Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Christoph Thiemermann

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Disorders

Anatomy

Kidney

Physiology

Hemodynamics

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
86
Cuzzocrea, Salvatore
56
Vane, JR
46
Mazzon, Emanuela
44
Chatterjee, Prabal
40
Patel, Nimesh
39
McDonald, Michelle
35
Caputi, Achille
29
Dugo, Laura
29
Mota-Filipe, Helder
26
Di Paola, Rosanna
21
Britti, Domenico
20
Genovese, Tiziana
19
Aasen, Ansgar
19
Szabó, Csaba
17
Wang, Jacob

Sign-in to see all Coauthors

Publications

TOP 3
Eltze Tobias; Boer Rainer; Wagner Thomas; Weinbrenner Steffen; McDonald Michelle C; Thiemermann Christoph; Bürkle Alexander; Klein Thomas
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
Tripatara Pinpat; Patel Nimesh S A; Collino Massimo; Gallicchio Margherita; Kieswich Julius; Castiglia Sara; Benetti Elisa; Stewart Keith N; Brown Paul A J; Yaqoob Mohammed M; Fantozzi Roberto; Thiemermann Christoph
Generation of endogenous hydrogen sulfide by cystathionine gamma-lyase limits renal ischemia/reperfusion injury and dysfunction.
Thiemermann Christoph
What's new in Shock, September 2008?

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Christoph Thiemermann (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2008: Eltze Tobias; Boer Rainer; Wagner Thomas; Weinbrenner Steffen; McDonald Michelle C; Thiemermann Christoph; Bürkle Alexander; Klein Thomas
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
Molecular pharmacology 2008;74(6):1587-98.
2008: Tripatara Pinpat; Patel Nimesh S A; Collino Massimo; Gallicchio Margherita; Kieswich Julius; Castiglia Sara; Benetti Elisa; Stewart Keith N; Brown Paul A J; Yaqoob Mohammed M; Fantozzi Roberto; Thiemermann Christoph
Generation of endogenous hydrogen sulfide by cystathionine gamma-lyase limits renal ischemia/reperfusion injury and dysfunction.
Laboratory investigation; a journal of technical methods and pathology 2008;88(10):1038-48.
2008: Thiemermann Christoph
What's new in Shock, September 2008?
Shock (Augusta, Ga.) 2008;30(3):227-30.
2008: Collino Massimo; Thiemermann Christoph; Mastrocola Raffaella; Gallicchio Margherita; Benetti Elisa; Miglio Gianluca; Castiglia Sara; Danni Oliviero; Murch Oliver; Dianzani Chiara; Aragno Manuela; Fantozzi Roberto
Treatment with the glycogen synthase kinase-3beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus.
Shock (Augusta, Ga.) 2008;30(3):299-307.
2008: Todorovic Zoran; Nesic Zorica; Stojanovic Radan; Basta-Jovanovic Gordana; Radojevic-Skodric Sanja; Velickovic Ruzca; Chatterjee Prabal K; Thiemermann Christoph; Prostran Milica
Acute protective effects of simvastatin in the rat model of renal ischemia-reperfusion injury: it is never too late for the pretreatment.
Journal of pharmacological sciences 2008;107(4):465-70.
2008: Brines Michael; Patel Nimesh S A; Villa Pia; Brines Courtenay; Mennini Tiziana; De Paola Massimiliano; Erbayraktar Zubeyde; Erbayraktar Serhat; Sepodes Bruno; Thiemermann Christoph; Ghezzi Pietro; Yamin Michael; Hand Carla C; Xie Qiao-wen; Coleman Thomas; Cerami Anthony
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10925-30.
2008: Thiemermann Christoph
What's new in Shock, April 2008?
Shock (Augusta, Ga.) 2008;29(4):427-30.
2008: Myhre Anders E; Agren Joanna; Dahle Maria K; Tamburstuen Margareth V; Lyngstadaas Ståle P; Collins A Jon L; Foster Simon J; Thiemermann Christoph; Aasen Ansgar O; Wang Jacob E
Liver X receptor is a key regulator of cytokine release in human monocytes.
Shock (Augusta, Ga.) 2008;29(4):468-74.
2008: Thiemermann Christoph
What's new in shock, March 2008.
Shock (Augusta, Ga.) 2008;29(3):311-4.
2008: Murch Oliver; Abdelrahman Maha; Kapoor Amar; Thiemermann Christoph
Muramyl dipeptide enhances the response to endotoxin to cause multiple organ injury in the anesthetized rat.
Shock (Augusta, Ga.) 2008;29(3):388-94.
2008: Murch Oliver; Abdelrahman Maha; Collino Massimo; Gallicchio Margherita; Benetti Elisa; Mazzon Emanuela; Fantozzi Roberto; Cuzzocrea Salvatore; Thiemermann Christoph
Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.
Critical care medicine 2008;36(2):550-9.
2007: Cuzzocrea Salvatore; Malleo Giuseppe; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Abdelrahman Maha; Di Paola Rosanna; Thiemermann Cristoph
Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice.
Critical care medicine 2007;35(12):2811-21.
2007: Ruud Tom E; Gundersen Yngvar; Wang Jacob E; Foster Simon J; Thiemermann Christoph; Aasen Ansgar O
Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro.
Surgical infections 2007;8(5):495-503.
2007: Bao Zhang; Lim Shuhui; Liao Wupeng; Lin Yuzhi; Thiemermann Christoph; Leung Bernard P; Wong W S Fred
Glycogen synthase kinase-3beta inhibition attenuates asthma in mice.
American journal of respiratory and critical care medicine 2007;176(5):431-8.
2007: Cuzzocrea S; Genovese T; Mazzon E; Esposito E; Muià C; Abdelrahman M; Di Paola R; Bramanti P; Thiemermann C
Glycogen synthase kinase-3beta inhibition attenuates the development of bleomycin-induced lung injury.
International journal of immunopathology and pharmacology 2007;20(3):619-30.
2007: Albuszies Gerd; Vogt Josef; Wachter Ulrich; Thiemermann Christoph; Leverve Xavier M; Weber Sandra; Georgieff Michael; Radermacher Peter; Barth Eberhard
The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock.
Intensive care medicine 2007;33(6):1094-101.
2007: Hadley Julia S; Wang Jacob E; Michaels Louis C; Dempsey Charlotte M; Foster Simon J; Thiemermann Christoph; Hinds Charles J
Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils after cardiopulmonary bypass.
Shock (Augusta, Ga.) 2007;27(5):466-73.
2007: Thiemermann Christoph
What's new in shock, May 2007?
Shock (Augusta, Ga.) 2007;27(5):457-60.
2007: Cuzzocrea Salvatore; Mazzon Emanuela; Esposito Emanuela; Muià Carmelo; Abdelrahman Maha; Di Paola Rosanna; Crisafulli Concetta; Bramanti Placido; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut.
Intensive care medicine 2007;33(5):880-93.
2007: Patel Nimesh S A; Cuzzocrea Salvatore; Collino Massimo; Chaterjee Prabal K; Mazzon Emanuela; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo.
European journal of pharmacology 2007;562(1-2):148-54.
2007: Cartwright Neil; Murch Oliver; McMaster Shaun K; Paul-Clark Mark J; van Heel David A; Ryffel Bernhard; Quesniaux Valerie F J; Evans Timothy W; Thiemermann Christoph; Mitchell Jane A
Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.
American journal of respiratory and critical care medicine 2007;175(6):595-603.
2007: Dugo Laura; Collin Marika; Thiemermann Christoph
Glycogen synthase kinase 3beta as a target for the therapy of shock and inflammation.
Shock (Augusta, Ga.) 2007;27(2):113-23.
2007: Tripatara Pinpat; Patel Nimesh S A; Webb Andrew; Rathod Krishnaraj; Lecomte Florence M J; Mazzon Emanuela; Cuzzocrea Salvatore; Yaqoob Mohammed M; Ahluwalia Amrita; Thiemermann Christoph
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase.
Journal of the American Society of Nephrology : JASN 2007;18(2):570-80.
2007: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Crisafulli Concetta; Genovese Tiziana; Muià Carmelo; Abdelrahman Maha; Esposito Emanuela; Thiemermann Christoph
Glycogen synthase kinase 3beta inhibition reduces the development of nonseptic shock induced by zymosan in mice.
Shock (Augusta, Ga.) 2007;27(1):97-107.
2007: Murch Oliver; Collin Marika; Thiemermann Christoph
Lysophosphatidic acid reduces the organ injury caused by endotoxemia-a role for G-protein-coupled receptors and peroxisome proliferator-activated receptor-gamma.
Shock (Augusta, Ga.) 2007;27(1):48-54.
2007: Murch Oliver; Collin Marika; Hinds Charles J; Thiemermann Christoph
Lipoproteins in inflammation and sepsis. I. Basic science.
Intensive care medicine 2007;33(1):13-24.
2007: Thiemermann Christoph
Beneficial effects of erythropoietin in preclinical models of shock and organ failure.
Critical care (London, England) 2007;11(3):132.
2007: Dugo Laura; Collin Marika; Allen David A; Patel Nimesh S A; Bauer Inge; Mervaala Eero; Louhelainen Marjut; Foster Simon J; Yaqoob Muhammad M; Thiemermann Christoph
Inhibiting glycogen synthase kinase 3beta in sepsis.
Novartis Foundation symposium 2007;280():128-42; discussion 142-6, 160-4.
2006: Nesic Zorica; Todorovic Zoran; Stojanovic Radan; Basta-Jovanovic Gordana; Radojevic-Skodric Sanja; Velickovic Ruzica; Chatterjee Prabal K; Thiemermann Christoph; Prostran Milica
Single-dose intravenous simvastatin treatment attenuates renal injury in an experimental model of ischemia-reperfusion in the rat.
Journal of pharmacological sciences 2006;102(4):413-7.
2006: Sepodes Bruno; Maio Rui; Pinto Rui; Sharples Edward; Oliveira Pedro; McDonald Michelle; Yaqoob Muhammad; Thiemermann Christoph; Mota-Filipe Helder
Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 2006;19(11):919-26.
2006: Cuzzocrea S; Crisafulli C; Mazzon E; Esposito E; Muià C; Abdelrahman M; Di Paola R; Thiemermann C
Inhibition of glycogen synthase kinase-3beta attenuates the development of carrageenan-induced lung injury in mice.
British journal of pharmacology 2006;149(6):687-702.
2006: McCormick James; Barry Sean P; Sivarajah Ahila; Stefanutti Giorgio; Townsend Paul A; Lawrence Kevin M; Eaton Simon; Knight Richard A; Thiemermann Christoph; Latchman David S; Stephanou Anastasis
Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(12):2115-7.
2006: Sivarajah A; McDonald M C; Thiemermann C
The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Shock (Augusta, Ga.) 2006;26(2):154-61.
2006: Collino Massimo; Aragno Manuela; Mastrocola Raffaella; Benetti Elisa; Gallicchio Margherita; Dianzani Chiara; Danni Oliviero; Thiemermann Christoph; Fantozzi Roberto
Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.
Free radical biology & medicine 2006;41(4):579-89.
2006: Thiemermann Christoph
The spice of life: curcumin reduces the mortality associated with experimental sepsis.
Critical care medicine 2006;34(7):2009-11.
2006: Agren J; Thiemermann C; Foster S J; Wang J E; Aasen A O
Cytokine responses to CpG DNA in human leukocytes.
Scandinavian journal of immunology 2006;64(1):61-8.
2006: Murch Oliver; Collin Marika; Sepodes Bruno; Foster Simon J; Mota-Filipe Helder; Thiemermann Christoph
Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shock.
British journal of pharmacology 2006;148(6):769-77.
2006: Bar-Or David; McDonald Michelle C; Thiemermann Christoph
Reduction of infarct size in a rat model of regional myocardial ischemia and reperfusion by the synthetic peptide DAHK.
Critical care medicine 2006;34(7):1955-9.
2006: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Dugo Laura; Collin Marika; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse.
Clinical immunology (Orlando, Fla.) 2006;120(1):57-67.
2006: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Crisafulli Concetta; Di Paola Rosanna; Muià Carmelo; Collin Marika; Esposito Emanuela; Bramanti Placido; Thiemermann Christoph
Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma.
The Journal of pharmacology and experimental therapeutics 2006;318(1):79-89.
2006: Myhre A E; Lyngstadaas S P; Dahle M K; Stuestøl J F; Foster S J; Thiemermann C; Lilleaasen P; Wang J E; Aasen A O
Anti-inflammatory properties of enamel matrix derivative in human blood.
Journal of periodontal research 2006;41(3):208-13.
2006: Dugo Laura; Abdelrahman Maha; Murch Oliver; Mazzon Emanuela; Cuzzocrea Salvatore; Thiemermann Christoph
Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation.
Shock (Augusta, Ga.) 2006;25(5):485-91.
2006: Dugo Laura; Collin Marika; Allen David A; Murch Oliver; Foster Simon J; Yaqoob Muhammad M; Thiemermann Christoph
Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition.
Critical care medicine 2006;34(5):1489-96.
2006: Cuzzocrea Salvatore; Di Paola Rosanna; Mazzon Emanuela; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; Crisafulli Concetta; Caputi Achille P; Thiemermann Christoph
Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice.
Critical care medicine 2006;34(4):1168-77.
2006: Collin Marika; Murch Oliver; Thiemermann Christoph
Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia.
Critical care medicine 2006;34(4):1131-8.
2006: Sharples Edward J; Thiemermann Christoph; Yaqoob Magdi M
Novel applications of recombinant erythropoietin.
Current opinion in pharmacology 2006;6(2):184-9.
2006: Myhre Anders E; Aasen Ansgar O; Thiemermann Christoph; Wang Jacob E
Peptidoglycan--an endotoxin in its own right?
Shock (Augusta, Ga.) 2006;25(3):227-35.
2006: Whittle Brendan J R; Varga Csaba; Pósa Anikó; Molnár Andor; Collin Marika; Thiemermann Christoph
Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta.
British journal of pharmacology 2006;147(5):575-82.
2006: Wang Yun Yong; Dahle Maria K; Agren Joanna; Myhre Anders E; Reinholt Finn P; Foster Simon J; Collins Jon L; Thiemermann Christoph; Aasen Ansgar O; Wang Jacob E
Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation.
Shock (Augusta, Ga.) 2006;25(2):141-6.
2006: Barth Eberhard; Radermacher Peter; Thiemermann Christoph; Weber Sandra; Georgieff Michael; Albuszies Gerd
Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock.
Critical care medicine 2006;34(2):307-13.
2006: Collino Massimo; Aragno Manuela; Mastrocola Raffaella; Gallicchio Margherita; Rosa Arianna Carolina; Dianzani Chiara; Danni Oliviero; Thiemermann Christopher; Fantozzi Roberto
Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion.
European journal of pharmacology 2006;530(1-2):70-80.
2005: Sharples Edward J; Thiemermann Christoph; Yaqoob Magdi M
Mechanisms of disease: Cell death in acute renal failure and emerging evidence for a protective role of erythropoietin.
Nature clinical practice. Nephrology 2005;1(2):87-97.
2005: Collin Marika; Thiemermann Christoph
Hydrogen sulfide and sulfite: novel mediators in the pathophysiology of shock and inflammation.
Shock (Augusta, Ga.) 2005;24(6):595-6.
2005: Hadley J S; Wang J E; Foster S J; Thiemermann C; Hinds C J
Peptidoglycan of Staphylococcus aureus upregulates monocyte expression of CD14, Toll-like receptor 2 (TLR2), and TLR4 in human blood: possible implications for priming of lipopolysaccharide signaling.
Infection and immunity 2005;73(11):7613-9.
2005: Collin Marika; Anuar Farhana B M; Murch Oliver; Bhatia Madhav; Moore Philip K; Thiemermann Christoph
Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.
British journal of pharmacology 2005;146(4):498-505.
2005: Dugo Laura; Collin Marika; Allen David A; Patel Nimesh S A; Bauer Inge; Mervaala Eero M A; Louhelainen Marjut; Foster Simon J; Yaqoob Muhammad M; Thiemermann Christoph
GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat.
Critical care medicine 2005;33(9):1903-12.
2005: Wang Yun Yong; Myhre Anders E; Pettersen Solveig J; Dahle Maria K; Foster Simon J; Thiemermann Christoph; Bjørnland Kristin; Aasen Ansgar O; Wang Jacob E
Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils.
Shock (Augusta, Ga.) 2005;24(3):214-8.
2005: Collino Massimo; Patel Nimesh S A; Lawrence Kevin M; Collin Marika; Latchman David S; Yaqoob Muhammad M; Thiemermann Christoph
The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion.
Kidney international 2005;68(2):529-36.
2005: Sivarajah Ahila; McDonald Michelle C; Thiemermann Christoph
The cardioprotective effects of preconditioning with endotoxin, but not ischemia, are abolished by a peroxisome proliferator-activated receptor-gamma antagonist.
The Journal of pharmacology and experimental therapeutics 2005;313(2):896-901.
2005: Genovese Tiziana; Mazzon Emanuela; Di Paola Rosanna; Muià Carmelo; Threadgill Michael D; Caputi Achille P; Thiemermann Christoph; Cuzzocrea Salvatore
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
The Journal of pharmacology and experimental therapeutics 2005;313(2):529-38.
2005: Chatterjee Prabal K; Todorovic Zoran; Sivarajah Ahila; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Mazzon Emanuela; Cuzzocrea Salvatore; Thiemermann Christoph
Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury.
Biochemical pharmacology 2005;69(7):1121-31.
2005: Cuzzocrea Salvatore; Mazzon Emanuela; di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Britti Domenico; de Majo Massimo; Caputi Achille P; Thiemermann Christoph
Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse.
Arthritis and rheumatism 2005;52(3):940-50.
2005: Abdelrahman Maha; Sivarajah Ahila; Thiemermann Christoph
Beneficial effects of PPAR-gamma ligands in ischemia-reperfusion injury, inflammation and shock.
Cardiovascular research 2005;65(4):772-81.
2005: Patel Nimesh S A; Cortes Ulrich; Di Poala Rosanna; Mazzon Emanuela; Mota-Filipe Helder; Cuzzocrea Salvatore; Wang Zhao-Qi; Thiemermann Christoph
Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury.
Journal of the American Society of Nephrology : JASN 2005;16(3):712-9.
2005: Patel Nimesh S A; Chatterjee Prabal K; Di Paola Rosanna; Mazzon Emanuela; Britti Domenico; De Sarro Angelina; Cuzzocrea Salvatore; Thiemermann Christoph
Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1170-8.
2005: Genovese T; Cuzzocrea S; Di Paola R; Mazzon E; Mastruzzo C; Catalano P; Sortino M; Crimi N; Caputi A P; Thiemermann C; Vancheri C
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(2):225-34.
2005: Abdelrahman Maha; Mazzon Emanuela; Bauer Michael; Bauer Inge; Delbosc Sandrine; Cristol Jean-Paul; Patel Nimesh S A; Cuzzocrea Salvatore; Thiemermann Christoph
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 2005;23(2):107-14.
2005: Genovese Tiziana; Mazzon Emanuela; Muià Carmelo; Patel Nimesh S A; Threadgill Michael D; Bramanti Placido; De Sarro Angelina; Thiemermann Christoph; Cuzzocrea Salvatore
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
The Journal of pharmacology and experimental therapeutics 2005;312(2):449-57.
2005: Di Paola Rosanna; Mazzon Emanuela; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; Thiemermann Christoph; De Sarro Angelina; Cuzzocrea Salvatore
Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid.
European journal of pharmacology 2005;507(1-3):281-9.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Muià Carmelo; Threadgill Michael D; De Sarro Angelina; Thiemermann Christoph
5-Aminoisoquinolinone reduces colon injury by experimental colitis.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(6):464-73.
2004: Hauser Balázs; Radermacher Peter; Thiemermann Christoph; Matejovic Martin
Nitric oxide, bacteria, and host defense in sepsis: who needs what?
Shock (Augusta, Ga.) 2004;22(6):588-90.
2004: Abdelrahman Maha; Collin Marika; Thiemermann Christoph
The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 2004;22(6):555-61.
2004: Cuzzocrea Salvatore; Mazzon Emanuela; Di Paola Rosanna; Patel Nimesh S A; Genovese Tiziana; Muià Carmelo; De Sarro Angelina; Thiemermann Christoph
Erythropoietin reduces the development of experimental inflammatory bowel disease.
The Journal of pharmacology and experimental therapeutics 2004;311(3):1272-80.
2004: Collin Marika; Rossi Antonietta; Cuzzocrea Salvatore; Patel Nimesh S A; Di Paola Rosanna; Hadley Julia; Collino Massimo; Sautebin Lidia; Thiemermann Christoph
Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
Journal of leukocyte biology 2004;76(5):961-70.
2004: Chatterjee Prabal K; Todorovic Zoran; Sivarajah Ahila; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Thiemermann Christoph
Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.
European journal of pharmacology 2004;503(1-3):173-83.
2004: Pétrilli Virginie; Herceg Zdenko; Hassa Paul O; Patel Nimesh S A; Di Paola Rosanna; Cortes Ulrich; Dugo Laura; Filipe Helder-Mota; Thiemermann Christoph; Hottiger Michael O; Cuzzocrea Salvatore; Wang Zhao-Qi
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice.
The Journal of clinical investigation 2004;114(8):1072-81.
2004: Wang Jacob E; Pettersen Solveig; Stuestol Jon Fredrik; Wang Yun Yong; Foster Simon J; Thiemermann Christoph; Aasen Ansgar O; Bjørnland Kristin
Peptidoglycan of S. aureus causes increased levels of matrix metalloproteinases in the rat.
Shock (Augusta, Ga.) 2004;22(4):376-9.
2004: Dugo Laura; Collin Marika; Cuzzocrea Salvatore; Thiemermann Christoph
15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria.
European journal of pharmacology 2004;498(1-3):295-301.
2004: Patel Nimesh S A; Sharples Edward J; Cuzzocrea Salvatore; Chatterjee Prabal K; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo.
Kidney international 2004;66(3):983-9.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Caputi Achille P; Thiemermann Christoph
Tempol reduces the activation of nuclear factor-kappaB in acute inflammation.
Free radical research 2004;38(8):813-9.
2004: Patel Nimesh S A; Collin Marika; Thiemermann Christoph
Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion.
European journal of pharmacology 2004;496(1-3):175-80.
2004: Sharples Edward J; Patel Nimesh; Brown Paul; Stewart Keith; Mota-Philipe Helder; Sheaff Michael; Kieswich Julius; Allen David; Harwood Steven; Raftery Martin; Thiemermann Christoph; Yaqoob Muhammad M
Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.
Journal of the American Society of Nephrology : JASN 2004;15(8):2115-24.
2004: Patel Nimesh S A; Cuzzocrea Salvatore; Chatterjee Prabal K; Di Paola Rosanna; Sautebin Lidia; Britti Domenico; Thiemermann Christoph
Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
Molecular pharmacology 2004;66(2):220-7.
2004: Thiemermann Christoph
Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure.
British journal of pharmacology 2004;142(6):1049-51.
2004: Abdelrahman Maha; Sharples Edward J; McDonald Michelle C; Collin Marika; Patel Nimesh S A; Yaqoob Muhammad M; Thiemermann Christoph
Erythropoietin attenuates the tissue injury associated with hemorrhagic shock and myocardial ischemia.
Shock (Augusta, Ga.) 2004;22(1):63-9.
2004: Thiemermann Christoph
Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size.
Cardiovascular research 2004;63(1):8-10.
2004: Sepodes B; Maio R; Pinto R; Marques C; Mendes-do-Vale J; McDonald M C; Thiemermann C; Mota-Filipe H
Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat.
Transplantation proceedings 2004;36(4):849-53.
2004: Di Paola Rosanna; Genovese Tiziana; Caputi Achille P; Threadgill Mike; Thiemermann Christoph; Cuzzocrea Salvatore
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.
European journal of pharmacology 2004;492(2-3):203-10.
2004: Cuzzocrea Salvatore; Thiemermann Christoph; Salvemini Daniela
Potential therapeutic effect of antioxidant therapy in shock and inflammation.
Current medicinal chemistry 2004;11(9):1147-62.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Britti Domenico; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein.
Intensive care medicine 2004;30(5):951-6.
2004: Cuzzocrea Salvatore; Dugo Laura; Patel Nimesh S A; Di Paola Rosanna; Cockerill Gillian W; Genovese Tiziana; Thiemermann Christoph
High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis.
Shock (Augusta, Ga.) 2004;21(4):342-51.
2004: Al-Ghamdi Saeed S; Chatterjee Prabal K; Raftery Martin J; Thiemermann Christoph; Yaqoob Muhammad M
Role of cytochrome P4502E1 activation in proximal tubular cell injury induced by hydrogen peroxide.
Renal failure 2004;26(2):103-10.
2004: Collin Marika; Patel Nimesh S A; Dugo Laura; Thiemermann Christoph
Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin.
Critical care medicine 2004;32(3):826-31.
2004: Myhre Anders E; Stuestøl Jon Fredrik; Dahle Maria K; Øverland Gunhild; Thiemermann Christoph; Foster Simon J; Lilleaasen Per; Aasen Ansgar O; Wang Jacob E
Organ injury and cytokine release caused by peptidoglycan are dependent on the structural integrity of the glycan chain.
Infection and immunity 2004;72(3):1311-7.
2004: Wu Aihua; Hinds Charles J; Thiemermann Christoph
High-density lipoproteins in sepsis and septic shock: metabolism, actions, and therapeutic applications.
Shock (Augusta, Ga.) 2004;21(3):210-21.
2004: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Sharpe Martyn A; Di Paola Rosanna; Cuzzocrea Salvatore; Thiemermann Christoph
EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney.
American journal of nephrology 2004;24(2):165-77.
2004: Collin Marika; Abdelrahman Maha; Thiemermann Christoph
Endogenous ligands of PPAR-gamma reduce the liver injury in haemorrhagic shock.
European journal of pharmacology 2004;486(2):233-5.
2004: Chatterjee Prabal Kumar; Patel Nimesh S A; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Britti Domenico; Eberhardt Wolfgang; Pfeilschifter Josef; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.
Cardiovascular research 2004;61(3):630-43.
2004: Wang Jacob E; Dahle Maria K; Yndestad Arne; Bauer Inge; McDonald Michelle C; Aukrust Pål; Foster Simon J; Bauer Michael; Aasen Ansgar O; Thiemermann Christoph
Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat.
Critical care medicine 2004;32(2):546-52.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Chatterjee Prabal K; Fulia Francesco; Cuzzocrea Elisabetta; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice.
Critical care medicine 2004;32(2):457-66.
2004: Chatterjee Prabal K; Chatterjee Bristi E; Pedersen Helene; Sivarajah Ahila; McDonald Michelle C; Mota-Filipe Helder; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Threadgill Michael D; Thiemermann Christoph
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.
Kidney international 2004;65(2):499-509.
2004: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Maffia Pasquale; Patel Nimesh S A; Di Paola Rosanna; Ialenti Armando; Genovese Tiziana; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.
European journal of pharmacology 2004;483(1):79-93.
2004: Marzocco Stefania; Di Paola Rosanna; Autore Giuseppina; Mazzon Emanuela; Pinto Aldo; Caputi Achille P; Thiemermann Cristoph; Cuzzocrea Salvatore
Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat.
Shock (Augusta, Ga.) 2004;21(1):38-44.
2004: Thiemermann C
Ligands of the peroxisome proliferator-activated receptor-gamma and heart failure.
British journal of pharmacology 2004;141(1):1-3.
2003: Keller Thorsten; Plesková Miriam; McDonald Michelle C; Thiemermann Christoph; Pfeilschifter Josef; Beck Karl-Friedrich
Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresis.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;9(4):183-93.
2003: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Patel Nimesh S A; Serraino Ivana; Di Paola Rosanna; Genovese Tiziana; Britti Domenico; De Maio Massimo; Caputi Achille P; Thiemermann Christoph
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma.
Arthritis and rheumatism 2003;48(12):3544-56.
2003: Chatterjee Prabal K; di Villa Bianca Roberta D'Emmanuele; Sivarajah Ahila; McDonald Michelle C; Cuzzocrea Salvatore; Thiemermann Christoph
Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney.
European journal of pharmacology 2003;482(1-3):271-80.
2003: McDonald Michelle C; Dhadly Pal; Cockerill Gillian W; Cuzzocrea Salvatore; Mota-Filipe Helder; Hinds Charles J; Miller Norman E; Thiemermann Christoph
Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock.
Shock (Augusta, Ga.) 2003;20(6):551-7.
2003: Chatterjee Prabal K; Thiemermann Christoph
Emerging drugs for renal failure.
Expert opinion on emerging drugs 2003;8(2):389-435.
2003: Wang Jacob E; Dahle Maria K; McDonald Michelle; Foster Simon J; Aasen Ansgar O; Thiemermann Christoph
Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism.
Shock (Augusta, Ga.) 2003;20(5):402-14.
2003: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Brown Paul A J; Stewart Keith N; Britti Domenico; Cuzzocrea Salvatore; Mota-Filipe Helder; Thiemermann Christoph
The tyrosine kinase inhibitor tyrphostin AG126 reduces renal ischemia/reperfusion injury in the rat.
Kidney international 2003;64(5):1605-19.
2003: Cuzzocrea Salvatore; Rossi Antonietta; Pisano Barbara; Di Paola Rosanna; Genovese Tiziana; Patel Nimesh S A; Cuzzocrea Elisabetta; Ianaro Angela; Sautebin Lidia; Fulia Francesco; Chatterjee Prabal K; Caputi Achille P; Thiemermann Christoph
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice.
Intensive care medicine 2003;29(11):2016-25.
2003: Chatterjee Prabal K; Kvale Espen O; Patel Nimesh S A; Thiemermann Christoph
GW274150 inhibits nitric oxide production by primary cultures of rat proximal tubular cells.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(10):BR357-62.
2003: Muscoli Carolina; Cuzzocrea Salvatore; Riley Dennis P; Zweier Jay L; Thiemermann Christoph; Wang Zhi-Qiang; Salvemini Daniela
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies.
British journal of pharmacology 2003;140(3):445-60.
2003: Cuzzocrea Salvatore; Pisano Barbara; Dugo Laura; Ianaro Angela; Patel Nimesh S A; Di Paola Rosanna; Genovese Tiziana; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
British journal of pharmacology 2003;140(2):366-76.
2003: McDonald Michelle; Abdelrahman Maha; Cuzzocrea Salvatore; Thiemermann Christoph
Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase.
Resuscitation 2003;58(3):349-61.
2003: Collin Marika; Thiemermann Christoph
The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock.
European journal of pharmacology 2003;476(3):257-8.
2003: Wang Yun; Chang Chen-Fu; Morales Marisela; Chiang Yung-Hsiao; Harvey Brandon K; Su Tsung-Ping; Tsao Li-I; Chen Suyu; Thiemermann Christoph
Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(21):7958-65.
2003: Sivarajah Ahila; Chatterjee Prabal K; Patel Nimesh S A; Todorovic Zoran; Hattori Yoshiyuki; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Cuzzocrea Salvatore; Thiemermann Christoph
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury.
American journal of nephrology 2003;23(4):267-76.
2003: Thiemermann Christoph; Patel Nimesh S A; Kvale Espen O; Cockerill Gillian W; Brown Paul A J; Stewart Keith N; Cuzzocrea Salvatore; Britti Domenico; Mota-Filipe Helder; Chatterjee Prabal K
High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury.
Journal of the American Society of Nephrology : JASN 2003;14(7):1833-43.
2003: Wayman Nicole S; Ellis Belinda L; Thiemermann Christoph
Simvastatin reduces infarct size in a model of acute myocardial ischemia and reperfusion in the rat.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(5):BR155-9.
2003: McDonald Michelle C; d'Emmanuele di Villa Bianca Roberta; Wayman Nicole S; Pinto Aldo; Sharpe Martyn A; Cuzzocrea Salvatore; Chatterjee Prabal K; Thiemermann Christoph
A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock.
European journal of pharmacology 2003;466(1-2):181-9.
2003: Chatterjee Prabal K; Patel Nimesh S A; Sivarajah Ahila; Kvale Espen O; Dugo Laura; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Britti Domenico; Yaqoob Muhammad M; Thiemermann Christoph
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.
Kidney international 2003;63(3):853-65.
2003: Cuzzocrea Salvatore; Ianaro Angela; Wayman Nicole S; Mazzon Emanuela; Pisano Barbara; Dugo Laura; Serraino Ivana; Di Paola Rosanna; Chatterjee Prabal K; Di Rosa Massimo; Caputi Achille P; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.
British journal of pharmacology 2003;138(4):678-88.
2003: Thiemermann Christoph
Protein tyrosine kinase inhibitors as novel therapeutics for systemic inflammation, shock, and organ injury.
Critical care medicine 2003;31(2):652-3.
2003: Thiemermann Christoph
Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation.
Critical care medicine 2003;31(1 Suppl):S76-84.
2003: Øverland Gunhild; Morath Sigfried; Yndestad Arne; Hartung Thomas; Thiemermann Christoph; Foster Simon J; Smedsrød Bård; Mathisen Øystein; Aukrust Pål; Aasen Ansgar O; Wang Jacob E
Lipoteichoic acid is a potent inducer of cytokine production in rat and human Kupffer cells in vitro.
Surgical infections 2003;4(2):181-91.
2003: Chatterjee Prabal K; Thiemermann Christoph
An in vivo model of ischemia/reperfusion and inflammation of the kidneys of the rat.
Methods in molecular biology (Clifton, N.J.) 2003;225():223-37.
2003: Wayman Nicole S; McDonald Michelle C; Chatterjee Prabal K; Thiemermann Christoph
Models of coronary artery occlusion and reperfusion for the discovery of novel antiischemic and antiinflammatory drugs for the heart.
Methods in molecular biology (Clifton, N.J.) 2003;225():199-208.
2002: McDonald M C; Izumi M; Cuzzocrea S; Thiemermann C
A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2002;53(4 Pt 1):555-69.
2002: Sivarajah Ahila; Chatterjee Prabal K; Hattori Yoshiyuki; Brown Paul A; Stewart Keith N; Todorovic Zoran; Mota-Filipe Helder; Thiemermann Christoph
Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(12):BR532-9.
2002: Patel Nimesh S A; Chatterjee Prabal K; Chatterjee Bristi E; Cuzzocrea Salvatore; Serraino Ivana; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney.
Free radical biology & medicine 2002;33(11):1575-89.
2002: Mota-Filipe Helder; Sepodes Bruno; McDonald Michelle C; Cuzzocrea Salvatore; Pinto Rui; Thiemermann Christoph
The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(11):BR444-53.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Serraino Ivana; Dugo Laura; Centorrino Tommaso; Barbera Alberto; Ciccolo Antonio; Fulia Francesco; McDonald Michelle C; Caputi Achille P; Thiemermann Christoph
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.
Critical care medicine 2002;30(10):2284-94.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; McDonald Michelle C; Dugo Laura; Di Paola Rosanna; Serraino Ivana; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis.
European journal of pharmacology 2002;453(1):119-29.
2002: Chatterjee Prabal K; Zacharowski Kai; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury.
Kidney international 2002;62(4):1249-63.
2002: Thiemermann Christoph
A vaccine to prevent infections with Staphylococcus aureus.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(9):LE35-6.
2002: Izumi Maya; McDonald Michelle C; Sharpe Martyn A; Chatterjee Prabal K; Thiemermann Christoph
Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 2002;18(3):230-5.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Dugo Laura; De Sarro Angela; Van de Loo Fons A J; Caputi Achille P; Thiemermann Christoph
Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury.
Shock (Augusta, Ga.) 2002;18(2):169-76.
2002: Wayman Nicole S; Ellis Belinda L; Thiemermann Christoph
Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(7):BR243-7.
2002: Thiemermann Christoph
Interactions between lipoteichoic acid and peptidoglycan from Staphylococcus aureus: a structural and functional analysis.
Microbes and infection / Institut Pasteur 2002;4(9):927-35.
2002: Millar Colin G M; Thiemermann Christoph
Carboxy-PTIO, a scavenger of nitric oxide, selectively inhibits the increase in medullary perfusion and improves renal function in endotoxemia.
Shock (Augusta, Ga.) 2002;18(1):64-8.
2002: Wayman Nicole S; Hattori Yoshiyuki; McDonald Michelle C; Mota-Filipe Helder; Cuzzocrea Salvatore; Pisano Babrbara; Chatterjee Prabal K; Thiemermann Christoph
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(9):1027-40.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Centorrino Tommaso; Ciccolo Antonio; McDonald Michelle C; de Sarro Agelina; Caputi Achille P; Thiemermann Christoph
Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice.
Cytokine 2002;18(5):274-85.
2002: Dugo L; Chatterjee P K; Mazzon E; McDonald M C; Paola R Di; Fulia F; Caputi A P; Thiemermann C; Cuzzocrea S
The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat.
Intensive care medicine 2002;28(6):775-88.
2002: Cuzzocrea Salvatore; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Centorrino Tommaso; Ciccolo Antonio; Van de Loo Fons A J; Britti Domenico; Caputi Achille P; Thiemermann Christoph
Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein.
Shock (Augusta, Ga.) 2002;17(5):416-22.
2002: Ellingsen Espen; Morath Siegfried; Flo Trude; Schromm Andra; Hartung Thomas; Thiemermann Christoph; Espevik Terje; Golenbock Douglas; Foster Daniel; Solberg Rigmor; Aasen Ansgar; Wang Jacob
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(5):BR149-56.
2002: Thiemermann Christoph
Development of novel, water-soluble inhibitors of poly (adenosine 5'-diphosphate ribose) synthetase activity for use in shock and ischemia-reperfusion injury.
Critical care medicine 2002;30(5):1163-5.
2002: Cuzzocrea Salvatore; Wayman Nicole S; Mazzon Emanuela; Dugo Laura; Di Paola Rosanna; Serraino Ivana; Britti Domenico; Chatterjee Prabal K; Caputi Achille P; Thiemermann Christoph
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.
Molecular pharmacology 2002;61(5):997-1007.
2002: Chatterjee Prabal K; Patel Nimesh S A; Kvale Espen O; Cuzzocrea Salvatore; Brown Paul A J; Stewart Keith N; Mota-Filipe Helder; Thiemermann Christoph
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury.
Kidney international 2002;61(3):862-71.
2002: Cuzzocrea Salvatore; McDonald Michelle C; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Threadgill Mike; Caputi Achille P; Thiemermann Christoph
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.
Biochemical pharmacology 2002;63(2):293-304.
2002: Cuzzocrea Salvatore; Chatterjee Prabal K; Mazzon Emanuela; Dugo Laura; Serraino Ivana; Britti Domenico; Mazzullo Giuseppe; Caputi Achille P; Thiemermann Christoph
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation.
British journal of pharmacology 2002;135(2):496-510.
2002: Bianca Roberta d'Emmanuele di Villa; Wayman Nicole S; McDonald Michelle C; Pinto Aldo; Shape Martyn A; Chatterjee Prabal K; Thiemermann Christoph
Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(1):BR1-7.
2002: Zacharowski Kai; Chatterjee Prabal K; Thiemermann Christoph
Delayed preconditioning induced by lipoteichoic acid from B. subtilis and S. aureus is not blocked by administration of 5-hydroxydecanoate.
Shock (Augusta, Ga.) 2002;17(1):19-22.
2001: Wayman N; McDonald M C; Thompson A S; Threadgill M D; Thiemermann C
5-aminoisoquinolinone, a potent inhibitor of poly (adenosine 5'-diphosphate ribose) polymerase, reduces myocardial infarct size.
European journal of pharmacology 2001;430(1):93-100.
2001: Cockerill G W; McDonald M C; Mota-Filipe H; Cuzzocrea S; Miller N E; Thiemermann C
High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):1941-52.
2001: Wang J E; Jørgensen P F; Ellingsen E A; Almiöf M; Thiemermann C; Foster S J; Aasen A O; Solberg R
Peptidoglycan primes for LPS-induced release of proinflammatory cytokines in whole human blood.
Shock (Augusta, Ga.) 2001;16(3):178-82.
2001: Zacharowski K; Berkels R; Olbrich A; Chatterjee P K; Cuzzocrea S; Foster S J; Thiemermann C
The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock.
Critical care medicine 2001;29(8):1599-608.
2001: Chatterjee P K; Brown P A; Cuzzocrea S; Zacharowski K; Stewart K N; Mota-Filipe H; McDonald M C; Thiemermann C
Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat.
Kidney international 2001;59(6):2073-83.
2001: Jørgensen P F; Wang J E; Almlöf M; Thiemermann C; Foster S J; Solberg R; Aasen A O
Peptidoglycan and lipoteichoic acid modify monocyte phenotype in human whole blood.
Clinical and diagnostic laboratory immunology 2001;8(3):515-21.
2001: Cuzzocrea S; McDonald M C; Mazzon E; Mota-Filipe H; Centorrino T; Terranova M L; Ciccolo A; Britti D; Caputi A P; Thiemermann C
Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat.
Gut 2001;48(4):478-88.
2001: Jørgensen P F; Wang J E; Solberg R; Thiemermann C; Foster S J; Aasen A O
Procalcitonin does not influence the surface expression of inflammatory receptors on whole blood leukocytes.
Intensive care medicine 2001;27(2):430-3.
2001: Wray G M; Foster S J; Hinds C J; Thiemermann C
A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat.
Shock (Augusta, Ga.) 2001;15(2):135-42.
2001: Jørgensen P F; Wang J E; Almlöf M; Solberg R; Okkenhaug C; Scholz T; Thiemermann C; Foster S J; Aasen A O
Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production.
Scandinavian journal of immunology 2001;53(2):184-91.
2001: Cuzzocrea S; McDonald M C; Mazzon E; Filipe H M; Centorrino T; Lepore V; Terranova M L; Ciccolo A; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat.
Critical care medicine 2001;29(1):102-11.
2001: McDonald M C; Mota-Filipe H; Paul A; Cuzzocrea S; Abdelrahman M; Harwood S; Plevin R; Chatterjee P K; Yaqoob M M; Thiemermann C
Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):171-186.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Serraino I; Dugo L; Britti D; Mazzullo G; Caputi A P; Thiemermann C
Calpain inhibitor I reduces the development of acute and chronic inflammation.
The American journal of pathology 2000;157(6):2065-79.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Dugo L; Lepore V; Fonti M T; Ciccolo A; Terranova M L; Caputi A P; Thiemermann C
Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis.
European journal of pharmacology 2000;406(1):127-37.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Mota-Filipe H; Lepore V; Ciccolo A; Terranova M L; Britti D; Caputi A P; Thiemermann C
The tyrosine kinase inhibitor tyrphostin AG 126 reduced the development of colitis in the rat.
Laboratory investigation; a journal of technical methods and pathology 2000;80(9):1439-53.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Costantino G; Fulia F; Cucinotta G; Gitto E; Cordaro S; Barberi I; De Sarro A; Caputi A P; Thiemermann C
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
Brain research 2000;875(1-2):96-106.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Filipe H M; Costantino G; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion.
Shock (Augusta, Ga.) 2000;14(2):150-6.
2000: Chatterjee P K; Cuzzocrea S; Brown P A; Zacharowski K; Stewart K N; Mota-Filipe H; Thiemermann C
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.
Kidney international 2000;58(2):658-73.
2000: Thiemermann C; Zacharowski K
Selective activation of E-type prostanoid(3)-receptors reduces myocardial infarct size. A novel insight into the cardioprotective effects of prostaglandins.
Pharmacology & therapeutics 2000;87(1):61-7.
2000: Cuzzocrea S; McDonald M C; Mazzon E; Siriwardena D; Calabrò G; Britti D; Mazzullo G; De Sarro A; Caputi A P; Thiemermann C
The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation.
The American journal of pathology 2000;157(1):145-58.
2000: Wang J E; Jørgensen P F; Almlöf M; Thiemermann C; Foster S J; Aasen A O; Solberg R
Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor alpha, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model.
Infection and immunity 2000;68(7):3965-70.
2000: Zacharowski K; Olbrich A; Cuzzocrea S; Foster S J; Thiemermann C
Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of gram-positive shock.
Critical care medicine 2000;28(6):1953-61.
2000: McDonald M C; Mota-Filipe H; Wright J A; Abdelrahman M; Threadgill M D; Thompson A S; Thiemermann C
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock.
British journal of pharmacology 2000;130(4):843-50.
2000: Zacharowski K; Frank S; Otto M; Chatterjee P K; Cuzzocrea S; Hafner G; Pfeilschifter J; Thiemermann C
Lipoteichoic acid induces delayed protection in the rat heart: A comparison with endotoxin.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1521-8.
2000: Chatterjee P K; Zacharowski K; Cuzzocrea S; Otto M; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):641-51.
2000: Walpen S; Beck K F; Eberhardt W; Apel M; Chatterjee P K; Wray G M; Thiemermann C; Pfeilschifter J
Downregulation of SPARC expression is mediated by nitric oxide in rat mesangial cells and during endotoxemia in the rat.
Journal of the American Society of Nephrology : JASN 2000;11(3):468-76.
2000: Cuzzocrea S; McDonald M C; Filipe H M; Costantino G; Mazzon E; Santagati S; Caputi A P; Thiemermann C
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy.
European journal of pharmacology 2000;390(1-2):209-22.
2000: Cuzzocrea S; McDonald M C; Mota-Filipe H; Mazzon E; Costantino G; Britti D; Mazzullo G; Caputi A P; Thiemermann C
Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of collagen-induced arthritis.
Arthritis and rheumatism 2000;43(2):320-8.
1999: McDonald M C; Filipe H M; Thiemermann C
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
British journal of pharmacology 1999;128(6):1339-45.
1999: Zacharowski K; Otto M; Hafner G; Marsh H C; Thiemermann C
Reduction of myocardial infarct size with sCR1sLe(x), an alternatively glycosylated form of human soluble complement receptor type 1 (sCR1), possessing sialyl Lewis x.
British journal of pharmacology 1999;128(5):945-52.
1999: Cuzzocrea S; Sautebin L; De Sarro G; Costantino G; Rombolà L; Mazzon E; Ialenti A; De Sarro A; Ciliberto G; Di Rosa M; Caputi A P; Thiemermann C
Role of IL-6 in the pleurisy and lung injury caused by carrageenan.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):5094-104.
1999: Mota-Filipe H; McDonald M C; Cuzzocrea S; Thiemermann C
A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock.
Shock (Augusta, Ga.) 1999;12(4):255-61.
1999: McDonald M C; Zacharowski K; Bowes J; Cuzzocrea S; Thiemermann C
Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusion.
Free radical biology & medicine 1999;27(5-6):493-503.
1999: Zacharowski K; Otto M; Hafner G; Chatterjee P K; Thiemermann C
Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(9):2276-80.
1999: Zacharowski K; Olbrich A; Piper J; Hafner G; Kondo K; Thiemermann C
Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(9):2141-7.
1999: Chatterjee P K; Cuzzocrea S; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.
Kidney international 1999;56(3):973-84.
1999: Frank S; Zacharowski K; Wray G M; Thiemermann C; Pfeilschifter J
Identification of copper/zinc superoxide dismutase as a novel nitric oxide-regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):869-82.
1999: Zacharowski K; Olbrich A; Otto M; Hafner G; Thiemermann C
Effects of the prostanoid EP3-receptor agonists M&B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat.
British journal of pharmacology 1999;126(4):849-58.
1999: Zacharowski K; Olbrich A; Thiemermann C
Reduction of myocardial injury by the EP3 receptor agonist TEI-3356. Role of protein kinase C and of K(ATP)-channels.
European journal of pharmacology 1999;367(1):33-9.
1999: Bowes J; McDonald M C; Piper J; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress.
Cardiovascular research 1999;41(1):126-34.
1998: Chatterjee P K; Thiemermann C
Inhibitors of poly (ADP-ribose) synthetase protect rat renal proximal tubular cells against oxidant stress.
Biochemical Society transactions 1998;26(4):S318.
1998: Bowes J; Ruetten H; Martorana P A; Stockhausen H; Thiemermann C
Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig.
European journal of pharmacology 1998;359(2-3):143-50.
1998: Leach M; Frank S; Olbrich A; Pfeilschifter J; Thiemermann C
Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: effects of the superoxide anion radical scavenger, tempol, on organ injury.
British journal of pharmacology 1998;125(4):817-25.
1998: Bowes J; Piper J; Thiemermann C
Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts.
British journal of pharmacology 1998;124(8):1760-6.
1998: Bowes J; Thiemermann C
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the liver injury caused by ischaemia-reperfusion: a comparison with radical scavengers.
British journal of pharmacology 1998;124(6):1254-60.
1998: Wray G M; Hinds C J; Thiemermann C
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Shock (Augusta, Ga.) 1998;10(1):13-9.
1998: Kengatharan K M; De Kimpe S; Robson C; Foster S J; Thiemermann C
Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failure.
The Journal of experimental medicine 1998;188(2):305-15.
1998: Leach M; Hamilton L C; Olbrich A; Wray G M; Thiemermann C
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.
British journal of pharmacology 1998;124(3):586-92.
1998: Wray G M; Millar C G; Hinds C J; Thiemermann C
Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin.
Shock (Augusta, Ga.) 1998;9(5):329-35.
1998: Saetre T; Gundersen Y; Thiemermann C; Lilleaasen P; Aasen A O
Aminoethyl-isothiourea, a selective inhibitor of inducible nitric oxide synthase activity, improves liver circulation and oxygen metabolism in a porcine model of endotoxemia.
Shock (Augusta, Ga.) 1998;9(2):109-15.
1997: Ruetten H; Thiemermann C
Endothelin-1 stimulates the biosynthesis of tumour necrosis factor in macrophages: ET-receptors, signal transduction and inhibition by dexamethasone.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1997;48(4):675-88.
1997: Ruetten H; Thiemermann C
Combination immunotherapy which neutralises the effects of TNF alpha and IL-1 beta attenuates the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 1997;48(4):605-21.
1997: Ruetten H; Thiemermann C
Interleukin-13 is a more potent inhibitor of the expression of inducible nitric oxide synthase in smooth muscle cells than in macrophages: a comparison with interleukin-4 and interleukin-10.
Shock (Augusta, Ga.) 1997;8(6):409-14.
1997: Ruetten H; Thiemermann C
Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase.
British journal of pharmacology 1997;122(1):59-70.
1997: Millar C G; Thiemermann C
Intrarenal haemodynamics and renal dysfunction in endotoxaemia: effects of nitric oxide synthase inhibition.
British journal of pharmacology 1997;121(8):1824-30.
1997: Ruetten H; Thiemermann C
Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.
British journal of pharmacology 1997;121(4):695-704.
1997: Thiemermann C; Bowes J; Myint F P; Vane J R
Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):679-83.
1996: Kengatharan K M; De Kimpe S J; Thiemermann C
Role of nitric oxide in the circulatory failure and organ injury in a rodent model of gram-positive shock.
British journal of pharmacology 1996;119(7):1411-21.
1996: Ruetten H; Thiemermann C
Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat.
British journal of pharmacology 1996;119(3):479-86.
1996: Ruetten H; Thiemermann C
Prevention of the expression of inducible nitric oxide synthase by aminoguanidine or aminoethyl-isothiourea in macrophages and in the rat.
Biochemical and biophysical research communications 1996;225(2):525-30.
1996: Hide E J; Thiemermann C
Sulprostone-induced reduction of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels.
British journal of pharmacology 1996;118(6):1409-14.
1996: Hide E J; Thiemermann C
Limitation of myocardial infarct size in the rabbit by ischaemic preconditioning is abolished by sodium 5-hydroxydecanoate.
Cardiovascular research 1996;31(6):941-6.
1996: Ruetten H; Southan G J; Abate A; Thiemermann C
Attenuation of endotoxin-induced multiple organ dysfunction by 1-amino-2-hydroxy-guanidine, a potent inhibitor of inducible nitric oxide synthase.
British journal of pharmacology 1996;118(2):261-70.
1996: Ruetten H; Thiemermann C; Vane J R
Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat.
British journal of pharmacology 1996;118(1):198-204.
1996: Wu C C; Ruetten H; Thiemermann C
Comparison of the effects of aminoguanidine and N omega-nitro-L-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat.
European journal of pharmacology 1996;300(1-2):99-104.
1996: Kengatharan M; De Kimpe S J; Thiemermann C
Analysis of the signal transduction in the induction of nitric oxide synthase by lipoteichoic acid in macrophages.
British journal of pharmacology 1996;117(6):1163-70.
1996: Akarasereenont P; Thiemermann C
The induction of cyclo-oxygenase-2 in human pulmonary epithelial cell culture (A549) activated by IL-1beta is inhibited by tyrosine kinase inhibitors.
Biochemical and biophysical research communications 1996;220(1):181-5.
1995: Hohlfeld T; Klemm P; Thiemermann C; Warner T D; Schrör K; Vane J R
The contribution of tumour necrosis factor-alpha and endothelin-1 to the increase of coronary resistance in hearts from rats treated with endotoxin.
British journal of pharmacology 1995;116(8):3309-15.
1995: De Kimpe S J; Thiemermann C; Vane J R
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock.
British journal of pharmacology 1995;116(8):3191-8.
1995: Thiemermann C; Ruetten H; Wu C C; Vane J R
The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase.
British journal of pharmacology 1995;116(7):2845-51.
1995: Hide E J; Piper J; Thiemermann C
Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.
British journal of pharmacology 1995;116(6):2597-602.
1995: Hide E J; Ney P; Piper J; Thiemermann C; Vane J R
Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels.
British journal of pharmacology 1995;116(5):2435-40.
1995: Hattori Y; Szabó C; Gross S; Thiemermann C; Vane J R
Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo.
European journal of pharmacology 1995;291(2):83-90.
1995: De Kimpe S J; Kengatharan M; Thiemermann C; Vane J R
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10359-63.
1995: Klemm P; Hecker M; Stockhausen H; Wu C C; Thiemermann C
Inhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized rat.
British journal of pharmacology 1995;115(7):1175-81.
1995: Akarasereenont P; Bakhle Y S; Thiemermann C; Vane J R
Cytokine-mediated induction of cyclo-oxygenase-2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide.
British journal of pharmacology 1995;115(3):401-8.
1995: Wu C C; Chen S J; Szabó C; Thiemermann C; Vane J R
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
British journal of pharmacology 1995;114(8):1666-72.
1995: De Kimpe S J; Hunter M L; Bryant C E; Thiemermann C; Vane J R
Delayed circulatory failure due to the induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in anaesthetized rats.
British journal of pharmacology 1995;114(6):1317-23.
1995: Wu C C; Thiemermann C; Vane J R
Glibenclamide-induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anaesthetized rat.
British journal of pharmacology 1995;114(6):1273-81.
1995: Akarasereenont P; Mitchell J A; Bakhle Y S; Thiemermann C; Vane J R
Comparison of the induction of cyclooxygenase and nitric oxide synthase by endotoxin in endothelial cells and macrophages.
European journal of pharmacology 1995;273(1-2):121-8.
1995: Southan G J; Szabó C; Thiemermann C
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity.
British journal of pharmacology 1995;114(2):510-6.
1995: Kengatharan M; Battistini B; Warner T D; Thiemermann C; Vane J R
Endothelin-1 mediates the increase in ex vivo coronary vascular resistance induced by hemorrhagic shock in the anesthetized rat.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S422-4.
1995: Szabó C; Thiemermann C
Regulation of the expression of the inducible isoform of nitric oxide synthase.
Advances in pharmacology (San Diego, Calif.) 1995;34():113-53.
1995: Thiemermann C
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
Progress in clinical and biological research 1995;392():383-92.
1995: Akarasereenont P; Hide E; Ney P; Thiemermann C; Vane J R
The induction of cyclooxygenase-2 elicited by endotoxin in endothelial cells and macrophages is inhibited by prostaglandin E1 and 13,14-dihydro prostaglandin E1.
Agents and actions. Supplements 1995;45():59-64.
1994: Akarasereenont P; Mitchell J A; Appleton I; Thiemermann C; Vane J R
Involvement of tyrosine kinase in the induction of cyclo-oxygenase and nitric oxide synthase by endotoxin in cultured cells.
British journal of pharmacology 1994;113(4):1522-8.
1994: Szabó C; Southan G J; Thiemermann C
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12472-6.
1994: Szabó C; Southan G J; Thiemermann C; Vane J R
The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites.
British journal of pharmacology 1994;113(3):757-66.
1994: Southan G J; Szabó C; Thiemermann C
Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase.
Biochemical and biophysical research communications 1994;203(3):1638-44.
1994: Szabó C; Thiemermann C
Invited opinion: role of nitric oxide in hemorrhagic, traumatic, and anaphylactic shock and thermal injury.
Shock (Augusta, Ga.) 1994;2(2):145-55.
1994: McMurdo L; Thiemermann C; Vane J R
The endothelin ETB receptor agonist, IRL 1620, causes vasodilatation and inhibits ex vivo platelet aggregation in the anaesthetised rabbit.
European journal of pharmacology 1994;259(1):51-5.
1994: Szabó C; Southan G J; Wood E; Thiemermann C; Vane J R
Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor.
British journal of pharmacology 1994;112(2):355-6.
1994: McMurdo L; Thiemermann C; Vane J R
The effects of the endothelin ETA receptor antagonist, FR 139317, on infarct size in a rabbit model of acute myocardial ischaemia and reperfusion.
British journal of pharmacology 1994;112(1):75-80.
1994: Wu C C; Szabó C; Chen S J; Thiemermann C; Vane J R
Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin.
Biochemical and biophysical research communications 1994;201(1):436-42.
1994: Wellings R P; Corder R; Warner T D; Cristol J P; Thiemermann C; Vane J R
Evidence from receptor antagonists of an important role for ETB receptor-mediated vasoconstrictor effects of endothelin-1 in the rat kidney.
British journal of pharmacology 1994;111(2):515-20.
1994: Szabó C; Thiemermann C; Wu C C; Perretti M; Vane J R
Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):271-5.
1994: Thiemermann C
The role of the L-arginine: nitric oxide pathway in circulatory shock.
Advances in pharmacology (San Diego, Calif.) 1994;28():45-79.
1993: Thiemermann C
Drugs which modulate nitric oxide homeostasis are likely to provide therapeutic benefit in cardiovascular disease.
Cardiovascular research 1993;27(12):2104.
1993: Mitchell J A; Akarasereenont P; Thiemermann C; Flower R J; Vane J R
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11693-7.
1993: Szabó C; Wu C C; Mitchell J A; Gross S S; Thiemermann C; Vane J R
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide.
Circulation research 1993;73(6):991-9.
1993: Szabó C; Wu C C; Gross S S; Thiemermann C; Vane J R
Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo.
European journal of pharmacology 1993;250(1):157-60.
1993: Szabó C; Thiemermann C; Vane J R
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Biochemical and biophysical research communications 1993;196(2):825-30.
1993: Szabó C; Thiemermann C; Vane J R
Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats.
Proceedings. Biological sciences / The Royal Society 1993;253(1338):233-8.
1993: Thiemermann C; Wu C C; Szabó C; Perretti M; Vane J R
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock.
British journal of pharmacology 1993;110(1):177-82.
1993: McMurdo L; Lidbury P S; Thiemermann C; Vane J R
Mediation of endothelin-1-induced inhibition of platelet aggregation via the ETB receptor.
British journal of pharmacology 1993;109(2):530-4.
1993: Szabó C; Mitchell J A; Gross S S; Thiemermann C; Vane J R
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.
The Journal of pharmacology and experimental therapeutics 1993;265(2):674-80.
1993: Cristol J P; Thiemermann C; Mitchell J A; Walder C; Vane J R
Support of renal blood flow after ischaemic-reperfusion injury by endogenous formation of nitric oxide and of cyclo-oxygenase vasodilator metabolites.
British journal of pharmacology 1993;109(1):188-94.
1993: Cristol J P; Warner T D; Thiemermann C; Vane J R
Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat.
British journal of pharmacology 1993;108(3):776-9.
1993: Szabó C; Mitchell J A; Thiemermann C; Vane J R
Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock.
British journal of pharmacology 1993;108(3):786-92.
1993: McMurdo L; Corder R; Thiemermann C; Vane J R
Incomplete inhibition of the pressor effects of endothelin-1 and related peptides in the anaesthetized rat with BQ-123 provides evidence for more than one vasoconstrictor receptor.
British journal of pharmacology 1993;108(2):557-61.
1993: Thiemermann C; Szabó C; Mitchell J A; Vane J R
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):267-71.
1993: McMurdo L; Lidbury P S; Corder R; Thiemermann C; Vane J R
Heterogeneous receptors mediate endothelin-1-induced changes in blood pressure, hematocrit, and platelet aggregation.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S185-8.
1993: Wellings R P; Warner T D; Thiemermann C; Cristol J P; Corder R; Vane J R
Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145065.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S103-6.
1992: Walder C E; Thiemermann C; Vane J R
NG-hydroxy-L-arginine prevents the haemodynamic effects of nitric oxide synthesis inhibition in the anaesthetized rat.
British journal of pharmacology 1992;107(2):476-80.
1992: Sprague R S; Thiemermann C; Vane J R
Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8711-5.
1991: Thiemermann C; Mustafa M; Mester P A; Mitchell J A; Hecker M; Vane J R
Inhibition of the release of endothelium-derived relaxing factor in vitro and in vivo by dipeptides containing NG-nitro-L-arginine.
British journal of pharmacology 1991;104(1):31-8.
1991: Walder C E; Thiemermann C; Vane J R
The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat.
British journal of pharmacology 1991;102(4):967-73.
1991: Thiemermann C; al-Damluji S; Hecker M; Vane J R
FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system.
Biochemical and biophysical research communications 1991;175(1):318-24.
1991: Thiemermann C
Biosynthesis and interaction of endothelium-derived vasoactive mediators.
Eicosanoids 1991;4(4):187-202.
1990: Lidbury P S; Thiemermann C; Korbut R; Vane J R
Endothelins release tissue plasminogen activator and prostanoids.
European journal of pharmacology 1990;186(2-3):205-12.
1990: Walder C E; Thiemermann C; Vane J R
Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa.
Proceedings. Biological sciences / The Royal Society 1990;241(1302):195-200.
1990: Thiemermann C; Vane J
Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo.
European journal of pharmacology 1990;182(3):591-5.
1990: Hecker M; Mitchell J A; Harris H J; Katsura M; Thiemermann C; Vane J R
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine.
Biochemical and biophysical research communications 1990;167(3):1037-43.
1990: Thiemermann C; May G R; Page C P; Vane J R
Endothelin-1 inhibits platelet aggregation in vivo: a study with 111indium-labelled platelets.
British journal of pharmacology 1990;99(2):303-8.
1990: Thomas G R; Walder C E; Thiemermann C; Vane J R
Regional vascular resistance and haemodynamics in the spontaneously hypertensive rat: the effects of bradykinin.
Journal of cardiovascular pharmacology 1990;15(2):211-7.
1989: Lidbury P S; Thiemermann C; Thomas G R; Vane J R
Endothelin-3: selectivity as an anti-aggregatory peptide in vivo.
European journal of pharmacology 1989;166(2):335-8.
1989: Thiemermann C; Thomas G R; Vane J R
Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion.
British journal of pharmacology 1989;97(2):401-8.
1989: Thiemermann C; Thomas G R; Vane J R
Effects of defibrotide on infarct size and regional myocardial blood flow on the ischaemic reperfused rabbit heart.
Progress in clinical and biological research 1989;301():131-5.
1989: Walder C E; Thomas G R; Thiemermann C; Vane J R
The hemodynamic effects of endothelin-1 in the pithed rat.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S93-7; discussion S102.
1989: Thiemermann C; Lidbury P S; Thomas G R; Vane J R
Endothelin-1 releases prostacyclin and inhibits ex vivo platelet aggregation in the anesthetized rabbit.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S138-41; discussion S142.
1988: Thiemermann C; Lidbury P; Thomas R; Vane J
Endothelin inhibits ex vivo platelet aggregation in the rabbit.
European journal of pharmacology 1988;158(1-2):181-2.
1988: Thomas G R; Thiemermann C; Walder C; Vane J R
The effects of endothelium-dependent vasodilators on cardiac output and their distribution in the anaesthetized rat: a comparison with sodium nitroprusside.
British journal of pharmacology 1988;95(3):986-92.

Sign-in to see more