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Deborah Thomas

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Theresa Liu-Dumlao; Susan O'Brien; Hagop Kantarjian; Deborah A Thomas; Farhad Ravandi
Philadelphia-positive acute lymphoblastic leukemia: current treatment options.
Khanh Vu; Michael Andreeff; Kristine Broglio; Naifa L Busaidy; Maria Cabanillas; Joe Ensor; Carmen P Escalante; Stefan Faderl; Hagop Kantarjian; Marina Konopleva; Victor Lavis; Susan O'Brien; Deborah A Thomas; Sai-Ching Jim Yeung
A randomized controlled trial of an intensive insulin regimen in patients with hyperglycemic acute lymphoblastic leukemia.
Srdan Verstovsek; Sherry Pierce; Ester Pungolino; Elisa Rumi; Deborah A Thomas; Gautam Borthakur; Domenica Caramazza; Mario Cazzola; Jorge E Cortes; Zeev Estrov; Elias Jabbour; Tapan Kadia; Hagop M Kantarjian; Enrica Morra; Francesco Passamonti
Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls.

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All Publications

2012: Theresa Liu-Dumlao; Susan O'Brien; Hagop Kantarjian; Deborah A Thomas; Farhad Ravandi
Philadelphia-positive acute lymphoblastic leukemia: current treatment options.
Current oncology reports 2012;14(5):387-94.
2012: Khanh Vu; Michael Andreeff; Kristine Broglio; Naifa L Busaidy; Maria Cabanillas; Joe Ensor; Carmen P Escalante; Stefan Faderl; Hagop Kantarjian; Marina Konopleva; Victor Lavis; Susan O'Brien; Deborah A Thomas; Sai-Ching Jim Yeung
A randomized controlled trial of an intensive insulin regimen in patients with hyperglycemic acute lymphoblastic leukemia.
Clinical lymphoma, myeloma & leukemia 2012;12(5):355-62.
2012: Srdan Verstovsek; Sherry Pierce; Ester Pungolino; Elisa Rumi; Deborah A Thomas; Gautam Borthakur; Domenica Caramazza; Mario Cazzola; Jorge E Cortes; Zeev Estrov; Elias Jabbour; Tapan Kadia; Hagop M Kantarjian; Enrica Morra; Francesco Passamonti
Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls.
Blood 2012;120(6):1202-9.
2012: Shalini Verma; Farhad Ravandi; Neelima Reddy; Deborah A Thomas; Carlos E Bueso-Ramos; Wesley O Greaves; Hagop Kantarjian; Rajyalakshmi Luthra; L Jeffrey Medeiros; Susan O'Brien; Keyur P Patel
Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay.
American journal of clinical pathology 2012;138(1):153-6.
2012: Deborah A Thomas
Inotuzumab: the most active single agent in acute lymphoblastic leukemia?
Clinical advances in hematology & oncology : H&O 2012;10(4):251-4.
2012: Maria Cabanillas; B Nebiyou Bekele; Eduardo Bruera; Maria C Foudray; Hagop Kantarjian; Gloria N Mattiuzzi; Michael E Rytting; Deborah A Thomas; Lianchun Xiao; Jorge E Cortes
Epoetin alpha decreases the number of erythrocyte transfusions in patients with acute lymphoblastic leukemia, lymphoblastic lymphoma, and Burkitt leukemia/lymphoma: results of a randomized clinical trial.
Cancer 2012;118(3):848-55.
2011: Sergej Konoplev; E Lin; L Jeffrey Medeiros; Deborah A Thomas; Michael Andreeff; Jan Burger; Jeffrey L Jorgensen; Hagop M Kantarjian; Marina Konopleva
Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia.
Cancer 2011;117(20):4689-95.
2011: Alessandra Ferrajoli; Michael J Keating; Susan O'Brien; Jorge Cortes; Deborah A Thomas
Experience with rituximab immunotherapy as an early intervention in patients with Rai stage 0 to II chronic lymphocytic leukemia.
Cancer 2011;117(14):3182-6.
2011: Elias Jabbour; Hagop Kantarjian; Farhad Ravandi; Guillermo Garcia-Manero; Zeev Estrov; Srdan Verstovsek; Susan O'Brien; Stefan Faderl; Deborah A Thomas; John J Wright; Jorge Cortes
A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome.
Cancer 2011;117(6):1236-44.
2011: Deborah A Thomas; Susan O'Brien; Stefan Faderl; John T Manning; Jorge Romaguera; Luis Fayad; Fredrick Hagemeister; Jeffrey Medeiros; Jorge Cortes; Hagop Kantarjian
Burkitt lymphoma and atypical Burkitt or Burkitt-like lymphoma: should these be treated as different diseases?
Current hematologic malignancy reports 2011;6(1):58-66.
2011: Bing Z Carter; Yi Hua Qiu; Nianxiang Zhang; Kevin R Coombes; Duncan H Mak; Deborah A Thomas; Farhad Ravandi; Hagop M Kantarjian; Erich Koller; Michael Andreeff; Steven M Kornblau
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.
Blood 2011;117(3):780-7.
2011: Juliana Benito; Ingrid Boehm; Gautam Borthakur; Carlos Bueso-Ramos; Dario Campana; Hernan Carol; Wendy Fang; Craig T Jordan; Hagop Kantarjian; Sergej Konoplev; Richard Lock; Hongbo Lu; Yuexi Shi; Elizabeth Shpall; Barbara Szymanska; Deborah A Thomas; William R Wilson; Patrick A Zweidler-McKay; Michael Andreeff; Marina Konopleva
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
PloS one 2011;6(8):e23108.
2010: Zhuang Zuo; Dan Jones; Hui Yao; Deborah A Thomas; Susan O'Brien; Farhad Ravandi; Hagop M Kantarjian; Lynne V Abruzzo; L Jeffrey Medeiros; Su S Chen; Rajyalakshmi Luthra
A pathway-based gene signature correlates with therapeutic response in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(11):1524-34.
2010: Deborah A Thomas; Susan O'Brien; Stefan Faderl; Guillermo Garcia-Manero; Alessandra Ferrajoli; William G Wierda; Farhad Ravandi; Srdan Verstovsek; Jeffrey L Jorgensen; Carlos E Bueso-Ramos; Michael Andreeff; Sherry Pierce; Rebecca Garris; Michael J Keating; Jorge Cortes; Hagop M Kantarjian
Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(24):3880-9.
2010: Tapan M Kadia; Hui Yang; Alessandra Ferrajoli; Sirisha Maddipotti; Claudia Schroeder; Timothy L Madden; Julianne L Holleran; Merrill J Egorin; Farhad Ravandi; Deborah A Thomas; Willie Newsome; Blanca Sanchez-Gonzalez; James Zwiebel; Igor Espinoza-Delgado; Hagop M Kantarjian; Guillermo Garcia-Manero
A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.
British journal of haematology 2010;150(1):72-82.
2010: Deborah A Thomas
Rituximab as therapy for acute lymphoblastic leukemia.
Clinical advances in hematology & oncology : H&O 2010;8(3):168-71.
2010: Fabio P S Santos; Hagop M Kantarjian; Nitin Jain; Taghi Manshouri; Deborah A Thomas; Guillermo Garcia-Manero; Debra Kennedy; Zeev Estrov; Jorge Cortes; Srdan Verstovsek
Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
Blood 2010;115(6):1131-6.
2009: Deborah A Thomas; Hagop M Kantarjian; Wendy Stock; Leonard T Heffner; Stefan Faderl; Guillermo Garcia-Manero; Alessandra Ferrajoli; William G Wierda; Sherry Pierce; Biao Lu; Steven R Deitcher; Susan O'Brien
Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia.
Cancer 2009;115(23):5490-8.
2009: Constantine S Tam; Andrew Lamb; Jorge Cortes; Alice Lynn; Sherry Pierce; Lingsha Zhou; Michael J Keating; Deborah A Thomas; Srdan Verstovsek
Dynamic model for predicting death within 12 months in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(33):5587-93.
2009: Tariq Muzzafar; L Jeffrey Medeiros; Sa A Wang; Archana Brahmandam; Deborah A Thomas; Jeffrey L Jorgensen
Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia: utility in detection of minimal residual disease by flow cytometry.
American journal of clinical pathology 2009;132(5):692-8.
2009: Deborah A Thomas; Susan O'Brien; Hagop M Kantarjian
Monoclonal antibody therapy with rituximab for acute lymphoblastic leukemia.
Hematology/oncology clinics of North America 2009;23(5):949-71, v.
2009: Deborah A Thomas; Farhad Ravandi; Michael Keating; Hagop M Kantarjian
Importance of minimal residual disease in hairy cell leukemia: monoclonal antibodies as a therapeutic strategy.
Leukemia & lymphoma 2009;50 Suppl 1():27-31.
2009: Constantine S Tam; Lynne V Abruzzo; Katherine I Lin; Jorge Cortes; Alice Lynn; Michael J Keating; Deborah A Thomas; Sherry Pierce; Andrew Lamb; Srdan Verstovsek
The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course.
Blood 2009;113(18):4171-8.
2008: Susan O'Brien; Deborah A Thomas; Farhad Ravandi; Stefan Faderl; Sherry Pierce; Andrew Lamb
Results of the hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen in elderly patients with acute lymphocytic leukemia.
Cancer 2008;113(8):2097-101.
2008: Constantine S Tam; Roberto M Nussenzveig; Uday Popat; Carlos E Bueso-Ramos; Deborah A Thomas; Jorge A Cortes; Richard E Champlin; Stefan E Ciurea; Taghi Manshouri; Sherry M Pierce; Hagop M Kantarjian; Srdan Verstovsek
The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms.
Blood 2008;112(5):1628-37.
2008: Stefan Faderl; Farhad Ravandi; Xuelin Huang; Guillermo Garcia-Manero; Alessandra Ferrajoli; Zeev Estrov; Gautam Borthakur; Srdan Verstovsek; Deborah A Thomas; Monica Kwari; Hagop M Kantarjian
A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome.
Blood 2008;112(5):1638-45.
2008: Constantine S Tam; Susan O'Brien; William G Wierda; Andrew Lamb; Sijin Wen; Kim-Anh Do; Deborah A Thomas; Jorge Cortes; Susan Lerner; Michael J Keating
Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia.
Blood 2008;112(4):975-80.
2007: Deborah A Thomas; Susan O'Brien; Jorge Cortes; Andrew Lamb
New approaches to the management of Philadelphia-chromosome-positive acute lymphocytic leukemia.
Current hematologic malignancy reports 2007;2(3):183-9.
2007: Elias Jabbour; Susan O'Brien; Andrew Lamb; Guillermo Garcia-Manero; Alessandra Ferrajoli; Farhad Ravandi; Maria Cabanillas; Deborah A Thomas
Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia.
Blood 2007;109(8):3214-8.
2007: Ahmed Aribi; Hagop M Kantarjian; Elihu H Estey; Charles Koller; Deborah A Thomas; Steven M Kornblau; Stefan Faderl; Nakia M Laddie; Guillermo Garcia-Manero; Jorge E Cortes
Combination therapy with arsenic trioxide, all-trans retinoic acid, and gemtuzumab ozogamicin in recurrent acute promyelocytic leukemia.
Cancer 2007;109(7):1355-9.
2007: Gautam Borthakur; Susan O'Brien; William G Wierda; Deborah A Thomas; Jorge E Cortes; Francis Giles; Hagop M Kantarjian; Susan Lerner; Michael J Keating
Immune anaemias in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab--incidence and predictors.
British journal of haematology 2007;136(6):800-5.
2006: Deborah A Thomas; Farhad Ravandi; Andrew Lamb
Monoclonal antibody therapy for hairy cell leukemia.
Hematology/oncology clinics of North America 2006;20(5):1125-36.
2006: Farhad Ravandi; Jeffrey L Jorgensen; Susan M O'Brien; Srdan Verstovsek; Charles Koller; Stefan Faderl; Francis Giles; Alessandra Ferrajoli; William G Wierda; Shirley Odinga; Xuelin Huang; Deborah A Thomas; Emil J Freireich; Dan Jones; Michael J Keating; Hagop M Kantarjian
Eradication of minimal residual disease in hairy cell leukemia.
Blood 2006;107(12):4658-62.
2006: Deborah A Thomas; Francis Giles; Maher Albitar; Jorge E Cortes; Srdan Verstovsek; Stefan Faderl; Susan M O'Brien; Guillermo Garcia-Manero; Michael J Keating; Sherry Pierce; Jerome B Zeldis; Hagop M Kantarjian
Thalidomide therapy for myelofibrosis with myeloid metaplasia.
Cancer 2006;106(9):1974-84.
2006: Deborah A Thomas; Stefan Faderl; Susan O'Brien; Carlos E Bueso-Ramos; Jorge Cortes; Guillermo Garcia-Manero; Francis Giles; Srdan Verstovsek; William G Wierda; Sherry A Pierce; Jianqin Shan; Mark Brandt; Fredrick B Hagemeister; Michael J Keating; Fernando Cabanillas; Andrew Lamb
Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia.
Cancer 2006;106(7):1569-80.
2006: Hui-Ti See; Deborah A Thomas; Carlos E Bueso-Ramos; John Kavanagh
Secondary leukemia after treatment with paclitaxel and carboplatin in a patient with recurrent ovarian cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2006;16 Suppl 1():236-40.
2006: Deborah A Thomas; Andreas H Sarris; Jorge Cortes; Stefan Faderl; Susan O'Brien; Francis Giles; Guillermo Garcia-Manero; Maria A Rodriguez; Fernando Cabanillas; Andrew Lamb
Phase II study of sphingosomal vincristine in patients with recurrent or refractory adult acute lymphocytic leukemia.
Cancer 2006;106(1):120-7.
2005: Stefan Faderl; Kim-Anh Do; Marcella M Johnson; Michael Keating; Susan O'Brien; Iman Jilani; Alessandra Ferrajoli; Farhad Ravandi-Kashani; Christine Aguilar; Amanda Dey; Deborah A Thomas; Francis Giles; Hagop M Kantarjian; Maher Albitar
Angiogenic factors may have a different prognostic role in adult acute lymphoblastic leukemia.
Blood 2005;106(13):4303-7.
2005: Apostolia-Maria Tsimberidou; Francis Giles; Issa Khouri; Carlos E Bueso-Ramos; Susan R Pilat; Deborah A Thomas; Jorge Cortes; Razelle Kurzrock
Low-dose interleukin-11 in patients with bone marrow failure: update of the M. D. Anderson Cancer Center experience.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(1):139-45.
2005: Bryan T. J. Hennessy; Deborah A Thomas; Francis Giles; Andrew Lamb; Srdan Verstovsek
New approaches in the treatment of myelofibrosis.
Cancer 2005;103(1):32-43.
2004: Deborah A Thomas; Susan O'Brien; Jorge Cortes; Francis Giles; Stefan Faderl; Srdan Verstovsek; Alessandra Ferrajoli; Charles Koller; Miloslav Beran; Sherry Pierce; Chul Ha; Fernando Cabanillas; Michael J Keating; Andrew Lamb
Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma.
Blood 2004;104(6):1624-30.
2004: Deborah A Thomas; Stefan Faderl; Jorge Cortes; Susan O'Brien; Francis Giles; Steven M Kornblau; Guillermo Garcia-Manero; Michael J Keating; Michael Andreeff; Sima Jeha; Miloslav Beran; Srdan Verstovsek; Sherry Pierce; Laurie Letvak; August Salvado; Richard Champlin; Moshe Talpaz; Andrew Lamb
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.
Blood 2004;103(12):4396-407.
2004: Razelle Kurzrock; Maher Albitar; Jorge E Cortes; Elihu H Estey; Stefan Faderl; Guillermo Garcia-Manero; Deborah A Thomas; Francis Giles; Mary Ellen Ryback; Alain Thibault; P De Porre; Hagop M Kantarjian
Phase II study of R115777, a farnesyl transferase inhibitor, in myelodysplastic syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(7):1287-92.
2004: Francis Giles; Martin S Tallman; Guillermo Garcia-Manero; Jorge E Cortes; Deborah A Thomas; William G Wierda; Srdan Verstovsek; Marta Hamilton; Emma Barrett; Maher Albitar; Hagop M Kantarjian
Phase I and pharmacokinetic study of a low-clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase 1 inhibitor, in patients with advanced leukemia.
Cancer 2004;100(7):1449-58.
2004: Mary Ann Weiser; Maria Cabanillas; Marina Konopleva; Deborah A Thomas; Sherry A Pierce; Carmen P Escalante; Hagop M Kantarjian; Susan M O'Brien
Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen.
Cancer 2004;100(6):1179-85.
2003: Susan M O'Brien; Hagop M Kantarjian; Deborah A Thomas; Jorge Cortes; Francis Giles; William G Wierda; Charles Koller; Alessandra Ferrajoli; Mary L Browning; Susan Lerner; Maher Albitar; Michael J Keating
Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia.
Cancer 2003;98(12):2657-63.
2003: Apostolia-Maria Tsimberidou; Elihu Estey; Jorge E Cortes; Guillermo Garcia-Manero; Stefan Faderl; Srdan Verstovsek; Deborah A Thomas; Alessandra Ferrajoli; Michael J Keating; Susan O'Brien; Hagop M Kantarjian; Francis Giles
Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia.
Cancer chemotherapy and pharmacology 2003;52(6):449-52.
2003: Francis Giles; Paula M Fracasso; Hagop M Kantarjian; Jorge E Cortes; Randy A Brown; Srdan Verstovsek; Yesid Alvarado; Deborah A Thomas; Stefan Faderl; Guillermo Garcia-Manero; Lisa P Wright; Tom Samson; Ann Cahill; Paula Lambert; William Plunkett; Mario Sznol; John F DiPersio; Varsha Gandhi
Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia.
Leukemia research 2003;27(12):1077-83.
2003: Deborah A Thomas; Susan O'Brien; Carlos E Bueso-Ramos; Stefan Faderl; Michael J Keating; Francis Giles; Jorge Cortes; Hagop M Kantarjian
Rituximab in relapsed or refractory hairy cell leukemia.
Blood 2003;102(12):3906-11.
2003: Iman Jilani; Susan O'Brien; Taghi Manshuri; Deborah A Thomas; Vilmos A Thomazy; Maha Imam; Sana Naeem; Srdan Verstovsek; Andrew Lamb; Francis Giles; Michael Keating; Maher Albitar
Transient down-modulation of CD20 by rituximab in patients with chronic lymphocytic leukemia.
Blood 2003;102(10):3514-20.
2003: Miloslav Beran; Susan O'Brien; Deborah A Thomas; Hai T Tran; Jorge E Cortes-Franco; Francis Giles; Elihu Estey; Hagop M Kantarjian
Phase I study of oral topotecan in hematological malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(11):4084-91.
2003: Hesham M Amin; Iman Jilani; Elihu H Estey; Michael J Keating; Amanda L Dey; Taghi Manshouri; Hagop M Kantarjian; Zeev Estrov; Jorge E Cortes; Deborah A Thomas; Francis Giles; Maher Albitar
Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome.
Blood 2003;102(5):1866-8.
2003: Alessandra Ferrajoli; Susan M O'Brien; Jorge E Cortes; Francis Giles; Deborah A Thomas; Stefan Faderl; Razelle Kurzrock; Susan Lerner; Dimitrios P Kontoyiannis; Michael J Keating
Phase II study of alemtuzumab in chronic lymphoproliferative disorders.
Cancer 2003;98(4):773-8.
2003: Jorge E Cortes; Moshe Talpaz; Francis Giles; Susan O'Brien; Mary Beth Rios; Jianqin Shan; Guillermo Garcia-Manero; Stefan Faderl; Deborah A Thomas; William G Wierda; Alessandra Ferrajoli; Sima Jeha; Hagop M Kantarjian
Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy.
Blood 2003;101(10):3794-800.
2003: Francis Giles; Hagop M Kantarjian; Jorge E Cortes; Guillermo Garcia-Manero; Srdan Verstovsek; Stefan Faderl; Deborah A Thomas; Alessandra Ferrajoli; Susan O'Brien; J Kyle Wathen; Lian-Chun Xiao; Donald A Berry; Elihu H Estey
Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(9):1722-7.
2003: Stefan Faderl; Deborah A Thomas; Susan O'Brien; Guillermo Garcia-Manero; Hagop M Kantarjian; Francis Giles; Charles Koller; Alessandra Ferrajoli; Srdan Verstovsek; Barbara Pro; Michael Andreeff; Miloslav Beran; Jorge Cortes; William G Wierda; Ngoc Tran; Michael J Keating
Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies.
Blood 2003;101(9):3413-5.
2003: Francis Giles; Maureen A Cooper; Lewis Silverman; Judith E Karp; Jeffrey E Lancet; Maurizio Zangari; Paul J Shami; Khuda Dad Khan; Alison L Hannah; Julie M Cherrington; Deborah A Thomas; Guillermo Garcia-Manero; Maher Albitar; Hagop M Kantarjian; Alison T Stopeck
Phase II study of SU5416--a small-molecule, vascular endothelial growth factor tyrosine-kinase receptor inhibitor--in patients with refractory myeloproliferative diseases.
Cancer 2003;97(8):1920-8.
2003: Apostolia-Maria Tsimberidou; Hagop M Kantarjian; Jorge Cortes; Deborah A Thomas; Stefan Faderl; Guillermo Garcia-Manero; Srdan Verstovsek; Alessandra Ferrajoli; William G Wierda; Yesid Alvarado; Susan M O'Brien; Maher Albitar; Michael J Keating; Francis Giles
Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients with Richter syndrome or fludarabine-refractory chronic lymphocytic leukemia.
Cancer 2003;97(7):1711-20.
2003: Francis Giles; Stefan Faderl; Deborah A Thomas; Jorge E Cortes; Guillermo Garcia-Manero; Dan Douer; Alexandra M Levine; Charles Koller; Sima Jeha; Susan M O'Brien; Elihu H Estey; Hagop M Kantarjian
Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(6):1050-6.
2003: Dawn E Colburn; Deborah A Thomas; Francis Giles
Phase II study of single agent paclitaxel in adult patients with relapsed acute lymphocytic leukemia.
Investigational new drugs 2003;21(1):109-11.
2002: Deborah A Thomas; Jorge Cortes; Hagop M Kantarjian
New agents in the treatment of acute lymphocytic leukaemia.
Best practice & research. Clinical haematology 2002;15(4):771-90.
2002: Francis Giles; Hagop M Kantarjian; B Nebiyou Bekele; Jorge E Cortes; Stefan Faderl; Deborah A Thomas; Taghi Manshouri; Anna Rogers; Michael J Keating; Moshe Talpaz; Susan O'Brien; Maher Albitar
Bone marrow cyclooxygenase-2 levels are elevated in chronic-phase chronic myeloid leukaemia and are associated with reduced survival.
British journal of haematology 2002;119(1):38-45.
2002: Hagop M Kantarjian; Susan O'Brien; Jorge E Cortes; Sergio Giralt; Mary Beth Rios; Jianqin Shan; Francis Giles; Deborah A Thomas; Stefan Faderl; Marcos De Lima; Guillermo Garcia-Manero; Richard Champlin; Ralph B Arlinghaus; Moshe Talpaz
Imatinib mesylate therapy for relapse after allogeneic stem cell transplantation for chronic myelogenous leukemia.
Blood 2002;100(5):1590-5.
2002: Alessandra Ferrajoli; Michael J Keating; Taghi Manshouri; Francis Giles; Amanda Dey; Zeev Estrov; Charles Koller; Razelle Kurzrock; Deborah A Thomas; Stefan Faderl; Susan Lerner; Susan O'Brien; Maher Albitar
The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia.
Blood 2002;100(4):1215-9.
2002: Hagop M Kantarjian; Moshe Talpaz; Susan O'Brien; Terry L Smith; Francis Giles; Stefan Faderl; Deborah A Thomas; Guillermo Garcia-Manero; Jean-Pierre J Issa; Michael Andreeff; Steven M Kornblau; Charles Koller; Miloslav Beran; Michael Keating; Mary Beth Rios; Jianqin Shan; Debra Resta; Renaud Capdeville; Kimberly Hayes; Maher Albitar; Emil J Freireich; Jorge E Cortes
Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2177-87.
2002: Hagop M Kantarjian; Susan O'Brien; Jorge E Cortes; Terry L Smith; Mary Beth Rios; Jianqin Shan; Ying Yang; Francis Giles; Deborah A Thomas; Stefan Faderl; Guillermo Garcia-Manero; Sima Jeha; William G Wierda; Jean-Pierre J Issa; Steven M Kornblau; Michael Keating; Debra Resta; Renaud Capdeville; Moshe Talpaz
Treatment of philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2167-76.
2002: Francis Giles; Jorge E Cortes; Deborah A Thomas; Guillermo Garcia-Manero; Stefan Faderl; Sima Jeha; Robert L De Jager; Hagop M Kantarjian
Phase I and pharmacokinetic study of DX-8951f (exatecan mesylate), a hexacyclic camptothecin, on a daily-times-five schedule in patients with advanced leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2134-41.
2002: Elihu H Estey; Peter F Thall; Francis Giles; Xue-Mei Wang; Jorge E Cortes; Miloslav Beran; Sherry A Pierce; Deborah A Thomas; Hagop M Kantarjian
Gemtuzumab ozogamicin with or without interleukin 11 in patients 65 years of age or older with untreated acute myeloid leukemia and high-risk myelodysplastic syndrome: comparison with idarubicin plus continuous-infusion, high-dose cytosine arabinoside.
Blood 2002;99(12):4343-9.
2002: Stefan Faderl; Guillermo Garcia-Manero; Deborah A Thomas; Hagop M Kantarjian
Philadelphia chromosome-positive acute lymphoblastic leukemia- current concepts and future perspectives.
Reviews in clinical and experimental hematology 2002;6(2):142-60; discussion 200-2.
2002: Bouthaina S Dabaja; Chul Ha; Deborah A Thomas; Richard B Wilder; Ramesh Gopal; Jorge Cortes; Carlos E Bueso-Ramos; Mark A Hess; James D Cox; Hagop M Kantarjian
The role of local radiation therapy for mediastinal disease in adults with T-cell lymphoblastic lymphoma.
Cancer 2002;94(10):2738-44.
2002: Hagop M Kantarjian; Jorge Cortes; Susan O'Brien; Francis Giles; Maher Albitar; Mary Beth Rios; Jianqin Shan; Stefan Faderl; Guillermo Garcia-Manero; Deborah A Thomas; Debra Resta; Moshe Talpaz
Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase.
Blood 2002;99(10):3547-53.
2002: Francis Giles; Guillermo Garcia-Manero; Jorge E Cortes; Sharyn D Baker; Carole B Miller; Susan M O'Brien; Deborah A Thomas; Michael Andreeff; Carol Bivins; Jacques Jolivet; Hagop M Kantarjian
Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(3):656-64.
2002: Mary Ann Weiser; Susan O'Brien; Deborah A Thomas; Sherry A Pierce; Tony P Lam; Hagop M Kantarjian
Comparison of two different schedules of granulocyte-colony-stimulating factor during treatment for acute lymphocytic leukemia with a hyper-CVAD (cyclophosphamide, doxorubicin, vincristine, and dexamethasone) regimen.
Cancer 2002;94(2):285-91.
2001: Razelle Kurzrock; Jorge Cortes; Deborah A Thomas; Sima Jeha; Susan R Pilat; Moshe Talpaz
Pilot study of low-dose interleukin-11 in patients with bone marrow failure.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(21):4165-72.
2001: Miloslav Beran; Yu Shen; Andrew Lamb; Susan O'Brien; Charles Koller; Francis Giles; Jorge Cortes; Deborah A Thomas; Stefan Faderl; Simona Despa; Elihu H Estey
High-dose chemotherapy in high-risk myelodysplastic syndrome: covariate-adjusted comparison of five regimens.
Cancer 2001;92(8):1999-2015.
2001: Francis Giles; Hagop M Kantarjian; Steven M Kornblau; Deborah A Thomas; Guillermo Garcia-Manero; Tracey A Waddelow; Cynthia L David; Alexandria Phan; Dawn E Colburn; Asif Rashid; Elihu H Estey
Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation.
Cancer 2001;92(2):406-13.
2001: Bouthaina S Dabaja; Susan M O'Brien; Hagop M Kantarjian; Jorge E Cortes; Deborah A Thomas; Maher Albitar; E S Schlette; Stefan Faderl; Andreas H Sarris; Michael J Keating; Francis Giles
Fractionated cyclophosphamide, vincristine, liposomal daunorubicin (daunoXome), and dexamethasone (hyperCVXD) regimen in Richter's syndrome.
Leukemia & lymphoma 2001;42(3):329-37.
2001: Susan M O'Brien; Andrew Lamb; Deborah A Thomas; Francis Giles; Emil J Freireich; Jorge Cortes; Susan Lerner; Michael J Keating
Rituximab dose-escalation trial in chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(8):2165-70.
2001: Deborah A Thomas; Hagop M Kantarjian
Lymphoblastic lymphoma.
Hematology/oncology clinics of North America 2001;15(1):51-95, vi.
2001: Guillermo Garcia-Manero; Deborah A Thomas
Salvage therapy for refractory or relapsed acute lymphocytic leukemia.
Hematology/oncology clinics of North America 2001;15(1):163-205.
2001: Francis Giles; Jorge E Cortes; Sharyn D Baker; Deborah A Thomas; Susan O'Brien; Terry L Smith; Miloslav Beran; Carol Bivins; J Jolivet; Hagop M Kantarjian
Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(3):762-71.
2000: Deborah A Thomas; Hagop M Kantarjian
Current role of thalidomide in cancer treatment.
Current opinion in oncology 2000;12(6):564-73.
2000: Stefan Faderl; Hagop M Kantarjian; Elihu Estey; Taghi Manshouri; C Y Chan; A Rahman Elsaied; Steven M Kornblau; Jorge Cortes; Deborah A Thomas; Sherry Pierce; Michael J Keating; Zeev Estrov; Maher Albitar
The prognostic significance of p16(INK4a)/p14(ARF) locus deletion and MDM-2 protein expression in adult acute myelogenous leukemia.
Cancer 2000;89(9):1976-82.
2000: Stefan Faderl; Hagop M Kantarjian; Deborah A Thomas; Jorge Cortes; Francis Giles; Sherry Pierce; Maher Albitar; Zeev Estrov
Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia.
Leukemia & lymphoma 2000;36(3-4):263-73.
1999: Deborah A Thomas; Andrew Lamb; Terry L Smith; Charles Koller; Jorge Cortes; Susan O'Brien; Francis Giles; James L Gajewski; Sherry Pierce; Michael J Keating
Primary refractory and relapsed adult acute lymphoblastic leukemia: characteristics, treatment results, and prognosis with salvage therapy.
Cancer 1999;86(7):1216-30.
1999: Francis Giles; Hagop M Kantarjian; Jorge Cortes; Deborah A Thomas; Moshe Talpaz; Taghi Manshouri; Maher Albitar
Multidrug resistance protein expression in chronic myeloid leukemia: associations and significance.
Cancer 1999;86(5):805-13.
1999: Deborah A Thomas; Jorge Cortes; Susan O'Brien; Sherry Pierce; Stefan Faderl; Maher Albitar; Fredrick B Hagemeister; Fernando Cabanillas; S Murphy; Michael J Keating; Andrew Lamb
Hyper-CVAD program in Burkitt's-type adult acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(8):2461-70.