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Carl Borrebaeck

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Henrik Johansson; Ann-Sofie Albrekt; Carl A K Borrebaeck; Malin Lindstedt
The GARD assay for assessment of chemical skin sensitizers.
Niclas Olsson; Stefan Wallin; Carl A K Borrebaeck; Peter James; Christer Wingren
Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties.
Anna Sandström; Ralf Segersvärd; Roland Andersson; Carl A K Borrebaeck; Mattias Löhr; Christer Wingren
Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures.

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All Publications

2013: Henrik Johansson; Ann-Sofie Albrekt; Carl A K Borrebaeck; Malin Lindstedt
The GARD assay for assessment of chemical skin sensitizers.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(3):1163-9.
2012: Niclas Olsson; Stefan Wallin; Carl A K Borrebaeck; Peter James; Christer Wingren
Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties.
Protein science : a publication of the Protein Society 2012;21(12):1897-910.
2012: Anna Sandström; Ralf Segersvärd; Roland Andersson; Carl A K Borrebaeck; Mattias Löhr; Christer Wingren
Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures.
Proteomics. Clinical applications 2012;6(9-10):486-96.
2012: Sissela Broos; Peter Ellmark; Linda C Sandin; Thomas H Tötterman; Takami Akagi; Mitsuru Akashi; Jenny Apel; Carl A K Borrebaeck; Malin Lindstedt
Synergistic augmentation of CD40-mediated activation of antigen-presenting cells by amphiphilic poly(γ-glutamic acid) nanoparticles.
Biomaterials 2012;33(26):6230-9.
2012: Carl A K Borrebaeck
Viewpoints in clinical proteomics: when will proteomics deliver clinically useful information?
Proteomics. Clinical applications 2012;6(7-8):343-5.
2012: Niclas Olsson; Carl A K Borrebaeck; Peter James; Christer Wingren
Quantitative proteomics targeting classes of motif-containing peptides using immunoaffinity-based mass spectrometry.
Molecular & cellular proteomics : MCP 2012;11(8):342-54.
2012: Malin Kristensson; Karolina Olsson; Gunnar Sturfelt; Carl A K Borrebaeck; Joyce Carlson; Björn Wullt; Christer Wingren
Design of recombinant antibody microarrays for urinary proteomics.
Proteomics. Clinical applications 2012;6(5-6):291-6.
2012: Christer Wingren; Roland Andersson; Anders Carlsson; Matthias Löhr; Anna Sandström; Ralf Segersvärd; Carl A K Borrebaeck
Identification of serum biomarker signatures associated with pancreatic cancer.
Cancer research 2012;72(10):2481-90.
2011: Paolo Conrotto; Ulrika Andréasson; Carl A K Borrebaeck; Venera Kuci; Sara Ek
Knock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo.
Molecular oncology 2011;5(6):527-37.
2011: Niclas Olsson; Christer Wingren; David O'Connell; Dolores J Cahill; Peter James; Mikael Mattsson; Fredrik Nilsson; Carl A K Borrebaeck
Proteomic analysis and discovery using affinity proteomics and mass spectrometry.
Molecular & cellular proteomics : MCP 2011;10(10):M110.003962.
2011: Anders Carlsson; Sara Ek; Mårten Fernö; Elin Gustavsson; Christian Ingvar; Helena Jernström; Malin Kristensson; Mattias Ohlsson; Håkan Olsson; Carsten Peterson; Carsten Rose; Christer Wingren; Carl A K Borrebaeck
Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14252-7.
2011: Kristina Magnusson; Sharon F McGee; Gerrit Meijer; Kirsha Naicker; Sanjay Navani; Darran P O'Connor; Elton Rexhepaj; Mathias Uhlén; Kenneth Wester; Anna Asplund; Eric Belt; Helgi Birgisson; Anders Bjartell; Carl A K Borrebaeck; Donal J Brennan; Meike de Wit; William M Gallagher; Bengt Glimelius; Jeroen Goos; Marcus Gry; Karin Jirström; Louis B Johnson; Olli-Pekka Kallioniemi; Caroline Kampf; Sami Kilpinen; Rut Klinger; Emma Lundberg; Fredrik Pontén
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
The American journal of surgical pathology 2011;35(7):937-48.
2011: Elin Gustavsson; Sophia Hober; Malin Kristensson; Jenny Ottosson; Johanna Steen; Mathias Uhlén; Christer Wingren; Cajsa Älgenäs; Sara Ek; Carl A K Borrebaeck
Surrogate antigens as targets for proteome-wide binder selection.
New biotechnology 2011;28(4):302-11.
2011: Anders Carlsson; Dirk M Wuttge; Johan Ingvarsson; Anders A Bengtsson; Gunnar Sturfelt; Carl A K Borrebaeck; Christer Wingren
Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays.
Molecular & cellular proteomics : MCP 2011;10(5):M110.005033.
2011: Linda Dexlin-Mellby; Anna Sandström; Linn Antberg; Jenny Gunnarsson; Stefan R Hansson; Carl A K Borrebaeck; Christer Wingren
Design of recombinant antibody microarrays for membrane protein profiling of cell lysates and tissue extracts.
Proteomics 2011;11(8):1550-4.
2011: Kristina Lundberg; Sissela Broos; Lennart Greiff; Carl A K Borrebaeck; Malin Lindstedt
Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells.
European journal of pharmacology 2011;651(1-3):197-204.
2011: Carl A K Borrebaeck; Christer Wingren
Recombinant antibodies for the generation of antibody arrays.
Methods in molecular biology (Clifton, N.J.) 2011;785():247-62.
2011: M Centlow; Christer Wingren; Carl A K Borrebaeck; M J Brownstein; Stefan R Hansson
Differential gene expression analysis of placentas with increased vascular resistance and pre-eclampsia using whole-genome microarrays.
Journal of pregnancy 2011;2011():472354.
2010: Linda Dexlin-Mellby; Anna Sandström; Magnus Centlow; Sara Nygren; Stefan R Hansson; Carl A K Borrebaeck; Christer Wingren
Tissue proteome profiling of preeclamptic placenta using recombinant antibody microarrays.
Proteomics. Clinical applications 2010;4(10-11):794-807.
2010: Kristina Lundberg; Lennart Greiff; Carl A K Borrebaeck; Malin Lindstedt
FcεRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis.
Human immunology 2010;71(10):931-3.
2010: Sissela Broos; Kristina Lundberg; Takami Akagi; Koji Kadowaki; Mitsuru Akashi; Lennart Greiff; Carl A K Borrebaeck; Malin Lindstedt
Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: Implications for specific immunotherapy.
Vaccine 2010;28(31):5075-85.
2010: Anders Carlsson; Oscar Persson; Johan Ingvarsson; Bengt Widegren; Leif Salford; Carl A K Borrebaeck; Christer Wingren
Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients.
Proteomics. Clinical applications 2010;4(6-7):591-602.
2010: Ulrika Andréasson; Patrik Edén; Carsten Peterson; Carl-Magnus Högerkorp; Mats Jerkeman; Niels Andersen; Mattias Berglund; Christer Sundström; Richard Rosenquist; Carl A K Borrebaeck; Sara Ek
Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples.
American journal of hematology 2010;85(6):418-25.
2010: Oscar Persson; Leif G Salford; Johan Fransson; Bengt Widegren; Carl A K Borrebaeck; Bo Holmqvist
Distribution, cellular localization, and therapeutic potential of the tumor-associated antigen Ku70/80 in glioblastoma multiforme.
Journal of neuro-oncology 2010;97(2):207-15.
2010: Norihiro Kobayashi; Hiroyuki Oyama; Yoshinori Kato; Junichi Goto; Eskil Söderlind; Carl A K Borrebaeck
Two-step in vitro antibody affinity maturation enables estradiol-17beta assays with more than 10-fold higher sensitivity.
Analytical chemistry 2010;82(3):1027-38.
2009: Ulrika Andréasson; Michael Dictor; Mats Jerkeman; Mattias Berglund; Christer Sundström; Johan Linderoth; Richard Rosenquist; Carl A K Borrebaeck; Sara Ek
Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells.
American journal of hematology 2009;84(12):803-8.
2009: Peter Ellmark; Sara Ghatnekar-Nilsson; André Meister; Harry Heinzelmann; Lars Montelius; Christer Wingren; Carl A K Borrebaeck
Attovial-based antibody nanoarrays.
Proteomics 2009;9(24):5406-13.
2009: Carl A K Borrebaeck; Christer Wingren
Design of high-density antibody microarrays for disease proteomics: key technological issues.
Journal of proteomics 2009;72(6):928-35.
2009: Donal J Brennan; Sara Ek; Emma Doyle; Thomas Drew; Michael Foley; Grainne Flannelly; Darran P O'Connor; William M Gallagher; Sami Kilpinen; Olli Kallioniemi; Karin Jirstrom; Colm O'Herlihy; Carl A K Borrebaeck
The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer.
European journal of cancer (Oxford, England : 1990) 2009;45(8):1510-7.
2009: Christer Wingren; Peter James; Carl A K Borrebaeck
Strategy for surveying the proteome using affinity proteomics and mass spectrometry.
Proteomics 2009;9(6):1511-7.
2009: Carl A K Borrebaeck; Christer Wingren
Transferring proteomic discoveries into clinical practice.
Expert review of proteomics 2009;6(1):11-3.
2009: Christer Wingren; Carl A K Borrebaeck
Antibody-based microarrays.
Methods in molecular biology (Clifton, N.J.) 2009;509():57-84.
2009: Kristina Larsson; Malin Lindstedt; Kristina Lundberg; Linda Dexlin; Christer Wingren; Magnus Korsgren; Lennart Greiff; Carl A K Borrebaeck
CD4+ T cells have a key instructive role in educating dendritic cells in allergy.
International archives of allergy and immunology 2009;149(1):1-15.
2008: Sylwia Sekula; Jeanette Fuchs; Susanne Weg-Remers; Peter Nagel; Stefan Schuppler; Joe Fragala; Nora Theilacker; Matthias Franzreb; Christer Wingren; Peter Ellmark; Carl A K Borrebaeck; Chad A Mirkin; Harald Fuchs; Steven Lenhert
Multiplexed lipid dip-pen nanolithography on subcellular scales for the templating of functional proteins and cell culture.
Small (Weinheim an der Bergstrasse, Germany) 2008;4(10):1785-93.
2008: Kristina Lundberg; Malin Lindstedt; Kristina Larsson; Linda Dexlin; Christer Wingren; Mats Ohlin; Lennart Greiff; Carl A K Borrebaeck
Augmented Phl p 5-specific Th2 response after exposure of dendritic cells to allergen in complex with specific IgE compared to IgG1 and IgG4.
Clinical immunology (Orlando, Fla.) 2008;128(3):358-65.
2008: Peter Ellmark; Carl-Magnus Högerkorp; Sara Ek; L Belov; M Berglund; Richard Rosenquist; Richard I Christopherson; Carl A K Borrebaeck
Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays.
Cancer letters 2008;265(1):98-106.
2008: Johan Ingvarsson; Christer Wingren; Anders Carlsson; Peter Ellmark; Britta Wahren; Gunnel Engström; Ulrika Harmenberg; Morten Krogh; Carsten Peterson; Carl A K Borrebaeck
Detection of pancreatic cancer using antibody microarray-based serum protein profiling.
Proteomics 2008;8(11):2211-9.
2008: Sisay A Abayneh; Peter Ellmark; Ulf Karlsson; Henrik Andersson; Carl A K Borrebaeck; Ingrid Karlsson; Eva Maria Fenyö
Sensitivity of HIV type 1 primary isolates to human anti-CD40 antibody-mediated suppression is related to coreceptor use.
AIDS research and human retroviruses 2008;24(3):447-52.
2008: Peter Ellmark; Henrik Andersson; Sisay Abayneh; Eva Maria Fenyö; Carl A K Borrebaeck
Identification of a strongly activating human anti-CD40 antibody that suppresses HIV type 1 infection.
AIDS research and human retroviruses 2008;24(3):367-73.
2008: Ulrika Andréasson; Sara Ek; Hartmut Merz; Richard Rosenquist; Niels Andersen; Mats Jerkeman; Michael Dictor; Carl A K Borrebaeck
B cell lymphomas express CX3CR1 a non-B cell lineage adhesion molecule.
Cancer letters 2008;259(2):138-45.
2008: Christer Wingren; Carl A K Borrebaeck
Antibody microarray analysis of directly labelled complex proteomes.
Current opinion in biotechnology 2008;19(1):55-61.
2008: Anders Carlsson; Christer Wingren; Johan Ingvarsson; Peter Ellmark; Bo Baldertorp; Mårten Fernö; Håkan Olsson; Carl A K Borrebaeck
Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays.
European journal of cancer (Oxford, England : 1990) 2008;44(3):472-80.
2008: Eva Ortega-Paino; Johan Fransson; Sara Ek; Carl A K Borrebaeck
Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference.
Blood 2008;111(3):1617-24.
2008: Sara Ek; Michael Dictor; Mats Jerkeman; Karin Jirström; Carl A K Borrebaeck
Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma.
Blood 2008;111(2):800-5.
2008: Linda Dexlin; Johan Ingvarsson; B Frendéus; Carl A K Borrebaeck; Christer Wingren
Design of recombinant antibody microarrays for cell surface membrane proteomics.
Journal of proteome research 2008;7(1):319-27.
2007: Christer Wingren; Carl A K Borrebaeck
Progress in miniaturization of protein arrays--a step closer to high-density nanoarrays.
Drug discovery today 2007;12(19-20):813-9.
2007: Carl A K Borrebaeck; Christer Wingren
High-throughput proteomics using antibody microarrays: an update.
Expert review of molecular diagnostics 2007;7(5):673-86.
2007: Christer Wingren; Johan Ingvarsson; Linda Dexlin; Dominika Szul; Carl A K Borrebaeck
Design of recombinant antibody microarrays for complex proteome analysis: choice of sample labeling-tag and solid support.
Proteomics 2007;7(17):3055-65.
2007: Johan Ingvarsson; Anette Larsson; Anders G Sjöholm; Lennart Truedsson; Bo Jansson; Carl A K Borrebaeck; Christer Wingren
Design of recombinant antibody microarrays for serum protein profiling: targeting of complement proteins.
Journal of proteome research 2007;6(9):3527-36.
2007: Sara Ghatnekar-Nilsson; Linda Dexlin; Christer Wingren; Lars Montelius; Carl A K Borrebaeck
Design of atto-vial based recombinant antibody arrays combined with a planar wave-guide detection system.
Proteomics 2007;7(4):540-7.
2006: Johan Fransson; Carl A K Borrebaeck
The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis.
International journal of cancer. Journal international du cancer 2006;119(10):2492-6.
2006: Carl-Magnus Högerkorp; Carl A K Borrebaeck
The human CD77- B cell population represents a heterogeneous subset of cells comprising centroblasts, centrocytes, and plasmablasts, prompting phenotypical revision.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4341-9.
2006: Ulrika Andréasson; Sabine Flicker; Malin Lindstedt; Rudolf Valenta; Lennart Greiff; Magnus Korsgren; Carl A K Borrebaeck; Mats Ohlin
The human IgE-encoding transcriptome to assess antibody repertoires and repertoire evolution.
Journal of molecular biology 2006;362(2):212-27.
2006: Peter Ellmark; Johan Ingvarsson; Anders Carlsson; B Samuel Lundin; Christer Wingren; Carl A K Borrebaeck
Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody microarrays.
Molecular & cellular proteomics : MCP 2006;5(9):1638-46.
2006: Carl A K Borrebaeck
Antibody microarray-based oncoproteomics.
Expert opinion on biological therapy 2006;6(8):833-8.
2006: Cornelia Steinhauer; Christer Wingren; Farid Khan; Mingyue He; Michael J Taussig; Carl A K Borrebaeck
Improved affinity coupling for antibody microarrays: engineering of double-(His)6-tagged single framework recombinant antibody fragments.
Proteomics 2006;6(15):4227-34.
2006: Johan Fransson; Ulla-Carin Tornberg; Carl A K Borrebaeck; Roland Carlsson; Björn Frendéus
Rapid induction of apoptosis in B-cell lymphoma by functionally isolated human antibodies.
International journal of cancer. Journal international du cancer 2006;119(2):349-58.
2006: Fredrik Karlsson; Ann-Christin Malmborg Hager; Carl A K Borrebaeck
Escherichia coli TolA tolerates multiple amino-acid substitutions as revealed by screening randomized variants for membrane integrity and phage receptor function.
FEMS microbiology letters 2006;259(1):81-8.
2006: Sara Ek; Ulrika Andréasson; Sophia Hober; Caroline Kampf; Fredrik Pontén; Mathias Uhlén; Hartmut Merz; Carl A K Borrebaeck
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Molecular & cellular proteomics : MCP 2006;5(6):1072-81.
2006: Sara Ek; Erik Björck; Carl-Magnus Högerkorp; Magnus Nordenskjöld; Anna Porwit-MacDonald; Carl A K Borrebaeck
Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival.
International journal of cancer. Journal international du cancer 2006;118(8):2092-7.
2006: Erwin L Roggen; Malin Lindstedt; Carl A K Borrebaeck; Geert R Verheyen
Interactions between dendritic cells and epithelial cells in allergic disease.
Toxicology letters 2006;162(1):71-82.
2006: Kristina Larsson; Malin Lindstedt; Carl A K Borrebaeck
Functional and transcriptional profiling of MUTZ-3, a myeloid cell line acting as a model for dendritic cells.
Immunology 2006;117(2):156-66.
2006: Christer Wingren; Carl A K Borrebaeck
Antibody microarrays: current status and key technological advances.
Omics : a journal of integrative biology 2006;10(3):411-27.
2006: Johan Ingvarsson; Malin Lindstedt; Carl A K Borrebaeck; Christer Wingren
One-step fractionation of complex proteomes enables detection of low abundant analytes using antibody-based microarrays.
Journal of proteome research 2006;5(1):170-6.
2005: Michiya Matsusaki; Kristina Larsson; Takani Akagi; Malin Lindstedt; Mitsuru Akashi; Carl A K Borrebaeck
Nanosphere induced gene expression in human dendritic cells.
Nano letters 2005;5(11):2168-73.
2005: Malin Lindstedt; Kristina Lundberg; Carl A K Borrebaeck
Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4839-46.
2005: Charlotte Larsson; Hanna Bramfeldt; Christer Wingren; Carl A K Borrebaeck; Fredrik Höök
Gravimetric antigen detection utilizing antibody-modified lipid bilayers.
Analytical biochemistry 2005;345(1):72-80.
2005: Cornelia Steinhauer; Anton Ressine; György Marko-Varga; Thomas Laurell; Carl A K Borrebaeck; Christer Wingren
Biocompatibility of surfaces for antibody microarrays: design of macroporous silicon substrates.
Analytical biochemistry 2005;341(2):204-13.
2005: Malin Lindstedt; Asa Schiött; Astrid Bengtsson; Kristina Larsson; Magnus Korsgren; Lennart Greiff; Carl A K Borrebaeck
Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals.
International immunology 2005;17(4):401-9.
2005: Christer Wingren; Cornelia Steinhauer; Johan Ingvarsson; Erik Persson; Katrin Larsson; Carl A K Borrebaeck
Microarrays based on affinity-tagged single-chain Fv antibodies: sensitive detection of analyte in complex proteomes.
Proteomics 2005;5(5):1281-91.
2005: Erik Björck; Sara Ek; Ola Landgren; Mats Jerkeman; Mats Ehinger; Magnus Björkholm; Carl A K Borrebaeck; Anna Porwit-MacDonald; Magnus Nordenskjöld
High expression of cyclin B1 predicts a favorable outcome in patients with follicular lymphoma.
Blood 2005;105(7):2908-15.
2005: Malin Lindstedt; Asa Schiött; C R Johnsen; Erwin L Roggen; Bengt Johansson-Lindbom; Carl A K Borrebaeck
Individuals with occupational allergy to detergent enzymes display a differential transcriptional regulation and cellular immune response.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(2):199-206.
2005: Sara Ek; Eva Ortega; Carl A K Borrebaeck
Transcriptional profiling and assessment of cell lines as in vitro models for mantle cell lymphoma.
Leukemia research 2005;29(2):205-13.
2005: Fredrik Karlsson; Ann-Christin Malmborg Hager; Ann-Sofie Albrekt; Carl A K Borrebaeck
Genome-wide comparison of phage M13-infected vs. uninfected Escherichia coli.
Canadian journal of microbiology 2005;51(1):29-35.
2004: Asa Schiött; Malin Lindstedt; Bengt Johansson-Lindbom; Erwin L Roggen; Carl A K Borrebaeck
CD27- CD4+ memory T cells define a differentiated memory population at both the functional and transcriptional levels.
Immunology 2004;113(3):363-70.
2004: Christer Wingren; Carl A K Borrebaeck
High-throughput proteomics using antibody microarrays.
Expert review of proteomics 2004;1(3):355-64.
2004: Peter Ellmark; Mats Ohlin; Carl A K Borrebaeck; Christina Furebring
A novel mammalian display system for the selection of protein-protein interactions by decoy receptor engagement.
Journal of molecular recognition : JMR 2004;17(4):316-22.
2004: Sara Ek; Erik Björck; Anna Porwit-MacDonald; Magnus Nordenskjöld; Carl A K Borrebaeck
Increased expression of Ki-67 in mantle cell lymphoma is associated with de-regulation of several cell cycle regulatory components, as identified by global gene expression analysis.
Haematologica 2004;89(6):686-95.
2004: Johan Fransson; Sara Ek; Peter Ellmark; Eskil Söderlind; Carl A K Borrebaeck; Christina Furebring
Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics.
Cancer letters 2004;208(2):235-42.
2003: Bengt Johansson-Lindbom; Sigurdur Ingvarsson; Carl A K Borrebaeck
Germinal centers regulate human Th2 development.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1657-66.
2003: Ann-Christin Malmborg Hager; Peter Ellmark; Carl A K Borrebaeck; Christina Furebring
Affinity and epitope profiling of mouse anti-CD40 monoclonal antibodies.
Scandinavian journal of immunology 2003;57(6):517-24.
2003: Sofia Svedhem; Indriati Pfeiffer; Charlotte Larsson; Christer Wingren; Carl A K Borrebaeck; Fredrik Höök
Patterns of DNA-labeled and scFv-antibody-carrying lipid vesicles directed by material-specific immobilization of DNA and supported lipid bilayer formation on an Au/SiO2 template.
Chembiochem : a European journal of chemical biology 2003;4(4):339-43.
2003: Christer Wingren; Allen B Edmundson; Carl A K Borrebaeck
Designing proteins to crystallize through beta-strand pairing.
Protein engineering 2003;16(4):255-64.
2003: Fredrik Karlsson; Carl A K Borrebaeck; Nina Nilsson; Ann-Christin Malmborg Hager
The mechanism of bacterial infection by filamentous phages involves molecular interactions between TolA and phage protein 3 domains.
Journal of bacteriology 2003;185(8):2628-34.
2003: Peter Ellmark; Christina Furebring; Carl A K Borrebaeck
Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of mouse B cells from anti-immunoglobulin M-induced apoptosis.
Immunology 2003;108(4):452-7.
2003: Malin Lindstedt; Bengt Johansson-Lindbom; Carl A K Borrebaeck
Expression of CD137 (4-1BB) on human follicular dendritic cells.
Scandinavian journal of immunology 2003;57(4):305-10.
2003: Carl-Magnus Högerkorp; Sven Bilke; Thomas Breslin; Sigurdur Ingvarsson; Carl A K Borrebaeck
CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays.
Blood 2003;101(6):2307-13.
2003: Christer Wingren; Johan Ingvarsson; Malin Lindstedt; Carl A K Borrebaeck
Recombinant antibody microarrays--a viable option?
Nature biotechnology 2003;21(3):223.
2002: Cornelia Steinhauer; Christer Wingren; Ann-Christin Malmborg Hager; Carl A K Borrebaeck
Single framework recombinant antibody fragments designed for protein chip applications.
BioTechniques 2002;Suppl():38-45.
2002: Carl A K Borrebaeck; Mats Ohlin
Antibody evolution beyond Nature.
Nature biotechnology 2002;20(12):1189-90.
2002: Malin Lindstedt; Bengt Johansson-Lindbom; Carl A K Borrebaeck
Global reprogramming of dendritic cells in response to a concerted action of inflammatory mediators.
International immunology 2002;14(10):1203-13.
2002: Sara Ek; Carl-Magnus Högerkorp; Michael Dictor; Mats Ehinger; Carl A K Borrebaeck
Mantle cell lymphomas express a distinct genetic signature affecting lymphocyte trafficking and growth regulation as compared with subpopulations of normal human B cells.
Cancer research 2002;62(15):4398-405.
2002: Peter Ellmark; Camilla Ottosson; Carl A K Borrebaeck; Ann-Christin Malmborg Hager; Christina Furebring
Modulation of the CD40-CD40 ligand interaction using human anti-CD40 single-chain antibody fragments obtained from the n-CoDeR phage display library.
Immunology 2002;106(4):456-63.
2002: Pernilla Jirholt; Carl A K Borrebaeck; Mats Ohlin
Antibody evolution from the centre to the periphery: applied to a human antibody fragment recognising the tumour-associated antigen mucin-1.
Journal of molecular biology 2002;318(2):407-16.
2002: Bengt Johansson-Lindbom; Carl A K Borrebaeck
Germinal center B cells constitute a predominant physiological source of IL-4: implication for Th2 development in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3165-72.
2002: Christina Furebring; Andrea Speckner; Michael Mach; Inger Sandlie; Lars Norderhaug; Carl A K Borrebaeck; Heléne Turesson; Mats Ohlin
Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region.
Molecular immunology 2002;38(11):833-40.
2002: A Akesson; Sigurdur Ingvarsson; Fredrik Karlsson; Laura Leyva; Miguel Blanca; S A Cuerden; J A Smith; J W Coleman; Carl A K Borrebaeck
Characterization of specific IgE response in vitro against protein and drug allergens using atopic and normal donors.
Allergy 2002;57(3):193-200.
2002: Nina Nilsson; Fredrik Karlsson; Jasna Rakonjac; Carl A K Borrebaeck
Selective infection of E. coli as a function of a specific molecular interaction.
Journal of molecular recognition : JMR 2002;15(1):27-32.
2001: K Brady; S Fitzgerald; Sigurdur Ingvarsson; Carl A K Borrebaeck; Paul N Moynagh
CD40 employs p38 MAP kinase in IgE isotype switching.
Biochemical and biophysical research communications 2001;289(1):276-81.
2001: E Soderlind; Roland Carlsson; Carl A K Borrebaeck; Mats Ohlin
The immune diversity in a test tube--non-immunised antibody libraries and functional variability in defined protein scaffolds.
Combinatorial chemistry & high throughput screening 2001;4(5):409-16.
2001: Pernilla Jirholt; L Strandberg; Bo Jansson; Elias Krambovitis; Eskil Söderlind; Carl A K Borrebaeck; Roland Carlsson; L Danielsson; Mats Ohlin
A central core structure in an antibody variable domain determines antigen specificity.
Protein engineering 2001;14(1):67-74.
2000: K Dahlenborg; J D Pound; J Gordon; Carl A K Borrebaeck; Roland Carlsson
Signals sustaining human immunoglobulin V gene hypermutation in isolated germinal centre B cells.
Immunology 2000;101(2):210-7.
2000: A Akesson; Sigurdur Ingvarsson; K Brady; Paul N Moynagh; Carl A K Borrebaeck
Rapid polarization of Th2 cells during induction of antigen-specific IgE antibodies in vitro.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(9):1298-306.
2000: Eskil Söderlind; L Strandberg; Pernilla Jirholt; N Kobayashi; V Alexeiva; A M Aberg; A Nilsson; Bo Jansson; Mats Ohlin; Christer Wingren; L Danielsson; Roland Carlsson; Carl A K Borrebaeck
Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries.
Nature biotechnology 2000;18(8):852-6.
2000: Nina Nilsson; Ann-Christin Malmborg; Carl A K Borrebaeck
The phage infection process: a functional role for the distal linker region of bacteriophage protein 3.
Journal of virology 2000;74(9):4229-35.
2000: Nina Nilsson; Sigurdur Ingvarsson; Carl A K Borrebaeck
Immature B cells in bone marrow express Fas/FasL.
Scandinavian journal of immunology 2000;51(3):279-84.
2000: B Johansson; Sigurdur Ingvarsson; P Björck; Carl A K Borrebaeck
Human interdigitating dendritic cells induce isotype switching and IL-13-dependent IgM production in CD40-activated naive B cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1847-54.
1999: Sigurdur Ingvarsson; K Dahlenborg; Roland Carlsson; Carl A K Borrebaeck
Co-ligation of CD44 on naive human tonsillar B cells induces progression towards a germinal center phenotype.
International immunology 1999;11(5):739-44.
1999: T Andersson; Christina Furebring; Carl A K Borrebaeck; Sven Pettersson
Temporal expression of a V(H) promoter-Cmu transgene linked to the IgH HS1,2 enhancer.
Molecular immunology 1999;36(1):19-29.
1999: E Andersson; Paula Maria Henderikx; Elias Krambovitis; Hennie Hoogenboom; Carl A K Borrebaeck
A tandem repeat of MUC1 core protein induces a weak in vitro immune response in human B cells.
Cancer immunology, immunotherapy : CII 1999;47(5):249-56.
1998: Pernilla Jirholt; Mats Ohlin; Carl A K Borrebaeck; Eskil Söderlind
Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework.
Gene 1998;215(2):471-6.
1998: Mats Ohlin; Carl A K Borrebaeck
Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity.
Molecular immunology 1998;35(4):233-8.
1998: Allen B Edmundson; Carl A K Borrebaeck
Progress in programming antibody fragments to crystallize.
Immunotechnology : an international journal of immunological engineering 1998;3(4):309-17.
1998: C Faber; Lin Shan; Z Fan; Luke W Guddat; Christina Furebring; Mats Ohlin; Carl A K Borrebaeck; Allen B Edmundson
Three-dimensional structure of a human Fab with high affinity for tetanus toxoid.
Immunotechnology : an international journal of immunological engineering 1998;3(4):253-70.
1997: Ann-Christin Malmborg; Eskil Söderlind; L Frost; Carl A K Borrebaeck
Selective phage infection mediated by epitope expression on F pilus.
Journal of molecular biology 1997;273(3):544-51.
1997: N Kobayashi; Eskil Söderlind; Carl A K Borrebaeck
Analysis of assembly of synthetic antibody fragments: expression of functional scFv with predefined specificity.
BioTechniques 1997;23(3):500-3.
1997: M Wallén-Ohman; J W Larrick; Roland Carlsson; Carl A K Borrebaeck
Ligation of MHC class I induces apoptosis in human pre-B cell lines, in promyelocytic cell lines and in CD40-stimulated mature B cells.
International immunology 1997;9(4):599-606.
1997: Christina Furebring; Mats Ohlin; Sven Pettersson; Carl A K Borrebaeck
Evaluation of novel control elements by construction of eukaryotic expression vectors.
Gene 1997;188(2):191-8.
1997: Nina Nilsson; M Wallén-Ohman; Mats Ohlin; Carl A K Borrebaeck
Altered gene expression associated with apoptosis in a pre-B-leukemic cell line following cross-linking of MHC class I.
Experimental cell research 1997;231(1):190-7.
1997: K Dahlenborg; J D Pound; J Gordon; Carl A K Borrebaeck; Roland Carlsson
Terminal differentiation of human germinal center B cells in vitro.
Cellular immunology 1997;175(2):141-9.
1996: A C Malmborg; M Dueñas; Mats Ohlin; Eskil Söderlind; Carl A K Borrebaeck
Selection of binders from phage displayed antibody libraries using the BIAcore biosensor.
Journal of immunological methods 1996;198(1):51-7.
1996: M Dueñas; L T Chin; A C Malmborg; R Casalvilla; Mats Ohlin; Carl A K Borrebaeck
In vitro immunization of naive human B cells yields high affinity immunoglobulin G antibodies as illustrated by phage display.
Immunology 1996;89(1):1-7.
1996: P Ifversen; Carl A K Borrebaeck
SCID-hu-PBL: a model for making human antibodies?
Seminars in immunology 1996;8(4):243-8.
1996: Mats Ohlin; Carl A K Borrebaeck
Characteristics of human antibody repertoires following active immune responses in vivo.
Molecular immunology 1996;33(7-8):583-92.
1996: E Andersson; K Dahlenborg; Mats Ohlin; Carl A K Borrebaeck; Roland Carlsson
Immunoglobulin production induced by CD57+ GC-derived helper T cells in vitro requires addition of exogenous IL-2.
Cellular immunology 1996;169(2):166-73.
1996: Mats Ohlin; Carl A K Borrebaeck
Low affinity, antibody binding of an Escherichia coli-derived component.
FEMS immunology and medical microbiology 1996;13(2):161-8.
1996: M Dueñas; A C Malmborg; R Casalvilla; Mats Ohlin; Carl A K Borrebaeck
Selection of phage displayed antibodies based on kinetic constants.
Molecular immunology 1996;33(3):279-85.
1996: Mats Ohlin; H Owman; Michael Mach; Carl A K Borrebaeck
Light chain shuffling of a high affinity antibody results in a drift in epitope recognition.
Molecular immunology 1996;33(1):47-56.
1995: A C Malmborg; K Johansson; Mikael Sigvardsson; Carl A K Borrebaeck; Tomas Leanderson
Real-time analysis of Oct protein-octamer interaction and transcription complex assembly.
Molecular immunology 1995;32(17-18):1429-42.
1995: C Mårtensson; P Ifversen; Carl A K Borrebaeck; Roland Carlsson
Enhancement of specific immunoglobulin production in SCID-hu-PBL mice after in vitro priming of human B cells with superantigen.
Immunology 1995;86(2):224-30.
1995: J D Rioux; Bernard R Brodeur; Y Larose; Mats Ohlin; Carl A K Borrebaeck; Marianna M Newkirk
Generation of diversity in a human anti-viral response.
Annals of the New York Academy of Sciences 1995;764():381-3.
1995: S Ingvarsson; A C Simonsson Lagerkvist; Roland Carlsson; Carl A K Borrebaeck
Stimulation of human peripheral lymphocytes via CD3 and soluble antigen abrogates specific antibody production by reducing memory B cell numbers.
Scandinavian journal of immunology 1995;42(3):331-6.
1995: Eskil Söderlind; M Vergeles; Carl A K Borrebaeck
Domain libraries: synthetic diversity for de novo design of antibody V-regions.
Gene 1995;160(2):269-72.
1995: E Andersson; Mats Ohlin; Carl A K Borrebaeck; Roland Carlsson
CD4+CD57+ T cells derived from peripheral blood do not support immunoglobulin production by B cells.
Cellular immunology 1995;163(2):245-53.
1995: A C Malmborg; Carl A K Borrebaeck
BIAcore as a tool in antibody engineering.
Journal of immunological methods 1995;183(1):7-13.
1995: M Dueñas; Marta Ayala; J Vázquez; Mats Ohlin; Eskil Söderlind; Carl A K Borrebaeck; Jorge V. Gavilondo
A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli.
Gene 1995;158(1):61-6.
1995: S Ingvarsson; A C Lagerkvist; C Mårtensson; U Granberg; P Ifversen; Carl A K Borrebaeck; Roland Carlsson
Antigen-specific activation of B cells in vitro after recruitment of T cell help with superantigen.
Immunotechnology : an international journal of immunological engineering 1995;1(1):29-39.
1995: Mats Ohlin; B Plachter; V A Sundqvist; P G Steenbakkers; Jaap Middeldorp; Carl A K Borrebaeck
Human antibody reactivity against the lower matrix protein (pp65) produced by cytomegalovirus.
Clinical and diagnostic laboratory immunology 1995;2(3):325-9.
1995: A C Lagerkvist; Christina Furebring; Carl A K Borrebaeck
Single, antigen-specific B cells used to generate Fab fragments using CD40-mediated amplification or direct PCR cloning.
BioTechniques 1995;18(5):862-9.
1995: L T Chin; A C Malmborg; K Kristensson; Jorma Hinkula; Britta Wahren; Carl A K Borrebaeck
Mimicking the humoral immune response in vitro results in antigen-specific isotype switching supported by specific autologous T helper cells: generation of human HIV-1-neutralizing IgG monoclonal antibodies from naive donors.
European journal of immunology 1995;25(3):657-63.
1995: M Dueñas; Carl A K Borrebaeck
Novel helper phage design: intergenic region affects the assembly of bacteriophages and the size of antibody libraries.
FEMS microbiology letters 1995;125(2-3):317-21.
1995: L T Chin; M Dueñas; M Levi; Jorma Hinkula; Britta Wahren; Carl A K Borrebaeck
Molecular characterization of a human anti-HIV 1 monoclonal antibody revealed a CD26-related motif in CDR2.
Immunology letters 1995;44(1):25-30.
1995: Eskil Söderlind; M Dueñas; Carl A K Borrebaeck
Chaperonins in phage display of antibody fragments.
Methods in molecular biology (Clifton, N.J.) 1995;51():343-53.
1995: P Ifversen; C Mårtensson; L Danielsson; C Ingvar; Roland Carlsson; Carl A K Borrebaeck
Induction of primary antigen-specific immune reponses in SCID-hu-PBL by coupled T-B epitopes.
Immunology 1995;84(1):111-6.
1994: L T Chin; P Ifversen; K Kristensson; Britta Wahren; Roland Carlsson; Carl A K Borrebaeck
Human Th0-type T helper-cell clone supports antigen-specific immunoglobulin production in scid/beige-hu mice.
Scandinavian journal of immunology 1994;40(5):529-34.
1994: C Mårtensson; K Kristensson; S Kalliomäki; Carl A K Borrebaeck; Roland Carlsson
Antigen-specific human immunoglobulin production in SCID mice transplanted with human peripheral lymphocytes is dependent on CD4+ CD45RO+ T cells.
Immunology 1994;83(2):171-9.
1994: M Dueñas; Carl A K Borrebaeck
Clonal selection and amplification of phage displayed antibodies by linking antigen recognition and phage replication.
Bio/technology (Nature Publishing Company) 1994;12(10):999-1002.
1994: Mats Ohlin; H Owman; J D Rioux; Marianna M Newkirk; Carl A K Borrebaeck
Restricted variable region gene usage and possible rheumatoid factor relationship among human monoclonal antibodies specific for the AD-1 epitope on cytomegalovirus glycoprotein B.
Molecular immunology 1994;31(13):983-91.
1994: M Wallén-Ohman; Carl A K Borrebaeck
A cell surface antigen (BAL) defined by a mouse monoclonal antibody inducing apoptosis in a human lymphocytic leukemia cell line.
International journal of cancer. Journal international du cancer 1994;57(4):544-52.
1994: Mats Ohlin; Carl A K Borrebaeck
Flow cytometric analysis of the stability of antibody production by human x human x mouse heterohybridoma subclones.
Journal of immunological methods 1994;170(1):75-82.
1994: K Kristensson; L Kristensen; Carl A K Borrebaeck; Roland Carlsson
Activation of human CD4+45RA+ T cells using B cells as accessory cells.
Immunology letters 1994;39(3):223-9.
1994: M Dueñas; J Vázquez; Marta Ayala; Eskil Söderlind; Mats Ohlin; L Pérez; Carl A K Borrebaeck; Jorge V. Gavilondo
Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins.
BioTechniques 1994;16(3):476-7, 480-3.
1994: L T Chin; Jorma Hinkula; M Levi; Mats Ohlin; Britta Wahren; Carl A K Borrebaeck
Site-directed primary in vitro immunization: production of HIV-1 neutralizing human monoclonal antibodies from lymphocytes obtained from seronegative donors.
Immunology 1994;81(3):428-34.
1993: M Wallén-Ohman; P Lönnbro; A Schön; Carl A K Borrebaeck
Antibody-induced apoptosis in a human leukemia cell line is energy dependent: thermochemical analysis of cellular metabolism.
Cancer letters 1993;75(2):103-9.
1993: P Ifversen; X M Zhang; Mats Ohlin; J Zeuthen; Carl A K Borrebaeck
Effect of cell-derived growth factors and cytokines on the clonal outgrowth of EBV-infected B cells and established lymphoblastoid cell lines.
Human antibodies and hybridomas 1993;4(3):115-23.
1993: M Ayala Avila; J Vazques; L Danielsson; M E Fernández de Cossío; Carl A K Borrebaeck
Sequence determination of variable region genes of two human monoclonal antibodies against Neisseria meningitidis.
Gene 1993;127(2):273-4.
1993: Eskil Söderlind; A C Lagerkvist; M Dueñas; A C Malmborg; Marta Ayala; L Danielsson; Carl A K Borrebaeck
Chaperonin assisted phage display of antibody fragments on filamentous bacteriophages.
Bio/technology (Nature Publishing Company) 1993;11(4):503-7.
1993: Mats Ohlin; V A Sundqvist; Michael Mach; Britta Wahren; Carl A K Borrebaeck
Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies.
Journal of virology 1993;67(2):703-10.
1992: Mats Ohlin; K Kristensson; Roland Carlsson; Carl A K Borrebaeck
Epstein-Barr virus-induced transformation of human B lymphocytes: the effect of L-leucyl-L-leucine methyl ester on inhibitory T cell populations.
Immunology letters 1992;34(3):221-8.
1992: Eskil Söderlind; A C Simonsson; Carl A K Borrebaeck
Phage display technology in antibody engineering: design of phagemid vectors and in vitro maturation systems.
Immunological reviews 1992;130():109-24.
1992: Mats Ohlin; Jorma Hinkula; P A Broliden; R Grunow; Carl A K Borrebaeck; Britta Wahren
Human MoAbs produced from normal, HIV-1-negative donors and specific for glycoprotein gp120 of the HIV-1 envelope.
Clinical and experimental immunology 1992;89(2):290-5.
1992: A C Malmborg; A Michaëlsson; Mats Ohlin; Bo Jansson; Carl A K Borrebaeck
Real time analysis of antibody-antigen reaction kinetics.
Scandinavian journal of immunology 1992;35(6):643-50.
1992: Carl A K Borrebaeck; A C Malmborg; Christina Furebring; A Michaelsson; S Ward; L Danielsson; Mats Ohlin
Kinetic analysis of recombinant antibody-antigen interactions: relation between structural domains and antigen binding.
Bio/technology (Nature Publishing Company) 1992;10(6):697-8.
1992: K Kristensson; Carl A K Borrebaeck; Roland Carlsson
Human CD4+ T cells expressing CD45RA acquire the lymphokine gene expression of CD45RO+ T-helper cells after activation in vitro.
Immunology 1992;76(1):103-9.
1992: Roland Carlsson; C Mårtensson; S Kalliomäki; Mats Ohlin; Carl A K Borrebaeck
Human peripheral blood lymphocytes transplanted into SCID mice constitute an in vivo culture system exhibiting several parameters found in a normal humoral immune response and are a source of immunocytes for the production of human monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1065-71.
1991: L Danielsson; Christina Furebring; Mats Ohlin; L Hultman; M Abrahamson; Roland Carlsson; Carl A K Borrebaeck
Human monoclonal antibodies with different fine specificity for digoxin derivatives: cloning of heavy and light chain variable region sequences.
Immunology 1991;74(1):50-4.
1991: A C Simonsson; J W Larrick; Carl A K Borrebaeck
In vitro immunization of human B lymphocytes. MAPPing of lymphokine specific mRNA and the effect of recombinant factors.
Human antibodies and hybridomas 1991;2(3):148-54.
1991: Mats Ohlin; V A Sundqvist; G Gilljam; U Rudén; F O Gombert; Britta Wahren; Carl A K Borrebaeck
Characterization of human monoclonal antibodies directed against the pp65-kD matrix antigen of human cytomegalovirus.
Clinical and experimental immunology 1991;84(3):508-14.
1990: S A Möller; S Birkelund; Carl A K Borrebaeck
A high-affinity human monoclonal IgM antibody reacting with multiple strains of Mycoplasma hominis.
Journal of clinical laboratory analysis 1990;4(5):390-5.
1989: Mats Ohlin; P A Broliden; L Danielsson; B Wahren; J Rosen; Mikael Jondal; Carl A K Borrebaeck
Human monoclonal antibodies against a recombinant HIV envelope antigen produced by primary in vitro immunization. Characterization and epitope mapping.
Immunology 1989;68(3):325-31.
1989: Mats Ohlin; L Danielsson; Roland Carlsson; Carl A K Borrebaeck
The effect of leucyl-leucine methyl ester on proliferation and Ig secretion of EBV-transformed human B lymphocytes.
Immunology 1989;66(4):485-90.
1985: Carl A K Borrebaeck; L Linsefors
Hormonal Regulation of the Lectin Biosynthesis in Callus Culture of the Phaseolus vulgaris Plant.
Plant physiology 1985;79(3):659-62.