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Marianne Thoresen

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X Liu; E Scull-Brown; P A Steen; J Dingley; Maja Elstad; Marianne Thoresen
Minimum alveolar concentration (MAC) for sevoflurane and xenon at normothermia and hypothermia in newborn pigs.
Marianne Thoresen; Damjan Osredkar
Brain wave recovery predicts outcome after cardiac arrest.
Kristian Aquilina; Ela Chakkarapani; Marianne Thoresen
Early deterioration of cerebrospinal fluid dynamics in a neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation.

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All Publications

2013: X Liu; E Scull-Brown; P A Steen; J Dingley; Maja Elstad; Marianne Thoresen
Minimum alveolar concentration (MAC) for sevoflurane and xenon at normothermia and hypothermia in newborn pigs.
Acta anaesthesiologica Scandinavica 2013;57(5):646-53.
2013: Marianne Thoresen; Damjan Osredkar
Brain wave recovery predicts outcome after cardiac arrest.
Resuscitation 2013;84(2):145-6.
2012: Kristian Aquilina; Ela Chakkarapani; Marianne Thoresen
Early deterioration of cerebrospinal fluid dynamics in a neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation.
Journal of neurosurgery. Pediatrics 2012;10(6):529-37.
2012: Marianne Thoresen; Xun Liu; Hemmen Sabir; Janet Stone; Emma Brown; Frances Cowan; Sally Jary; Mathias Karlsson
Lactate dehydrogenase in hypothermia-treated newborn infants with hypoxic-ischaemic encephalopathy.
Acta paediatrica (Oslo, Norway : 1992) 2012;101(10):1038-44.
2012: Hemmen Sabir; Sally Jary; Xun Liu; James Tooley; Marianne Thoresen
Increased inspired oxygen in the first hours of life is associated with adverse outcome in newborns treated for perinatal asphyxia with therapeutic hypothermia.
The Journal of pediatrics 2012;161(3):409-16.
2011: Maja Elstad; Andrew Whitelaw; Marianne Thoresen
Cerebral Resistance Index is less predictive in hypothermic encephalopathic newborns.
Acta paediatrica (Oslo, Norway : 1992) 2011;100(10):1344-9.
2011: Kristian Aquilina; Ela Chakkarapani; Hugh B Coakham; Ian K Pople; Marianne Thoresen; Richard J Edwards
Preliminary evaluation of a novel intraparenchymal capacitive intracranial pressure monitor.
Journal of neurosurgery 2011;115(3):561-9.
2011: Marianne Thoresen
Hypothermia after perinatal asphyxia: selection for treatment and cooling protocol.
The Journal of pediatrics 2011;158(2 Suppl):e45-9.
2011: Xun Liu; Ela Chakkarapani; Nicholas Hoque; Marianne Thoresen
Environmental cooling of the newborn pig brain during whole-body cooling.
Acta paediatrica (Oslo, Norway : 1992) 2011;100(1):29-35.
2010: Marianne Thoresen
Patient selection and prognostication with hypothermia treatment.
Seminars in fetal & neonatal medicine 2010;15(5):247-52.
2010: Elavazhagan Chakkarapani; John Dingley; Xun Liu; Nicholas Hoque; Kristian Aquilina; Helen Porter; Marianne Thoresen
Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs.
Annals of neurology 2010;68(3):330-41.
2010: Marianne Thoresen; Lena Hellström-Westas; Xun Liu; Linda S de Vries
Effect of hypothermia on amplitude-integrated electroencephalogram in infants with asphyxia.
Pediatrics 2010;126(1):e131-9.
2009: E Chakkarapani; D Harding; P Stoddart; R Garrett-Cox; Marianne Thoresen
Therapeutic hypothermia: surgical infant with neonatal encephalopathy.
Acta paediatrica (Oslo, Norway : 1992) 2009;98(11):1844-6.
2009: Ela Chakkarapani; Marianne Thoresen; Catherine E Hobbs; Kristian Aquilina; Xun Liu; John Dingley
A closed-circuit neonatal xenon delivery system: a technical and practical neuroprotection feasibility study in newborn pigs.
Anesthesia and analgesia 2009;109(2):451-60.
2009: Marianne Thoresen; Catherine E Hobbs; Tommy Wood; Ela Chakkarapani; John Dingley
Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(4):707-14.
2009: Mathias Karlsson; Saulius Satas; Janet Stone; Helen Porter; Marianne Thoresen
Liver enzymes cannot be used to predict liver damage after global hypoxia-ischemia in a neonatal pig model.
Neonatology 2009;96(4):211-8.
2009: Alexander M Tucker; Kristian Aquilina; Ela Chakkarapani; Catherine E Hobbs; Marianne Thoresen
Development of amplitude-integrated electroencephalography and interburst interval in the rat.
Pediatric research 2009;65(1):62-6.
2008: Marianne Thoresen
Supportive care during neuroprotective hypothermia in the term newborn: adverse effects and their prevention.
Clinics in perinatology 2008;35(4):749-63, vii.
2008: Kristian Aquilina; Catherine Hobbs; Alexander Tucker; Andrew Whitelaw; Marianne Thoresen
Do drugs that block transforming growth factor beta reduce posthaemorrhagic ventricular dilatation in a neonatal rat model?
Acta paediatrica (Oslo, Norway : 1992) 2008;97(9):1181-6.
2008: Mathias Karlsson; James Tooley; Saulius Satas; Catherine E Hobbs; Ela Chakkarapani; Janet Stone; Helen Porter; Marianne Thoresen
Delayed hypothermia as selective head cooling or whole body cooling does not protect brain or body in newborn pig subjected to hypoxia-ischemia.
Pediatric research 2008;64(1):74-8.
2008: Catherine Hobbs; Marianne Thoresen; Alexander Tucker; Kristian Aquilina; Ela Chakkarapani; John Dingley
Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia.
Stroke; a journal of cerebral circulation 2008;39(4):1307-13.
2008: John Dingley; Catherine Hobbs; James Ferguson; Janet Stone; Marianne Thoresen
Xenon/hypothermia neuroprotection regimes in spontaneously breathing neonatal rats after hypoxic-ischemic insult: the respiratory and sedative effects.
Anesthesia and analgesia 2008;106(3):916-23, table of contents.
2008: Alistair J Gunn; John S Wyatt; Andrew Whitelaw; John D E Barks; Denis Azzopardi; Roberta Ballard; A David Edwards; Donna M Ferriero; Peter D Gluckman; Richard A Polin; Charlene M Robertson; Marianne Thoresen
Therapeutic hypothermia changes the prognostic value of clinical evaluation of neonatal encephalopathy.
The Journal of pediatrics 2008;152(1):55-8, 58.e1.
2008: Pierre Gressens; John Dingley; Frank Plaisant; Helen Porter; Leslie Schwendimann; Catherine Verney; James Tooley; Marianne Thoresen
Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain.
Brain pathology (Zurich, Switzerland) 2008;18(1):10-20.
2007: John S Wyatt; Peter D Gluckman; Ping Y Liu; Denis Azzopardi; Roberta Ballard; A David Edwards; Donna M Ferriero; Richard A Polin; Charlene M Robertson; Marianne Thoresen; Andrew Whitelaw; Alistair J Gunn
Determinants of outcomes after head cooling for neonatal encephalopathy.
Pediatrics 2007;119(5):912-21.
2007: Andrew Whitelaw; David Evans; Michael Carter; Marianne Thoresen; Jolanta Wroblewska; Marek Mandera; Janusz Swietlinski; Judith Simpson; Constantinos Hajivassiliou; Linda P Hunt; Ian Pople
Randomized clinical trial of prevention of hydrocephalus after intraventricular hemorrhage in preterm infants: brain-washing versus tapping fluid.
Pediatrics 2007;119(5):e1071-8.
2006: Alistair J Gunn; Marianne Thoresen
Hypothermic neuroprotection.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2006;3(2):154-69.
2006: John Dingley; James Tooley; Helen Porter; Marianne Thoresen
Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia.
Stroke; a journal of cerebral circulation 2006;37(2):501-6.
2005: Mary A Rutherford; Denis Azzopardi; Andrew Whitelaw; Frances M Cowan; S Renowden; A David Edwards; Marianne Thoresen
Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy.
Pediatrics 2005;116(4):1001-6.
2005: James Tooley; R C Eagle; Saulius Satas; Marianne Thoresen
Significant head cooling can be achieved while maintaining normothermia in the newborn piglet.
Archives of disease in childhood. Fetal and neonatal edition 2005;90(3):F262-6.
2005: Marianne Thoresen; Andrew Whitelaw
Therapeutic hypothermia for hypoxic-ischaemic encephalopathy in the newborn infant.
Current opinion in neurology 2005;18(2):111-6.
2005: Karin Sävman; Ulf A Nilsson; Marianne Thoresen; Ingemar Kjellmer
Non-protein-bound iron in brain interstitium of newborn pigs after hypoxia.
Developmental neuroscience 2005;27(2-4):176-84.
2005: Peter D Gluckman; John S Wyatt; Denis Azzopardi; Roberta Ballard; A David Edwards; Donna M Ferriero; Richard A Polin; Charlene M Robertson; Marianne Thoresen; Andrew Whitelaw; Alistair J Gunn
Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial.
Lancet 2005;365(9460):663-70.
2004: Shobha Cherian; Marianne Thoresen; Ian A Silver; Andrew Whitelaw; Seth Love
Transforming growth factor-betas in a rat model of neonatal posthaemorrhagic hydrocephalus.
Neuropathology and applied neurobiology 2004;30(6):585-600.
2004: Shobha Cherian; Andrew Whitelaw; Marianne Thoresen; Seth Love
The pathogenesis of neonatal post-hemorrhagic hydrocephalus.
Brain pathology (Zurich, Switzerland) 2004;14(3):305-11.
2004: Andrew Whitelaw; Shobha Cherian; Marianne Thoresen; Ian Pople
Posthaemorrhagic ventricular dilatation: new mechanisms and new treatment.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2004;93(444):11-4.
2003: Maria Erecinska; Marianne Thoresen; Ian A Silver
Effects of hypothermia on energy metabolism in Mammalian central nervous system.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(5):513-30.
2003: Drude Fugelseth; Saulius Satas; P A Steen; Marianne Thoresen
Cardiac output, pulmonary artery pressure, and patent ductus arteriosus during therapeutic cooling after global hypoxia-ischaemia.
Archives of disease in childhood. Fetal and neonatal edition 2003;88(3):F223-8.
2003: Andrew Whitelaw; Ian Pople; Shobha Cherian; David Evans; Marianne Thoresen
Phase 1 trial of prevention of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy.
Pediatrics 2003;111(4 Pt 1):759-65.
2003: Shobha Cherian; Seth Love; Ian A Silver; Helen Porter; Andrew Whitelaw; Marianne Thoresen
Posthemorrhagic ventricular dilation in the neonate: development and characterization of a rat model.
Journal of neuropathology and experimental neurology 2003;62(3):292-303.
2003: Saulius Satas; EM Løberg; H Porter; A Whitelaw; P A Steen; Marianne Thoresen
Effect of global hypoxia-ischaemia followed by 24 h of mild hypothermia on organ pathology and biochemistry in a newborn pig survival model.
Biology of the neonate 2003;83(2):146-56.
2003: James Tooley; Saulius Satas; Helen Porter; Ian A Silver; Marianne Thoresen
Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective.
Annals of neurology 2003;53(1):65-72.
2002: Andrew Whitelaw; Marianne Thoresen
Clinical trials of treatments after perinatal asphyxia.
Current opinion in pediatrics 2002;14(6):664-8.
2002: James Tooley; Saulius Satas; Rebecca Eagle; Ian A Silver; Marianne Thoresen
Significant selective head cooling can be maintained long-term after global hypoxia ischemia in newborn piglets.
Pediatrics 2002;109(4):643-9.
2002: Andrew Whitelaw; Marianne Thoresen; Ian Pople
Posthaemorrhagic ventricular dilatation.
Archives of disease in childhood. Fetal and neonatal edition 2002;86(2):F72-4.
2002: Karin Sävman; M Blennow; Henrik Hagberg; Elisabeth Tarkowski; Marianne Thoresen; Andrew Whitelaw
Cytokine response in cerebrospinal fluid from preterm infants with posthaemorrhagic ventricular dilatation.
Acta paediatrica (Oslo, Norway : 1992) 2002;91(12):1357-63.
2001: M Blennow; Karin Sävman; P Ilves; Marianne Thoresen; L Rosengren
Brain-specific proteins in the cerebrospinal fluid of severely asphyxiated newborn infants.
Acta paediatrica (Oslo, Norway : 1992) 2001;90(10):1171-5.
2001: Marianne Thoresen; Saulius Satas; EM Løberg; A Whitelaw; D Acolet; C Lindgren; JM Penrice; N Robertson; E Haug; PA Steen
Twenty-four hours of mild hypothermia in unsedated newborn pigs starting after a severe global hypoxic-ischemic insult is not neuroprotective.
Pediatric research 2001;50(3):405-11.
2001: Marianne Thoresen; M Simmonds; Saulius Satas; James Tooley; Ian A Silver
Effective selective head cooling during posthypoxic hypothermia in newborn piglets.
Pediatric research 2001;49(4):594-9.
2001: Andrew Whitelaw; Marianne Thoresen
Clinical experience with therapeutic hypothermia in asphyxiated infants.
Developmental medicine and child neurology. Supplement 2001;86():30-1.
2000: Andrew Whitelaw; Marianne Thoresen
Antenatal steroids and the developing brain.
Archives of disease in childhood. Fetal and neonatal edition 2000;83(2):F154-7.
2000: Marianne Thoresen; Andrew Whitelaw
Cardiovascular changes during mild therapeutic hypothermia and rewarming in infants with hypoxic-ischemic encephalopathy.
Pediatrics 2000;106(1 Pt 1):92-9.
2000: Marianne Thoresen
Cooling the newborn after asphyxia - physiological and experimental background and its clinical use.
Seminars in neonatology : SN 2000;5(1):61-73.
2000: Saulius Satas; N O Hoem; Kjetil K Melby; H Porter; C G Lindgren; A Whitelaw; Marianne Thoresen
Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs.
Biology of the neonate 2000;77(1):50-7.
1999: Marianne Thoresen
Cooling the asphyxiated brain - ready for clinical trials?
European journal of pediatrics 1999;158 Suppl 1():S5-8.
1999: Drude Fugelseth; Saulius Satas; M Runde; P Hågå; Marianne Thoresen
Cardiac function and morphology studied by two-dimensional Doppler echocardiography in unsedated newborn pigs.
Experimental physiology 1999;84(1):69-78.
1998: Marianne Thoresen; A Hallström; A Whitelaw; M Puka-Sundvall; EM Løberg; Saulius Satas; Urban Ungerstedt; PA Steen; Henrik Hagberg
Lactate and pyruvate changes in the cerebral gray and white matter during posthypoxic seizures in newborn pigs.
Pediatric research 1998;44(5):746-54.
1998: E Bona; Henrik Hagberg; EM Løberg; Ralph Bågenholm; Marianne Thoresen
Protective effects of moderate hypothermia after neonatal hypoxia-ischemia: short- and long-term outcome.
Pediatric research 1998;43(6):738-45.
1998: PN Amess; JM Penrice; S Howard; Marianne Thoresen; A David Edwards; Ernest B Cady; John S Wyatt; VR Sams
Organ pathology following mild hypothermia used as neural rescue therapy in newborn piglets.
Biology of the neonate 1998;73(1):40-6.
1997: John S Wyatt; Marianne Thoresen
Hypothermia treatment and the newborn.
Pediatrics 1997;100(6):1028-30.
1997: Marianne Thoresen; Saulius Satas; M Puka-Sundvall; A Whitelaw; A Hallström; EM Løberg; Urban Ungerstedt; PA Steen; Henrik Hagberg
Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins.
Neuroreport 1997;8(15):3359-62.
1997: Saulius Satas; S I Johannessen; N O Hoem; K Haaland; D R Sørensen; Marianne Thoresen
Lidocaine pharmacokinetics and toxicity in newborn pigs.
Anesthesia and analgesia 1997;85(2):306-12.
1997: PN Amess; JM Penrice; Ernest B Cady; A Lorek; Marzena Wylezinska; Chris E Cooper; P D'Souza; L Tyszczuk; Marianne Thoresen; A David Edwards; John S Wyatt; EO Reynolds
Mild hypothermia after severe transient hypoxia-ischemia reduces the delayed rise in cerebral lactate in the newborn piglet.
Pediatric research 1997;41(6):803-8.
1997: K Haaland; EM Løberg; PA Steen; Marianne Thoresen
Posthypoxic hypothermia in newborn piglets.
Pediatric research 1997;41(4 Pt 1):505-12.
1996: Marianne Thoresen; K Haaland; EM Løberg; A Whitelaw; F Apricena; E Hankø; PA Steen
A piglet survival model of posthypoxic encephalopathy.
Pediatric research 1996;40(5):738-48.
1996: Saulius Satas; K Haaland; Marianne Thoresen; PA Steen
MAC for halothane and isoflurane during normothermia and hypothermia in the newborn piglet.
Acta anaesthesiologica Scandinavica 1996;40(4):452-6.
1996: Marianne Thoresen; Ralph Bågenholm; EM Løberg; F Apriccna
The stress of being restrained reduces brain damage after a hypoxic-ischaemic insult in the 7-day-old rat.
Neuroreport 1996;7(2):481-4.
1996: K Haaland; J Kofstad; F Apricena; Marianne Thoresen
Haemoglobin is inversely related to plasma lactate and heart rate in the newborn piglet.
Biology of the neonate 1996;69(5):350-6.
1996: K Haaland; PA Steen; Marianne Thoresen
Cerebral, tympanic and colonic thermometry in the piglet.
Reproduction, fertility, and development 1996;8(1):125-8.
1996: Marianne Thoresen; Ralph Bågenholm; EM Løberg; F Apricena; Ingemar Kjellmer
Posthypoxic cooling of neonatal rats provides protection against brain injury.
Archives of disease in childhood. Fetal and neonatal edition 1996;74(1):F3-9.
1995: A David Edwards; X Yue; M V Squier; Marianne Thoresen; Ernest B Cady; JM Penrice; Chris E Cooper; John S Wyatt; EO Reynolds; Huseyin Mehmet
Specific inhibition of apoptosis after cerebral hypoxia-ischaemia by moderate post-insult hypothermia.
Biochemical and biophysical research communications 1995;217(3):1193-9.
1995: Marianne Thoresen; JM Penrice; A Lorek; Ernest B Cady; Marzena Wylezinska; V Kirkbride; Chris E Cooper; G C Brown; A David Edwards; John S Wyatt
Mild hypothermia after severe transient hypoxia-ischemia ameliorates delayed cerebral energy failure in the newborn piglet.
Pediatric research 1995;37(5):667-70.
1995: K Haaland; W J Orderud; Marianne Thoresen
The piglet as a model for cerebral circulation: an angiographic study.
Biology of the neonate 1995;68(1):75-80.
1994: K Haaland; B Karlsson; E Skovlund; Marianne Thoresen
Simultaneous measurements of cerebral circulation with electromagnetic flowmetry and Doppler ultrasound velocity in the newborn pig.
Pediatric research 1994;36(5):601-6.
1994: Marianne Thoresen; K Haaland; PA Steen
Cerebral Doppler and misrepresentation of flow changes.
Archives of disease in childhood 1994;71(2):F103-6.
1992: K Haaland; Marianne Thoresen
[Crib death, sleeping position and temperature].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1992;112(11):1466-70.
1991: A Whitelaw; B R Karlsson; K Haaland; I Dahlin; PA Steen; Marianne Thoresen
Hypocapnia and cerebral ischaemia in hypotensive newborn piglets.
Archives of disease in childhood 1991;66(10 Spec No):1110-4.