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Jeremy Thorner

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Phenomena

Physiology

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Co-Publications
Name
8
Bardwell, Lee
7
Cook, Jeanette Gowen
7
Strahl, Thomas
6
Martin, Steven
6
Blumer, Kendall
5
Dohlman, Henrik
5
Inouye, Carla
4
Shulewitz, Mark
4
Fuller, Robert
4
Chen, Raymond
4
Cid, Víctor
3
Dhillon, N
3
Ames, James
3
Torrance, Pamela
3
Versele, Matthias

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Publications

TOP 3
Rockwell Nathan C; Wolfger Hubert; Kuchler Karl; Thorner Jeremy
ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae.
McMurray Michael A; Thorner Jeremy
Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast.
Garrenton Lindsay S; Braunwarth Andreas; Irniger Stefan; Hurt Ed; Künzler Markus; Thorner Jeremy
Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.

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All Publications

2009: Rockwell Nathan C; Wolfger Hubert; Kuchler Karl; Thorner Jeremy
ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae.
The Journal of membrane biology 2009;229(1):27-52.
2009: McMurray Michael A; Thorner Jeremy
Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast.
Cell cycle (Georgetown, Tex.) 2009;8(2):195-203.
2009: Garrenton Lindsay S; Braunwarth Andreas; Irniger Stefan; Hurt Ed; Künzler Markus; Thorner Jeremy
Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.
Molecular and cellular biology 2009;29(2):582-601.
2009: McMurray Michael A; Thorner Jeremy
Septins: molecular partitioning and the generation of cellular asymmetry.
Cell division 2009;4():18.
2008: Westfall Patrick J; Patterson Jesse C; Chen Raymond E; Thorner Jeremy
Stress resistance and signal fidelity independent of nuclear MAPK function.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12212-7.
2008: McMurray Michael A; Thorner Jeremy
Septin stability and recycling during dynamic structural transitions in cell division and development.
Current biology : CB 2008;18(16):1203-8.
2008: Bertin Aurelie; McMurray Michael A; Grob Patricia; Park Sang-Shin; Garcia Galo; Patanwala Insiyyah; Ng Ho-Leung; Alber Tom; Thorner Jeremy; Nogales Eva
Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(24):8274-9.
2007: Blumer Kendall J; Thorner Jeremy
An adrenaline (and gold?) rush for the GPCR community.
ACS chemical biology 2007;2(12):783-6.
2007: Schüller Christoph; Mamnun Yasmine M; Wolfger Hubert; Rockwell Nathan; Thorner Jeremy; Kuchler Karl
Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae.
Molecular biology of the cell 2007;18(12):4932-44.
2007: Strahl Thomas; Huttner Inken G; Lusin Jacqueline D; Osawa Masanori; King David; Thorner Jeremy; Ames James B
Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).
The Journal of biological chemistry 2007;282(42):30949-59.
2007: Chen Raymond E; Thorner Jeremy
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.
Biochimica et biophysica acta 2007;1773(8):1311-40.
2007: Strahl Thomas; Thorner Jeremy
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.
Biochimica et biophysica acta 2007;1771(3):353-404.
2006: Ballon Daniel R; Flanary Paul L; Gladue Douglas P; Konopka James B; Dohlman Henrik G; Thorner Jeremy
DEP-domain-mediated regulation of GPCR signaling responses.
Cell 2006;126(6):1079-93.
2006: Asano Satoshi; Park Jung-Eun; Yu Li-Rong; Zhou Ming; Sakchaisri Krisada; Park Chong J; Kang Young H; Thorner Jeremy; Veenstra Timothy D; Lee Kyung S
Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast.
The Journal of biological chemistry 2006;281(37):27090-8.
2006: Westfall Patrick J; Thorner Jeremy
Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele.
Eukaryotic cell 2006;5(8):1215-28.
2006: Garrenton Lindsay S; Young Susan L; Thorner Jeremy
Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain.
Genes & development 2006;20(14):1946-58.
2006: Weirich Christine S; Erzberger Jan P; Flick Jeffrey S; Berger James M; Thorner Jeremy; Weis Karsten
Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export.
Nature cell biology 2006;8(7):668-76.
2006: Truckses Dagmar M; Bloomekatz Joshua E; Thorner Jeremy
The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae.
Molecular and cellular biology 2006;26(3):912-28.
2005: Strahl Thomas; Hama Hiroko; DeWald Daryll B; Thorner Jeremy
Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus.
The Journal of cell biology 2005;171(6):967-79.
2005: Rodríguez-Escudero Isabel; Roelants Françoise M; Thorner Jeremy; Nombela César; Molina María; Cid Víctor J
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
The Biochemical journal 2005;390(Pt 2):613-23.
2005: Versele Matthias; Thorner Jeremy
Some assembly required: yeast septins provide the instruction manual.
Trends in cell biology 2005;15(8):414-24.
2005: Chen Raymond E; Thorner Jeremy
Systems biology approaches in cell signaling research.
Genome biology 2005;6(10):235.
2004: Westfall Patrick J; Ballon Daniel R; Thorner Jeremy
When the stress of your environment makes you go HOG wild.
Science (New York, N.Y.) 2004;306(5701):1511-2.
2004: Truckses Dagmar M; Garrenton Lindsay S; Thorner Jeremy
Jekyll and Hyde in the microbial world.
Science (New York, N.Y.) 2004;306(5701):1509-11.
2004: Roelants Françoise M; Torrance Pamela D; Thorner Jeremy
Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9.
Microbiology (Reading, England) 2004;150(Pt 10):3289-304.
2004: Versele Matthias; Gullbrand Björn; Shulewitz Mark J; Cid Victor J; Bahmanyar Shirin; Chen Raymond E; Barth Patrick; Alber Tom; Thorner Jeremy
Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.
Molecular biology of the cell 2004;15(10):4568-83.
2004: Sakchaisri Krisada; Asano Satoshi; Yu Li-Rong; Shulewitz Mark J; Park Chong J; Park Jung-Eun; Cho Young-Wook; Veenstra Timothy D; Thorner Jeremy; Lee Kyung S
Coupling morphogenesis to mitotic entry.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4124-9.
2004: Versele Matthias; Thorner Jeremy
Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4.
The Journal of cell biology 2004;164(5):701-15.
2004: Rockwell Nathan C; Thorner Jeremy W
The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing.
Trends in biochemical sciences 2004;29(2):80-7.
2004: Rudge Simon A; Sciorra Vicki A; Iwamoto Michelle; Zhou Chun; Strahl Thomas; Morris Andrew J; Thorner Jeremy; Engebrecht JoAnne
Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation.
Molecular biology of the cell 2004;15(1):207-18.
2003: Strahl Thomas; Grafelmann Birgit; Dannenberg Jens; Thorner Jeremy; Pongs Olaf
Conservation of regulatory function in calcium-binding proteins: human frequenin (neuronal calcium sensor-1) associates productively with yeast phosphatidylinositol 4-kinase isoform, Pik1.
The Journal of biological chemistry 2003;278(49):49589-99.
2003: Wang Yuqi; Ge Qing; Houston Dayle; Thorner Jeremy; Errede Beverly; Dohlman Henrik G
Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex.
The Journal of biological chemistry 2003;278(25):22284-9.
2003: Huttner Inken G; Strahl Thomas; Osawa Masanori; King David S; Ames James B; Thorner Jeremy
Molecular interactions of yeast frequenin (Frq1) with the phosphatidylinositol 4-kinase isoform, Pik1.
The Journal of biological chemistry 2003;278(7):4862-74.
2002: Roelants Françoise M; Torrance Pamela D; Bezman Natalie; Thorner Jeremy
Pkh1 and pkh2 differentially phosphorylate and activate ypk1 and ykr2 and define protein kinase modules required for maintenance of cell wall integrity.
Molecular biology of the cell 2002;13(9):3005-28.
2002: Cid Víctor J; Jiménez Javier; Molina María; Sánchez Miguel; Nombela César; Thorner Jeremy W
Orchestrating the cell cycle in yeast: sequential localization of key mitotic regulators at the spindle pole and the bud neck.
Microbiology (Reading, England) 2002;148(Pt 9):2647-59.
2002: Rayner Timothy F; Gray Joseph V; Thorner Jeremy W
Direct and novel regulation of cAMP-dependent protein kinase by Mck1p, a yeast glycogen synthase kinase-3.
The Journal of biological chemistry 2002;277(19):16814-22.
2001: Thorner J W
Greasing the wheels of secretory transport.
Nature cell biology 2001;3(8):E196-8.
2001: Cid V J; Shulewitz M J; McDonald K L; Thorner J
Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle.
Molecular biology of the cell 2001;12(6):1645-69.
2001: Adamkewicz J I; Hansen K E; Prud'homme W A; Davis J L; Thorner J
High affinity interaction of yeast transcriptional regulator, Mot1, with TATA box-binding protein (TBP).
The Journal of biological chemistry 2001;276(15):11883-94.
2001: Künzler M; Trueheart J; Sette C; Hurt E; Thorner J
Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects.
Genetics 2001;157(3):1089-105.
2001: Bardwell A J; Flatauer L J; Matsukuma K; Thorner J; Bardwell L
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.
The Journal of biological chemistry 2001;276(13):10374-86.
2001: Dohlman H G; Thorner J W
Regulation of G protein-initiated signal transduction in yeast: paradigms and principles.
Annual review of biochemistry 2001;70():703-54.
2000: Sette C; Inouye C J; Stroschein S L; Iaquinta P J; Thorner J
Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein.
Molecular biology of the cell 2000;11(11):4033-49.
2000: Ames J B; Hendricks K B; Strahl T; Huttner I G; Hamasaki N; Thorner J
Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae.
Biochemistry 2000;39(40):12149-61.
2000: Adamkewicz J I; Mueller C G; Hansen K E; Prud'homme W A; Thorner J
Purification and enzymic properties of Mot1 ATPase, a regulator of basal transcription in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 2000;275(28):21158-68.
2000: Petersen C; Orem N; Trueheart J; Thorner J W; Macara I G
Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1.
The Journal of biological chemistry 2000;275(6):4081-91.
1999: Hama H; Schnieders E A; Thorner J; Takemoto J Y; DeWald D B
Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(48):34294-300.
1999: Shulewitz M J; Inouye C J; Thorner J
Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae.
Molecular and cellular biology 1999;19(10):7123-37.
1999: Hendricks K B; Wang B Q; Schnieders E A; Thorner J
Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase.
Nature cell biology 1999;1(4):234-41.
1999: Casamayor A; Torrance P D; Kobayashi T; Thorner J; Alessi D R
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.
Current biology : CB 1999;9(4):186-97.
1998: Bardwell L; Cook J G; Zhu-Shimoni J X; Voora D; Thorner J
Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15400-5.
1998: Bardwell L; Cook J G; Voora D; Baggott D M; Martinez A R; Thorner J
Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.
Genes & development 1998;12(18):2887-98.
1998: Stolz L E; Huynh C V; Thorner J; York J D
Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae.
Genetics 1998;148(4):1715-29.
1998: Flick J S; Thorner J
An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae.
Genetics 1998;148(1):33-47.
1997: Cook J G; Bardwell L; Thorner J
Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway.
Nature 1997;390(6655):85-8.
1997: Inouye C; Dhillon N; Durfee T; Zambryski P C; Thorner J
Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions.
Genetics 1997;147(2):479-92.
1997: Inouye C; Dhillon N; Thorner J
Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling.
Science (New York, N.Y.) 1997;278(5335):103-6.
1997: Brazill D T; Thorner J; Martin G S
Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae.
Journal of bacteriology 1997;179(13):4415-8.
1997: David N E; Gee M; Andersen B; Naider F; Thorner J; Stevens R C
Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor.
The Journal of biological chemistry 1997;272(24):15553-61.
1997: Wilson L K; Dhillon N; Thorner J; Martin G S
Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3.
The Journal of biological chemistry 1997;272(20):12961-7.
1997: Dohlman H G; Thorner J
RGS proteins and signaling by heterotrimeric G proteins.
The Journal of biological chemistry 1997;272(7):3871-4.
1996: Melcher M L; Thorner J
Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1996;271(47):29958-68.
1996: Cook J G; Bardwell L; Kron S J; Thorner J
Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.
Genes & development 1996;10(22):2831-48.
1996: Broach J R; Thorner J
High-throughput screening for drug discovery.
Nature 1996;384(6604 Suppl):14-6.
1996: Bardwell L; Thorner J
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs.
Trends in biochemical sciences 1996;21(10):373-4.
1996: Dohlman H G; Song J; Ma D; Courchesne W E; Thorner J
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).
Molecular and cellular biology 1996;16(9):5194-209.
1996: Bardwell L; Cook J G; Chang E C; Cairns B R; Thorner J
Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7.
Molecular and cellular biology 1996;16(7):3637-50.
1996: Swartzman E E; Viswanathan M N; Thorner J
The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae.
The Journal of cell biology 1996;132(4):549-63.
1995: Wilson L K; Benton B M; Zhou S; Thorner J; Martin G S
The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1.
The Journal of biological chemistry 1995;270(42):25185-93.
1995: Ma D; Cook J G; Thorner J
Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.
Molecular biology of the cell 1995;6(7):889-909.
1995: Harris E; Yaswen P; Thorner J
Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast.
Molecular & general genetics : MGG 1995;247(2):137-47.
1995: Jiang W; Lim M Y; Yoon H J; Thorner J; Martin G S; Carbon J
Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5.
Molecular & general genetics : MGG 1995;246(3):360-6.
1994: Salama S R; Hendricks K B; Thorner J
G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover.
Molecular and cellular biology 1994;14(12):7953-66.
1994: Bardwell L; Cook J G; Inouye C J; Thorner J
Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae.
Developmental biology 1994;166(2):363-79.
1994: Harris E; Watterson D M; Thorner J
Functional consequences in yeast of single-residue alterations in a consensus calmodulin.
Journal of cell science 1994;107 ( Pt 11)():3235-49.
1994: Benton B M; Zang J H; Thorner J
A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.
The Journal of cell biology 1994;127(3):623-39.
1994: Auble D T; Hansen K E; Mueller C G; Lane W S; Thorner J; Hahn S
Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.
Genes & development 1994;8(16):1920-34.
1994: Perler F B; Davis E O; Dean G E; Gimble F S; Jack W E; Neff N; Noren C J; Thorner J; Belfort M
Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature.
Nucleic acids research 1994;22(7):1125-7.
1994: Florio M; Wilson L K; Trager J B; Thorner J; Martin G S
Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae.
Molecular biology of the cell 1994;5(3):283-96.
1994: Hasson M S; Blinder D; Thorner J; Jenness D D
Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.
Molecular and cellular biology 1994;14(2):1054-65.
1993: Flanagan C A; Schnieders E A; Emerick A W; Kunisawa R; Admon A; Thorner J
Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability.
Science (New York, N.Y.) 1993;262(5138):1444-8.
1993: Dohlman H G; Goldsmith P; Spiegel A M; Thorner J
Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9688-92.
1993: Gimble F S; Thorner J
Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1993;268(29):21844-53.
1993: Lim M Y; Dailey D; Martin G S; Thorner J
Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine.
The Journal of biological chemistry 1993;268(28):21155-64.
1993: Flick J S; Thorner J
Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae.
Molecular and cellular biology 1993;13(9):5861-76.
1993: Kuchler K; Dohlman H G; Thorner J
The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae.
The Journal of cell biology 1993;120(5):1203-15.
1992: Flanagan C A; Thorner J
Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1992;267(33):24117-25.
1992: Bremer M C; Gimble F S; Thorner J; Smith C L
VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene.
Nucleic acids research 1992;20(20):5484.
1992: Kuchler K; Thorner J
Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators.
Endocrine reviews 1992;13(3):499-514.
1992: Cyert M S; Thorner J
Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.
Molecular and cellular biology 1992;12(8):3460-9.
1992: Gimble F S; Thorner J
Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae.
Nature 1992;357(6376):301-6.
1992: Davis J L; Kunisawa R; Thorner J
A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(4):1879-92.
1992: Kuchler K; Thorner J
Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2302-6.
1992: Kuchler K; Göransson H M; Viswanathan M N; Thorner J
Dedicated transporters for peptide export and intercompartmental traffic in the yeast Saccharomyces cerevisiae.
Cold Spring Harbor symposia on quantitative biology 1992;57():579-92.
1991: Cyert M S; Kunisawa R; Kaim D; Thorner J
Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7376-80.
1991: Pausch M H; Kaim D; Kunisawa R; Admon A; Thorner J
Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote.
The EMBO journal 1991;10(6):1511-22.
1991: Blumer K J; Thorner J
Receptor-G protein signaling in yeast.
Annual review of physiology 1991;53():37-57.
1991: Fields F O; Thorner J
Genetic suppression analysis of the function of a protein kinase C (PKC1 gene product) in Saccharomyces cerevisiae cell cycle progression: the SKCd mutations.
Cold Spring Harbor symposia on quantitative biology 1991;56():51-60.
1991: Dohlman H G; Thorner J; Caron M G; Lefkowitz R J
Model systems for the study of seven-transmembrane-segment receptors.
Annual review of biochemistry 1991;60():653-88.
1990: Bresnahan P A; Leduc R; Thomas L; Thorner J; Gibson H L; Brake A J; Barr P J; Thomas G
Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.
The Journal of cell biology 1990;111(6 Pt 2):2851-9.
1990: Dailey D; Schieven G L; Lim M Y; Marquardt H; Gilmore T; Thorner J; Martin G S
Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity.
Molecular and cellular biology 1990;10(12):6244-56.
1990: Marr R S; Blair L C; Thorner J
Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone.
The Journal of biological chemistry 1990;265(33):20057-60.
1990: King K; Dohlman H G; Thorner J; Caron M G; Lefkowitz R J
Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit.
Science (New York, N.Y.) 1990;250(4977):121-3.
1990: Kuchler K; Thorner J
Membrane translocation of proteins without hydrophobic signal peptides.
Current opinion in cell biology 1990;2(4):617-24.
1990: Levin D E; Fields F O; Kunisawa R; Bishop J M; Thorner J
A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle.
Cell 1990;62(2):213-24.
1990: Blumer K J; Thorner J
Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4363-7.
1989: Kuchler K; Sterne R E; Thorner J
Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.
The EMBO journal 1989;8(13):3973-84.
1989: Yu L; Blumer K J; Davidson N; Lester H A; Thorner J
Functional expression of the yeast alpha-factor receptor in Xenopus oocytes.
The Journal of biological chemistry 1989;264(35):20847-50.
1989: Fuller R S; Brake A J; Thorner J
Intracellular targeting and structural conservation of a prohormone-processing endoprotease.
Science (New York, N.Y.) 1989;246(4929):482-6.
1989: Davis T N; Thorner J
Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):7909-13.
1989: Courchesne W E; Kunisawa R; Thorner J
A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae.
Cell 1989;58(6):1107-19.
1989: Schafer W R; Kim R; Sterne R; Thorner J; Kim S H; Rine J
Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.
Science (New York, N.Y.) 1989;245(4916):379-85.
1989: Cyert M S; Thorner J
Putting it on and taking it off: phosphoprotein phosphatase involvement in cell cycle regulation.
Cell 1989;57(6):891-3.
1989: Fuller R S; Brake A; Thorner J
Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1434-8.
1989: Flessel M C; Brake A J; Thorner J
The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements.
Genetics 1989;121(2):223-36.
1989: Foster R; Thorner J; Martin G S
Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria.
Journal of bacteriology 1989;171(1):272-9.
1988: Reneke J E; Blumer K J; Courchesne W E; Thorner J
The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain.
Cell 1988;55(2):221-34.
1988: Blumer K J; Reneke J E; Thorner J
The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.
The Journal of biological chemistry 1988;263(22):10836-42.
1988: Thomas G; Thorne B A; Thomas L; Allen R G; Hruby D E; Fuller R; Thorner J
Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells.
Science (New York, N.Y.) 1988;241(4862):226-30.
1988: Fuller R S; Sterne R E; Thorner J
Enzymes required for yeast prohormone processing.
Annual review of physiology 1988;50():345-62.
1988: Blumer K J; Reneke J E; Courchesne W E; Thorner J
Functional domains of a peptide hormone receptor: the alpha-factor receptor (STE2 gene product) of the yeast Saccharomyces cerevisiae.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():591-603.
1987: Whiteway M; Freedman R; Van Arsdell S; Szostak J W; Thorner J
The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus.
Molecular and cellular biology 1987;7(10):3713-22.
1987: Van Arsdell S W; Stetler G L; Thorner J
The yeast repeated element sigma contains a hormone-inducible promoter.
Molecular and cellular biology 1987;7(2):749-59.
1987: Kunisawa R; Davis T N; Urdea M S; Thorner J
Complete nucleotide sequence of the gene encoding the regulatory subunit of 3',5'-cyclic AMP-dependent protein kinase from the yeast Saccharomyces cerevisiae.
Nucleic acids research 1987;15(1):368-9.
1987: Davis T N; Thorner J
Isolation of the yeast calmodulin gene using synthetic oligonucleotide probes.
Methods in enzymology 1987;139():248-62.
1986: Davis T N; Urdea M S; Masiarz F R; Thorner J
Isolation of the yeast calmodulin gene: calmodulin is an essential protein.
Cell 1986;47(3):423-31.
1986: Barnes D A; Thorner J
Genetic manipulation of Saccharomyces cerevisiae by use of the LYS2 gene.
Molecular and cellular biology 1986;6(8):2828-38.
1986: Schieven G; Thorner J; Martin G S
Protein-tyrosine kinase activity in Saccharomyces cerevisiae.
Science (New York, N.Y.) 1986;231(4736):390-3.
1985: Thorner J
Pheromone-processing protease of the yeast Saccharomyces cerevisiae.
Nature 1985;314(6009):384-5.
1984: Julius D; Brake A; Blair L; Kunisawa R; Thorner J
Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor.
Cell 1984;37(3):1075-89.
1984: Julius D; Schekman R; Thorner J
Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway.
Cell 1984;36(2):309-18.
1984: Stetler G L; Thorner J
Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(4):1144-8.
1983: Emr S D; Schekman R; Flessel M C; Thorner J
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(23):7080-4.
1983: Brake A J; Julius D J; Thorner J
A functional prepro-alpha-factor gene in Saccharomyces yeasts can contain three, four, or five repeats of the mature pheromone sequence.
Molecular and cellular biology 1983;3(8):1440-50.
1983: Chan R K; Melnick L M; Blair L C; Thorner J
Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae.
Journal of bacteriology 1983;155(2):903-6.
1983: Julius D; Blair L; Brake A; Sprague G; Thorner J
Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase.
Cell 1983;32(3):839-52.
1983: Sprague G F; Blair L C; Thorner J
Cell interactions and regulation of cell type in the yeast Saccharomyces cerevisiae.
Annual review of microbiology 1983;37():623-60.
1982: Loumaye E; Thorner J; Catt K J
Yeast mating pheromone activates mammalian gonadotrophs: evolutionary conservation of a reproductive hormone?
Science (New York, N.Y.) 1982;218(4579):1323-5.
1982: Bisson L F; Thorner J
Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae.
Genetics 1982;102(3):341-59.
1982: Bisson L F; Thorner J
Exogenous dTMP utilization by a novel tup mutant of Saccharomyces cerevisiae.
Journal of bacteriology 1982;152(1):111-9.
1982: Thorner J
An essential role for cyclic AMP in growth control: the case for yeast.
Cell 1982;30(1):5-6.
1982: Bisson L F; Thorner J
Effect of halogenated pyrimidine 5'-mononucleotides on dTMP-permeable yeast strains and the isolation and characterization of resistant mutants.
Molecular & general genetics : MGG 1982;186(4):467-74.
1981: Bisson L F; Thorner J
Thymidylate synthetase from Saccharomyces cerevisiae. Purification and enzymic properties.
The Journal of biological chemistry 1981;256(23):12456-62.
1981: Liao H H; Thorner J
Adenosine 3',5'-phosphate phosphodiesterase and pheromone response in the yeast Saccharomyces cerevisiae.
Journal of bacteriology 1981;148(3):919-25.
1980: Liao H; Thorner J
Yeast mating pheromone alpha factor inhibits adenylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(4):1898-902.

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