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Roman Thomas

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Sampurna Chatterjee; Gerhard Christofori; Davide Frasca; Lukas C Heukamp; Mirjam Koker; Katharina König; Lydia Meder; Bernd Neumaier; Martin Peifer; Daniel Rauh; Jakob Schöttle; Maike Siobal; Roman K Thomas; Rolf A Brekken; Reinhard Buettner; Caroline Wieczorek; Jürgen Wolf; Roland T Ullrich
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
Jingchuan Zhang; Lin Zhang; Guanshan Zhu; A Nigel Brooks; Zhengwei Dong; ShuQiong Fan; Qunsheng Ji; Elaine Kilgour; Ming Li; Kunji Liu; Florian Malchers; Ziliang Qian; Paul D Smith; Xinying Su; Lili Tang; Roman K Thomas; Liang Xie; YanPing Xu; XiaoLu Yin; Ping Zhan; Paul R Gavine
Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models.
Katja Höpker; Safiya Khurshid; Tülay Kisner; Peter Kurschat; Tobias Lamkemeyer; Max C Liebau; Drew Lowery; René H Medema; Roman Ulrich Müller; H Christian Reinhardt; Ulrike Resch; Frederik Roels; Fabian Röther; Bernhard Schermer; Katharina Schilberg; Björn Schumacher; Tamina Seeger-Nukpezah; Martin L Sos; Roman K Thomas; Michael B Yaffe; Shuhua Chen; Francesca Fabretti; Matthias Fischer; Matthias Gaestel; Henning Hagmann; Pia Hasskamp; Lukas Heukamp; Malte P Bartram; Thomas Benzing
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

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All Publications

2013: Sampurna Chatterjee; Gerhard Christofori; Davide Frasca; Lukas C Heukamp; Mirjam Koker; Katharina König; Lydia Meder; Bernd Neumaier; Martin Peifer; Daniel Rauh; Jakob Schöttle; Maike Siobal; Roman K Thomas; Rolf A Brekken; Reinhard Buettner; Caroline Wieczorek; Jürgen Wolf; Roland T Ullrich
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
The Journal of clinical investigation 2013;123(4):1732-40.
2012: Jingchuan Zhang; Lin Zhang; Guanshan Zhu; A Nigel Brooks; Zhengwei Dong; ShuQiong Fan; Qunsheng Ji; Elaine Kilgour; Ming Li; Kunji Liu; Florian Malchers; Ziliang Qian; Paul D Smith; Xinying Su; Lili Tang; Roman K Thomas; Liang Xie; YanPing Xu; XiaoLu Yin; Ping Zhan; Paul R Gavine
Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(24):6658-67.
2012: Katja Höpker; Safiya Khurshid; Tülay Kisner; Peter Kurschat; Tobias Lamkemeyer; Max C Liebau; Drew Lowery; René H Medema; Roman Ulrich Müller; H Christian Reinhardt; Ulrike Resch; Frederik Roels; Fabian Röther; Bernhard Schermer; Katharina Schilberg; Björn Schumacher; Tamina Seeger-Nukpezah; Martin L Sos; Roman K Thomas; Michael B Yaffe; Shuhua Chen; Francesca Fabretti; Matthias Fischer; Matthias Gaestel; Henning Hagmann; Pia Hasskamp; Lukas Heukamp; Malte P Bartram; Thomas Benzing
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
The EMBO journal 2012;31(20):3961-75.
2012: Martin L Sos; Roland T Ullrich; Viktor V Vintonyak; Herbert Waldmann; Andrey P Antonchick; Hyatt Balke-Want; Reinhard Büttner; Felix Dietlein; Patrick A Eyers; Johannes M Heuckmann; Lukas Heukamp; Stefanie Heynck; Mirjam Koker; Florian Malchers; Christian Müller; Takashi Ninomiya; Martin Peifer; Daniel Rauh; André Richters; Peter M Schneider; Jakob Schöttle; Danila Seidel; Roman K Thomas
A framework for identification of actionable cancer genome dependencies in small cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(42):17034-9.
2012: Johannes M Heuckmann; Daniel Rauh; Roman K Thomas
Epidermal growth factor receptor (EGFR) signaling and covalent EGFR inhibition in lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(27):3417-20.
2012: Johannes M Heuckmann; Lukas Heukamp; Mirjam Koker; Ralf Küppers; Christine M Lovly; Florian Malchers; Lydia Meder; William Pao; Martin Peifer; Martin L Sos; Hyatt Balke-Want; Roman K Thomas
Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(17):4682-90.
2012: Juliann Chmielecki; Utpal P Davé; Rebecca S Dean; Jennifer Giltnane; Clayton J Hollis; Katherine Hutchinson; Madan Jagasia; Annette S Kim; Martin Peifer; Nicholas D Socci; Roman K Thomas; Agnes Viale; Ashwini Yenamandra; William Pao
Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Genes, chromosomes & cancer 2012;51(1):54-65.
2011: Christine M Lovly; Roman K Thomas; Heidi Chen; Elisa de Stanchina; Johannes M Heuckmann; Chris Liang; William Pao
Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors.
Cancer research 2011;71(14):4920-31.
2011: Juliann Chmielecki; Elisa de Stanchina; Jasmine Foo; Michelle S Ginsberg; Katherine Hutchinson; Akira Inoue; Mark G Kris; Marc Ladanyi; Franziska Michor; Vincent A Miller; Kadoaki Ohashi; Geoffrey R Oxnard; Nicholas D Socci; Romel Somwar; Martin L Sos; Roman K Thomas; Agnes Viale; Lu Wang; Katherine R Amato; Maria Arcila; William Pao
Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.
Science translational medicine 2011;3(90):90ra59.
2011: Thomas Zander; Sascha Ansén; Marc Beyer; Sabine Classen; Svenja Debey-Pascher; Karl-Stefan Delank; Walburga Engel-Riedel; Birgit Gathof; Moritz Hahn; Andrea Hofmann; Daniela Maisel; Cornelia Mauch; Joachim L Schultze; Andrea Staratschek-Jox; Erich Stoelben; Roman K Thomas; H-Erich Wichmann; Jürgen Wolf
Blood-based gene expression signatures in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(10):3360-7.
2011: Thomas Zander; Matthias Scheffler; Lucia Nogova; Carsten Kobe; Walburga Engel-Riedel; Martin Hellmich; Irini Papachristou; Karin Toepelt; Andreas Draube; Lukas Heukamp; Reinhard Buettner; Yon D Ko; Roland T Ullrich; Egbert Smit; Ronald Boellaard; Adriaan A Lammertsma; Michael Hallek; Andreas H Jacobs; Andreas Schlesinger; Karin Schulte; Silvia Querings; Erich Stoelben; Bernd Neumaier; Roman K Thomas; Markus Dietlein; Jürgen Wolf
Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(13):1701-8.
2011: Kwon-Sik Park; CRAIG PEACOCK; Martin Peifer; Martin L Sos; Tim Stearns; Anette Szczepny; Roman K Thomas; D Neil Watkins; Jing Yuan; Samara Bennett; Katie Bernard; Tracey J Brown; Silvia Buonamici; James Kenneth Chen; Jamie F Conklin; Wendy L Devereux; Marion Dorsch; Jeanette Falzon; Ribo Guo; Anthony N Karnezis; Moe R Mahjoub; Ana Markovic; Luciano Gaston Martelotto; Cory A Ocasio; Beatrice Ospina; Julien Sage
A crucial requirement for Hedgehog signaling in small cell lung cancer.
Nature medicine 2011;17(11):1504-8.
2011: Silvia Querings; Janine Altmüller; Sascha Ansén; Thomas Zander; Danila Seidel; Franziska Gabler; Martin Peifer; Eva Markert; Kathryn Stemshorn; Bernd Timmermann; Beate Saal; Stefan Klose; Karen Ernestus; Matthias Scheffler; Walburga Engel-Riedel; Erich Stoelben; Elisabeth Brambilla; Jürgen Wolf; Peter Nürnberg; Roman K Thomas
Benchmarking of mutation diagnostics in clinical lung cancer specimens.
PloS one 2011;6(5):e19601.
2010: Juliann Chmielecki; Martin Peifer; Peilin Jia; Nicholas D Socci; Katherine Hutchinson; Agnes Viale; Zhongming Zhao; Roman K Thomas; William Pao
Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer.
Nucleic acids research 2010;38(20):6985-96.
2010: Anke Bill; Anton Schmitz; Barbara Albertoni; Jin-Na Song; Lukas C Heukamp; David Walrafen; Franziska Thorwirth; Peter J Verveer; Sebastian Zimmer; Lisa Meffert; Arne Schreiber; Sampurna Chatterjee; Roman K Thomas; Roland T Ullrich; Thorsten Lang; Michael Famulok
Cytohesins are cytoplasmic ErbB receptor activators.
Cell 2010;143(2):201-11.
2010: Chang-Qi Zhu; Keyue Ding; Dan Strumpf; Barbara A Weir; Matthew Meyerson; Nathan Pennell; Roman K Thomas; Katsuhiko Naoki; Christine Ladd-Acosta; Ni Liu; Melania Pintilie; Sandy D Der; Lesley Seymour; Igor Jurisica; Frances A Shepherd; Ming-Sound Tsao
Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(29):4417-24.
2010: Vijaykumar Pawar; Martin L Sos; Haridas B Rode; Matthias Rabiller; Stefanie Heynck; Willem A L van Otterlo; Roman K Thomas; Daniel Rauh
Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor.
Journal of medicinal chemistry 2010;53(7):2892-901.
2010: Qing Sheng; Xinggang Liu; Eleanor Fleming; Karen Yuan; Huiying Piao; Jinyun Chen; Zeinab Moustafa; Roman K Thomas; Heidi Greulich; Anna Schinzel; Sara Zaghlul; David Batt; Seth Ettenberg; Matthew Meyerson; Birgit Schoeberl; Andrew L Kung; William C Hahn; Ronny Drapkin; David M Livingston; Joyce F Liu
An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.
Cancer cell 2010;17(3):298-310.
2010: Sascha Ansén; Christopher Bangard; Silvia Querings; Franziska Gabler; Matthias Scheffler; Daniela Seidel; Beate Saal; Thomas Zander; Lucia Nogová; Karin Töpelt; Eva Markert; Erich Stoelben; Karen Ernestus; Roman K Thomas; Jürgen Wolf
Osteoblastic response in patients with non-small cell lung cancer with activating EGFR Mutations and bone metastases during treatment with EGFR kinase inhibitors.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(3):407-9.
2010: Martin L Sos; Haridas B Rode; Stefanie Heynck; Martin Peifer; Florian Fischer; Sabine Klüter; Vijaykumar Pawar; Cecile Reuter; Johannes M Heuckmann; Jonathan Weiss; Lars Ruddigkeit; Matthias Rabiller; Mirjam Koker; Jeffrey R Simard; Matthäus Getlik; Yuki Yuza; Tzu-Hsiu Chen; Heidi Greulich; Roman K Thomas; Daniel Rauh
Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation.
Cancer research 2010;70(3):868-74.
2010: Martin Peifer; Jonathan Weiss; Martin L Sos; Mirjam Koker; Stefanie Heynck; Christian Netzer; Stefanie Fischer; Haridas Rode; Daniel Rauh; Jörg Rahnenführer; Roman K Thomas
Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling.
PloS one 2010;5(1):e8919.
2009: Martin L Sos; Roman K Thomas
Systematically linking drug susceptibility to cancer genome aberrations.
Cell cycle (Georgetown, Tex.) 2009;8(22):3652-6.
2009: Lucia Nogová; Ronald Boellaard; Carsten Kobe; Nikie Hoetjes; Thomas Zander; Stefan Hubert Gross; Sasa Dimitrijevic; Ted Pellas; Wolfgang Eschner; Katja Schmidt; Christopher Bangard; Wendy Hayes; Roman K Thomas; Markus Dietlein; Giuseppe Giaccone; Otto S Hoekstra; Adriaan A Lammertsma; Jürgen Wolf
Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(11):1815-9.
2009: Alex H Ramos; Amit Dutt; Craig Mermel; Sven Perner; Jeonghee Cho; Christopher J Lafargue; Laura A Johnson; Ann-Cathrin Stiedl; Kumiko E Tanaka; Adam J Bass; Jordi Barretina; Barbara A Weir; Rameen Beroukhim; Roman K Thomas; John D Minna; Lucian R Chirieac; Neal Lindeman; Thomas J Giordano; David G Beer; Patrick Wagner; Ignacio I Wistuba; Mark A Rubin; Matthew Meyerson
Amplification of chromosomal segment 4q12 in non-small cell lung cancer.
Cancer biology & therapy 2009;8(21):2042-50.
2009: Martin L Sos; Stefanie Fischer; Roland Ullrich; Martin Peifer; Johannes M Heuckmann; Mirjam Koker; Stefanie Heynck; Isabel Stückrath; Jonathan Weiss; Florian Fischer; Kathrin Michel; Aviva Goel; Lucia Regales; Katerina A Politi; Samanthi Perera; Matthäus Getlik; Lukas C Heukamp; Sascha Ansén; Thomas Zander; Rameen Beroukhim; Hamid Kashkar; Kevan M Shokat; William R Sellers; Daniel Rauh; Christine Orr; Klaus P Hoeflich; Lori Friedman; Kwok-Kin Wong; William Pao; Roman K Thomas
Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18351-6.
2009: Martin L Sos; Mirjam Koker; Barbara A Weir; Stefanie Heynck; Rosalia Rabinovsky; Thomas Zander; Jens M Seeger; Jonathan Weiss; Florian Fischer; Peter Frommolt; Kathrin Michel; Martin Peifer; Craig Mermel; Luc Girard; Michael Peyton; Adi F Gazdar; John D Minna; Levi A Garraway; Hamid Kashkar; William Pao; Matthew Meyerson; Roman K Thomas
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR.
Cancer research 2009;69(8):3256-61.
2009: Thomas LaFramboise; Wendy Winckler; Roman K Thomas
A flexible rank-based framework for detecting copy number aberrations from array data.
Bioinformatics (Oxford, England) 2009;25(6):722-8.
2009: Yixuan Gong; Evelyn Yao; Ronglai Shen; Aviva Goel; Maria Arcila; Julie T Feldstein; Maureen F Zakowski; Stanley Frankel; Martin Peifer; Roman K Thomas; Marc Ladanyi; William Pao
High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507).
PloS one 2009;4(10):e7273.
2008: Takeshi Shimamura; Danan Li; Hongbin Ji; Henry J Haringsma; Elizabeth Liniker; Christa L Borgman; April M Lowell; Yuko Minami; Kate McNamara; Samanthi A Perera; Sara Zaghlul; Roman K Thomas; Heidi Greulich; Susumu Kobayashi; Lucian R Chirieac; Robert F Padera; Shigeto Kubo; Masaya Takahashi; Daniel G Tenen; Matthew Meyerson; Kwok-Kin Wong; Geoffrey I Shapiro
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance.
Cancer research 2008;68(14):5827-38.
2008: Jenifer L Marks; Yixuan Gong; Dhananjay Chitale; Ben Golas; Michael D McLellan; Yumi Kasai; Li Ding; Elaine R Mardis; Richard K Wilson; David B Solit; Ross Levine; Kathrin Michel; Roman K Thomas; Valerie W Rusch; Marc Ladanyi; William Pao
Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma.
Cancer research 2008;68(14):5524-8.
2008: Martin L Sos; Thomas Zander; Roman K Thomas; Andrea Staratschek-Jox; Julia Claasen; Jürgen Wolf
Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):170-3.
2008: William M Lin; Alissa C Baker; Rameen Beroukhim; Wendy Winckler; Whei Feng; Jennifer M Marmion; Elisabeth Laine; Heidi Greulich; Hsiuyi Tseng; Casey Gates; F Stephen Hodi; Glenn Dranoff; William R Sellers; Roman K Thomas; Matthew Meyerson; Todd R Golub; Reinhard Dummer; Meenhard Herlyn; Gad Getz; Levi A Garraway
Modeling genomic diversity and tumor dependency in malignant melanoma.
Cancer research 2008;68(3):664-73.
2008: Peter Frommolt; Roman K Thomas
Standardized high-throughput evaluation of cell-based compound screens.
BMC bioinformatics 2008;9():475.
2007: Y Minami; Takeshi Shimamura; Keerti V Shah; Thomas LaFramboise; Karen A Glatt; E Liniker; C L Borgman; H J Haringsma; Whei Feng; Barbara A Weir; April M Lowell; Jeffrey C Lee; J Wolf; Geoffrey I Shapiro; Kwok-Kin Wong; Matthew Meyerson; Roman K Thomas
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272.
Oncogene 2007;26(34):5023-7.
2007: Danan Li; Takeshi Shimamura; Hongbin Ji; Liang Chen; Henry J Haringsma; Kate McNamara; Mei-Chih Liang; Samanthi A Perera; Sara Zaghlul; Christa L Borgman; Shigeto Kubo; Masaya Takahashi; Yanping Sun; Lucian R Chirieac; Robert F Padera; Neal Lindeman; Pasi A Janne; Roman K Thomas; Matthew Meyerson; Michael J Eck; Jeffrey A Engelman; Geoffrey I Shapiro; Kwok-Kin Wong
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
Cancer cell 2007;12(1):81-93.
2007: Hongbin Ji; Zhenxiong Wang; Samanthi A Perera; Danan Li; Mei-Chih Liang; Sara Zaghlul; Kate McNamara; Liang Chen; Mitchell S Albert; Yanping Sun; Ruqayyah Al-Hashem; Lucian R Chirieac; Robert F Padera; Roderick T Bronson; Roman K Thomas; Levi A Garraway; Pasi A Janne; Bruce E Johnson; Lynda Chin; Kwok-Kin Wong
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Cancer research 2007;67(10):4933-9.
2007: Andreas Draube; Marc Beyer; Stephan Schumer; Roman K Thomas; Bastian von Tresckow; Thomas Christian Koslowsky; Christian F Krieglstein; Joachim L Schultze; Jürgen Wolf
Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(4):359-69.
2006: Roland Schmitz; Roman K Thomas; Anne C Harttrampf; Claudia Wickenhauser; Joachim L Schultze; Martin-Leo Hansmann; Jürgen Wolf; Ralf Küppers
The major subtypes of human B-cell lymphomas lack mutations in BCL-2 family member BAD.
International journal of cancer. Journal international du cancer 2006;119(7):1738-40.
2006: Torstein Tengs; Jeff C Lee; J Guillermo Paez; Xiaojun Zhao; Thomas LaFramboise; Georgia Giannoukos; Roman K Thomas
A transforming MET mutation discovered in non-small cell lung cancer using microarray-based resequencing.
Cancer letters 2006;239(2):227-33.
2006: Roman K Thomas; Barbara Weir; Matthew Meyerson
Genomic approaches to lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 2):4384s-4391s.
2006: Takeshi Shimamura; Hongbin Ji; Yuko Minami; Roman K Thomas; April M Lowell; Kinjal Shah; Heidi Greulich; Karen A Glatt; Matthew Meyerson; Geoffrey I Shapiro; Kwok-Kin Wong
Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272.
Cancer research 2006;66(13):6487-91.
2006: Hongbin Ji; Xiaojun Zhao; Yuki Yuza; Takeshi Shimamura; Danan Li; Alexei Protopopov; Boonim L Jung; Kate McNamara; Huili Xia; Karen A Glatt; Roman K Thomas; Hidefumi Sasaki; James W Horner; Michael J Eck; Albert Mitchell; Yangping Sun; Ruqayyah Al-Hashem; Roderick T Bronson; Sridhar K Rabindran; Carolyn Discafani; Elizabeth Maher; Geoffrey I Shapiro; Matthew Meyerson; Kwok-Kin Wong
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7817-22.
2005: Roman K Thomas; Martin L Sos; Thomas Zander; Ozlem Mani; Alexey Popov; Daniel Berenbrinker; Sigrun Smola-Hess; Joachim L Schultze; Jürgen Wolf
Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(22):8186-94.
2005: Marc Beyer; Matthias Kochanek; Kamruz Darabi; Alexey Popov; Markus Jensen; Elmar Endl; Percy A Knolle; Roman K Thomas; Michael S von Bergwelt-Baildon; Svenja Debey; Michael Hallek; Joachim L Schultze
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine.
Blood 2005;106(6):2018-25.
2005: Jeanette R Doerr; Cindy S Malone; Francesca M Fike; Melinda S Gordon; Shahe V Soghomonian; Roman K Thomas; Qian Tao; Paul G Murray; Volker Diehl; Michael A Teitell; Randolph Wall
Patterned CpG methylation of silenced B cell gene promoters in classical Hodgkin lymphoma-derived and primary effusion lymphoma cell lines.
Journal of molecular biology 2005;350(4):631-40.
2005: Daniel Re; Roman K Thomas; Karolin Behringer; Volker Diehl
From Hodgkin disease to Hodgkin lymphoma: biologic insights and therapeutic potential.
Blood 2005;105(12):4553-60.
2005: Roman K Thomas; Heidi Greulich; Yuki Yuza; Jeffrey C Lee; Torstein Tengs; Whei Feng; Tzu-Hsiu Chen; E Nickerson; J Simons; Michael Egholm; Jonathan M Rothberg; William R Sellers; Matthew Meyerson
Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors.
Cold Spring Harbor symposia on quantitative biology 2005;70():73-81.
2005: Daniel Re; Roman K Thomas; Thomas Zander; Volker Diehl
Problems and promises of targeted therapy for Hodgkin's lymphoma.
Nature clinical practice. Oncology 2005;2(1):2-3.
2004: Roman K Thomas; Claudia Wickenhauser; Samir Tawadros; Volker Diehl; Ralf Küppers; Jürgen Wolf; Roland Schmitz
Mutational analysis of the IkappaBalpha gene in activated B cell-like diffuse large B-cell lymphoma.
British journal of haematology 2004;126(1):50-4.
2004: Roman K Thomas; Claudia Wickenhauser; Martin Hafner; Hans Tesch; Volker Diehl; Jürgen Wolf; Martina Vockerodt
Repeated clonal relapses in classical Hodgkin's lymphoma and the occurrence of a clonally unrelated diffuse large B cell non-Hodgkin lymphoma in the same patient.
Leukemia & lymphoma 2004;45(5):1065-9.
2004: Volker Diehl; Roman K Thomas; Daniel Re
Part II: Hodgkin's lymphoma--diagnosis and treatment.
The lancet oncology 2004;5(1):19-26.
2004: Roman K Thomas; Daniel Re; Jürgen Wolf; Volker Diehl
Part I: Hodgkin's lymphoma--molecular biology of Hodgkin and Reed-Sternberg cells.
The lancet oncology 2004;5(1):11-8.
2003: Roman K Thomas; Volker Diehl
Unhappy neighbourhood: spatial genome organisation and lymphomagenesis in B cells.
Lancet 2003;362(9399):1868-70.
2003: Daniel Re; Petr Starostik; Nadia Massoudi; Andrea Staratschek-Jox; Volker Dries; Roman K Thomas; Volker Diehl; Jürgen Wolf
Allelic losses on chromosome 6q25 in Hodgkin and Reed Sternberg cells.
Cancer research 2003;63(10):2606-9.
2002: Roman K Thomas; Anne Kallenborn; Claudia Wickenhauser; Joachim L Schultze; Andreas Draube; Martina Vockerodt; Daniel Re; Volker Diehl; Jürgen Wolf
Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells.
The American journal of pathology 2002;160(4):1521-8.
2002: Roman K Thomas; Daniel Re; Thomas Zander; Jürgen Wolf; Volker Diehl
Epidemiology and etiology of Hodgkin's lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13 Suppl 4():147-52.
2001: Andrea Staratschek-Jox; Roman K Thomas; Thomas Zander; Nadia Massoudi; Martin Kornacker; Jörn Bullerdiek; Christa Fonatsch; Volker Diehl; Jürgen Wolf
Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236.
British journal of cancer 2001;84(3):381-7.