FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Thommey Thomas

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Mouse

Devices

Drug Delivery Systems

Co-author Network

Publications

TOP 3
Seok Ki Choi; Ankur M Desai; Mark M Banaszak Holl; Alina Kotlyar; Kelly McCarthy; Andrzej Myc; Bradford G Orr; Justin Ezekiel Silpe; Madhuresh Sumit; Thommey P Thomas; Pamela Tinmoi Wong; James R Baker
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface.
Brent B Ward; Hong Zong; Xue-Min Cheng; Ankur Desai; Baohua Huang; Alina E Kotlyar; Pascale Leroueil; Xiangyang Shi; Thommey P Thomas; Abraham F L Van Der Spek; Mark Vartanian; James R Baker Jr
Sustained analgesia achieved through esterase-activated morphine prodrugs complexed with PAMAM dendrimer.
Thommey P Thomas; Hong Zong; Seok Ki Choi; Ankur M Desai; Jeremy Gam; Baohua Huang; Melvin Joice; Alina Kotlyar; Justin E Silpe; James R Baker Jr
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Thommey Thomas (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Seok Ki Choi; Ankur M Desai; Mark M Banaszak Holl; Alina Kotlyar; Kelly McCarthy; Andrzej Myc; Bradford G Orr; Justin Ezekiel Silpe; Madhuresh Sumit; Thommey P Thomas; Pamela Tinmoi Wong; James R Baker
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface.
ACS nano 2013;7(1):214-28.
2013: Brent B Ward; Hong Zong; Xue-Min Cheng; Ankur Desai; Baohua Huang; Alina E Kotlyar; Pascale Leroueil; Xiangyang Shi; Thommey P Thomas; Abraham F L Van Der Spek; Mark Vartanian; James R Baker Jr
Sustained analgesia achieved through esterase-activated morphine prodrugs complexed with PAMAM dendrimer.
Pharmaceutical research 2013;30(1):247-56.
2012: Thommey P Thomas; Hong Zong; Seok Ki Choi; Ankur M Desai; Jeremy Gam; Baohua Huang; Melvin Joice; Alina Kotlyar; Justin E Silpe; James R Baker Jr
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.
Molecular pharmaceutics 2012;9(9):2669-76.
2012: Thommey P Thomas; Jing Yong Ye; Zhengyi Cao; Yu-Chung Chang; Alina Kotlyar; Theodore B Norris; Suyang Qin; Rameshwer Shukla; James R Baker Jr
Optical fiber-based in vivo quantification of growth factor receptors.
Cancer 2012;118(8):2148-56.
2012: Hong Zong; Mark M Banaszak Holl; Ankur M Desai; Jeremy J Gam; Alina Kotlyar; Kyung-Hoon Lee; Pascale Leroueil; Ming-hsin Li; Thommey P Thomas; Yuehua Zhang; James R Baker Jr
Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio.
Biomacromolecules 2012;13(4):982-91.
2012: Seok Ki Choi; Ankur Desai; Alina Kotlyar; Ming-Hsin Li; Thommey P Thomas; James R Baker Jr
Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2012;11(4):653-60.
2012: Ming-Hsin Li; Thommey P Thomas; Mark M Banaszak Holl; Seok Ki Choi; Ankur Desai; Alina Kotlyar; Kyung-Hoon Lee; James R Baker Jr
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.
European journal of medicinal chemistry 2012;47(1):560-72.
2011: Thommey P Thomas; Zhengyi Cao; Sascha N Goonewardena; Alina Kotlyar; Pascale Leroueil; Istvan J Majoros; James R Baker Jr
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis.
Arthritis and rheumatism 2011;63(9):2671-80.
2011: Douglas Gurnett Mullen; Daniel Q McNerny; Ankur Desai; Xue-min Cheng; Stassi C Dimaggio; Alina Kotlyar; Yueyang Zhong; Suyang Qin; Christopher V Kelly; Thommey P Thomas; Istvan J Majoros; Bradford G Orr; James R Baker Jr; Mark M Banaszak Holl
Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.
Bioconjugate chemistry 2011;22(4):679-89.
2011: Yuehua Zhang; Thommey P Thomas; Kyung-Hoon Lee; Minghsin Li; Hong Zong; Ankur M Desai; Alina Kotlyar; Baohua Huang; Mark M Banaszak Holl; James R Baker Jr
Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent.
Bioorganic & medicinal chemistry 2011;19(8):2557-64.
2010: Thommey P Thomas; Baohua Huang; Ankur Desai; Hong Zong; Xue-min Cheng; Alina Kotlyar; Pascale R Leroueil; Thomas Dunham; Abraham F L Van Der Spek; Brent B Ward; James R Baker Jr
Plasma-mediated release of morphine from synthesized prodrugs.
Bioorganic & medicinal chemistry letters 2010;20(21):6250-3.
2010: Thommey P Thomas; Seok Ki Choi; Ming-Hsin Li; Alina Kotlyar; James R Baker Jr
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery.
Bioorganic & medicinal chemistry letters 2010;20(17):5191-4.
2010: Yu-Chung Chang; Jing Yong Ye; Thommey P Thomas; Zhengyi Cao; Alina Kotlyar; Eric R Tkaczyk; James R Baker Jr; Theodore B Norris
Fiber-optic multiphoton flow cytometry in whole blood and in vivo.
Journal of biomedical optics 2010;15(4):047004.
2010: Yunbo Guo; Jing Yong Ye; Charles Divin; Baohua Huang; Thommey P Thomas; James R Baker Jr; Theodore B Norris
Real-time biomolecular binding detection using a sensitive photonic crystal biosensor.
Analytical chemistry 2010;82(12):5211-8.
2010: Seok Ki Choi; Thommey P Thomas; Ming-Hsin Li; Alina Kotlyar; Ankur Desai; James R Baker Jr
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate.
Chemical communications (Cambridge, England) 2010;46(15):2632-4.
2010: Baohua Huang; Ankur Desai; Shengzhuang Tang; Thommey P Thomas; James R Baker Jr
The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release.
Organic letters 2010;12(7):1384-7.
2010: Thommey P Thomas; Rameshwer Shukla; Alina Kotlyar; Jolanta F Kukowska-Latallo; James R Baker Jr
Dendrimer-based tumor cell targeting of fibroblast growth factor-1.
Bioorganic & medicinal chemistry letters 2010;20(2):700-3.
2009: Thommey P Thomas; Istvan J Majoros; Alina Kotlyar; Douglas Mullen; Mark M Banaszak Holl; James R Baker Jr
Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations.
Biomacromolecules 2009;10(12):3207-14.
2009: Baohua Huang; Shengzhuang Tang; Ankur Desai; Xue-min Cheng; Alina Kotlyar; Abraham F L Van Der Spek; Thommey P Thomas; James R Baker Jr
Human plasma-mediated hypoxic activation of indolequinone-based naloxone pro-drugs.
Bioorganic & medicinal chemistry letters 2009;19(17):5016-20.
2008: Yu-Chung Chang; Jing Yong Ye; Thommey P Thomas; Yi Chen; James R Baker Jr; Theodore B Norris
Two-photon fluorescence correlation spectroscopy through a dual-clad optical fiber.
Optics express 2008;16(17):12640-9.
2008: Rameshwer Shukla; Thommey P Thomas; Ankur M Desai; Alina Kotlyar; Steve J Park; James R Baker Jr
HER2 specific delivery of methotrexate by dendrimer conjugated anti-HER2 mAb.
Nanotechnology 2008;19(29):295102.
2008: Cheng Frank Zhong; Eric R Tkaczyk; Thommey P Thomas; Jing Yong Ye; Andrzej Myc; Anna U Bielinska; Zhengyi Cao; Istvan J Majoros; Balazs Keszler; James R Baker Jr; Theodore B Norris
Quantitative two-photon flow cytometry--in vitro and in vivo.
Journal of biomedical optics 2008;13(3):034008.
2008: Kevin J Landmark; Stassi Dimaggio; Jesse Ward; Christopher Kelly; Stefan Vogt; Seungpyo Hong; Alina Kotlyar; Andrzej Myc; Thommey P Thomas; James E Penner-Hahn; James R Baker Jr; Mark M Banaszak Holl; Bradford G Orr
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers.
ACS nano 2008;2(4):773-83.
2008: Thommey P Thomas; Rameshwer Shukla; Alina Kotlyar; Bradley Liang; Jing Yong Ye; Theodore B Norris; James R Baker Jr
Dendrimer-epidermal growth factor conjugate displays superagonist activity.
Biomacromolecules 2008;9(2):603-9.
2008: Andrzej Myc; Thomas B Douce; Niharika Ahuja; Alina Kotlyar; Jolanta F Kukowska-Latallo; Thommey P Thomas; James R Baker Jr
Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates.
Anti-cancer drugs 2008;19(2):143-9.
2008: Thommey P Thomas; Jing Yong Ye; Yu-Chung Chang; Alina Kotlyar; Zhengyi Cao; Istvan J Majoros; Theodore B Norris; James R Baker Jr
Investigation of tumor cell targeting of a dendrimer nanoparticle using a double-clad optical fiber probe.
Journal of biomedical optics 2008;13(1):014024.
2007: Xiangyang Shi; Thommey P Thomas; Lukasz A Myc; Alina Kotlyar; James R Baker Jr
Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles.
Physical chemistry chemical physics : PCCP 2007;9(42):5712-20.
2007: Andrzej Myc; Istvan J Majoros; Thommey P Thomas; James R Baker Jr
Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells.
Biomacromolecules 2007;8(1):13-8.
2006: Rameshwer Shukla; Thommey P Thomas; Jennifer L Peters; Ankur M Desai; Jolanta F Kukowska-Latallo; Anil K Patri; Alina Kotlyar; James R Baker Jr
HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb.
Bioconjugate chemistry 2006;17(5):1109-15.
2006: Istvan J Majoros; Andrzej Myc; Thommey P Thomas; Chandan B Mehta; James R Baker Jr
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality.
Biomacromolecules 2006;7(2):572-9.
2005: Rameshwer Shukla; Thommey P Thomas; Jennifer Peters; Alina Kotlyar; Andrzej Myc; James R Baker Jr
Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates.
Chemical communications (Cambridge, England) 2005;(46):5739-41.
2005: Eitaro Nakashima; Rodica Pop-Busui; Roberto Towns; Thommey P Thomas; Yoshiuki Hosaka; Jiro Nakamura; Douglas A Greene; Paul D Killen; Justin Schroeder; Dennis Larkin; Yuk Lam Ho; Martin J Stevens
Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase.
Antioxidants & redox signaling 2005;7(11-12):1530-42.
2005: Istvan J Majoros; Thommey P Thomas; Chandan B Mehta; James R Baker Jr
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy.
Journal of medicinal chemistry 2005;48(19):5892-9.
2005: Jolanta F Kukowska-Latallo; Kimberly A Candido; Zhengyi Cao; Shraddha Nigavekar; Istvan J Majoros; Thommey P Thomas; Lajos Balogh; Dr. Muhammad Khan; James R Baker Jr
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer.
Cancer research 2005;65(12):5317-24.
2005: Thommey P Thomas; Istvan J Majoros; Alina Kotlyar; Jolanta F Kukowska-Latallo; Anna U Bielinska; Andrzej Myc; James R Baker Jr
Targeting and inhibition of cell growth by an engineered dendritic nanodevice.
Journal of medicinal chemistry 2005;48(11):3729-35.
2005: Youngseon Choi; Thommey P Thomas; Alina Kotlyar; Mohammad T Islam; James R Baker Jr
Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting.
Chemistry & biology 2005;12(1):35-43.
2004: Anil K Patri; Andrzej Myc; James Beals; Thommey P Thomas; Neil H Bander; James R Baker Jr
Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy.
Bioconjugate chemistry 2004;15(6):1174-81.
2004: Thommey P Thomas; Anil K Patri; Andrzej Myc; Mon Thiri Myaing; Jing Yong Ye; Theodore B Norris; James R Baker Jr
In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles.
Biomacromolecules 2004;5(6):2269-74.
2004: Thommey P Thomas; Mon Thiri Myaing; Jing Yong Ye; Kimberly A Candido; Alina Kotlyar; James Beals; Peter Cao; Balazs Keszler; Anil K Patri; Theodore B Norris; James R Baker Jr
Detection and analysis of tumor fluorescence using a two-photon optical fiber probe.
Biophysical journal 2004;86(6):3959-65.
2003: Mon Thiri Myaing; Jing Yong Ye; Theodore B Norris; Thommey P Thomas; James R Baker Jr; William J Wadsworth; G Bouwmans; Jonathan C Knight; P St J Russell
Enhanced two-photon biosensing with double-clad photonic crystal fibers.
Optics letters 2003;28(14):1224-6.
2002: Antonio Quintana; Ewa Raczka; Lars T Piehler; Inhan Lee; Andrzej Myc; Istvan J Majoros; Anil K Patri; Thommey P Thomas; James J Mulé; James R Baker Jr
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor.
Pharmaceutical research 2002;19(9):1310-6.
2002: Jing Yong Ye; Mon Thiri Myaing; Theodore B Norris; Thommey P Thomas; James R Baker Jr
Biosensing based on two-photon fluorescence measurements through optical fibers.
Optics letters 2002;27(16):1412-4.
1999: Martin J Stevens; Yoshiuki Hosaka; J A Masterson; S M Jones; Thommey P Thomas; Dennis Larkin
Downregulation of the human taurine transporter by glucose in cultured retinal pigment epithelial cells.
The American journal of physiology 1999;277(4 Pt 1):E760-71.
1999: K Kato; Thommey P Thomas; Martin J Stevens; Douglas A Greene; J Nakamura
2-Chloroadenosine reverses hyperglycemia-induced inhibition of phosphoinositide synthesis in cultured human retinal pigment epithelial cells and prevents reduced nerve conduction velocity in diabetic rats.
Metabolism: clinical and experimental 1999;48(7):827-33.
1998: P Magnani; Thommey P Thomas; Gihan I. Tennekoon; George Henry De Vries; Douglas A Greene; Frank C Brosius III
Regulation of glucose transport in cultured Schwann cells.
Journal of the peripheral nervous system : JPNS 1998;3(1):28-36.
1997: A Karihaloo; K Kato; Douglas A Greene; Thommey P Thomas
Protein kinase and Ca2+ modulation of myo-inositol transport in cultured retinal pigment epithelial cells.
The American journal of physiology 1997;273(2 Pt 1):C671-8.
1996: H Shindo; Thommey P Thomas; Dennis Larkin; A K Karihaloo; H Inada; Toshimasa Onaya; Martin J Stevens; Douglas A Greene
Modulation of basal nitric oxide-dependent cyclic-GMP production by ambient glucose, myo-inositol, and protein kinase C in SH-SY5Y human neuroblastoma cells.
The Journal of clinical investigation 1996;97(3):736-45.
1994: Martin J Stevens; J Dananberg; Eva L Feldman; S A Lattimer; M Kamijo; Thommey P Thomas; H Shindo; Anders A F Sima; Douglas A Greene
The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat.
The Journal of clinical investigation 1994;94(2):853-9.
1994: Thommey P Thomas; Francesca Porcellati; K Kato; Martin J Stevens; W R Sherman; Douglas A Greene
Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo-inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells.
The Journal of clinical investigation 1994;93(6):2718-24.
1993: Thommey P Thomas; Eva L Feldman; J Nakamura; K Kato; M Lien; Martin J Stevens; Douglas A Greene
Ambient glucose and aldose reductase-induced myo-inositol depletion modulate basal and carbachol-stimulated inositol phospholipid metabolism and diacylglycerol accumulation in human retinal pigment epithelial cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9712-6.
1993: Douglas A Greene; Anders A F Sima; Martin J Stevens; Eva L Feldman; Paul D Killen; D N Henry; Thommey P Thomas; J Dananberg; S A Lattimer
Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage.
Diabetes/metabolism reviews 1993;9(3):189-217.
1993: Martin J Stevens; D N Henry; Thommey P Thomas; Paul D Killen; Douglas A Greene
Aldose reductase gene expression and osmotic dysregulation in cultured human retinal pigment epithelial cells.
The American journal of physiology 1993;265(3 Pt 1):E428-38.
1992: Thommey P Thomas; Sumer Pek
Diacylglycerol inhibits potassium-induced calcium influx and insulin release by a protein kinase-C-independent mechanism in HIT T-15 islet cells.
Endocrinology 1992;131(4):1985-92.
1991: James A Shayman; G D Deshmukh; S Mahdiyoun; Thommey P Thomas; D Wu; F S Barcelon; N S Radin
Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol.
The Journal of biological chemistry 1991;266(34):22968-74.
1991: J Kim; E H Rushovich; Thommey P Thomas; Tetsufumi Ueda; Bernard W Agranoff; D A Greene
Diminished specific activity of cytosolic protein kinase C in sciatic nerve of streptozocin-induced diabetic rats and its correction by dietary myo-inositol.
Diabetes 1991;40(11):1545-54.
1991: Thommey P Thomas; D B Martin; Sumer Pek
Dioctanoylglycerol regulation of cytosolic Ca2+ by protein kinase C-independent mechanism in HIT T-15 islet cells.
Diabetes 1991;40(5):621-7.
1989: Thommey P Thomas; T R Ellis; Sumer Pek
Insulin release in RINm5F cells and glyceraldehyde activation of protein kinase C.
Diabetes 1989;38(11):1371-6.
1988: A K Ho; Thommey P Thomas; C L Chik; W B Anderson; David Klein
Protein kinase C: subcellular redistribution by increased Ca2+ influx. Evidence that Ca2+-dependent subcellular redistribution of protein kinase C is involved in potentiation of beta-adrenergic stimulation of pineal cAMP and cGMP by K+ and A23187.
The Journal of biological chemistry 1988;263(19):9292-7.
1988: Thommey P Thomas; H S Talwar; Wayne B Anderson
Phorbol ester-mediated association of protein kinase C to the nuclear fraction in NIH 3T3 cells.
Cancer research 1988;48(7):1910-9.
1987: Thommey P Thomas; R Gopalakrishna; W B Anderson
Hormone- and tumor promoter-induced activation or membrane association of protein kinase C in intact cells.
Methods in enzymology 1987;141():399-411.
1986: R Gopalakrishna; S H Barsky; Thommey P Thomas; W B Anderson
Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C.
The Journal of biological chemistry 1986;261(35):16438-45.
1986: M Taguchi; Thommey P Thomas; W B Anderson; W L Farrar
Direct phosphorylation of the IL-2 receptor Tac antigen epitope by protein kinase C.
Biochemical and biophysical research communications 1986;135(1):239-47.
1985: W L Farrar; Thommey P Thomas; W B Anderson
Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C.
Nature 1985;315(6016):235-7.
1985: D Sugden; J Vanecek; David Klein; Thommey P Thomas; W B Anderson
Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes.
Nature 1985;314(6009):359-61.
1983: Thommey P Thomas; G Philip
Purification & properties of glycogen phosphorylase a from mantle muscle of the cuttle fish, Sepia pharaonis.
Indian journal of biochemistry & biophysics 1983;20(4):198-202.
1983: Thommey P Thomas; G Philip
Control of glycogen phosphorylase from mantle muscle of the cuttle fish, Sepia pharaonis.
Indian journal of biochemistry & biophysics 1983;20(4):203-7.
1980: Thommey P Thomas; G Philip
Inhibition of rabbit muscle glycogen phosphorylase by aromatic compounds.
Indian journal of biochemistry & biophysics 1980;17(6):438-42.
1980: Thommey P Thomas; G Philip
Location of the aromatic binding site and preparation of an aromatic derivative of glycogen phosphorylase.
Biochimica et biophysica acta 1980;613(2):370-80.