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John Th'ng

Research Profile

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Publications

TOP 3
P L Rapley; K Rich; M L Tassotto; S Niccoli; C Witiw; John Th'ng
In vitro molecular magnetic resonance imaging detection and measurement of apoptosis using superparamagnetic iron oxide + antibody as ligands for nucleosomes.
Melanie Heney; Misagh Alipour; Dimitrios Vergidis; abdel Omri; Clement Mugabe; John Th'ng; Zacharias Suntres
Effectiveness of liposomal paclitaxel against MCF-7 breast cancer cells.
Nikhil Raghuram; Gustavo Carrero; Timothy J Stasevich; James G McNally; John Th'ng; Michael Hendzel
Core histone hyperacetylation impacts cooperative behavior and high-affinity binding of histone H1 to chromatin.

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All Publications

2012: P L Rapley; K Rich; M L Tassotto; S Niccoli; C Witiw; John Th'ng
In vitro molecular magnetic resonance imaging detection and measurement of apoptosis using superparamagnetic iron oxide + antibody as ligands for nucleosomes.
Physics in medicine and biology 2012;57(21):7015-28.
2010: Melanie Heney; Misagh Alipour; Dimitrios Vergidis; abdel Omri; Clement Mugabe; John Th'ng; Zacharias Suntres
Effectiveness of liposomal paclitaxel against MCF-7 breast cancer cells.
Canadian journal of physiology and pharmacology 2010;88(12):1172-80.
2010: Nikhil Raghuram; Gustavo Carrero; Timothy J Stasevich; James G McNally; John Th'ng; Michael Hendzel
Core histone hyperacetylation impacts cooperative behavior and high-affinity binding of histone H1 to chromatin.
Biochemistry 2010;49(21):4420-31.
2009: Matthew J Kaskiw; Mary Lynn Tassotto; Mac Mok; Stacey L Tokar; Roxanne Pycko; John Th'ng; Zi-Hua Jiang
Structural analogues of diosgenyl saponins: synthesis and anticancer activity.
Bioorganic & medicinal chemistry 2009;17(22):7670-9.
2009: Nikhil Raghuram; Gustavo Carrero; John Th'ng; Michael Hendzel
Molecular dynamics of histone H1.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):189-206.
2008: Matthew J Kaskiw; Mary Lynn Tassotto; John Th'ng; Zi-Hua Jiang
Synthesis and cytotoxic activity of diosgenyl saponin analogues.
Bioorganic & medicinal chemistry 2008;16(6):3209-17.
2007: Christina Richard; Wilhelmina C M Duivenvoorden; Denis Bourbeau; B Massie; Wilson Roa; Jonathan Yau; John Th'ng
Sensitivity of 5-fluorouracil-resistant cancer cells to adenovirus suicide gene therapy.
Cancer gene therapy 2007;14(1):57-65.
2006: Natalie T Rundle; Jim Nelson; Mark R Flory; Jomon Joseph; John Th'ng; Ruedi Aebersold; Mary Dasso; Raymond J Andersen; Michel Roberge
An ent-kaurene that inhibits mitotic chromosome movement and binds the kinetochore protein ran-binding protein 2.
ACS chemical biology 2006;1(7):443-50.
2006: Christina Richard; Jonathan Yau; John Th'ng; Wilhelmina C M Duivenvoorden
Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents.
Clinical & experimental metastasis 2006;23(5-6):249-58.
2005: Alexey V Sorokin; Anastasia A Selyutina; Maxim A Skabkin; Sergey G Guryanov; Igor V Nazimov; Christina Richard; John Th'ng; Jonathan Yau; Poul H B Sorensen; Lev P Ovchinnikov; Valentina Evdokimova
Proteasome-mediated cleavage of the Y-box-binding protein 1 is linked to DNA-damage stress response.
The EMBO journal 2005;24(20):3602-12.
2005: John Th'ng; Rohyun Sung; Ming Ye; Michael Hendzel
H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain.
The Journal of biological chemistry 2005;280(30):27809-14.
2005: Christina Richard; Donald Matthews; Wilhelmina C M Duivenvoorden; Jonathan Yau; Paul S Wright; John Th'ng
Flavopiridol sensitivity of cancer cells isolated from ascites and pleural fluids.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(9):3523-9.
2004: Kozo Ajiro; John Th'ng; Jonathan Yau; Yoshimi Nishi
Isolation and characterization of mammalian cells that are undergoing apoptosis by a bovine serum albumin density gradient.
Analytical biochemistry 2004;332(2):226-33.
2004: Michael Hendzel; Melody A Lever; Ellen Crawford; John Th'ng
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
The Journal of biological chemistry 2004;279(19):20028-34.
2004: Nicolas Servant; Daniela Marcantonio; John Th'ng; Lorraine E Chalifour
TBP-associated factor 1 overexpression induces tolerance to Doxorubicin in confluent H9c2 cells by an increase in cdk2 activity and cyclin E expression.
Molecular and cellular biochemistry 2004;259(1-2):71-81.
2004: Gustavo Carrero; Ellen Crawford; John Th'ng; Gerda de Vries; Michael Hendzel
Quantification of protein-protein and protein-DNA interactions in vivo, using fluorescence recovery after photobleaching.
Methods in enzymology 2004;375():415-42.
2003: Wilson Roa; Hua Chen; Dorcas Fulton; Sunil Gulavita; Andrew Shaw; John Th'ng; Maxine Farr-Jones; Ronald Moore; Kenneth C Petruk
X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
Clinical and investigative medicine. Médecine clinique et experimentale 2003;26(5):231-42.
2003: Michael W McBurney; Xiaofeng Yang; Karen Jardine; Melissa Bieman; John Th'ng; Madeleine Lemieux
The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells.
Molecular cancer research : MCR 2003;1(5):402-9.
2001: Anna Derjuga; C Richard; Milena Crosato; P S Wright; Lorraine E Chalifour; Joseph G Valdez; A Barraso; H A Crissman; W Nishioka; E Morton Bradbury; John Th'ng
Expression of p21Waf1/Cip1 and cyclin D1 is increased in butyrate-resistant HeLa cells.
The Journal of biological chemistry 2001;276(41):37815-20.
2000: Melody A Lever; John Th'ng; X Sun; Michael Hendzel
Rapid exchange of histone H1.1 on chromatin in living human cells.
Nature 2000;408(6814):873-6.
1999: Audrey H Wang; Nicholas Bertos; M Vezmar; Nadine Pelletier; M Crosato; Hong-Qiang Heng; John Th'ng; J Han; Xiang-Jiao Yang
HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.
Molecular and cellular biology 1999;19(11):7816-27.
1998: Michael Hendzel; W K Nishioka; Y Raymond; C David Allis; David P Bazett-Jones; John Th'ng
Chromatin condensation is not associated with apoptosis.
The Journal of biological chemistry 1998;273(38):24470-8.
1997: R A Swank; John Th'ng; XW Guo; Joseph G Valdez; E Morton Bradbury; LR Gurley
Four distinct cyclin-dependent kinases phosphorylate histone H1 at all of its growth-related phosphorylation sites.
Biochemistry 1997;36(45):13761-8.