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Ruediger Thalmann

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TOP 3
Ruediger Thalmann; Isolde Thalmann; Wenfu Lu
Significance of tertiary conformation of otoconial matrix proteins - clinical implications.
Wenfu Lu; Dan Zhou; John J Freeman; Isolde Thalmann; David M Ornitz; Ruediger Thalmann
In vitro effects of recombinant otoconin 90 upon calcite crystal growth. Significance of tertiary structure.
Inna Hughes; Isolde Thalmann; Ruediger Thalmann; David M Ornitz
Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development.

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All Publications

2011: Ruediger Thalmann; Isolde Thalmann; Wenfu Lu
Significance of tertiary conformation of otoconial matrix proteins - clinical implications.
Acta oto-laryngologica 2011;131(4):382-90.
2010: Wenfu Lu; Dan Zhou; John J Freeman; Isolde Thalmann; David M Ornitz; Ruediger Thalmann
In vitro effects of recombinant otoconin 90 upon calcite crystal growth. Significance of tertiary structure.
Hearing research 2010;268(1-2):172-83.
2006: Inna Hughes; Isolde Thalmann; Ruediger Thalmann; David M Ornitz
Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development.
Brain research 2006;1091(1):58-74.
2006: Isolde Thalmann; Inna Hughes; Benton D Tong; David M Ornitz; Ruediger Thalmann
Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti.
Electrophoresis 2006;27(8):1598-608.
2004: Inna Hughes; Brian Blasiole; David Huss; Mark E Warchol; Nigam P Rath; Belen Hurle; Elena G Ignatova; J David Dickman; Ruediger Thalmann; Robert Levenson; David M Ornitz
Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio.
Developmental biology 2004;276(2):391-402.
2004: Elena G Ignatova; Isolde Thalmann; Baogang Xu; David M Ornitz; Ruediger Thalmann
Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice.
Hearing research 2004;194(1-2):65-72.
2004: Michael T Henzl; Isolde Thalmann; John D Larson; Elena G Ignatova; Ruediger Thalmann
The cochlear F-box protein OCP1 associates with OCP2 and connexin 26.
Hearing research 2004;191(1-2):101-9.
2004: D Yang; Isolde Thalmann; Ruediger Thalmann; D D Simmons
Expression of alpha and beta parvalbumin is differentially regulated in the rat organ of corti during development.
Journal of neurobiology 2004;58(4):479-92.
2003: Belen Hurle; Elena G Ignatova; Silvia M Massironi; Tomoji Mashimo; Xavier Rios; Isolde Thalmann; Ruediger Thalmann; David M Ornitz
Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.
Human molecular genetics 2003;12(7):777-89.
2003: Ruediger Thalmann; Michael T Henzl; Richard Killick; Elena G Ignatova; Isolde Thalmann
Toward an understanding of cochlear homeostasis: the impact of location and the role of OCP1 and OCP2.
Acta oto-laryngologica 2003;123(2):203-8.
2002: Keren Kammen-Jolly; Arne W Scholtz; Alfons Kreczy; Rudolf Glückert; Isolde Thalmann; Ruediger Thalmann; Anneliese Schrott-Fischer
OCP2 immunoreactivity in the human fetal cochlea at weeks 11, 17, 20, and 28, and the human adult cochlea.
Hearing research 2002;167(1-2):102-9.
2001: Ruediger Thalmann; Elena G Ignatova; Anne E White-Olson; David M Ornitz; Isolde Thalmann
Development and maintenance of otoconia: biochemical considerations.
Annals of the New York Academy of Sciences 2001;942():162-78.
2001: Michael T Henzl; J O'Neal; R Killick; Isolde Thalmann; Ruediger Thalmann
OCP1, an F-box protein, co-localizes with OCP2/SKP1 in the cochlear epithelial gap junction region.
Hearing research 2001;157(1-2):100-11.
2000: Ulysses Lins; M Farina; Mauricio Kurc; Gavin P Riordan; Ruediger Thalmann; Isolde Thalmann; Anne E White-Olson
The otoconia of the guinea pig utricle: internal structure, surface exposure, and interactions with the filament matrix.
Journal of structural biology 2000;131(1):67-78.
1999: Y Wang; Isolde Thalmann; Ruediger Thalmann; David M Ornitz
Mapping the mouse otoconin-90 (Oc90) gene to chromosome 15.
Genomics 1999;58(2):214-5.
1999: Ruediger Thalmann; Isolde Thalmann
Source and role of endolymph macromolecules.
Acta oto-laryngologica 1999;119(3):293-6.
1998: Y Wang; P E Kowalski; Isolde Thalmann; David M Ornitz; Dixie L Mager; Ruediger Thalmann
Otoconin-90, the mammalian otoconial matrix protein, contains two domains of homology to secretory phospholipase A2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15345-50.
1998: Michael T Henzl; Isolde Thalmann; Ruediger Thalmann
OCP2 exists as a dimer in the organ of Corti.
Hearing research 1998;126(1-2):37-46.
1998: David M Ornitz; Barbara A Bohne; Isolde Thalmann; Gary W Harding; Ruediger Thalmann
Otoconial agenesis in tilted mutant mice.
Hearing research 1998;122(1-2):60-70.
1998: N Sakaguchi; Michael T Henzl; Isolde Thalmann; Ruediger Thalmann; Bradley A Schulte
Oncomodulin is expressed exclusively by outer hair cells in the organ of Corti.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(1):29-40.
1997: Michael T Henzl; O Shibasaki; T H Comegys; Isolde Thalmann; Ruediger Thalmann
Oncomodulin is abundant in the organ of Corti.
Hearing research 1997;106(1-2):105-11.
1997: Ruediger Thalmann; Michael T Henzl; Isolde Thalmann
Specific proteins of the organ of Corti.
Acta oto-laryngologica 1997;117(2):265-8.
1997: E R Yoho; GN Thomopoulos; Isolde Thalmann; Ruediger Thalmann; Bradley A Schulte
Localization of organ of Corti protein II in the adult and developing gerbil cochlea.
Hearing research 1997;104(1-2):47-56.
1995: Isolde Thalmann; O Shibasaki; T H Comegys; Michael T Henzl; M Senarita; Ruediger Thalmann
Detection of a beta-parvalbumin isoform in the mammalian inner ear.
Biochemical and biophysical research communications 1995;215(1):142-7.
1995: M Senarita; Isolde Thalmann; O Shibasaki; Ruediger Thalmann
Calcium-binding proteins in organ of Corti and basilar papilla: CBP-15, an unidentified calcium-binding protein of the inner ear.
Hearing research 1995;90(1-2):169-75.
1995: H Chen; Isolde Thalmann; Joe C Adams; Karen B Avraham; N G Copeland; N A Jenkins; David Beier; David P Corey; Ruediger Thalmann; Geoffrey Duyk
cDNA cloning, tissue distribution, and chromosomal localization of Ocp2, a gene encoding a putative transcription-associated factor predominantly expressed in the auditory organs.
Genomics 1995;27(3):389-98.
1995: Isolde Thalmann; R I Kohut; J H Ryu; Ruediger Thalmann
High resolution two-dimensional electrophoresis: technique and potential applicability to the study of inner ear disease.
The American journal of otology 1995;16(2):153-7.
1994: Isolde Thalmann; R I Kohut; J Ryu; T H Comegys; M Senarita; Ruediger Thalmann
Protein profile of human perilymph: in search of markers for the diagnosis of perilymph fistula and other inner ear disease.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1994;111(3 Pt 1):273-80.
1993: Isolde Thalmann; K Machiki; A Calabro; V C Hascall; Ruediger Thalmann
Uronic acid-containing glycosaminoglycans and keratan sulfate are present in the tectorial membrane of the inner ear: functional implications.
Archives of biochemistry and biophysics 1993;307(2):391-6.
1993: T Kobayashi; M Rokugo; T Takasaka; Ruediger Thalmann
Differential physiologic effects of perfusion of scala tympani versus scala vestibuli in the ischemic cochlea.
Acta oto-laryngologica 1993;113(4):507-11.
1993: K Machiki; Akira Hara; Jun Kusakari; Isolde Thalmann; Ruediger Thalmann
[Biochemical profile of proteoglycans and glucosaminoglycans of the mammalian tectorial membrane].
Nihon Jibiinkoka Gakkai kaiho 1993;96(1):98-106.
1993: Isolde Thalmann; H Suzuki; D W McCourt; T H Comegys; Ruediger Thalmann
Partial amino acid sequences of organ of Corti proteins OCP1 and OCP2: a progress report.
Hearing research 1993;64(2):191-8.
1992: Isolde Thalmann; T H Comegys; S Z Liu; Z Ito; Ruediger Thalmann
Protein profiles of perilymph and endolymph of the guinea pig.
Hearing research 1992;63(1-2):37-42.
1991: Alec N Salt; K Ohyama; Ruediger Thalmann
Radial communication between the perilymphatic scalae of the cochlea. II: Estimation by bolus injection of tracer into the sealed cochlea.
Hearing research 1991;56(1-2):37-43.
1991: Alec N Salt; K Ohyama; Ruediger Thalmann
Radial communication between the perilymphatic scalae of the cochlea. I: Estimation by tracer perfusion.
Hearing research 1991;56(1-2):29-36.
1991: Alec N Salt; N Inamura; Ruediger Thalmann; A R Vora
Evaluation of procedures to reduce fluid flow in the fistulized guinea-pig cochlea.
Acta oto-laryngologica 1991;111(5):899-907.
1990: Isolde Thalmann; K Takahashi; J Varghese; T H Comegys; Ruediger Thalmann
Biochemical features of major organ of Corti proteins (OCP-I and OCP-II) including partial amino acid sequence.
The Laryngoscope 1990;100(1):99-105.
1990: Isolde Thalmann; H Suzuki; D W McCourt; T H Comegys; Ruediger Thalmann
Partial amino acid sequence of organ of Corti protein OCP-II.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 1990;248(1):15-8.
1989: A Hara; Alec N Salt; Ruediger Thalmann
Perilymph composition in scala tympani of the cochlea: influence of cerebrospinal fluid.
Hearing research 1989;42(2-3):265-71.
1989: Alec N Salt; N Inamura; Ruediger Thalmann; A Vora
Calcium gradients in inner ear endolymph.
American journal of otolaryngology 1989;10(6):371-5.
1988: K Ohyama; Alec N Salt; Ruediger Thalmann
Volume flow rate of perilymph in the guinea-pig cochlea.
Hearing research 1988;35(2-3):119-29.
1988: Alec N Salt; Ruediger Thalmann
Interpretation of endolymph flow results: a comment on 'Longitudinal flow of endolymph measured by distribution of tetraethylammonium and choline in scala media'.
Hearing research 1988;33(3):279-84.
1987: Isolde Thalmann; G Thallinger; Ruediger Thalmann
Otosclerosis: a local manifestation of a generalized connective tissue disorder?
American journal of otolaryngology 1987;8(5):308-16.
1987: Alec N Salt; I Melichar; Ruediger Thalmann
Mechanisms of endocochlear potential generation by stria vascularis.
The Laryngoscope 1987;97(8 Pt 1):984-91.
1987: Isolde Thalmann; G Thallinger; E C Crouch; T H Comegys; N Barrett; Ruediger Thalmann
Composition and supramolecular organization of the tectorial membrane.
The Laryngoscope 1987;97(3 Pt 1):357-67.
1987: Ruediger Thalmann; Isolde Thalmann
Role of amino acids in the inner ear with special reference to tectorial membrane.
Advances in oto-rhino-laryngology 1987;37():5-10.
1987: Alec N Salt; Ruediger Thalmann
New concepts regarding the volume flow of endolymph and perilymph.
Advances in oto-rhino-laryngology 1987;37():11-7.
1987: T Kobayashi; I Ise; Daniel C Marcus; Ruediger Thalmann
Effect of iodoacetic acid upon cochlear potentials.
Acta oto-laryngologica. Supplementum 1987;435():46-54.
1986: Alec N Salt; Ruediger Thalmann; Daniel C Marcus; Barbara A Bohne
Direct measurement of longitudinal endolymph flow rate in the guinea pig cochlea.
Hearing research 1986;23(2):141-51.
1986: Isolde Thalmann; G Thallinger; T H Comegys; Ruediger Thalmann
Collagen--the predominant protein of the tectorial membrane.
ORL; journal for oto-rhino-laryngology and its related specialties 1986;48(2):107-15.
1985: Daniel C Marcus; M Rokugo; Ruediger Thalmann
Effects of barium and ion substitutions in artificial blood on endocochlear potential.
Hearing research 1985;17(1):79-86.
1984: Daniel C Marcus; T Kobayashi; M Rokugo; N Y Marcus; Isolde Thalmann; Ruediger Thalmann
Support of cochlear metabolic and ion transport processes solely by perilymphatic perfusion.
Hearing research 1984;15(3):287-92.
1984: T Kobayashi; M Rokugo; Daniel C Marcus; T H Comegys; Ruediger Thalmann
Prolonged maintenance of endocochlear potential by vascular perfusion with media devoid of oxygen carriers.
Archives of oto-rhino-laryngology 1984;239(3):243-7.
1983: Daniel C Marcus; M Rokugo; Xianxi Ge; Ruediger Thalmann
Response of cochlear potentials to presumed alterations of ionic conductance: endolymphatic perfusion of barium, valinomycin and nystatin.
Hearing research 1983;12(1):17-30.
1983: T Kobayashi; I Ise; Ruediger Thalmann
[Effects of iodoacetic acid upon cochlear potentials and the mechanism of CM2 production].
Nihon Jibiinkoka Gakkai kaiho 1983;86(7):749-60.
1982: J Kambayashi; T Kobayashi; N Y Marcus; J E DeMott; Isolde Thalmann; Ruediger Thalmann
Minimal concentrations of metabolic substrates capable of supporting cochlear potentials.
Hearing research 1982;7(1):105-14.
1982: Isolde Thalmann; T Kobayashi; Ruediger Thalmann
Arguments against a mediating role of the adenylate cyclase--cyclic AMP system in the ototoxic action of loop diuretics.
The Laryngoscope 1982;92(5):589-93.
1982: Ruediger Thalmann; T H Comegys; Isolde Thalmann
Amino acid profiles in inner ear fluids and cerebrospinal fluid.
The Laryngoscope 1982;92(3):321-8.
1982: Isolde Thalmann; N Y Marcus; Ruediger Thalmann
Adenine nucleotides of the organ of Corti under metabolic stress.
The Laryngoscope 1982;92(2):199-203.
1982: J Kambayashi; T Kobayashi; J E DeMott; N Y Marcus; Isolde Thalmann; Ruediger Thalmann
Effect of substrate-free vascular perfusion upon cochlear potentials and glycogen of the stria vascularis.
Hearing research 1982;6(2):223-40.
1981: Ruediger Thalmann; T H Comegys; J E DeMott; Isolde Thalmann
Steep gradients of amino acids between cochlear endolymph and perilymph.
The Laryngoscope 1981;91(11):1785-91.
1981: Daniel C Marcus; J E Demott; T Kobayashi; Xianxi Ge; Ruediger Thalmann
Specificity of action of vanadate to the organ of corti.
Hearing research 1981;5(2-3):231-43.
1981: Ruediger Thalmann; Daniel C Marcus; Isolde Thalmann
Physiological chemistry of cochlear duct.
Acta oto-laryngologica 1981;91(5-6):535-40.
1981: Daniel C Marcus; N Y Marcus; Ruediger Thalmann
Changes in cation contents of stria vascularis with ouabain and potassium-free perfusion.
Hearing research 1981;4(2):149-60.
1980: Isolde Thalmann; H L Rosenthal; Blake William Moore; Ruediger Thalmann
Organ of Corti-specific polypeptides: OCP-I and OCP-II.
Archives of oto-rhino-laryngology 1980;226(3):123-8.
1980: Ruediger Thalmann; Daniel C Marcus; Isolde Thalmann
Biochemistry of the inner ear.
Birth defects original article series 1980;16(4):83-105.
1980: Sanford C Bledsoe; Richard P Bobbin; Ruediger Thalmann; Isolde Thalmann
Stimulus-induced release of endogenous amino acids from skins containing the lateral-line organ in Xenopus laevis.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1980;40(1):97-101.