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Craig Thompson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
28
Boise, Lawrence
24
June, Carl
22
Lindsten, Tullia
19
Turka, Laurence
18
Rathmell, Jeffrey
16
Leiden, Jeffrey
16
McCormack, Wayne
15
Vander Heiden, Matthew
13
Harris, Marian
13
Frauwirth, Kenneth
12
Zong, Wei-Xing
12
Rudin, Charles
12
Plas, David
11
Fox, Casey
10
Alegre, Maria-Luisa

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Publications

TOP 3
Kong Mei; Ditsworth Dara; Lindsten Tullia; Thompson Craig B
alpha4 is an essential regulator of PP2A phosphatase activity.
Thompson Craig B
Attacking cancer at its root.
Sabin Leah R; Zhou Rui; Gruber Joshua J; Lukinova Nina; Bambina Shelly; Berman Allison; Lau Chi-Kong; Thompson Craig B; Cherry Sara
Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.

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All Publications

2009: Kong Mei; Ditsworth Dara; Lindsten Tullia; Thompson Craig B
alpha4 is an essential regulator of PP2A phosphatase activity.
Molecular cell 2009;36(1):51-60.
2009: Thompson Craig B
Attacking cancer at its root.
Cell 2009;138(6):1051-4.
2009: Sabin Leah R; Zhou Rui; Gruber Joshua J; Lukinova Nina; Bambina Shelly; Berman Allison; Lau Chi-Kong; Thompson Craig B; Cherry Sara
Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.
Cell 2009;138(2):340-51.
2009: Gruber Joshua J; Zatechka D Steven; Sabin Leah R; Yong Jeongsik; Lum Julian J; Kong Mei; Zong Wei-Xing; Zhang Zhenxi; Lau Chi-Kong; Rawlings Jason; Cherry Sara; Ihle James N; Dreyfuss Gideon; Thompson Craig B
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.
Cell 2009;138(2):328-39.
2009: Wellen Kathryn E; Hatzivassiliou Georgia; Sachdeva Uma M; Bui Thi V; Cross Justin R; Thompson Craig B
ATP-citrate lyase links cellular metabolism to histone acetylation.
Science (New York, N.Y.) 2009;324(5930):1076-80.
2009: Thompson Craig B
Metabolic enzymes as oncogenes or tumor suppressors.
The New England journal of medicine 2009;360(8):813-5.
2009: Tong Xuemei; Zhao Fangping; Thompson Craig B
The molecular determinants of de novo nucleotide biosynthesis in cancer cells.
Current opinion in genetics & development 2009;19(1):32-7.
2008: Wise David R; DeBerardinis Ralph J; Mancuso Anthony; Sayed Nabil; Zhang Xiao-Yong; Pfeiffer Harla K; Nissim Ilana; Daikhin Evgueni; Yudkoff Marc; McMahon Steven B; Thompson Craig B
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(48):18782-7.
2008: Kundu Mondira; Lindsten Tullia; Yang Chia-Ying; Wu Junmin; Zhao Fangping; Zhang Ji; Selak Mary A; Ney Paul A; Thompson Craig B
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.
Blood 2008;112(4):1493-502.
2008: Sachdeva Uma M; Thompson Craig B
Diurnal rhythms of autophagy: implications for cell biology and human disease.
Autophagy 2008;4(5):581-9.
2008: Deberardinis Ralph J; Sayed Nabil; Ditsworth Dara; Thompson Craig B
Brick by brick: metabolism and tumor cell growth.
Current opinion in genetics & development 2008;18(1):54-61.
2008: DeBerardinis Ralph J; Lum Julian J; Hatzivassiliou Georgia; Thompson Craig B
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
Cell metabolism 2008;7(1):11-20.
2008: Woodland Robert T; Fox Casey J; Schmidt Madelyn R; Hammerman Peter S; Opferman Joseph T; Korsmeyer Stanley J; Hilbert David M; Thompson Craig B
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.
Blood 2008;111(2):750-60.
2008: Kundu Mondira; Thompson Craig B
Autophagy: basic principles and relevance to disease.
Annual review of pathology 2008;3():427-55.
2007: Amaravadi Ravi K; Thompson Craig B
The roles of therapy-induced autophagy and necrosis in cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(24):7271-9.
2007: DeBerardinis Ralph J; Mancuso Anthony; Daikhin Evgueni; Nissim Ilana; Yudkoff Marc; Wehrli Suzanne; Thompson Craig B
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19345-50.
2007: Kong Mei; Bui Thi V; Ditsworth Dara; Gruber Josh J; Goncharov Dmitry; Krymskaya Vera P; Lindsten Tullia; Thompson Craig B
The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration.
The Journal of biological chemistry 2007;282(40):29712-20.
2007: Jones Russell G; Thompson Craig B
Revving the engine: signal transduction fuels T cell activation.
Immunity 2007;27(2):173-8.
2007: Gordan John D; Thompson Craig B; Simon M Celeste
HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation.
Cancer cell 2007;12(2):108-13.
2007: Jones Russell G; Bui Thi; White Carl; Madesh Muniswamy; Krawczyk Connie M; Lindsten Tullia; Hawkins Brian J; Kubek Sara; Frauwirth Kenneth A; Wang Y Lynn; Conway Stuart J; Roderick H Llewelyn; Bootman Martin D; Shen Hao; Foskett J Kevin; Thompson Craig B
The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Immunity 2007;27(2):268-80.
2007: Buzzai Monica; Jones Russell G; Amaravadi Ravi K; Lum Julian J; DeBerardinis Ralph J; Zhao Fangping; Viollet Benoit; Thompson Craig B
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.
Cancer research 2007;67(14):6745-52.
2007: Ditsworth Dara; Zong Wei-Xing; Thompson Craig B
Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus.
The Journal of biological chemistry 2007;282(24):17845-54.
2007: Lum Julian J; Bui Thi; Gruber Michaela; Gordan John D; DeBerardinis Ralph J; Covello Kelly L; Simon M Celeste; Thompson Craig B
The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.
Genes & development 2007;21(9):1037-49.
2007: Amaravadi Ravi K; Yu Duonan; Lum Julian J; Bui Thi; Christophorou Maria A; Evan Gerard I; Thomas-Tikhonenko Andrei; Thompson Craig B
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma.
The Journal of clinical investigation 2007;117(2):326-36.
2006: Boxer Robert B; Stairs Douglas B; Dugan Katherine D; Notarfrancesco Kathleen L; Portocarrero Carla P; Keister Blaine A; Belka George K; Cho Han; Rathmell Jeffrey C; Thompson Craig B; Birnbaum Morris J; Chodosh Lewis A
Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.
Cell metabolism 2006;4(6):475-90.
2006: Deberardinis Ralph J; Lum Julian J; Thompson Craig B
Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth.
The Journal of biological chemistry 2006;281(49):37372-80.
2006: Lindsten T; Thompson C B
Cell death in the absence of Bax and Bak.
Cell death and differentiation 2006;13(8):1272-6.
2006: Bui Thi; Thompson Craig B
Cancer's sweet tooth.
Cancer cell 2006;9(6):419-20.
2006: Liu Liping; Cash Timothy P; Jones Russell G; Keith Brian; Thompson Craig B; Simon M Celeste
Hypoxia-induced energy stress regulates mRNA translation and cell growth.
Molecular cell 2006;21(4):521-31.
2006: Muthumani Karuppiah; Choo Andrew Y; Zong Wei-Xing; Madesh Muniswamy; Hwang Daniel S; Premkumar Arumugam; Thieu Khanh P; Emmanuel Joann; Kumar Sanjeev; Thompson Craig B; Weiner David B
The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1.
Nature cell biology 2006;8(2):170-9.
2005: Kundu M; Thompson C B
Macroautophagy versus mitochondrial autophagy: a question of fate?
Cell death and differentiation 2005;12 Suppl 2():1484-9.
2005: Fox Casey J; Hammerman Peter S; Thompson Craig B
Fuel feeds function: energy metabolism and the T-cell response.
Nature reviews. Immunology 2005;5(11):844-52.
2005: Parry Richard V; Chemnitz Jens M; Frauwirth Kenneth A; Lanfranco Anthony R; Braunstein Inbal; Kobayashi Sumire V; Linsley Peter S; Thompson Craig B; Riley James L
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.
Molecular and cellular biology 2005;25(21):9543-53.
2005: Hatzivassiliou Georgia; Zhao Fangping; Bauer Daniel E; Andreadis Charalambos; Shaw Anthony N; Dhanak Dashyant; Hingorani Sunil R; Tuveson David A; Thompson Craig B
ATP citrate lyase inhibition can suppress tumor cell growth.
Cancer cell 2005;8(4):311-21.
2005: Amaravadi Ravi; Thompson Craig B
The survival kinases Akt and Pim as potential pharmacological targets.
The Journal of clinical investigation 2005;115(10):2618-24.
2005: Bauer Daniel E; Hatzivassiliou Georgia; Zhao Fangping; Andreadis Charalambos; Thompson Craig B
ATP citrate lyase is an important component of cell growth and transformation.
Oncogene 2005;24(41):6314-22.
2005: Hahn Paul; Lindsten Tullia; Tolentino Michael; Thompson Craig B; Bennett Jean; Dunaief Joshua L
Persistent fetal ocular vasculature in mice deficient in bax and bak.
Archives of ophthalmology 2005;123(6):797-802.
2005: Lum Julian J; DeBerardinis Ralph J; Thompson Craig B
Autophagy in metazoans: cell survival in the land of plenty.
Nature reviews. Molecular cell biology 2005;6(6):439-48.
2005: Buzzai Monica; Bauer Daniel E; Jones Russell G; Deberardinis Ralph J; Hatzivassiliou Georgia; Elstrom Rebecca L; Thompson Craig B
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation.
Oncogene 2005;24(26):4165-73.
2005: Hammerman Peter S; Fox Casey J; Birnbaum Morris J; Thompson Craig B
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Blood 2005;105(11):4477-83.
2005: Jones Russell G; Plas David R; Kubek Sara; Buzzai Monica; Mu James; Xu Yang; Birnbaum Morris J; Thompson Craig B
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint.
Molecular cell 2005;18(3):283-93.
2005: Cinalli Ryan M; Herman Catherine E; Lew Brian O; Wieman Heather L; Thompson Craig B; Rathmell Jeffrey C
T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis.
European journal of immunology 2005;35(3):786-95.
2005: Lindsten Tullia; Zong Wei-Xing; Thompson Craig B
Defining the role of the Bcl-2 family of proteins in the nervous system.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2005;11(1):10-5.
2005: Lum Julian J; Bauer Daniel E; Kong Mei; Harris Marian H; Li Chi; Lindsten Tullia; Thompson Craig B
Growth factor regulation of autophagy and cell survival in the absence of apoptosis.
Cell 2005;120(2):237-48.
2005: Selak Mary A; Armour Sean M; MacKenzie Elaine D; Boulahbel Houda; Watson David G; Mansfield Kyle D; Pan Yi; Simon M Celeste; Thompson Craig B; Gottlieb Eyal
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.
Cancer cell 2005;7(1):77-85.
2005: Fox Casey J; Hammerman Peter S; Thompson Craig B
The Pim kinases control rapamycin-resistant T cell survival and activation.
The Journal of experimental medicine 2005;201(2):259-66.
2005: Thompson C B; Bauer D E; Lum J J; Hatzivassiliou G; Zong W-X; Zhao F; Ditsworth D; Buzzai M; Lindsten T
How do cancer cells acquire the fuel needed to support cell growth?
Cold Spring Harbor symposia on quantitative biology 2005;70():357-62.
2004: Edinger Aimee L; Thompson Craig B
Death by design: apoptosis, necrosis and autophagy.
Current opinion in cell biology 2004;16(6):663-9.
2004: Hammerman Peter S; Fox Casey J; Cinalli Ryan M; Xu Anne; Wagner John D; Lindsten Tullia; Thompson Craig B
Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation.
Cancer research 2004;64(22):8341-8.
2004: Hammerman Peter S; Fox Casey J; Thompson Craig B
Beginnings of a signal-transduction pathway for bioenergetic control of cell survival.
Trends in biochemical sciences 2004;29(11):586-92.
2004: Hahn P; Lindsten T; Lyubarsky A; Ying G-S; Pugh E N; Thompson C B; Dunaief J L
Deficiency of Bax and Bak protects photoreceptors from light damage in vivo.
Cell death and differentiation 2004;11(11):1192-7.
2004: Kong Mei; Fox Casey J; Mu James; Solt Laura; Xu Anne; Cinalli Ryan M; Birnbaum Morris J; Lindsten Tullia; Thompson Craig B
The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis.
Science (New York, N.Y.) 2004;306(5696):695-8.
2004: Thompson James E; Thompson Craig B
Putting the rap on Akt.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(20):4217-26.
2004: Bauer Daniel E; Harris Marian H; Plas David R; Lum Julian J; Hammerman Peter S; Rathmell Jeffrey C; Riley James L; Thompson Craig B
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1303-5.
2004: Edinger Aimee L; Thompson Craig B
An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival.
Oncogene 2004;23(33):5654-63.
2004: Elstrom Rebecca L; Bauer Daniel E; Buzzai Monica; Karnauskas Robyn; Harris Marian H; Plas David R; Zhuang Hongming; Cinalli Ryan M; Alavi Abass; Rudin Charles M; Thompson Craig B
Akt stimulates aerobic glycolysis in cancer cells.
Cancer research 2004;64(11):3892-9.
2004: Zong Wei-Xing; Ditsworth Dara; Bauer Daniel E; Wang Zhao-Qi; Thompson Craig B
Alkylating DNA damage stimulates a regulated form of necrotic cell death.
Genes & development 2004;18(11):1272-82.
2004: Arsham Andrew M; Plas David R; Thompson Craig B; Simon M Celeste
Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.
Cancer research 2004;64(10):3500-7.
2004: Bensinger Steven J; Walsh Patrick T; Zhang Jidong; Carroll Martin; Parsons Ramon; Rathmell Jeffrey C; Thompson Craig B; Burchill Matthew A; Farrar Michael A; Turka Laurence A
Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5287-96.
2004: Frauwirth Kenneth A; Thompson Craig B
Regulation of T lymphocyte metabolism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4661-5.
2004: Conejo-Garcia Jose R; Benencia Fabian; Courreges Maria C; Gimotty Phyllis A; Khang Eugene; Buckanovich Ronald J; Frauwirth Kenneth A; Zhang Lin; Katsaros Dionyssios; Thompson Craig B; Levine Bruce; Coukos George
Ovarian carcinoma expresses the NKG2D ligand Letal and promotes the survival and expansion of CD28- antitumor T cells.
Cancer research 2004;64(6):2175-82.
2003: Edinger Aimee L; Thompson Craig B
Defective autophagy leads to cancer.
Cancer cell 2003;4(6):422-4.
2003: Edinger Aimee L; Linardic Corinne M; Chiang Gary G; Thompson Craig B; Abraham Robert T
Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells.
Cancer research 2003;63(23):8451-60.
2003: Lindsten Tullia; Golden Jeffrey A; Zong Wei-Xing; Minarcik Jeremy; Harris Marian H; Thompson Craig B
The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(35):11112-9.
2003: Edinger Aimee L; Cinalli Ryan M; Thompson Craig B
Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression.
Developmental cell 2003;5(4):571-82.
2003: Rathmell Jeffrey C; Fox Casey J; Plas David R; Hammerman Peter S; Cinalli Ryan M; Thompson Craig B
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
Molecular and cellular biology 2003;23(20):7315-28.
2003: Carthy Christopher M; Yanagawa Bobby; Luo Honglin; Granville David J; Yang Decheng; Cheung Paul; Cheung Caroline; Esfandiarei Mitra; Rudin Charles M; Thompson Craig B; Hunt David W C; McManus Bruce M
Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection.
Virology 2003;313(1):147-57.
2003: Rathmell Jeffrey C; Elstrom Rebecca L; Cinalli Ryan M; Thompson Craig B
Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma.
European journal of immunology 2003;33(8):2223-32.
2003: Fox Casey J; Hammerman Peter S; Cinalli Ryan M; Master Stephen R; Chodosh Lewis A; Thompson Craig B
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor.
Genes & development 2003;17(15):1841-54.
2003: Conejo-Garcia Jose R; Benencia Fabian; Courreges Maria C; Khang Eugene; Zhang Lin; Mohamed-Hadley Alisha; Vinocur Jeffrey M; Buckanovich Ronald J; Thompson Craig B; Levine Bruce; Coukos George
Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells.
Cancer biology & therapy 2003;2(4):446-51.
2003: Zong Wei-Xing; Li Chi; Hatzivassiliou Georgia; Lindsten Tullia; Yu Qian-Chun; Yuan Junying; Thompson Craig B
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.
The Journal of cell biology 2003;162(1):59-69.
2003: Gottlieb E; Armour S M; Harris M H; Thompson C B
Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis.
Cell death and differentiation 2003;10(6):709-17.
2003: Plas David R; Thompson Craig B
Akt activation promotes degradation of tuberin and FOXO3a via the proteasome.
The Journal of biological chemistry 2003;278(14):12361-6.
2003: Gottlieb Eyal; Thompson Craig B
Targeting the mitochondria to enhance tumor suppression.
Methods in molecular biology (Clifton, N.J.) 2003;223():543-54.
2002: Li Chi; Thompson Craig B
Cancer. DNA damage, deamidation, and death.
Science (New York, N.Y.) 2002;298(5597):1346-7.
2002: Vander Heiden Matthew G; Choy John S; VanderWeele David J; Brace Jennifer L; Harris Marian H; Bauer Daniel E; Prange Bryan; Kron Stephen J; Thompson Craig B; Rudin Charles M
Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism.
The Journal of biological chemistry 2002;277(47):44870-6.
2002: Rathmell Jeffrey C; Lindsten Tullia; Zong Wei-Xing; Cinalli Ryan M; Thompson Craig B
Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.
Nature immunology 2002;3(10):932-9.
2002: Gottlieb Eyal; Armour Sean M; Thompson Craig B
Mitochondrial respiratory control is lost during growth factor deprivation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12801-6.
2002: Harlin Helena; Hwang Kwang Woo; Palucki David A; Kim Oliver; Thompson Craig B; Boothby Mark; Alegre Maria-Luisa
CTLA-4 engagement regulates NF-kappaB activation in vivo.
European journal of immunology 2002;32(8):2095-104.
2002: Talapatra S; Wagner J D O; Thompson C B
Elongation factor-1 alpha is a selective regulator of growth factor withdrawal and ER stress-induced apoptosis.
Cell death and differentiation 2002;9(8):856-61.
2002: Wang Y Lynn; Frauwirth Kenneth A; Rangwala Shamina M; Lazar Mitchell A; Thompson Craig B
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.
The Journal of biological chemistry 2002;277(35):31781-8.
2002: Edinger Aimee L; Thompson Craig B
Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake.
Molecular biology of the cell 2002;13(7):2276-88.
2002: Li Chi; Fox Casey J; Master Stephen R; Bindokas Vytautas P; Chodosh Lewis A; Thompson Craig B
Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9830-5.
2002: Frauwirth Kenneth A; Riley James L; Harris Marian H; Parry Richard V; Rathmell Jeffrey C; Plas David R; Elstrom Rebecca L; June Carl H; Thompson Craig B
The CD28 signaling pathway regulates glucose metabolism.
Immunity 2002;16(6):769-77.
2002: Plas David R; Rathmell Jeffrey C; Thompson Craig B
Homeostatic control of lymphocyte survival: potential origins and implications.
Nature immunology 2002;3(6):515-21.
2002: Rathmell Jeffrey C; Thompson Craig B
Pathways of apoptosis in lymphocyte development, homeostasis, and disease.
Cell 2002;109 Suppl():S97-107.
2002: Arsham Andrew M; Plas David R; Thompson Craig B; Simon M Celeste
Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription.
The Journal of biological chemistry 2002;277(17):15162-70.
2002: Plas David R; Thompson Craig B
Cell metabolism in the regulation of programmed cell death.
Trends in endocrinology and metabolism: TEM 2002;13(2):75-8.
2002: Edinger Aimee L; Thompson Craig B
Antigen-presenting cells control T cell proliferation by regulating amino acid availability.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1107-9.
2002: Frauwirth Kenneth A; Thompson Craig B
Activation and inhibition of lymphocytes by costimulation.
The Journal of clinical investigation 2002;109(3):295-9.
2001: Alegre M L; Frauwirth K A; Thompson C B
T-cell regulation by CD28 and CTLA-4.
Nature reviews. Immunology 2001;1(3):220-8.
2001: Rathmell J C; Farkash E A; Gao W; Thompson C B
IL-7 enhances the survival and maintains the size of naive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):6869-76.
2001: Frauwirth K A; Alegre M L; Thompson C B
CTLA-4 is not required for induction of CD8(+) T cell anergy in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):4936-41.
2001: Doyle A M; Mullen A C; Villarino A V; Hutchins A S; High F A; Lee H W; Thompson C B; Reiner S L
Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells.
The Journal of experimental medicine 2001;194(7):893-902.
2001: Talapatra S; Thompson C B
Growth factor signaling in cell survival: implications for cancer treatment.
The Journal of pharmacology and experimental therapeutics 2001;298(3):873-8.
2001: Vander Heiden M G; Plas D R; Rathmell J C; Fox C J; Harris M H; Thompson C B
Growth factors can influence cell growth and survival through effects on glucose metabolism.
Molecular and cellular biology 2001;21(17):5899-912.
2001: Zong W X; Lindsten T; Ross A J; MacGregor G R; Thompson C B
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak.
Genes & development 2001;15(12):1481-6.
2001: Vander Heiden M G; Li X X; Gottleib E; Hill R B; Thompson C B; Colombini M
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane.
The Journal of biological chemistry 2001;276(22):19414-9.
2001: Harlin H; Reffey S B; Duckett C S; Lindsten T; Thompson C B
Characterization of XIAP-deficient mice.
Molecular and cellular biology 2001;21(10):3604-8.
2001: Wei M C; Zong W X; Cheng E H; Lindsten T; Panoutsakopoulou V; Ross A J; Roth K A; MacGregor G R; Thompson C B; Korsmeyer S J
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.
Science (New York, N.Y.) 2001;292(5517):727-30.
2001: Plas D R; Talapatra S; Edinger A L; Rathmell J C; Thompson C B
Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology.
The Journal of biological chemistry 2001;276(15):12041-8.
2000: Harris M H; Thompson C B
The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability.
Cell death and differentiation 2000;7(12):1182-91.
2000: Lindsten T; Ross A J; King A; Zong W X; Rathmell J C; Shiels H A; Ulrich E; Waymire K G; Mahar P; Frauwirth K; Chen Y; Wei M; Eng V M; Adelman D M; Simon M C; Ma A; Golden J A; Evan G; Korsmeyer S J; MacGregor G R; Thompson C B
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Molecular cell 2000;6(6):1389-99.
2000: Rathmell J C; Vander Heiden M G; Harris M H; Frauwirth K A; Thompson C B
In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability.
Molecular cell 2000;6(3):683-92.
2000: Chuang E; Fisher T S; Morgan R W; Robbins M D; Duerr J M; Vander Heiden M G; Gardner J P; Hambor J E; Neveu M J; Thompson C B
The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.
Immunity 2000;13(3):313-22.
2000: Chandel N S; Vander Heiden M G; Thompson C B; Schumacker P T
Redox regulation of p53 during hypoxia.
Oncogene 2000;19(34):3840-8.
2000: Wei M C; Lindsten T; Mootha V K; Weiler S; Gross A; Ashiya M; Thompson C B; Korsmeyer S J
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.
Genes & development 2000;14(16):2060-71.
2000: Shiels H; Li X; Schumacker P T; Maltepe E; Padrid P A; Sperling A; Thompson C B; Lindsten T
TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs.
The American journal of pathology 2000;157(2):679-88.
2000: Gottlieb E; Vander Heiden M G; Thompson C B
Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis.
Molecular and cellular biology 2000;20(15):5680-9.
2000: Arch R H; Gedrich R W; Thompson C B
Translocation of TRAF proteins regulates apoptotic threshold of cells.
Biochemical and biophysical research communications 2000;272(3):936-45.
2000: Masteller E L; Chuang E; Mullen A C; Reiner S L; Thompson C B
Structural analysis of CTLA-4 function in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5319-27.
2000: Harris M H; Vander Heiden M G; Kron S J; Thompson C B
Role of oxidative phosphorylation in Bax toxicity.
Molecular and cellular biology 2000;20(10):3590-6.
2000: Vander Heiden M G; Chandel N S; Li X X; Schumacker P T; Colombini M; Thompson C B
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4666-71.
2000: Frauwirth K A; Alegre M L; Thompson C B
Induction of T cell anergy in the absence of CTLA-4/B7 interaction.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):2987-93.
2000: Zhou Y P; Pena J C; Roe M W; Mittal A; Levisetti M; Baldwin A C; Pugh W; Ostrega D; Ahmed N; Bindokas V P; Philipson L H; Hanahan D; Thompson C B; Polonsky K S
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.
American journal of physiology. Endocrinology and metabolism 2000;278(2):E340-51.
1999: Vander Heiden M G; Thompson C B
Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
Nature cell biology 1999;1(8):E209-16.
1999: Chang B S; Kelekar A; Harris M H; Harlan J E; Fesik S W; Thompson C B
The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L).
Molecular and cellular biology 1999;19(10):6673-81.
1999: Carthy C M; Granville D J; Jiang H; Levy J G; Rudin C M; Thompson C B; McManus B M; Hunt D W
Early release of mitochondrial cytochrome c and expression of mitochondrial epitope 7A6 with a porphyrin-derived photosensitizer: Bcl-2 and Bcl-xL overexpression do not prevent early mitochondrial events but still depress caspase activity.
Laboratory investigation; a journal of technical methods and pathology 1999;79(8):953-65.
1999: Pena J C; Kelekar A; Fuchs E V; Thompson C B
Manipulation of outer root sheath cell survival perturbs the hair-growth cycle.
The EMBO journal 1999;18(13):3596-603.
1999: Vander Heiden M G; Chandel N S; Schumacker P T; Thompson C B
Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange.
Molecular cell 1999;3(2):159-67.
1999: Chuang E; Lee K M; Robbins M D; Duerr J M; Alegre M L; Hambor J E; Neveu M J; Bluestone J A; Thompson C B
Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1270-7.
1999: Minn A J; Kettlun C S; Liang H; Kelekar A; Vander Heiden M G; Chang B S; Fesik S W; Fill M; Thompson C B
Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms.
The EMBO journal 1999;18(3):632-43.
1999: Pena J C; Thompson C B; Recant W; Vokes E E; Rudin C M
Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck.
Cancer 1999;85(1):164-70.
1999: Thompson C B; Rathmell J C; Frauwirth K A; Lindsten T; Rudin C M; Opferman J T; Ashton-Rickardt P G; Harris M H; Chandel N S; Schumacker P T; Vander Heiden M G
What keeps a resting T cell alive?
Cold Spring Harbor symposia on quantitative biology 1999;64():383-7.
1999: Arch R H; Thompson C B
Lymphocyte survival--the struggle against death.
Annual review of cell and developmental biology 1999;15():113-40.
1999: Rathmell J C; Thompson C B
The central effectors of cell death in the immune system.
Annual review of immunology 1999;17():781-828.
1998: Dragovich T; Rudin C M; Thompson C B
Signal transduction pathways that regulate cell survival and cell death.
Oncogene 1998;17(25):3207-13.
1998: Lee K M; Chuang E; Griffin M; Khattri R; Hong D K; Zhang W; Straus D; Samelson L E; Thompson C B; Bluestone J A
Molecular basis of T cell inactivation by CTLA-4.
Science (New York, N.Y.) 1998;282(5397):2263-6.
1998: Alegre M L; Shiels H; Thompson C B; Gajewski T F
Expression and function of CTLA-4 in Th1 and Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3347-56.
1998: Arch R H; Gedrich R W; Thompson C B
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death.
Genes & development 1998;12(18):2821-30.
1998: Noel P J; Alegre M L; Reiner S L; Thompson C B
Impaired negative selection in CD28-deficient mice.
Cellular immunology 1998;187(2):131-8.
1998: Rudin C M; Thompson C B
B-cell development and maturation.
Seminars in oncology 1998;25(4):435-46.
1998: Kelekar A; Thompson C B
Bcl-2-family proteins: the role of the BH3 domain in apoptosis.
Trends in cell biology 1998;8(8):324-30.
1998: Lin H; Rathmell J C; Gray G S; Thompson C B; Leiden J M; Alegre M L
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.
The Journal of experimental medicine 1998;188(1):199-204.
1998: Dolan M E; Frydman B; Thompson C B; Diamond A M; Garbiras B J; Safa A R; Beck W T; Marton L J
Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents.
Anti-cancer drugs 1998;9(5):437-48.
1998: Funk P E; Thompson C B
Identification of a lectin that induces cell death in developing chicken B cells.
Cellular immunology 1998;186(1):75-81.
1998: Pena J C; Rudin C M; Thompson C B
A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas.
Cancer research 1998;58(10):2111-6.
1998: Markiewicz M A; Girao C; Opferman J T; Sun J; Hu Q; Agulnik A A; Bishop C E; Thompson C B; Ashton-Rickardt P G
Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3065-70.
1998: Stack R M; Thompson C B; Fitch F W
IL-4 enhances long-term survival of CD28-deficient T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2255-62.
1998: Gilfillan M C; Noel P J; Podack E R; Reiner S L; Thompson C B
Expression of the costimulatory receptor CD30 is regulated by both CD28 and cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2180-7.
1998: Michael N; Accavitti M A; Masteller E; Thompson C B
The antigen-binding characteristics of mAbs derived from in vivo priming of avian B cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1166-71.
1998: Duckett C S; Li F; Wang Y; Tomaselli K J; Thompson C B; Armstrong R C
Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c.
Molecular and cellular biology 1998;18(1):608-15.
1998: Arch R H; Thompson C B
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB.
Molecular and cellular biology 1998;18(1):558-65.
1997: Kelekar A; Chang B S; Harlan J E; Fesik S W; Thompson C B
Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.
Molecular and cellular biology 1997;17(12):7040-6.
1997: Vander Heiden M G; Chandel N S; Williamson E K; Schumacker P T; Thompson C B
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria.
Cell 1997;91(5):627-37.
1997: Duckett C S; Thompson C B
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival.
Genes & development 1997;11(21):2810-21.
1997: Thompson C B; Allison J P
The emerging role of CTLA-4 as an immune attenuator.
Immunity 1997;7(4):445-50.
1997: Funk P E; Tregaskes C A; Young J R; Thompson C B
The avian chB6 (Bu-1) alloantigen can mediate rapid cell death.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1695-702.
1997: Olopade O I; Adeyanju M O; Safa A R; Hagos F; Mick R; Thompson C B; Recant W M
Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases.
The cancer journal from Scientific American 1997;3(4):230-7.
1997: Chuang E; Alegre M L; Duckett C S; Noel P J; Vander Heiden M G; Thompson C B
Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):144-51.
1997: Duckett C S; Thompson C B
The control and execution of programmed cell death: an update.
Biochimica et biophysica acta 1997;1332(3):R45-7.
1997: Pena J C; Fuchs E; Thompson C B
Bcl-x expression influences keratinocyte cell survival but not terminal differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(6):619-29.
1997: Boise L H; Thompson C B
Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3759-64.
1997: Chang B S; Minn A J; Muchmore S W; Fesik S W; Thompson C B
Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.
The EMBO journal 1997;16(5):968-77.
1997: Duckett C S; Gedrich R W; Gilfillan M C; Thompson C B
Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2.
Molecular and cellular biology 1997;17(3):1535-42.
1997: Minn A J; Vélez P; Schendel S L; Liang H; Muchmore S W; Fesik S W; Fill M; Thompson C B
Bcl-x(L) forms an ion channel in synthetic lipid membranes.
Nature 1997;385(6614):353-7.
1997: Masteller E L; Pharr G T; Funk P E; Thompson C B
Avian B cell development.
International reviews of immunology 1997;15(3-4):185-206.
1997: Rudin C M; Thompson C B
Apoptosis and disease: regulation and clinical relevance of programmed cell death.
Annual review of medicine 1997;48():267-81.
1996: Dole M G; Clarke M F; Holman P; Benedict M; Lu J; Jasty R; Eipers P; Thompson C B; Rode C; Bloch C; Nuñez; Castle V P
Bcl-xS enhances adenoviral vector-induced apoptosis in neuroblastoma cells.
Cancer research 1996;56(24):5734-40.
1996: Lee K P; Carlson L M; Woodcock J B; Ramachandra N; Schultz T L; Davis T A; Lowe J B; Thompson C B; Larsen R D
Molecular cloning and characterization of CFT1, a developmentally regulated avian alpha(1,3)-fucosyltransferase gene.
The Journal of biological chemistry 1996;271(51):32960-7.
1996: Alegre M L; Noel P J; Eisfelder B J; Chuang E; Clark M R; Reiner S L; Thompson C B
Regulation of surface and intracellular expression of CTLA4 on mouse T cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4762-70.
1996: Gajewski T F; Thompson C B
Apoptosis meets signal transduction: elimination of a BAD influence.
Cell 1996;87(4):589-92.
1996: Sperling A I; Auger J A; Ehst B D; Rulifson I C; Thompson C B; Bluestone J A
CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):3909-17.
1996: Eves E M; Boise L H; Thompson C B; Wagner A J; Hay N; Rosner M R
Apoptosis induced by differentiation or serum deprivation in an immortalized central nervous system neuronal cell line.
Journal of neurochemistry 1996;67(5):1908-20.
1996: Minn A J; Boise L H; Thompson C B
Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage.
Genes & development 1996;10(20):2621-31.
1996: Boise L H; Thompson C B
Hierarchical control of lymphocyte survival.
Science (New York, N.Y.) 1996;274(5284):67-8.
1996: Brown D R; Green J M; Moskowitz N H; Davis M; Thompson C B; Reiner S L
Limited role of CD28-mediated signals in T helper subset differentiation.
The Journal of experimental medicine 1996;184(3):803-10.
1996: Lenschow D J; Herold K C; Rhee L; Patel B; Koons A; Qin H Y; Fuchs E; Singh B; Thompson C B; Bluestone J A
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes.
Immunity 1996;5(3):285-93.
1996: Foreman K E; Wrone-Smith T; Boise L H; Thompson C B; Polverini P J; Simonian P L; Nunez G; Nickoloff B J
Kaposi's sarcoma tumor cells preferentially express Bcl-xL.
The American journal of pathology 1996;149(3):795-803.
1996: Noel P J; Boise L H; Green J M; Thompson C B
CD28 costimulation prevents cell death during primary T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):636-42.
1996: Green J M; Thompson C B
Homotypic interactions mediated through LFA-1/ICAM-3 decrease the proliferative response of activated T cells.
Cellular immunology 1996;171(1):126-31.
1996: Duckett C S; Nava V E; Gedrich R W; Clem R J; Van Dongen J L; Gilfillan M C; Shiels H; Hardwick J M; Thompson C B
A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.
The EMBO journal 1996;15(11):2685-94.
1996: Ferguson S E; Han S; Kelsoe G; Thompson C B
CD28 is required for germinal center formation.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4576-81.
1996: Muchmore S W; Sattler M; Liang H; Meadows R P; Harlan J E; Yoon H S; Nettesheim D; Chang B S; Thompson C B; Wong S L; Ng S L; Fesik S W
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature 1996;381(6580):335-41.
1996: Boise L H; McShan C L; Thompson C B
Introduction of the cell survival gene bcl-xL improves the viability of CTLL-2 cells without affecting their IL-2 proliferative response. Implications for the development of bioassays.
Journal of immunological methods 1996;191(2):143-8.
1996: Gedrich R W; Gilfillan M C; Duckett C S; Van Dongen J L; Thompson C B
CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins.
The Journal of biological chemistry 1996;271(22):12852-8.
1996: Minn A J; Boise L H; Thompson C B
Bcl-x(S) anatagonizes the protective effects of Bcl-x(L).
The Journal of biological chemistry 1996;271(11):6306-12.
1996: Prehn J H; Bindokas V P; Jordán J; Galindo M F; Ghadge G D; Roos R P; Boise L H; Thompson C B; Krajewski S; Reed J C; Miller R J
Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons.
Molecular pharmacology 1996;49(2):319-28.
1996: Grillot D A; Merino R; Pena J C; Fanslow W C; Finkelman F D; Thompson C B; Nunez G
bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.
The Journal of experimental medicine 1996;183(2):381-91.
1996: Walunas T L; Sperling A I; Khattri R; Thompson C B; Bluestone J A
CD28 expression is not essential for positive and negative selection of thymocytes or peripheral T cell tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1006-13.
1996: Gottschalk A R; Boise L H; Oltvai Z N; Accavitti M A; Korsmeyer S J; Quintáns J; Thompson C B
The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated.
Cell death and differentiation 1996;3(1):113-8.
1996: Rudin C M; Van Dongen J; Thompson C B
Apoptotic signaling in lymphocytes.
Current opinion in hematology 1996;3(1):35-40.
1996: Funk P E; Thompson C B
Current concepts in chicken B cell development.
Current topics in microbiology and immunology 1996;212():17-28.
1996: Noel P J; Boise L H; Thompson C B
Regulation of T cell activation by CD28 and CTLA4.
Advances in experimental medicine and biology 1996;406():209-17.
1995: Masteller E L; Lee K P; Carlson L M; Thompson C B
Expression of sialyl Lewis(x) and Lewis(x) defines distinct stages of chicken B cell maturation.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(12):5550-6.
1995: Thompson C B
New insights into V(D)J recombination and its role in the evolution of the immune system.
Immunity 1995;3(5):531-9.
1995: Clarke M F; Apel I J; Benedict M A; Eipers P G; Sumantran V; González-García M; Doedens M; Fukunaga N; Davidson B; Dick J E; Minn A J; Boise L H; Thompson C B; Wicha M; Núñez G
A recombinant bcl-x s adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):11024-8.
1995: Boise L H; Noel P J; Thompson C B
CD28 and apoptosis.
Current opinion in immunology 1995;7(5):620-5.
1995: Minn A J; Rudin C M; Boise L H; Thompson C B
Expression of bcl-xL can confer a multidrug resistance phenotype.
Blood 1995;86(5):1903-10.
1995: Chao D T; Linette G P; Boise L H; White L S; Thompson C B; Korsmeyer S J
Bcl-XL and Bcl-2 repress a common pathway of cell death.
The Journal of experimental medicine 1995;182(3):821-8.
1995: Boise L H; Minn A J; Thompson C B
Receptors that regulate T-cell susceptibility to apoptotic cell death.
Annals of the New York Academy of Sciences 1995;766():70-80.
1995: Sedlak T W; Oltvai Z N; Yang E; Wang K; Boise L H; Thompson C B; Korsmeyer S J
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7834-8.
1995: Sperling A I; Green J M; Mosley R L; Smith P L; DiPaolo R J; Klein J R; Bluestone J A; Thompson C B
CD43 is a murine T cell costimulatory receptor that functions independently of CD28.
The Journal of experimental medicine 1995;182(1):139-46.
1995: Boise L H; Minn A J; Noel P J; June C H; Accavitti M A; Lindsten T; Thompson C B
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.
Immunity 1995;3(1):87-98.
1995: Dole M G; Jasty R; Cooper M J; Thompson C B; Nuñez G; Castle V P
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis.
Cancer research 1995;55(12):2576-82.
1995: Boise L H; Minn A J; June C H; Lindsten T; Thompson C B
Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5491-5.
1995: Masteller E L; Larsen R D; Carlson L M; Pickel J M; Nickoloff B; Lowe J; Thompson C B; Lee K P
Chicken B cells undergo discrete developmental changes in surface carbohydrate structure that appear to play a role in directing lymphocyte migration during embryogenesis.
Development (Cambridge, England) 1995;121(6):1657-67.
1995: Thompson C B
Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
Cell 1995;81(7):979-82.
1995: González-García M; García I; Ding L; O'Shea S; Boise L H; Thompson C B; Núñez G
bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4304-8.
1995: Wrone-Smith T; Johnson T; Nelson B; Boise L H; Thompson C B; Núñez G; Nickoloff B J
Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo.
The American journal of pathology 1995;146(5):1079-88.
1995: Green J M; Noel P J; Sperling A I; Walunas T L; Lenschow D J; Stack R; Gray G S; Bluestone J A; Thompson C B
T cell costimulation through the CD28 receptor.
Proceedings of the Association of American Physicians 1995;107(1):41-6.
1995: Thompson C B
Apoptosis in the pathogenesis and treatment of disease.
Science (New York, N.Y.) 1995;267(5203):1456-62.
1995: Yang E; Zha J; Jockel J; Boise L H; Thompson C B; Korsmeyer S J
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.
Cell 1995;80(2):285-91.
1995: Boise L H; Gottschalk A R; Quintáns J; Thompson C B
Bcl-2 and Bcl-2-related proteins in apoptosis regulation.
Current topics in microbiology and immunology 1995;200():107-21.
1994: Liang H; Mao X; Olejniczak E T; Nettesheim D G; Yu L; Meadows R P; Thompson C B; Fesik S W
Solution structure of the ets domain of Fli-1 when bound to DNA.
Nature structural biology 1994;1(12):871-5.
1994: Liang H; Olejniczak E T; Mao X; Nettesheim D G; Yu L; Thompson C B; Fesik S W
The secondary structure of the ets domain of human Fli-1 resembles that of the helix-turn-helix DNA-binding motif of the Escherichia coli catabolite gene activator protein.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11655-9.
1994: Ferguson S E; Accavitti M A; Wang D D; Chen C L; Thompson C B
Regulation of RAG-2 protein expression in avian thymocytes.
Molecular and cellular biology 1994;14(11):7298-305.
1994: González-García M; Pérez-Ballestero R; Ding L; Duan L; Boise L H; Thompson C B; Núñez G
bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria.
Development (Cambridge, England) 1994;120(10):3033-42.
1994: Green J M; Noel P J; Sperling A I; Walunas T L; Gray G S; Bluestone J A; Thompson C B
Absence of B7-dependent responses in CD28-deficient mice.
Immunity 1994;1(6):501-8.
1994: Walunas T L; Lenschow D J; Bakker C Y; Linsley P S; Freeman G J; Green J M; Thompson C B; Bluestone J A
CTLA-4 can function as a negative regulator of T cell activation.
Immunity 1994;1(5):405-13.
1994: Masteller E L; Thompson C B
B cell development in the chicken.
Poultry science 1994;73(7):998-1011.
1994: June C H; Bluestone J A; Nadler L M; Thompson C B
The B7 and CD28 receptor families.
Immunology today 1994;15(7):321-31.
1994: Gottschalk A R; Boise L H; Thompson C B; Quintáns J
Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7350-4.
1994: Mao X; Miesfeldt S; Yang H; Leiden J M; Thompson C B
The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities.
The Journal of biological chemistry 1994;269(27):18216-22.
1994: Goodman R E; Nestle F; Naidu Y M; Green J M; Thompson C B; Nickoloff B J; Turka L A
Keratinocyte-derived T cell costimulation induces preferential production of IL-2 and IL-4 but not IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5189-98.
1994: Wang C Y; Bassuk A G; Boise L H; Thompson C B; Bravo R; Leiden J M
Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors.
Molecular and cellular biology 1994;14(2):1153-9.
1994: Dayton J S; Lindsten T; Thompson C B; Mitchell B S
Effects of human T lymphocyte activation on inosine monophosphate dehydrogenase expression.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):984-91.
1994: Katz D A; Theodorakis N G; Cleveland D W; Lindsten T; Thompson C B
AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm.
Nucleic acids research 1994;22(2):238-46.
1994: Green J M; Zheng X G; Shimizu Y; Thompson C B; Turka L A
T cell receptor stimulation, but not CD28 costimulation, is dependent on LFA-1-mediated events.
European journal of immunology 1994;24(1):265-72.
1994: June C H; Vandenberghe P; Thompson C B
The CD28 and CTLA-4 receptor family.
Chemical immunology 1994;59():62-90.
1994: Green J M; Thompson C B
Modulation of T cell proliferative response by accessory cell interactions.
Immunologic research 1994;13(4):234-43.
1993: Nestle F O; Zheng X G; Thompson C B; Turka L A; Nickoloff B J
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6535-45.
1993: Lin H; Bolling S F; Linsley P S; Wei R Q; Gordon D; Thompson C B; Turka L A
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.
The Journal of experimental medicine 1993;178(5):1801-6.
1993: Boise L H; González-García M; Postema C E; Ding L; Lindsten T; Turka L A; Mao X; Nuñez G; Thompson C B
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.
Cell 1993;74(4):597-608.
1993: McCormack W T; Liu M; Postema C; Thompson C B; Turka L A
Excision products of TCR V alpha recombination contain in-frame rearrangements: evidence for continued V(D)J recombination in TCR+ thymocytes.
International immunology 1993;5(7):801-4.
1993: Miesfeldt S; Kim S; Hanson C A; Bohjanen P R; Leiden J M; Crist W M; Carroll A J; Thompson C B
DNA fragments of altered electrophoretic mobility in leukemia samples can arise from double-strand DNA breaks at nuclease hypersensitive sites of active genes.
Cancer genetics and cytogenetics 1993;68(1):34-41.
1993: McCormack W T; Thompson C B
Special features of the development of the chicken humoral immune system.
Research in immunology 1993;144(6-7):467-75; discussion 475-6.
1993: Mitchell B S; Dayton J S; Turka L A; Thompson C B
IMP dehydrogenase inhibitors as immunomodulators.
Annals of the New York Academy of Sciences 1993;685():217-24.
1993: Grober J S; Bowen B L; Ebling H; Athey B; Thompson C B; Fox D A; Stoolman L M
Monocyte-endothelial adhesion in chronic rheumatoid arthritis. In situ detection of selectin and integrin-dependent interactions.
The Journal of clinical investigation 1993;91(6):2609-19.
1993: Wang C Y; Petryniak B; Thompson C B; Kaelin W G; Leiden J M
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein.
Science (New York, N.Y.) 1993;260(5112):1330-5.
1993: Boise L H; Petryniak B; Mao X; June C H; Wang C Y; Lindsten T; Bravo R; Kovary K; Leiden J M; Thompson C B
The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.
Molecular and cellular biology 1993;13(3):1911-9.
1993: Pandey A; Tjoelker L W; Thompson C B
Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joining.
The Journal of experimental medicine 1993;177(2):329-37.
1993: McCormack W T; Hurley E A; Thompson C B
Germ line maintenance of the pseudogene donor pool for somatic immunoglobulin gene conversion in chickens.
Molecular and cellular biology 1993;13(2):821-30.
1993: McCormack W T; Tjoelker L W; Thompson C B
Immunoglobulin gene diversification by gene conversion.
Progress in nucleic acid research and molecular biology 1993;45():27-45.
1992: Thompson C B
Creation of immunoglobulin diversity by intrachromosomal gene conversion.
Trends in genetics : TIG 1992;8(12):416-22.
1992: Green J M; Turka L A; June C H; Thompson C B
CD28 and staphylococcal enterotoxins synergize to induce MHC-independent T-cell proliferation.
Cellular immunology 1992;145(1):11-20.
1992: Leiden J M; Wang C Y; Petryniak B; Markovitz D M; Nabel G J; Thompson C B
A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells.
Journal of virology 1992;66(10):5890-7.
1992: Mao X; Green J M; Safer B; Lindsten T; Frederickson R M; Miyamoto S; Sonenberg N; Thompson C B
Regulation of translation initiation factor gene expression during human T cell activation.
The Journal of biological chemistry 1992;267(28):20444-50.
1992: Turka L A; Fletcher M C; Craighead N; Thompson C B; June C H
Defective signal transduction by the CD2 molecule in immature T-cell receptor/CD3- thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8706-10.
1992: Wang C Y; Petryniak B; Ho I C; Thompson C B; Leiden J M
Evolutionarily conserved Ets family members display distinct DNA binding specificities.
The Journal of experimental medicine 1992;175(5):1391-9.
1992: Dayton J S; Turka L A; Thompson C B; Mitchell B S
Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism.
Molecular pharmacology 1992;41(4):671-6.
1992: Vandenberghe P; Freeman G J; Nadler L M; Fletcher M C; Kamoun M; Turka L A; Ledbetter J A; Thompson C B; June C H
Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells.
The Journal of experimental medicine 1992;175(4):951-60.
1992: Thompson C B; Wang C Y; Ho I C; Bohjanen P R; Petryniak B; June C H; Miesfeldt S; Zhang L; Nabel G J; Karpinski B
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.
Molecular and cellular biology 1992;12(3):1043-53.
1992: Bohjanen P R; Petryniak B; June C H; Thompson C B; Lindsten T
AU RNA-binding factors differ in their binding specificities and affinities.
The Journal of biological chemistry 1992;267(9):6302-9.
1992: Turka L A; Kanner S B; Schieven G L; Thompson C B; Ledbetter J A
CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation.
European journal of immunology 1992;22(2):551-7.
1991: Lahti J M; Chen C L; Tjoelker L W; Pickel J M; Schat K A; Calnek B W; Thompson C B; Cooper M D
Two distinct alpha beta T-cell lineages can be distinguished by the differential usage of T-cell receptor V beta gene segments.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10956-60.
1991: McCormack W T; Tjoelker L W; Stella G; Postema C E; Thompson C B
Chicken T-cell receptor beta-chain diversity: an evolutionarily conserved D beta-encoded glycine turn within the hypervariable CDR3 domain.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7699-703.
1991: Turka L A; Schatz D G; Oettinger M A; Chun J J; Gorka C; Lee K; McCormack W T; Thompson C B
Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking.
Science (New York, N.Y.) 1991;253(5021):778-81.
1991: Bohjanen P R; Petryniak B; June C H; Thompson C B; Lindsten T
An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.
Molecular and cellular biology 1991;11(6):3288-95.
1991: Turka L A; Dayton J; Sinclair G; Thompson C B; Mitchell B S
Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine.
The Journal of clinical investigation 1991;87(3):940-8.
1991: Carlson L M; Oettinger M A; Schatz D G; Masteller E L; Hurley E A; McCormack W T; Baltimore D; Thompson C B
Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion.
Cell 1991;64(1):201-8.
1991: McCormack W T; Tjoelker L W; Thompson C B
Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion.
Annual review of immunology 1991;9():219-41.
1991: Dayton J S; Turka L A; Thompson C B; Mitchell B S
Guanine ribonucleotide depletion inhibits T cell activation.
Advances in experimental medicine and biology 1991;309B():293-6.
1990: Ho I C; Bhat N K; Gottschalk L R; Lindsten T; Thompson C B; Papas T S; Leiden J M
Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer.
Science (New York, N.Y.) 1990;250(4982):814-8.
1990: Tjoelker L W; Carlson L M; Lee K; Lahti J; McCormack W T; Leiden J M; Chen C L; Cooper M D; Thompson C B
Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):7856-60.
1990: Lee K P; Taylor C; Petryniak B; Turka L A; June C H; Thompson C B
The genomic organization of the CD28 gene. Implications for the regulation of CD28 mRNA expression and heterogeneity.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(1):344-52.
1990: June C H; Ledbetter J A; Linsley P S; Thompson C B
Role of the CD28 receptor in T-cell activation.
Immunology today 1990;11(6):211-6.
1990: Kim S; Humphries E H; Tjoelker L; Carlson L; Thompson C B
Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line.
Molecular and cellular biology 1990;10(6):3224-31.
1990: Bhat N K; Thompson C B; Lindsten T; June C H; Fujiwara S; Koizumi S; Fisher R J; Papas T S
Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3723-7.
1990: McCormack W T; Thompson C B
Chicken IgL variable region gene conversions display pseudogene donor preference and 5' to 3' polarity.
Genes & development 1990;4(4):548-58.
1990: Carlson L M; McCormack W T; Postema C E; Humphries E H; Thompson C B
Templated insertions in the rearranged chicken IgL V gene segment arise by intrachromosomal gene conversion.
Genes & development 1990;4(4):536-47.
1990: Turka L A; Ledbetter J A; Lee K; June C H; Thompson C B
CD28 is an inducible T cell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1646-53.
1990: Petryniak B; Staudt L M; Postema C E; McCormack W T; Thompson C B
Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1099-103.
1990: McCormack W T; Thompson C B
Somatic diversification of the chicken immunoglobulin light-chain gene.
Advances in immunology 1990;48():41-67.
1989: Guba S C; Stella G; Turka L A; June C H; Thompson C B; Emerson S G
Regulation of interleukin 3 gene induction in normal human T cells.
The Journal of clinical investigation 1989;84(6):1701-6.
1989: June C H; Ledbetter J A; Lindsten T; Thompson C B
Evidence for the involvement of three distinct signals in the induction of IL-2 gene expression in human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(1):153-61.
1989: Leiden J M; Yang L H; Morle G D; June C H; Lindsten T; Thompson C B; Karpinski B
The 4F2 heavy chain gene: a molecular model of inducible gene expression in human T cells.
Journal of autoimmunity 1989;2 Suppl():67-79.
1989: June C H; Jackson K M; Ledbetter J A; Leiden J M; Lindsten T; Thompson C B
Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes.
Journal of autoimmunity 1989;2 Suppl():55-65.
1989: McCormack W T; Tjoelker L W; Barth C F; Carlson L M; Petryniak B; Humphries E H; Thompson C B
Selection for B cells with productive IgL gene rearrangements occurs in the bursa of Fabricius during chicken embryonic development.
Genes & development 1989;3(6):838-47.
1989: Lindstein T; June C H; Ledbetter J A; Stella G; Thompson C B
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway.
Science (New York, N.Y.) 1989;244(4902):339-43.
1989: Parmacek M S; Karpinski B A; Gottesdiener K M; Thompson C B; Leiden J M
Structure, expression and regulation of the murine 4F2 heavy chain.
Nucleic acids research 1989;17(5):1915-31.
1989: McCormack W T; Tjoelker L W; Carlson L M; Petryniak B; Barth C F; Humphries E H; Thompson C B
Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments.
Cell 1989;56(5):785-91.
1989: Thompson C B; Lindsten T; Ledbetter J A; Kunkel S L; Young H A; Emerson S G; Leiden J M; June C H
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(4):1333-7.
1989: McCormack W T; Carlson L M; Tjoelker L W; Thompson C B
Evolutionary comparison of the avian IgL locus: combinatorial diversity plays a role in the generation of the antibody repertoire in some avian species.
International immunology 1989;1(4):332-41.
1988: Lindsten T; June C H; Thompson C B; Leiden J M
Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms.
Molecular and cellular biology 1988;8(9):3820-6.
1988: Gottesdiener K M; Karpinski B A; Lindsten T; Strominger J L; Jones N H; Thompson C B; Leiden J M
Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation.
Molecular and cellular biology 1988;8(9):3809-19.
1988: Lindsten T; June C H; Thompson C B
Transcription of T cell antigen receptor genes is induced by protein kinase C activation.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1769-74.
1988: Lindsten T; June C H; Thompson C B
Multiple mechanisms regulate c-myc gene expression during normal T cell activation.
The EMBO journal 1988;7(9):2787-94.
1988: Thompson C B; Jakubowski J A
The pathophysiology and clinical relevance of platelet heterogeneity.
Blood 1988;72(1):1-8.
1988: Neiman P E; Gehly E B; Carlson L M; Cotter R C; Thompson C B
Bursal stem cells as targets for myc-induced preneoplastic proliferation and maturation arrest.
Current topics in microbiology and immunology 1988;141():67-74.
1987: June C H; Ledbetter J A; Gillespie M M; Lindsten T; Thompson C B
T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression.
Molecular and cellular biology 1987;7(12):4472-81.
1987: Thompson C B; Humphries E H; Carlson L M; Chen C L; Neiman P E
The effect of alterations in myc gene expression on B cell development in the bursa of Fabricius.
Cell 1987;51(3):371-81.

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