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Christoph Thiele

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Chemicals & Drugs

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Publications

TOP 3
Anke Penno; Gregor Hackenbroich; Christoph Thiele
Phospholipids and lipid droplets.
Ana Stevanovic; Christoph Thiele
Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1.
Ines Lauria; Esmina Mjumjunov-Crncevic; Luis Spitta; Christoph Thiele; Jan van Üüm; David Walrafen; Thorsten Lang
GLTP Mediated Non-Vesicular GM1 Transport between Native Membranes.

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All Publications

2013: Anke Penno; Gregor Hackenbroich; Christoph Thiele
Phospholipids and lipid droplets.
Biochimica et biophysica acta 2013;1831(3):589-94.
2013: Ana Stevanovic; Christoph Thiele
Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1.
Journal of lipid research 2013;54(2):503-13.
2013: Ines Lauria; Esmina Mjumjunov-Crncevic; Luis Spitta; Christoph Thiele; Jan van Üüm; David Walrafen; Thorsten Lang
GLTP Mediated Non-Vesicular GM1 Transport between Native Membranes.
PloS one 2013;8(3):e59871.
2012: Christoph Thiele; Anne Gaebler; Dominik Hoelper; Kalina Kusserow; Daniel Lohmann; Cyrus Papan; Kira Piotrowitz; Mario Schoene; Andrej Shevchenko; Johanna Spandl; Ana Stevanovic; Lars Kuerschner
Tracing fatty acid metabolism by click chemistry.
ACS chemical biology 2012;7(12):2004-11.
2012: Andreas Max Ernst; Christoph Thiele; Felix Wieland; Francesc-Xabier Contreras; Britta Brügger
Mutual recognition of sphingolipid molecular species in membranes.
Biochimica et biophysica acta 2012;1818(11):2616-22.
2012: Margarete Poppelreuther; Berenice Rudolph; Christoph Thiele; Regina Großmann; Melanie Becker; Chen Du; Robert Ehehalt; Joachim Füllekrug
The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake.
Journal of lipid research 2012;53(5):888-900.
2012: F-Xabier Contreras; Arne Elofsson; Andreas M Ernst; Başak Gönen; Per Haberkant; Erik Lindahl; Rainer Pepperkok; Christoph Thiele; Christian Tischer; Gunnar von Heijne; Felix Wieland; Patrik Björkholm; Britta Brügger
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.
Nature 2012;481(7382):525-9.
2012: Lars Kuerschner; Doris Richter; Andrej Shevchenko; Christer S Ejsing; Anne Gaebler; Hans Kristian Hannibal-Bach; Christoph Thiele
Exogenous ether lipids predominantly target mitochondria.
PloS one 2012;7(2):e31342.
2011: Nicola Bauer; Martin Bornhäuser; Ana-Violeta Fonseca; Daniel Freund; Wieland B Huttner; Jana Karbanová; Doreen Strauss; Christoph Thiele; Michaela Wilsch-Bräuninger; Denis Corbeil
Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles--a role of the endocytic-exocytic pathway.
EMBO molecular medicine 2011;3(7):398-409.
2011: Christine Moessinger; Andrej Shevchenko; Johanna Spandl; Lars Kuerschner; Christoph Thiele
Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine.
The Journal of biological chemistry 2011;286(24):21330-9.
2011: Johanna Spandl; Daniel Lohmann; Lars Kuerschner; Christine Moessinger; Christoph Thiele
Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region.
The Journal of biological chemistry 2011;286(7):5599-606.
2009: Johanna Spandl; Daniel J White; Jan Peychl; Christoph Thiele
Live cell multicolor imaging of lipid droplets with a new dye, LD540.
Traffic (Copenhagen, Denmark) 2009;10(11):1579-84.
2009: Kanako Saito; Veronique Dubreuil; Yoko Arai; Michaela Wilsch-Bräuninger; Dominik Schwudke; Gesine Saher; Takaki Miyata; Georg Breier; Christoph Thiele; Andrej Shevchenko; Klaus-Armin Nave; Wieland B Huttner
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(20):8350-5.
2009: Anne-Marie Marzesco; Michaela Wilsch-Bräuninger; Véronique Dubreuil; Peggy Janich; Katja Langenfeld; Christoph Thiele; Wieland B Huttner; Denis Corbeil
Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol.
FEBS letters 2009;583(5):897-902.
2008: Vinciane Grimard; Julia Massier; Doris Richter; Dominik Schwudke; Yannis Kalaidzidis; Eugenio Fava; Albin Hermetter; Christoph Thiele
siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis.
Journal of lipid research 2008;49(11):2427-40.
2008: Christoph Thiele; Johanna Spandl
Cell biology of lipid droplets.
Current opinion in cell biology 2008;20(4):378-85.
2008: Lars Kuerschner; Christine Moessinger; Christoph Thiele
Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets.
Traffic (Copenhagen, Denmark) 2008;9(3):338-52.
2008: Per Haberkant; Oliver Schmitt; F-Xabier Contreras; Christoph Thiele; Kentaro Hanada; Hein Sprong; Constanze Reinhard; Felix T Wieland; Britta Brügger
Protein-sphingolipid interactions within cellular membranes.
Journal of lipid research 2008;49(1):251-62.
2007: Monika Suchanek; Riikka Hynynen; Gerd Wohlfahrt; Markku Lehto; Marie Johansson; Hannu Saarinen; Anna Radzikowska; Christoph Thiele; Vesa M Olkkonen
The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.
The Biochemical journal 2007;405(3):473-80.
2007: Mareike Florek; Nicola Bauer; Peggy Janich; Michaela Wilsch-Braeuninger; Christine A Fargeas; Anne-Marie Marzesco; Gerhard Ehninger; Christoph Thiele; Wieland B Huttner; Denis Corbeil
Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine.
Cell and tissue research 2007;328(1):31-47.
2006: Eva-Maria Krämer-Albers; Katja Gehrig-Burger; Christoph Thiele; Jacqueline Trotter; Klaus-Armin Nave
Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for dysmyelination in spastic paraplegia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(45):11743-52.
2006: Christer S Ejsing; Eva Duchoslav; Julio Sampaio; Kai Simons; Ron Bonner; Christoph Thiele; Kim Ekroos; Andrej Shevchenko
Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning.
Analytical chemistry 2006;78(17):6202-14.
2006: Hein Sprong; Monika Suchanek; Suzanne M van Dijk; Alexandra Van Remoortere; Judith Klumperman; Diana Avram; Joke van der Linden; Jeanette Leusen; Jaap J van Hellemond; Christoph Thiele
Aberrant receptor-mediated endocytosis of Schistosoma mansoni glycoproteins on host lipoproteins.
PLoS medicine 2006;3(8):e253.
2006: Vesa M Olkkonen; Marie Johansson; Monika Suchanek; Daoguang Yan; Riikka Hynynen; Christian Ehnholm; Matti Jauhiainen; Christoph Thiele; Markku Lehto
The OSBP-related proteins (ORPs): global sterol sensors for co-ordination of cellular lipid metabolism, membrane trafficking and signalling processes?
Biochemical Society transactions 2006;34(Pt 3):389-91.
2006: Soazig Le Lay; Eric Hajduch; Margaret R Lindsay; Xavier Le Lièpvre; Christoph Thiele; Pascal Ferré; Robert Parton; Teymuras V Kurzchalia; Kai Simons; Isabelle Dugail
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis.
Traffic (Copenhagen, Denmark) 2006;7(5):549-61.
2005: Daniela Panáková; Hein Sprong; Eric Marois; Christoph Thiele; Suzanne Eaton
Lipoprotein particles are required for Hedgehog and Wingless signalling.
Nature 2005;435(7038):58-65.
2005: Monika Suchanek; Anna Radzikowska; Christoph Thiele
Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells.
Nature methods 2005;2(4):261-7.
2005: Denis Corbeil; Christoph Thiele; Wieland B Huttner
Tyrosine O-sulfation.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2005;Chapter 14():Unit 14.7.
2005: Lars Kuerschner; Christer S Ejsing; Kim Ekroos; Andrej Shevchenko; Kurt I Anderson; Christoph Thiele
Polyene-lipids: a new tool to image lipids.
Nature methods 2005;2(1):39-45.
2004: Vitali Matyash; Eugeni V Entchev; Fanny Mende; Michaela Wilsch-Bräuninger; Christoph Thiele; Arndt W Schmidt; Hans-Joachim Knölker; Samuel Ward; Teymuras V Kurzchalia
Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16.
PLoS biology 2004;2(10):e280.
2003: Robert Ehehalt; Patrick Keller; Christian Haass; Christoph Thiele; Kai Simons
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts.
The Journal of cell biology 2003;160(1):113-23.
2001: Vitali Matyash; C Geier; A Henske; S Mukherjee; D Hirsh; Christoph Thiele; Bridget Grant; Frederick R Maxfield; Teymuras V Kurzchalia
Distribution and transport of cholesterol in Caenorhabditis elegans.
Molecular biology of the cell 2001;12(6):1725-36.
2000: Y Wang; Christoph Thiele; Wieland B Huttner
Cholesterol is required for the formation of regulated and constitutive secretory vesicles from the trans-Golgi network.
Traffic (Copenhagen, Denmark) 2000;1(12):952-62.
2000: Mikael Simons; EM Krämer; Christoph Thiele; W Stoffel; Jacqueline Trotter
Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains.
The Journal of cell biology 2000;151(1):143-54.
2000: M Blázquez; Christoph Thiele; W B Huttner; Kevin Docherty; Kathleen I J Shennan
Involvement of the membrane lipid bilayer in sorting prohormone convertase 2 into the regulated secretory pathway.
The Biochemical journal 2000;349 Pt 3():843-52.
2000: Christoph Thiele; Matthew J Hannah; F Fahrenholz; Wieland B Huttner
Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles.
Nature cell biology 2000;2(1):42-9.
1999: A Schmidt; M Wolde; Christoph Thiele; W Fest; Hartmut Kratzin; Alexandre Podtelejnikov; Walter Witke; Wieland B Huttner; H D Söling
Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.
Nature 1999;401(6749):133-41.
1998: Christoph Thiele; Wieland B Huttner
Protein and lipid sorting from the trans-Golgi network to secretory granules-recent developments.
Seminars in cell & developmental biology 1998;9(5):511-6.
1998: R Beisswanger; Denis Corbeil; C Vannier; Christoph Thiele; U Dohrmann; R Kellner; K Ashman; C Niehrs; Wieland B Huttner
Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11134-9.
1998: Christoph Thiele; Wieland B Huttner
The disulfide-bonded loop of chromogranins, which is essential for sorting to secretory granules, mediates homodimerization.
The Journal of biological chemistry 1998;273(2):1223-31.
1998: J Uhlemann; Christoph Thiele; Richard Freyer; V Schmidt; Stephan Schüler
[Technical perfusion curriculum--an additional curriculum and complementary graduate curriculum in biomedical device technique].
Biomedizinische Technik. Biomedical engineering 1998;43 Suppl():464-5.
1998: Christoph Thiele; R Paulick; H Stein; R Richter
[Quality assurance of Doppler color ultrasound equipment].
Biomedizinische Technik. Biomedical engineering 1998;43 Suppl():216-7.
1997: Christoph Thiele; Hans-Hermann Gerdes; Wieland B Huttner
Protein secretion: puzzling receptors.
Current biology : CB 1997;7(8):R496-500.