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Joachim Thiem

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Janina Möker; Joachim Thiem
Synthesis and hydrolysis studies of novel glyco-functionalized platinum complexes.
Stephan Boettcher; Martin Matwiejuk; Joachim Thiem
Acceptor-influenced and donor-tuned base-promoted glycosylation.
Carsten-Endres Sowa; Joachim Thiem
En route to sugar-alkaloid conjugates.

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All Publications

2012: Janina Möker; Joachim Thiem
Synthesis and hydrolysis studies of novel glyco-functionalized platinum complexes.
Carbohydrate research 2012;348():14-26.
2012: Stephan Boettcher; Martin Matwiejuk; Joachim Thiem
Acceptor-influenced and donor-tuned base-promoted glycosylation.
Beilstein journal of organic chemistry 2012;8():413-20.
2011: Carsten-Endres Sowa; Joachim Thiem
En route to sugar-alkaloid conjugates.
Carbohydrate research 2011;346(12):1546-50.
2011: Martin Matwiejuk; Joachim Thiem
Defining oxyanion reactivities in base-promoted glycosylations.
Chemical communications (Cambridge, England) 2011;47(29):8379-81.
2011: Daniel Waschke; Julian Thimm; Joachim Thiem
Highly efficient synthesis of ketoheptoses.
Organic letters 2011;13(14):3628-31.
2011: Sebastian Meinke; Andreas Schroven; Joachim Thiem
Sialic acid C-glycosides with aromatic residues: investigating enzyme binding and inhibition of Trypanosoma cruzi trans-sialidase.
Organic & biomolecular chemistry 2011;9(12):4487-97.
2010: Sebastian Kopitzki; Knud J Jensen; Joachim Thiem
Synthesis of benzaldehyde-functionalized glycans: a novel approach towards glyco-SAMs as a tool for surface plasmon resonance studies.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(23):7017-29.
2010: Herwig J Berthold; Stephan Franke; Joachim Thiem; Theo Schotten
Ex post glycoconjugation of phthalocyanines.
The Journal of organic chemistry 2010;75(11):3859-62.
2010: Dirk Schmidt; Joachim Thiem
Chemical synthesis using enzymatically generated building units for construction of the human milk pentasaccharides sialyllacto-N-tetraose and sialyllacto-N-neotetraose epimer.
Beilstein journal of organic chemistry 2010;6():18.
2010: Angela M Scheppokat; Agnes Gerber; Andreas Schroven; Sebastian Meinke; Sebastian Kopitzki; Eugen Beketow; Julian Thimm; Joachim Thiem
Enzymatic glycosylation, inhibitor design, and synthesis and formation of glyco-self assembled monolayers for simulation of recognition.
European journal of cell biology 2010;89(1):39-52.
2009: Károly Agoston; Lars Kröger; Gyula Dékány; Joachim Thiem
Solid-phase random glycosylation.
Journal of combinatorial chemistry 2009;11(5):813-9.
2009: Daniel Lazarevic; Harald Streicher; Joachim Thiem
En route to deoxygenated N-acetyllactosamine analogues employing uridyl and galactosyl transferases.
Carbohydrate research 2009;344(12):1449-52.
2009: Károly Agoston; Lars Kröger; Agnes Agoston; Gyula Dékány; Joachim Thiem
Comparative solution and solid-phase glycosylations toward a disaccharide library.
Carbohydrate research 2009;344(12):1428-33.
2008: Sebastian Meinke; Joachim Thiem
Cross metathesis for the synthesis of novel C-sialosides.
Carbohydrate research 2008;343(10-11):1824-9.
2008: Britta Keyser; Markus Glatzel; Franziska Stellmer; Bastian Kortmann; Zoltan Lukacs; Stefan Kölker; Sven W Sauer; Nicole Muschol; Wilhelm Herdering; Joachim Thiem; Stephen I Goodman; David M Koeller; Kurt Ullrich; Thomas Braulke; Chris Mühlhausen
Transport and distribution of 3-hydroxyglutaric acid before and during induced encephalopathic crises in a mouse model of glutaric aciduria type 1.
Biochimica et biophysica acta 2008;1782(6):385-90.
2007: Astrid Blume; Björn Neubacher; Joachim Thiem; Thomas Peters
Donor substrate binding to trans-sialidase of Trypanosoma cruzi as studied by STD NMR.
Carbohydrate research 2007;342(12-13):1904-9.
2007: Stefan Jürs; Joachim Thiem
From lactose towards a novel galactosylated cyclooctenone.
Carbohydrate research 2007;342(9):1238-43.
2007: Franziska Stellmer; Britta Keyser; Birgitta C Burckhardt; Hermann Koepsell; Thomas Streichert; Markus Glatzel; Sabrina Jabs; Joachim Thiem; Wilhelm Herdering; David M Koeller; Stephen I Goodman; Zoltan Lukacs; Kurt Ullrich; Gerhard Burckhardt; Thomas Braulke; Chris Mühlhausen
3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.
Journal of molecular medicine (Berlin, Germany) 2007;85(7):763-70.
2007: Lars Kröger; Joachim Thiem
Synthesis and evaluation of glycosyl donors with novel leaving groups for transglycosylations employing beta-galactosidase from bovine testes.
Carbohydrate research 2007;342(3-4):467-81.
2007: Andreas Schroven; Sebastian Meinke; Patrick Ziegelmüller; Joachim Thiem
Transsialidase from Trypanosoma cruzi for regio- and stereoselective synthesis of N-acyl-modified sialylated oligosaccharides and measurement of transfer rates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(32):9012-21.
2007: Hagen Bretting; Friedrich Buck; Günter Jacobs; Sebastian Meinke; Angela M Scheppokat; Joachim Thiem
Tandem exploitation of Helix pomatia glycosyltransferases: facile syntheses of H-antigen-bearing oligosaccharides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(25):7144-52.
2006: Markus Stark; Joachim Thiem
Highly functionalized glyco-conjugated hexahydroazepindiones from saccharide imides via the Norrish type II reaction.
Carbohydrate research 2006;341(10):1543-56.
2006: Björn Neubacher; Svenja Scheid; Soerge Kelm; Alberto C C Frasch; Bernd Meyer; Joachim Thiem
Synthesis of Neu5Ac oligosaccharides and analogues by transglycosylation and their binding properties as ligands to MAG.
Chembiochem : a European journal of chemical biology 2006;7(6):896-9.
2006: P Greimel; Sabrina Jabs; Stephan Storch; Slim Cherif; Koichi Honke; Thomas Braulke; Joachim Thiem
In vitro sulfation of N-acetyllactosaminide by soluble recombinant human beta-Gal-3'-sulfotransferase.
Carbohydrate research 2006;341(7):918-24.
2006: Daniel Lazarević; Joachim Thiem
Artificial N-functionalized UDP-glucosamine analogues as modified substrates for N-acetylglucosaminyl transferases.
Carbohydrate research 2006;341(5):569-76.
2006: Chris Mühlhausen; Nicola Ott; Fariba Chalajour; Derya Tilki; Folke Freudenberg; Mona Shahhossini; Joachim Thiem; Kurt Ullrich; Thomas Braulke; Süleyman Ergün
Endothelial effects of 3-hydroxyglutaric acid: implications for glutaric aciduria type I.
Pediatric research 2006;59(2):196-202.
2005: Björn Neubacher; Dirk Schmidt; Patrick Ziegelmuller; Joachim Thiem
Preparation of sialylated oligosaccharides employing recombinant trans-sialidase from Trypanosoma cruzi.
Organic & biomolecular chemistry 2005;3(8):1551-6.
2004: Joanne B Hart; Lars Kröger; Andrew Falshaw; Ruth Falshaw; Erzsébet Farkas; Joachim Thiem; Anna L Win
Enzyme-catalysed synthesis of galactosylated 1D- and 1L-chiro-inositol, 1D-pinitol, myo-inositol and selected derivatives using the beta-galactosidase from the thermophile Thermoanaerobacter sp. strain TP6-B1.
Carbohydrate research 2004;339(11):1857-71.
2004: Saskia Weingarten; Joachim Thiem
Formation of LacNAc mimetics employing novel donor substrates for enzymatic beta 1-->4 galactosylation.
Organic & biomolecular chemistry 2004;2(7):961-2.
2004: Lars Kröger; Dirk Henkensmeier; Andreas Schäfer; Joachim Thiem
Novel O-glycosyl amino acid mimetics as building blocks for O-glycopeptides act as inhibitors of galactosidases.
Bioorganic & medicinal chemistry letters 2004;14(1):73-5.
2004: Götz Milkereit; Michael Morr; Joachim Thiem; Volkmar Vill
Thermotropic and lyotropic properties of long chain alkyl glycopyranosides: part III: pH-sensitive headgroups.
Chemistry and physics of lipids 2004;127(1):47-63.
2004: Joachim Thiem
Substrate specificity and synthetic use of glycosyltransferases.
Ernst Schering Research Foundation workshop 2004;(44):75-94.
2003: Rene Suhr; Pascal Pfefferkorn; Saskia Weingarten; Joachim Thiem
Synthesis of rhamnosylated diosgenyl glucosides as mimetics of cytostatic steroidal saponins from Ornithogalum saindersiae and Galtonia candicans.
Organic & biomolecular chemistry 2003;1(24):4373-9.
2003: Angela Michelle Scheppokat; Hagen Bretting; Joachim Thiem
Fast and efficient synthesis of a novel homologous series of L-fucosylated trisaccharides using the Helix pomatia alpha-(1-->2)-L-galactosyltransferase.
Carbohydrate research 2003;338(20):2083-90.
2002: Synke Rutschow; Joachim Thiem; Christian Kranz; Thorsten Marquardt
Membrane-permeant derivatives of mannose-1-phosphate.
Bioorganic & medicinal chemistry 2002;10(12):4043-9.
2002: Daniel Lazarevic; Joachim Thiem
Syntheses of unnatural N-substituted UDP-galactosamines as alternative substrates for N-acetylgalactosaminyl transferases.
Carbohydrate research 2002;337(21-23):2187-94.
2002: Martina Lahmann; Helena Gybäck; Per J Garegg; Stefan Oscarson; René Suhr; Joachim Thiem
A facile approach to diosgenin and furostan type saponins bearing a 3beta-chacotriose moiety.
Carbohydrate research 2002;337(21-23):2153-9.
2001: S Thiering; C Sund; Joachim Thiem; Anja Giesler; Jürgen Kopf
Syntheses of imido-substituted glycosans and their photocyclisation towards highly functionalised heterotricycles.
Carbohydrate research 2001;336(4):271-82.
2000: D Schmidt; B Sauerbrei; Joachim Thiem
Chemoenzymatic synthesis of sialyl oligosaccharides with sialidases employing transglycosylation methodology.
The Journal of organic chemistry 2000;65(25):8518-26.
2000: Hagen Bretting; M Messer; L Bornaghi; Lars Kröger; P Mischnick; Joachim Thiem
Galactan biosynthesis in snails: a comparative study of beta-(1--> 6) galactosyltransferases from Helix pomatia and Biomphalaria glabrata.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 2000;170(8):601-13.
2000: E Farkas; Joachim Thiem; K Ajisaka
Enzymatic synthesis of fucose-containing disaccharides employing the partially purified alpha-L-fucosidase from Penicillium multicolor.
Carbohydrate research 2000;328(3):293-9.
2000: A Schäfer; Joachim Thiem
Synthesis of novel donor mimetics of UDP-Gal, UDP-GlcNAc, and UDP-GalNAc as potential transferase inhibitors.
The Journal of organic chemistry 2000;65(1):24-9.
1999: R Gonzalez Lio; Joachim Thiem
Chemoenzymatic synthesis of spacer-linked oligosaccharides for the preparation of neoglycoproteins.
Carbohydrate research 1999;317(1-4):180-90.
1998: A Schäfer; G Klich; M Schreiber; Hans Paulsen; Joachim Thiem
Synthesis of an N-glucoasparagine analog as a building block for a V3-loop glycopeptide from gp120 of HIV-I.
Carbohydrate research 1998;313(2):107-16.
1998: Manfred Nimtz; Eckart Grabenhorst; U Gambert; J Costa; V Wray; Michael Morr; Joachim Thiem; Harald S Conradt
In vitro alpha1-3 or alpha1-4 fucosylation of type I and II oligosaccharides with secreted forms of recombinant human fucosyltransferases III and VI.
Glycoconjugate journal 1998;15(9):873-83.
1998: N Taubken; Joachim Thiem
Hydrolase-catalyzed beta-mannosylations.
Glycoconjugate journal 1998;15(8):757-67.
1998: E Wieczorek; Joachim Thiem
Preparation of modified glycosyl glycerol derivatives by glycal rearrangement.
Carbohydrate research 1998;307(3-4):263-70.
1997: Vladimír Kren; J Dvoráková; U Gambert; Petr Sedmera; Vladimír Havlícek; Joachim Thiem; Karel Bezouska
beta-Glucosylation of chitooligomers by galactosyltransferase.
Carbohydrate research 1997;305(3-4):517-23.
1997: K Stangier; Monica Palcic; David R Bundle; Ole Hindsgaul; Joachim Thiem
Fucosyltransferase-catalyzed formation of L-galactosylated Lewis structures.
Carbohydrate research 1997;305(3-4):511-5.
1997: Karel Bezouska; Jan Sklenár; J Dvoráková; Vladimír Havlícek; Miloslav Pospísil; Joachim Thiem; Vladimír Kren
NKR-P1A protein, an activating receptor of rat natural killer cells, binds to the chitobiose core of uncompletely glycosylated N-linked glycans, and to linear chitooligomers.
Biochemical and biophysical research communications 1997;238(1):149-53.
1997: U Gambert; R Gonzalez Lio; E Farkas; Joachim Thiem; V Verez Bencomo; András Lipták
Galactosylation with beta-galactosidase from bovine testes employing modified acceptor substrates.
Bioorganic & medicinal chemistry 1997;5(7):1285-91.
1997: B Evers; M Petríćek; Joachim Thiem
Specificity of amylases and cyclodextrin-glucanotransferase in reactions with 2-deoxy-maltooligosaccharides.
Carbohydrate research 1997;300(2):153-9.
1997: B Evers; Joachim Thiem
Further syntheses employing phosphorylase.
Bioorganic & medicinal chemistry 1997;5(5):857-63.
1997: U Gambert; Joachim Thiem
Chemoenzymatic synthesis of the Thomsen-Friedenreich antigen determinant.
Carbohydrate research 1997;299(1-2):85-9.
1997: Martina Lahmann; Joachim Thiem
Synthesis of alpha-tocopheryl oligosaccharides.
Carbohydrate research 1997;299(1-2):23-31.
1997: H Lüttge; T Heidelberg; K Stangier; Joachim Thiem; Hagen Bretting
The specificity of an alpha-(1-->2)-L-galactosyltransferase from albumen glands of the snail Helix pomatia.
Carbohydrate research 1997;297(3):281-8.
1995: G Limberg; W Klaffke; Joachim Thiem
Conversion of aldonic acids to their corresponding 2-keto-3-deoxy-analogs by the non-carbohydrate enzyme dihydroxy acid dehydratase (DHAD).
Bioorganic & medicinal chemistry 1995;3(5):487-94.
1995: Joachim Thiem
Applications of enzymes in synthetic carbohydrate chemistry.
FEMS microbiology reviews 1995;16(2-3):193-211.
1995: K Stangier; H Lüttge; Joachim Thiem; Hagen Bretting
Biosynthesis of the storage polysaccharide from the snail Biomphalaria glabrata, identification and specificity of a branching beta 1-->6 galactosyltransferase.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 1995;165(4):278-90.
1994: P Mischnick; B Evers; Joachim Thiem
Analysis of oligosaccharides containing 2-deoxy-alpha-D-arabino-hexosyl residues by the reductive-cleavage method.
Carbohydrate research 1994;264(2):293-304.
1994: L Laupichler; C E Sowa; Joachim Thiem
Synthesis and structural studies of asparagine-modified 2-deoxy-alpha-N-glycopeptides associated with the renin-angiotensin system.
Bioorganic & medicinal chemistry 1994;2(11):1281-94.
1994: Y Nishida; Joachim Thiem
Convenient synthetic approach towards C-3 modified methyl beta-lactosides.
Carbohydrate research 1994;263(2):295-301.
1994: B Evers; P Mischnick; Joachim Thiem
Synthesis of 2-deoxy-alpha-D-arabino-hexopyranosyl phosphate and 2-deoxy-maltooligosaccharides with phosphorylase.
Carbohydrate research 1994;262(2):335-41.
1994: S Köpper; Joachim Thiem
One-pot-synthesis of alpha-linked deoxy sugar trisaccharides.
Carbohydrate research 1994;260(2):219-32.
1994: T Wiemann; N Taubken; U Zehavi; Joachim Thiem
Enzymic synthesis of N-acetyllactosamine on a soluble, light-sensitive polymer.
Carbohydrate research 1994;257(1):C1-6.
1993: J Niggemann; Thisbe K Lindhorst; M Walfort; L Laupichler; H Sajus; Joachim Thiem
Synthetic approaches to 2-deoxyglycosyl phosphates.
Carbohydrate research 1993;246():173-83.
1993: T Schmelter; S Ivanov; M Wember; P Stangier; Joachim Thiem; Roland Schauer
Partial purification and characterization of cytidine-5'-monophosphosialate synthase from rainbow trout liver.
Biological chemistry Hoppe-Seyler 1993;374(5):337-42.
1993: P Stangier; W Treder; Joachim Thiem
Chemoenzymatic galactosialylation with integrated cofactor regeneration.
Glycoconjugate journal 1993;10(1):26-33.
1992: T Böcker; Thisbe K Lindhorst; Joachim Thiem; V Vill
Synthesis and properties of sulfated alkyl glycosides.
Carbohydrate research 1992;230(2):245-56.
1992: Joachim Thiem; P Stangier; P Matschulat; Hans Paulsen
Synthesis of a glycosidic affinity ligand for purification of cytidine-5'-monophosphosialate synthase.
Carbohydrate research 1992;225(1):147-50.
1991: W Klaffke; D Springer; Joachim Thiem
Approaches to the C-B-A trisaccharide of dihydroaclacinomycin by extending the chain from either side.
Carbohydrate research 1991;216():475-81.