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Nikhil Thomas

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Concepts & Ideas

Living Beings

Anatomy

Flagellum

Physiology

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Publications

TOP 3
Victor Antonio Garcia Angulo; Wanyin Deng; Nikhil A Thomas; B Brett Finlay; José Luis Puente
Regulation of expression and secretion of NleH, a new non-locus of enterocyte effacement-encoded effector in Citrobacter rodentium.
Nikhil A Thomas; Wanyin Deng; Noel Baker; José Luis Puente; B Brett Finlay
Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli.
Jinoh Kim; Ajitha Thanabalasuriar; Tessa Chaworth-Musters; J Christopher Fromme; Elizabeth A Frey; Paula Lario; Pavel Metalnikov; Keyrillos Rizg; Nikhil A Thomas; Sau Fung Lee; Elizabeth L Hartland; Philip R Hardwidge; Tony Pawson; Natalie C J Strynadka; B Brett Finlay; Randy Schekman; Samantha Gruenheid
The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function.

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All Publications

2008: Victor Antonio Garcia Angulo; Wanyin Deng; Nikhil A Thomas; B Brett Finlay; José Luis Puente
Regulation of expression and secretion of NleH, a new non-locus of enterocyte effacement-encoded effector in Citrobacter rodentium.
Journal of bacteriology 2008;190(7):2388-99.
2007: Nikhil A Thomas; Wanyin Deng; Noel Baker; José Luis Puente; B Brett Finlay
Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli.
The Journal of biological chemistry 2007;282(40):29634-45.
2007: Jinoh Kim; Ajitha Thanabalasuriar; Tessa Chaworth-Musters; J Christopher Fromme; Elizabeth A Frey; Paula Lario; Pavel Metalnikov; Keyrillos Rizg; Nikhil A Thomas; Sau Fung Lee; Elizabeth L Hartland; Philip R Hardwidge; Tony Pawson; Natalie C J Strynadka; B Brett Finlay; Randy Schekman; Samantha Gruenheid
The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function.
Cell host & microbe 2007;2(3):160-71.
2005: Nikhil A Thomas; Wanyin Deng; José Luis Puente; Elizabeth A Frey; Calvin K Yip; Natalie C J Strynadka; B Brett Finlay
CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli.
Molecular microbiology 2005;57(6):1762-79.
2005: Calvin K Yip; Tyler G Kimbrough; Heather B Felise; Marija Vuckovic; Nikhil A Thomas; Richard A Pfuetzner; Elizabeth A Frey; B Brett Finlay; Samuel I Miller; Natalie C J Strynadka
Structural characterization of the molecular platform for type III secretion system assembly.
Nature 2005;435(7042):702-7.
2004: Nikhil A Thomas; B Brett Finlay
Pathogens: bacterial needles ruled to length and specificity.
Current biology : CB 2004;14(5):R192-4.
2004: Samantha Gruenheid; Inna Sekirov; Nikhil A Thomas; Wanyin Deng; Paul O'Donnell; David Goode; Yuling Li; Elizabeth A Frey; Nat F Brown; Pavel Metalnikov; Tony Pawson; Keith Ashman; B Brett Finlay
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.
Molecular microbiology 2004;51(5):1233-49.
2003: Nikhil A Thomas; B Brett Finlay
Establishing order for type III secretion substrates--a hierarchical process.
Trends in microbiology 2003;11(8):398-403.
2003: Annick Gauthier; Nikhil A Thomas; B Brett Finlay
Bacterial injection machines.
The Journal of biological chemistry 2003;278(28):25273-6.
2002: Nikhil A Thomas; Steffen Mueller; Albrecht Klein; Ken F Jarrell
Mutants in flaI and flaJ of the archaeon Methanococcus voltae are deficient in flagellum assembly.
Molecular microbiology 2002;46(3):879-87.
2001: Nikhil A Thomas; Ken F Jarrell
Characterization of flagellum gene families of methanogenic archaea and localization of novel flagellum accessory proteins.
Journal of bacteriology 2001;183(24):7154-64.
2001: Nikhil A Thomas; C T Pawson; Ken F Jarrell
Insertional inactivation of the flaH gene in the archaeon Methanococcus voltae results in non-flagellated cells.
Molecular genetics and genomics : MGG 2001;265(4):596-603.
2001: Nikhil A Thomas; E D Chao; Ken F Jarrell
Identification of amino acids in the leader peptide of Methanococcus voltae preflagellin that are important in posttranslational processing.
Archives of microbiology 2001;175(4):263-9.
2001: Nikhil A Thomas; Sonia L Bardy; Ken F Jarrell
The archaeal flagellum: a different kind of prokaryotic motility structure.
FEMS microbiology reviews 2001;25(2):147-74.
1999: Ken F Jarrell; J D Correia; Nikhil A Thomas
Is the processing and translocation system used by flagellins also used by membrane-anchored secretory proteins in archaea?
Molecular microbiology 1999;34(2):395-8.
1997: Ken F Jarrell; T Vydykhan; P Lee; M D Agnew; Nikhil A Thomas
Isolation and characterization of bacteriophage BCJA1, a novel temperate bacteriophage active against the alkaliphilic bacterium, Bacillus clarkii.
Extremophiles : life under extreme conditions 1997;1(4):199-206.
1996: David M Faguy; D P Bayley; Alla S Kostyukova; Nikhil A Thomas; Ken F Jarrell
Isolation and characterization of flagella and flagellin proteins from the Thermoacidophilic archaea Thermoplasma volcanium and Sulfolobus shibatae.
Journal of bacteriology 1996;178(3):902-5.