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Laszlo Boros

Research Profile

Physiology

Chemicals & Drugs

Disorders

Anatomy

Tumor Cells, Cultured

Living Beings

Mouse
Rats

Co-author Network

Publications

TOP 3
Virender K Rehan; Ying Wang; Sharon Sugano; Jamie Santos; Sanjay Patel; Reiko Sakurai; Laszlo G Boros; Laszlo W Boros; W-P Lee; John S Torday
In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism.
Laszlo G Boros; Megan R Lerner; Daniel L Morgan; Stephanie L Taylor; Brenda J Smith; Russell G Postier; Daniel J Brackett
[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats.
Pedro Vizan; Laszlo G Boros; Agnès Figueras; Gabriel Capella; Bafalluy Mangues; Sara Bassilian; Shu Lim; W N Paul Lee; Marta Cascante
K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts.

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All Publications

2007: Virender K Rehan; Ying Wang; Sharon Sugano; Jamie Santos; Sanjay Patel; Reiko Sakurai; Laszlo G Boros; Laszlo W Boros; W-P Lee; John S Torday
In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism.
American journal of physiology. Lung cellular and molecular physiology 2007;292(1):L323-33.
2005: Laszlo G Boros; Megan R Lerner; Daniel L Morgan; Stephanie L Taylor; Brenda J Smith; Russell G Postier; Daniel J Brackett
[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats.
Pancreas 2005;31(4):337-43.
2005: Pedro Vizan; Laszlo G Boros; Agnès Figueras; Gabriel Capella; Bafalluy Mangues; Sara Bassilian; Shu Lim; W N Paul Lee; Marta Cascante
K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts.
Cancer research 2005;65(13):5512-5.
2005: George G Harrigan; Daniel J Brackett; Laszlo G Boros
Medicinal chemistry, metabolic profiling and drug target discovery: a role for metabolic profiling in reverse pharmacology and chemical genetics.
Mini reviews in medicinal chemistry 2005;5(1):13-20.
2004: W N Paul Lee; P Guo; Shu Lim; Sara Bassilian; S T Lee; Joan Boren; Marta Cascante; Vay Liang W Go; Laszlo G Boros
Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment.
British journal of cancer 2004;91(12):2094-100.
2004: Silvia Marin; W N Paul Lee; Sara Bassilian; Shu Lim; Laszlo G Boros; Josep J Centelles; Josep Maria FernAndez-Novell; Joan J Guinovart; Marta Cascante
Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose.
The Biochemical journal 2004;381(Pt 1):287-94.
2003: Laszlo G Boros; Daniel J Brackett; George G Harrigan
Metabolic biomarker and kinase drug target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP).
Current cancer drug targets 2003;3(6):445-53.
2003: Silvia Marin; Kelly Chiang; Sara Bassilian; W N Paul Lee; Laszlo G Boros; Josep M Fernández-Novell; Josep J Centelles; Antonio Medrano; Joan Enric Rodriguez-Gil; Marta Cascante
Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization.
FEBS letters 2003;554(3):342-6.
2003: Laszlo G Boros; Mara P Steinkamp; Judith C Fleming; W N Paul Lee; Marta Cascante; Ellis J Neufeld
Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).
Blood 2003;102(10):3556-61.
2003: Joan Boren; W N Paul Lee; Sara Bassilian; Josep J Centelles; Shu Lim; Sayed Ahmed; Laszlo G Boros; Marta Cascante
The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation.
The Journal of biological chemistry 2003;278(31):28395-402.
2002: Begoña Comin-Anduix; Laszlo G Boros; Silvia Marin; Joan Boren; Carles Callol-Massot; Josep J Centelles; Josep Lluís Torres; Neus Agell; Sara Bassilian; Marta Cascante
Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells.
The Journal of biological chemistry 2002;277(48):46408-14.
2002: Laszlo G Boros; John S Torday; Wai-Nang Paul Lee; Virender K Rehan
Oxygen-induced metabolic changes and transdifferentiation in immature fetal rat lung lipofibroblasts.
Molecular genetics and metabolism 2002;77(3):230-6.
2002: Laszlo G Boros; W N Paul Lee; Marta Cascante
Imatinib and chronic-phase leukemias.
The New England journal of medicine 2002;347(1):67-8.
2002: Laszlo G Boros; Marta Cascante; W N Paul Lee
Metabolic profiling of cell growth and death in cancer: applications in drug discovery.
Drug discovery today 2002;7(6):364-72.
2002: Marta Cascante; Laszlo G Boros; Begoña Comin-Anduix; Pedro de Atauri; Josep J Centelles; Paul W-N Lee
Metabolic control analysis in drug discovery and disease.
Nature biotechnology 2002;20(3):243-9.
2002: Sara Bassilian; Syed Ahmed; Shu K Lim; Laszlo G Boros; Catherine S Mao; W N Paul Lee
Loss of regulation of lipogenesis in the Zucker diabetic rat. II. Changes in stearate and oleate synthesis.
American journal of physiology. Endocrinology and metabolism 2002;282(3):E507-13.
2002: Laszlo G Boros; W N Paul Lee; Vay Liang W Go
A metabolic hypothesis of cell growth and death in pancreatic cancer.
Pancreas 2002;24(1):26-33.
2001: Joan Boren; Marta Cascante; Silvia Marin; B Comín-Anduix; Josep J Centelles; Shu Lim; Sara Bassilian; S Ahmed; W N Paul Lee; Laszlo G Boros
Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells.
The Journal of biological chemistry 2001;276(41):37747-53.
2001: Laszlo G Boros; R D Williams
Isofenphos induced metabolic changes in K562 myeloid blast cells.
Leukemia research 2001;25(10):883-90.
2001: B Comín-Anduix; Joan Boren; S Martinez; C Moro; Josep J Centelles; R Trebukhina; N Petushok; W N Paul Lee; Laszlo G Boros; Marta Cascante
The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study.
European journal of biochemistry / FEBS 2001;268(15):4177-82.
2001: Laszlo G Boros; Károly Lapis; Béla Szende; Rita Tömösközi-Farkas; A Balogh; Joan Boren; Silvia Marin; Marta Cascante; Márta Hidvégi
Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells.
Pancreas 2001;23(2):141-7.
2001: Laszlo G Boros; Sara Bassilian; S Lim; W N Paul Lee
Genistein inhibits nonoxidative ribose synthesis in MIA pancreatic adenocarcinoma cells: a new mechanism of controlling tumor growth.
Pancreas 2001;22(1):1-7.
2000: W N Paul Lee; Sara Bassilian; S Lim; Laszlo G Boros
Loss of regulation of lipogenesis in the Zucker diabetic (ZDF) rat.
American journal of physiology. Endocrinology and metabolism 2000;279(2):E425-32.
2000: Laszlo G Boros
Population thiamine status and varying cancer rates between western, Asian and African countries.
Anticancer research 2000;20(3B):2245-8.
2000: Laszlo G Boros; John S Torday; S Lim; Sara Bassilian; Marta Cascante; W N Paul Lee
Transforming growth factor beta2 promotes glucose carbon incorporation into nucleic acid ribose through the nonoxidative pentose cycle in lung epithelial carcinoma cells.
Cancer research 2000;60(5):1183-5.
2000: Marta Cascante; Josep J Centelles; R L Veech; W N Paul Lee; Laszlo G Boros
Role of thiamin (vitamin B-1) and transketolase in tumor cell proliferation.
Nutrition and cancer 2000;36(2):150-4.
1999: B Raïs; B Comin; Joaquim Puigjaner; JL Brandes; E Creppy; D Saboureau; R Ennamany; W N Paul Lee; Laszlo G Boros; Marta Cascante
Oxythiamine and dehydroepiandrosterone induce a G1 phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle.
FEBS letters 1999;456(1):113-8.
1998: Peter Muscarella; Laszlo G Boros; William E Fisher; Cameron Rink; W Scott Melvin
Oral dehydroepiandrosterone inhibits the growth of human pancreatic cancer in nude mice.
The Journal of surgical research 1998;79(2):154-7.
1998: Laszlo G Boros; R D Williams
Chronic isofenphos poisoning: case report of agnogenic myeloid metaplasia with a rapid progression into acute myeloid leukemia.
Leukemia research 1998;22(9):849-51.
1998: Laszlo G Boros; JL Brandes; Fouza Yusuf; Marta Cascante; R D Williams; WJ Schirmer
Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action.
Medical hypotheses 1998;50(6):501-6.
1998: W N Paul Lee; Laszlo G Boros; Joaquim Puigjaner; Sara Bassilian; S Lim; Marta Cascante
Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose.
The American journal of physiology 1998;274(5 Pt 1):E843-51.
1998: William E Fisher; Peter Muscarella; Laszlo G Boros; WJ Schirmer
Variable effect of streptozotocin-diabetes on the growth of hamster pancreatic cancer (H2T) in the Syrian hamster and nude mouse.
Surgery 1998;123(3):315-20.
1998: William E Fisher; T A Doran; Peter Muscarella; Laszlo G Boros; E Christopher Ellison; WJ Schirmer
Expression of somatostatin receptor subtype 1-5 genes in human pancreatic cancer.
Journal of the National Cancer Institute 1998;90(4):322-4.
1998: Laszlo G Boros; JL Brandes; W N Paul Lee; Marta Cascante; Joaquim Puigjaner; E Revesz; T M Bray; WJ Schirmer; W Scott Melvin
Thiamine supplementation to cancer patients: a double edged sword.
Anticancer research 1998;18(1B):595-602.
1998: Laszlo G Boros; P W Lee; JL Brandes; Marta Cascante; Peter Muscarella; WJ Schirmer; W Scott Melvin; E Christopher Ellison
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
Medical hypotheses 1998;50(1):55-9.
1997: Laszlo G Boros; Joaquim Puigjaner; Marta Cascante; W N Paul Lee; JL Brandes; Sara Bassilian; Fouza Yusuf; R D Williams; Peter Muscarella; W Scott Melvin; WJ Schirmer
Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation.
Cancer research 1997;57(19):4242-8.
1997: W Scott Melvin; Laszlo G Boros; Peter Muscarella; JL Brandes; J A Johnson; William E Fisher; WJ Schirmer; E Christopher Ellison
Dehydroepiandrosterone-sulfate inhibits pancreatic carcinoma cell proliferation in vitro and in vivo.
Surgery 1997;121(4):392-7.
1996: William E Fisher; Laszlo G Boros; WJ Schirmer
Insulin promotes pancreatic cancer: evidence for endocrine influence on exocrine pancreatic tumors.
The Journal of surgical research 1996;63(1):310-3.
1996: Patricia Smith Choban; T Mcknight; Louis Flancbaum; Carol L K Sabourin; GN Bijur; Laszlo G Boros; J Marley; JC Burge; Fredika Robertson
Characterization of a murine model of acute lung injury (ALI): a prominent role for interleukin-1.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 1996;9(2):95-109.
1995: Fredika Robertson; A E Pellegrini; MS Ross; AS Oberyszyn; Laszlo G Boros; GN Bijur; Carol L K Sabourin; Tatiana M Oberyszyn
Interleukin-1alpha gene expression during wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1995;3(4):473-84.
1995: William E Fisher; Laszlo G Boros; WJ Schirmer
Reversal of enhanced pancreatic cancer growth in diabetes by insulin.
Surgery 1995;118(2):453-7; discussion 457-8.
1995: William E Fisher; Laszlo G Boros; Thomas M O'Dorisio; M Sue O'Dorisio; WJ Schirmer
GI hormonal changes in diabetes influence pancreatic cancer growth.
The Journal of surgical research 1995;58(6):754-8.
1994: Fredika Robertson; GN Bijur; AS Oberyszyn; A E Pellegrini; Laszlo G Boros; Carol L K Sabourin; Tatiana M Oberyszyn
Granulocyte-macrophage colony stimulating factor gene expression and function during tumor promotion.
Carcinogenesis 1994;15(5):1017-29.
1993: Laszlo G Boros; J Damico; Louis Flancbaum; M C Townsend; Philip D Beckley; S D Jones
An automatized computer-method utilizing Procomm Plus and DataEase (4.2) PC and SAS (6.06) mainframe software for isolated, perfused guinea-pig heart studies.
Computer methods and programs in biomedicine 1993;39(3-4):271-84.
1993: Tatiana M Oberyszyn; Carol L K Sabourin; GN Bijur; AS Oberyszyn; Laszlo G Boros; Fredika Robertson
Interleukin-1 alpha gene expression and localization of interleukin-1 alpha protein during tumor promotion.
Molecular carcinogenesis 1993;7(4):238-48.
1992: Laszlo G Boros; C Lepow; F Ruland; V Starbuck; S Jones; Louis Flancbaum; M C Townsend
CD-ROM source data uploaded to the operating and storage devices of an IBM 3090 mainframe through a PC terminal.
Computer methods and programs in biomedicine 1992;38(2-3):77-89.