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Niels Borregaard

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
39
Kjeldsen, Lars
29
Cowland, Jack
18
Lollike, Karsten
15
Sørensen, Ole
13
Theilgaard-Mönch, Kim
13
Johnsen, Anders
11
Udby, Lene
10
Sørensen, Ole
10
Calafat, Jero
6
Gombart, Adrian
5
Jacobsen, Lars
5
Bratt, T
5
Bainton, DF
5
Ralfkiaer, Elisabeth
4
Nielsen, Finn Cilius

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Publications

TOP 3
Alpízar-Alpízar Warner; Laerum Ole Didrik; Illemann Martin; Ramírez José A; Arias Adriana; Malespín-Bendaña Wendy; Ramírez Vanessa; Lund Leif R; Borregaard Niels; Nielsen Boye Schnack
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori.
Niemann Carsten U; Cowland Jack B; Ralfkiaer Elisabeth; Abrink Magnus; Pejler Gunnar; Borregaard Niels
Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.
Adams John S; Ren Songyang; Liu Philip T; Chun Rene F; Lagishetty Venu; Gombart Adrian F; Borregaard Niels; Modlin Robert L; Hewison Martin
Vitamin d-directed rheostatic regulation of monocyte antibacterial responses.

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All Publications

2009: Alpízar-Alpízar Warner; Laerum Ole Didrik; Illemann Martin; Ramírez José A; Arias Adriana; Malespín-Bendaña Wendy; Ramírez Vanessa; Lund Leif R; Borregaard Niels; Nielsen Boye Schnack
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori.
Virchows Archiv : an international journal of pathology 2009;455(3):225-33.
2009: Niemann Carsten U; Cowland Jack B; Ralfkiaer Elisabeth; Abrink Magnus; Pejler Gunnar; Borregaard Niels
Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.
European journal of cell biology 2009;88(8):473-9.
2009: Adams John S; Ren Songyang; Liu Philip T; Chun Rene F; Lagishetty Venu; Gombart Adrian F; Borregaard Niels; Modlin Robert L; Hewison Martin
Vitamin d-directed rheostatic regulation of monocyte antibacterial responses.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4289-95.
2009: Wagener Gebhard; Gubitosa Gina; Wang Shuang; Borregaard Niels; Kim Mihwa; Lee H Thomas
A comparison of urinary neutrophil gelatinase-associated lipocalin in patients undergoing on- versus off-pump coronary artery bypass graft surgery.
Journal of cardiothoracic and vascular anesthesia 2009;23(2):195-9.
2009: Nielsen Finn Cilius; Borregaard Niels
[Pharmacogenetics and tailored drug therapy]
Ugeskrift for laeger 2009;171(10):790-4.
2009: Gombart Adrian F; Bhan Ishir; Borregaard Niels; Tamez Hector; Camargo Carlos A; Koeffler H Phillip; Thadhani Ravi
Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(4):418-24.
2008: Wagener Gebhard; Gubitosa Gina; Wang Shuang; Borregaard Niels; Kim Mihwa; Lee H Thomas
Urinary neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008;52(3):425-33.
2008: Honoré Christian; Rørvig Sara; Munthe-Fog Lea; Hummelshøj Tina; Madsen Hans O; Borregaard Niels; Garred Peter
The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma.
Molecular immunology 2008;45(10):2782-9.
2008: Jacobsen Lars C; Sørensen Ole E; Cowland Jack B; Borregaard Niels; Theilgaard-Mönch Kim
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Journal of leukocyte biology 2008;83(5):1155-64.
2008: Sørensen Ole E; Borregaard Niels; Cole Alexander M
Antimicrobial peptides in innate immune responses.
Contributions to microbiology 2008;15():61-77.
2008: Wagener Gebhard; Gubitosa Gina; Wang Shuang; Borregaard Niels; Kim Mihwa; Lee H Thomas
Increased incidence of acute kidney injury with aprotinin use during cardiac surgery detected with urinary NGAL.
American journal of nephrology 2008;28(4):576-82.
2007: Niemann C U; Kjeldsen L; Ralfkiaer E; Jensen M K; Borregaard N
Serglycin proteoglycan in hematologic malignancies: a marker of acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(12):2406-10.
2007: Laine Mikael; Porola Pauliina; Udby Lene; Kjeldsen Lars; Cowland Jack B; Borregaard Niels; Hietanen Jarkko; Ståhle Mona; Pihakari Antti; Konttinen Yrjö T
Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome.
Arthritis and rheumatism 2007;56(8):2575-84.
2007: Borregaard Niels; Sørensen Ole E; Theilgaard-Mönch Kim
Neutrophil granules: a library of innate immunity proteins.
Trends in immunology 2007;28(8):340-5.
2007: Lim Ratana; Ahmed Nuzhat; Borregaard Niels; Riley Clyde; Wafai Razan; Thompson Erik W; Quinn Michael A; Rice Gregory E
Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition.
International journal of cancer. Journal international du cancer 2007;120(11):2426-34.
2007: Pass Malene Bjerregaard; Borregaard Niels; Cowland Jack Bernard
Derangement of transcription factor profiles during in vitro differentiation of HL60 and NB4 cells.
Leukemia research 2007;31(6):827-37.
2007: Frasch S Courtney; Zemski-Berry Karin; Murphy Robert C; Borregaard Niels; Henson Peter M; Bratton Donna L
Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6540-8.
2007: Niemann Carsten U; Abrink Magnus; Pejler Gunnar; Fischer Rikke L; Christensen Erik I; Knight Stefan D; Borregaard Niels
Neutrophil elastase depends on serglycin proteoglycan for localization in granules.
Blood 2007;109(10):4478-86.
2007: Jacobsen Lars C; Theilgaard-Mönch Kim; Christensen Erik I; Borregaard Niels
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Blood 2007;109(7):3084-7.
2007: Udby Lene; Borregaard Niels
Subcellular fractionation of human neutrophils and analysis of subcellular markers.
Methods in molecular biology (Clifton, N.J.) 2007;412():35-56.
2006: Poulsen Christian Bjørn; Borup Rehannah; Borregaard Niels; Nielsen Finn Cilius; Møller Michael Boe; Ralfkiaer Elisabeth
Prognostic significance of metallothionein in B-cell lymphomas.
Blood 2006;108(10):3514-9.
2006: Theilgaard-Mönch Kim; Jacobsen Lars C; Nielsen Marianne J; Rasmussen Thomas; Udby Lene; Gharib Maged; Arkwright Peter D; Gombart Adrian F; Calafat Jero; Moestrup Søren K; Porse Bo T; Borregaard Niels
Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.
Blood 2006;108(1):353-61.
2006: Cowland Jack B; Muta Tatsushi; Borregaard Niels
IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5559-66.
2006: Borregaard Niels; Cowland Jack B
Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2006;19(2):211-5.
2006: Borregaard Niels
[Centralization versus decentralization. Hematology]
Ugeskrift for laeger 2006;168(15):1551-2.
2006: Simonsen Anne C; Johansson Pär I; Conlan Maureen G; Jacquet Michele; Lin Jin-Sying; Junge Klaus; Lin Lily; Sørensen Henning; Borregaard Niels; Flament Jocelyne
Transfusion of 7-day-old amotosalen photochemically treated buffy-coat platelets to patients with thrombocytopenia: a pilot study.
Transfusion 2006;46(3):424-33.
2006: Wynn R F; Sood M; Theilgaard-Mönch K; Jones C J; Gombart A F; Gharib M; Koeffler H P; Borregaard N; Arkwright P D
Intractable diarrhoea of infancy caused by neutrophil specific granule deficiency and cured by stem cell transplantation.
Gut 2006;55(2):292-3.
2006: Seo Seong Jun; Ahn Ji-Young; Hong Chang-Kwun; Seo Eun-Young; Kye Kyung-Chae; Lee Woong-Hee; Lee Sang-Keun; Lim Jong-Soon; Hahn Myong-Joon; Kjeldsen Lars; Borregaard Niels; Kim Chang Deok; Park Jang-Kyu; Lee Jeung-Hoon
Expression of neutrophil gelatinase-associated lipocalin in skin epidermis.
The Journal of investigative dermatology 2006;126(2):510-2.
2006: Theilgaard-Mönch Kim; Porse Bo T; Borregaard Niels
Systems biology of neutrophil differentiation and immune response.
Current opinion in immunology 2006;18(1):54-60.
2005: Møller T; Borregaard N; Tvede M; Adamsen L
Patient education--a strategy for prevention of infections caused by permanent central venous catheters in patients with haematological malignancies: a randomized clinical trial.
The Journal of hospital infection 2005;61(4):330-41.
2005: Klausen Pia; Niemann Carsten U; Cowland Jack B; Krabbe Karen; Borregaard Niels
On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute response.
European journal of haematology 2005;75(4):332-40.
2005: Faurschou Mikkel; Kamp Søren; Cowland Jack B; Udby Lene; Johnsen Anders H; Calafat Jero; Winther Henrik; Borregaard Niels
Prodefensins are matrix proteins of specific granules in human neutrophils.
Journal of leukocyte biology 2005;78(3):785-93.
2005: Theilgaard-Mönch Kim; Jacobsen Lars C; Rasmussen Thomas; Niemann Carsten U; Udby Lene; Borup Rehannah; Gharib Maged; Arkwright Peter D; Gombart Adrian F; Calafat Jero; Porse Bo T; Borregaard Niels
Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.
Journal of leukocyte biology 2005;78(2):462-70.
2005: Gombart Adrian F; Borregaard Niels; Koeffler H Phillip
Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1067-77.
2005: Udby Lene; Lundwall Ake; Johnsen Anders H; Fernlund Per; Valtonen-André Camilla; Blom Anna M; Lilja Hans; Borregaard Niels; Kjeldsen Lars; Bjartell Anders
beta-Microseminoprotein binds CRISP-3 in human seminal plasma.
Biochemical and biophysical research communications 2005;333(2):555-61.
2005: Poulsen Christian Bjørn; Borup Rehannah; Nielsen Finn Cilius; Borregaard Niels; Hansen Mads; Grønbaek Kirsten; Møller Michael Boe; Ralfkiaer Elisabeth
Microarray-based classification of diffuse large B-cell lymphoma.
European journal of haematology 2005;74(6):453-65.
2005: Sorensen Ole E; Borregaard Niels
Cathelicidins--nature's attempt at combinatorial chemistry.
Combinatorial chemistry & high throughput screening 2005;8(3):273-80.
2005: Vijay-Kumar Matam; Gentsch Jon R; Kaiser William J; Borregaard Niels; Offermann Margaret K; Neish Andrew S; Gewirtz Andrew T
Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6322-31.
2005: Udby Lene; Bjartell Anders; Malm Johan; Egesten Arne; Lundwall Ake; Cowland Jack B; Borregaard Niels; Kjeldsen Lars
Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract.
Journal of andrology 2005;26(3):333-42.
2005: Heilborn Johan D; Nilsson Margareta Frohm; Jimenez Clara I Chamorro; Sandstedt Bengt; Borregaard Niels; Tham Emma; Sørensen Ole E; Weber Günther; Ståhle Mona
Antimicrobial protein hCAP18/LL-37 is highly expressed in breast cancer and is a putative growth factor for epithelial cells.
International journal of cancer. Journal international du cancer 2005;114(5):713-9.
2005: Borregaard Niels; Theilgaard-Mönch Kim; Cowland Jack B; Ståhle Mona; Sørensen Ole E
Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place.
Journal of leukocyte biology 2005;77(4):439-43.
2005: Theilgaard-Mönch Kim; Jacobsen Lars Christian; Borup Rehannah; Rasmussen Thomas; Bjerregaard Malene Digmann; Nielsen Finn Cilius; Cowland Jack Bernard; Borregaard Niels
The transcriptional program of terminal granulocytic differentiation.
Blood 2005;105(4):1785-96.
2005: Hvidberg Vibeke; Jacobsen Christian; Strong Roland K; Cowland Jack B; Moestrup Søren K; Borregaard Niels
The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake.
FEBS letters 2005;579(3):773-7.
2004: Udby Lene; Sørensen Ole E; Pass Jesper; Johnsen Anders H; Behrendt Niels; Borregaard Niels; Kjeldsen Lars
Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma.
Biochemistry 2004;43(40):12877-86.
2004: Niemann Carsten Utoft; Cowland Jack Bernard; Klausen Pia; Askaa Jon; Calafat Jero; Borregaard Niels
Localization of serglycin in human neutrophil granulocytes and their precursors.
Journal of leukocyte biology 2004;76(2):406-15.
2004: Theilgaard-Mönch Kim; Knudsen Steen; Follin Per; Borregaard Niels
The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7684-93.
2004: Stefanidakis Michael; Ruohtula Terhi; Borregaard Niels; Gahmberg Carl G; Koivunen Erkki
Intracellular and cell surface localization of a complex between alphaMbeta2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7060-8.
2004: Gardai Shyra J; Hildeman David A; Frankel Steve K; Whitlock Ben B; Frasch S Courtney; Borregaard Niels; Marrack Philippa; Bratton Donna L; Henson Peter M
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils.
The Journal of biological chemistry 2004;279(20):21085-95.
2004: Salier Jean-Philippe; Akerström Bo; Borregaard Niels; Flower Darren R
Lipocalins in bioscience: the first family gathering.
BioEssays : news and reviews in molecular, cellular and developmental biology 2004;26(4):456-8.
2004: Frasch S Courtney; Henson Peter M; Nagaosa Kaz; Fessler Michael B; Borregaard Niels; Bratton Donna L
Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils.
The Journal of biological chemistry 2004;279(17):17625-33.
2004: Klausen Pia; Bjerregaard Malene Digmann; Borregaard Niels; Cowland Jack Bernard
End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6.
Journal of leukocyte biology 2004;75(3):569-78.
2003: Nielsen Ole Haagen; Borregaard Niels
[Transplantation: ethics and stem cells]
Ugeskrift for laeger 2003;165(50):4823.
2003: Tjabringa G Sandra; Aarbiou Jamil; Ninaber Dennis K; Drijfhout Jan Wouter; Sørensen Ole E; Borregaard Niels; Rabe Klaus F; Hiemstra Pieter S
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6690-6.
2003: Cowland Jack B; Sørensen Ole E; Sehested Maxwell; Borregaard Niels
Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6630-9.
2003: Faurschou Mikkel; Borregaard Niels
Neutrophil granules and secretory vesicles in inflammation.
Microbes and infection / Institut Pasteur 2003;5(14):1317-27.
2003: Adamsen Lis; Midtgaard Julie; Rorth Mikael; Borregaard Niels; Andersen Christina; Quist Morten; Møller Tom; Zacho Morten; Madsen Jan K; Knutsen Lasse
Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2003;11(11):707-16.
2003: Cowland Jack B; Carter Daniel; Bjerregaard Malene D; Johnsen Anders H; Borregaard Niels; Lollike Karsten
Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils.
Journal of leukocyte biology 2003;74(3):379-88.
2003: Sørensen Ole E; Gram Lone; Johnsen Anders H; Andersson Emma; Bangsbøll Susanne; Tjabringa G Sandra; Hiemstra Pieter S; Malm Johan; Egesten Arne; Borregaard Niels
Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina.
The Journal of biological chemistry 2003;278(31):28540-6.
2003: Sørensen Ole E; Cowland Jack B; Theilgaard-Mönch Kim; Liu Lide; Ganz Tomas; Borregaard Niels
Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5583-9.
2003: Bjerregaard Malene Digmann; Jurlander Jesper; Klausen Pia; Borregaard Niels; Cowland Jack Bernard
The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow.
Blood 2003;101(11):4322-32.
2003: Heilborn Johan D; Nilsson Margareta Frohm; Kratz Gunnar; Weber Günther; Sørensen Ole; Borregaard Niels; Ståhle-Bäckdahl Mona
The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium.
The Journal of investigative dermatology 2003;120(3):379-89.
2003: Poulsen Christian Bjørn; Ralfkiaer Elisabeth Methner; Borregaard Niels; Grønboek Kirsten
[Molecular biology diagnostics: malignant lymphoid tumors in adults]
Ugeskrift for laeger 2003;165(9):901-5.
2003: Borregaard Niels
[Part time positions clinical work/research. A necessary piece in the overall situation]
Ugeskrift for laeger 2003;165(4):351-2.
2002: Mallbris Lotus; O'Brien Kevin P; Hulthén Anna; Sandstedt Bengt; Cowland Jack B; Borregaard Niels; Ståhle-Bäckdahl Mona
Neutrophil gelatinase-associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin.
Experimental dermatology 2002;11(6):584-91.
2002: Goetz David H; Holmes Margaret A; Borregaard Niels; Bluhm Martin E; Raymond Kenneth N; Strong Roland K
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition.
Molecular cell 2002;10(5):1033-43.
2002: Andersson E; Sørensen O E; Frohm B; Borregaard N; Egesten A; Malm J
Isolation of human cationic antimicrobial protein-18 from seminal plasma and its association with prostasomes.
Human reproduction (Oxford, England) 2002;17(10):2529-34.
2002: Udby Lene; Calafat Jero; Sørensen Ole E; Borregaard Niels; Kjeldsen Lars
Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils.
Journal of leukocyte biology 2002;72(3):462-9.
2002: Faurschou Mikkel; Sørensen Ole E; Johnsen Anders H; Askaa Jon; Borregaard Niels
Defensin-rich granules of human neutrophils: characterization of secretory properties.
Biochimica et biophysica acta 2002;1591(1-3):29-35.
2002: Lollike Karsten; Lindau Manfred; Calafat Jero; Borregaard Niels
Compound exocytosis of granules in human neutrophils.
Journal of leukocyte biology 2002;71(6):973-80.
2002: Udby Lene; Cowland Jack B; Johnsen Anders H; Sørensen Ole E; Borregaard Niels; Kjeldsen Lars
An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions.
Journal of immunological methods 2002;263(1-2):43-55.
2002: Degousee Norbert; Ghomashchi Farideh; Stefanski Eva; Singer Alan; Smart Brian P; Borregaard Niels; Reithmeier Reinhardt; Lindsay Thomas F; Lichtenberger Cornelia; Reinisch Walter; Lambeau Gerard; Arm Jonathan; Tischfield Jay; Gelb Michael H; Rubin Barry B
Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.
The Journal of biological chemistry 2002;277(7):5061-73.
2002: Mirinics Zeljka Korade; Calafat Jero; Udby Lene; Lovelock Josh; Kjeldsen Lars; Rothermund Kristi; Sisodia Sangram S; Borregaard Niels; Corey Seth J
Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules.
Blood cells, molecules & diseases 2002;28(1):28-38.
2002: Kruger Joshua M; Fukushima Takayasu; Cherepanov Vera; Borregaard Niels; Loeve Carola; Shek Christina; Sharma Kalpana; Tanswell A Keith; Chow Chung-Wai; Downey Gregory P
Protein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides.
The Journal of biological chemistry 2002;277(4):2620-8.
2001: Jia J; Borregaard N; Lollike K; Cygler M
Structure of Ca(2+)-loaded human grancalcin.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1843-9.
2001: Sørensen O E; Follin P; Johnsen A H; Calafat J; Tjabringa G S; Hiemstra P S; Borregaard N
Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3.
Blood 2001;97(12):3951-9.
2001: Theilgaard-Mönch K; Cowland J; Borregaard N
Profiling of gene expression in individual hematopoietic cells by global mRNA amplification and slot blot analysis.
Journal of immunological methods 2001;252(1-2):175-89.
2001: Lollike K; Johnsen A H; Durussel I; Borregaard N; Cox J A
Biochemical characterization of the penta-EF-hand protein grancalcin and identification of L-plastin as a binding partner.
The Journal of biological chemistry 2001;276(21):17762-9.
2001: Borregaard N; Theilgaard-Mönch K; Sørensen O E; Cowland J B
Regulation of human neutrophil granule protein expression.
Current opinion in hematology 2001;8(1):23-7.
2000: Kjeldsen L; Cowland J B; Borregaard N
Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse.
Biochimica et biophysica acta 2000;1482(1-2):272-83.
2000: Jia J; Han Q; Borregaard N; Lollike K; Cygler M
Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
Journal of molecular biology 2000;300(5):1271-81.
2000: Malm J; Sørensen O; Persson T; Frohm-Nilsson M; Johansson B; Bjartell A; Lilja H; Ståhle-Bäckdahl M; Borregaard N; Egesten A
The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa.
Infection and immunity 2000;68(7):4297-302.
2000: Goetz D H; Willie S T; Armen R S; Bratt T; Borregaard N; Strong R K
Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin.
Biochemistry 2000;39(8):1935-41.
1999: Sørensen O; Borregaard N
Methods for quantitation of human neutrophil proteins, a survey.
Journal of immunological methods 1999;232(1-2):179-90.
1999: Sengelov H; Borregaard N
Free-flow electrophoresis in subcellular fractionation of human neutrophils.
Journal of immunological methods 1999;232(1-2):145-52.
1999: Kjeldsen L; Sengelov H; Borregaard N
Subcellular fractionation of human neutrophils on Percoll density gradients.
Journal of immunological methods 1999;232(1-2):131-43.
1999: Bratt T; Ohlson S; Borregaard N
Interactions between neutrophil gelatinase-associated lipocalin and natural lipophilic ligands.
Biochimica et biophysica acta 1999;1472(1-2):262-9.
1999: Rudd P M; Mattu T S; Masure S; Bratt T; Van den Steen P E; Wormald M R; Küster B; Harvey D J; Borregaard N; Van Damme J; Dwek R A; Opdenakker G
Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
Biochemistry 1999;38(42):13937-50.
1999: Nielsen O H; Gionchetti P; Ainsworth M; Vainer B; Campieri M; Borregaard N; Kjeldsen L
Rectal dialysate and fecal concentrations of neutrophil gelatinase-associated lipocalin, interleukin-8, and tumor necrosis factor-alpha in ulcerative colitis.
The American journal of gastroenterology 1999;94(10):2923-8.
1999: Sørensen O; Bratt T; Johnsen A H; Madsen M T; Borregaard N
The human antibacterial cathelicidin, hCAP-18, is bound to lipoproteins in plasma.
The Journal of biological chemistry 1999;274(32):22445-51.
1999: Frohm Nilsson M; Sandstedt B; Sørensen O; Weber G; Borregaard N; Ståhle-Bäckdahl M
The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6.
Infection and immunity 1999;67(5):2561-6.
1998: Arnljots K; Sørensen O; Lollike K; Borregaard N
Timing, targeting and sorting of azurophil granule proteins in human myeloid cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(11):1789-95.
1998: Volck B; Price P A; Johansen J S; Sørensen O; Benfield T L; Nielsen H J; Calafat J; Borregaard N
YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils.
Proceedings of the Association of American Physicians 1998;110(4):351-60.
1998: Kjeldsen L; Calafat J; Borregaard N
Giant granules of neutrophils in Chediak-Higashi syndrome are derived from azurophil granules but not from specific and gelatinase granules.
Journal of leukocyte biology 1998;64(1):72-7.
1998: Lollike K; Borregaard N; Lindau M
Capacitance flickers and pseudoflickers of small granules, measured in the cell-attached configuration.
Biophysical journal 1998;75(1):53-9.
1998: Strong R K; Bratt T; Cowland J B; Borregaard N; Wiberg F C; Ewald A J
Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin (NGAL).
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):93-5.
1997: Borregaard N
Development of neutrophil granule diversity.
Annals of the New York Academy of Sciences 1997;832():62-8.
1997: Nielsen B S; Sehested M; Kjeldsen L; Borregaard N; Rygaard J; Danø K
Expression of matrix metalloprotease-9 in vascular pericytes in human breast cancer.
Laboratory investigation; a journal of technical methods and pathology 1997;77(4):345-55.
1997: Cowland J B; Borregaard N
Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans.
Genomics 1997;45(1):17-23.
1997: Sørensen O; Arnljots K; Cowland J B; Bainton D F; Borregaard N
The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils.
Blood 1997;90(7):2796-803.
1997: Sørensen O; Cowland J B; Askaa J; Borregaard N
An ELISA for hCAP-18, the cathelicidin present in human neutrophils and plasma.
Journal of immunological methods 1997;206(1-2):53-9.
1997: Morgan C P; Sengelov H; Whatmore J; Borregaard N; Cockcroft S
ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.
The Biochemical journal 1997;325 ( Pt 3)():581-5.
1997: Borregaard N; Cowland J B
Granules of the human neutrophilic polymorphonuclear leukocyte.
Blood 1997;89(10):3503-21.
1997: Le Cabec V; Calafat J; Borregaard N
Sorting of the specific granule protein, NGAL, during granulocytic maturation of HL-60 cells.
Blood 1997;89(6):2113-21.
1996: Röpke C; Gladstone P; Nielsen M; Borregaard N; Ledbetter J A; Svejgaard A; Odum N
Apoptosis following interleukin-2 withdrawal from T cells: evidence for a regulatory role of CD18 (beta 2-integrin) molecules.
Tissue antigens 1996;48(2):127-35.
1996: Downey G P; Butler J R; Brumell J; Borregaard N; Kjeldsen L; Sue-A-Quan A K; Grinstein S
Chemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmannin.
The Journal of biological chemistry 1996;271(35):21005-1011.
1996: Kjeldsen L; Sengeløv H; Lollike K; Borregaard N
Granules and secretory vesicles in human neonatal neutrophils.
Pediatric research 1996;40(1):120-9.
1996: Nanda A; Brumell J H; Nordström T; Kjeldsen L; Sengelov H; Borregaard N; Rotstein O D; Grinstein S
Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases.
The Journal of biological chemistry 1996;271(27):15963-70.
1996: Le Cabec V; Cowland J B; Calafat J; Borregaard N
Targeting of proteins to granule subsets is determined by timing and not by sorting: The specific granule protein NGAL is localized to azurophil granules when expressed in HL-60 cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6454-7.
1996: Nielsen B S; Borregaard N; Bundgaard J R; Timshel S; Sehested M; Kjeldsen L
Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases.
Gut 1996;38(3):414-20.
1996: Kjeldsen L; Cowland J B; Johnsen A H; Borregaard N
SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein.
FEBS letters 1996;380(3):246-50.
1996: Borregaard N
Current concepts about neutrophil granule physiology.
Current opinion in hematology 1996;3(1):11-8.
1996: Nielsen B S; Timshel S; Kjeldsen L; Sehested M; Pyke C; Borregaard N; Danø K
92 kDa type IV collagenase (MMP-9) is expressed in neutrophils and macrophages but not in malignant epithelial cells in human colon cancer.
International journal of cancer. Journal international du cancer 1996;65(1):57-62.
1995: Brumell J H; Volchuk A; Sengelov H; Borregaard N; Cieutat A M; Bainton D F; Grinstein S; Klip A
Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(12):5750-9.
1995: Lollike K; Sørensen O; Bundgaard J R; Segal A W; Boyhan A; Borregaard N
An ELISA for grancalcin, a novel cytosolic calcium-binding protein present in leukocytes.
Journal of immunological methods 1995;185(1):1-8.
1995: Cowland J B; Johnsen A H; Borregaard N
hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules.
FEBS letters 1995;368(1):173-6.
1995: Borregaard N; Kjeldsen L; Lollike K; Sengeløv H
Granules and secretory vesicles of the human neutrophil.
Clinical and experimental immunology 1995;101 Suppl 1():6-9.
1995: Sengeløv H; Follin P; Kjeldsen L; Lollike K; Dahlgren C; Borregaard N
Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):4157-65.
1995: Lollike K; Borregaard N; Lindau M
The exocytotic fusion pore of small granules has a conductance similar to an ion channel.
The Journal of cell biology 1995;129(1):99-104.
1995: Borregaard N; Sehested M; Nielsen B S; Sengeløv H; Kjeldsen L
Biosynthesis of granule proteins in normal human bone marrow cells. Gelatinase is a marker of terminal neutrophil differentiation.
Blood 1995;85(3):812-7.
1995: Lollike K; Kjeldsen L; Sengeløv H; Borregaard N
Purification of lysozyme from human neutrophils, and development of an ELISA for quantification in cells and plasma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(1):206-9.
1995: Lollike K; Kjeldsen L; Sengeløv H; Borregaard N
Lysozyme in human neutrophils and plasma. A parameter of myelopoietic activity.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(1):159-64.
1994: Bundgaard J R; Sengeløv H; Borregaard N; Kjeldsen L
Molecular cloning and expression of a cDNA encoding NGAL: a lipocalin expressed in human neutrophils.
Biochemical and biophysical research communications 1994;202(3):1468-75.
1994: Sengeløv H; Kjeldsen L; Kroeze W; Berger M; Borregaard N
Secretory vesicles are the intracellular reservoir of complement receptor 1 in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(2):804-10.
1994: Borregaard N; Kjeldsen L; Sengeløv H; Diamond M S; Springer T A; Anderson H C; Kishimoto T K; Bainton D F
Changes in subcellular localization and surface expression of L-selectin, alkaline phosphatase, and Mac-1 in human neutrophils during stimulation with inflammatory mediators.
Journal of leukocyte biology 1994;56(1):80-7.
1994: Sengeløv H; Boulay F; Kjeldsen L; Borregaard N
Subcellular localization and translocation of the receptor for N-formylmethionyl-leucyl-phenylalanine in human neutrophils.
The Biochemical journal 1994;299 ( Pt 2)():473-9.
1994: Kjeldsen L; Sengeløv H; Lollike K; Nielsen M H; Borregaard N
Isolation and characterization of gelatinase granules from human neutrophils.
Blood 1994;83(6):1640-9.
1994: Kjeldsen L; Bainton D F; Sengeløv H; Borregaard N
Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils.
Blood 1994;83(3):799-807.
1993: Borregaard N; Kjeldsen L; Lollike K; Sengeløv H
Granules and vesicles of human neutrophils. The role of endomembranes as source of plasma membrane proteins.
European journal of haematology 1993;51(5):318-22.
1993: Kjeldsen L; Bainton D F; Sengeløv H; Borregaard N
Structural and functional heterogeneity among peroxidase-negative granules in human neutrophils: identification of a distinct gelatinase-containing granule subset by combined immunocytochemistry and subcellular fractionation.
Blood 1993;82(10):3183-91.
1993: Borregaard N; Lollike K; Kjeldsen L; Sengeløv H; Bastholm L; Nielsen M H; Bainton D F
Human neutrophil granules and secretory vesicles.
European journal of haematology 1993;51(4):187-98.
1993: Sengeløv H; Kjeldsen L; Diamond M S; Springer T A; Borregaard N
Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils.
The Journal of clinical investigation 1993;92(3):1467-76.
1993: Kjeldsen L; Johnsen A H; Sengeløv H; Borregaard N
Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase.
The Journal of biological chemistry 1993;268(14):10425-32.
1993: Borregaard N; Kjeldsen L; Sengeløv H
Mobilization of granules in neutrophils from patients with myeloproliferative disorders.
European journal of haematology 1993;50(4):189-99.
1993: Sengeløv H; Kjeldsen L; Borregaard N
Control of exocytosis in early neutrophil activation.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1535-43.
1992: Kjeldsen L; Bjerrum O W; Hovgaard D; Johnsen A H; Sehested M; Borregaard N
Human neutrophil gelatinase: a marker for circulating blood neutrophils. Purification and quantitation by enzyme linked immunosorbent assay.
European journal of haematology 1992;49(4):180-91.
1992: Kjeldsen L; Bjerrum O W; Askaa J; Borregaard N
Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules.
The Biochemical journal 1992;287 ( Pt 2)():603-10.
1992: Sengeløv H; Nielsen M H; Borregaard N
Separation of human neutrophil plasma membrane from intracellular vesicles containing alkaline phosphatase and NADPH oxidase activity by free flow electrophoresis.
The Journal of biological chemistry 1992;267(21):14912-7.
1992: Borregaard N; Kjeldsen L; Rygaard K; Bastholm L; Nielsen M H; Sengeløv H; Bjerrum O W; Johnsen A H
Stimulus-dependent secretion of plasma proteins from human neutrophils.
The Journal of clinical investigation 1992;90(1):86-96.
1992: Borregaard N; Kjeldsen L; Lollike K; Sengeløv H
Ca(2+)-dependent translocation of cytosolic proteins to isolated granule subpopulations and plasma membrane from human neutrophils.
FEBS letters 1992;304(2-3):195-7.
1989: Bjerrum O W; Nielsen H; Borregaard N
Quantitative analysis of phospholipids and demonstration of plasmalogen in human neutrophil subcellular fractions by high-performance liquid chromatography.
Scandinavian journal of clinical and laboratory investigation 1989;49(7):613-22.
1989: Bjerrum O W; Borregaard N
Dual granule localization of the dormant NADPH oxidase and cytochrome b559 in human neutrophils.
European journal of haematology 1989;43(1):67-77.
1989: Borregaard N; Rasmussen N
Constituents of the human neutrophil cytoplasm: methods for examination and methodological problems with special reference to the binding site of the anti-neutrophil cytoplasmic antibodies.
APMIS. Supplementum 1989;6():10-1.
1988: Kjersem H; Hilsted J; Madsbad S; Wandall J H; Johansen K S; Borregaard N
Polymorphonuclear leucocyte dysfunction during short term metabolic changes from normo- to hyperglycemia in type 1 (insulin dependent) diabetic patients.
Infection 1988;16(4):215-21.
1987: Borregaard N; Jensen H S; Bjerrum O W
Prevention of tissue damage: inhibition of myeloperoxidase mediated inactivation of alpha 1-proteinase inhibitor by N-acetyl cysteine, glutathione, and methionine.
Agents and actions 1987;22(3-4):255-60.

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