P
Detection of antigens in Alzheimer cerebrospinal fluid by monoclonal antibodies.
Journal of the American Geriatrics Society 1987;35(12):1047-50.
1987: Wiley C A; VanPatten P D; Carpenter P M; Powell H C; Thal L J
Acute ascending necrotizing myelopathy caused by herpes simplex virus type 2.
Neurology 1987;37(11):1791-4.
1986: Norman A B; Blaker S N; Thal L; Creese I
Effects of aging and cholinergic deafferentation on putative muscarinic cholinergic receptor subtypes in rat cerebral cortex.
Neuroscience letters 1986;70(2):289-94.
1986: Dickson D W; Horoupian D S; Thal L J; Davies P; Walkley S; Terry R D
Klüver-Bucy syndrome and amyotrophic lateral sclerosis: a case report with biochemistry, morphometrics, and Golgi study.
Neurology 1986;36(10):1323-9.
1986: Thal L J; Laing K; Horowitz S G; Makman M H
Dopamine stimulates rat cortical somatostatin release.
Brain research 1986;372(2):205-9.
1986: Thal L J; Grundman M; Golden R
Alzheimer's disease: a correlational analysis of the Blessed Information-Memory-Concentration Test and the Mini-Mental State Exam.
Neurology 1986;36(2):262-4.
1986: Thal L J; Masur D M; Sharpless N S; Fuld P A; Davies P
Acute and chronic effects of oral physostigmine and lecithin in Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 1986;10(3-5):627-36.
1986: Wolfson L I; Thal L J; Brown L L
Serotonin models of myoclonus in the guinea pig and rat.
Advances in neurology 1986;43():519-27.
1986: Katzman R; Brown T; Fuld P; Thal L; Davies P; Terry R
Significance of neurotransmitter abnormalities in Alzheimer's disease.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():279-86.
1985: Thal L J; Sharpless N S; Rosenbaum D; Davies P; Amin I M; Waltz J M
Ventricular fluid somatostatin concentration decreases in childhood-onset dystonia.
Neurology 1985;35(12):1742-6.
1985: Mehta P D; Thal L; Wisniewski H M; Grundke-Iqbal I; Iqbal K
Paired helical filament antigen in CSF.
Lancet 1985;2(8445):35.
1985: Sharpless N S; Thal L J
Plasma physostigmine concentrations after oral administration.
Lancet 1985;1(8442):1397-8.
1985: Thal L J
Changes in cerebrospinal fluid associated with dementia.
Annals of the New York Academy of Sciences 1985;444():235-41.
1984: Horoupian D S; Thal L; Katzman R; Terry R D; Davies P; Hirano A; DeTeresa R; Fuld P A; Petito C; Blass J
Dementia and motor neuron disease: morphometric, biochemical, and Golgi studies.
Annals of neurology 1984;16(3):305-13.
1984: Sharpless N S; Thal L J; Perlow M J; Tabaddor K; Waltz J M; Shapiro K N; Amin I M; Engel J; Crandall P H
Vasoactive intestinal peptide in cerebrospinal fluid.
Peptides 1984;5(2):429-33.
1983: Thal L J; Sharpless N S; Hirschhorn I D; Horowitz S G; Makman M H
Striatal met-enkephalin concentration increases following nigrostriatal denervation.
Biochemical pharmacology 1983;32(22):3297-301.
1983: Thal L J; Sharpless N S
Narcolepsy and hypersomnia.
Neurology 1983;33(10):1394-5.
1983: Schonfeld A R; Thal L J; Horowitz S G; Katzman R
Heart conditioned medium elicits post-lesion muscarinic receptor recovery in vivo.
Brain research 1983;266(2):271-8.
1983: Thal L J; Fuld P A; Masur D M; Sharpless N S
Oral physostigmine and lecithin improve memory in Alzheimer disease.
Annals of neurology 1983;13(5):491-6.
1983: Wolfson L I; Sharpless N S; Thal L J; Waltz J M; Shapiro K
Decreased ventricular fluid norepinephrine metabolite in childhood-onset dystonia.
Neurology 1983;33(3):369-72.
1983: Thal L J; Fuld P A; Masur D M; Sharpless N S; Davies P
Oral physostigmine and lecithin improve memory in Alzheimer's disease.
Psychopharmacology bulletin 1983;19(3):454-6.
1982: Seeger T F; Thal L; Gardner E L
Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: studies with chronic clozapine and haloperidol.
Psychopharmacology 1982;76(2):182-7.
1981: Thal L J; Rosen W; Sharpless N S; Crystal H
Choline chloride in Alzheimer disease.
Annals of neurology 1981;10(6):580.
1981: Schonfeld A R; Thal L J; Horowitz S G; Katzman R
Heart conditioned medium promotes central cholinergic regeneration in vivo.
Brain research 1981;229(2):541-6.
1981: Thal L J; Wolfson L I
Functional anatomy of L-5-hydroxytryptophan-induced myoclonus in the guinea pig.
Neurology 1981;31(8):955-60.
1981: Sharpless N S; Tyce G M; Thal L J; Waltz J M; Tabaddor K; Wolfson L I
Free and conjugated dopamine in human ventricular fluid.
Brain research 1981;217(1):107-18.
1981: Papavasiliou P S; Miller S T; Thal L J; Nerder L J; Houlihan G; Rao S N; Stevens J M
Age-related motor and catecholamine alterations in mice on levodopa supplemented diet.
Life sciences 1981;28(26):2945-52.
1981: Thal L J; Rosen W; Sharpless N S; Crystal H
Choline chloride fails to improve cognition of Alzheimer's disease.
Neurobiology of aging 1981;2(3):205-8.
1980: Makman M H; Dvorkin B; Horowitz S G; Thal L J
Properties of dopamine agonist and antagonist binding sites in mammalian retina.
Brain research 1980;194(2):403-18.
1980: Thal L J; Horowitz S G; Dvorkin B; Makman M H
Evidence for loss of brain [3H]spiroperidil and [3H]ADTN binding sites in rabbit brain with aging.
Brain research 1980;192(1):185-94.
1980: Makman M H; Ahn H S; Thal L J; Sharpless N S; Dvorkin B; Horowitz S G; Rosenfeld M
Evidence for selective loss of brain dopamine- and histamine-stimulated adenylate cyclase activities in rabbits with aging.
Brain research 1980;192(1):177-83.
1980: Thal L J; Sharpless N S; Wolfson L; Katzman R
Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations.
Annals of neurology 1980;7(6):570-6.
1980: Makman M H; Dvorkin B; Horowitz S G; Thal L J
Retina contains guanine nucleotide sensitive and insensitive classes of dopamine receptors.
European journal of pharmacology 1980;63(2-3):217-22.
1980: Rosenfeld M R; Makman M H; Ahn H S; Thal L J; Mishra R K; Katzman R
Selective influence of ergot alkaloids on cortical and striatal dopaminergic and sergotonergic receptors.
Advances in biochemical psychopharmacology 1980;23():83-93.
1979: Thal L; Mishra R K; Gardner E L; Horowitz S G; Varmuza S; Makman M H
Dopamine antagonist binding increases in two behaviorally distinct striatal denervation syndromes.
Brain research 1979;170(2):381-6.
1979: Makman M H; Ahn H S; Thal L J; Sharpless N S; Dvorkin B; Horowitz S G; Rosenfeld M
Aging and monoamine receptors in brain.
Federation proceedings 1979;38(5):1922-6.
1978: Thal L J; Makman M H; Ahn H S; Mishra R K; Horowitz S G; Dvorkin B; Katzman R
3H-Spiroperidol binding and dopamine-stimulated adenylate cyclase: evidence for multiple classes of receptors in primate brain regions.
Life sciences 1978;23(6):629-33.
1978: Thal L; Creese I; Snyder S H
3H-Apomorphine interactions with dopamine receptors in calf brain.
European journal of pharmacology 1978;49(3):295-9.
1978: Makman M H; Ahn H S; Thal L J; Dvorkin B; Horowitz S G; Sharpless N S; Rosenfeld M
Biogenic amine-stimulated adenylate cyclase and spiroperidol-binding sites in rabbit brain: evidence for selective loss of receptors with aging.
Advances in experimental medicine and biology 1978;113():211-30.
1976: Kaufman D M; Thal L J; Farmer P M
Central nervous system aspergillosis in two young adults.
Neurology 1976;26(5):484-8.
1976: Thal L; Sharpless N; Wolfson L; Engel J; Katzman R
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
Transactions of the American Neurological Association 1976;101():48-52.
1971: Datta K; Thal L; Wajda I J
Effects of morphone on choline acetyltransferase levels in the caudate nucleus of the rat.
British journal of pharmacology 1971;41(1):84-93.

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